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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of synaptic transmission, glutamatergic
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Accession:GO:0051967 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
Synonyms:exact_synonym: down regulation of synaptic transmission, glutamatergic;   downregulation of synaptic transmission, glutamatergic
 narrow_synonym: inhibition of synaptic transmission, glutamatergic


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negative regulation of synaptic transmission, glutamatergic term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor IDA K+-evoked glutamate release RGD PMID:16481441 RGD:1625231 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Atad1 ATPase family, AAA domain containing 1 ISO
ISS
(MGI:MGI:5050342|PMID:21496646)
GO_REF:0000024
RGD
UniProt
PMID:21496646 GO_REF:0000024, MGI:MGI:5050342 NCBI chr 1:251,234,702...251,386,996
Ensembl chr 1:251,235,508...251,387,002
JBrowse link
G Drd2 dopamine receptor D2 ISO
IBA
MGI:MGI:1857875|MGI:MGI:2387895|MGI:MGI:2675755 (MGI:MGI:3610921|PMID:11160501), (MGI:MGI:3628700|PMID:15489038)
PMID:21873635
RGD PMID:11160501, PMID:15489038, PMID:21873635 MGI:MGI:3610921, MGI:MGI:3628700, RGD:13792537 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd3 dopamine receptor D3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr11:61,819,102...61,883,223
Ensembl chr11:61,822,077...61,874,327
JBrowse link
G Grik1 glutamate ionotropic receptor kainate type subunit 1 IDA
ISO
MGI:MGI:95815 (MGI:MGI:3575241|PMID:11985817) RGD PMID:11985817, PMID:17395219 MGI:MGI:3575241, RGD:1642466 NCBI chr11:27,811,954...28,213,940
Ensembl chr11:27,811,957...27,971,359
JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 IDA
ISO
PMID:16420445
MGI:MGI:95814 (MGI:MGI:3575241|PMID:11985817)
RGD PMID:11985817, PMID:16420445 MGI:MGI:3575241, RGD:8554693 NCBI chr20:53,791,428...54,517,691
Ensembl chr20:53,789,760...54,517,709
JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 IDA PMID:16420445 UniProt PMID:16420445 RGD:8554693 NCBI chr 5:143,500,441...143,715,546
Ensembl chr 5:143,500,441...143,715,546
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B IMP RGD PMID:17392733 RGD:1626454 NCBI chr 8:89,113,984...89,130,830
Ensembl chr 8:89,129,453...89,130,991
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP RGD PMID:17016851 RGD:1624386 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Npy2r neuropeptide Y receptor Y2 IMP RGD PMID:16190896 RGD:1642508 NCBI chr 2:181,528,949...181,538,145
Ensembl chr 2:181,530,832...181,531,978
JBrowse link
G Pla2g6 phospholipase A2 group VI IMP RGD PMID:15132431 RGD:6482754 NCBI chr 7:120,519,479...120,559,716
Ensembl chr 7:120,519,467...120,559,347
JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase IMP RGD PMID:19033459 RGD:10413844 NCBI chr 1:48,880,015...50,069,998 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    signaling 7583
      negative regulation of signaling 1373
        negative regulation of synaptic transmission 83
          negative regulation of synaptic transmission, glutamatergic 12
            negative regulation of glutamate secretion, neurotransmission 0
Path 2
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      cell communication 7664
        cell-cell signaling 1738
          synaptic signaling 917
            trans-synaptic signaling 889
              anterograde trans-synaptic signaling 880
                chemical synaptic transmission 880
                  modulation of chemical synaptic transmission 656
                    negative regulation of synaptic transmission 83
                      negative regulation of synaptic transmission, glutamatergic 12
                        negative regulation of glutamate secretion, neurotransmission 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.