CNOT6L (CCR4-NOT transcription complex subunit 6 like) - Rat Genome Database

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Gene: CNOT6L (CCR4-NOT transcription complex subunit 6 like) Homo sapiens
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Symbol: CNOT6L
Name: CCR4-NOT transcription complex subunit 6 like
RGD ID: 1319296
HGNC Page HGNC:18042
Description: Predicted to enable poly(A)-specific ribonuclease activity. Involved in positive regulation of cell population proliferation and positive regulation of cytoplasmic mRNA processing body assembly. Located in cytosol and nucleus. Part of CCR4-NOT complex.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: carbon catabolite repressor protein 4 homolog B; CCR4-NOT transcription complex subunit 6-like; CCR4-NOT transcription complex, subunit 6-like; CCR4b
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: CNOT6LP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38477,713,387 - 77,820,269 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl477,713,387 - 77,819,615 (-)EnsemblGRCh38hg38GRCh38
GRCh37478,634,541 - 78,741,423 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36478,853,565 - 78,959,568 (-)NCBINCBI36Build 36hg18NCBI36
Build 34479,004,337 - 79,097,701NCBI
Celera475,935,929 - 76,042,004 (-)NCBICelera
Cytogenetic Map4q21.1NCBI
HuRef474,386,458 - 74,492,461 (-)NCBIHuRef
CHM1_1478,611,478 - 78,717,345 (-)NCBICHM1_1
T2T-CHM13v2.0481,054,227 - 81,161,055 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
CCR4-NOT complex  (IDA,NAS)
cytoplasm  (IDA,IEA)
cytosol  (IDA,TAS)
nucleus  (IDA,IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
2. RNA decay machines: deadenylation by the Ccr4-not and Pan2-Pan3 complexes. Wahle E and Winkler GS, Biochim Biophys Acta. 2013 Jun-Jul;1829(6-7):561-70. doi: 10.1016/j.bbagrm.2013.01.003. Epub 2013 Jan 19.
Additional References at PubMed
PMID:14702039   PMID:16344560   PMID:17353931   PMID:17452450   PMID:18377426   PMID:19558367   PMID:20211142   PMID:20360068   PMID:20379614   PMID:20628353   PMID:20818722   PMID:21078877  
PMID:21233283   PMID:21873635   PMID:21981923   PMID:21984185   PMID:22977175   PMID:23591815   PMID:23663784   PMID:24057671   PMID:26170170   PMID:26186194   PMID:26496610   PMID:26608607  
PMID:27013054   PMID:27173435   PMID:28514442   PMID:29395067   PMID:29507755   PMID:29509190   PMID:30833792   PMID:30926667   PMID:30984545   PMID:31116665   PMID:31320642   PMID:31527615  
PMID:31586073   PMID:32296183   PMID:32707033   PMID:33961781   PMID:34611029   PMID:34672954   PMID:34887419   PMID:35271311   PMID:35385705   PMID:35545034   PMID:37531026  


Genomics

Comparative Map Data
CNOT6L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38477,713,387 - 77,820,269 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl477,713,387 - 77,819,615 (-)EnsemblGRCh38hg38GRCh38
GRCh37478,634,541 - 78,741,423 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36478,853,565 - 78,959,568 (-)NCBINCBI36Build 36hg18NCBI36
Build 34479,004,337 - 79,097,701NCBI
Celera475,935,929 - 76,042,004 (-)NCBICelera
Cytogenetic Map4q21.1NCBI
HuRef474,386,458 - 74,492,461 (-)NCBIHuRef
CHM1_1478,611,478 - 78,717,345 (-)NCBICHM1_1
T2T-CHM13v2.0481,054,227 - 81,161,055 (-)NCBIT2T-CHM13v2.0
Cnot6l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39596,218,192 - 96,312,044 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl596,218,192 - 96,312,030 (-)EnsemblGRCm39 Ensembl
GRCm38596,070,333 - 96,164,198 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl596,070,333 - 96,164,171 (-)EnsemblGRCm38mm10GRCm38
MGSCv37596,504,756 - 96,591,009 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36596,315,891 - 96,402,292 (-)NCBIMGSCv36mm8
Celera593,419,034 - 93,505,443 (-)NCBICelera
Cytogenetic Map5E3NCBI
cM Map547.29NCBI
Cnot6l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81413,714,475 - 13,806,481 (+)NCBIGRCr8
mRatBN7.21413,410,499 - 13,502,511 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1413,411,281 - 13,498,203 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1413,379,451 - 13,466,326 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01414,679,308 - 14,766,183 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01413,395,794 - 13,482,664 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01415,059,101 - 15,148,255 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1415,059,387 - 15,146,586 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01415,000,591 - 15,089,212 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41414,924,620 - 15,011,984 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11414,877,885 - 15,010,870 (+)NCBI
Celera1413,458,539 - 13,545,193 (+)NCBICelera
Cytogenetic Map14p22NCBI
Cnot6l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554332,213,444 - 2,316,049 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554332,206,462 - 2,290,773 (-)NCBIChiLan1.0ChiLan1.0
CNOT6L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2352,244,754 - 52,353,101 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1452,431,326 - 52,539,612 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0446,374,255 - 46,482,552 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1452,220,159 - 52,327,311 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl452,263,010 - 52,320,307 (+)Ensemblpanpan1.1panPan2
CNOT6L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1322,192,800 - 2,305,526 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl322,145,813 - 2,306,229 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3239,584,726 - 39,698,628 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0322,218,607 - 2,332,531 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl322,171,626 - 2,332,326 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1322,217,455 - 2,331,474 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0322,165,687 - 2,279,692 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03237,893,391 - 38,007,445 (+)NCBIUU_Cfam_GSD_1.0
Cnot6l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528510,004,724 - 10,105,815 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366761,408,048 - 1,502,519 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366761,401,428 - 1,474,167 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CNOT6L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl873,185,999 - 73,335,741 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1873,191,721 - 73,335,779 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2877,392,505 - 77,496,997 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CNOT6L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1726,210,368 - 26,312,938 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl726,217,371 - 26,312,567 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660374,562,902 - 4,666,026 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cnot6l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475713,219,267 - 13,340,955 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475713,218,464 - 13,346,404 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CNOT6L
20 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 4q21.1-21.23(chr4:75453111-84094295)x1 copy number loss See cases [RCV000050786] Chr4:75453111..84094295 [GRCh38]
Chr4:76378321..85015448 [GRCh37]
Chr4:76597345..85234472 [NCBI36]
Chr4:4q21.1-21.23
pathogenic
GRCh38/hg38 4q13.3-21.21(chr4:71128874-78099088)x3 copy number gain See cases [RCV000051774] Chr4:71128874..78099088 [GRCh38]
Chr4:71994591..79020242 [GRCh37]
Chr4:72213455..79239266 [NCBI36]
Chr4:4q13.3-21.21
pathogenic
GRCh38/hg38 4q12-22.3(chr4:51831622-97505618)x3 copy number gain See cases [RCV000051772] Chr4:51831622..97505618 [GRCh38]
Chr4:52697788..98426769 [GRCh37]
Chr4:52392545..98645792 [NCBI36]
Chr4:4q12-22.3
pathogenic
GRCh38/hg38 4q13.2-21.23(chr4:67869564-85517308)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053294]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053294]|See cases [RCV000053294] Chr4:67869564..85517308 [GRCh38]
Chr4:68735282..86438461 [GRCh37]
Chr4:68417877..86657485 [NCBI36]
Chr4:4q13.2-21.23
pathogenic
GRCh38/hg38 4q13.3-21.22(chr4:71079179-81802208)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053295]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053295]|See cases [RCV000053295] Chr4:71079179..81802208 [GRCh38]
Chr4:71944896..82723361 [GRCh37]
Chr4:72163760..82942385 [NCBI36]
Chr4:4q13.3-21.22
pathogenic
GRCh38/hg38 4q13.3-22.1(chr4:74031395-90421127)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053296]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053296]|See cases [RCV000053296] Chr4:74031395..90421127 [GRCh38]
Chr4:74897112..91342278 [GRCh37]
Chr4:75115976..91561301 [NCBI36]
Chr4:4q13.3-22.1
pathogenic
GRCh38/hg38 4q13.3-21.3(chr4:72262258-86002147)x3 copy number gain See cases [RCV000138312] Chr4:72262258..86002147 [GRCh38]
Chr4:73127975..86923300 [GRCh37]
Chr4:73346839..87142324 [NCBI36]
Chr4:4q13.3-21.3
pathogenic
GRCh38/hg38 4q21.1-21.21(chr4:75801143-79005805)x3 copy number gain See cases [RCV000141486] Chr4:75801143..79005805 [GRCh38]
Chr4:76722296..79926959 [GRCh37]
Chr4:76941320..80145983 [NCBI36]
Chr4:4q21.1-21.21
pathogenic
GRCh38/hg38 4q13.2-22.3(chr4:68686088-95294456)x3 copy number gain See cases [RCV000143458] Chr4:68686088..95294456 [GRCh38]
Chr4:69551806..96215607 [GRCh37]
Chr4:69234401..96434630 [NCBI36]
Chr4:4q13.2-22.3
pathogenic
NM_144571.3(CNOT6L):c.1201A>C (p.Asn401His) single nucleotide variant not specified [RCV004291920] Chr4:77728905 [GRCh38]
Chr4:78650059 [GRCh37]
Chr4:4q21.1
uncertain significance
GRCh37/hg19 4q21.1-21.21(chr4:78671333-79679677)x3 copy number gain See cases [RCV000447315] Chr4:78671333..79679677 [GRCh37]
Chr4:4q21.1-21.21
uncertain significance
GRCh37/hg19 4p16.3-q35.2(chr4:12440-190904441)x3 copy number gain See cases [RCV000446653] Chr4:12440..190904441 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473) copy number gain See cases [RCV000510453] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
NM_144571.3(CNOT6L):c.1619C>A (p.Pro540His) single nucleotide variant not specified [RCV004331181] Chr4:77720480 [GRCh38]
Chr4:78641634 [GRCh37]
Chr4:4q21.1
uncertain significance
GRCh37/hg19 4p16.3-q35.2(chr4:68346-190957473)x3 copy number gain See cases [RCV000512241] Chr4:68346..190957473 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4q21.1(chr4:78739968-78740287)x1 copy number loss not provided [RCV000743719] Chr4:78739968..78740287 [GRCh37]
Chr4:4q21.1
benign
GRCh37/hg19 4q21.1(chr4:78739968-78740341)x1 copy number loss not provided [RCV000743720] Chr4:78739968..78740341 [GRCh37]
Chr4:4q21.1
benign
GRCh37/hg19 4q21.1(chr4:78739977-78740287)x0 copy number loss not provided [RCV000743721] Chr4:78739977..78740287 [GRCh37]
Chr4:4q21.1
benign
GRCh37/hg19 4q21.1(chr4:78739977-78740341)x1 copy number loss not provided [RCV000743722] Chr4:78739977..78740341 [GRCh37]
Chr4:4q21.1
benign
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190963766)x3 copy number gain not provided [RCV000743156] Chr4:49450..190963766 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:11525-191028879)x3 copy number gain not provided [RCV000743147] Chr4:11525..191028879 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
GRCh37/hg19 4p16.3-q35.2(chr4:49450-190915650)x3 copy number gain not provided [RCV000743155] Chr4:49450..190915650 [GRCh37]
Chr4:4p16.3-q35.2
pathogenic
NM_144571.3(CNOT6L):c.1420T>C (p.Leu474=) single nucleotide variant not provided [RCV000924620] Chr4:77726202 [GRCh38]
Chr4:78647356 [GRCh37]
Chr4:4q21.1
likely benign
GRCh37/hg19 4q13.3-21.23(chr4:72680879-86426232)x1 copy number loss not provided [RCV001005556] Chr4:72680879..86426232 [GRCh37]
Chr4:4q13.3-21.23
pathogenic
GRCh37/hg19 4q13.2-21.21(chr4:68950363-79738598)x1 copy number loss not provided [RCV001005553] Chr4:68950363..79738598 [GRCh37]
Chr4:4q13.2-21.21
pathogenic
GRCh37/hg19 4q21.1(chr4:78112981-78742412)x3 copy number gain not provided [RCV000846655] Chr4:78112981..78742412 [GRCh37]
Chr4:4q21.1
uncertain significance
GRCh37/hg19 4q13.2-21.22(chr4:68242784-82991431)x3 copy number gain not provided [RCV000845944] Chr4:68242784..82991431 [GRCh37]
Chr4:4q13.2-21.22
pathogenic
GRCh37/hg19 4q13.3-21.3(chr4:71412409-87920784)x1 copy number loss See cases [RCV001263040] Chr4:71412409..87920784 [GRCh37]
Chr4:4q13.3-21.3
pathogenic
GRCh37/hg19 4q12-31.21(chr4:52866944-143582507)x3 copy number gain not provided [RCV001827738] Chr4:52866944..143582507 [GRCh37]
Chr4:4q12-31.21
pathogenic
GRCh37/hg19 4q21.1-21.21(chr4:78671333-79679677) copy number gain not specified [RCV002053431] Chr4:78671333..79679677 [GRCh37]
Chr4:4q21.1-21.21
uncertain significance
GRCh37/hg19 4q13.3-21.21(chr4:73055313-80083154) copy number loss not specified [RCV002053427] Chr4:73055313..80083154 [GRCh37]
Chr4:4q13.3-21.21
pathogenic
GRCh37/hg19 4q13.3-22.1(chr4:75737340-91131156) copy number gain not specified [RCV002053429] Chr4:75737340..91131156 [GRCh37]
Chr4:4q13.3-22.1
pathogenic
NC_000004.12:g.67833055_82716065del deletion See cases [RCV003313802] Chr4:67833055..82716065 [GRCh38]
Chr4:4q13.2-21.22
pathogenic
GRCh37/hg19 4q21.1(chr4:78117589-78749042)x3 copy number gain not provided [RCV002474675] Chr4:78117589..78749042 [GRCh37]
Chr4:4q21.1
uncertain significance
NM_144571.3(CNOT6L):c.779A>C (p.Asp260Ala) single nucleotide variant not specified [RCV004165545] Chr4:77742234 [GRCh38]
Chr4:78663388 [GRCh37]
Chr4:4q21.1
uncertain significance
NM_144571.3(CNOT6L):c.539G>A (p.Arg180Gln) single nucleotide variant not specified [RCV004195654] Chr4:77748336 [GRCh38]
Chr4:78669490 [GRCh37]
Chr4:4q21.1
uncertain significance
NM_144571.3(CNOT6L):c.1334T>C (p.Met445Thr) single nucleotide variant not specified [RCV004191642] Chr4:77726288 [GRCh38]
Chr4:78647442 [GRCh37]
Chr4:4q21.1
uncertain significance
NM_144571.3(CNOT6L):c.160T>G (p.Ser54Ala) single nucleotide variant not specified [RCV004226808] Chr4:77774684 [GRCh38]
Chr4:78695838 [GRCh37]
Chr4:4q21.1
uncertain significance
NM_144571.3(CNOT6L):c.140G>A (p.Ser47Asn) single nucleotide variant not specified [RCV004132975] Chr4:77774704 [GRCh38]
Chr4:78695858 [GRCh37]
Chr4:4q21.1
uncertain significance
NM_144571.3(CNOT6L):c.89A>C (p.Asn30Thr) single nucleotide variant not specified [RCV004073651] Chr4:77776309 [GRCh38]
Chr4:78697463 [GRCh37]
Chr4:4q21.1
uncertain significance
NM_144571.3(CNOT6L):c.554C>T (p.Pro185Leu) single nucleotide variant not specified [RCV004085346] Chr4:77748321 [GRCh38]
Chr4:78669475 [GRCh37]
Chr4:4q21.1
uncertain significance
NM_144571.3(CNOT6L):c.1349A>G (p.Asn450Ser) single nucleotide variant not specified [RCV004159471] Chr4:77726273 [GRCh38]
Chr4:78647427 [GRCh37]
Chr4:4q21.1
uncertain significance
NM_144571.3(CNOT6L):c.1547A>G (p.Asn516Ser) single nucleotide variant not specified [RCV004182514] Chr4:77720552 [GRCh38]
Chr4:78641706 [GRCh37]
Chr4:4q21.1
uncertain significance
NM_144571.3(CNOT6L):c.428A>G (p.Asn143Ser) single nucleotide variant not specified [RCV004069485] Chr4:77756924 [GRCh38]
Chr4:78678078 [GRCh37]
Chr4:4q21.1
uncertain significance
NM_144571.3(CNOT6L):c.179C>T (p.Ala60Val) single nucleotide variant not specified [RCV004190179] Chr4:77774665 [GRCh38]
Chr4:78695819 [GRCh37]
Chr4:4q21.1
uncertain significance
NM_144571.3(CNOT6L):c.1526C>G (p.Pro509Arg) single nucleotide variant not specified [RCV004252713] Chr4:77720573 [GRCh38]
Chr4:78641727 [GRCh37]
Chr4:4q21.1
uncertain significance
NM_144571.3(CNOT6L):c.1657A>G (p.Asn553Asp) single nucleotide variant not specified [RCV004282668] Chr4:77720442 [GRCh38]
Chr4:78641596 [GRCh37]
Chr4:4q21.1
uncertain significance
GRCh37/hg19 4q13.3-21.21(chr4:74822261-79345650)x1 copy number loss not specified [RCV003986507] Chr4:74822261..79345650 [GRCh37]
Chr4:4q13.3-21.21
uncertain significance
NM_144571.3(CNOT6L):c.1540G>C (p.Glu514Gln) single nucleotide variant not specified [RCV004442006] Chr4:77720559 [GRCh38]
Chr4:78641713 [GRCh37]
Chr4:4q21.1
uncertain significance
NM_144571.3(CNOT6L):c.1660C>T (p.Arg554Trp) single nucleotide variant not specified [RCV004442007] Chr4:77720439 [GRCh38]
Chr4:78641593 [GRCh37]
Chr4:4q21.1
uncertain significance
GRCh37/hg19 4p12-q35.2(chr4:45455621-191003541)x3 copy number gain not provided [RCV003885507] Chr4:45455621..191003541 [GRCh37]
Chr4:4p12-q35.2
pathogenic
NM_144571.3(CNOT6L):c.209G>A (p.Arg70His) single nucleotide variant not specified [RCV004615503] Chr4:77774635 [GRCh38]
Chr4:78695789 [GRCh37]
Chr4:4q21.1
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:7131
Count of miRNA genes:1283
Interacting mature miRNAs:1661
Transcripts:ENST00000264903, ENST00000504123, ENST00000504804, ENST00000505983, ENST00000506166, ENST00000508371, ENST00000512485, ENST00000515441, ENST00000515506
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
597034262GWAS1130336_Hbrain volume measurement QTL GWAS1130336 (human)2e-10brain volume measurementbrain morphological measurement (CMO:0000136)47779427877794279Human
406916356GWAS565332_Hbrain volume measurement QTL GWAS565332 (human)5e-09brain volume measurementbrain morphological measurement (CMO:0000136)47779427877794279Human
597323939GWAS1420013_Hpantothenate measurement QTL GWAS1420013 (human)0.0000003pantothenate measurement47778324177783242Human
406916363GWAS565339_Hbrain volume measurement QTL GWAS565339 (human)1e-08brain volume measurementbrain morphological measurement (CMO:0000136)47779411077794111Human
597180197GWAS1276271_Heducational attainment QTL GWAS1276271 (human)8e-13educational attainment47772123577721236Human
597341828GWAS1437902_HC-X-C motif chemokine 10 measurement QTL GWAS1437902 (human)3e-16C-X-C motif chemokine 10 measurement47773348177733482Human
597034280GWAS1130354_Hbrain volume measurement QTL GWAS1130354 (human)8e-11brain volume measurementbrain morphological measurement (CMO:0000136)47780754377807544Human

Markers in Region
SHGC-24218  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37478,665,155 - 78,665,339UniSTSGRCh37
Build 36478,884,179 - 78,884,363RGDNCBI36
Celera475,966,505 - 75,966,689RGD
Cytogenetic Map4q13.3UniSTS
HuRef474,417,019 - 74,417,203UniSTS
SHGC4-1546  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37478,636,594 - 78,636,775UniSTSGRCh37
Build 36478,855,618 - 78,855,799RGDNCBI36
Celera475,937,959 - 75,938,140RGD
Cytogenetic Map4q13.3UniSTS
HuRef474,388,488 - 74,388,669UniSTS
SHGC-111263  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37478,667,030 - 78,667,309UniSTSGRCh37
Build 36478,886,054 - 78,886,333RGDNCBI36
Celera475,968,380 - 75,968,659RGD
Cytogenetic Map4q13.3UniSTS
HuRef474,418,894 - 74,419,173UniSTS
SHGC-111937  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37478,691,341 - 78,691,633UniSTSGRCh37
Build 36478,910,365 - 78,910,657RGDNCBI36
Celera475,992,690 - 75,992,982RGD
Cytogenetic Map4q13.3UniSTS
HuRef474,443,172 - 74,443,464UniSTS
D4S895  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37478,665,152 - 78,665,444UniSTSGRCh37
Build 36478,884,176 - 78,884,468RGDNCBI36
Celera475,966,502 - 75,966,794RGD
Cytogenetic Map4q13.3UniSTS
HuRef474,417,016 - 74,417,308UniSTS
TNG Radiation Hybrid Map445616.0UniSTS
G33447  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37478,636,676 - 78,636,923UniSTSGRCh37
Build 36478,855,700 - 78,855,947RGDNCBI36
Celera475,938,041 - 75,938,288RGD
Cytogenetic Map4q13.3UniSTS
HuRef474,388,570 - 74,388,817UniSTS
CNOT6L_8159  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37478,646,976 - 78,647,462UniSTSGRCh37
Build 36478,866,000 - 78,866,486RGDNCBI36
Celera475,948,341 - 75,948,827RGD
HuRef474,398,870 - 74,399,356UniSTS
D4S623E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37478,636,603 - 78,636,751UniSTSGRCh37
Build 36478,855,627 - 78,855,775RGDNCBI36
Celera475,937,968 - 75,938,116RGD
Cytogenetic Map4q13.3UniSTS
HuRef474,388,497 - 74,388,645UniSTS
SHGC-36234  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37478,635,255 - 78,635,367UniSTSGRCh37
Build 36478,854,279 - 78,854,391RGDNCBI36
Celera475,936,643 - 75,936,755RGD
Cytogenetic Map4q13.3UniSTS
HuRef474,387,172 - 74,387,284UniSTS
GeneMap99-G3 RH Map44361.0UniSTS
A006V35  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37478,635,242 - 78,635,348UniSTSGRCh37
Build 36478,854,266 - 78,854,372RGDNCBI36
Celera475,936,630 - 75,936,736RGD
Cytogenetic Map4q13.3UniSTS
HuRef474,387,159 - 74,387,265UniSTS
GeneMap99-GB4 RH Map4449.65UniSTS
G34328  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37478,638,034 - 78,638,372UniSTSGRCh37
Build 36478,857,058 - 78,857,396RGDNCBI36
Celera475,939,398 - 75,939,736RGD
Cytogenetic Map4q13.3UniSTS
HuRef474,389,927 - 74,390,265UniSTS
UniSTS:235228  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371556,296,063 - 56,296,309UniSTSGRCh37
GRCh37478,639,740 - 78,639,986UniSTSGRCh37
Build 36478,858,764 - 78,859,010RGDNCBI36
Celera475,941,105 - 75,941,351RGD
HuRef1533,120,017 - 33,120,263UniSTS
HuRef474,391,634 - 74,391,880UniSTS
CNOT6L  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37478,652,563 - 78,652,663UniSTSGRCh37
GRCh371556,298,574 - 56,298,674UniSTSGRCh37
Celera475,953,928 - 75,954,028UniSTS
Celera1533,187,352 - 33,187,452UniSTS
HuRef1533,122,528 - 33,122,628UniSTS
HuRef474,404,444 - 74,404,544UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2436 2788 2249 4963 1725 2351 5 623 1951 465 2268 7296 6465 53 3725 851 1741 1616 173 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001286790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001365006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001365007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387837 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001387843 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_144571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011531806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011531807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011531808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011531809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017007957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047449962 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047449963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054349499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054349500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054349501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054349502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054349503 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054349504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054349505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC104701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK027214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK058188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK124855 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK304397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL133112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA043791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB454180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000504123   ⟹   ENSP00000424896
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl477,713,387 - 77,819,368 (-)Ensembl
Ensembl Acc Id: ENST00000504804   ⟹   ENSP00000425836
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl477,720,238 - 77,819,376 (-)Ensembl
Ensembl Acc Id: ENST00000505983
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl477,726,166 - 77,742,472 (-)Ensembl
Ensembl Acc Id: ENST00000506166
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl477,742,203 - 77,819,366 (-)Ensembl
Ensembl Acc Id: ENST00000508371
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl477,728,877 - 77,731,881 (-)Ensembl
Ensembl Acc Id: ENST00000512485   ⟹   ENSP00000425571
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl477,720,230 - 77,819,615 (-)Ensembl
Ensembl Acc Id: ENST00000515441   ⟹   ENSP00000426269
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl477,756,862 - 77,819,390 (-)Ensembl
Ensembl Acc Id: ENST00000515506   ⟹   ENSP00000423750
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl477,718,021 - 77,819,063 (-)Ensembl
Ensembl Acc Id: ENST00000649644   ⟹   ENSP00000497467
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl477,713,387 - 77,819,368 (-)Ensembl
RefSeq Acc Id: NM_001286790   ⟹   NP_001273719
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,713,387 - 77,819,368 (-)NCBI
HuRef474,386,458 - 74,492,461 (-)NCBI
CHM1_1478,611,478 - 78,717,345 (-)NCBI
T2T-CHM13v2.0481,054,227 - 81,160,154 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001365006   ⟹   NP_001351935
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,713,387 - 77,820,269 (-)NCBI
T2T-CHM13v2.0481,054,227 - 81,161,055 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001365007   ⟹   NP_001351936
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,713,387 - 77,819,023 (-)NCBI
T2T-CHM13v2.0481,054,227 - 81,159,787 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387835   ⟹   NP_001374764
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,713,387 - 77,820,269 (-)NCBI
T2T-CHM13v2.0481,054,227 - 81,161,055 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387836   ⟹   NP_001374765
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,713,387 - 77,820,269 (-)NCBI
T2T-CHM13v2.0481,054,227 - 81,161,055 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387837   ⟹   NP_001374766
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,713,387 - 77,819,023 (-)NCBI
T2T-CHM13v2.0481,054,227 - 81,159,787 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387838   ⟹   NP_001374767
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,713,387 - 77,819,368 (-)NCBI
T2T-CHM13v2.0481,054,227 - 81,160,154 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387839   ⟹   NP_001374768
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,713,387 - 77,820,269 (-)NCBI
T2T-CHM13v2.0481,054,227 - 81,161,055 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387840   ⟹   NP_001374769
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,713,387 - 77,819,023 (-)NCBI
T2T-CHM13v2.0481,054,227 - 81,159,787 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387841   ⟹   NP_001374770
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,713,387 - 77,819,368 (-)NCBI
T2T-CHM13v2.0481,054,227 - 81,160,154 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387842   ⟹   NP_001374771
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,713,387 - 77,819,368 (-)NCBI
T2T-CHM13v2.0481,054,227 - 81,160,154 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001387843   ⟹   NP_001374772
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,713,387 - 77,819,368 (-)NCBI
T2T-CHM13v2.0481,054,227 - 81,160,154 (-)NCBI
Sequence:
RefSeq Acc Id: NM_144571   ⟹   NP_653172
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,713,387 - 77,819,368 (-)NCBI
GRCh37478,634,541 - 78,740,764 (-)NCBI
Build 36478,853,565 - 78,959,568 (-)NCBI Archive
Celera475,935,929 - 76,042,004 (-)RGD
HuRef474,386,458 - 74,492,461 (-)RGD
CHM1_1478,611,478 - 78,717,345 (-)NCBI
T2T-CHM13v2.0481,054,227 - 81,160,154 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011531806   ⟹   XP_011530108
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,713,387 - 77,819,368 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011531807   ⟹   XP_011530109
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,713,387 - 77,819,368 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011531808   ⟹   XP_011530110
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,713,387 - 77,819,368 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011531809   ⟹   XP_011530111
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,713,387 - 77,819,368 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047449962   ⟹   XP_047305918
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,713,387 - 77,801,299 (-)NCBI
RefSeq Acc Id: XM_047449963   ⟹   XP_047305919
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38477,713,387 - 77,819,368 (-)NCBI
RefSeq Acc Id: XM_054349499   ⟹   XP_054205474
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0481,054,227 - 81,160,154 (-)NCBI
RefSeq Acc Id: XM_054349500   ⟹   XP_054205475
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0481,054,227 - 81,160,154 (-)NCBI
RefSeq Acc Id: XM_054349501   ⟹   XP_054205476
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0481,054,227 - 81,160,154 (-)NCBI
RefSeq Acc Id: XM_054349502   ⟹   XP_054205477
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0481,054,227 - 81,160,154 (-)NCBI
RefSeq Acc Id: XM_054349503   ⟹   XP_054205478
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0481,054,227 - 81,142,053 (-)NCBI
RefSeq Acc Id: XM_054349504   ⟹   XP_054205479
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0481,054,227 - 81,160,154 (-)NCBI
RefSeq Acc Id: XM_054349505   ⟹   XP_054205480
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0481,054,227 - 81,159,787 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001273719 (Get FASTA)   NCBI Sequence Viewer  
  NP_001351935 (Get FASTA)   NCBI Sequence Viewer  
  NP_001351936 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374764 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374765 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374766 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374767 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374768 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374769 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374770 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374771 (Get FASTA)   NCBI Sequence Viewer  
  NP_001374772 (Get FASTA)   NCBI Sequence Viewer  
  NP_653172 (Get FASTA)   NCBI Sequence Viewer  
  XP_011530108 (Get FASTA)   NCBI Sequence Viewer  
  XP_011530109 (Get FASTA)   NCBI Sequence Viewer  
  XP_011530110 (Get FASTA)   NCBI Sequence Viewer  
  XP_011530111 (Get FASTA)   NCBI Sequence Viewer  
  XP_047305918 (Get FASTA)   NCBI Sequence Viewer  
  XP_047305919 (Get FASTA)   NCBI Sequence Viewer  
  XP_054205474 (Get FASTA)   NCBI Sequence Viewer  
  XP_054205475 (Get FASTA)   NCBI Sequence Viewer  
  XP_054205476 (Get FASTA)   NCBI Sequence Viewer  
  XP_054205477 (Get FASTA)   NCBI Sequence Viewer  
  XP_054205478 (Get FASTA)   NCBI Sequence Viewer  
  XP_054205479 (Get FASTA)   NCBI Sequence Viewer  
  XP_054205480 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAB71707 (Get FASTA)   NCBI Sequence Viewer  
  BAG64470 (Get FASTA)   NCBI Sequence Viewer  
  BAG65232 (Get FASTA)   NCBI Sequence Viewer  
  CAB61415 (Get FASTA)   NCBI Sequence Viewer  
  EAX05818 (Get FASTA)   NCBI Sequence Viewer  
  EAX05819 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000423750
  ENSP00000423750.2
  ENSP00000424896
  ENSP00000424896.1
  ENSP00000425571
  ENSP00000425571.2
  ENSP00000425836.3
  ENSP00000497467
  ENSP00000497467.1
GenBank Protein Q96LI5 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_653172   ⟸   NM_144571
- Peptide Label: isoform 1
- UniProtKB: Q96LI5 (UniProtKB/Swiss-Prot),   Q9UF92 (UniProtKB/Swiss-Prot),   B4E0K8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001273719   ⟸   NM_001286790
- Peptide Label: isoform 1
- UniProtKB: Q96LI5 (UniProtKB/Swiss-Prot),   Q9UF92 (UniProtKB/Swiss-Prot),   B4E0K8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011530108   ⟸   XM_011531806
- Peptide Label: isoform X1
- UniProtKB: B4E0K8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011530109   ⟸   XM_011531807
- Peptide Label: isoform X2
- UniProtKB: B4E0K8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011530111   ⟸   XM_011531809
- Peptide Label: isoform X4
- UniProtKB: B4E0K8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011530110   ⟸   XM_011531808
- Peptide Label: isoform X3
- UniProtKB: B4E0K8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001351935   ⟸   NM_001365006
- Peptide Label: isoform 2
- UniProtKB: B4E0K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001351936   ⟸   NM_001365007
- Peptide Label: isoform 2
- UniProtKB: B4E0K8 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSP00000497467   ⟸   ENST00000649644
Ensembl Acc Id: ENSP00000424896   ⟸   ENST00000504123
Ensembl Acc Id: ENSP00000425836   ⟸   ENST00000504804
Ensembl Acc Id: ENSP00000425571   ⟸   ENST00000512485
Ensembl Acc Id: ENSP00000423750   ⟸   ENST00000515506
Ensembl Acc Id: ENSP00000426269   ⟸   ENST00000515441
RefSeq Acc Id: NP_001374764   ⟸   NM_001387835
- Peptide Label: isoform 3
- UniProtKB: H0Y9Z5 (UniProtKB/TrEMBL),   B4E0K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001374768   ⟸   NM_001387839
- Peptide Label: isoform 4
- UniProtKB: H0Y9C1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001374765   ⟸   NM_001387836
- Peptide Label: isoform 3
- UniProtKB: H0Y9Z5 (UniProtKB/TrEMBL),   B4E0K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001374771   ⟸   NM_001387842
- Peptide Label: isoform 6
- UniProtKB: B4E0K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001374767   ⟸   NM_001387838
- Peptide Label: isoform 3
- UniProtKB: H0Y9Z5 (UniProtKB/TrEMBL),   B4E0K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001374770   ⟸   NM_001387841
- Peptide Label: isoform 5
- UniProtKB: B4E0K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001374772   ⟸   NM_001387843
- Peptide Label: isoform 6
- UniProtKB: B4E0K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001374769   ⟸   NM_001387840
- Peptide Label: isoform 4
- UniProtKB: H0Y9C1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001374766   ⟸   NM_001387837
- Peptide Label: isoform 3
- UniProtKB: H0Y9Z5 (UniProtKB/TrEMBL),   B4E0K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047305919   ⟸   XM_047449963
- Peptide Label: isoform X6
- UniProtKB: H0Y9Z5 (UniProtKB/TrEMBL),   B4E0K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_047305918   ⟸   XM_047449962
- Peptide Label: isoform X5
- UniProtKB: B4E0K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054205477   ⟸   XM_054349502
- Peptide Label: isoform X4
- UniProtKB: B4E0K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054205475   ⟸   XM_054349500
- Peptide Label: isoform X2
- UniProtKB: B4E0K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054205474   ⟸   XM_054349499
- Peptide Label: isoform X1
- UniProtKB: B4E0K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054205476   ⟸   XM_054349501
- Peptide Label: isoform X3
- UniProtKB: B4E0K8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054205479   ⟸   XM_054349504
- Peptide Label: isoform X6
- UniProtKB: B4E0K8 (UniProtKB/TrEMBL),   H0Y9Z5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054205480   ⟸   XM_054349505
- Peptide Label: isoform X6
- UniProtKB: B4E0K8 (UniProtKB/TrEMBL),   H0Y9Z5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054205478   ⟸   XM_054349503
- Peptide Label: isoform X5
- UniProtKB: B4E0K8 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q96LI5-F1-model_v2 AlphaFold Q96LI5 1-555 view protein structure

Promoters
RGD ID:6802132
Promoter ID:HG_KWN:48559
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000264903
Position:
Human AssemblyChrPosition (strand)Source
Build 36478,959,086 - 78,960,557 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:18042 AgrOrtholog
COSMIC CNOT6L COSMIC
Ensembl Genes ENSG00000138767 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000504123 ENTREZGENE
  ENST00000504123.7 UniProtKB/Swiss-Prot
  ENST00000504804.7 UniProtKB/TrEMBL
  ENST00000512485 ENTREZGENE
  ENST00000512485.6 UniProtKB/TrEMBL
  ENST00000515506 ENTREZGENE
  ENST00000515506.6 UniProtKB/TrEMBL
  ENST00000649644 ENTREZGENE
  ENST00000649644.1 UniProtKB/TrEMBL
Gene3D-CATH 3.60.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000138767 GTEx
HGNC ID HGNC:18042 ENTREZGENE
Human Proteome Map CNOT6L Human Proteome Map
InterPro CCR4/nocturin_mRNA_transcr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Deadenylase_CCR4b UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Endo/exonu/phosph_ase_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Endo/exonuclease/phosphatase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:246175 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 246175 ENTREZGENE
OMIM 618069 OMIM
PANTHER CARBON CATABOLITE REPRESSOR PROTEIN 4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6-LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Exo_endo_phos UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA38480 PharmGKB
PROSITE LRR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART LRR_TYP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56219 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B4E0K8 ENTREZGENE, UniProtKB/TrEMBL
  CNO6L_HUMAN UniProtKB/Swiss-Prot
  D6RIW9_HUMAN UniProtKB/TrEMBL
  H0Y9C1 ENTREZGENE, UniProtKB/TrEMBL
  H0Y9Z5 ENTREZGENE, UniProtKB/TrEMBL
  Q96LI5 ENTREZGENE
  Q9UF92 ENTREZGENE
UniProt Secondary Q9UF92 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-07 CNOT6L  CCR4-NOT transcription complex subunit 6 like    CCR4-NOT transcription complex subunit 6-like  Symbol and/or name change 5135510 APPROVED
2015-12-08 CNOT6L  CCR4-NOT transcription complex subunit 6-like    CCR4-NOT transcription complex, subunit 6-like  Symbol and/or name change 5135510 APPROVED