Erich1 (glutamate-rich 1) - Rat Genome Database

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Gene: Erich1 (glutamate-rich 1) Rattus norvegicus
Analyze
Symbol: Erich1
Name: glutamate-rich 1
RGD ID: 1559872
Description: Orthologous to human ERICH1 (glutamate rich 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; ketamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: glutamate-rich protein 1; hypothetical LOC306622; LOC306622; RGD1559872
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81682,203,536 - 82,271,361 (+)NCBIGRCr8
mRatBN7.21675,501,322 - 75,569,129 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1675,501,384 - 75,569,128 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1680,779,708 - 80,843,573 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01684,233,255 - 84,297,119 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01679,481,457 - 79,547,675 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01680,601,873 - 80,667,774 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1680,601,973 - 80,667,781 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01680,168,188 - 80,234,843 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41680,333,204 - 80,404,945 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1673,314,066 - 73,379,917 (+)NCBICelera
Cytogenetic Map16q12.5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Erich1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81682,203,536 - 82,271,361 (+)NCBIGRCr8
mRatBN7.21675,501,322 - 75,569,129 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1675,501,384 - 75,569,128 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1680,779,708 - 80,843,573 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01684,233,255 - 84,297,119 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01679,481,457 - 79,547,675 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01680,601,873 - 80,667,774 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1680,601,973 - 80,667,781 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01680,168,188 - 80,234,843 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41680,333,204 - 80,404,945 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1673,314,066 - 73,379,917 (+)NCBICelera
Cytogenetic Map16q12.5NCBI
ERICH1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388614,746 - 731,224 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8614,746 - 738,106 (-)EnsemblGRCh38hg38GRCh38
GRCh378564,746 - 681,224 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368604,200 - 671,226 (-)NCBINCBI36Build 36hg18NCBI36
Celera8579,581 - 644,934 (-)NCBICelera
Cytogenetic Map8p23.3NCBI
HuRef8454,925 - 520,561 (-)NCBIHuRef
CHM1_18608,649 - 673,552 (-)NCBICHM1_1
T2T-CHM13v2.08412,067 - 522,796 (-)NCBIT2T-CHM13v2.0
Erich1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39814,075,051 - 14,140,393 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl814,077,561 - 14,140,301 (-)EnsemblGRCm39 Ensembl
GRCm38814,025,882 - 14,090,338 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl814,027,561 - 14,090,301 (-)EnsemblGRCm38mm10GRCm38
MGSCv37814,027,565 - 14,090,327 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36814,027,542 - 14,090,278 (-)NCBIMGSCv36mm8
Celera814,187,423 - 14,250,203 (-)NCBICelera
Cytogenetic Map8A1.1NCBI
cM Map86.47NCBI
Erich1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540358,508,113 - 58,580,682 (+)NCBIChiLan1.0ChiLan1.0
ERICH1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2715,332,284 - 15,414,116 (-)NCBINHGRI_mPanPan1-v2
Mhudiblu_PPA_v086,667,945 - 6,737,597 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18575,605 - 642,410 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8582,563 - 630,015 (-)Ensemblpanpan1.1panPan2
ERICH1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13730,104,227 - 30,139,217 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3730,104,227 - 30,120,994 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3730,866,469 - 30,910,346 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03730,129,468 - 30,173,976 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.13730,035,008 - 30,077,467 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03729,971,597 - 30,015,968 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03729,987,196 - 30,029,747 (-)NCBIUU_Cfam_GSD_1.0
Erich1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404943239,356 - 300,789 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936615239,256 - 300,789 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ERICH1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1532,540,893 - 32,592,779 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11532,536,685 - 32,592,815 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ERICH1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18444,997 - 504,020 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8445,395 - 503,934 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605442,084,901 - 42,143,838 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Erich1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624861320,818 - 410,341 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Erich1
567 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:11
Count of miRNA genes:11
Interacting mature miRNAs:11
Transcripts:ENSRNOT00000064468
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2300163Bmd64Bone mineral density QTL 645.30.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)163775215682752156Rat
7411648Foco22Food consumption QTL 22150.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)165272646484729064Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
1578768Stresp22Stress response QTL 222.8thymus mass (VT:0004954)thymus wet weight (CMO:0000855)163528887080288870Rat
2293690Bss45Bone structure and strength QTL 455.130.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)163775215682752156Rat
8694364Abfw7Abdominal fat weight QTL 712.220.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)165272646484729064Rat
8694429Bw164Body weight QTL 16450.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)165272646484729064Rat
7205510Activ5Activity QTL 53.780.00028locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)164239634584729064Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
631525Pia14Pristane induced arthritis QTL 144.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)165571108783402471Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000064468   ⟹   ENSRNOP00000061175
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1675,501,384 - 75,569,128 (+)Ensembl
Rnor_6.0 Ensembl1680,601,973 - 80,667,781 (+)Ensembl
RefSeq Acc Id: NM_001127680   ⟹   NP_001121152
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81682,203,606 - 82,271,060 (+)NCBI
mRatBN7.21675,501,370 - 75,568,827 (+)NCBI
Rnor_6.01680,601,961 - 80,667,472 (+)NCBI
Rnor_5.01680,168,188 - 80,234,843 (+)NCBI
RGSC_v3.41680,333,204 - 80,404,945 (+)RGD
Celera1673,314,066 - 73,379,917 (+)RGD
Sequence:
RefSeq Acc Id: XM_006253395   ⟹   XP_006253457
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81682,203,536 - 82,271,361 (+)NCBI
mRatBN7.21675,501,322 - 75,569,129 (+)NCBI
Rnor_6.01680,601,873 - 80,667,774 (+)NCBI
Rnor_5.01680,168,188 - 80,234,843 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039094597   ⟹   XP_038950525
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81682,203,536 - 82,268,262 (+)NCBI
mRatBN7.21675,501,322 - 75,564,953 (+)NCBI
RefSeq Acc Id: XM_039094598   ⟹   XP_038950526
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81682,203,536 - 82,271,361 (+)NCBI
mRatBN7.21675,501,322 - 75,569,129 (+)NCBI
RefSeq Acc Id: XM_039094599   ⟹   XP_038950527
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81682,206,172 - 82,271,361 (+)NCBI
mRatBN7.21675,503,927 - 75,569,129 (+)NCBI
RefSeq Acc Id: XM_039094600   ⟹   XP_038950528
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81682,217,734 - 82,271,361 (+)NCBI
mRatBN7.21675,515,497 - 75,569,129 (+)NCBI
RefSeq Acc Id: NP_001121152   ⟸   NM_001127680
- UniProtKB: A6IWE5 (UniProtKB/TrEMBL),   F7FM87 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006253457   ⟸   XM_006253395
- Peptide Label: isoform X1
- UniProtKB: F7FM87 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000061175   ⟸   ENSRNOT00000064468
RefSeq Acc Id: XP_038950526   ⟸   XM_039094598
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038950525   ⟸   XM_039094597
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038950527   ⟸   XM_039094599
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038950528   ⟸   XM_039094600
- Peptide Label: isoform X4

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F7FM87-F1-model_v2 AlphaFold F7FM87 1-332 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700219
Promoter ID:EPDNEW_R10743
Type:initiation region
Name:Erich1_1
Description:glutamate-rich 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01680,601,970 - 80,602,030EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1559872 AgrOrtholog
BioCyc Gene G2FUF-10743 BioCyc
Ensembl Genes ENSRNOG00000042114 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064468.4 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:9091442 IMAGE-MGC_LOAD
InterPro ERICH1 UniProtKB/TrEMBL
KEGG Report rno:306622 UniProtKB/TrEMBL
MGC_CLONE MGC:189402 IMAGE-MGC_LOAD
NCBI Gene 306622 ENTREZGENE
PANTHER GLUTAMATE-RICH PROTEIN 1 UniProtKB/TrEMBL
  PTHR22444 UniProtKB/TrEMBL
PhenoGen Erich1 PhenoGen
RatGTEx ENSRNOG00000042114 RatGTEx
UniProt A6IWE5 ENTREZGENE, UniProtKB/TrEMBL
  F7FM87 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-28 Erich1  glutamate-rich 1  RGD1559872_predicted  RGD1559872 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1559872_predicted  RGD1559872 (predicted)  LOC306622  hypothetical LOC306622  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC306622  hypothetical LOC306622      Symbol and Name status set to provisional 70820 PROVISIONAL