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Gene: Sin3b (SIN3 transcription regulator family member B) Rattus norvegicus
Symbol: Sin3b
Name: SIN3 transcription regulator family member B
RGD ID: 1587989
Description: Predicted to contribute to histone deacetylase activity. Predicted to be involved in histone deacetylation; negative regulation of transcription by RNA polymerase II; and striated muscle tissue development. Predicted to localize to chromosome and cytoplasm. Orthologous to human SIN3B (SIN3 transcription regulator family member B); PARTICIPATES IN Hedgehog signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; buspirone.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: LOC683381; paired amphipathic helix protein Sin3b; similar to Paired amphipathic helix protein Sin3b (Transcriptional corepressor Sin3b) (Histone deacetylase complex subunit Sin3b); SIN3 homolog B, transcription regulator; SIN3 homolog B, transcription regulator (yeast); SIN3 transcription regulator homolog B; SIN3 transcription regulator homolog B (yeast); transcriptional regulator, SIN3B
Homo sapiens (human) : SIN3B (SIN3 transcription regulator family member B)  HGNC  Alliance
Mus musculus (house mouse) : Sin3b (transcriptional regulator, SIN3B (yeast))  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sin3b (SIN3 transcription regulator family member B)
Pan paniscus (bonobo/pygmy chimpanzee) : SIN3B (SIN3 transcription regulator family member B)
Canis lupus familiaris (dog) : SIN3B (SIN3 transcription regulator family member B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sin3b (SIN3 transcription regulator family member B)
Sus scrofa (pig) : SIN3B (SIN3 transcription regulator family member B)
Chlorocebus sabaeus (African green monkey) : SIN3B (SIN3 transcription regulator family member B)
Heterocephalus glaber (naked mole-rat) : Sin3b (SIN3 transcription regulator family member B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01618,842,456 - 18,860,086 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1618,842,456 - 18,860,086 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01618,711,540 - 18,728,708 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1617,365,514 - 17,383,086 (-)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Sin3b
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1587989
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.