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G |
Adh5 |
alcohol dehydrogenase 5 (class III), chi polypeptide |
multiple interactions |
ISO |
undecanoic acid inhibits the reaction [ADH5 protein results in increased reduction of S-Nitrosoglutathione] |
CTD |
PMID:19428350 |
|
NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591
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G |
A2m |
alpha-2-macroglobulin |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of A2M mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of ABCA1 mRNA |
CTD |
PMID:35337807 |
|
NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Acot2 |
acyl-CoA thioesterase 2 |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of ACOT2 mRNA |
CTD |
PMID:35337807 |
|
NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
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G |
Akt1 |
AKT serine/threonine kinase 1 |
decreases phosphorylation |
EXP |
perfluoroundecanoic acid results in decreased phosphorylation of AKT1 protein |
CTD |
PMID:33549592 PMID:35143807 |
|
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Akt2 |
AKT serine/threonine kinase 2 |
decreases phosphorylation |
EXP |
perfluoroundecanoic acid results in decreased phosphorylation of AKT2 protein |
CTD |
PMID:33549592 PMID:35143807 |
|
NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
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G |
Angptl4 |
angiopoietin-like 4 |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of ANGPTL4 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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G |
Apoa2 |
apolipoprotein A2 |
affects expression |
ISO |
perfluoroundecanoic acid affects the expression of APOA2 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
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G |
Apoa4 |
apolipoprotein A4 |
affects expression |
EXP |
perfluoroundecanoic acid affects the expression of APOA4 mRNA |
CTD |
PMID:22071372 |
|
NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
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G |
Atf3 |
activating transcription factor 3 |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of ATF3 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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|
G |
Atp5f1e |
ATP synthase F1 subunit epsilon |
multiple interactions |
ISO |
[perfluoroundecanoic acid affects the methylation of ATP5F1E gene] which affects the expression of ATP5F1E mRNA |
CTD |
PMID:32653021 |
|
NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450
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|
G |
Baat |
bile acid CoA:amino acid N-acyltransferase |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of BAAT mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
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|
G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression |
EXP |
perfluoroundecanoic acid results in increased expression of BAX mRNA; perfluoroundecanoic acid results in increased expression of BAX protein |
CTD |
PMID:33549592 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
decreases expression |
EXP |
perfluoroundecanoic acid results in decreased expression of BCL2 protein |
CTD |
PMID:33549592 |
|
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bdh2 |
3-hydroxybutyrate dehydrogenase 2 |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of BDH2 mRNA |
CTD |
PMID:35337807 |
|
NCBI chr 2:223,702,410...223,723,076
Ensembl chr 2:223,702,412...223,723,072
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|
G |
Becn1 |
beclin 1 |
increases expression |
EXP |
perfluoroundecanoic acid results in increased expression of BECN1 protein |
CTD |
PMID:33549592 |
|
NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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|
G |
Ccl20 |
C-C motif chemokine ligand 20 |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of CCL20 protein |
CTD |
PMID:32916415 |
|
NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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|
G |
Cd36 |
CD36 molecule |
decreases expression increases uptake |
ISO |
perfluoroundecanoic acid results in decreased expression of CD36 mRNA CD36 protein results in increased uptake of perfluoroundecanoic acid |
CTD |
PMID:23567314 PMID:35380827 |
|
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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|
G |
Cd40 |
CD40 molecule |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of CD40 protein |
CTD |
PMID:32916415 |
|
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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|
G |
Cpt1a |
carnitine palmitoyltransferase 1A |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of CPT1A mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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|
G |
Csf1 |
colony stimulating factor 1 |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of CSF1 protein |
CTD |
PMID:32916415 |
|
NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
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G |
Cstb |
cystatin B |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of CSTB protein |
CTD |
PMID:32916415 |
|
NCBI chr20:10,245,462...10,247,505
Ensembl chr20:10,245,462...10,247,526
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|
G |
Cyp11a1 |
cytochrome P450, family 11, subfamily a, polypeptide 1 |
decreases expression |
EXP |
perfluoroundecanoic acid results in decreased expression of CYP11A1 mRNA; perfluoroundecanoic acid results in decreased expression of CYP11A1 protein |
CTD |
PMID:33549592 PMID:35143807 |
|
NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
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|
G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
decreases expression |
EXP |
perfluoroundecanoic acid results in decreased expression of CYP17A1 mRNA; perfluoroundecanoic acid results in decreased expression of CYP17A1 protein |
CTD |
PMID:33549592 PMID:35143807 |
|
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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|
G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of CYP2B10 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of CYP7A1 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of DDIT3 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Dhh |
desert hedgehog signaling molecule |
decreases expression |
EXP |
perfluoroundecanoic acid results in decreased expression of DHH mRNA; perfluoroundecanoic acid results in decreased expression of DHH protein |
CTD |
PMID:33549592 |
|
NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406
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G |
Dkk1 |
dickkopf WNT signaling pathway inhibitor 1 |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of DKK1 protein |
CTD |
PMID:32916415 |
|
NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
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|
G |
Drd2 |
dopamine receptor D2 |
multiple interactions |
ISO |
[perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated with perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid] results in increased expression of DRD2 mRNA |
CTD |
PMID:34371090 |
|
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
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|
G |
Ehhadh |
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of EHHADH mRNA |
CTD |
PMID:35337807 |
|
NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
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|
G |
Esr1 |
estrogen receptor 1 |
increases activity |
ISO |
perfluoroundecanoic acid results in increased activity of ESR1 protein |
CTD |
PMID:21163906 |
|
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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|
G |
Fabp1 |
fatty acid binding protein 1 |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of FABP1 mRNA |
CTD |
PMID:35337807 |
|
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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|
G |
Fas |
Fas cell surface death receptor |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of FAS protein |
CTD |
PMID:32916415 |
|
NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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G |
Fasn |
fatty acid synthase |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of FASN mRNA |
CTD |
PMID:35337807 |
|
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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|
G |
Fdft1 |
farnesyl diphosphate farnesyl transferase 1 |
decreases expression |
EXP |
perfluoroundecanoic acid results in decreased expression of FDFT1 mRNA |
CTD |
PMID:22071372 |
|
NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
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|
G |
Fgf23 |
fibroblast growth factor 23 |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of FGF23 protein |
CTD |
PMID:32916415 |
|
NCBI chr 4:159,914,267...159,923,821
Ensembl chr 4:159,914,272...159,923,821
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|
G |
Fshb |
follicle stimulating hormone subunit beta |
decreases secretion decreases expression |
EXP |
perfluoroundecanoic acid results in decreased secretion of FSHB protein perfluoroundecanoic acid results in decreased expression of FSHB mRNA |
CTD |
PMID:33549592 |
|
NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
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G |
Fshr |
follicle stimulating hormone receptor |
decreases expression |
EXP |
perfluoroundecanoic acid results in decreased expression of FSHR mRNA; perfluoroundecanoic acid results in decreased expression of FSHR protein |
CTD |
PMID:33549592 |
|
NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
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G |
Gadd45b |
growth arrest and DNA-damage-inducible, beta |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of GADD45B mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
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|
G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of GCLC mRNA |
CTD |
PMID:23567314 |
|
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gdf15 |
growth differentiation factor 15 |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of GDF15 protein |
CTD |
PMID:32916415 |
|
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
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G |
Gnrhr |
gonadotropin releasing hormone receptor |
increases expression |
EXP |
perfluoroundecanoic acid results in increased expression of GNRHR mRNA |
CTD |
PMID:33549592 |
|
NCBI chr14:21,856,871...21,874,861
Ensembl chr14:21,856,871...21,874,861
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|
G |
Gpam |
glycerol-3-phosphate acyltransferase, mitochondrial |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of GPAM mRNA |
CTD |
PMID:35337807 |
|
NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
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|
G |
Gsta1 |
glutathione S-transferase alpha 1 |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of GSTA1 mRNA |
CTD |
PMID:35337807 |
|
NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
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|
G |
Gstm5 |
glutathione S-transferase, mu 5 |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of GSTM3 mRNA |
CTD |
PMID:35337807 |
|
NCBI chr 2:195,531,599...195,534,562
Ensembl chr 2:195,531,495...195,534,553
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|
G |
Hadha |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
decreases expression affects expression |
EXP ISO |
perfluoroundecanoic acid results in decreased expression of HADHA mRNA perfluoroundecanoic acid affects the expression of HADHA mRNA |
CTD |
PMID:22071372 PMID:23567314 |
|
NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
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|
G |
Hadhb |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta |
increases expression |
EXP |
perfluoroundecanoic acid results in increased expression of HADHB mRNA |
CTD |
PMID:22071372 |
|
NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
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|
G |
Hbegf |
heparin-binding EGF-like growth factor |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of HBEGF protein |
CTD |
PMID:32916415 |
|
NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
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|
G |
Hgf |
hepatocyte growth factor |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of HGF protein |
CTD |
PMID:32916415 |
|
NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
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|
G |
Hhex |
hematopoietically expressed homeobox |
increases expression |
EXP |
perfluoroundecanoic acid results in increased expression of HHEX mRNA |
CTD |
PMID:22071372 |
|
NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042
|
|
G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
decreases expression increases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of HMGCS1 mRNA perfluoroundecanoic acid results in increased expression of HMGCS1 mRNA |
CTD |
PMID:23567314 PMID:35337807 |
|
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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|
G |
Hmox1 |
heme oxygenase 1 |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of HMOX1 mRNA |
CTD |
PMID:23567314 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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|
G |
Hsd11b1 |
hydroxysteroid 11-beta dehydrogenase 1 |
decreases expression |
EXP |
perfluoroundecanoic acid results in decreased expression of HSD11B1 mRNA; perfluoroundecanoic acid results in decreased expression of HSD11B1 protein |
CTD |
PMID:33549592 PMID:35143807 |
|
NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
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G |
Hsd11b2 |
hydroxysteroid 11-beta dehydrogenase 2 |
decreases activity |
ISO |
perfluoroundecanoic acid results in decreased activity of HSD11B2 protein |
CTD |
PMID:36878351 |
|
NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
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|
G |
Hsd17b3 |
hydroxysteroid (17-beta) dehydrogenase 3 |
decreases expression |
EXP |
perfluoroundecanoic acid results in decreased expression of HSD17B3 mRNA; perfluoroundecanoic acid results in decreased expression of HSD17B3 protein |
CTD |
PMID:33549592 |
|
NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554
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|
G |
Hsd3b1 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
decreases expression decreases activity |
EXP ISO |
perfluoroundecanoic acid results in decreased expression of HSD3B1 mRNA; perfluoroundecanoic acid results in decreased expression of HSD3B1 protein perfluoroundecanoic acid results in decreased activity of HSD3B1 protein |
CTD |
PMID:33549592 PMID:35143807 PMID:36122607 |
|
NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
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|
G |
Il16 |
interleukin 16 |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of IL16 protein |
CTD |
PMID:32916415 |
|
NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130
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|
G |
Il18 |
interleukin 18 |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of IL18 protein |
CTD |
PMID:32916415 |
|
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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|
G |
Il6 |
interleukin 6 |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of IL6 protein |
CTD |
PMID:32916415 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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|
G |
Insl3 |
insulin-like 3 |
decreases expression |
EXP |
perfluoroundecanoic acid results in decreased expression of INSL3 mRNA; perfluoroundecanoic acid results in decreased expression of INSL3 protein |
CTD |
PMID:33549592 PMID:35143807 |
|
NCBI chr16:18,398,682...18,400,566
Ensembl chr16:18,384,829...18,400,560
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|
G |
Iyd |
iodotyrosine deiodinase |
multiple interactions |
ISO |
perfluoroundecanoic acid inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] |
CTD |
PMID:33352258 |
|
NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
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|
G |
Lhb |
luteinizing hormone subunit beta |
decreases secretion decreases expression |
EXP |
perfluoroundecanoic acid results in decreased secretion of LHB protein perfluoroundecanoic acid results in decreased expression of LHB mRNA |
CTD |
PMID:33549592 |
|
NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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|
G |
Lhcgr |
luteinizing hormone/choriogonadotropin receptor |
decreases expression |
EXP |
perfluoroundecanoic acid results in decreased expression of LHCGR mRNA; perfluoroundecanoic acid results in decreased expression of LHCGR protein |
CTD |
PMID:33549592 |
|
NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
|
|
G |
Map1lc3a |
microtubule-associated protein 1 light chain 3 alpha |
decreases expression |
EXP |
perfluoroundecanoic acid results in decreased expression of MAP1LC3A protein |
CTD |
PMID:33549592 |
|
NCBI chr 3:143,783,024...143,784,670
Ensembl chr 3:143,783,024...143,784,670
|
|
G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
increases expression |
EXP |
perfluoroundecanoic acid results in increased expression of MAP1LC3B protein |
CTD |
PMID:33549592 |
|
NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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|
G |
Mapk1 |
mitogen activated protein kinase 1 |
decreases phosphorylation |
EXP |
perfluoroundecanoic acid results in decreased phosphorylation of MAPK1 protein |
CTD |
PMID:35143807 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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|
G |
Mapk3 |
mitogen activated protein kinase 3 |
decreases phosphorylation |
EXP |
perfluoroundecanoic acid results in decreased phosphorylation of MAPK3 protein |
CTD |
PMID:35143807 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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|
G |
Mtor |
mechanistic target of rapamycin kinase |
decreases phosphorylation |
EXP |
perfluoroundecanoic acid results in decreased phosphorylation of MTOR protein |
CTD |
PMID:33549592 PMID:35143807 |
|
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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|
G |
Mttp |
microsomal triglyceride transfer protein |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of MTTP mRNA |
CTD |
PMID:35337807 |
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NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
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Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of NFE2L2 mRNA |
CTD |
PMID:23567314 |
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of NR1I2 mRNA |
CTD |
PMID:35337807 |
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NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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Nr5a1 |
nuclear receptor subfamily 5, group A, member 1 |
decreases expression |
EXP |
perfluoroundecanoic acid results in decreased expression of NR5A1 mRNA; perfluoroundecanoic acid results in decreased expression of NR5A1 protein |
CTD |
PMID:33549592 |
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NCBI chr 3:22,464,786...22,486,328
Ensembl chr 3:22,465,502...22,486,328
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Pax8 |
paired box 8 |
increases expression |
EXP |
perfluoroundecanoic acid results in increased expression of PAX8 mRNA |
CTD |
PMID:22071372 |
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NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
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Pck2 |
phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of PCK2 mRNA |
CTD |
PMID:35337807 |
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NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
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Pdk4 |
pyruvate dehydrogenase kinase 4 |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of PDK4 mRNA |
CTD |
PMID:23567314 |
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NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
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Plin2 |
perilipin 2 |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of PLIN2 mRNA |
CTD |
PMID:23567314 |
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NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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Por |
cytochrome p450 oxidoreductase |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of POR mRNA |
CTD |
PMID:23567314 |
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NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
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Ppara |
peroxisome proliferator activated receptor alpha |
increases activity increases expression |
ISO |
perfluoroundecanoic acid results in increased activity of PPARA protein perfluoroundecanoic acid results in increased expression of PPARA mRNA |
CTD |
PMID:22107727 PMID:35337807 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions increases expression |
ISO |
perfluoroundecanoic acid binds to and affects the folding of PPARG protein perfluoroundecanoic acid results in increased expression of PPARG mRNA |
CTD |
PMID:24998974 PMID:35337807 |
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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Ptpn11 |
protein tyrosine phosphatase, non-receptor type 11 |
multiple interactions |
ISO |
perfluoroundecanoic acid binds to and results in decreased activity of PTPN11 protein |
CTD |
PMID:27572461 |
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NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
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Retn |
resistin |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of RETN protein |
CTD |
PMID:32916415 |
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NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
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Scarb1 |
scavenger receptor class B, member 1 |
decreases expression |
EXP |
perfluoroundecanoic acid results in decreased expression of SCARB1 mRNA; perfluoroundecanoic acid results in decreased expression of SCARB1 protein |
CTD |
PMID:33549592 PMID:35143807 |
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NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
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Scd |
stearoyl-CoA desaturase |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of SCD mRNA |
CTD |
PMID:35337807 |
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NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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Serpind1 |
serpin family D member 1 |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of SERPIND1 mRNA |
CTD |
PMID:23567314 |
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NCBI chr11:83,664,517...83,675,593
Ensembl chr11:83,664,518...83,675,519
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Slc25a34 |
solute carrier family 25, member 34 |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of SLC25A34 mRNA |
CTD |
PMID:23567314 |
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NCBI chr 5:153,932,081...153,936,854
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Slc27a1 |
solute carrier family 27 member 1 |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of SLC27A1 mRNA |
CTD |
PMID:23567314 |
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NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
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Sod1 |
superoxide dismutase 1 |
decreases expression increases expression |
EXP ISO |
perfluoroundecanoic acid results in decreased expression of SOD1 mRNA; perfluoroundecanoic acid results in decreased expression of SOD1 protein perfluoroundecanoic acid results in increased expression of SOD1 mRNA |
CTD |
PMID:33549592 PMID:35337807 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Sod2 |
superoxide dismutase 2 |
decreases expression |
EXP |
perfluoroundecanoic acid results in decreased expression of SOD2 mRNA; perfluoroundecanoic acid results in decreased expression of SOD2 protein |
CTD |
PMID:33549592 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Spon1 |
spondin 1 |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of SPON1 protein |
CTD |
PMID:32916415 |
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NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226
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Sqstm1 |
sequestosome 1 |
decreases expression |
EXP |
perfluoroundecanoic acid results in decreased expression of SQSTM1 protein |
CTD |
PMID:33549592 |
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NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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Srebf1 |
sterol regulatory element binding transcription factor 1 |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of SREBF1 mRNA |
CTD |
PMID:35337807 |
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NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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Star |
steroidogenic acute regulatory protein |
decreases expression |
EXP |
perfluoroundecanoic acid results in decreased expression of STAR mRNA; perfluoroundecanoic acid results in decreased expression of STAR protein |
CTD |
PMID:33549592 PMID:35143807 |
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NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
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Sult2a1 |
sulfotransferase family 2A member 1 |
increases expression |
ISO |
perfluoroundecanoic acid results in increased expression of SULT2A1 mRNA |
CTD |
PMID:35337807 |
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NCBI chr 1:75,451,178...75,508,113
Ensembl chr 1:74,911,100...75,508,134
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Th |
tyrosine hydroxylase |
multiple interactions |
ISO |
[perfluoro-n-nonanoic acid co-treated with perfluorodecanoic acid co-treated with perfluoroundecanoic acid co-treated with perfluorododecanoic acid co-treated with perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid] results in decreased expression of TH mRNA |
CTD |
PMID:34371090 |
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NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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Thra |
thyroid hormone receptor alpha |
affects binding |
ISO |
perfluoroundecanoic acid binds to THRA protein |
CTD |
PMID:24819616 |
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NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
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Tnfrsf1b |
TNF receptor superfamily member 1B |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of TNFRSF1B protein |
CTD |
PMID:32916415 |
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NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
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Tnfsf14 |
TNF superfamily member 14 |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of TNFSF14 protein |
CTD |
PMID:32916415 |
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NCBI chr 9:2,068,295...2,073,128
Ensembl chr 9:2,069,104...2,073,216
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Tshb |
thyroid stimulating hormone subunit beta |
increases expression |
EXP |
perfluoroundecanoic acid results in increased expression of TSHB mRNA |
CTD |
PMID:33182161 |
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NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
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Ttr |
transthyretin |
multiple interactions |
ISO |
perfluoroundecanoic acid affects the reaction [Thyroxine binds to TTR protein] |
CTD |
PMID:27528273 |
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NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
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Tusc3 |
tumor suppressor candidate 3 |
multiple interactions |
ISO |
[perfluoroundecanoic acid affects the methylation of TUSC3 gene] which affects the expression of TUSC3 mRNA |
CTD |
PMID:32653021 |
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NCBI chr16:53,196,195...53,345,241
Ensembl chr16:53,196,195...53,344,781
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Txnip |
thioredoxin interacting protein |
affects expression |
ISO |
perfluoroundecanoic acid affects the expression of TXNIP mRNA |
CTD |
PMID:23567314 |
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NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
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Vegfa |
vascular endothelial growth factor A |
decreases expression |
ISO |
perfluoroundecanoic acid results in decreased expression of VEGFA protein |
CTD |
PMID:32916415 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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