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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:antagonist
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Accession:CHEBI:48706 term browser browse the term
Definition:Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances.
Synonyms:related_synonym: antagonista;   antagoniste;   antagonists



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    Path 1
    Term Annotations click to browse term
      CHEBI ontology 19860
        role 19832
          biological role 19830
            pharmacological role 19069
              antagonist 17251
                AMPA receptor antagonist + 4
                AP-1 antagonist + 9933
                C-X-C chemokine receptor type 4 antagonist + 9
                G-15 0
                G-protein-coupled receptor antagonist + 9
                GABA antagonist + 3876
                GABA-gated chloride channel antagonist + 5322
                IAP antagonist + 2
                IP3 receptor antagonist + 19
                LRH-1 antagonist + 0
                PMX-205 0
                SMO receptor antagonist + 25
                TGFbeta receptor antagonist + 15
                TNP-ATP 3
                adenosine receptor antagonist + 4094
                alpha1B-adrenoceptor antagonist + 0
                aryl hydrocarbon receptor antagonist + 145
                bone morphogenetic protein receptor antagonist + 5694
                bradykinin receptor antagonist + 13
                calcium channel blocker + 7166
                calmodulin antagonist + 81
                cannabinoid receptor antagonist + 455
                capsaicin receptor antagonist + 89
                carbon dioxide 25
                chemokine receptor 2 antagonist + 0
                chemokine receptor 5 antagonist + 43
                dopamine receptor D2 antagonist + 55
                dopaminergic antagonist + 1637
                epidermal growth factor receptor antagonist + 337
                estrogen receptor antagonist + 6180
                excitatory amino acid antagonist + 10770
                fibroblast growth factor receptor antagonist + 49
                glucocorticoid receptor antagonist + 489
                glutamine antagonist + 2
                glycine receptor antagonist + 14
                histamine antagonist + 4893
                hormone antagonist + 13543
                insulin-like growth factor receptor 1 antagonist + 18
                lymphocyte function-associated antigen-1 antagonist + 0
                lysophosphatidic acid receptor antagonist + 0
                melanin-concentrating hormone receptor antagonist + 0
                melatonin receptor antagonist + 19
                metabotropic glutamate receptor antagonist + 39
                neurokinin-1 receptor antagonist + 25
                neurokinin-3 receptor antagonist + 0
                neuropeptide FF receptor antagonist + 0
                neuropeptide Y receptor antagonist + 0
                neuropilin receptor antagonist + 0
                nicotinic acid adenine dinucleotide phosphate receptor antagonist + 0
                odorant receptor antagonist + 6
                opioid receptor antagonist + 107
                orexin receptor antagonist + 4
                platelet glycoprotein-IIb/IIIa receptor antagonist + 7
                platelet-activating factor receptor antagonist + 34
                prostaglandin receptor antagonist + 0
                purinergic receptor P2 antagonist + 126
                retinoic acid receptor antagonist + 43
                sphingosine-1-phosphate receptor antagonist + 20
                substance P receptor antagonist + 25
                thromboxane A2 antagonist + 35
                tropomyosin-related kinase B receptor antagonist + 43
                vascular endothelial growth factor receptor antagonist + 5975
                vitamin B1 antagonist + 0
                vitamin K antagonist + 221
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