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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:Hedgehog signaling pathway
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Accession:PW:0000122 term browser browse the term
Definition:The Hedgehog signaling pathway (Hh) plays important roles in vertebrate embryogenesis, particularly in the differentiation of the neural tube, in vasculogenesis and in angiogenesis. Post-embryonically it is believed to play a homeostatic role in the maintenance of stem cells. Alteration of the pathway has been implicated in a number of human cancers.
Synonyms:related_synonym: Signaling by Hedgehog;   smoothened signaling pathway
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show annotations for term's descendants           Sort by:
Hedgehog signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO PID PID:200168 PID:200172 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Arrb2 arrestin, beta 2 ISO PID PID:200168 PID:200172 NCBI chr10:55,146,887...55,154,854
Ensembl chr10:55,146,818...55,154,850 		JBrowse link
G Bmp2 bone morphogenetic protein 2 IEA KEGG rno:04340 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp4 bone morphogenetic protein 4 IEA KEGG rno:04340 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmp5 bone morphogenetic protein 5 IEA KEGG rno:04340 NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:76,517,164...76,639,925 		JBrowse link
G Bmp6 bone morphogenetic protein 6 IEA KEGG rno:04340 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Bmp7 bone morphogenetic protein 7 IEA KEGG rno:04340 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Bmp8a bone morphogenetic protein 8a IEA KEGG rno:04340 NCBI chr 5:135,589,839...135,617,785
Ensembl chr 5:135,591,716...135,617,785 		JBrowse link
G Boc BOC cell adhesion associated, oncogene regulated ISO RGD PMID:20844013 RGD:5510025 NCBI chr11:56,122,697...56,198,060
Ensembl chr11:56,122,750...56,198,059 		JBrowse link
G Btrc beta-transducin repeat containing E3 ubiquitin protein ligase ISO
IEA		 KEGG
RGD		 PMID:20635334 rno:04340, RGD:5510026 NCBI chr 1:244,210,299...244,380,126
Ensembl chr 1:244,210,314...244,376,721 		JBrowse link
G Cdon cell adhesion associated, oncogene regulated ISO PID
RGD		 PMID:20844013 PID:200168, RGD:5510025 NCBI chr 8:33,775,123...33,861,635
Ensembl chr 8:33,806,183...33,859,033 		JBrowse link
G Crebbp CREB binding protein ISO PID PID:200172 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Csnk1a1 casein kinase 1, alpha 1 ISO
IEA		 PID
KEGG		 PID:200172 rno:04340 NCBI chr18:55,017,049...55,050,184
Ensembl chr18:55,017,055...55,049,271 		JBrowse link
G Csnk1d casein kinase 1, delta ISO
IEA		 PID
KEGG		 PID:200172 rno:04340 NCBI chr10:106,221,992...106,256,620
Ensembl chr10:106,221,992...106,256,614 		JBrowse link
G Csnk1e casein kinase 1, epsilon ISO
IEA		 PID
KEGG		 PID:200172 rno:04340 NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794 		JBrowse link
G Csnk1g1 casein kinase 1, gamma 1 ISO
IEA		 PID
KEGG		 PID:200172 rno:04340 NCBI chr 8:66,439,760...66,577,247
Ensembl chr 8:66,439,864...66,572,826 		JBrowse link
G Csnk1g2 casein kinase 1, gamma 2 ISO
IEA		 PID
KEGG		 PID:200172 rno:04340 NCBI chr 7:9,076,739...9,095,082
Ensembl chr 7:9,076,740...9,095,052 		JBrowse link
G Csnk1g3 casein kinase 1, gamma 3 ISO
IEA		 PID
KEGG		 PID:200172 rno:04340 NCBI chr18:47,299,547...47,386,538
Ensembl chr18:47,299,579...47,386,535 		JBrowse link
G Dhh desert hedgehog signaling molecule IMP
IEA
ISO		 KEGG
PID
RGD		 PMID:11118005 PMID:20844013 PMID:20716670 PID:200168 rno:04340, RGD:634737, RGD:5510025, RGD:5510013 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406 		JBrowse link
G Disp1 dispatched RND transporter family member 1 ISO RGD PMID:20635334 RGD:5510026 NCBI chr13:94,720,928...94,866,695
Ensembl chr13:94,720,928...94,866,702 		JBrowse link
G Fbxw11 F-box and WD repeat domain containing 11 ISO
IEA		 PID
KEGG		 PID:200172 rno:04340 NCBI chr10:17,232,735...17,330,574
Ensembl chr10:17,227,181...17,330,571 		JBrowse link
G Foxa2 forkhead box A2 ISO PID PID:200172 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326 		JBrowse link
G Gas1 growth arrest-specific 1 ISO PID
RGD		 PMID:20844013 PID:200168 RGD:5510025 NCBI chr17:4,482,168...4,485,153 JBrowse link
G Gli1 GLI family zinc finger 1 ISO
IEA		 KEGG
PID
RGD		 PMID:20716670 PMID:20635334 PID:200172 rno:04340, RGD:5510013, RGD:5510026 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251 		JBrowse link
G Gli2 GLI family zinc finger 2 ISO
IEA		 KEGG
PID
RGD		 PMID:20716670 PMID:20635334 PID:200168 PID:200172 rno:04340, RGD:5510013, RGD:5510026 NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Gli3 GLI family zinc finger 3 TAS
IEA
ISO		 KEGG
PID
RGD		 PMID:15328011 PMID:20635334 PMID:20716670 PID:200172 rno:04340, RGD:1303367, RGD:5510026, RGD:5510013 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Gnai1 G protein subunit alpha i1 ISO PID PID:200172 NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417 		JBrowse link
G Gnai2 G protein subunit alpha i2 ISO PID PID:200172 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gnai3 G protein subunit alpha i3 ISO PID PID:200172 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742 		JBrowse link
G Gnao1 G protein subunit alpha o1 ISO PID PID:200172 NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493 		JBrowse link
G Gnaz G protein subunit alpha z ISO PID PID:200172 NCBI chr20:13,643,473...13,694,240
Ensembl chr20:13,644,640...13,669,907 		JBrowse link
G Gnb1 G protein subunit beta 1 ISO PID PID:200172 NCBI chr 5:166,075,508...166,142,223
Ensembl chr 5:166,075,629...166,142,124 		JBrowse link
G Gng2 G protein subunit gamma 2 ISO PID PID:200172 NCBI chr15:4,316,038...4,416,918
Ensembl chr15:4,316,059...4,417,183 		JBrowse link
G Gpc1 glypican 1 ISO RGD PMID:20231458 RGD:5510027 NCBI chr 9:93,396,234...93,424,047
Ensembl chr 9:93,396,234...93,424,047 		JBrowse link
G Gpc2 glypican 2 IMP RGD PMID:20231458 RGD:5510027 NCBI chr12:17,277,875...17,284,297
Ensembl chr12:17,277,875...17,284,208 		JBrowse link
G Gpc3 glypican 3 ISO RGD PMID:20231458 RGD:5510027 NCBI chr  X:131,868,986...132,236,824
Ensembl chr  X:131,868,990...132,236,798 		JBrowse link
G Gpc4 glypican 4 ISO RGD PMID:20231458 RGD:5510027 NCBI chr  X:131,644,711...131,755,349
Ensembl chr  X:131,644,704...131,755,284 		JBrowse link
G Gpc5 glypican 5 ISO RGD PMID:20231458 RGD:5510027 NCBI chr15:92,207,275...93,644,054
Ensembl chr15:92,239,176...93,643,282 		JBrowse link
G Gpc6 glypican 6 ISO RGD PMID:20231458 RGD:5510027 NCBI chr15:94,030,218...95,027,883
Ensembl chr15:94,029,884...95,024,006 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 ISO PID PID:200168 NCBI chr 1:201,580,823...201,601,580
Ensembl chr 1:201,581,480...201,601,582 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO
IEA		 KEGG
PID
RGD		 PMID:20635334 PID:200172 rno:04340, RGD:5510026 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hdac1 histone deacetylase 1 ISO PID PID:200172 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hdac2 histone deacetylase 2 ISO PID PID:200172 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Hhat hedgehog acyltransferase ISO PID PID:200168 NCBI chr13:104,024,507...104,283,580
Ensembl chr13:104,010,916...104,282,893 		JBrowse link
G Hhip Hedgehog-interacting protein ISO
IEA		 KEGG
PID
RGD		 PMID:20844013 PID:200168 rno:04340, RGD:5510025 NCBI chr19:27,863,684...27,952,528
Ensembl chr19:27,863,213...27,952,528 		JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 IDA RGD PMID:21720682 RGD:5510033 NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594 		JBrowse link
G Ift172 intraflagellar transport 172 ISO PID PID:200172 NCBI chr 6:25,081,933...25,121,271
Ensembl chr 6:25,081,980...25,120,860 		JBrowse link
G Ift88 intraflagellar transport 88 ISO PID PID:200172 NCBI chr15:31,573,325...31,666,068
Ensembl chr15:31,573,376...31,672,147 		JBrowse link
G Ihh Indian hedgehog signaling molecule ISO
IEA		 KEGG
PID
RGD		 PMID:20716670 PMID:12082161 PMID:20844013 PID:200168 rno:04340, RGD:5510013, RGD:1299259, RGD:5510025 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Kif3a kinesin family member 3a ISO PID PID:200172 NCBI chr10:37,725,930...37,761,183
Ensembl chr10:37,725,970...37,759,191 		JBrowse link
G Lgals3 galectin 3 ISO PID PID:200172 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
G Lrp2 LDL receptor related protein 2 ISO
IEA		 KEGG
PID
RGD		 PMID:20635334 PID:200168 rno:04340, RGD:5510026 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708 		JBrowse link
G Lrpap1 LDL receptor related protein associated protein 1 ISO PID PID:200168 NCBI chr14:75,651,371...75,663,380
Ensembl chr14:75,651,376...75,665,414 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 ISO PID PID:200172 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 ISO PID PID:200172 NCBI chr 7:90,488,751...90,628,007
Ensembl chr 7:90,488,754...90,627,968 		JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 ISO PID PID:200172 NCBI chr 8:63,338,150...63,451,670
Ensembl chr 8:63,338,150...63,438,905 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha ISO PID PID:200168 NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 ISO PID PID:200168 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha ISO
IEA		 PID
KEGG		 PID:200172 rno:04340 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta IEA KEGG rno:04340 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198 		JBrowse link
G Prkcd protein kinase C, delta ISO PID PID:200172 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prkx protein kinase cAMP-dependent X-linked catalytic subunit IEA KEGG rno:04340 NCBI chr  X:41,823,349...41,866,844
Ensembl chr  X:41,823,355...41,866,669 		JBrowse link
G Ptch1 patched 1 ISS
IEA
ISO		 KEGG
PID
RGD		 PMID:9422511 PMID:20635334 PMID:20716670 PID:200168 PID:200172 rno:04340, RGD:704355, RGD:5510026, RGD:5510013 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Ptch2 patched 2 ISO PID
RGD		 PMID:20635334 PMID:20716670 PID:200168 RGD:5510013 RGD:5510026 NCBI chr 5:130,571,956...130,592,506
Ensembl chr 5:130,572,312...130,592,405 		JBrowse link
G Pthlh parathyroid hormone-like hormone ISO PID PID:200168 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847 		JBrowse link
G Rab23 RAB23, member RAS oncogene family ISO
IEA		 PID
KEGG		 PID:200172 rno:04340 NCBI chr 9:35,943,522...35,967,367
Ensembl chr 9:35,944,085...35,966,927 		JBrowse link
G Rbbp4 RB binding protein 4, chromatin remodeling factor ISO PID PID:200172 NCBI chr 5:141,655,863...141,675,157
Ensembl chr 5:141,638,421...141,675,284 		JBrowse link
G Rbbp7 RB binding protein 7, chromatin remodeling factor ISO PID PID:200172 NCBI chr  X:31,913,080...31,931,245
Ensembl chr  X:31,913,081...31,931,226 		JBrowse link
G Sap18 Sin3A associated protein 18 ISO PID PID:200172 NCBI chr15:31,943,228...31,947,534
Ensembl chr15:31,943,230...31,950,038
Ensembl chr10:31,943,230...31,950,038 		JBrowse link
G Sap30 Sin3A associated protein 30 ISO PID PID:200172 NCBI chr16:32,747,777...32,753,114
Ensembl chr16:32,747,734...32,753,112 		JBrowse link
G Shh sonic hedgehog signaling molecule ISO
IEA		 KEGG
PID
RGD		 PMID:20716670 PMID:12417650 PMID:20844013 PID:200168 PID:200172 rno:04340, RGD:5510013, RGD:628387, RGD:5510025 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Sin3a SIN3 transcription regulator family member A ISO PID PID:200172 NCBI chr 8:57,481,539...57,536,195
Ensembl chr 8:57,481,573...57,536,192 		JBrowse link
G Sin3b SIN3 transcription regulator family member B ISO PID PID:200172 NCBI chr16:17,123,277...17,159,978
Ensembl chr16:17,123,434...17,159,978 		JBrowse link
G Smo smoothened, frizzled class receptor ISO
IEA		 KEGG
PID
RGD		 PMID:20716670 PMID:9422511 PMID:20635334 PID:200168 PID:200172 rno:04340, RGD:5510013, RGD:704355, RGD:5510026 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Spop speckle type BTB/POZ protein ISO PID PID:200172 NCBI chr10:80,358,121...80,438,983
Ensembl chr10:80,358,124...80,483,955 		JBrowse link
G Sspo SCO-spondin ISO PID PID:200172 NCBI chr 4:77,394,915...77,450,526
Ensembl chr 4:77,397,059...77,450,412 		JBrowse link
G Stil STIL, centriolar assembly protein ISO PID PID:200168 NCBI chr 5:128,520,837...128,573,732
Ensembl chr 5:128,520,953...128,573,730 		JBrowse link
G Stk36 serine/threonine kinase 36 ISO
IEA		 PID
KEGG		 PID:200172 rno:04340 NCBI chr 9:76,176,922...76,204,423
Ensembl chr 9:76,176,920...76,204,422 		JBrowse link
G Sufu SUFU negative regulator of hedgehog signaling ISO
IEA		 KEGG
PID
RGD		 PMID:20716670 PID:200172 rno:04340, RGD:5510013 NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO PID PID:200168 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Wnt1 Wnt family member 1 IEA KEGG rno:04340 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
G Wnt10a Wnt family member 10A IEA KEGG rno:04340 NCBI chr 9:76,349,931...76,362,400
Ensembl chr 9:76,349,931...76,362,400 		JBrowse link
G Wnt10b Wnt family member 10B IEA KEGG rno:04340 NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892 		JBrowse link
G Wnt11 Wnt family member 11 IEA KEGG rno:04340 NCBI chr 1:153,134,503...153,154,294
Ensembl chr 1:153,138,197...153,154,294 		JBrowse link
G Wnt16 Wnt family member 16 IEA KEGG rno:04340 NCBI chr 4:50,820,968...50,831,380
Ensembl chr 4:50,820,968...50,831,380 		JBrowse link
G Wnt2 Wnt family member 2 IEA KEGG rno:04340 NCBI chr 4:46,328,408...46,374,673
Ensembl chr 4:46,333,998...46,374,402 		JBrowse link
G Wnt2b Wnt family member 2B IEA KEGG rno:04340 NCBI chr 2:192,454,226...192,468,599
Ensembl chr 2:192,453,824...192,470,308 		JBrowse link
G Wnt3 Wnt family member 3 IEA KEGG rno:04340 NCBI chr10:88,680,198...88,724,170
Ensembl chr10:88,680,248...88,724,099 		JBrowse link
G Wnt3a Wnt family member 3A IEA KEGG rno:04340 NCBI chr10:44,034,174...44,078,366
Ensembl chr10:44,034,194...44,078,324 		JBrowse link
G Wnt4 Wnt family member 4 IEA KEGG rno:04340 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
G Wnt5a Wnt family member 5A IEA KEGG rno:04340 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G Wnt5b Wnt family member 5B IEA KEGG rno:04340 NCBI chr 4:152,609,566...152,733,790
Ensembl chr 4:152,609,569...152,733,407 		JBrowse link
G Wnt6 Wnt family member 6 IEA KEGG rno:04340 NCBI chr 9:76,329,882...76,343,523
Ensembl chr 9:76,329,882...76,343,523 		JBrowse link
G Wnt7a Wnt family member 7A IEA KEGG rno:04340 NCBI chr 4:123,863,108...123,908,981
Ensembl chr 4:123,863,108...123,908,981 		JBrowse link
G Wnt7b Wnt family member 7B IEA KEGG rno:04340 NCBI chr 7:116,634,817...116,679,459
Ensembl chr 7:116,634,814...116,679,581 		JBrowse link
G Wnt8a Wnt family member 8A IEA KEGG rno:04340 NCBI chr18:26,137,690...26,143,283
Ensembl chr18:26,137,690...26,143,283 		JBrowse link
G Wnt8b Wnt family member 8B IEA KEGG rno:04340 NCBI chr 1:243,354,145...243,376,000
Ensembl chr 1:243,354,086...243,374,286 		JBrowse link
G Wnt9a Wnt family member 9A IEA KEGG rno:04340 NCBI chr10:44,094,140...44,121,134
Ensembl chr10:44,094,140...44,121,133 		JBrowse link
G Wnt9b Wnt family member 9B IEA KEGG rno:04340 NCBI chr10:88,635,330...88,657,035
Ensembl chr10:88,635,331...88,657,035 		JBrowse link
G Xpo1 exportin 1 ISO PID PID:200172 NCBI chr14:97,233,282...97,275,536
Ensembl chr14:97,233,270...97,275,498 		JBrowse link
G Zic2 Zic family member 2 IEA KEGG rno:04340 NCBI chr15:99,576,697...99,581,522
Ensembl chr15:99,576,697...99,581,522 		JBrowse link
altered Hedgehog signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Boc BOC cell adhesion associated, oncogene regulated ISO RGD PMID:18772397 RGD:5490966 NCBI chr11:56,122,697...56,198,060
Ensembl chr11:56,122,750...56,198,059 		JBrowse link
G Dhh desert hedgehog signaling molecule IMP RGD PMID:11118005 RGD:634737 NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406 		JBrowse link
G Gli1 GLI family zinc finger 1 ISO RGD PMID:21186299 PMID:18772397 RGD:5491005, RGD:5490966 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251 		JBrowse link
G Gli3 GLI family zinc finger 3 ISS
ISO		 RGD PMID:15328011 PMID:18772397 RGD:1303367, RGD:5490966 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Lrp2 LDL receptor related protein 2 ISO RGD PMID:18772397 RGD:5490966 NCBI chr 3:54,189,305...54,346,769
Ensembl chr 3:54,189,308...54,346,708 		JBrowse link
G Ptch1 patched 1 ISS RGD PMID:9422511 RGD:704355 NCBI chr17:1,542,705...1,607,730
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Shh sonic hedgehog signaling molecule ISO RGD PMID:19506583 RGD:5490965 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Smo smoothened, frizzled class receptor ISO RGD PMID:9422511 RGD:704355 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    signaling pathway 2634
      signaling pathway pertinent to development 536
        Hedgehog signaling pathway 101
          altered Hedgehog signaling pathway 8
Path 2
Term Annotations click to browse term
  pathway 6091
    regulatory pathway 3867
      homeostasis pathway 1773
        cardiovascular system homeostasis pathway 423
          hematopoiesis pathway 101
            Hedgehog signaling pathway 101
              altered Hedgehog signaling pathway 8
paths to the root