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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:perfluoroundecanoic acid
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Accession:CHEBI:83493 term browser browse the term
Definition:A fluoroalkanoic acid that is perfluorinated undecanoic acid.
Synonyms:exact_synonym: henicosafluoroundecanoic acid
 related_synonym: Formula=C11HF21O2;   InChI=1S/C11HF21O2/c12-2(13,1(33)34)3(14,15)4(16,17)5(18,19)6(20,21)7(22,23)8(24,25)9(26,27)10(28,29)11(30,31)32/h(H,33,34);   InChIKey=SIDINRCMMRKXGQ-UHFFFAOYSA-N;   SMILES=OC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F
 xref: CAS:2058-94-8
 xref_mesh: MESH:C101814
 xref: PMID:24418714;   PMID:24486970;   PMID:24952613;   Reaxys:2318888


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perfluoroundecanoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression ISO perfluoro-n-undecanoic acid results in decreased expression of A2M mRNA CTD PMID:23567314 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO perfluoro-n-undecanoic acid results in increased expression of ANGPTL4 mRNA CTD PMID:23567314 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Apoa2 apolipoprotein A2 affects expression ISO perfluoro-n-undecanoic acid affects the expression of APOA2 mRNA CTD PMID:23567314 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355
JBrowse link
G Apoa4 apolipoprotein A4 affects expression EXP perfluoroundecanoic acid affects the expression of APOA4 mRNA CTD PMID:22071372 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO perfluoro-n-undecanoic acid results in increased expression of ATF3 mRNA CTD PMID:23567314 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon multiple interactions ISO [perfluoroundecanoic acid affects the methylation of ATP5E gene] which affects the expression of ATP5E mRNA CTD PMID:32653021 NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase decreases expression ISO perfluoro-n-undecanoic acid results in decreased expression of BAAT mRNA CTD PMID:23567314 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
JBrowse link
G Cd36 CD36 molecule decreases expression ISO perfluoro-n-undecanoic acid results in decreased expression of CD36 mRNA CTD PMID:23567314 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO perfluoro-n-undecanoic acid results in increased expression of CPT1A mRNA CTD PMID:23567314 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases expression ISO perfluoro-n-undecanoic acid results in decreased expression of CYP2B10 mRNA CTD PMID:23567314 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO perfluoro-n-undecanoic acid results in decreased expression of CYP7A1 mRNA CTD PMID:23567314 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO perfluoro-n-undecanoic acid results in increased expression of DDIT3 mRNA CTD PMID:23567314 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO perfluoro-n-undecanoic acid results in increased activity of ESR1 protein CTD PMID:21163906 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression EXP perfluoroundecanoic acid results in decreased expression of FDFT1 mRNA CTD PMID:22071372 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO perfluoro-n-undecanoic acid results in increased expression of GADD45B mRNA CTD PMID:23567314 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression ISO perfluoro-n-undecanoic acid results in decreased expression of GCLC mRNA CTD PMID:23567314 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha affects expression
decreases expression
ISO
EXP
perfluoro-n-undecanoic acid affects the expression of HADHA mRNA
perfluoroundecanoic acid results in decreased expression of HADHA mRNA
CTD PMID:22071372 PMID:23567314 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression EXP perfluoroundecanoic acid results in increased expression of HADHB mRNA CTD PMID:22071372 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
JBrowse link
G Hhex hematopoietically expressed homeobox increases expression EXP perfluoroundecanoic acid results in increased expression of HHEX mRNA CTD PMID:22071372 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO perfluoro-n-undecanoic acid results in decreased expression of HMGCS1 mRNA CTD PMID:23567314 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO perfluoro-n-undecanoic acid results in increased expression of HMOX1 mRNA CTD PMID:23567314 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO perfluoroundecanoic acid inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 decreases expression ISO perfluoro-n-undecanoic acid results in decreased expression of NFE2L2 mRNA CTD PMID:23567314 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Pax8 paired box 8 increases expression EXP perfluoroundecanoic acid results in increased expression of PAX8 mRNA CTD PMID:22071372 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO perfluoro-n-undecanoic acid results in increased expression of PDK4 mRNA CTD PMID:23567314 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Plin2 perilipin 2 increases expression ISO perfluoro-n-undecanoic acid results in increased expression of PLIN2 mRNA CTD PMID:23567314 NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression ISO perfluoro-n-undecanoic acid results in increased expression of POR mRNA CTD PMID:23567314 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases activity ISO perfluoro-n-undecanoic acid results in increased activity of PPARA protein CTD PMID:22107727 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO perfluoroundecanoic acid binds to and affects the folding of PPARG protein CTD PMID:24998974 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 multiple interactions ISO perfluoroundecanoic acid binds to and results in decreased activity of PTPN11 protein CTD PMID:27572461 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
JBrowse link
G Serpind1 serpin family D member 1 decreases expression ISO perfluoro-n-undecanoic acid results in decreased expression of SERPIND1 mRNA CTD PMID:23567314 NCBI chr11:83,664,517...83,675,593
Ensembl chr11:83,664,518...83,675,519
JBrowse link
G Slc25a34 solute carrier family 25, member 34 increases expression ISO perfluoro-n-undecanoic acid results in increased expression of SLC25A34 mRNA CTD PMID:23567314 NCBI chr 5:153,932,081...153,936,854 JBrowse link
G Slc27a1 solute carrier family 27 member 1 increases expression ISO perfluoro-n-undecanoic acid results in increased expression of SLC27A1 mRNA CTD PMID:23567314 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Thra thyroid hormone receptor alpha affects binding ISO perfluoroundecanoic acid binds to THRA protein CTD PMID:24819616 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Ttr transthyretin multiple interactions ISO perfluoroundecanoic acid affects the reaction [Thyroxine binds to TTR protein] CTD PMID:27528273 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
JBrowse link
G Tusc3 tumor suppressor candidate 3 multiple interactions ISO [perfluoroundecanoic acid affects the methylation of TUSC3 gene] which affects the expression of TUSC3 mRNA CTD PMID:32653021 NCBI chr16:53,196,195...53,345,241
Ensembl chr16:53,196,195...53,344,781
JBrowse link
G Txnip thioredoxin interacting protein affects expression ISO perfluoro-n-undecanoic acid affects the expression of TXNIP mRNA CTD PMID:23567314 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link

Term paths to the root
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  CHEBI ontology 19812
    role 19761
      biological role 19761
        xenobiotic 18442
          perfluoroundecanoic acid 37
Path 2
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  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic group 18728
                              organic divalent group 18719
                                organodiyl group 18719
                                  carbonyl group 18667
                                    carbonyl compound 18667
                                      carboxylic acid 18364
                                        monocarboxylic acid 17632
                                          fatty acid 16012
                                            saturated fatty acid 15986
                                              straight-chain saturated fatty acid 15442
                                                undecanoic acid 37
                                                  perfluoroundecanoic acid 37
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