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Gene: CA4 (carbonic anhydrase 4) Homo sapiens
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Symbol: CA4
Name: carbonic anhydrase 4
Description: Predicted to have carbonate dehydratase activity and zinc ion binding activity. Involved in bicarbonate transport. Localizes to several cellular components, including anchored component of external side of plasma membrane; brush border membrane; and cytoplasmic vesicle membrane. Implicated in retinitis pigmentosa and retinitis pigmentosa 17.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CA-IV; CAIV; Car4; carbonate dehydratase IV; carbonic anhydrase IV; carbonic dehydratase IV; retinitis pigmentosa 17 (autosomal dominant); RP17
Orthologs:
Mus musculus (house mouse) : Car4 (carbonic anhydrase 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ca4 (carbonic anhydrase 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ca4 (carbonic anhydrase 4)
Pan paniscus (bonobo/pygmy chimpanzee) : CA4 (carbonic anhydrase 4)
Canis lupus familiaris (dog) : CA4 (carbonic anhydrase 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ca4 (carbonic anhydrase 4)
Sus scrofa (pig) : CA4 (carbonic anhydrase 4)
Chlorocebus sabaeus (African green monkey) : CA4 (carbonic anhydrase 4)
Heterocephalus glaber (naked mole-rat) : Ca4 (carbonic anhydrase 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1760,149,942 - 60,170,899 (+)EnsemblGRCh38hg38GRCh38
GRCh381760,149,942 - 60,179,021 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371758,227,302 - 58,236,907 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361755,582,131 - 55,591,686 (+)NCBINCBI36hg18NCBI36
Build 341755,582,130 - 55,591,686NCBI
Celera1754,687,198 - 54,696,791 (+)NCBI
Cytogenetic Map17q23.1NCBI
HuRef1753,598,240 - 53,607,844 (+)NCBIHuRef
CHM1_11758,291,334 - 58,300,936 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CA4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1353429
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.