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ONTOLOGY REPORT - ANNOTATIONS


Term:synaptic transmission, glutamatergic
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Accession:GO:0035249 term browser browse the term
Definition:The vesicular release of glutamate from a presynapse, across a chemical synapse, the subsequent activation of glutamate receptors at the postsynapse of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.


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synaptic transmission, glutamatergic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor IDA RGD PMID:16644907 RGD:1625443 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Adrb2 adrenoceptor beta 2 IMP RGD PMID:17175110 RGD:5129150 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
JBrowse link
G Als2 alsin Rho guanine nucleotide exchange factor ALS2 acts_upstream_of_or_within ISO MGI:3522476 (MGI:3690398|PMID:17093100) RGD PMID:17093100 MGI:3690398 NCBI chr 9:60,613,182...60,686,394
Ensembl chr 9:60,613,167...60,670,737
JBrowse link
G Aph1b aph-1 homolog B, gamma secretase subunit acts_upstream_of_or_within ISO MGI:1915568 (MGI:3804503|PMID:18626010) RGD PMID:18626010 MGI:3804503 NCBI chr 8:67,429,198...67,454,735
Ensembl chr 8:67,429,198...67,450,243
JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A acts_upstream_of_or_within ISO MGI:1856209|MGI:2181384 (MGI:1340444|PMID:10322048), (MGI:3042538|PMID:14973254) RGD PMID:10322048 PMID:14973254 MGI:1340444 MGI:3042538 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225
JBrowse link
G Cacnb4 calcium voltage-gated channel auxiliary subunit beta 4 acts_upstream_of_or_within ISO MGI:1856936 (MGI:1340444|PMID:10322048) RGD PMID:10322048 MGI:1340444 NCBI chr 3:36,906,771...37,169,191
Ensembl chr 3:36,910,427...37,168,944
JBrowse link
G Cdh8 cadherin 8 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
MGI:3707077 (MGI:3703934|PMID:17392463)
GO_REF:0000107
RGD
Ensembl
PMID:17392463 PMID:21873635 GO_REF:0000107 MGI:3703934, RGD:13792537 NCBI chr19:5,494,038...5,901,810
Ensembl chr19:5,494,174...5,895,669
JBrowse link
G Cdk5 cyclin-dependent kinase 5 acts_upstream_of_or_within ISO (MGI:3033267|PMID:14769920) RGD PMID:14769920 MGI:3033267 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
JBrowse link
G Clcn3 chloride voltage-gated channel 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2183297 (MGI:2182197|PMID:11182090)
Ensembl
RGD
PMID:11182090 GO_REF:0000107 MGI:2182197 NCBI chr16:29,127,419...29,200,133
Ensembl chr16:29,127,419...29,200,119
JBrowse link
G Clstn3 calsyntenin 3 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5521290 (MGI:5516394|PMID:24094106)
Ensembl
RGD
PMID:24094106 GO_REF:0000107 MGI:5516394 NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769
JBrowse link
G Cnih2 cornichon family AMPA receptor auxiliary protein 2 acts_upstream_of_or_within IDA PMID:19265014 MGI PMID:19265014 RGD:8554136 NCBI chr 1:202,399,416...202,405,110
Ensembl chr 1:202,399,419...202,405,089
JBrowse link
G Cnih3 cornichon family AMPA receptor auxiliary protein 3 acts_upstream_of_or_within IDA PMID:19265014 MGI PMID:19265014 RGD:8554136 NCBI chr13:93,016,707...93,208,168
Ensembl chr13:93,099,784...93,208,121
JBrowse link
G Dcdc2 doublecortin domain containing 2 acts_upstream_of_or_within ISO MGI:5288003 (MGI:5908527|PMID:26250775), (MGI:5921447|PMID:24094509) RGD PMID:24094509 PMID:26250775 MGI:5908527 MGI:5921447 NCBI chr17:39,845,952...40,031,781
Ensembl chr17:39,845,952...40,030,743
JBrowse link
G Ext1 exostosin glycosyltransferase 1 acts_upstream_of_or_within ISO (MGI:5315031|PMID:22411800) RGD PMID:22411800 MGI:5315031 NCBI chr 7:84,375,769...84,654,625
Ensembl chr 7:84,375,784...84,655,357
JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 involved_in NAS PMID:15269270 UniProt PMID:15269270 RGD:8553901 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283
JBrowse link
G Grid1 glutamate ionotropic receptor delta type subunit 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr16:10,138,564...10,885,803
Ensembl chr16:10,138,925...10,885,808
JBrowse link
G Grid2 glutamate ionotropic receptor delta type subunit 2 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
PMID:21873635
MGI:2178052 (MGI:72217|PMID:7766857)
GO_REF:0000107
RGD
Ensembl
PMID:7766857 PMID:21873635 GO_REF:0000107 MGI:72217, RGD:13792537 NCBI chr 4:92,415,019...93,892,472
Ensembl chr 4:92,415,230...93,889,355
JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2176347|MGI:3623113|MGI:95815 (MGI:3531002|PMID:15509753), (MGI:3688795|PMID:15928066)
RGD PMID:15509753 PMID:15928066 PMID:21873635 MGI:3531002 MGI:3688795, RGD:13792537 NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1857979 (MGI:1202247|PMID:9580260), (MGI:3531002|PMID:15509753)
RGD PMID:9580260 PMID:15509753 PMID:21873635 MGI:1202247 MGI:3531002, RGD:13792537 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375
JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307
JBrowse link
G Grik4 glutamate ionotropic receptor kainate type subunit 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:42,903,043...43,331,990
Ensembl chr 8:42,905,056...43,193,751
JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2668206 (MGI:2449894|PMID:12533602)
RGD PMID:12533602 PMID:21873635 MGI:2449894, RGD:13792537 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 acts_upstream_of_or_within ISO MGI:1928270|MGI:1928279|MGI:1928281 (MGI:1888650|PMID:10963597), (MGI:65431|PMID:8313466) RGD PMID:8313466 PMID:10963597 MGI:1888650 MGI:65431 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D IMP RGD PMID:15107472 RGD:1642397 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793
JBrowse link
G Grm4 glutamate metabotropic receptor 4 involved_in TAS PMID:11906782 UniProt PMID:11906782 RGD:8554275 NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821
JBrowse link
G Grm8 glutamate metabotropic receptor 8 involved_in IDA PMID:15275822 UniProt PMID:15275822 RGD:6484726 NCBI chr 4:55,805,762...56,731,690
Ensembl chr 4:55,805,955...56,730,831
JBrowse link
G Napa NSF attachment protein alpha involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:104562 (MGI:4879076|PMID:21040848)
RGD PMID:21040848 PMID:21873635 MGI:4879076, RGD:13792537 NCBI chr 1:76,787,036...76,805,869
Ensembl chr 1:76,786,932...76,805,869
JBrowse link
G Napb NSF attachment protein beta involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000107
MGI:104563 (MGI:4879076|PMID:21040848)
PMID:21873635
Ensembl
RGD
PMID:21040848 PMID:21873635 GO_REF:0000107 MGI:4879076, RGD:13792537 NCBI chr 3:136,132,248...136,179,225
Ensembl chr 3:136,133,428...136,179,345
JBrowse link
G P2rx1 purinergic receptor P2X 1 IMP RGD PMID:16000618 RGD:1581702 NCBI chr10:57,618,586...57,633,648
Ensembl chr10:57,618,586...57,633,623
JBrowse link
G Plat plasminogen activator, tissue type IMP RGD PMID:15496678 RGD:1581924 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase acts_upstream_of_or_within ISO MGI:2678247 (MGI:2675710|PMID:12915482) RGD PMID:12915482 MGI:2675710 NCBI chr 1:48,688,651...49,882,520 JBrowse link
G Shc3 SHC adaptor protein 3 acts_upstream_of_or_within ISO MGI:1933356 (MGI:3577673|PMID:15716419) RGD PMID:15716419 MGI:3577673 NCBI chr17:13,652,247...13,772,710
Ensembl chr17:13,651,202...13,772,710
JBrowse link
G Slc17a6 solute carrier family 17 member 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542
JBrowse link
G Slc17a7 solute carrier family 17 member 7 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3617803 (MGI:3616153|PMID:15118123)
RGD PMID:15118123 PMID:21873635 MGI:3616153, RGD:13792537 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588
JBrowse link
G Slc17a8 solute carrier family 17 member 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:23,994,212...24,049,498
Ensembl chr 7:23,994,217...24,048,079
JBrowse link
G Unc13a unc-13 homolog A involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000002
MGI:1342278|MGI:2449468 (MGI:2158113|PMID:11832228), (MGI:2158119|PMID:11792326)
PMID:21873635
InterPro
RGD
PMID:11792326 PMID:11832228 PMID:21873635 GO_REF:0000002 MGI:2158113 MGI:2158119, RGD:13792537 NCBI chr16:18,336,229...18,381,811
Ensembl chr16:18,336,229...18,381,872
JBrowse link
G Unc13b unc-13 homolog B involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2449706|MGI:3051532 (MGI:2158113|PMID:11832228), (MGI:2158119|PMID:11792326)
RGD PMID:11792326 PMID:11832228 PMID:21873635 MGI:2158113 MGI:2158119, RGD:13792537 NCBI chr 5:57,288,999...57,504,110
Ensembl chr 5:57,289,227...57,502,926
JBrowse link
G Unc13c unc-13 homolog C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:74,247,026...74,697,629
Ensembl chr 8:74,247,899...74,673,223
JBrowse link
G Zzef1 zinc finger ZZ-type and EF-hand domain containing 1 acts_upstream_of_or_within ISO MGI:3796166 (MGI:6507270|PMID:25709106) RGD PMID:25709106 MGI:6507270 NCBI chr10:57,413,265...57,550,888
Ensembl chr10:57,411,149...57,549,568
JBrowse link
glutamate secretion, neurotransmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1339975 (MGI:5620820|PMID:25242307)
Ensembl
RGD
PMID:25242307 GO_REF:0000107 MGI:5620820 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 acts_upstream_of_or_within ISO MGI:97306 (MGI:5620820|PMID:25242307) RGD PMID:25242307 MGI:5620820 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383
JBrowse link
negative regulation of synaptic transmission, glutamatergic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor IDA K+-evoked glutamate release RGD PMID:16481441 RGD:1625231 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
JBrowse link
G Atad1 ATPase family, AAA domain containing 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5050342|PMID:21496646)
UniProt
RGD
PMID:21496646 GO_REF:0000024 MGI:5050342 NCBI chr 1:230,544,227...230,610,524
Ensembl chr 1:230,544,047...230,596,548
JBrowse link
G Drd2 dopamine receptor D2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2387895|MGI:2675755 (MGI:3628700|PMID:15489038)
MGI:1857875 (MGI:3610921|PMID:11160501)
RGD PMID:11160501 PMID:15489038 PMID:21873635 MGI:3610921 MGI:3628700, RGD:13792537 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link
G Drd3 dopamine receptor D3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 acts_upstream_of_or_within IDA
ISO
MGI:95815 (MGI:3575241|PMID:11985817) RGD PMID:11985817 PMID:17395219 MGI:3575241, RGD:1642466 NCBI chr11:27,169,739...27,571,131
Ensembl chr11:27,169,740...27,570,645
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 involved_in
acts_upstream_of_or_within
IDA
ISO
PMID:16420445
MGI:95814 (MGI:3575241|PMID:11985817)
RGD PMID:11985817 PMID:16420445 MGI:3575241, RGD:8554693 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375
JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 involved_in IDA PMID:16420445 UniProt PMID:16420445 RGD:8554693 NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B IMP RGD PMID:17392733 RGD:1626454 NCBI chr 8:82,513,572...82,534,892
Ensembl chr 8:82,517,360...82,534,549
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP RGD PMID:17016851 RGD:1624386 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928
JBrowse link
G Myo5a myosin VA IMP RGD PMID:27771352 RGD:41412185 NCBI chr 8:75,811,985...75,980,049
Ensembl chr 8:75,812,412...75,975,918
JBrowse link
G Npy2r neuropeptide Y receptor Y2 IMP RGD PMID:16190896 RGD:1642508 NCBI chr 2:167,901,999...167,912,165
Ensembl chr 2:167,903,879...167,905,024
JBrowse link
G Pla2g6 phospholipase A2 group VI IMP RGD PMID:15132431 RGD:6482754 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IMP RGD PMID:19033459 RGD:10413844 NCBI chr 1:48,688,651...49,882,520 JBrowse link
positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dtnbp1 dystrobrevin binding protein 1 IMP RGD PMID:15345706 RGD:11251758 NCBI chr17:19,685,218...19,776,668
Ensembl chr17:19,685,215...19,776,661
JBrowse link
G Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3652690|PMID:16782817)
ParkinsonsUK-UCL
RGD
PMID:16782817 GO_REF:0000024 MGI:3652690 NCBI chr13:39,355,698...39,429,154
Ensembl chr13:39,352,247...39,429,169
JBrowse link
positive regulation of glutamate secretion, neurotransmission term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kmo kynurenine 3-monooxygenase IMP RGD PMID:15829251 RGD:13513901 NCBI chr13:87,557,080...87,589,334
Ensembl chr13:87,557,286...87,588,881
JBrowse link
G Stxbp1 syntaxin binding protein 1 IMP RGD PMID:16951547 RGD:12904030 NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369
JBrowse link
positive regulation of synaptic transmission, glutamatergic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1 adenylate cyclase activating polypeptide 1 IDA RGD PMID:16483357 RGD:2325299 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773
JBrowse link
G Adora2a adenosine A2a receptor IDA K+-evoked glutamate release RGD PMID:16481441 RGD:1625231 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227
JBrowse link
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:177,201,990...177,296,473
Ensembl chr 1:177,201,288...177,297,024
JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:92,686,100...92,745,601
Ensembl chr10:92,683,761...92,746,126
JBrowse link
G Cacng5 calcium voltage-gated channel auxiliary subunit gamma 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:92,827,441...92,869,632
Ensembl chr10:92,829,196...92,869,614
JBrowse link
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:65,800,820...65,831,165
Ensembl chr 1:65,800,355...65,831,006
JBrowse link
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:65,755,334...65,775,567
Ensembl chr 1:65,755,334...65,779,089
JBrowse link
G Cckbr cholecystokinin B receptor IMP RGD PMID:18088282 RGD:2311325 NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:6275444|PMID:29993042)
UniProt
RGD
PMID:29993042 GO_REF:0000024 MGI:6275444 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:6275444|PMID:29993042)
UniProt
RGD
PMID:29993042 GO_REF:0000024 MGI:6275444 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Drd1 dopamine receptor D1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1857158 (MGI:82736|PMID:8795639)
Ensembl
RGD
PMID:8795639 GO_REF:0000107 MGI:82736 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
JBrowse link
G Egfr epidermal growth factor receptor IMP RGD PMID:16648628 RGD:1581898 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Glul glutamate-ammonia ligase IMP RGD PMID:10696145 RGD:2301558 NCBI chr13:65,969,064...66,035,121
Ensembl chr13:66,025,630...66,035,108
JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 involved_in IMP PMID:11036266 UniProt PMID:11036266 RGD:8554601 NCBI chr 8:1,562,118...2,035,035
Ensembl chr 8:1,562,119...2,034,979
JBrowse link
G Hdac6 histone deacetylase 6 IMP RGD PMID:22331421 RGD:9681553 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441
JBrowse link
G Iqsec2 IQ motif and Sec7 domain ArfGEF 2 IMP RGD PMID:27009485 RGD:11049506 NCBI chr  X:21,254,799...21,337,179
Ensembl chr  X:21,254,914...21,336,584
JBrowse link
G Ngfr nerve growth factor receptor IMP medial septum and diagonal band of Broca (MS-DBB) neurons stimulated by NGF RGD PMID:18256260 RGD:5508750 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
JBrowse link
G Nlgn1 neuroligin 1 involved_in IMP
IDA
PMID:19628693
PMID:19730411
BHF-UCL PMID:19628693 PMID:19730411 RGD:8554760, RGD:8554379 NCBI chr 2:108,256,236...109,181,530
Ensembl chr 2:108,257,824...109,002,464
JBrowse link
G Nlgn2 neuroligin 2 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:5284797|PMID:15620359)
GO_REF:0000107
BHF-UCL
RGD
Ensembl
PMID:15620359 GO_REF:0000024 GO_REF:0000107 MGI:5284797 NCBI chr10:54,544,588...54,557,854
Ensembl chr10:54,544,588...54,558,434
JBrowse link
G Nlgn3 neuroligin 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5320268|PMID:21642956)
BHF-UCL
RGD
PMID:21642956 GO_REF:0000024 MGI:5320268 NCBI chr  X:66,427,926...66,457,378
Ensembl chr  X:66,429,458...66,451,876
JBrowse link
G Nps neuropeptide S involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:4950795|PMID:21437203)
RGD PMID:21437203 PMID:21873635 MGI:4950795, RGD:13792537 NCBI chr 1:190,077,040...190,080,821
Ensembl chr 1:190,077,040...190,080,821
JBrowse link
G Nrxn1 neurexin 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:4366191|PMID:19822762), (MGI:5284755|PMID:19098102)
BHF-UCL
RGD
PMID:19098102 PMID:19822762 GO_REF:0000024 MGI:4366191 MGI:5284755 NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710
JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 IMP RGD PMID:21550171 RGD:5144124 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 IMP RGD PMID:16983663 RGD:1626130 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
JBrowse link
G Oxtr oxytocin receptor IMP RGD PMID:18510735 RGD:2304108 NCBI chr 4:145,598,549...145,614,674
Ensembl chr 4:145,599,561...145,614,674
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IMP RGD PMID:18764909 RGD:2300272 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta involved_in IMP PMID:11239437 Alzheimers_University_of_Toronto PMID:11239437 RGD:8553497 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
G Reln reelin involved_in IEA
ISO
GO_REF:0000107
(MGI:3765383|PMID:17229826), (MGI:4442532|PMID:20357114), (MGI:5619457|PMID:21814183)
Ensembl
RGD
PMID:17229826 PMID:20357114 PMID:21814183 GO_REF:0000107 MGI:3765383 MGI:4442532 MGI:5619457 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211
JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 IMP RGD PMID:25825749 RGD:11537351 NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152
JBrowse link
G Shank2 SH3 and multiple ankyrin repeat domains 2 involved_in ISO (MGI:5432971|PMID:22699619) RGD PMID:22699619 MGI:5432971 NCBI chr 1:199,146,210...199,590,962
Ensembl chr 1:199,169,429...199,589,394
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:4948759|PMID:21423165), (MGI:5285139|PMID:21167025), (MGI:5320264|PMID:21795692)
GO_REF:0000024
Ensembl
RGD
BHF-UCL
PMID:21167025 PMID:21423165 PMID:21795692 PMID:21795692 GO_REF:0000024 GO_REF:0000107 MGI:4948759 MGI:5285139 MGI:5320264, RGD:7349315 NCBI chr 7:120,568,707...120,630,796
Ensembl chr 7:120,570,402...120,630,374
JBrowse link
G Tnr tenascin R involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2154583 (MGI:3762112|PMID:11161481)
Ensembl
RGD
PMID:11161481 GO_REF:0000107 MGI:3762112 NCBI chr13:71,751,714...72,172,731
Ensembl chr13:72,091,585...72,167,641
JBrowse link
G Tshz3 teashirt zinc finger homeobox 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5819322|PMID:27668656)
UniProt
RGD
PMID:27668656 GO_REF:0000024 MGI:5819322 NCBI chr 1:89,386,732...89,460,719
Ensembl chr 1:89,381,858...89,460,874
JBrowse link
regulation of synaptic transmission, glutamatergic term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07002241.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AABR07061755.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G AC119691.1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Cdh2 cadherin 2 involved_in IMP
IBA
PMID:9655504
PMID:21873635
SynGO
GO_Central
PMID:9655504 PMID:21873635 RGD:12050123, RGD:13792537 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdk5 cyclin-dependent kinase 5 involved_in ISO (MGI:6094501|PMID:24607229) RGD PMID:24607229 MGI:6094501 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin involved_in ISO (MGI:6111006|PMID:29135436) RGD PMID:29135436 MGI:6111006 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
JBrowse link
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:19725112 RGD:2314643 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Dgki diacylglycerol kinase, iota involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3584141 (MGI:4936793|PMID:21119615)
RGD PMID:21119615 PMID:21873635 MGI:4936793, RGD:13792537 NCBI chr 4:65,410,878...65,872,733
Ensembl chr 4:65,420,108...65,872,733
JBrowse link
G Dgkz diacylglycerol kinase zeta involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:77,904,149...77,946,114
Ensembl chr 3:77,904,150...77,946,099
JBrowse link
G Disc1 DISC1 scaffold protein acts_upstream_of_or_within IMP PMID:24706880 MGI PMID:24706880 RGD:11344933 NCBI chr19:53,014,201...53,223,617
Ensembl chr19:53,014,616...53,219,778
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (MGI:5692401|PMID:25318560) RGD PMID:25318560 MGI:5692401 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 involved_in IMP PMID:9697854 UniProt PMID:9697854 RGD:8553822 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
JBrowse link
G Grm1 glutamate metabotropic receptor 1 involved_in IDA
IBA
PMID:11530226
PMID:21873635
UniProt
GO_Central
PMID:11530226 PMID:21873635 RGD:8553469, RGD:13792537 NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170
JBrowse link
G Grm2 glutamate metabotropic receptor 2 involved_in IBA
NAS
PMID:21873635
PMID:15993439
GO_Central
UniProt
PMID:21873635 PMID:15993439 RGD:13792537, RGD:8553886 NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146
JBrowse link
G Grm3 glutamate metabotropic receptor 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:24,364,854...24,643,972
Ensembl chr 4:24,365,115...24,609,804
JBrowse link
G Grm4 glutamate metabotropic receptor 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821
JBrowse link
G Grm5 glutamate metabotropic receptor 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274
JBrowse link
G Grm6 glutamate metabotropic receptor 6 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr10:35,167,985...35,182,717
Ensembl chr10:35,167,985...35,182,717
JBrowse link
G Grm7 glutamate metabotropic receptor 7 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:143,730,862...144,613,230
Ensembl chr 4:143,731,259...144,612,344
JBrowse link
G Grm8 glutamate metabotropic receptor 8 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:55,805,762...56,731,690
Ensembl chr 4:55,805,955...56,730,831
JBrowse link
G Homer1 homer scaffold protein 1 involved_in ISS
IMP
GO_REF:0000024
PMID:19345194
UniProt PMID:19345194 GO_REF:0000024, RGD:8553291 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785
JBrowse link
G Kalrn kalirin, RhoGEF kinase acts_upstream_of_or_within ISO MGI:3831292 (MGI:5289726|PMID:21880917) RGD PMID:21880917 MGI:5289726 NCBI chr11:66,198,155...66,803,166
Ensembl chr11:66,198,173...66,797,610
JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:5553024|PMID:24464040)
ParkinsonsUK-UCL
RGD
PMID:24464040 GO_REF:0000024 MGI:5553024 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703
JBrowse link
G Mapk8ip2 mitogen-activated protein kinase 8 interacting protein 2 involved_in ISO (MGI:4849330|PMID:21048139) RGD PMID:21048139 MGI:4849330 NCBI chr 7:120,526,732...120,536,982
Ensembl chr 7:120,526,732...120,536,982
JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in ISO (MGI:3804504|PMID:18599438) RGD PMID:18599438 MGI:3804504 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
JBrowse link
G Nlgn3 neuroligin 3 involved_in ISS
ISO
GO_REF:0000024
(MGI:5286761|PMID:21808020)
BHF-UCL
RGD
PMID:21808020 GO_REF:0000024 MGI:5286761 NCBI chr  X:66,427,926...66,457,378
Ensembl chr  X:66,429,458...66,451,876
JBrowse link
G Ophn1 oligophrenin 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:4359148|PMID:19481455)
RGD PMID:19481455 PMID:21873635 MGI:4359148, RGD:13792537 NCBI chr  X:63,599,746...63,976,678
Ensembl chr  X:63,603,042...63,976,633
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha IDA RGD PMID:12562968 RGD:1580676 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Psen1 presenilin 1 acts_upstream_of_or_within ISO MGI:1930937 (MGI:1334084|PMID:10097174) RGD PMID:10097174 MGI:1334084 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650
JBrowse link
G Serpine2 serpin family E member 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2387774 (MGI:3521551|PMID:15509762)
Ensembl
RGD
PMID:15509762 GO_REF:0000107 MGI:3521551 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826
JBrowse link
G Syt1 synaptotagmin 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3040539|PMID:12526776)
ParkinsonsUK-UCL
RGD
PMID:12526776 GO_REF:0000024 MGI:3040539 NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803
JBrowse link
G Tprg1l tumor protein p63 regulated 1-like involved_in IMP PMID:26212709 UniProt PMID:26212709 RGD:13792549 NCBI chr 5:164,722,151...164,725,358
Ensembl chr 5:164,710,285...164,725,425
JBrowse link
G Ucn urocortin IDA RGD PMID:15102917 RGD:1642787 NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950
JBrowse link
G Vom2r-ps45 vomeronasal 2 receptor, pseudogene 45 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:66,463,177...66,490,650 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    signaling 7460
      cell-cell signaling 1735
        synaptic signaling 919
          trans-synaptic signaling 892
            anterograde trans-synaptic signaling 883
              chemical synaptic transmission 883
                synaptic transmission, glutamatergic 117
                  glutamate secretion, neurotransmission + 6
                  negative regulation of synaptic transmission, glutamatergic + 13
                  positive regulation of synaptic transmission, glutamatergic + 38
                  regulation of synaptic transmission, glutamatergic + 84
Path 2
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      cell communication 7543
        cell-cell signaling 1735
          synaptic signaling 919
            trans-synaptic signaling 892
              anterograde trans-synaptic signaling 883
                chemical synaptic transmission 883
                  synaptic transmission, glutamatergic 117
                    glutamate secretion, neurotransmission + 6
                    negative regulation of synaptic transmission, glutamatergic + 13
                    positive regulation of synaptic transmission, glutamatergic + 38
                    regulation of synaptic transmission, glutamatergic + 84
paths to the root