LURAP1 (leucine rich adaptor protein 1) - Rat Genome Database

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Gene: LURAP1 (leucine rich adaptor protein 1) Homo sapiens
Analyze
Symbol: LURAP1
Name: leucine rich adaptor protein 1
RGD ID: 1605156
HGNC Page HGNC:32327
Description: Involved in positive regulation of canonical NF-kappaB signal transduction and positive regulation of cytokine production. Located in cytosol and intracellular membrane-bounded organelle.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C1orf190; FLJ25163; hypothetical protein LOC541468; leucine repeat adapter protein 35A; leucine repeat adaptor protein 35a; LRAP35a; LRP35A; NF-kappa-B activator C1orf190
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38146,203,334 - 46,221,256 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl146,203,334 - 46,221,256 (+)EnsemblGRCh38hg38GRCh38
GRCh37146,669,006 - 46,686,928 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36146,441,593 - 46,459,746 (+)NCBINCBI36Build 36hg18NCBI36
Celera144,956,745 - 44,974,672 (+)NCBICelera
Cytogenetic Map1p34.1NCBI
HuRef144,783,996 - 44,802,228 (+)NCBIHuRef
CHM1_1146,786,144 - 46,804,069 (+)NCBICHM1_1
T2T-CHM13v2.0146,075,666 - 46,098,473 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14702039   PMID:15489334   PMID:16189514   PMID:16710414   PMID:18854160   PMID:21048106   PMID:21873635   PMID:25416956   PMID:25910212   PMID:28514442   PMID:30021884  
PMID:31515488   PMID:32296183   PMID:32814053   PMID:33660365   PMID:33961781   PMID:34525355   PMID:35914814  


Genomics

Comparative Map Data
LURAP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38146,203,334 - 46,221,256 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl146,203,334 - 46,221,256 (+)EnsemblGRCh38hg38GRCh38
GRCh37146,669,006 - 46,686,928 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36146,441,593 - 46,459,746 (+)NCBINCBI36Build 36hg18NCBI36
Celera144,956,745 - 44,974,672 (+)NCBICelera
Cytogenetic Map1p34.1NCBI
HuRef144,783,996 - 44,802,228 (+)NCBIHuRef
CHM1_1146,786,144 - 46,804,069 (+)NCBICHM1_1
T2T-CHM13v2.0146,075,666 - 46,098,473 (+)NCBIT2T-CHM13v2.0
Lurap1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394115,993,925 - 116,001,813 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4115,989,603 - 116,008,535 (-)EnsemblGRCm39 Ensembl
GRCm384116,136,728 - 116,144,616 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4116,132,406 - 116,151,338 (-)EnsemblGRCm38mm10GRCm38
MGSCv374115,809,333 - 115,817,221 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364115,634,623 - 115,642,548 (-)NCBIMGSCv36mm8
Celera4114,874,876 - 114,882,764 (-)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.1NCBI
Lurap1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85134,855,643 - 134,865,366 (-)NCBIGRCr8
mRatBN7.25129,618,926 - 129,628,651 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5129,614,137 - 129,628,766 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5132,235,108 - 132,244,946 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05133,989,695 - 133,999,533 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05134,012,131 - 134,021,969 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05134,991,997 - 135,001,720 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5134,991,997 - 135,001,720 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05138,775,907 - 138,785,616 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45136,414,033 - 136,423,756 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5128,147,570 - 128,157,166 (-)NCBICelera
Cytogenetic Map5q35NCBI
Lurap1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546412,056,588 - 12,072,266 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495546412,056,588 - 12,072,266 (-)NCBIChiLan1.0ChiLan1.0
LURAP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21180,577,178 - 180,602,346 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11179,718,777 - 179,743,933 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0145,508,798 - 45,527,340 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1146,864,060 - 46,881,670 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl146,864,060 - 46,881,670 (+)Ensemblpanpan1.1panPan2
LURAP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11514,156,338 - 14,178,882 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1514,162,087 - 14,173,488 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1514,279,120 - 14,300,752 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01514,309,418 - 14,331,200 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1514,312,749 - 14,325,887 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11514,110,679 - 14,132,274 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01514,179,166 - 14,200,756 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01514,248,643 - 14,270,390 (-)NCBIUU_Cfam_GSD_1.0
Lurap1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505861,417,344 - 61,432,579 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647427,242,077 - 27,252,695 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647427,241,666 - 27,254,405 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LURAP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6165,188,925 - 165,207,730 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16165,187,707 - 165,208,191 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26152,674,047 - 152,687,490 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LURAP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12086,566,427 - 86,583,741 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2086,566,551 - 86,583,175 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603330,403,324 - 30,421,671 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lurap1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249062,133,747 - 2,150,860 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LURAP1
14 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 1p34.3-33(chr1:39479787-47688131)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051817]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051817]|See cases [RCV000051817] Chr1:39479787..47688131 [GRCh38]
Chr1:39945459..48153803 [GRCh37]
Chr1:39718046..47926390 [NCBI36]
Chr1:1p34.3-33		 pathogenic
GRCh38/hg38 1p34.1(chr1:45488251-46220805)x3 copy number gain See cases [RCV000137659] Chr1:45488251..46220805 [GRCh38]
Chr1:45953923..46686477 [GRCh37]
Chr1:45726510..46459064 [NCBI36]
Chr1:1p34.1		 uncertain significance
GRCh38/hg38 1p34.1(chr1:45469848-46220805)x3 copy number gain See cases [RCV000141255] Chr1:45469848..46220805 [GRCh38]
Chr1:45935520..46686477 [GRCh37]
Chr1:45708107..46459064 [NCBI36]
Chr1:1p34.1		 likely benign|uncertain significance
GRCh37/hg19 1p36.12-12(chr1:20608823-120546301)x3 copy number loss not provided [RCV000762767] Chr1:20608823..120546301 [GRCh37]
Chr1:1p36.12-12		 likely benign
GRCh37/hg19 1p34.1(chr1:46078097-46725770)x3 copy number gain See cases [RCV000448110] Chr1:46078097..46725770 [GRCh37]
Chr1:1p34.1		 uncertain significance
GRCh37/hg19 1p34.1-32.3(chr1:45303358-52157856)x1 copy number loss See cases [RCV000448358] Chr1:45303358..52157856 [GRCh37]
Chr1:1p34.1-32.3		 likely pathogenic
NM_001013615.3(LURAP1):c.620A>G (p.Gln207Arg) single nucleotide variant not provided [RCV004715215]|not specified [RCV000455955] Chr1:46220120 [GRCh38]
Chr1:46685792 [GRCh37]
Chr1:1p34.1		 benign
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3 copy number gain See cases [RCV000510383] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p34.1-33(chr1:46541307-47088882)x3 copy number gain See cases [RCV000511609] Chr1:46541307..47088882 [GRCh37]
Chr1:1p34.1-33		 uncertain significance
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684) copy number gain See cases [RCV000510926] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3 copy number gain not provided [RCV000736305] Chr1:82154..249218992 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3 copy number gain not provided [RCV000736295] Chr1:47851..249228449 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p34.1-33(chr1:46372688-47188150)x3 copy number gain not provided [RCV000736482] Chr1:46372688..47188150 [GRCh37]
Chr1:1p34.1-33		 uncertain significance
GRCh37/hg19 1p36.22-21.1(chr1:103343285-103455144)x3 copy number gain Global developmental delay [RCV000787285] Chr1:103343285..103455144 [GRCh37]
Chr1:1p36.22-21.1		 uncertain significance
GRCh37/hg19 1p34.1-33(chr1:46501759-46898503)x3 copy number gain not provided [RCV001005084] Chr1:46501759..46898503 [GRCh37]
Chr1:1p34.1-33		 uncertain significance
NM_001013615.3(LURAP1):c.463G>A (p.Glu155Lys) single nucleotide variant not specified [RCV004302417] Chr1:46219963 [GRCh38]
Chr1:46685635 [GRCh37]
Chr1:1p34.1		 uncertain significance
GRCh37/hg19 1p34.1(chr1:46083531-46738006) copy number gain not specified [RCV002053292] Chr1:46083531..46738006 [GRCh37]
Chr1:1p34.1		 uncertain significance
GRCh37/hg19 1p35.1-33(chr1:33285582-47891811) copy number gain not specified [RCV002052781] Chr1:33285582..47891811 [GRCh37]
Chr1:1p35.1-33		 pathogenic
GRCh37/hg19 1p34.1-32.3(chr1:45303358-52157856) copy number loss not specified [RCV002053281] Chr1:45303358..52157856 [GRCh37]
Chr1:1p34.1-32.3		 likely pathogenic
NC_000001.10:g.(?_46662483)_(46671639_?)del deletion Autosomal recessive limb-girdle muscular dystrophy type 2O [RCV001959106] Chr1:46662483..46671639 [GRCh37]
Chr1:1p34.1		 pathogenic
NM_001013615.3(LURAP1):c.143C>T (p.Ala48Val) single nucleotide variant not specified [RCV004216040] Chr1:46203569 [GRCh38]
Chr1:46669241 [GRCh37]
Chr1:1p34.1		 uncertain significance
NM_001013615.3(LURAP1):c.221T>G (p.Val74Gly) single nucleotide variant not specified [RCV004218619] Chr1:46219721 [GRCh38]
Chr1:46685393 [GRCh37]
Chr1:1p34.1		 uncertain significance
NM_001013615.3(LURAP1):c.460A>G (p.Ser154Gly) single nucleotide variant not specified [RCV004163962] Chr1:46219960 [GRCh38]
Chr1:46685632 [GRCh37]
Chr1:1p34.1		 uncertain significance
NM_001013615.3(LURAP1):c.413G>A (p.Arg138Gln) single nucleotide variant not specified [RCV004226227] Chr1:46219913 [GRCh38]
Chr1:46685585 [GRCh37]
Chr1:1p34.1		 uncertain significance
NM_001013615.3(LURAP1):c.355C>T (p.Pro119Ser) single nucleotide variant not specified [RCV004253796] Chr1:46219855 [GRCh38]
Chr1:46685527 [GRCh37]
Chr1:1p34.1		 uncertain significance
NM_001013615.3(LURAP1):c.430A>C (p.Ile144Leu) single nucleotide variant not specified [RCV004350852] Chr1:46219930 [GRCh38]
Chr1:46685602 [GRCh37]
Chr1:1p34.1		 uncertain significance
Single allele inversion Bilateral polymicrogyria [RCV003459046] Chr1:33246132..61045156 [GRCh38]
Chr1:1p35.1-31.3		 likely pathogenic
NM_001013615.3(LURAP1):c.669C>T (p.Phe223=) single nucleotide variant not provided [RCV003406472] Chr1:46220169 [GRCh38]
Chr1:46685841 [GRCh37]
Chr1:1p34.1		 likely benign
NM_001013615.3(LURAP1):c.127C>A (p.Leu43Met) single nucleotide variant not specified [RCV004410885] Chr1:46203553 [GRCh38]
Chr1:46669225 [GRCh37]
Chr1:1p34.1		 uncertain significance
NM_001013615.3(LURAP1):c.199G>T (p.Ala67Ser) single nucleotide variant not specified [RCV004410886] Chr1:46219699 [GRCh38]
Chr1:46685371 [GRCh37]
Chr1:1p34.1		 uncertain significance
NM_001013615.3(LURAP1):c.289C>T (p.Arg97Trp) single nucleotide variant not specified [RCV004410887] Chr1:46219789 [GRCh38]
Chr1:46685461 [GRCh37]
Chr1:1p34.1		 uncertain significance
NM_001013615.3(LURAP1):c.349G>A (p.Gly117Arg) single nucleotide variant not specified [RCV004410888] Chr1:46219849 [GRCh38]
Chr1:46685521 [GRCh37]
Chr1:1p34.1		 uncertain significance
NM_001013615.3(LURAP1):c.661C>G (p.Leu221Val) single nucleotide variant not specified [RCV004410891] Chr1:46220161 [GRCh38]
Chr1:46685833 [GRCh37]
Chr1:1p34.1		 uncertain significance
NM_001013615.3(LURAP1):c.412C>T (p.Arg138Trp) single nucleotide variant not specified [RCV004640276] Chr1:46219912 [GRCh38]
Chr1:46685584 [GRCh37]
Chr1:1p34.1		 uncertain significance
NM_001013615.3(LURAP1):c.262G>A (p.Glu88Lys) single nucleotide variant not specified [RCV004636329] Chr1:46219762 [GRCh38]
Chr1:46685434 [GRCh37]
Chr1:1p34.1		 uncertain significance
NM_001013615.3(LURAP1):c.38G>T (p.Arg13Leu) single nucleotide variant not specified [RCV004636330] Chr1:46203464 [GRCh38]
Chr1:46669136 [GRCh37]
Chr1:1p34.1		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:563
Count of miRNA genes:427
Interacting mature miRNAs:445
Transcripts:ENST00000371980
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2314561GLUCO47_HGlucose level QTL 47 (human)1.1Glucose level14477336070773360Human
407223054GWAS872030_Hlipid measurement QTL GWAS872030 (human)3e-103lipid measurementblood lipid measurement (CMO:0000050)14620659046206591Human

Markers in Region
L30021  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic MapXq26.3UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map2q33.2UniSTS
Cytogenetic Map1p34UniSTS
Cytogenetic Map12q13.1UniSTS
Cytogenetic Map2q31.2UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map12q24.13UniSTS
Cytogenetic Map8q22.1UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map16p12.3UniSTS
Cytogenetic Map6q21UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2403 2783 2245 4972 1684 2261 6 582 1474 423 2268 6753 5998 51 3734 1 844 1736 1571 174 1

Sequence


Ensembl Acc Id: ENST00000371980   ⟹   ENSP00000361048
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl146,203,334 - 46,221,256 (+)Ensembl
RefSeq Acc Id: NM_001013615   ⟹   NP_001013633
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38146,203,334 - 46,221,256 (+)NCBI
GRCh37146,669,006 - 46,686,928 (+)RGD
Build 36146,441,593 - 46,459,746 (+)NCBI Archive
Celera144,956,745 - 44,974,672 (+)RGD
HuRef144,783,996 - 44,802,228 (+)ENTREZGENE
CHM1_1146,786,144 - 46,804,069 (+)NCBI
T2T-CHM13v2.0146,080,552 - 46,098,473 (+)NCBI
Sequence:
RefSeq Acc Id: XM_054337100   ⟹   XP_054193075
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0146,075,666 - 46,098,473 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001013633 (Get FASTA)   NCBI Sequence Viewer  
  XP_054193075 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH34422 (Get FASTA)   NCBI Sequence Viewer  
  BAB71608 (Get FASTA)   NCBI Sequence Viewer  
  EAX06931 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000361048
  ENSP00000361048.3
GenBank Protein Q96LR2 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001013633   ⟸   NM_001013615
- UniProtKB: Q96LR2 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSP00000361048   ⟸   ENST00000371980
RefSeq Acc Id: XP_054193075   ⟸   XM_054337100
- Peptide Label: isoform X1
- UniProtKB: Q96LR2 (UniProtKB/Swiss-Prot)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q96LR2-F1-model_v2 AlphaFold Q96LR2 1-239 view protein structure

Promoters
RGD ID:6855398
Promoter ID:EPDNEW_H864
Type:initiation region
Name:LURAP1_2
Description:leucine rich adaptor protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H865  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38146,202,915 - 46,202,975EPDNEW
RGD ID:6855400
Promoter ID:EPDNEW_H865
Type:initiation region
Name:LURAP1_1
Description:leucine rich adaptor protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H864  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38146,203,334 - 46,203,394EPDNEW
RGD ID:6784774
Promoter ID:HG_KWN:2548
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562,   Lymphoblastoid
Transcripts:ENST00000307185,   ENST00000371980,   UC001CPK.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36146,441,331 - 46,441,831 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:32327 AgrOrtholog
COSMIC LURAP1 COSMIC
Ensembl Genes ENSG00000171357 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000371980 ENTREZGENE
  ENST00000371980.4 UniProtKB/Swiss-Prot
GTEx ENSG00000171357 GTEx
HGNC ID HGNC:32327 ENTREZGENE
Human Proteome Map LURAP1 Human Proteome Map
InterPro LURA1/LRA25 UniProtKB/Swiss-Prot
  LURAP1 UniProtKB/Swiss-Prot
KEGG Report hsa:541468 UniProtKB/Swiss-Prot
NCBI Gene 541468 ENTREZGENE
OMIM 616129 OMIM
PANTHER LEUCINE RICH ADAPTOR PROTEIN 1 UniProtKB/Swiss-Prot
  PTHR33767 UniProtKB/Swiss-Prot
Pfam LURAP UniProtKB/Swiss-Prot
PharmGKB PA142672401 PharmGKB
UniProt LURA1_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-02-07 LURAP1  leucine rich adaptor protein 1  C1orf190  chromosome 1 open reading frame 190  Symbol and/or name change 5135510 APPROVED