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Gene: MPG (N-methylpurine DNA glycosylase) Homo sapiens
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Symbol: MPG
Name: N-methylpurine DNA glycosylase
Description: Predicted to have alkylbase DNA N-glycosylase activity. Predicted to be involved in base-excision repair. Localizes to the cytosol and nucleoplasm; PARTICIPATES IN base excision repair pathway; INTERACTS WITH 1H-imidazo[2,1-i]purine; 2,3,7,8-tetrachlorodibenzodioxine; 3-methyladenine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3' end of the Mid1 gene, localized 68 kb upstream the humanzeta globin gene on 16p; 3-alkyladenine DNA glycosylase; 3-methyladenine DNA glycosidase; AAG; ADPG; alkyladenine DNA glycosylase; anpg; APNG; CRA36.1; CRA36.1 (3-methyl-adenine DNA glycosylase); DNA-3-methyladenine glycosylase; MDG; Mid1; N-methylpurine-DNA glycosylase; N-methylpurine-DNA glycosylase, MPG; PIG11; PIG16; proliferation-inducing protein 11; proliferation-inducing protein 16
Orthologs:
Mus musculus (house mouse) : Mpg (N-methylpurine-DNA glycosylase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mpg (N-methylpurine-DNA glycosylase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mpg (N-methylpurine DNA glycosylase)
Pan paniscus (bonobo/pygmy chimpanzee) : MPG (N-methylpurine DNA glycosylase)
Canis lupus familiaris (dog) : MPG (N-methylpurine DNA glycosylase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mpg (N-methylpurine DNA glycosylase)
Sus scrofa (pig) : MPG (N-methylpurine DNA glycosylase)
Chlorocebus sabaeus (African green monkey) : MPG (N-methylpurine DNA glycosylase)
Heterocephalus glaber (naked mole-rat) : Mpg (N-methylpurine DNA glycosylase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1677,007 - 85,853 (+)Ensembl
GRCh381677,019 - 85,851 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3716127,018 - 135,850 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361667,018 - 75,845 (+)NCBINCBI36hg18NCBI36
Build 341669,146 - 75,841NCBI
Celera16328,909 - 337,375 (+)NCBI
Cytogenetic Map16p13.3NCBI
HuRef1645,422 - 54,310 (+)NCBIHuRef
CHM1_116126,965 - 135,796 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MPG
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731894
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.