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ONTOLOGY REPORT - ANNOTATIONS


Term:antagonist
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Accession:CHEBI:48706 term browser browse the term
Definition:Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances.
Synonyms:related_synonym: antagonista;   antagoniste;   antagonists


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  CHEBI ontology 19779
    role 19727
      biological role 19726
        pharmacological role 18808
          antagonist 16216
            AMPA receptor antagonist + 0
            AP-1 antagonist + 7403
            C-X-C chemokine receptor type 4 antagonist + 0
            C5a receptor antagonist + 0
            G-protein-coupled receptor antagonist + 1
            GABA antagonist + 3490
            IP3 receptor antagonist + 17
            LRH-1 antagonist + 0
            PMX-205 0
            SMO receptor antagonist + 21
            TGFbeta receptor antagonist + 22
            TNP-ATP 0
            adenosine receptor antagonist + 1147
            alpha1B-adrenoceptor antagonist + 0
            aryl hydrocarbon receptor antagonist + 138
            bone morphogenetic protein receptor antagonist + 5650
            bradykinin receptor antagonist + 10
            calmodulin antagonist + 68
            cannabinoid receptor antagonist + 120
            capsaicin receptor antagonist + 67
            carbon dioxide 20
            chemokine receptor 2 antagonist + 0
            chemokine receptor 5 antagonist + 41
            dopamine receptor D2 antagonist + 53
            epidermal growth factor receptor antagonist + 303
            estrogen receptor antagonist + 3429
            excitatory amino acid antagonist + 10088
            fibroblast growth factor receptor antagonist + 25
            glucocorticoid receptor antagonist + 480
            glutamine antagonist + 2
            glycine receptor antagonist + 13
            histamine antagonist + 4603
            hormone antagonist + 11338
            insulin-like growth factor receptor 1 antagonist + 16
            lymphocyte function-associated antigen-1 antagonist + 0
            lysophosphatidic acid receptor antagonist + 0
            melanin-concentrating hormone receptor antagonist + 0
            melatonin receptor antagonist + 14
            metabotropic glutamate receptor antagonist + 29
            neurokinin-1 receptor antagonist + 19
            neurokinin-3 receptor antagonist + 0
            neuropeptide FF receptor antagonist + 0
            neuropeptide Y receptor antagonist + 0
            nicotinic acid adenine dinucleotide phosphate receptor antagonist + 0
            odorant receptor antagonist + 6
            opioid receptor antagonist + 101
            orexin receptor antagonist + 0
            platelet glycoprotein-IIb/IIIa receptor antagonist + 1
            platelet-activating factor receptor antagonist + 24
            prostaglandin receptor antagonist + 0
            protease-activated receptor-1 antagonist + 0
            purinergic receptor P2 antagonist + 113
            retinoic acid receptor antagonist + 42
            sphingosine-1-phosphate receptor antagonist + 0
            substance P receptor antagonist + 19
            thromboxane A2 antagonist + 34
            tropomyosin-related kinase B receptor antagonist + 43
            vascular endothelial growth factor receptor antagonist + 5876
            vitamin B1 antagonist + 0
            vitamin K antagonist + 202
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.