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Gene: SNX27 (sorting nexin 27) Homo sapiens
Symbol: SNX27
Name: sorting nexin 27
Description: Exhibits phosphatidylinositol-3-phosphate binding activity. Involved in intracellular protein transport and retrograde transport, endosome to plasma membrane. Localizes to several cellular components, including the early endosome; immunological synapse; and nucleoplasm. Colocalizes with the WASH complex and retromer complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: KIAA0488; methamphetamine-responsive transcript 1; MGC126871; MGC126873; MGC20471; MRT1; MY014; sorting nexin family member 27; sorting nexin-27
Mus musculus (house mouse) : Snx27 (sorting nexin family member 27)  MGI  Alliance
Rattus norvegicus (Norway rat) : Snx27 (sorting nexin 27)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Snx27 (sorting nexin 27)
Pan paniscus (bonobo/pygmy chimpanzee) : SNX27 (sorting nexin 27)
Canis lupus familiaris (dog) : SNX27 (sorting nexin 27)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Snx27 (sorting nexin 27)
Sus scrofa (pig) : SNX27 (sorting nexin 27)
Chlorocebus sabaeus (African green monkey) : SNX27 (sorting nexin 27)
Heterocephalus glaber (naked mole-rat) : Snx27 (sorting nexin 27)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1151,612,006 - 151,699,091 (+)EnsemblGRCh38hg38GRCh38
GRCh381151,612,027 - 151,699,080 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371151,584,454 - 151,671,559 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361149,851,286 - 149,938,183 (+)NCBINCBI36hg18NCBI36
Build 341148,397,734 - 148,484,628NCBI
Celera1124,699,311 - 124,786,191 (+)NCBI
Cytogenetic Map1q21.3NCBI
HuRef1122,961,620 - 123,048,521 (+)NCBIHuRef
CHM1_11152,979,810 - 153,066,720 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SNX27
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1349647
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.