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Gene: SLC5A3 (solute carrier family 5 member 3) Homo sapiens
Symbol: SLC5A3
Name: solute carrier family 5 member 3
RGD ID: 734339
Description: Exhibits ion channel binding activity and potassium channel regulator activity. Predicted to be involved in several processes, including monosaccharide transmembrane transport; myo-inositol import across plasma membrane; and positive regulation of reactive oxygen species biosynthetic process. Localizes to perinuclear region of cytoplasm and plasma membrane; INTERACTS WITH (-)-epigallocatechin 3-gallate; aflatoxin M1; amiodarone.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BCW2; human solute carrier family 5, member 3, Sodium/myo-inositol cotransporter; Na(+)/myo-inositol cotransporter; SMIT; SMIT1; SMIT2; sodium/myo-inositol cotransporter; sodium/myo-inositol cotransporter 1; sodium/myo-inositol transporter 1; solute carrier family 5 (inositol transporter), member 3; solute carrier family 5 (inositol transporters), member 3; solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
Mus musculus (house mouse) : Slc5a3 (solute carrier family 5 (inositol transporters), member 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Slc5a3 (solute carrier family 5 member 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Slc5a3 (solute carrier family 5 member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SLC5A3 (solute carrier family 5 member 3)
Canis lupus familiaris (dog) : SLC5A3 (solute carrier family 5 member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc5a3 (solute carrier family 5 member 3)
Sus scrofa (pig) : SLC5A3 (solute carrier family 5 member 3)
Chlorocebus sabaeus (African green monkey) : SLC5A3 (solute carrier family 5 member 3)
Heterocephalus glaber (naked mole-rat) : Slc5a3 (solute carrier family 5 member 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2134,073,578 - 34,106,260 (+)EnsemblGRCh38hg38GRCh38
GRCh382134,073,578 - 34,106,260 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372135,445,503 - 35,515,334 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362134,367,740 - 34,400,431 (+)NCBINCBI36hg18NCBI36
Build 342134,389,367 - 34,391,524NCBI
Celera2120,645,433 - 20,678,122 (+)NCBI
Cytogenetic Map21q22.11NCBI
HuRef2120,945,609 - 20,957,018 (+)NCBIHuRef
CHM1_12135,008,095 - 35,040,833 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SLC5A3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 734339
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.