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ONTOLOGY REPORT - ANNOTATIONS


Term:antagonist
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Accession:CHEBI:48706 term browser browse the term
Definition:Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances.
Synonyms:related_synonym: antagonista;   antagoniste;   antagonists


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  CHEBI ontology 19614
    role 19557
      biological role 19550
        pharmacological role 18676
          antagonist 15766
            AMPA receptor antagonist + 0
            AP-1 antagonist + 7254
            G-protein-coupled receptor antagonist + 0
            GABA antagonist + 3329
            IP3 receptor antagonist + 17
            LRH-1 antagonist + 0
            SMO receptor antagonist + 20
            TGFbeta receptor antagonist + 22
            TNP-ATP 0
            adenosine receptor antagonist + 1001
            alpha1B-adrenoceptor antagonist + 0
            aryl hydrocarbon receptor antagonist + 137
            bone morphogenetic protein receptor antagonist + 5639
            bradykinin receptor antagonist + 10
            calmodulin antagonist + 68
            cannabinoid receptor antagonist + 97
            capsaicin receptor antagonist + 67
            carbon dioxide 20
            chemokine receptor 5 antagonist + 35
            dopamine receptor D2 antagonist + 53
            epidermal growth factor receptor antagonist + 286
            estrogen receptor antagonist + 3354
            excitatory amino acid antagonist + 9959
            fibroblast growth factor receptor antagonist + 19
            glucocorticoid receptor antagonist + 66
            glutamine antagonist + 2
            glycine receptor antagonist + 12
            histamine antagonist + 4485
            hormone antagonist + 11269
            insulin-like growth factor receptor 1 antagonist + 16
            lymphocyte function-associated antigen-1 antagonist + 0
            lysophosphatidic acid receptor antagonist + 0
            melanin-concentrating hormone receptor antagonist + 0
            melatonin receptor antagonist + 12
            metabotropic glutamate receptor antagonist + 29
            neurokinin-1 receptor antagonist + 19
            neurokinin-3 receptor antagonist + 0
            neuropeptide FF receptor antagonist + 0
            neuropeptide Y receptor antagonist + 0
            nicotinic acid adenine dinucleotide phosphate receptor antagonist + 0
            odorant receptor antagonist + 6
            opioid receptor antagonist + 100
            orexin receptor antagonist + 0
            platelet glycoprotein-IIb/IIIa receptor antagonist + 1
            platelet-activating factor receptor antagonist + 23
            prostaglandin receptor antagonist + 0
            protease-activated receptor-1 antagonist + 0
            purinergic receptor P2 antagonist + 83
            retinoic acid receptor antagonist + 42
            substance P receptor antagonist + 19
            thromboxane A2 antagonist + 34
            tropomyosin-related kinase B receptor antagonist + 41
            vascular endothelial growth factor receptor antagonist + 214
            vitamin B1 antagonist + 0
            vitamin K antagonist + 198
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.