ONTOLOGY REPORT - ANNOTATIONS
Term: regulation of synaptic transmission, glutamatergic
Accession: GO:0051966
browse the term
Definition: Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
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Cdk5
cyclin-dependent kinase 5
involved_in
IEA ISO
GO_REF:0000107 (PMID:24607229)
Ensembl RGD
PMID:24607229
GO_REF:0000107
NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
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Cln3
CLN3 lysosomal/endosomal transmembrane protein, battenin
involved_in
ISO
(PMID:29135436)
RGD
PMID:29135436
NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
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Cnr1
cannabinoid receptor 1
IMP
RGD
PMID:19725112
RGD:2314643
NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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Dgki
diacylglycerol kinase, iota
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:3584141 (PMID:21119615)
Ensembl RGD
PMID:21119615
GO_REF:0000107
NCBI chr 4:65,410,878...65,872,733
Ensembl chr 4:65,420,108...65,872,733
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Disc1
DISC1 scaffold protein
acts_upstream_of_or_within
IMP
PMID:24706880
MGI
PMID:24706880
RGD:11344933
NCBI chr19:53,014,201...53,223,617
Ensembl chr19:53,014,616...53,219,778
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Dkk1
dickkopf WNT signaling pathway inhibitor 1
involved_in
ISO
(PMID:25318560)
RGD
PMID:25318560
NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
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Frrs1l
ferric-chelate reductase 1-like
acts_upstream_of_or_within
ISO
(PMID:29276473)
RGD
PMID:29276473
NCBI chr 5:71,655,911...71,690,132
Ensembl chr 5:71,659,284...71,690,108
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Fxr1
FMR1 autosomal homolog 1
involved_in
ISS ISO IEA
GO_REF:0000024 (PMID:25456134) GO_REF:0000107
UniProt RGD Ensembl
PMID:25456134
GO_REF:0000024 GO_REF:0000107
NCBI chr 2:116,884,167...116,937,590
Ensembl chr 2:116,884,248...116,937,590
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Gria2
glutamate ionotropic receptor AMPA type subunit 2
involved_in
IMP
PMID:9697854
UniProt
PMID:9697854
RGD:8553822
NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
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Grm1
glutamate metabotropic receptor 1
involved_in
IDA IBA
PMID:11530226 GO_REF:0000033
GO_Central
PMID:11530226
GO_REF:0000033, RGD:8553469
NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170
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Grm2
glutamate metabotropic receptor 2
involved_in
NAS IBA
PMID:15993439 GO_REF:0000033
GO_Central
PMID:15993439
GO_REF:0000033, RGD:8553886
NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146
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Grm3
glutamate metabotropic receptor 3
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 4:24,364,854...24,643,972
Ensembl chr 4:24,365,115...24,609,804
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Grm4
glutamate metabotropic receptor 4
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821
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Grm5
glutamate metabotropic receptor 5
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274
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Grm6
glutamate metabotropic receptor 6
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr10:35,167,985...35,182,717
Ensembl chr10:35,167,985...35,182,717
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Grm7
glutamate metabotropic receptor 7
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 4:143,730,862...144,613,230
Ensembl chr 4:143,731,259...144,612,344
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Grm8
glutamate metabotropic receptor 8
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 4:55,805,762...56,731,690
Ensembl chr 4:55,805,955...56,730,831
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Homer1
homer scaffold protein 1
involved_in
ISS IMP
GO_REF:0000024 PMID:19345194
UniProt
PMID:19345194
GO_REF:0000024, RGD:8553291
NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785
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Lrrk2
leucine-rich repeat kinase 2
involved_in
ISS ISO
GO_REF:0000024 (PMID:24464040)
ParkinsonsUK-UCL RGD
PMID:24464040
GO_REF:0000024
NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703
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Mapk8ip2
mitogen-activated protein kinase 8 interacting protein 2
involved_in
ISO
(PMID:21048139)
RGD
PMID:21048139
NCBI chr 7:120,526,732...120,536,982
Ensembl chr 7:120,526,732...120,536,982
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Mef2c
myocyte enhancer factor 2C
involved_in
ISO
(PMID:18599438)
RGD
PMID:18599438
NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
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Mir142
microRNA 142
involved_in
ISO
(PMID:28100738)
RGD
PMID:28100738
NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967
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Nlgn3
neuroligin 3
involved_in
ISS ISO
GO_REF:0000024 (PMID:21808020)
BHF-UCL RGD
PMID:21808020
GO_REF:0000024
NCBI chr X:66,427,926...66,457,378
Ensembl chr X:66,429,458...66,451,876
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Ophn1
oligophrenin 1
involved_in acts_upstream_of_or_within
IBA ISO
GO_REF:0000033 (PMID:19481455)
GO_Central RGD
PMID:19481455
GO_REF:0000033
NCBI chr X:63,599,746...63,976,678
Ensembl chr X:63,603,042...63,976,633
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Plppr4
phospholipid phosphatase related 4
involved_in
ISS ISO IEA
GO_REF:0000024 (PMID:19766573) GO_REF:0000107
UniProt RGD Ensembl
PMID:19766573
GO_REF:0000024 GO_REF:0000107
NCBI chr 2:205,371,317...205,412,302
Ensembl chr 2:205,371,322...205,412,302
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Prkaca
protein kinase cAMP-activated catalytic subunit alpha
IDA
RGD
PMID:12562968
RGD:1580676
NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
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Psen1
presenilin 1
acts_upstream_of_or_within
ISO
MGI:1930937 (PMID:10097174)
RGD
PMID:10097174
NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
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Rnf167
ring finger protein 167
involved_in
ISS ISO
GO_REF:0000024 (PMID:23129617)
UniProt RGD
PMID:23129617
GO_REF:0000024
NCBI chr10:55,360,603...55,364,927
Ensembl chr10:55,360,543...55,364,927
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Serpine2
serpin family E member 2
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:2387774 (PMID:15509762)
Ensembl RGD
PMID:15509762
GO_REF:0000107
NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
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Syt1
synaptotagmin 1
involved_in
ISS ISO
GO_REF:0000024 (PMID:12526776)
ParkinsonsUK-UCL RGD
PMID:12526776
GO_REF:0000024
NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803
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Tprg1l
tumor protein p63 regulated 1-like
involved_in
IMP
PMID:26212709
UniProt
PMID:26212709
RGD:13792549
NCBI chr 5:164,722,151...164,725,358
Ensembl chr 5:164,710,285...164,725,425
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Ucn
urocortin
IDA
RGD
PMID:15102917
RGD:1642787
NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950
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Adora1
adenosine A1 receptor
IDA
K+-evoked glutamate release
RGD
PMID:16481441
RGD:1625231
NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
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Atad1
ATPase family, AAA domain containing 1
involved_in
ISS ISO
GO_REF:0000024 (PMID:21496646)
UniProt RGD
PMID:21496646
GO_REF:0000024
NCBI chr 1:230,544,227...230,610,524
Ensembl chr 1:230,544,047...230,596,548
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Drd2
dopamine receptor D2
involved_in acts_upstream_of_or_within
IBA ISO
GO_REF:0000033 MGI:1857875 (PMID:11160501)
GO_Central RGD
PMID:11160501
GO_REF:0000033
NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875
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Drd3
dopamine receptor D3
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
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Grik1
glutamate ionotropic receptor kainate type subunit 1
acts_upstream_of_or_within
IDA ISO
MGI:95815 (PMID:11985817)
RGD
PMID:11985817 PMID:17395219
RGD:1642466
NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645
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Grik2
glutamate ionotropic receptor kainate type subunit 2
involved_in acts_upstream_of_or_within
IDA ISO
PMID:16420445 MGI:95814 (PMID:11985817)
RGD
PMID:11985817 PMID:16420445
RGD:8554693
NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375
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Grik3
glutamate ionotropic receptor kainate type subunit 3
involved_in
IDA
PMID:16420445
UniProt
PMID:16420445
RGD:8554693
NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307
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Htr1b
5-hydroxytryptamine receptor 1B
IMP
RGD
PMID:17392733
RGD:1626454
NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549
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Htr2a
5-hydroxytryptamine receptor 2A
IMP
RGD
PMID:17016851
RGD:1624386
NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
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Myo5a
myosin VA
IMP
RGD
PMID:27771352
RGD:41412185
NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918
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Npy2r
neuropeptide Y receptor Y2
IMP
RGD
PMID:16190896
RGD:1642508
NCBI chr 2:167,901,999...167,912,165
Ensembl chr 2:167,903,879...167,905,024
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Pla2g6
phospholipase A2 group VI
IMP
RGD
PMID:15132431
RGD:6482754
NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114
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Prkn
parkin RBR E3 ubiquitin protein ligase
IMP
RGD
PMID:19033459
RGD:10413844
NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
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Dtnbp1
dystrobrevin binding protein 1
IMP
RGD
PMID:15345706
RGD:11251758
NCBI chr17:19,685,218...19,776,668
Ensembl chr17:19,685,215...19,776,661
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Rab3gap1
RAB3 GTPase activating protein catalytic subunit 1
involved_in
ISS ISO
GO_REF:0000024 (PMID:16782817)
ParkinsonsUK-UCL RGD
PMID:16782817
GO_REF:0000024
NCBI chr13:39,355,698...39,429,154
Ensembl chr13:39,352,247...39,429,169
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Kmo
kynurenine 3-monooxygenase
IMP
RGD
PMID:15829251
RGD:13513901
NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
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Stxbp1
syntaxin binding protein 1
IMP
RGD
PMID:16951547
RGD:12904030
NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369
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Adcyap1
adenylate cyclase activating polypeptide 1
IDA
RGD
PMID:16483357
RGD:2325299
NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
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Adora2a
adenosine A2a receptor
IDA
K+-evoked glutamate release
RGD
PMID:16481441
RGD:1625231
NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
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Cacng2
calcium voltage-gated channel auxiliary subunit gamma 2
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227
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Cacng3
calcium voltage-gated channel auxiliary subunit gamma 3
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:177,201,361...177,297,019
Ensembl chr 1:177,201,288...177,297,024
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Cacng4
calcium voltage-gated channel auxiliary subunit gamma 4
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr10:92,683,778...92,745,842
Ensembl chr10:92,683,761...92,746,126
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Cacng5
calcium voltage-gated channel auxiliary subunit gamma 5
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr10:92,827,441...92,869,632
Ensembl chr10:92,829,196...92,869,614
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Cacng7
calcium voltage-gated channel auxiliary subunit gamma 7
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:65,800,059...65,831,246
Ensembl chr 1:65,800,355...65,831,006
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Cacng8
calcium voltage-gated channel auxiliary subunit gamma 8
involved_in
IBA
GO_REF:0000033
GO_Central
GO_REF:0000033
NCBI chr 1:65,755,334...65,775,567
Ensembl chr 1:65,755,334...65,779,089
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Cckbr
cholecystokinin B receptor
IMP
RGD
PMID:18088282
RGD:2311325
NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881
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Ccl2
C-C motif chemokine ligand 2
involved_in
ISS ISO
GO_REF:0000024 (PMID:29993042)
UniProt RGD
PMID:29993042
GO_REF:0000024
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccr2
C-C motif chemokine receptor 2
involved_in
ISS ISO
GO_REF:0000024 (PMID:29993042)
UniProt RGD
PMID:29993042
GO_REF:0000024
NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
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Drd1
dopamine receptor D1
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:1857158 (PMID:8795639)
Ensembl RGD
PMID:8795639
GO_REF:0000107
NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
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Egfr
epidermal growth factor receptor
IMP
RGD
PMID:16648628
RGD:1581898
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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Glul
glutamate-ammonia ligase
IMP
RGD
PMID:10696145
RGD:2301558
NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
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Gria4
glutamate ionotropic receptor AMPA type subunit 4
involved_in
IMP
PMID:11036266
UniProt
PMID:11036266
RGD:8554601
NCBI chr 8:1,562,118...2,035,035
Ensembl chr 8:1,562,119...2,034,979
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Grin1
glutamate ionotropic receptor NMDA type subunit 1
involved_in
IDA ISS
PMID:19793963 GO_REF:0000114
ComplexPortal
PMID:19793963
GO_REF:0000114, RGD:150521643
NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
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Grin2a
glutamate ionotropic receptor NMDA type subunit 2A
involved_in
IDA ISS
PMID:19793963 GO_REF:0000114
ComplexPortal
PMID:19793963
GO_REF:0000114, RGD:150521643
NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637
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Grin2b
glutamate ionotropic receptor NMDA type subunit 2B
involved_in
IDA ISS
PMID:19793963 GO_REF:0000114
ComplexPortal
PMID:19793963
GO_REF:0000114, RGD:150521643
NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279
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Grin2c
glutamate ionotropic receptor NMDA type subunit 2C
involved_in
IDA
PMID:19793963
ComplexPortal
PMID:19793963
RGD:150521643
NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427
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Grin2d
glutamate ionotropic receptor NMDA type subunit 2D
involved_in
IDA
PMID:19793963
ComplexPortal
PMID:19793963
RGD:150521643
NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793
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Hdac6
histone deacetylase 6
IMP
RGD
PMID:22331421
RGD:9681553
NCBI chr X:14,550,645...14,572,445
Ensembl chr X:14,551,044...14,572,441
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Iqsec2
IQ motif and Sec7 domain ArfGEF 2
IMP
RGD
PMID:27009485
RGD:11049506
NCBI chr X:21,254,799...21,337,179
Ensembl chr X:21,254,914...21,336,584
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Ngfr
nerve growth factor receptor
IMP
medial septum and diagonal band of Broca (MS-DBB) neurons stimulated by NGF
RGD
PMID:18256260
RGD:5508750
NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
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Nlgn1
neuroligin 1
involved_in
IMP NAS IDA
PMID:19628693 PMID:16846852 PMID:19730411
CACAO ComplexPortal BHF-UCL
PMID:19628693 PMID:16846852 PMID:19730411
RGD:8554760 , RGD:151356651 , RGD:8554379
NCBI chr 2:108,256,236...109,181,530
Ensembl chr 2:108,257,824...109,002,464
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Nlgn2
neuroligin 2
involved_in
ISS ISO IEA
GO_REF:0000024 (PMID:15620359) GO_REF:0000107
BHF-UCL RGD Ensembl
PMID:15620359
GO_REF:0000024 GO_REF:0000107
NCBI chr10:54,544,461...54,557,854
Ensembl chr10:54,544,588...54,558,434
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Nlgn3
neuroligin 3
involved_in
ISS ISO
GO_REF:0000024 (PMID:21642956)
BHF-UCL RGD
PMID:21642956
GO_REF:0000024
NCBI chr X:66,427,926...66,457,378
Ensembl chr X:66,429,458...66,451,876
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Nps
neuropeptide S
involved_in acts_upstream_of_or_within
IBA ISO
GO_REF:0000033 (PMID:21437203)
GO_Central RGD
PMID:21437203
GO_REF:0000033
NCBI chr 1:190,077,040...190,080,821
Ensembl chr 1:190,077,040...190,080,821
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Nrxn1
neurexin 1
involved_in
ISS ISO IEA
GO_REF:0000024 (PMID:19098102) (PMID:19822762) GO_REF:0000107
BHF-UCL RGD Ensembl
PMID:19098102 PMID:19822762
GO_REF:0000024 GO_REF:0000107
NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710
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Ntrk1
neurotrophic receptor tyrosine kinase 1
IMP
RGD
PMID:21550171
RGD:5144124
NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
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Ntrk2
neurotrophic receptor tyrosine kinase 2
IMP
RGD
PMID:16983663
RGD:1626130
NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
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Oxtr
oxytocin receptor
IMP
RGD
PMID:18510735
RGD:2304108
NCBI chr 4:145,598,549...145,614,674
Ensembl chr 4:145,599,561...145,614,674
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Ptgs2
prostaglandin-endoperoxide synthase 2
IMP
RGD
PMID:18764909
RGD:2300272
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Ptk2b
protein tyrosine kinase 2 beta
involved_in
IMP
PMID:11239437
Alzheimers_University_of_Toronto
PMID:11239437
RGD:8553497
NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
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Reln
reelin
involved_in
IEA ISO
GO_REF:0000107 (PMID:17229826), (PMID:20357114), (PMID:21814183)
Ensembl RGD
PMID:17229826 PMID:20357114 PMID:21814183
GO_REF:0000107
NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211
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Ror2
receptor tyrosine kinase-like orphan receptor 2
IMP
RGD
PMID:25825749
RGD:11537351
NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152
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Shank2
SH3 and multiple ankyrin repeat domains 2
involved_in
ISO
(PMID:22699619)
RGD
PMID:22699619
NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394
G
Shank3
SH3 and multiple ankyrin repeat domains 3
involved_in
IEA ISO ISS
GO_REF:0000107 (PMID:21167025), (PMID:21423165), (PMID:21795692) GO_REF:0000024
Ensembl RGD BHF-UCL
PMID:21167025 PMID:21423165 PMID:21795692 PMID:21795692
GO_REF:0000024 GO_REF:0000107, RGD:7349315
NCBI chr 7:120,568,707...120,630,796
Ensembl chr 7:120,570,402...120,630,374
G
Tnr
tenascin R
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 MGI:2154583 (PMID:11161481)
Ensembl RGD
PMID:11161481
GO_REF:0000107
NCBI chr13:71,751,714...72,172,731
Ensembl chr13:72,091,585...72,167,641
G
Tshz3
teashirt zinc finger homeobox 3
involved_in
ISS ISO
GO_REF:0000024 (PMID:27668656)
UniProt RGD
PMID:27668656
GO_REF:0000024
NCBI chr 1:89,386,732...89,460,719
Ensembl chr 1:89,381,858...89,460,874
G
Slc38a2
solute carrier family 38, member 2
involved_in
IDA
PMID:18832333
UniProt
PMID:18832333
RGD:152995567
NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all