Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:SCH 23390
go back to main search page
Accession:CHEBI:73297 term browser browse the term
Definition:A benzazepine that is 2,3,4,5-tetrahydro-3-benzazepine bearing a phenyl substituent at position 1, a methyl substituent at position 3, a chloro substituent at position 7 and a hydroxy substituent at position 8.
Synonyms:exact_synonym: 8-chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-ol
 related_synonym: 7-chloro-3-methyl-1-phenyl-1,2,4,5-tetrahydro-3-benzazepin-8-ol;   Formula=C17H18ClNO;   InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3;   InChIKey=GOTMKOSCLKVOGG-UHFFFAOYSA-N;   SMILES=CN1CCc2cc(Cl)c(O)cc2C(C1)c1ccccc1
 xref_mesh: MESH:C534628
 xref: PMID:21242715;   PMID:21864553;   PMID:23123352;   PMID:23320810;   PMID:23597562;   Reaxys:4323128;   Wikipedia:SCH_23390


show annotations for term's descendants           Sort by:
SCH 23390 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC6 ATP binding cassette subfamily C member 6 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCC6 mRNA CTD PMID:19564919 NCBI chr16:16,149,565...16,223,494
Ensembl chr16:16,149,565...16,223,522 		JBrowse link
G ABCD4 ATP binding cassette subfamily D member 4 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCD4 mRNA CTD PMID:19564919 NCBI chr14:74,285,269...74,302,934
Ensembl chr14:74,285,269...74,303,055 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCG2 mRNA CTD PMID:19564919 NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628 		JBrowse link
G ABRA actin binding Rho activating protein multiple interactions ISO [Methamphetamine co-treated with SCH 23390] affects the expression of ABRA mRNA CTD PMID:19564919 NCBI chr 8:106,759,483...106,770,244
Ensembl chr 8:106,759,483...106,770,244 		JBrowse link
G ACOT1 acyl-CoA thioesterase 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of ACOT1 mRNA CTD PMID:19564919 NCBI chr14:73,490,933...73,543,796
Ensembl chr14:73,537,143...73,543,796 		JBrowse link
G ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif 9 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of ADAMTS9 mRNA
SCH 23390 results in decreased expression of ADAMTS9 mRNA		 CTD PMID:19564919 NCBI chr 3:64,515,654...64,688,000
Ensembl chr 3:64,515,654...64,688,000 		JBrowse link
G ADCY5 adenylate cyclase 5 multiple interactions ISO SCH 23390 inhibits the reaction [ADCY5 protein affects the susceptibility to Clozapine]; SCH 23390 inhibits the reaction [ADCY5 protein affects the susceptibility to Haloperidol] CTD PMID:12223546 NCBI chr 3:123,282,296...123,449,090
Ensembl chr 3:123,282,296...123,449,090 		JBrowse link
G AHSA2P activator of HSP90 ATPase homolog 2, pseudogene multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of AHSA2 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of AHSA2 mRNA] CTD PMID:19564919 NCBI chr 2:61,177,418...61,188,925
Ensembl chr 2:61,177,418...61,191,203
Ensembl chr 2:61,177,418...61,191,203 		JBrowse link
G AIF1 allograft inflammatory factor 1 multiple interactions ISO SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in increased expression of AIF1 protein] CTD PMID:30922767 NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021 		JBrowse link
G ALG1 ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of ALG1 mRNA CTD PMID:19564919 NCBI chr16:5,071,843...5,087,379
Ensembl chr16:5,033,702...5,087,379 		JBrowse link
G ANKRD44 ankyrin repeat domain 44 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of ANKRD44 mRNA
SCH 23390 results in decreased expression of ANKRD44 mRNA		 CTD PMID:19564919 NCBI chr 2:196,967,014...197,310,780
Ensembl chr 2:196,967,017...197,311,173 		JBrowse link
G APLNR apelin receptor multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of APLNR mRNA CTD PMID:19564919 NCBI chr11:57,233,591...57,237,250
Ensembl chr11:57,233,577...57,237,250 		JBrowse link
G APOLD1 apolipoprotein L domain containing 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of APOLD1 mRNA CTD PMID:19564919 NCBI chr12:12,725,917...12,791,466
Ensembl chr12:12,725,917...12,829,975 		JBrowse link
G ARC activity regulated cytoskeleton associated protein multiple interactions
decreases expression		 ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ARC mRNA]
SCH 23390 results in decreased expression of ARC mRNA		 CTD PMID:11085305 PMID:19564919 NCBI chr 8:142,611,049...142,614,479
Ensembl chr 8:142,611,049...142,614,479 		JBrowse link
G ARL5B ADP ribosylation factor like GTPase 5B multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of ARL5B mRNA
SCH 23390 results in increased expression of ARL5B mRNA		 CTD PMID:19564919 NCBI chr10:18,659,431...18,681,639
Ensembl chr10:18,659,431...18,681,639 		JBrowse link
G ATF3 activating transcription factor 3 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of ATF3 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF3 mRNA]
SCH 23390 results in decreased expression of ATF3 mRNA		 CTD PMID:19564919 NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777 		JBrowse link
G ATF4 activating transcription factor 4 multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF4 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF4 protein] CTD PMID:19564919 NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683 		JBrowse link
G AVP arginine vasopressin affects expression
multiple interactions		 ISO SCH 23390 affects the expression of AVP mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of AVP mRNA		 CTD PMID:19564919 NCBI chr20:3,082,556...3,084,724
Ensembl chr20:3,082,556...3,084,724 		JBrowse link
G B3GALT4 beta-1,3-galactosyltransferase 4 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of B3GALT4 mRNA
SCH 23390 results in decreased expression of B3GALT4 mRNA		 CTD PMID:19564919 NCBI chr 6:33,277,123...33,278,825
Ensembl chr 6:33,277,123...33,284,832 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in increased expression of BAX protein] CTD PMID:30922767 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions ISO SCH 23390 inhibits the reaction [Cocaine results in increased phosphorylation of BCL2 protein]
SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in decreased expression of BCL2 protein]		 CTD PMID:19879923 PMID:30922767 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L15 BCL2 like 15 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of BCL2L15 mRNA CTD PMID:19564919 NCBI chr 1:113,876,816...113,887,581
Ensembl chr 1:113,876,816...113,887,581 		JBrowse link
G BCL6 BCL6 transcription repressor multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of BCL6 mRNA CTD PMID:19564919 NCBI chr 3:187,721,377...187,745,468
Ensembl chr 3:187,721,377...187,745,725 		JBrowse link
G BHMT2 betaine--homocysteine S-methyltransferase 2 affects expression
multiple interactions		 ISO SCH 23390 affects the expression of BHMT2 mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of BHMT2 mRNA		 CTD PMID:19564919 NCBI chr 5:79,069,767...79,090,069
Ensembl chr 5:79,069,767...79,090,069 		JBrowse link
G C16orf89 chromosome 16 open reading frame 89 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of C10H16ORF89 mRNA
SCH 23390 results in decreased expression of C10H16ORF89 mRNA		 CTD PMID:19564919 NCBI chr16:5,042,772...5,065,956
Ensembl chr16:5,044,122...5,066,110 		JBrowse link
G C1orf210 chromosome 1 open reading frame 210 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of C5H1ORF210 mRNA CTD PMID:19564919 NCBI chr 1:43,281,877...43,285,857
Ensembl chr 1:43,281,877...43,285,617 		JBrowse link
G C1QTNF7 C1q and TNF related 7 decreases expression
multiple interactions		 ISO SCH 23390 results in decreased expression of C1QTNF7 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of C1QTNF7 mRNA		 CTD PMID:19564919 NCBI chr 4:15,339,786...15,446,167
Ensembl chr 4:15,339,818...15,446,167 		JBrowse link
G C8orf58 chromosome 8 open reading frame 58 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of C15H8ORF58 mRNA
SCH 23390 results in decreased expression of C15H8ORF58 mRNA		 CTD PMID:19564919 NCBI chr 8:22,599,599...22,604,142
Ensembl chr 8:22,599,599...22,604,150 		JBrowse link
G CA4 carbonic anhydrase 4 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CAR4 mRNA CTD PMID:19564919 NCBI chr17:60,149,973...60,179,021
Ensembl chr17:60,149,942...60,170,899 		JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 protein] CTD PMID:20340177 NCBI chr 7:81,946,444...82,443,956
Ensembl chr 7:81,946,444...82,443,956 		JBrowse link
G CALCA calcitonin related polypeptide alpha multiple interactions ISO SCH 23390 inhibits the reaction [Dextroamphetamine results in increased expression of CALCA protein] CTD PMID:11398184 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354 		JBrowse link
G CAMK2A calcium/calmodulin dependent protein kinase II alpha multiple interactions ISO SCH 23390 inhibits the reaction [SK&F 83959 promotes the reaction [CAMK2A protein binds to DRD3 protein]] CTD PMID:19217379 NCBI chr 5:150,219,491...150,290,130
Ensembl chr 5:150,219,491...150,290,093 		JBrowse link
G CASP3 caspase 3 multiple interactions ISO SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in increased cleavage of CASP3 protein] CTD PMID:30922767 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CC2D1B coiled-coil and C2 domain containing 1B multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CC2D1B mRNA CTD PMID:19564919 NCBI chr 1:52,350,597...52,366,205
Ensembl chr 1:52,345,723...52,366,205 		JBrowse link
G CCDC117 coiled-coil domain containing 117 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CCDC117 mRNA CTD PMID:19564919 NCBI chr22:28,772,695...28,789,301
Ensembl chr22:28,772,674...28,789,301 		JBrowse link
G CCN1 cellular communication network factor 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CCN1 mRNA CTD PMID:19564919 NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CCR5 mRNA CTD PMID:19564919 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206 		JBrowse link
G CD86 CD86 molecule multiple interactions ISO SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in increased expression of CD86 mRNA] CTD PMID:30922767 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression
multiple interactions		 ISO SCH 23390 results in increased expression of CDKN1A mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of CDKN1A mRNA		 CTD PMID:19564919 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CEBPB CCAAT enhancer binding protein beta multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CEBPB mRNA CTD PMID:19564919 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668 		JBrowse link
G CEP104 centrosomal protein 104 multiple interactions
affects expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CEP104 mRNA
SCH 23390 affects the expression of CEP104 mRNA		 CTD PMID:19564919 NCBI chr 1:3,812,086...3,857,211
Ensembl chr 1:3,812,086...3,857,396 		JBrowse link
G CHORDC1 cysteine and histidine rich domain containing 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CHORDC1 mRNA CTD PMID:19564919 NCBI chr11:90,200,429...90,223,049
Ensembl chr11:90,200,429...90,223,077 		JBrowse link
G CHRNB1 cholinergic receptor nicotinic beta 1 subunit decreases expression ISO SCH 23390 results in decreased expression of CHRNB1 mRNA CTD PMID:19564919 NCBI chr17:7,445,061...7,457,710
Ensembl chr17:7,445,061...7,457,710 		JBrowse link
G CHRNE cholinergic receptor nicotinic epsilon subunit multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CHRNE mRNA
SCH 23390 results in increased expression of CHRNE mRNA		 CTD PMID:19564919 NCBI chr17:4,897,771...4,908,677
Ensembl chr17:4,897,771...4,934,438 		JBrowse link
G CHTF18 chromosome transmission fidelity factor 18 decreases expression
multiple interactions		 ISO SCH 23390 results in decreased expression of CHTF18 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CHTF18 mRNA		 CTD PMID:19564919 NCBI chr16:788,620...798,074
Ensembl chr16:788,046...800,737 		JBrowse link
G CITED4 Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CITED4 mRNA CTD PMID:19564919 NCBI chr 1:40,861,054...40,862,363
Ensembl chr 1:40,861,054...40,862,363 		JBrowse link
G CLVS2 clavesin 2 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CLVS2 mRNA
SCH 23390 results in decreased expression of CLVS2 mRNA		 CTD PMID:19564919 NCBI chr 6:122,996,235...123,072,925
Ensembl chr 6:122,996,235...123,072,925 		JBrowse link
G CNOT6L CCR4-NOT transcription complex subunit 6 like multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CNOT6L mRNA
SCH 23390 results in increased expression of CNOT6L mRNA		 CTD PMID:19564919 NCBI chr 4:77,713,387...77,820,269
Ensembl chr 4:77,713,387...77,819,615 		JBrowse link
G COL3A1 collagen type III alpha 1 chain decreases expression ISO SCH 23390 results in decreased expression of COL3A1 mRNA CTD PMID:19564919 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746 		JBrowse link
G COQ10B coenzyme Q10B multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of COQ10B mRNA CTD PMID:19564919 NCBI chr 2:197,453,552...197,475,310
Ensembl chr 2:197,453,493...197,475,310 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions ISO SCH 23390 inhibits the reaction [[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine binds to and results in increased activity of DRD1 protein] which results in increased phosphorylation of CREB1 protein]; SCH 23390 inhibits the reaction [[Dopamine binds to and results in increased activity of DRD1 protein] which results in increased phosphorylation of CREB1 protein]; SCH 23390 inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased phosphorylation of CREB1 protein] CTD PMID:14622123 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G CREM cAMP responsive element modulator multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CREM mRNA CTD PMID:19564919 NCBI chr10:35,126,846...35,212,958
Ensembl chr10:35,126,791...35,212,958 		JBrowse link
G CRH corticotropin releasing hormone multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CRH mRNA; SCH 23390 affects the reaction [Cocaine affects the expression of CRH mRNA]
SCH 23390 results in increased expression of CRH mRNA		 CTD PMID:11597771 PMID:19564919 NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464 		JBrowse link
G CRISPLD1 cysteine rich secretory protein LCCL domain containing 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CRISPLD1 mRNA CTD PMID:19564919 NCBI chr 8:74,984,505...75,034,558
Ensembl chr 8:74,984,505...75,034,558 		JBrowse link
G CRYAB crystallin alpha B multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of CRYAB mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CRYAB mRNA]
SCH 23390 results in increased expression of CRYAB mRNA		 CTD PMID:19564919 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722 		JBrowse link
G CSRP2 cysteine and glycine rich protein 2 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CSRP2 mRNA CTD PMID:19564919 NCBI chr12:76,858,709...76,879,019
Ensembl chr12:76,858,709...76,879,023 		JBrowse link
G CWC25 CWC25 spliceosome associated protein homolog decreases expression ISO SCH 23390 results in decreased expression of CWC25 mRNA CTD PMID:19564919 NCBI chr17:38,800,441...38,825,321
Ensembl chr17:38,800,441...38,825,355 		JBrowse link
G CYYR1 cysteine and tyrosine rich 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of CYYR1 mRNA CTD PMID:19564919 NCBI chr21:26,466,216...26,573,286
Ensembl chr21:26,466,209...26,573,286 		JBrowse link
G DAD1 defender against cell death 1 multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DAD1 mRNA] CTD PMID:19564919 NCBI chr14:22,564,907...22,589,224
Ensembl chr14:22,564,907...22,589,224 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of DDIT3 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DDIT3 mRNA] CTD PMID:19564919 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G DDIT4 DNA damage inducible transcript 4 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of DDIT4 mRNA CTD PMID:19564919 NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036 		JBrowse link
G DMKN dermokine decreases expression ISO SCH 23390 results in decreased expression of DMKN mRNA CTD PMID:19564919 NCBI chr19:35,497,220...35,513,649
Ensembl chr19:35,497,220...35,513,658 		JBrowse link
G DNAH1 dynein axonemal heavy chain 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of DNAH1 mRNA CTD PMID:19564919 NCBI chr 3:52,310,920...52,400,492
Ensembl chr 3:52,316,319...52,400,492 		JBrowse link
G DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJA1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJA1 mRNA] CTD PMID:19564919 NCBI chr 9:33,025,273...33,039,907
Ensembl chr 9:33,025,273...33,039,907 		JBrowse link
G DNAJB1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJB1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJB1 mRNA] CTD PMID:19564919 NCBI chr19:14,514,769...14,560,391
Ensembl chr19:14,514,769...14,560,391 		JBrowse link
G DNAJB4 DnaJ heat shock protein family (Hsp40) member B4 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJB4 mRNA CTD PMID:19564919 NCBI chr 1:77,979,175...78,017,964
Ensembl chr 1:77,979,175...78,017,964 		JBrowse link
G DNAJB5 DnaJ heat shock protein family (Hsp40) member B5 multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJB5 mRNA] CTD PMID:19564919 NCBI chr 9:34,989,745...34,998,900
Ensembl chr 9:34,989,641...34,998,900 		JBrowse link
G DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJC3 mRNA] CTD PMID:19564919 NCBI chr13:95,677,139...95,794,988
Ensembl chr13:95,677,139...95,794,988 		JBrowse link
G DNASE1 deoxyribonuclease 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of DNASE1 mRNA CTD PMID:19564919 NCBI chr16:3,611,760...3,665,461
Ensembl chr16:3,611,728...3,680,143 		JBrowse link
G DOK3 docking protein 3 multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of DOK3 mRNA
SCH 23390 results in increased expression of DOK3 mRNA		 CTD PMID:19564919 NCBI chr 5:177,501,904...177,511,100
Ensembl chr 5:177,501,904...177,511,274 		JBrowse link
G DRD1 dopamine receptor D1 affects binding
decreases activity
multiple interactions		 EXP
ISO		 SCH 23390 binds to DRD1 protein
SCH 23390 binds to Drd1 protein
SCH 23390 results in decreased activity of DRD1 protein
8-fluoro-12-(4-methylpiperazin-1-yl)-6H-(1)benzothieno(2,3-b)(1,5)benzodiazepine inhibits the reaction [SCH 23390 binds to DRD1 protein]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine binds to and results in increased activity of DRD1 protein] which results in increased susceptibility to ethyl acetate]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Cocaine results in increased expression of FOS protein]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP1 mRNA]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP6 mRNA]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to A 86929; [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to Amphetamine; [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to Methamphetamine; [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to Methylphenidate; [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to Nicotine; Aluminum inhibits the reaction [SCH 23390 binds to DRD1 protein]; boldine analog inhibits the reaction [SCH 23390 binds to DRD1 protein]; Cadmium inhibits the reaction [SCH 23390 binds to DRD1 protein]; Cocaine affects the reaction [SCH 23390 binds to DRD1 protein]; Copper inhibits the reaction [SCH 23390 binds to DRD1 protein]; Dopamine deficiency inhibits the reaction [SCH 23390 binds to DRD1 protein]; Gadolinium inhibits the reaction [SCH 23390 binds to DRD1 protein]; Glyphosate inhibits the reaction [SCH 23390 binds to DRD1 protein]; Lanthanum inhibits the reaction [SCH 23390 binds to DRD1 protein]; Methamphetamine inhibits the reaction [SCH 23390 binds to DRD1 protein]; Pilocarpine inhibits the reaction [SCH 23390 binds to DRD1 protein]; SCH 23390 binds to and results in decreased activity of DRD1 protein; SCH 23390 inhibits the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine binds to and results in increased activity of DRD1 protein]; SCH 23390 inhibits the reaction [[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine binds to and results in increased activity of DRD1 protein] which results in increased phosphorylation of CREB1 protein]; SCH 23390 inhibits the reaction [[Dopamine binds to and results in increased activity of DRD1 protein] which results in increased phosphorylation of CREB1 protein]; SCH 23390 inhibits the reaction [[SK&F 82958 binds to and results in increased activity of DRD1 protein] which results in increased phosphorylation of CREB1 protein]; SCH 23390 inhibits the reaction [A 86929 binds to and results in increased activity of DRD1 protein]; SCH 23390 inhibits the reaction [A 86929 promotes the reaction [DRD1 protein results in increased chemical synthesis of Cyclic AMP]]; SCH 23390 inhibits the reaction [Simvastatin promotes the reaction [[SK&F 82958 analog results in increased activity of DRD1 protein] which results in increased abundance of Cyclic AMP]]; SCH 23390 inhibits the reaction [Simvastatin promotes the reaction [SK&F 82958 analog results in increased activity of DRD1 protein]]; SCH 23390 inhibits the reaction [SK&F 82958 analog results in increased activity of DRD1 protein]; Zinc Acetate inhibits the reaction [SCH 23390 binds to DRD1 protein]; zinc chloride inhibits the reaction [SCH 23390 binds to DRD1 protein]; Zinc Sulfate inhibits the reaction [SCH 23390 binds to DRD1 protein]
[SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to A 86929; [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to adrogolide hydrochloride; [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to Methamphetamine; Amlodipine inhibits the reaction [SCH 23390 binds to DRD1 protein]; Diltiazem inhibits the reaction [SCH 23390 binds to DRD1 protein]; Flunarizine inhibits the reaction [SCH 23390 binds to DRD1 protein]; manidipine inhibits the reaction [SCH 23390 binds to DRD1 protein]; NR3C1 protein promotes the reaction [SCH 23390 binds to DRD1 protein]; SCH 23390 binds to and results in decreased activity of DRD1 protein; SCH 23390 inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole]; Verapamil inhibits the reaction [SCH 23390 binds to DRD1 protein]
SCH 23390 inhibits the reaction [A 68930 affects the localization of DRD1 protein]; SCH 23390 inhibits the reaction [A 77636 affects the localization of DRD1 protein]; SCH 23390 inhibits the reaction [A 77636 results in increased activity of DRD1 protein]; SCH 23390 inhibits the reaction [A 86929 affects the localization of DRD1 protein]; SCH 23390 inhibits the reaction [A 86929 results in increased activity of DRD1 protein]; SCH 23390 inhibits the reaction [Apomorphine results in increased activity of DRD1 protein]; SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; SCH 23390 inhibits the reaction [dihydrexidine results in increased activity of DRD1 protein]; SCH 23390 inhibits the reaction [dinapsoline affects the localization of DRD1 protein]; SCH 23390 inhibits the reaction [dinapsoline results in increased activity of DRD1 protein]; SCH 23390 inhibits the reaction [Dopamine affects the localization of DRD1 protein]; SCH 23390 inhibits the reaction [Dopamine results in increased activity of DRD1 protein]; SCH 23390 inhibits the reaction [Isoquinolines affects the localization of DRD1 protein]; SCH 23390 inhibits the reaction [Isoquinolines results in increased activity of DRD1 protein]; SCH 23390 inhibits the reaction [SK&F 81297 affects the localization of DRD1 protein]; SCH 23390 inhibits the reaction [SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; SCH 23390 inhibits the reaction [SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; SCH 23390 inhibits the reaction [SK&F 82958 affects the localization of DRD1 protein]		 CTD
RGD		 PMID:1418306 PMID:1724532 PMID:1833784 PMID:2213551 PMID:2891082 More... RGD:1600981 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182 		JBrowse link
G DRD2 dopamine receptor D2 multiple interactions ISO SCH 23390 inhibits the reaction [[[Apomorphine binds to and results in increased activity of DRD1 protein] co-treated with [Apomorphine binds to and results in increased activity of DRD2 protein]] results in decreased susceptibility to Pentylenetetrazole] CTD PMID:8103921 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691 		JBrowse link
G DRD3 dopamine receptor D3 multiple interactions ISO SCH 23390 inhibits the reaction [SK&F 83959 promotes the reaction [CAMK2A protein binds to DRD3 protein]] CTD PMID:19217379 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407 		JBrowse link
G DUSP1 dual specificity phosphatase 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of DUSP1 mRNA; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP1 mRNA] CTD PMID:11701771 PMID:19564919 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195 		JBrowse link
G DUSP14 dual specificity phosphatase 14 multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of DUSP14 mRNA
SCH 23390 results in increased expression of DUSP14 mRNA		 CTD PMID:19564919 NCBI chr17:37,488,566...37,513,498
Ensembl chr17:37,489,891...37,513,501 		JBrowse link
G DUSP6 dual specificity phosphatase 6 multiple interactions ISO [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP6 mRNA] CTD PMID:11701771 NCBI chr12:89,347,235...89,352,501
Ensembl chr12:89,347,235...89,352,501 		JBrowse link
G EFNB1 ephrin B1 increases expression ISO SCH 23390 results in increased expression of EFNB1 mRNA CTD PMID:19564919 NCBI chr  X:68,829,021...68,842,160
Ensembl chr  X:68,829,021...68,842,160 		JBrowse link
G EGFL7 EGF like domain multiple 7 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of EGFL7 mRNA CTD PMID:19564919 NCBI chr 9:136,658,856...136,672,678
Ensembl chr 9:136,658,856...136,672,678 		JBrowse link
G EGFLAM EGF like, fibronectin type III and laminin G domains multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of EGFLAM mRNA CTD PMID:19564919 NCBI chr 5:38,258,559...38,465,480
Ensembl chr 5:38,258,409...38,465,480 		JBrowse link
G EGR1 early growth response 1 multiple interactions ISO SCH 23390 inhibits the reaction [[Reserpine co-treated with Levodopa] results in increased expression of EGR1 mRNA]; SCH 23390 inhibits the reaction [Dextroamphetamine results in increased expression of EGR1 mRNA]; SCH 23390 inhibits the reaction [Methylphenidate results in increased expression of EGR1 mRNA]; SCH 23390 inhibits the reaction [Reserpine promotes the reaction [Dextroamphetamine results in increased expression of EGR1 mRNA]] CTD PMID:1347779 PMID:9890435 PMID:16549270 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G EGR2 early growth response 2 decreases expression ISO SCH 23390 results in decreased expression of EGR2 mRNA CTD PMID:19564919 NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,819,167 		JBrowse link
G EGR4 early growth response 4 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of EGR4 mRNA
SCH 23390 results in decreased expression of EGR4 mRNA		 CTD PMID:19564919 NCBI chr 2:73,290,929...73,293,548
Ensembl chr 2:73,290,929...73,293,701 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions ISO SCH 23390 inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein] CTD PMID:17303341 NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518 		JBrowse link
G ELK1 ETS transcription factor ELK1 multiple interactions ISO SCH 23390 inhibits the reaction [Dronabinol results in increased phosphorylation of and results in increased activity of ELK1 protein] CTD PMID:11553284 NCBI chr  X:47,635,520...47,650,604
Ensembl chr  X:47,635,521...47,650,604 		JBrowse link
G EPCAM epithelial cell adhesion molecule multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of EPCAM mRNA CTD PMID:19564919 NCBI chr 2:47,369,311...47,387,020
Ensembl chr 2:47,345,158...47,387,601 		JBrowse link
G ERN1 endoplasmic reticulum to nucleus signaling 1 multiple interactions ISO SCH 23390 inhibits the reaction [Cocaine results in increased expression of ERN1 protein] CTD PMID:17303341 NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819 		JBrowse link
G ERRFI1 ERBB receptor feedback inhibitor 1 increases expression
multiple interactions		 ISO SCH 23390 results in increased expression of ERRFI1 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of ERRFI1 mRNA		 CTD PMID:19564919 NCBI chr 1:8,011,727...8,026,309
Ensembl chr 1:8,004,404...8,026,309 		JBrowse link
G FAAH fatty acid amide hydrolase multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of FAAH mRNA CTD PMID:19564919 NCBI chr 1:46,394,317...46,413,845
Ensembl chr 1:46,394,317...46,413,848 		JBrowse link
G FADD Fas associated via death domain increases expression ISO SCH 23390 results in increased expression of FADD protein CTD PMID:18580876 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390 		JBrowse link
G FCGR2B Fc gamma receptor IIb multiple interactions ISO SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in increased expression of FCGR2B mRNA] CTD PMID:30922767 NCBI chr 1:161,647,243...161,678,654
Ensembl chr 1:161,663,143...161,678,654 		JBrowse link
G FGF4 fibroblast growth factor 4 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of FGF4 mRNA CTD PMID:19564919 NCBI chr11:69,771,022...69,775,341
Ensembl chr11:69,771,022...69,775,341 		JBrowse link
G FMO2 flavin containing dimethylaniline monoxygenase 2 multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of FMO2 mRNA
SCH 23390 results in increased expression of FMO2 mRNA		 CTD PMID:19564919 NCBI chr 1:171,185,208...171,212,686
Ensembl chr 1:171,185,249...171,212,686 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of FOS mRNA; [Pilocarpine co-treated with SCH 23390] results in increased expression of FOS protein; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Cocaine results in increased expression of FOS protein]; SCH 23390 inhibits the reaction [A 68930 results in increased expression of FOS mRNA]; SCH 23390 inhibits the reaction [Amphetamine results in increased expression of FOS protein]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOS protein]; SCH 23390 inhibits the reaction [Dextroamphetamine results in increased expression of FOS mRNA]; SCH 23390 inhibits the reaction [dihydrexidine results in increased expression of FOS mRNA]
SCH 23390 results in decreased expression of FOS mRNA		 CTD PMID:2118661 PMID:8511714 PMID:8864302 PMID:9751140 PMID:11172061 More... NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230 		JBrowse link
G FOSB FosB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOSB protein alternative form]; SCH 23390 inhibits the reaction [Cocaine results in increased expression of FOSB protein]
SCH 23390 inhibits the reaction [Amphetamine results in increased expression of FOSB mRNA]		 CTD PMID:16674926 PMID:18822274 PMID:19710318 NCBI chr19:45,467,996...45,475,179
Ensembl chr19:45,467,995...45,475,179 		JBrowse link
G FTCD formimidoyltransferase cyclodeaminase multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of FTCD mRNA
SCH 23390 results in increased expression of FTCD mRNA		 CTD PMID:19564919 NCBI chr21:46,136,262...46,155,579
Ensembl chr21:46,136,160...46,155,579 		JBrowse link
G GABRR3 gamma-aminobutyric acid type A receptor subunit rho3 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of GABRR3 mRNA CTD PMID:19564919 NCBI chr 3:97,985,102...98,035,315
Ensembl chr 3:97,985,102...98,035,315 		JBrowse link
G GADD45B growth arrest and DNA damage inducible beta multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of GADD45B mRNA CTD PMID:19564919 NCBI chr19:2,476,127...2,478,257
Ensembl chr19:2,476,122...2,478,259 		JBrowse link
G GADD45G growth arrest and DNA damage inducible gamma multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of GADD45G mRNA CTD PMID:19564919 NCBI chr 9:89,605,012...89,606,555
Ensembl chr 9:89,605,012...89,606,555 		JBrowse link
G GAS8 growth arrest specific 8 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of GAS8 mRNA
SCH 23390 results in decreased expression of GAS8 mRNA		 CTD PMID:19564919 NCBI chr16:90,019,633...90,044,960
Ensembl chr16:90,019,629...90,044,975 		JBrowse link
G GDF15 growth differentiation factor 15 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of GDF15 mRNA CTD PMID:19564919 NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176 		JBrowse link
G GEM GTP binding protein overexpressed in skeletal muscle multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] affects the expression of GEM mRNA
SCH 23390 results in decreased expression of GEM mRNA		 CTD PMID:19564919 NCBI chr 8:94,249,253...94,262,319
Ensembl chr 8:94,249,253...94,262,350 		JBrowse link
G GFAP glial fibrillary acidic protein multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of GFAP protein] CTD PMID:16088948 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937 		JBrowse link
G GFRA4 GDNF family receptor alpha 4 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of GFRA4 mRNA CTD PMID:19564919 NCBI chr20:3,659,248...3,663,399
Ensembl chr20:3,659,248...3,663,399 		JBrowse link
G GJA4 gap junction protein alpha 4 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of GJA4 mRNA CTD PMID:19564919 NCBI chr 1:34,792,999...34,795,747
Ensembl chr 1:34,792,999...34,795,747 		JBrowse link
G GPR150 G protein-coupled receptor 150 decreases expression
multiple interactions		 ISO SCH 23390 results in decreased expression of GPR150 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of GPR150 mRNA		 CTD PMID:19564919 NCBI chr 5:95,620,087...95,622,142
Ensembl chr 5:95,620,087...95,622,142 		JBrowse link
G GPR4 G protein-coupled receptor 4 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of GPR4 mRNA CTD PMID:19564919 NCBI chr19:45,589,764...45,602,212
Ensembl chr19:45,589,764...45,602,212 		JBrowse link
G GPR65 G protein-coupled receptor 65 increases expression
multiple interactions		 ISO SCH 23390 results in increased expression of GPR65 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of GPR65 mRNA		 CTD PMID:19564919 NCBI chr14:88,005,135...88,014,811
Ensembl chr14:88,005,135...88,014,811 		JBrowse link
G H4C9 H4 clustered histone 9 multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of HIST1H4B mRNA
SCH 23390 results in increased expression of HIST1H4B mRNA		 CTD PMID:19564919 NCBI chr 6:27,139,282...27,139,678
Ensembl chr 6:27,139,282...27,139,678 		JBrowse link
G HCRT hypocretin neuropeptide precursor multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of HCRT mRNA
SCH 23390 results in decreased expression of HCRT mRNA		 CTD PMID:19564919 NCBI chr17:42,184,060...42,185,452
Ensembl chr17:42,184,060...42,185,452 		JBrowse link
G HERPUD1 homocysteine inducible ER protein with ubiquitin like domain 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of HERPUD1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HERPUD1 mRNA] CTD PMID:19564919 NCBI chr16:56,932,142...56,944,864
Ensembl chr16:56,932,142...56,944,864 		JBrowse link
G HES5 hes family bHLH transcription factor 5 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of HES5 mRNA CTD PMID:19564919 NCBI chr 1:2,528,745...2,530,263
Ensembl chr 1:2,528,745...2,530,263 		JBrowse link
G HMGA1 high mobility group AT-hook 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of HMGA1 mRNA CTD PMID:19564919 NCBI chr 6:34,236,873...34,246,231
Ensembl chr 6:34,236,873...34,246,231 		JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of HMOX1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HMOX1 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HMOX1 protein] CTD PMID:19564919 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HOMER1 homer scaffold protein 1 multiple interactions ISO SCH 23390 inhibits the reaction [Methylphenidate results in increased expression of HOMER1 mRNA] CTD PMID:16549270 NCBI chr 5:79,372,636...79,514,134
Ensembl chr 5:79,372,636...79,514,134 		JBrowse link
G HRC histidine rich calcium binding protein decreases expression
multiple interactions		 ISO SCH 23390 results in decreased expression of HRC mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of HRC mRNA		 CTD PMID:19564919 NCBI chr19:49,151,198...49,155,396
Ensembl chr19:49,151,198...49,155,396 		JBrowse link
G HSF2BP heat shock transcription factor 2 binding protein multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of HSF2BP mRNA
SCH 23390 results in decreased expression of HSF2BP mRNA		 CTD PMID:19564919 NCBI chr21:43,444,972...43,659,488
Ensembl chr21:43,529,186...43,659,488 		JBrowse link
G HSPA12B heat shock protein family A (Hsp70) member 12B multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine results in decreased expression of HSPA12B mRNA] CTD PMID:19564919 NCBI chr20:3,732,685...3,753,111
Ensembl chr20:3,732,685...3,753,111 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of HSPA5 mRNA; SCH 23390 inhibits the reaction [Cocaine results in increased expression of HSPA5 protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HSPA5 mRNA] CTD PMID:17303341 PMID:19564919 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of HSPB1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HSPB1 mRNA] CTD PMID:19564919 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295 		JBrowse link
G HSPB8 heat shock protein family B (small) member 8 multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HSPB8 mRNA] CTD PMID:19564919 NCBI chr12:119,178,931...119,194,746
Ensembl chr12:119,171,555...119,224,855 		JBrowse link
G HYCC2 hyccin PI4KA lipid kinase complex subunit 2 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of HYCC2 mRNA CTD PMID:19564919 NCBI chr 2:200,973,718...201,071,671
Ensembl chr 2:200,973,718...201,071,671 		JBrowse link
G ICAM2 intercellular adhesion molecule 2 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of ICAM2 mRNA CTD PMID:19564919 NCBI chr17:64,002,595...64,020,633
Ensembl chr17:64,002,594...64,020,634 		JBrowse link
G IDNK IDNK gluconokinase multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of IDNK mRNA CTD PMID:19564919 NCBI chr 9:83,623,006...83,644,123
Ensembl chr 9:83,623,049...83,644,130 		JBrowse link
G IL10 interleukin 10 multiple interactions EXP SCH 23390 inhibits the reaction [Reserpine results in decreased expression of IL10 mRNA]; SCH 23390 inhibits the reaction [Reserpine results in decreased expression of IL10 protein] CTD PMID:16985181 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL1A interleukin 1 alpha multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of IL1A mRNA
SCH 23390 results in increased expression of IL1A mRNA		 CTD PMID:19564919 NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493 		JBrowse link
G IMPG1 interphotoreceptor matrix proteoglycan 1 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] affects the expression of IMPG1 mRNA
SCH 23390 results in decreased expression of IMPG1 mRNA		 CTD PMID:19564919 NCBI chr 6:75,921,114...76,072,662
Ensembl chr 6:75,921,114...76,072,678 		JBrowse link
G IQCF1 IQ motif containing F1 multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of IQCF1 mRNA
SCH 23390 results in increased expression of IQCF1 mRNA		 CTD PMID:19564919 NCBI chr 3:51,894,876...51,903,353
Ensembl chr 3:51,894,876...51,903,353 		JBrowse link
G JAML junction adhesion molecule like increases expression
multiple interactions		 ISO SCH 23390 results in increased expression of JAML mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of JAML mRNA		 CTD PMID:19564919 NCBI chr11:118,193,725...118,225,011
Ensembl chr11:118,193,725...118,225,092 		JBrowse link
G JUNB JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of JUNB mRNA; SCH 23390 inhibits the reaction [Dextroamphetamine results in increased expression of JUNB mRNA]; SCH 23390 inhibits the reaction [Reserpine promotes the reaction [Dextroamphetamine results in increased expression of JUNB mRNA]] CTD PMID:1347779 PMID:19564919 NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315 		JBrowse link
G KIF15 kinesin family member 15 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of KIF15 mRNA
SCH 23390 results in decreased expression of KIF15 mRNA		 CTD PMID:19564919 NCBI chr 3:44,761,794...44,868,687
Ensembl chr 3:44,761,721...44,873,376 		JBrowse link
G KLF5 KLF transcription factor 5 decreases expression ISO SCH 23390 results in decreased expression of KLF5 mRNA CTD PMID:19564919 NCBI chr13:73,054,976...73,077,538
Ensembl chr13:73,054,976...73,077,541 		JBrowse link
G KLHL15 kelch like family member 15 multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of KLHL15 mRNA
SCH 23390 results in increased expression of KLHL15 mRNA		 CTD PMID:19564919 NCBI chr  X:23,983,720...24,027,186
Ensembl chr  X:23,983,716...24,027,186 		JBrowse link
G KRT7 keratin 7 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of KRT7 mRNA
SCH 23390 results in decreased expression of KRT7 mRNA		 CTD PMID:19564919 NCBI chr12:52,233,243...52,255,853
Ensembl chr12:52,232,520...52,252,186 		JBrowse link
G L3MBTL1 L3MBTL histone methyl-lysine binding protein 1 increases expression
multiple interactions		 ISO SCH 23390 results in increased expression of L3MBTL1 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of L3MBTL1 mRNA		 CTD PMID:19564919 NCBI chr20:43,507,697...43,550,954
Ensembl chr20:43,489,442...43,550,954 		JBrowse link
G LGALS9 galectin 9 decreases expression
multiple interactions		 ISO SCH 23390 results in decreased expression of LGALS9 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of LGALS9 mRNA		 CTD PMID:19564919 NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560 		JBrowse link
G LRRC28 leucine rich repeat containing 28 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of LRRC28 mRNA CTD PMID:19564919 NCBI chr15:99,251,481...99,390,729
Ensembl chr15:99,251,362...99,390,729 		JBrowse link
G LTBP1 latent transforming growth factor beta binding protein 1 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of LTBP1 mRNA
SCH 23390 results in decreased expression of LTBP1 mRNA		 CTD PMID:19564919 NCBI chr 2:32,946,953...33,399,509
Ensembl chr 2:32,946,953...33,399,509 		JBrowse link
G LTC4S leukotriene C4 synthase multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of LTC4S mRNA CTD PMID:19564919 NCBI chr 5:179,793,986...179,796,647
Ensembl chr 5:179,793,980...179,796,647 		JBrowse link
G LTK leukocyte receptor tyrosine kinase multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of LTK mRNA CTD PMID:19564919 NCBI chr15:41,503,637...41,513,827
Ensembl chr15:41,503,637...41,513,887 		JBrowse link
G LURAP1 leucine rich adaptor protein 1 decreases expression
multiple interactions		 ISO SCH 23390 results in decreased expression of LURAP1 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of LURAP1 mRNA		 CTD PMID:19564919 NCBI chr 1:46,203,334...46,221,256
Ensembl chr 1:46,203,334...46,221,256 		JBrowse link
G LYRM9 LYR motif containing 9 decreases expression
multiple interactions		 ISO SCH 23390 results in decreased expression of LYRM9 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of LYRM9 mRNA		 CTD PMID:19564919 NCBI chr17:27,878,358...27,893,365
Ensembl chr17:27,878,314...27,894,752 		JBrowse link
G MAFF MAF bZIP transcription factor F multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of MAFF mRNA CTD PMID:19564919 NCBI chr22:38,201,994...38,216,511
Ensembl chr22:38,200,767...38,216,507 		JBrowse link
G MANF mesencephalic astrocyte derived neurotrophic factor multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of MANF mRNA] CTD PMID:19564919 NCBI chr 3:51,385,291...51,389,397
Ensembl chr 3:51,385,291...51,389,397 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP
ISO		 SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; SCH 23390 inhibits the reaction [SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]
SCH 23390 inhibits the reaction [[Oxidopamine co-treated with Levodopa] results in increased expression of MAPK1 protein]; SCH 23390 inhibits the reaction [Dronabinol results in increased activity of MAPK1 protein]		 CTD PMID:11553284 PMID:19187092 PMID:20956312 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions EXP
ISO		 SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; SCH 23390 inhibits the reaction [SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]
SCH 23390 inhibits the reaction [[Oxidopamine co-treated with Levodopa] results in increased expression of MAPK3 protein]; SCH 23390 inhibits the reaction [Dronabinol results in increased activity of MAPK3 protein]		 CTD PMID:11553284 PMID:19187092 PMID:20956312 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MASTL microtubule associated serine/threonine kinase like multiple interactions
affects expression		 ISO [Methamphetamine co-treated with SCH 23390] affects the expression of MASTL mRNA
SCH 23390 affects the expression of MASTL mRNA		 CTD PMID:19564919 NCBI chr10:27,154,479...27,187,953
Ensembl chr10:27,154,824...27,187,953 		JBrowse link
G MC4R melanocortin 4 receptor multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of MC4R mRNA CTD PMID:19564919 NCBI chr18:60,371,062...60,372,775
Ensembl chr18:60,371,062...60,372,775 		JBrowse link
G MCM8 minichromosome maintenance 8 homologous recombination repair factor multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of MCM8 mRNA
SCH 23390 results in decreased expression of MCM8 mRNA		 CTD PMID:19564919 NCBI chr20:5,950,652...5,998,977
Ensembl chr20:5,950,652...5,998,977 		JBrowse link
G MFSD10 major facilitator superfamily domain containing 10 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of MFSD10 mRNA CTD PMID:19564919 NCBI chr 4:2,930,567...2,934,825
Ensembl chr 4:2,930,561...2,934,834 		JBrowse link
G MN1 MN1 proto-oncogene, transcriptional regulator multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of MN1 mRNA CTD PMID:19564919 NCBI chr22:27,748,277...27,801,756
Ensembl chr22:27,748,277...27,801,756 		JBrowse link
G MPG N-methylpurine DNA glycosylase multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of MPG mRNA CTD PMID:19564919 NCBI chr16:77,007...85,846
Ensembl chr16:77,007...85,851 		JBrowse link
G MUS81 MUS81 structure-specific endonuclease subunit multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of MUS81 mRNA CTD PMID:19564919 NCBI chr11:65,859,674...65,867,653
Ensembl chr11:65,857,126...65,867,653 		JBrowse link
G MYLK myosin light chain kinase multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] affects the expression of MYLK mRNA
SCH 23390 results in decreased expression of MYLK mRNA		 CTD PMID:19564919 NCBI chr 3:123,610,049...123,884,332
Ensembl chr 3:123,610,049...123,884,332 		JBrowse link
G NAB2 NGFI-A binding protein 2 multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of NAB2 mRNA
SCH 23390 results in increased expression of NAB2 mRNA		 CTD PMID:19564919 NCBI chr12:57,089,114...57,095,476
Ensembl chr12:57,089,043...57,095,476 		JBrowse link
G NDST3 N-deacetylase and N-sulfotransferase 3 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of NDST3 mRNA
SCH 23390 results in decreased expression of NDST3 mRNA		 CTD PMID:19564919 NCBI chr 4:118,033,322...118,258,634
Ensembl chr 4:118,033,618...118,258,634 		JBrowse link
G NEURL2 neuralized E3 ubiquitin protein ligase 2 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of NEURL2 mRNA
SCH 23390 results in decreased expression of NEURL2 mRNA		 CTD PMID:19564919 NCBI chr20:45,888,634...45,891,208
Ensembl chr20:45,888,625...45,891,208 		JBrowse link
G NFATC3 nuclear factor of activated T cells 3 affects expression
multiple interactions		 ISO SCH 23390 affects the expression of NFATC3 mRNA
SCH 23390 inhibits the reaction [Methamphetamine affects the localization of NFATC3 protein]		 CTD PMID:15644446 PMID:19564919 NCBI chr16:68,085,370...68,229,259
Ensembl chr16:68,084,751...68,229,259 		JBrowse link
G NFATC4 nuclear factor of activated T cells 4 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of NFATC4 mRNA; SCH 23390 inhibits the reaction [Methamphetamine affects the localization of NFATC4 protein] CTD PMID:15644446 PMID:19564919 NCBI chr14:24,366,911...24,379,604
Ensembl chr14:24,365,673...24,379,604 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine affects the localization of NFE2L2 protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of NFE2L2 mRNA] CTD PMID:19564919 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFIL3 nuclear factor, interleukin 3 regulated multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of NFIL3 mRNA CTD PMID:19564919 NCBI chr 9:91,409,045...91,483,497
Ensembl chr 9:91,409,045...91,423,832 		JBrowse link
G NFKBIA NFKB inhibitor alpha multiple interactions ISO SCH 23390 inhibits the reaction [Cocaine results in increased activity of NFKBIA protein] CTD PMID:19183502 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NKX2-6 NK2 homeobox 6 affects expression
multiple interactions		 ISO SCH 23390 affects the expression of NKX2-6 mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of NKX2-6 mRNA		 CTD PMID:19564919 NCBI chr 8:23,701,740...23,706,756
Ensembl chr 8:23,701,740...23,706,756 		JBrowse link
G NKX6-2 NK6 homeobox 2 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of NKX6-2 mRNA CTD PMID:19564919 NCBI chr10:132,783,181...132,786,147
Ensembl chr10:132,783,179...132,786,147 		JBrowse link
G NOTUM notum, palmitoleoyl-protein carboxylesterase multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of NOTUM mRNA CTD PMID:19564919 NCBI chr17:81,952,507...81,961,187
Ensembl chr17:81,952,507...81,961,840 		JBrowse link
G NPAS4 neuronal PAS domain protein 4 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of NPAS4 mRNA CTD PMID:19564919 NCBI chr11:66,409,158...66,426,707
Ensembl chr11:66,421,035...66,426,707 		JBrowse link
G NPTX2 neuronal pentraxin 2 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of NPTX2 mRNA CTD PMID:19564919 NCBI chr 7:98,617,285...98,629,869
Ensembl chr 7:98,617,285...98,629,869 		JBrowse link
G NPY neuropeptide Y increases expression
multiple interactions		 ISO SCH 23390 results in increased expression of NPY protein
[Prazosin co-treated with SCH 23390] inhibits the reaction [Phenylpropanolamine results in decreased expression of NPY protein]		 CTD PMID:7644023 PMID:21989786 NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 multiple interactions ISO NR3C1 protein promotes the reaction [SCH 23390 binds to DRD1 protein] CTD PMID:11226678 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512 		JBrowse link
G NR4A2 nuclear receptor subfamily 4 group A member 2 multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of NR4A2 mRNA
SCH 23390 results in increased expression of NR4A2 mRNA		 CTD PMID:19564919 NCBI chr 2:156,324,437...156,332,721
Ensembl chr 2:156,324,437...156,342,348 		JBrowse link
G NR4A3 nuclear receptor subfamily 4 group A member 3 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of NR4A3 mRNA CTD PMID:19564919 NCBI chr 9:99,821,885...99,866,891
Ensembl chr 9:99,821,855...99,866,891 		JBrowse link
G NRM nurim multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of NRM mRNA CTD PMID:19564919 NCBI chr 6:30,688,049...30,691,420
Ensembl chr 6:30,688,047...30,691,420 		JBrowse link
G NUP210L nucleoporin 210 like multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of NUP210L mRNA
SCH 23390 results in increased expression of NUP210L mRNA		 CTD PMID:19564919 NCBI chr 1:153,992,690...154,155,116
Ensembl chr 1:153,992,690...154,155,116 		JBrowse link
G OBSL1 obscurin like cytoskeletal adaptor 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of OBSL1 mRNA CTD PMID:19564919 NCBI chr 2:219,547,206...219,571,539
Ensembl chr 2:219,550,728...219,571,859 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of OGG1 mRNA CTD PMID:19564919 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219 		JBrowse link
G OXGR1 oxoglutarate receptor 1 increases expression
multiple interactions		 ISO SCH 23390 results in increased expression of OXGR1 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of OXGR1 mRNA		 CTD PMID:19564919 NCBI chr13:96,985,713...96,994,730
Ensembl chr13:96,985,713...96,994,730 		JBrowse link
G OXT oxytocin/neurophysin I prepropeptide multiple interactions
affects expression		 ISO [Methamphetamine co-treated with SCH 23390] affects the expression of OXT mRNA
SCH 23390 affects the expression of OXT mRNA		 CTD PMID:19564919 NCBI chr20:3,071,620...3,072,517
Ensembl chr20:3,071,620...3,072,517 		JBrowse link
G P4HA1 prolyl 4-hydroxylase subunit alpha 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of P4HA1 mRNA CTD PMID:19564919 NCBI chr10:73,007,217...73,096,866
Ensembl chr10:73,007,217...73,096,974 		JBrowse link
G P4HA2 prolyl 4-hydroxylase subunit alpha 2 multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of P4HA2 mRNA
SCH 23390 results in increased expression of P4HA2 mRNA		 CTD PMID:19564919 NCBI chr 5:132,190,147...132,227,853
Ensembl chr 5:132,190,147...132,295,315 		JBrowse link
G PADI6 peptidyl arginine deiminase 6 decreases expression
multiple interactions		 ISO SCH 23390 results in decreased expression of PADI6 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of PADI6 mRNA		 CTD PMID:19564919 NCBI chr 1:17,372,196...17,401,699
Ensembl chr 1:17,372,196...17,401,699 		JBrowse link
G PARD6G par-6 family cell polarity regulator gamma multiple interactions
affects expression		 ISO [Methamphetamine co-treated with SCH 23390] affects the expression of PARD6G mRNA
SCH 23390 affects the expression of PARD6G mRNA		 CTD PMID:19564919 NCBI chr18:80,157,232...80,247,514
Ensembl chr18:80,157,232...80,247,514 		JBrowse link
G PCLAF PCNA clamp associated factor multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of PCLAF mRNA CTD PMID:19564919 NCBI chr15:64,364,304...64,387,687
Ensembl chr15:64,364,304...64,387,687 		JBrowse link
G PCSK1 proprotein convertase subtilisin/kexin type 1 multiple interactions
affects expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of PCSK1 mRNA
SCH 23390 affects the expression of PCSK1 mRNA		 CTD PMID:19564919 NCBI chr 5:96,390,333...96,433,248
Ensembl chr 5:96,390,333...96,434,143 		JBrowse link
G PDE8A phosphodiesterase 8A multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of PDE8A mRNA CTD PMID:19564919 NCBI chr15:84,980,467...85,139,142
Ensembl chr15:84,980,440...85,139,145 		JBrowse link
G PDIA4 protein disulfide isomerase family A member 4 multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PDIA4 mRNA] CTD PMID:19564919 NCBI chr 7:149,003,051...149,028,505
Ensembl chr 7:149,003,062...149,028,662 		JBrowse link
G PDK4 pyruvate dehydrogenase kinase 4 multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of PDK4 mRNA
SCH 23390 results in increased expression of PDK4 mRNA		 CTD PMID:19564919 NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516 		JBrowse link
G PEMT phosphatidylethanolamine N-methyltransferase multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of PEMT mRNA
SCH 23390 results in decreased expression of PEMT mRNA		 CTD PMID:19564919 NCBI chr17:17,505,563...17,592,142
Ensembl chr17:17,505,563...17,591,708 		JBrowse link
G PGAP6 post-GPI attachment to proteins 6 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of PGAP6 mRNA CTD PMID:19564919 NCBI chr16:370,788...386,979
Ensembl chr16:370,788...387,113 		JBrowse link
G PIK3R5 phosphoinositide-3-kinase regulatory subunit 5 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of PIK3R5 mRNA CTD PMID:19564919 NCBI chr17:8,878,916...8,965,707
Ensembl chr17:8,878,911...8,965,712 		JBrowse link
G PIK3R6 phosphoinositide-3-kinase regulatory subunit 6 increases expression
multiple interactions		 ISO SCH 23390 results in increased expression of PIK3R6 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of PIK3R6 mRNA		 CTD PMID:19564919 NCBI chr17:8,802,722...8,867,677
Ensembl chr17:8,802,722...8,867,677 		JBrowse link
G PITX3 paired like homeodomain 3 decreases expression
multiple interactions		 ISO SCH 23390 results in decreased expression of PITX3 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of PITX3 mRNA		 CTD PMID:19564919 NCBI chr10:102,230,189...102,241,512
Ensembl chr10:102,230,189...102,241,512 		JBrowse link
G PKP2 plakophilin 2 increases expression
multiple interactions		 ISO SCH 23390 results in increased expression of PKP2 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of PKP2 mRNA		 CTD PMID:19564919 NCBI chr12:32,790,755...32,896,777
Ensembl chr12:32,790,745...32,896,798 		JBrowse link
G PLA1A phospholipase A1 member A multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of PLA1A mRNA CTD PMID:19564919 NCBI chr 3:119,597,885...119,629,811
Ensembl chr 3:119,597,875...119,629,811 		JBrowse link
G PLAGL1 PLAG1 like zinc finger 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of PLAGL1 mRNA CTD PMID:19564919 NCBI chr 6:143,940,300...144,064,599
Ensembl chr 6:143,940,300...144,064,599 		JBrowse link
G PLAT plasminogen activator, tissue type multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of PLAT mRNA
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PLAT mRNA]		 CTD PMID:15659235 PMID:19564919 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709 		JBrowse link
G PLEKHF1 pleckstrin homology and FYVE domain containing 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of PLEKHF1 mRNA CTD PMID:19564919 NCBI chr19:29,665,461...29,675,477
Ensembl chr19:29,665,459...29,675,477 		JBrowse link
G PMCH pro-melanin concentrating hormone multiple interactions
affects expression		 ISO [Methamphetamine co-treated with SCH 23390] affects the expression of PMCH mRNA
SCH 23390 affects the expression of PMCH mRNA		 CTD PMID:19564919 NCBI chr12:102,196,459...102,197,833
Ensembl chr12:102,196,459...102,197,833 		JBrowse link
G PPIP5K2 diphosphoinositol pentakisphosphate kinase 2 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of PPIP5K2 mRNA CTD PMID:19564919 NCBI chr 5:103,120,301...103,212,799
Ensembl chr 5:103,120,149...103,212,799 		JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PPP1R15A mRNA] CTD PMID:19564919 NCBI chr19:48,872,421...48,876,058
Ensembl chr19:48,872,212...48,876,059 		JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PPP3CA protein] CTD PMID:15644446 NCBI chr 4:101,023,418...101,347,526
Ensembl chr 4:101,023,409...101,348,278 		JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PPP3CB protein] CTD PMID:15644446 NCBI chr10:73,436,433...73,496,024
Ensembl chr10:73,436,433...73,496,024 		JBrowse link
G PPP3R2 protein phosphatase 3 regulatory subunit B, beta multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PPP3R2 protein] CTD PMID:15644446 NCBI chr 9:101,591,604...101,594,969
Ensembl chr 9:101,591,604...101,595,021 		JBrowse link
G PRG4 proteoglycan 4 affects expression
multiple interactions		 ISO SCH 23390 affects the expression of PRG4 mRNA
[Methamphetamine co-treated with SCH 23390] affects the expression of PRG4 mRNA		 CTD PMID:19564919 NCBI chr 1:186,296,273...186,314,567
Ensembl chr 1:186,296,279...186,314,567 		JBrowse link
G PRKX protein kinase cAMP-dependent X-linked catalytic subunit increases expression ISO SCH 23390 results in increased expression of PRKX mRNA CTD PMID:19564919 NCBI chr  X:3,604,340...3,713,649
Ensembl chr  X:3,604,340...3,713,649 		JBrowse link
G PROK2 prokineticin 2 multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of PROK2 mRNA
SCH 23390 results in increased expression of PROK2 mRNA		 CTD PMID:19564919 NCBI chr 3:71,771,655...71,785,148
Ensembl chr 3:71,771,655...71,785,206 		JBrowse link
G PROM1 prominin 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of PROM1 mRNA CTD PMID:19564919 NCBI chr 4:15,968,228...16,084,023
Ensembl chr 4:15,963,076...16,084,378 		JBrowse link
G PTH1R parathyroid hormone 1 receptor multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of PTH1R mRNA CTD PMID:19564919 NCBI chr 3:46,877,721...46,903,799
Ensembl chr 3:46,877,721...46,903,799 		JBrowse link
G PYCARD PYD and CARD domain containing multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of PYCARD mRNA
SCH 23390 results in decreased expression of PYCARD mRNA		 CTD PMID:19564919 NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450 		JBrowse link
G RAB3D RAB3D, member RAS oncogene family multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of RAB3D mRNA CTD PMID:19564919 NCBI chr19:11,322,068...11,339,657
Ensembl chr19:11,322,068...11,346,270 		JBrowse link
G RASD1 ras related dexamethasone induced 1 increases expression ISO SCH 23390 results in increased expression of RASD1 mRNA CTD PMID:19564919 NCBI chr17:17,494,437...17,496,395
Ensembl chr17:17,494,437...17,496,395 		JBrowse link
G RASL11A RAS like family 11 member A multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of RASL11A mRNA CTD PMID:19564919 NCBI chr13:27,270,830...27,275,192
Ensembl chr13:27,270,830...27,275,192 		JBrowse link
G RASSF9 Ras association domain family member 9 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of RASSF9 mRNA CTD PMID:19564919 NCBI chr12:85,800,703...85,836,409
Ensembl chr12:85,800,703...85,836,409 		JBrowse link
G RBM3 RNA binding motif protein 3 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of RBM3 mRNA CTD PMID:19564919 NCBI chr  X:48,574,484...48,581,162
Ensembl chr  X:48,574,449...48,581,162 		JBrowse link
G RBM43 RNA binding motif protein 43 decreases expression
multiple interactions		 ISO SCH 23390 results in decreased expression of RBM43 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of RBM43 mRNA		 CTD PMID:19564919 NCBI chr 2:151,247,940...151,261,863
Ensembl chr 2:151,247,940...151,261,863 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO SCH 23390 inhibits the reaction [Cocaine results in increased activity of RELA protein] CTD PMID:19183502 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RGS1 regulator of G protein signaling 1 multiple interactions
affects expression		 ISO [Methamphetamine co-treated with SCH 23390] affects the expression of RGS1 mRNA
SCH 23390 affects the expression of RGS1 mRNA		 CTD PMID:19564919 NCBI chr 1:192,575,773...192,580,024
Ensembl chr 1:192,575,763...192,580,024 		JBrowse link
G RGS2 regulator of G protein signaling 2 multiple interactions ISO SCH 23390 inhibits the reaction [Amphetamine results in increased expression of RGS2 mRNA] CTD PMID:10098858 NCBI chr 1:192,809,039...192,812,275
Ensembl chr 1:192,809,039...192,812,275 		JBrowse link
G RGS4 regulator of G protein signaling 4 affects expression
increases expression
multiple interactions		 ISO SCH 23390 affects the expression of RGS4 protein
SCH 23390 results in increased expression of RGS4 mRNA
Dextroamphetamine promotes the reaction [SCH 23390 results in increased expression of RGS4 mRNA]		 CTD PMID:16539683 NCBI chr 1:163,068,871...163,076,802
Ensembl chr 1:163,068,775...163,076,802 		JBrowse link
G RHBDF1 rhomboid 5 homolog 1 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of RHBDF1 mRNA
SCH 23390 results in decreased expression of RHBDF1 mRNA		 CTD PMID:19564919 NCBI chr16:58,059...76,360
Ensembl chr16:58,059...76,355 		JBrowse link
G RHOD ras homolog family member D multiple interactions ISO [Methamphetamine co-treated with SCH 23390] affects the expression of RHOD mRNA CTD PMID:19564919 NCBI chr11:67,056,847...67,072,017
Ensembl chr11:67,056,847...67,072,017 		JBrowse link
G RIGI RNA sensor RIG-I multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of RIGI mRNA CTD PMID:19564919 NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,348 		JBrowse link
G RIMS2 regulating synaptic membrane exocytosis 2 increases expression
multiple interactions		 ISO SCH 23390 results in increased expression of RIMS2 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of RIMS2 mRNA		 CTD PMID:19564919 NCBI chr 8:103,500,610...104,256,094
Ensembl chr 8:103,500,610...104,254,430 		JBrowse link
G RIPPLY2 ripply transcriptional repressor 2 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of RIPPLY2 mRNA CTD PMID:19564919 NCBI chr 6:83,853,229...83,857,515
Ensembl chr 6:83,853,360...83,857,515 		JBrowse link
G RNF225 ring finger protein 225 decreases expression
multiple interactions		 ISO SCH 23390 results in decreased expression of RNF225 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of RNF225 mRNA		 CTD PMID:19564919 NCBI chr19:58,395,656...58,397,079
Ensembl chr19:58,395,656...58,397,079 		JBrowse link
G RPS6KA5 ribosomal protein S6 kinase A5 multiple interactions ISO SCH 23390 inhibits the reaction [[Oxidopamine co-treated with Levodopa] results in increased expression of RPS6KA5 protein] CTD PMID:19187092 NCBI chr14:90,847,861...91,060,641
Ensembl chr14:90,847,861...91,060,641 		JBrowse link
G RPUSD3 RNA pseudouridine synthase D3 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of RPUSD3 mRNA CTD PMID:19564919 NCBI chr 3:9,837,849...9,844,008
Ensembl chr 3:9,837,849...9,844,602 		JBrowse link
G RTP1 receptor transporter protein 1 multiple interactions
affects expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of RTP1 mRNA
SCH 23390 affects the expression of RTP1 mRNA		 CTD PMID:19564919 NCBI chr 3:187,197,486...187,201,462
Ensembl chr 3:187,197,486...187,201,462 		JBrowse link
G RYR1 ryanodine receptor 1 multiple interactions ISO SCH 23390 inhibits the reaction [SK&F 82958 results in increased expression of RYR1 protein] CTD PMID:22504960 NCBI chr19:38,433,691...38,587,564
Ensembl chr19:38,433,691...38,595,273 		JBrowse link
G RYR2 ryanodine receptor 2 multiple interactions ISO SCH 23390 inhibits the reaction [SK&F 82958 results in increased expression of RYR2 protein] CTD PMID:22504960 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988 		JBrowse link
G S100A11 S100 calcium binding protein A11 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of S100A11 mRNA
SCH 23390 results in decreased expression of S100A11 mRNA		 CTD PMID:19564919 NCBI chr 1:152,032,506...152,037,004
Ensembl chr 1:152,032,506...152,047,907 		JBrowse link
G SERPINB9 serpin family B member 9 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of SERPINB9 mRNA CTD PMID:19564919 NCBI chr 6:2,887,270...2,903,309
Ensembl chr 6:2,887,270...2,903,309 		JBrowse link
G SERTAD1 SERTA domain containing 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of SERTAD1 mRNA CTD PMID:19564919 NCBI chr19:40,421,589...40,425,992
Ensembl chr19:40,421,589...40,425,992 		JBrowse link
G SFRP2 secreted frizzled related protein 2 decreases expression
multiple interactions		 ISO SCH 23390 results in decreased expression of SFRP2 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SFRP2 mRNA		 CTD PMID:19564919 NCBI chr 4:153,780,591...153,789,083
Ensembl chr 4:153,780,591...153,789,083 		JBrowse link
G SGK1 serum/glucocorticoid regulated kinase 1 increases expression
multiple interactions		 ISO SCH 23390 results in increased expression of SGK1 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of SGK1 mRNA		 CTD PMID:19564919 NCBI chr 6:134,169,256...134,318,112
Ensembl chr 6:134,169,248...134,318,112 		JBrowse link
G SIGIRR single Ig and TIR domain containing multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of SIGIRR mRNA CTD PMID:19564919 NCBI chr11:405,716...417,397
Ensembl chr11:405,715...417,455 		JBrowse link
G SIGMAR1 sigma non-opioid intracellular receptor 1 multiple interactions EXP SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; SCH 23390 inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; SCH 23390 inhibits the reaction [SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]]; SCH 23390 inhibits the reaction [SK&F 81297 promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]] CTD PMID:20956312 NCBI chr 9:34,634,722...34,637,787
Ensembl chr 9:34,634,722...34,637,844 		JBrowse link
G SIK1 salt inducible kinase 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of SIK1 mRNA CTD PMID:19564919 NCBI chr21:43,414,483...43,427,131
Ensembl chr21:43,414,483...43,427,131 		JBrowse link
G SIX4 SIX homeobox 4 decreases expression
multiple interactions		 ISO SCH 23390 results in decreased expression of SIX4 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SIX4 mRNA		 CTD PMID:19564919 NCBI chr14:60,709,539...60,724,351
Ensembl chr14:60,709,539...60,724,351 		JBrowse link
G SLC16A11 solute carrier family 16 member 11 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC16A11 mRNA
SCH 23390 results in decreased expression of SLC16A11 mRNA		 CTD PMID:19564919 NCBI chr17:7,041,621...7,044,092
Ensembl chr17:7,041,621...7,044,092 		JBrowse link
G SLC16A13 solute carrier family 16 member 13 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC16A13 mRNA CTD PMID:19564919 NCBI chr17:7,036,015...7,040,117
Ensembl chr17:7,036,015...7,040,117 		JBrowse link
G SLC18A2 solute carrier family 18 member A2 multiple interactions ISO SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in decreased expression of SLC18A2 protein] CTD PMID:30922767 NCBI chr10:117,241,114...117,279,430
Ensembl chr10:117,241,093...117,279,430 		JBrowse link
G SLC22A13 solute carrier family 22 member 13 decreases expression
multiple interactions		 ISO SCH 23390 results in decreased expression of SLC22A13 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC22A13 mRNA		 CTD PMID:19564919 NCBI chr 3:38,265,812...38,278,757
Ensembl chr 3:38,265,812...38,278,757 		JBrowse link
G SLC35B2 solute carrier family 35 member B2 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC35B2 mRNA CTD PMID:19564919 NCBI chr 6:44,254,101...44,257,890
Ensembl chr 6:44,254,096...44,257,890 		JBrowse link
G SLC38A5 solute carrier family 38 member 5 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC38A5 mRNA CTD PMID:19564919 NCBI chr  X:48,458,544...48,470,260
Ensembl chr  X:48,458,537...48,470,260 		JBrowse link
G SLC39A12 solute carrier family 39 member 12 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of SLC39A12 mRNA CTD PMID:19564919 NCBI chr10:17,951,918...18,043,285
Ensembl chr10:17,951,839...18,043,292 		JBrowse link
G SLC40A1 solute carrier family 40 member 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC40A1 mRNA CTD PMID:19564919 NCBI chr 2:189,560,590...189,580,786
Ensembl chr 2:189,560,590...189,583,758 		JBrowse link
G SLC5A3 solute carrier family 5 member 3 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of SLC5A3 mRNA CTD PMID:19564919 NCBI chr21:34,073,578...34,106,260
Ensembl chr21:34,073,578...34,106,260 		JBrowse link
G SLC66A1 solute carrier family 66 member 1 decreases expression
multiple interactions		 ISO SCH 23390 results in decreased expression of SLC66A1 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC66A1 mRNA		 CTD PMID:19564919 NCBI chr 1:19,312,326...19,334,463
Ensembl chr 1:19,312,326...19,329,300 		JBrowse link
G SLC6A13 solute carrier family 6 member 13 decreases expression
multiple interactions		 ISO SCH 23390 results in decreased expression of SLC6A13 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC6A13 mRNA		 CTD PMID:19564919 NCBI chr12:220,622...262,836
Ensembl chr12:220,621...262,873 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 multiple interactions ISO SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in decreased expression of SLC6A3 protein] CTD PMID:30922767 NCBI chr 5:1,392,794...1,445,440
Ensembl chr 5:1,392,794...1,445,440 		JBrowse link
G SMAD3 SMAD family member 3 increases expression
multiple interactions		 ISO SCH 23390 results in increased expression of SMAD3 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of SMAD3 mRNA		 CTD PMID:19564919 NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173 		JBrowse link
G SNX27 sorting nexin 27 multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of SNX27 mRNA alternative form] CTD PMID:12740601 NCBI chr 1:151,612,050...151,699,080
Ensembl chr 1:151,612,006...151,699,091 		JBrowse link
G SOX17 SRY-box transcription factor 17 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of SOX17 mRNA CTD PMID:19564919 NCBI chr 8:54,457,935...54,460,892
Ensembl chr 8:54,457,935...54,460,892 		JBrowse link
G SOX18 SRY-box transcription factor 18 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of SOX18 mRNA CTD PMID:19564919 NCBI chr20:64,047,582...64,049,639
Ensembl chr20:64,047,582...64,049,639 		JBrowse link
G SPACA9 sperm acrosome associated 9 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of SPACA9 mRNA
SCH 23390 results in decreased expression of SPACA9 mRNA		 CTD PMID:19564919 NCBI chr 9:132,878,344...132,890,314
Ensembl chr 9:132,878,027...132,890,201 		JBrowse link
G SPAG8 sperm associated antigen 8 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of SPAG8 mRNA CTD PMID:19564919 NCBI chr 9:35,807,785...35,812,262
Ensembl chr 9:35,808,045...35,812,272 		JBrowse link
G SPATA6L spermatogenesis associated 6 like multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of SPATA6L mRNA CTD PMID:19564919 NCBI chr 9:4,588,821...4,666,480
Ensembl chr 9:4,553,386...4,666,674 		JBrowse link
G ST13 ST13 Hsp70 interacting protein multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ST13 mRNA] CTD PMID:19564919 NCBI chr22:40,824,535...40,856,639
Ensembl chr22:40,824,535...40,856,639 		JBrowse link
G ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of ST8SIA6 mRNA CTD PMID:19564919 NCBI chr10:17,315,421...17,454,595
Ensembl chr10:17,315,421...17,454,595 		JBrowse link
G STEAP1 STEAP family member 1 multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of STEAP1 mRNA
SCH 23390 results in increased expression of STEAP1 mRNA		 CTD PMID:19564919 NCBI chr 7:90,154,469...90,164,827
Ensembl chr 7:90,154,456...90,164,829 		JBrowse link
G STRA6 signaling receptor and transporter of retinol STRA6 affects expression ISO SCH 23390 affects the expression of STRA6 mRNA CTD PMID:19564919 NCBI chr15:74,179,466...74,212,259
Ensembl chr15:74,179,466...74,212,267 		JBrowse link
G SV2C synaptic vesicle glycoprotein 2C increases expression
multiple interactions		 ISO SCH 23390 results in increased expression of SV2C mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of SV2C mRNA		 CTD PMID:19564919 NCBI chr 5:75,847,464...76,353,939
Ensembl chr 5:76,083,383...76,353,939 		JBrowse link
G SWT1 SWT1 RNA endoribonuclease homolog multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of SWT1 mRNA CTD PMID:19564919 NCBI chr 1:185,157,060...185,291,781
Ensembl chr 1:185,157,080...185,291,781 		JBrowse link
G SYT2 synaptotagmin 2 multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] affects the expression of SYT2 mRNA
SCH 23390 results in increased expression of SYT2 mRNA		 CTD PMID:19564919 NCBI chr 1:202,590,596...202,710,454
Ensembl chr 1:202,590,596...202,710,454 		JBrowse link
G TAS1R1 taste 1 receptor member 1 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of TAS1R1 mRNA
SCH 23390 results in decreased expression of TAS1R1 mRNA		 CTD PMID:19564919 NCBI chr 1:6,555,307...6,579,755
Ensembl chr 1:6,555,307...6,579,755 		JBrowse link
G TECTA tectorin alpha multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of TECTA mRNA CTD PMID:19564919 NCBI chr11:121,101,243...121,191,490
Ensembl chr11:121,101,243...121,191,490 		JBrowse link
G TENT5A terminal nucleotidyltransferase 5A multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of TENT5A mRNA CTD PMID:19564919 NCBI chr 6:81,745,730...81,752,681
Ensembl chr 6:81,491,439...81,752,774 		JBrowse link
G TERF1 telomeric repeat binding factor 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of TERF1 mRNA CTD PMID:19564919 NCBI chr 8:73,008,864...73,048,123
Ensembl chr 8:73,008,856...73,048,123 		JBrowse link
G TH tyrosine hydroxylase multiple interactions ISO SCH 23390 inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in decreased expression of TH protein]; SCH 23390 inhibits the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:16088948 PMID:30922767 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G TIE1 tyrosine kinase with immunoglobulin like and EGF like domains 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of TIE1 mRNA CTD PMID:19564919 NCBI chr 1:43,300,982...43,323,108
Ensembl chr 1:43,300,982...43,323,108 		JBrowse link
G TLR2 toll like receptor 2 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of TLR2 mRNA CTD PMID:19564919 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TMEM123 transmembrane protein 123 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of TMEM123 mRNA CTD PMID:19564919 NCBI chr11:102,396,332...102,452,765
Ensembl chr11:102,396,332...102,470,384 		JBrowse link
G TMEM125 transmembrane protein 125 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of TMEM125 mRNA CTD PMID:19564919 NCBI chr 1:43,269,983...43,274,002
Ensembl chr 1:43,269,983...43,274,002 		JBrowse link
G TMEM18 transmembrane protein 18 decreases expression
multiple interactions		 ISO SCH 23390 results in decreased expression of TMEM18 mRNA
[Methamphetamine co-treated with SCH 23390] results in decreased expression of TMEM18 mRNA		 CTD PMID:19564919 NCBI chr 2:663,877...677,406
Ensembl chr 2:663,877...677,406 		JBrowse link
G TMEM252 transmembrane protein 252 multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of TMEM252 mRNA
SCH 23390 results in increased expression of TMEM252 mRNA		 CTD PMID:19564919 NCBI chr 9:68,536,580...68,540,883
Ensembl chr 9:68,536,580...68,540,883 		JBrowse link
G TMTC3 transmembrane O-mannosyltransferase targeting cadherins 3 multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of TMTC3 mRNA
SCH 23390 results in increased expression of TMTC3 mRNA		 CTD PMID:19564919 NCBI chr12:88,142,307...88,199,887
Ensembl chr12:88,142,296...88,199,887 		JBrowse link
G TSC22D3 TSC22 domain family member 3 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of TSC22D3 mRNA CTD PMID:19564919 NCBI chr  X:107,713,221...107,775,988
Ensembl chr  X:107,713,221...107,777,342 		JBrowse link
G TTK TTK protein kinase multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of TTK mRNA CTD PMID:19564919 NCBI chr 6:80,004,649...80,042,527
Ensembl chr 6:80,003,887...80,042,527 		JBrowse link
G TTLL9 tubulin tyrosine ligase like 9 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of TTLL9 mRNA CTD PMID:19564919 NCBI chr20:31,870,634...31,945,000
Ensembl chr20:31,870,634...31,945,000 		JBrowse link
G UBA2 ubiquitin like modifier activating enzyme 2 multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of UBA2 mRNA
SCH 23390 results in increased expression of UBA2 mRNA		 CTD PMID:19564919 NCBI chr19:34,428,381...34,471,251
Ensembl chr19:34,428,352...34,471,251 		JBrowse link
G UGT2B15 UDP glucuronosyltransferase family 2 member B15 increases metabolic processing EXP UGT2B15 protein results in increased metabolism of SCH 23390 CTD PMID:7835232 NCBI chr 4:68,646,597...68,670,652
Ensembl chr 4:68,646,597...68,670,652 		JBrowse link
G UPP1 uridine phosphorylase 1 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of UPP1 mRNA CTD PMID:19564919 NCBI chr 7:48,088,704...48,108,736
Ensembl chr 7:48,088,628...48,108,736 		JBrowse link
G USPL1 ubiquitin specific peptidase like 1 increases expression
multiple interactions		 ISO SCH 23390 results in increased expression of USPL1 mRNA
[Methamphetamine co-treated with SCH 23390] results in increased expression of USPL1 mRNA		 CTD PMID:19564919 NCBI chr13:30,617,920...30,660,766
Ensembl chr13:30,617,693...30,660,770 		JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of VEGFA mRNA] CTD PMID:19564919 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G XBP1 X-box binding protein 1 multiple interactions ISO SCH 23390 inhibits the reaction [Methamphetamine results in increased splicing of XBP1 mRNA] CTD PMID:19564919 NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597 		JBrowse link
G YBX1 Y-box binding protein 1 multiple interactions
increases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of YBX1 mRNA
SCH 23390 results in increased expression of YBX1 mRNA		 CTD PMID:19564919 NCBI chr 1:42,682,418...42,703,805
Ensembl chr 1:42,682,418...42,703,805 		JBrowse link
G ZFP36 ZFP36 ring finger protein multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of ZFP36 mRNA CTD PMID:19564919 NCBI chr19:39,406,847...39,409,407
Ensembl chr19:39,406,847...39,409,407 		JBrowse link
G ZIC2 Zic family member 2 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of ZIC2 mRNA CTD PMID:19564919 NCBI chr13:99,981,784...99,986,765
Ensembl chr13:99,981,784...99,986,765 		JBrowse link
G ZNF189 zinc finger protein 189 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in increased expression of ZFP189 mRNA CTD PMID:19564919 NCBI chr 9:101,398,851...101,410,654
Ensembl chr 9:101,398,851...101,410,660 		JBrowse link
G ZNF287 zinc finger protein 287 multiple interactions
decreases expression		 ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of ZFP287 mRNA
SCH 23390 results in decreased expression of ZFP287 mRNA		 CTD PMID:19564919 NCBI chr17:16,546,954...16,569,212
Ensembl chr17:16,546,954...16,569,204 		JBrowse link
G ZNF688 zinc finger protein 688 multiple interactions ISO [Methamphetamine co-treated with SCH 23390] results in decreased expression of ZFP688 mRNA CTD PMID:19564919 NCBI chr16:30,569,726...30,579,951
Ensembl chr16:30,569,672...30,572,734 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26040
    role 25956
      biological role 25935
        pharmacological role 22059
          antagonist 18984
            dopaminergic antagonist 1652
              SCH 23390 290
Path 2
Term Annotations click to browse term
  CHEBI ontology 26040
    subatomic particle 26015
      composite particle 26015
        hadron 26015
          baryon 26015
            nucleon 26015
              atomic nucleus 26015
                atom 26015
                  main group element atom 25840
                    main group molecular entity 25840
                      s-block molecular entity 25160
                        hydrogen molecular entity 24758
                          hydrides 22970
                            inorganic hydride 20486
                              pnictogen hydride 20427
                                nitrogen hydride 20203
                                  azane 19946
                                    ammonia 19945
                                      organic amino compound 19945
                                        tertiary amino compound 10435
                                          SCH 23390 290
paths to the root