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undecanoic acid - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:undecanoic acid
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Accession:CHEBI:32368 term browser browse the term
Definition:A straight-chain, eleven-carbon saturated medium-chain fatty acid found in body fluids; the most fungitoxic of the C7:0 - C18:0 fatty acid series.
Synonyms:related_synonym: 1-decanecarboxylic acid;   CH3-[CH2]9-COOH;   Formula=C11H22O2;   InChI=1S/C11H22O2/c1-2-3-4-5-6-7-8-9-10-11(12)13/h2-10H2,1H3,(H,12,13);   InChIKey=ZDPHROOEEOARMN-UHFFFAOYSA-N;   SMILES=CCCCCCCCCCC(O)=O;   UDA;   Undekansaeure;   hendecanoic acid;   n-undecanoic acid;   n-undecoic acid;   n-undecylic acid;   undecoic acid;   undecylic acid
 xref: CAS:112-37-8;   Gmelin:102992;   HMDB:HMDB0000947;   KEGG:C17715;   LIPID_MAPS_instance:LMFA01010011
 xref_mesh: MESH:C016173
 xref: PDBeChem:11A;   PMID:16332663;   PMID:1739406;   PMID:18516670;   Reaxys:1759287;   Wikipedia:Undecylic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:32369

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undecanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide multiple interactions ISO undecanoic acid inhibits the reaction [ADH5 protein results in increased reduction of S-Nitrosoglutathione] CTD PMID:19428350 NCBI chr 2:229,648,557...229,660,964
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
perfluoroundecanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression ISO perfluoroundecanoic acid results in decreased expression of A2M mRNA CTD PMID:23567314 NCBI chr 4:156,570,163...156,619,870
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 increases expression ISO perfluoroundecanoic acid results in increased expression of ABCA1 mRNA CTD PMID:35337807 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO perfluoroundecanoic acid results in increased expression of ACOT2 mRNA CTD PMID:35337807 NCBI chr 6:109,341,426...109,352,818
Ensembl chr 6:103,611,544...103,619,245 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation EXP perfluoroundecanoic acid results in decreased phosphorylation of AKT1 protein CTD PMID:33549592 PMID:35143807 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 decreases phosphorylation EXP perfluoroundecanoic acid results in decreased phosphorylation of AKT2 protein CTD PMID:33549592 PMID:35143807 NCBI chr 1:92,004,705...92,061,420
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO perfluoroundecanoic acid results in increased expression of ANGPTL4 mRNA CTD PMID:23567314 NCBI chr 7:15,252,450...15,259,971
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Apoa2 apolipoprotein A2 affects expression ISO perfluoroundecanoic acid affects the expression of APOA2 mRNA CTD PMID:23567314 NCBI chr13:86,176,767...86,178,819
Ensembl chr13:83,644,470...83,646,355 		JBrowse link
G Apoa4 apolipoprotein A4 affects expression EXP perfluoroundecanoic acid affects the expression of APOA4 mRNA CTD PMID:22071372 NCBI chr 8:55,435,779...55,438,160
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO perfluoroundecanoic acid results in increased expression of ATF3 mRNA CTD PMID:23567314 NCBI chr13:105,274,103...105,331,653
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon multiple interactions ISO [perfluoroundecanoic acid affects the methylation of ATP5F1E gene] which affects the expression of ATP5F1E mRNA CTD PMID:32653021 NCBI chr 3:183,677,270...183,680,172
Ensembl chr 3:163,260,476...163,261,450 		JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase decreases expression ISO perfluoroundecanoic acid results in decreased expression of BAAT mRNA CTD PMID:23567314 NCBI chr 5:68,647,166...68,656,137
Ensembl chr 5:63,850,705...63,860,685 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP perfluoroundecanoic acid results in increased expression of BAX mRNA; perfluoroundecanoic acid results in increased expression of BAX protein CTD PMID:33549592 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP perfluoroundecanoic acid results in decreased expression of BCL2 protein CTD PMID:33549592 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdh2 3-hydroxybutyrate dehydrogenase 2 increases expression ISO perfluoroundecanoic acid results in increased expression of BDH2 mRNA CTD PMID:35337807 NCBI chr 2:226,376,346...226,397,010
Ensembl chr 2:223,702,412...223,723,072 		JBrowse link
G Becn1 beclin 1 increases expression EXP perfluoroundecanoic acid results in increased expression of BECN1 protein CTD PMID:33549592 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 decreases expression ISO perfluoroundecanoic acid results in decreased expression of CCL20 protein CTD PMID:32916415 NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Cd36 CD36 molecule decreases expression
increases uptake		 ISO perfluoroundecanoic acid results in decreased expression of CD36 mRNA
CD36 protein results in increased uptake of perfluoroundecanoic acid		 CTD PMID:23567314 PMID:35380827 NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd40 CD40 molecule decreases expression ISO perfluoroundecanoic acid results in decreased expression of CD40 protein CTD PMID:32916415 NCBI chr 3:174,209,113...174,224,592
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO perfluoroundecanoic acid results in increased expression of CPT1A mRNA CTD PMID:23567314 NCBI chr 1:209,993,881...210,056,329
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Csf1 colony stimulating factor 1 decreases expression ISO perfluoroundecanoic acid results in decreased expression of CSF1 protein CTD PMID:32916415 NCBI chr 2:198,065,400...198,084,774
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Cstb cystatin B decreases expression ISO perfluoroundecanoic acid results in decreased expression of CSTB protein CTD PMID:32916415 NCBI chr20:10,245,157...10,247,199
Ensembl chr20:10,245,462...10,247,526 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression EXP perfluoroundecanoic acid results in decreased expression of CYP11A1 mRNA; perfluoroundecanoic acid results in decreased expression of CYP11A1 protein CTD PMID:33549592 PMID:35143807 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP perfluoroundecanoic acid results in decreased expression of CYP17A1 mRNA; perfluoroundecanoic acid results in decreased expression of CYP17A1 protein CTD PMID:33549592 PMID:35143807 NCBI chr 1:255,476,861...255,484,547
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases expression ISO perfluoroundecanoic acid results in decreased expression of CYP2B10 mRNA CTD PMID:23567314 NCBI chr 1:90,780,468...90,859,852
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO perfluoroundecanoic acid results in decreased expression of CYP7A1 mRNA CTD PMID:23567314 NCBI chr 5:24,174,505...24,184,202
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO perfluoroundecanoic acid results in increased expression of DDIT3 mRNA CTD PMID:23567314 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Dhh desert hedgehog signaling molecule decreases expression EXP perfluoroundecanoic acid results in decreased expression of DHH mRNA; perfluoroundecanoic acid results in decreased expression of DHH protein CTD PMID:33549592 NCBI chr 7:131,929,857...131,935,352
Ensembl chr 7:130,050,910...130,056,406 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 decreases expression ISO perfluoroundecanoic acid results in decreased expression of DKK1 protein CTD PMID:32916415 NCBI chr 1:237,794,969...237,798,650
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions ISO [perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated with perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid] results in increased expression of DRD2 mRNA CTD PMID:34371090 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase increases expression ISO perfluoroundecanoic acid results in increased expression of EHHADH mRNA CTD PMID:35337807 NCBI chr11:92,746,409...92,779,647
Ensembl chr11:79,241,938...79,275,188 		JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO perfluoroundecanoic acid results in increased activity of ESR1 protein CTD PMID:21163906 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fabp1 fatty acid binding protein 1 decreases expression ISO perfluoroundecanoic acid results in decreased expression of FABP1 mRNA CTD PMID:35337807 NCBI chr 4:104,744,302...104,753,119
Ensembl chr 4:103,191,006...103,194,788 		JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO perfluoroundecanoic acid results in decreased expression of FAS protein CTD PMID:32916415 NCBI chr 1:241,212,155...241,245,774
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fasn fatty acid synthase increases expression ISO perfluoroundecanoic acid results in increased expression of FASN mRNA CTD PMID:35337807 NCBI chr10:106,570,415...106,588,581
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression EXP perfluoroundecanoic acid results in decreased expression of FDFT1 mRNA CTD PMID:22071372 NCBI chr15:41,588,114...41,616,168
Ensembl chr15:37,412,146...37,440,287 		JBrowse link
G Fgf23 fibroblast growth factor 23 decreases expression ISO perfluoroundecanoic acid results in decreased expression of FGF23 protein CTD PMID:32916415 NCBI chr 4:161,600,439...161,609,991
Ensembl chr 4:159,914,272...159,923,821 		JBrowse link
G Fshb follicle stimulating hormone subunit beta decreases secretion
decreases expression		 EXP perfluoroundecanoic acid results in decreased secretion of FSHB protein
perfluoroundecanoic acid results in decreased expression of FSHB mRNA		 CTD PMID:33549592 NCBI chr 3:114,003,262...114,007,072
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Fshr follicle stimulating hormone receptor decreases expression EXP perfluoroundecanoic acid results in decreased expression of FSHR mRNA; perfluoroundecanoic acid results in decreased expression of FSHR protein CTD PMID:33549592 NCBI chr 6:10,952,329...11,160,288
Ensembl chr 6:5,198,825...5,406,785 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO perfluoroundecanoic acid results in increased expression of GADD45B mRNA CTD PMID:23567314 NCBI chr 7:9,428,689...9,430,991
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO perfluoroundecanoic acid results in decreased expression of GCLC mRNA CTD PMID:23567314 NCBI chr 8:87,510,251...87,548,896
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gdf15 growth differentiation factor 15 decreases expression ISO perfluoroundecanoic acid results in decreased expression of GDF15 protein CTD PMID:32916415 NCBI chr16:18,838,436...18,842,022
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gnrhr gonadotropin releasing hormone receptor increases expression EXP perfluoroundecanoic acid results in increased expression of GNRHR mRNA CTD PMID:33549592 NCBI chr14:22,211,666...22,229,654
Ensembl chr14:21,856,871...21,874,861 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression ISO perfluoroundecanoic acid results in increased expression of GPAM mRNA CTD PMID:35337807 NCBI chr 1:264,111,599...264,176,112
Ensembl chr 1:254,106,331...254,142,639 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases expression ISO perfluoroundecanoic acid results in decreased expression of GSTA1 mRNA CTD PMID:35337807 NCBI chr 9:31,199,887...31,216,606
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression ISO perfluoroundecanoic acid results in increased expression of GSTM3 mRNA CTD PMID:35337807 NCBI chr 2:198,219,769...198,222,732
Ensembl chr 2:195,531,495...195,534,553 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression
affects expression		 EXP
ISO		 perfluoroundecanoic acid results in decreased expression of HADHA mRNA
perfluoroundecanoic acid affects the expression of HADHA mRNA		 CTD PMID:22071372 PMID:23567314 NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:26,187,956...26,227,869 		JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression EXP perfluoroundecanoic acid results in increased expression of HADHB mRNA CTD PMID:22071372 NCBI chr 6:31,873,404...31,907,557
Ensembl chr 6:26,153,578...26,184,869 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor decreases expression ISO perfluoroundecanoic acid results in decreased expression of HBEGF protein CTD PMID:32916415 NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Hgf hepatocyte growth factor decreases expression ISO perfluoroundecanoic acid results in decreased expression of HGF protein CTD PMID:32916415 NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hhex hematopoietically expressed homeobox increases expression EXP perfluoroundecanoic acid results in increased expression of HHEX mRNA CTD PMID:22071372 NCBI chr 1:244,602,945...244,608,532
Ensembl chr 1:235,190,455...235,196,042 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression
increases expression		 ISO perfluoroundecanoic acid results in decreased expression of HMGCS1 mRNA
perfluoroundecanoic acid results in increased expression of HMGCS1 mRNA		 CTD PMID:23567314 PMID:35337807 NCBI chr 2:53,379,457...53,399,807
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO perfluoroundecanoic acid results in increased expression of HMOX1 mRNA CTD PMID:23567314 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression EXP perfluoroundecanoic acid results in decreased expression of HSD11B1 mRNA; perfluoroundecanoic acid results in decreased expression of HSD11B1 protein CTD PMID:33549592 PMID:35143807 NCBI chr13:107,277,526...107,327,462
Ensembl chr13:104,728,539...104,788,687 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases activity ISO perfluoroundecanoic acid results in decreased activity of HSD11B2 protein CTD PMID:36878351 NCBI chr19:50,307,569...50,312,812
Ensembl chr19:33,397,656...33,402,899 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 decreases expression EXP perfluoroundecanoic acid results in decreased expression of HSD17B3 mRNA; perfluoroundecanoic acid results in decreased expression of HSD17B3 protein CTD PMID:33549592 NCBI chr17:1,032,958...1,064,283
Ensembl chr17:1,027,229...1,058,554 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression
decreases activity		 EXP
ISO		 perfluoroundecanoic acid results in decreased expression of HSD3B1 mRNA; perfluoroundecanoic acid results in decreased expression of HSD3B1 protein
perfluoroundecanoic acid results in decreased activity of HSD3B1 protein		 CTD PMID:33549592 PMID:35143807 PMID:36122607 NCBI chr 2:188,858,574...188,864,694
Ensembl chr 2:186,169,863...186,175,999 		JBrowse link
G Il16 interleukin 16 decreases expression ISO perfluoroundecanoic acid results in decreased expression of IL16 protein CTD PMID:32916415 NCBI chr 1:147,026,852...147,127,177
Ensembl chr 1:137,617,944...137,718,130 		JBrowse link
G Il18 interleukin 18 decreases expression ISO perfluoroundecanoic acid results in decreased expression of IL18 protein CTD PMID:32916415 NCBI chr 8:59,802,072...59,829,275
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il6 interleukin 6 decreases expression ISO perfluoroundecanoic acid results in decreased expression of IL6 protein CTD PMID:32916415 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Insl3 insulin-like 3 decreases expression EXP perfluoroundecanoic acid results in decreased expression of INSL3 mRNA; perfluoroundecanoic acid results in decreased expression of INSL3 protein CTD PMID:33549592 PMID:35143807 NCBI chr16:18,432,668...18,434,539
Ensembl chr16:18,384,829...18,400,560 		JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO perfluoroundecanoic acid inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:42,410,099...42,425,414
Ensembl chr 1:40,004,041...40,019,319 		JBrowse link
G Lhb luteinizing hormone subunit beta decreases secretion
decreases expression		 EXP perfluoroundecanoic acid results in decreased secretion of LHB protein
perfluoroundecanoic acid results in decreased expression of LHB mRNA		 CTD PMID:33549592 NCBI chr 1:105,037,457...105,038,446
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor decreases expression EXP perfluoroundecanoic acid results in decreased expression of LHCGR mRNA; perfluoroundecanoic acid results in decreased expression of LHCGR protein CTD PMID:33549592 NCBI chr 6:11,415,361...11,480,834
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha decreases expression EXP perfluoroundecanoic acid results in decreased expression of MAP1LC3A protein CTD PMID:33549592 NCBI chr 3:164,243,204...164,244,850
Ensembl chr 3:143,783,024...143,784,670 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression EXP perfluoroundecanoic acid results in increased expression of MAP1LC3B protein CTD PMID:33549592 NCBI chr19:66,571,631...66,582,270
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation EXP perfluoroundecanoic acid results in decreased phosphorylation of MAPK1 protein CTD PMID:35143807 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation EXP perfluoroundecanoic acid results in decreased phosphorylation of MAPK3 protein CTD PMID:35143807 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation EXP perfluoroundecanoic acid results in decreased phosphorylation of MTOR protein CTD PMID:33549592 PMID:35143807 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Mttp microsomal triglyceride transfer protein increases expression ISO perfluoroundecanoic acid results in increased expression of MTTP mRNA CTD PMID:35337807 NCBI chr 2:229,286,501...229,327,650
Ensembl chr 2:226,613,090...226,654,239 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases expression ISO perfluoroundecanoic acid results in decreased expression of NFE2L2 mRNA CTD PMID:23567314 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression ISO perfluoroundecanoic acid results in increased expression of NR1I2 mRNA CTD PMID:35337807 NCBI chr11:75,965,717...76,006,733
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 decreases expression EXP perfluoroundecanoic acid results in decreased expression of NR5A1 mRNA; perfluoroundecanoic acid results in decreased expression of NR5A1 protein CTD PMID:33549592 NCBI chr 3:42,874,505...42,896,109
Ensembl chr 3:22,465,502...22,486,328 		JBrowse link
G Pax8 paired box 8 increases expression EXP perfluoroundecanoic acid results in increased expression of PAX8 mRNA CTD PMID:22071372 NCBI chr 3:27,584,000...27,641,094
Ensembl chr 3:7,185,723...7,242,363 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) increases expression ISO perfluoroundecanoic acid results in increased expression of PCK2 mRNA CTD PMID:35337807 NCBI chr15:32,997,853...33,006,691
Ensembl chr15:29,027,894...29,037,283 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO perfluoroundecanoic acid results in increased expression of PDK4 mRNA CTD PMID:23567314 NCBI chr 4:34,558,327...34,568,329
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
G Plin2 perilipin 2 increases expression ISO perfluoroundecanoic acid results in increased expression of PLIN2 mRNA CTD PMID:23567314 NCBI chr 5:106,202,634...106,258,748
Ensembl chr 5:101,154,411...101,242,319 		JBrowse link
G Por cytochrome p450 oxidoreductase increases expression ISO perfluoroundecanoic acid results in increased expression of POR mRNA CTD PMID:23567314 NCBI chr12:26,587,674...26,655,612
Ensembl chr12:20,951,058...20,999,245 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases activity
increases expression		 ISO perfluoroundecanoic acid results in increased activity of PPARA protein
perfluoroundecanoic acid results in increased expression of PPARA mRNA		 CTD PMID:22107727 PMID:35337807 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases expression		 ISO perfluoroundecanoic acid binds to and affects the folding of PPARG protein
perfluoroundecanoic acid results in increased expression of PPARG mRNA		 CTD PMID:24998974 PMID:35337807 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 multiple interactions ISO perfluoroundecanoic acid binds to and results in decreased activity of PTPN11 protein CTD PMID:27572461 NCBI chr12:41,026,079...41,085,577
Ensembl chr12:35,383,144...35,424,925 		JBrowse link
G Retn resistin decreases expression ISO perfluoroundecanoic acid results in decreased expression of RETN protein CTD PMID:32916415 NCBI chr12:6,508,653...6,511,115
Ensembl chr12:1,710,881...1,712,620 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression EXP perfluoroundecanoic acid results in decreased expression of SCARB1 mRNA; perfluoroundecanoic acid results in decreased expression of SCARB1 protein CTD PMID:33549592 PMID:35143807 NCBI chr12:36,957,302...37,023,982
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO perfluoroundecanoic acid results in increased expression of SCD mRNA CTD PMID:35337807 NCBI chr 1:253,218,968...253,232,101
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Serpind1 serpin family D member 1 decreases expression ISO perfluoroundecanoic acid results in decreased expression of SERPIND1 mRNA CTD PMID:23567314 NCBI chr11:97,168,753...97,179,830
Ensembl chr11:83,664,518...83,675,519 		JBrowse link
G Slc25a34 solute carrier family 25, member 34 increases expression ISO perfluoroundecanoic acid results in increased expression of SLC25A34 mRNA CTD PMID:23567314 NCBI chr 5:159,215,120...159,219,892 JBrowse link
G Slc27a1 solute carrier family 27 member 1 increases expression ISO perfluoroundecanoic acid results in increased expression of SLC27A1 mRNA CTD PMID:23567314 NCBI chr16:18,311,859...18,337,024
Ensembl chr16:18,278,984...18,296,063 		JBrowse link
G Sod1 superoxide dismutase 1 decreases expression
increases expression		 EXP
ISO		 perfluoroundecanoic acid results in decreased expression of SOD1 mRNA; perfluoroundecanoic acid results in decreased expression of SOD1 protein
perfluoroundecanoic acid results in increased expression of SOD1 mRNA		 CTD PMID:33549592 PMID:35337807 NCBI chr11:42,942,742...42,948,399
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 decreases expression EXP perfluoroundecanoic acid results in decreased expression of SOD2 mRNA; perfluoroundecanoic acid results in decreased expression of SOD2 protein CTD PMID:33549592 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Spon1 spondin 1 decreases expression ISO perfluoroundecanoic acid results in decreased expression of SPON1 protein CTD PMID:32916415 NCBI chr 1:177,363,526...177,662,689
Ensembl chr 1:167,928,972...168,228,226 		JBrowse link
G Sqstm1 sequestosome 1 decreases expression EXP perfluoroundecanoic acid results in decreased expression of SQSTM1 protein CTD PMID:33549592 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 decreases activity ISO
EXP		 perfluoroundecanoic acid results in decreased activity of SRD5A1 protein CTD PMID:38574835 NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO perfluoroundecanoic acid results in increased expression of SREBF1 mRNA CTD PMID:35337807 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Star steroidogenic acute regulatory protein decreases expression EXP perfluoroundecanoic acid results in decreased expression of STAR mRNA; perfluoroundecanoic acid results in decreased expression of STAR protein CTD PMID:33549592 PMID:35143807 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Sult2a1 sulfotransferase family 2A member 1 increases expression ISO perfluoroundecanoic acid results in increased expression of SULT2A1 mRNA CTD PMID:35337807 NCBI chr 1:84,582,011...84,639,001
Ensembl chr 1:74,911,100...75,508,134 		JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO [perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated with perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid] results in decreased expression of TH mRNA CTD PMID:34371090 NCBI chr 1:207,500,959...207,508,276
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Thra thyroid hormone receptor alpha affects binding ISO perfluoroundecanoic acid binds to THRA protein CTD PMID:24819616 NCBI chr10:84,198,141...84,225,659
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B decreases expression ISO perfluoroundecanoic acid results in decreased expression of TNFRSF1B protein CTD PMID:32916415 NCBI chr 5:162,356,250...162,387,411
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Tnfsf14 TNF superfamily member 14 decreases expression ISO perfluoroundecanoic acid results in decreased expression of TNFSF14 protein CTD PMID:32916415 NCBI chr 9:2,155,270...2,160,100
Ensembl chr 9:2,069,104...2,073,216 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta increases expression EXP perfluoroundecanoic acid results in increased expression of TSHB mRNA CTD PMID:33182161 NCBI chr 2:192,913,171...192,918,054
Ensembl chr 2:190,224,676...190,229,559 		JBrowse link
G Ttr transthyretin multiple interactions ISO perfluoroundecanoic acid affects the reaction [Thyroxine binds to TTR protein] CTD PMID:27528273 NCBI chr18:12,216,684...12,225,972
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
G Tusc3 tumor suppressor candidate 3 multiple interactions ISO [perfluoroundecanoic acid affects the methylation of TUSC3 gene] which affects the expression of TUSC3 mRNA CTD PMID:32653021 NCBI chr16:59,899,642...60,048,813
Ensembl chr16:53,196,195...53,344,781 		JBrowse link
G Txnip thioredoxin interacting protein affects expression ISO perfluoroundecanoic acid affects the expression of TXNIP mRNA CTD PMID:23567314 NCBI chr 2:186,781,933...186,785,736
Ensembl chr 2:184,092,991...184,096,886 		JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression ISO perfluoroundecanoic acid results in decreased expression of VEGFA protein CTD PMID:32916415 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    role 19858
      biological role 19856
        antimicrobial agent 18257
          antifungal agent 17193
            undecanoic acid 104
              1-O-(alpha-D-galactosyl)-N-undecanoylphytosphingosine 0
              1-tridecanoyl-2-undecanoyl-sn-glycero-3-phosphocholine 0
              1-undecanoyl-2-tridecanoyl-sn-glycero-3-phosphocholine 0
              10-methylundecanoic acid 0
              11-hydroxyundecanoic acid + 0
              3-methylundecanoic acid + 0
              N-undecanoylglycine 0
              gamma-undecanolactone 0
              methyl undecanoate 0
              perfluoroundecanoic acid 103
              undecanoyl group 0
              undecanoyl-CoA 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    p-block element atom 19824
                      carbon group element atom 19763
                        carbon atom 19760
                          organic molecular entity 19760
                            heteroorganic entity 19521
                              organochalcogen compound 19282
                                organooxygen compound 19197
                                  carbon oxoacid 18676
                                    carboxylic acid 18673
                                      monocarboxylic acid 18012
                                        fatty acid 16849
                                          saturated fatty acid 16565
                                            straight-chain saturated fatty acid 16099
                                              undecanoic acid 104
                                                1-O-(alpha-D-galactosyl)-N-undecanoylphytosphingosine 0
                                                1-tridecanoyl-2-undecanoyl-sn-glycero-3-phosphocholine 0
                                                1-undecanoyl-2-tridecanoyl-sn-glycero-3-phosphocholine 0
                                                10-methylundecanoic acid 0
                                                11-hydroxyundecanoic acid + 0
                                                3-methylundecanoic acid + 0
                                                N-undecanoylglycine 0
                                                gamma-undecanolactone 0
                                                methyl undecanoate 0
                                                perfluoroundecanoic acid 103
                                                undecanoyl group 0
                                                undecanoyl-CoA 0
paths to the root