Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: ARC (activity regulated cytoskeleton associated protein) Homo sapiens
Symbol: ARC
Name: activity regulated cytoskeleton associated protein
RGD ID: 730952
Description: Predicted to have mRNA binding activity. Involved in cell migration; cytoskeleton organization; and regulation of cell morphogenesis. Localizes to cytoplasm and plasma membrane; INTERACTS WITH (S)-nicotine; 15-acetyldeoxynivalenol; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: activity-regulated gene 3.1 protein homolog; ARC/ARG3.1; Arg3.1; hArc; KIAA0278
Mus musculus (house mouse) : Arc (activity regulated cytoskeletal-associated protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Arc (activity-regulated cytoskeleton-associated protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arc (activity regulated cytoskeleton associated protein)
Pan paniscus (bonobo/pygmy chimpanzee) : ARC (activity regulated cytoskeleton associated protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arc (activity regulated cytoskeleton associated protein)
Sus scrofa (pig) : ARC (activity regulated cytoskeleton associated protein)
Chlorocebus sabaeus (African green monkey) : ARC (activity regulated cytoskeleton associated protein)
Heterocephalus glaber (naked mole-rat) : Arc (activity regulated cytoskeleton associated protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl8142,611,049 - 142,614,479 (-)EnsemblGRCh38hg38GRCh38
GRCh388142,611,049 - 142,614,479 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378143,692,405 - 143,695,833 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368143,689,412 - 143,692,835 (-)NCBINCBI36hg18NCBI36
Build 348143,689,411 - 143,692,835NCBI
Celera8140,003,980 - 140,007,899 (-)NCBI
Cytogenetic Map8q24.3NCBI
HuRef8138,948,085 - 138,951,389 (-)NCBIHuRef
CHM1_18143,732,641 - 143,736,069 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ARC
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730952
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.