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ONTOLOGY REPORT - ANNOTATIONS

Term:diencephalon development
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Accession:GO:0021536 term browser browse the term
Definition:The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.


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diencephalon development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sema5a semaphorin 5A involved_in IMP PMID:15603739 UniProt PMID:15603739 RGD:8553809 NCBI chr 2:85,020,724...85,451,938
Ensembl chr 2:83,309,843...83,741,084 		JBrowse link
G Six3 SIX homeobox 3 acts_upstream_of_or_within ISO MGI:98953 (PMID:18094027) RGD PMID:18094027 NCBI chr 6:14,791,937...14,796,365
Ensembl chr 6:9,036,434...9,053,301 		JBrowse link
G Wnt1 Wnt family member 1 acts_upstream_of_or_within ISO
IEA		 MGI:102764 (PMID:18094027)
GO_REF:0000107		 RGD
Ensembl		 PMID:18094027 GO_REF:0000107 NCBI chr 7:131,817,558...131,821,605
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
adenohypophysis development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 acts_upstream_of_or_within ISO
IEA		 MGI:3576789 (PMID:9140068)
GO_REF:0000107		 RGD
Ensembl		 PMID:9140068 GO_REF:0000107 NCBI chr 8:58,605,403...58,669,339
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Ghrh growth hormone releasing hormone acts_upstream_of_or_within TAS
ISO		 MGI:3051561 (PMID:15985453) RGD PMID:15985453 PMID:12511850 RGD:1601329 NCBI chr 3:166,412,763...166,432,519
Ensembl chr 3:145,992,763...146,011,889 		JBrowse link
G Ghrhr growth hormone releasing hormone receptor acts_upstream_of_or_within ISO
IEA		 MGI:1856425 (PMID:1270792), (PMID:1329576), (PMID:1504465)
GO_REF:0000107		 RGD
Ensembl		 PMID:1270792 PMID:1329576 PMID:1504465 GO_REF:0000107 NCBI chr 4:85,830,345...85,863,127
Ensembl chr 4:84,500,212...84,532,776 		JBrowse link
G Gsx1 GS homeobox 1 acts_upstream_of_or_within ISO
IEA		 MGI:2154448 (PMID:8631293)
GO_REF:0000107		 RGD
Ensembl		 PMID:8631293 GO_REF:0000107 NCBI chr12:7,880,663...7,882,947
Ensembl chr12:7,881,460...7,882,753 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 acts_upstream_of_or_within ISO
IEA		 MGI:3808031 (PMID:18996108)
GO_REF:0000107		 RGD
Ensembl		 PMID:18996108 GO_REF:0000107 NCBI chr11:84,210,632...84,213,045
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 IMP RGD PMID:16216912 RGD:1601440 NCBI chr11:16,763,312...16,781,295
Ensembl chr11:3,317,058...3,334,801 		JBrowse link
G Prop1 PROP paired-like homeobox 1 acts_upstream_of_or_within ISO
IEA		 (PMID:18996108)
GO_REF:0000107		 RGD
Ensembl		 PMID:18996108 GO_REF:0000107 NCBI chr10:35,772,968...35,775,443
Ensembl chr10:35,271,973...35,274,434 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO
IEA		 MGI:2386303 (PMID:9247269)
GO_REF:0000107		 RGD
Ensembl		 PMID:9247269 GO_REF:0000107 NCBI chr 1:31,537,990...31,578,962
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Sox2 SRY-box transcription factor 2 acts_upstream_of_or_within IEP
ISO		 MGI:2449045 (PMID:16932809) RGD PMID:16932809 PMID:21815952 RGD:8661681 NCBI chr 2:119,465,131...119,467,542
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
adenohypophysis morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Duox2 dual oxidase 2 acts_upstream_of_or_within ISO
IEA		 MGI:3712359 (PMID:17440044)
GO_REF:0000107		 RGD
Ensembl		 PMID:17440044 GO_REF:0000107 NCBI chr 3:129,680,543...129,698,886
Ensembl chr 3:109,226,924...109,245,902 		JBrowse link
cell migration in diencephalon term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxb1 forkhead box B1 involved_in ISO (PMID:19046377) RGD PMID:19046377 NCBI chr 8:70,407,221...70,409,841
Ensembl chr 8:70,408,186...70,409,781 		JBrowse link
corticotropin hormone secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 acts_upstream_of_or_within ISO
IEA		 (PMID:9463347)
GO_REF:0000107		 RGD
Ensembl		 PMID:9463347 GO_REF:0000107 NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Fgf2 fibroblast growth factor 2 acts_upstream_of_or_within ISO
IEA		 (PMID:9463347)
GO_REF:0000107		 RGD
Ensembl		 PMID:9463347 GO_REF:0000107 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO
IEA		 (PMID:9463347)
GO_REF:0000107		 RGD
Ensembl		 PMID:9463347 GO_REF:0000107 NCBI chr 1:254,533,504...254,539,605
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
diencephalon morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Otx1 orthodenticle homeobox 1 acts_upstream_of_or_within ISO
IEA		 MGI:97451 (PMID:20816794)
GO_REF:0000107		 RGD
Ensembl		 PMID:20816794 GO_REF:0000107 NCBI chr14:100,283,406...100,290,421
Ensembl chr14:96,082,151...96,089,086 		JBrowse link
G Otx2 orthodenticle homeobox 2 acts_upstream_of_or_within ISO MGI:97450 (PMID:20816794) RGD PMID:20816794 NCBI chr15:24,422,876...24,432,709
Ensembl chr15:21,943,191...21,953,416 		JBrowse link
G Sox2 SRY-box transcription factor 2 acts_upstream_of_or_within ISO MGI:2181440|MGI:3052123 (PMID:15240551) RGD PMID:15240551 NCBI chr 2:119,465,131...119,467,542
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
globus pallidus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arx aristaless related homeobox acts_upstream_of_or_within ISO
IEA		 MGI:2679972 (PMID:17460091)
GO_REF:0000107		 RGD
Ensembl		 PMID:17460091 GO_REF:0000107 NCBI chr  X:62,010,097...62,022,009
Ensembl chr  X:58,016,233...58,028,142 		JBrowse link
G Kcnc1 potassium voltage-gated channel subfamily C member 1 IEP RGD PMID:10482766 RGD:9685780 NCBI chr 1:106,039,247...106,081,034
Ensembl chr 1:96,902,953...96,944,744 		JBrowse link
G Kcnc2 potassium voltage-gated channel subfamily C member 2 IEP RGD PMID:10482766 RGD:9685780 NCBI chr 7:49,586,274...49,770,212
Ensembl chr 7:47,700,288...47,883,968 		JBrowse link
G Nkx2-1 NK2 homeobox 1 involved_in
acts_upstream_of_or_within		 ISO
IEA		 (PMID:11854319)
GO_REF:0000107
MGI:3653645 (PMID:20181579)		 RGD
Ensembl		 PMID:11854319 PMID:20181579 GO_REF:0000107 NCBI chr 6:79,731,677...79,735,952
Ensembl chr 6:73,996,601...73,999,791 		JBrowse link
gonadotrophin-releasing hormone neuronal migration to the hypothalamus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ndnf neuron-derived neurotrophic factor involved_in ISO (PMID:31883645) RGD PMID:31883645 NCBI chr 4:96,274,147...96,311,624
Ensembl chr 4:94,944,360...94,981,873 		JBrowse link
G Nrp1 neuropilin 1 involved_in ISO
IEA		 (PMID:21059704)
GO_REF:0000107		 RGD
Ensembl		 PMID:21059704 GO_REF:0000107 NCBI chr19:73,256,557...73,411,705
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Nrp2 neuropilin 2 involved_in IEA
ISO		 GO_REF:0000107
(PMID:21059704)		 Ensembl
RGD		 PMID:21059704 GO_REF:0000107 NCBI chr 9:71,616,602...71,731,869
Ensembl chr 9:64,123,132...64,237,958 		JBrowse link
G Plxna1 plexin A1 involved_in ISO
IEA		 UniProtKB:P70208 (PMID:31690636)
GO_REF:0000107		 RGD
Ensembl		 PMID:31690636 GO_REF:0000107 NCBI chr 4:123,295,165...123,340,132
Ensembl chr 4:121,737,945...122,024,196 		JBrowse link
G Plxna3 plexin A3 involved_in ISO
IEA		 UniProtKB:P70206 (PMID:31690636)
GO_REF:0000107		 RGD
Ensembl		 PMID:31690636 GO_REF:0000107 NCBI chr  X:157,266,986...157,282,896
Ensembl chr  X:152,115,819...152,131,603 		JBrowse link
G Sema3a semaphorin 3A involved_in ISO (PMID:21059704) RGD PMID:21059704 NCBI chr 4:22,239,418...22,709,907
Ensembl chr 4:21,287,982...21,494,432 		JBrowse link
G Sema3e semaphorin 3E involved_in ISO
IEA		 (PMID:25985275)
GO_REF:0000107		 RGD
Ensembl		 PMID:25985275 GO_REF:0000107 NCBI chr 4:21,252,686...21,510,449
Ensembl chr 4:20,299,718...20,555,229 		JBrowse link
habenula development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 acts_upstream_of_or_within ISO (PMID:19906978) RGD PMID:19906978 NCBI chr 3:62,098,739...62,115,926
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Pax6 paired box 6 acts_upstream_of_or_within ISO
IEA		 MGI:1856155 (PMID:24528677)
GO_REF:0000107		 RGD
Ensembl		 PMID:24528677 GO_REF:0000107 NCBI chr 3:112,590,034...112,611,771
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Pou4f1 POU class 4 homeobox 1 acts_upstream_of_or_within ISO MGI:2387665|MGI:3512089 (PMID:19906978) RGD PMID:19906978 NCBI chr15:87,668,328...87,674,643
Ensembl chr15:81,257,781...81,259,728 		JBrowse link
hypophysis morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prop1 PROP paired-like homeobox 1 acts_upstream_of_or_within ISO
IEA		 MGI:3690463 (PMID:16678101)
GO_REF:0000107		 RGD
Ensembl		 PMID:16678101 GO_REF:0000107 NCBI chr10:35,772,968...35,775,443
Ensembl chr10:35,271,973...35,274,434 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO
IEA		 MGI:1857617 (PMID:15037319)
GO_REF:0000107		 RGD
Ensembl		 PMID:15037319 GO_REF:0000107 NCBI chr16:3,702,300...3,724,860
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
hypothalamus cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hap1 huntingtin-associated protein 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:24355921)		 Ensembl
RGD		 PMID:24355921 GO_REF:0000107 NCBI chr10:85,778,267...85,786,553
Ensembl chr10:85,277,890...85,286,126 		JBrowse link
G Otp orthopedia homeobox acts_upstream_of_or_within ISO
IEA		 MGI:2180541 (PMID:10557207)
GO_REF:0000107		 RGD
Ensembl		 PMID:10557207 GO_REF:0000107 NCBI chr 2:26,108,158...26,116,359
Ensembl chr 2:26,108,163...26,116,359 		JBrowse link
G Pou3f2 POU class 3 homeobox 2 acts_upstream_of_or_within ISO
IEA		 MGI:1857996 (PMID:8543156)
GO_REF:0000107		 RGD
Ensembl		 PMID:8543156 GO_REF:0000107 NCBI chr 5:36,077,930...36,083,838
Ensembl chr 5:36,077,930...36,083,838 		JBrowse link
G Prdm13 PR/SET domain 13 involved_in ISO (PMID:34730112) RGD PMID:34730112 NCBI chr 5:35,220,815...35,232,866
Ensembl chr 5:35,225,435...35,232,881 		JBrowse link
G Prop1 PROP paired-like homeobox 1 acts_upstream_of_or_within ISO
IEA		 MGI:1856842 (PMID:9067988)
GO_REF:0000107		 RGD
Ensembl		 PMID:9067988 GO_REF:0000107 NCBI chr10:35,772,968...35,775,443
Ensembl chr10:35,271,973...35,274,434 		JBrowse link
hypothalamus cell migration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxb1 forkhead box B1 involved_in ISO (PMID:19046377) RGD PMID:19046377 NCBI chr 8:70,407,221...70,409,841
Ensembl chr 8:70,408,186...70,409,781 		JBrowse link
G Pitx2 paired-like homeodomain 2 acts_upstream_of_or_within ISO MGI:1857846 (PMID:18206388) RGD PMID:18206388 NCBI chr 2:217,717,738...217,737,293
Ensembl chr 2:217,717,693...217,737,293 		JBrowse link
hypothalamus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO
IEA		 MGI:1857429 (PMID:15342910)
GO_REF:0000107		 RGD
Ensembl		 PMID:15342910 GO_REF:0000107 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bloc1s6 biogenesis of lysosomal organelles complex 1 subunit 6 acts_upstream_of_or_within ISO
IEA		 MGI:1856982 (PMID:30498428)
GO_REF:0000107		 RGD
Ensembl		 PMID:30498428 GO_REF:0000107 NCBI chr 3:130,269,979...130,280,109
Ensembl chr 3:109,816,366...109,828,308 		JBrowse link
G Crh corticotropin releasing hormone IEP RGD PMID:20002962 RGD:5130950 NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IEP RGD PMID:20002962 RGD:5130950 NCBI chr10:89,540,192...89,583,466
Ensembl chr10:89,040,203...89,083,481 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IEP RGD PMID:20002962 RGD:5130950 NCBI chr 4:85,553,163...85,596,203
Ensembl chr 4:84,224,002...84,265,904 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in IEA
ISO		 GO_REF:0000107
MGI:1858008 (PMID:32868762)		 Ensembl
RGD		 PMID:32868762 GO_REF:0000107 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IEP RGD PMID:15804399 RGD:4891928 NCBI chr 8:63,449,148...63,476,534
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Esr2 estrogen receptor 2 IEP RGD PMID:12960049 RGD:1582276 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor IEP RGD PMID:8946059 RGD:2313681 NCBI chr 8:39,303,936...39,426,022
Ensembl chr 8:31,045,945...31,168,010 		JBrowse link
G Gsx1 GS homeobox 1 acts_upstream_of_or_within ISO
IEA		 MGI:2154448 (PMID:8631293)
GO_REF:0000107		 RGD
Ensembl		 PMID:8631293 GO_REF:0000107 NCBI chr12:7,880,663...7,882,947
Ensembl chr12:7,881,460...7,882,753 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IEP RGD PMID:23291449 RGD:7207858 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Ncoa1 nuclear receptor coactivator 1 IEP RGD PMID:12551846 RGD:5688241 NCBI chr 6:32,952,090...33,229,829
Ensembl chr 6:27,232,611...27,475,664 		JBrowse link
G Nkx2-1 NK2 homeobox 1 involved_in IEA
ISO		 GO_REF:0000107
MGI:5302534 (PMID:32868762)		 Ensembl
RGD		 PMID:32868762 GO_REF:0000107 NCBI chr 6:79,731,677...79,735,952
Ensembl chr 6:73,996,601...73,999,791 		JBrowse link
G Nkx2-6 NK2 homeobox 6 involved_in ISO (PMID:9621431) RGD PMID:9621431 NCBI chr15:44,443,151...44,447,248
Ensembl chr15:44,443,101...44,447,247 		JBrowse link
G Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1 involved_in ISO
IEA		 (PMID:20512159)
GO_REF:0000107		 RGD
Ensembl		 PMID:20512159 GO_REF:0000107 NCBI chr13:41,908,179...41,981,611
Ensembl chr13:39,352,247...39,429,169 		JBrowse link
G Rax retina and anterior neural fold homeobox acts_upstream_of_or_within ISO
IEA		 MGI:1856862 (PMID:925203)
GO_REF:0000107		 RGD
Ensembl		 PMID:925203 GO_REF:0000107 NCBI chr18:59,463,347...59,467,469
Ensembl chr18:59,463,737...59,467,431 		JBrowse link
G Reln reelin IEP RGD PMID:10436054 RGD:634730 NCBI chr 4:13,628,440...14,055,201
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Sox3 SRY-box transcription factor 3 involved_in ISO (PMID:14981518) RGD PMID:14981518 NCBI chr  X:144,344,892...144,346,971
Ensembl chr  X:139,309,329...139,310,678 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IEP RGD PMID:15804399 PMID:8770891 RGD:4891928, RGD:4892048 NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 IEP RGD PMID:15804399 RGD:4891928 NCBI chr 6:27,178,089...27,217,588
Ensembl chr 6:21,426,215...21,462,112 		JBrowse link
G Uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII involved_in ISO
IEA		 (PMID:16901643)
GO_REF:0000107		 RGD
Ensembl		 PMID:16901643 GO_REF:0000107 NCBI chr10:38,086,691...38,093,871
Ensembl chr10:37,586,888...37,589,169 		JBrowse link
hypothalamus gonadotrophin-releasing hormone neuron development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nhlh2 nescient helix loop helix 2 acts_upstream_of_or_within_positive_effect ISO
IEA		 (PMID:23785158)
GO_REF:0000107		 RGD
Ensembl		 PMID:23785158 GO_REF:0000107 NCBI chr 2:192,132,848...192,138,186
Ensembl chr 2:189,442,711...189,449,625 		JBrowse link
G Ubb ubiquitin B acts_upstream_of_or_within ISO
IEA		 MGI:3774112 (PMID:18299572)
GO_REF:0000107		 RGD
Ensembl		 PMID:18299572 GO_REF:0000107 NCBI chr10:47,746,923...47,748,628
Ensembl chr10:47,245,637...47,249,333 		JBrowse link
lateral geniculate nucleus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit acts_upstream_of_or_within ISO MGI:2158714 (PMID:12097474) RGD PMID:12097474 NCBI chr 2:177,479,091...177,487,306
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
mammillary axonal complex development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Zeb2 zinc finger E-box binding homeobox 2 acts_upstream_of_or_within ISO
IEA		 MGI:2387499|MGI:2668659 (PMID:25741725)
GO_REF:0000107		 RGD
Ensembl		 PMID:25741725 GO_REF:0000107 NCBI chr 3:49,624,028...49,754,323
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
mammillary body development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxb1 forkhead box B1 involved_in ISO (PMID:11170346), (PMID:15654859) RGD PMID:11170346 PMID:15654859 NCBI chr 8:70,407,221...70,409,841
Ensembl chr 8:70,408,186...70,409,781 		JBrowse link
mammillothalamic axonal tract development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxb1 forkhead box B1 involved_in ISO (PMID:10662642), (PMID:11170346) RGD PMID:10662642 PMID:11170346 NCBI chr 8:70,407,221...70,409,841
Ensembl chr 8:70,408,186...70,409,781 		JBrowse link
neurohypophysis development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Otp orthopedia homeobox acts_upstream_of_or_within ISO
IEA		 MGI:2180541 (PMID:10557207)
GO_REF:0000107		 RGD
Ensembl		 PMID:10557207 GO_REF:0000107 NCBI chr 2:26,108,158...26,116,359
Ensembl chr 2:26,108,163...26,116,359 		JBrowse link
G Pou3f2 POU class 3 homeobox 2 acts_upstream_of_or_within ISO
IEA		 MGI:1857996 (PMID:8543156)
GO_REF:0000107		 RGD
Ensembl		 PMID:8543156 GO_REF:0000107 NCBI chr 5:36,077,930...36,083,838
Ensembl chr 5:36,077,930...36,083,838 		JBrowse link
pituitary gland development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1 adenylate cyclase activating polypeptide 1 IEP RGD PMID:18160680 RGD:2325274 NCBI chr 9:120,550,236...120,569,096
Ensembl chr 9:113,103,718...113,109,773 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 IEP RGD PMID:17180597 RGD:2306413 NCBI chr 8:80,758,641...80,837,891
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 IEP RGD PMID:17180597 RGD:2306413 NCBI chr 1:129,392,516...129,436,552
Ensembl chr 1:119,982,277...120,017,436 		JBrowse link
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within ISO
IEA		 MGI:1857137 (PMID:9806931)
GO_REF:0000107		 RGD
Ensembl		 PMID:9806931 GO_REF:0000107 NCBI chr15:22,098,191...22,113,145
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A acts_upstream_of_or_within ISO
IEA		 MGI:2158342|MGI:2158390 (PMID:17359964)
GO_REF:0000107		 RGD
Ensembl		 PMID:17359964 GO_REF:0000107 NCBI chr16:9,740,751...9,786,861
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Cdh1 cadherin 1 IEP RGD PMID:17373711 RGD:2289637 NCBI chr19:51,402,178...51,471,572
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 acts_upstream_of_or_within ISO
IEA		 MGI:2176173|MGI:2181395 (PMID:16141355)
GO_REF:0000107		 RGD
Ensembl		 PMID:16141355 GO_REF:0000107 NCBI chr 9:73,397,333...73,466,339
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor IEP RGD PMID:8946059 RGD:2313681 NCBI chr 8:39,303,936...39,426,022
Ensembl chr 8:31,045,945...31,168,010 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO
IEA		 MGI:1859647 (PMID:11062007)
GO_REF:0000107		 RGD
Ensembl		 PMID:11062007 GO_REF:0000107 NCBI chr 2:52,533,939...52,610,980
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Gata2 GATA binding protein 2 acts_upstream_of_or_within ISO
IEA		 MGI:2179995|MGI:3628639 (PMID:16543408)
GO_REF:0000107		 RGD
Ensembl		 PMID:16543408 GO_REF:0000107 NCBI chr 4:122,211,501...122,225,058
Ensembl chr 4:120,658,986...120,667,761 		JBrowse link
G Gli1 GLI family zinc finger 1 acts_upstream_of_or_within ISO
IEA		 MGI:95728 (PMID:10725236)
GO_REF:0000107		 RGD
Ensembl		 PMID:10725236 GO_REF:0000107 NCBI chr 7:65,042,237...65,054,888
Ensembl chr 7:63,156,926...63,169,251 		JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:95727 (PMID:10725236) RGD PMID:10725236 NCBI chr13:32,499,678...32,716,418
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 acts_upstream_of_or_within ISO
IEA		 MGI:104876|MGI:2149672 (PMID:17015435), (PMID:17426285)
GO_REF:0000107		 RGD
Ensembl		 PMID:17015435 PMID:17426285 GO_REF:0000107 NCBI chr11:84,210,632...84,213,045
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hesx1 HESX homeobox 1 involved_in
acts_upstream_of_or_within		 ISO
IEA
IBA		 (PMID:26781211)
GO_REF:0000107
MGI:102764|MGI:1931124|MGI:3822474|MGI:3822475 (PMID:11731482), (PMID:18775421), (PMID:19093031), (PMID:20181723), (PMID:9620767)
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:9620767 PMID:11731482 PMID:18775421 PMID:19093031 PMID:20181723 More... GO_REF:0000033 GO_REF:0000107 NCBI chr16:2,198,589...2,200,694
Ensembl chr16:2,191,852...2,193,957 		JBrowse link
G Hmga2 high mobility group AT-hook 2 acts_upstream_of_or_within ISO
IEA		 MGI:1856426 (PMID:504232)
GO_REF:0000107		 RGD
Ensembl		 PMID:504232 GO_REF:0000107 NCBI chr 7:57,762,710...57,884,555
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Inhbb inhibin subunit beta B IEP RGD PMID:18160680 RGD:2325274 NCBI chr13:33,083,671...33,089,373
Ensembl chr13:30,530,860...30,537,832 		JBrowse link
G Isl1 ISL LIM homeobox 1 acts_upstream_of_or_within ISO
IEA		 MGI:2182246 (PMID:9806931)
GO_REF:0000107		 RGD
Ensembl		 PMID:9806931 GO_REF:0000107 NCBI chr 2:49,813,618...49,823,442
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Kdm1a lysine demethylase 1A acts_upstream_of_or_within ISO MGI:3711561 (PMID:17392792) RGD PMID:17392792 NCBI chr 5:154,066,436...154,121,913
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO
IEA		 MGI:2385819 (PMID:18037398)
GO_REF:0000107		 RGD
Ensembl		 PMID:18037398 GO_REF:0000107 NCBI chr 3:29,424,620...29,432,637
Ensembl chr 3:9,027,425...9,034,480 		JBrowse link
G Msx1 msh homeobox 1 IEP RGD PMID:16451220 RGD:5132608 NCBI chr14:77,185,802...77,189,735
Ensembl chr14:72,961,148...72,964,966 		JBrowse link
G Nkx2-1 NK2 homeobox 1 acts_upstream_of_or_within ISO
IEA		 MGI:1857494 (PMID:9806931)
GO_REF:0000107		 RGD
Ensembl		 PMID:9806931 GO_REF:0000107 NCBI chr 6:79,731,677...79,735,952
Ensembl chr 6:73,996,601...73,999,791 		JBrowse link
G Nog noggin acts_upstream_of_or_within ISO
IEA		 MGI:1862000 (PMID:17359964)
GO_REF:0000107		 RGD
Ensembl		 PMID:17359964 GO_REF:0000107 NCBI chr10:74,625,874...74,627,501
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Pax6 paired box 6 acts_upstream_of_or_within ISO
IEA		 MGI:1856155|MGI:1934347 (PMID:10588713)
GO_REF:0000107		 RGD
Ensembl		 PMID:10588713 GO_REF:0000107 NCBI chr 3:112,590,034...112,611,771
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 IEP RGD PMID:15208361 RGD:2308902 NCBI chr 2:6,130,045...6,176,974
Ensembl chr 2:4,395,543...4,442,434 		JBrowse link
G Pitx1 paired-like homeodomain 1 acts_upstream_of_or_within ISO
IEA		 MGI:1934200 (PMID:10049363)
GO_REF:0000107		 RGD
Ensembl		 PMID:10049363 GO_REF:0000107 NCBI chr17:8,794,134...8,800,292
Ensembl chr17:8,794,134...8,800,291 		JBrowse link
G Pitx2 paired-like homeodomain 2 acts_upstream_of_or_within ISO MGI:1857844|MGI:1857846|MGI:2384494 (PMID:10498698), (PMID:10499586) RGD PMID:10498698 PMID:10499586 NCBI chr 2:217,717,738...217,737,293
Ensembl chr 2:217,717,693...217,737,293 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO MGI:1856024 (PMID:16556738) RGD PMID:16556738 NCBI chr11:16,763,312...16,781,295
Ensembl chr11:3,317,058...3,334,801 		JBrowse link
G Prop1 PROP paired-like homeobox 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1856842 (PMID:11731482)
GO_REF:0000002
GO_REF:0000107		 RGD
InterPro
Ensembl		 PMID:11731482 GO_REF:0000002 GO_REF:0000107 NCBI chr10:35,772,968...35,775,443
Ensembl chr10:35,271,973...35,274,434 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO MGI:3583755 (PMID:17015435) RGD PMID:17015435 NCBI chr14:61,551,366...61,736,220
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
G Sall1 spalt-like transcription factor 1 involved_in ISO
IEA		 (PMID:12065233)
GO_REF:0000107		 RGD
Ensembl		 PMID:12065233 GO_REF:0000107 NCBI chr19:34,179,316...34,196,278
Ensembl chr19:18,007,503...18,022,705 		JBrowse link
G Six3 SIX homeobox 3 acts_upstream_of_or_within
involved_in		 ISO MGI:96071 (PMID:18775421) RGD PMID:18775421 NCBI chr 6:14,791,937...14,796,365
Ensembl chr 6:9,036,434...9,053,301 		JBrowse link
G Sox2 SRY-box transcription factor 2 involved_in ISO
IEA		 (PMID:18285410)
GO_REF:0000107		 RGD
Ensembl		 PMID:18285410 GO_REF:0000107 NCBI chr 2:119,465,131...119,467,542
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Sox3 SRY-box transcription factor 3 involved_in ISO (PMID:14981518) RGD PMID:14981518 NCBI chr  X:144,344,892...144,346,971
Ensembl chr  X:139,309,329...139,310,678 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IEP RGD PMID:8770891 RGD:4892048 NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Tbx19 T-box transcription factor 19 acts_upstream_of_or_within ISO
IEA		 (PMID:11447259)
GO_REF:0000107		 RGD
Ensembl		 PMID:11447259 GO_REF:0000107 NCBI chr13:77,450,848...77,484,475
Ensembl chr13:77,450,849...77,504,163 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO MGI:1926344 (PMID:17919533) RGD PMID:17919533 NCBI chr 1:264,791,335...264,984,225
Ensembl chr 1:254,786,091...254,978,967 		JBrowse link
prolactin secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO
IEA		 MGI:2385819 (PMID:8638120)
GO_REF:0000107		 RGD
Ensembl		 PMID:8638120 GO_REF:0000107 NCBI chr 3:29,424,620...29,432,637
Ensembl chr 3:9,027,425...9,034,480 		JBrowse link
somatotropin secreting cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrhr growth hormone releasing hormone receptor acts_upstream_of_or_within ISO
IEA		 MGI:1856425 (PMID:6116352), (PMID:6194978)
GO_REF:0000107		 RGD
Ensembl		 PMID:6116352 PMID:6194978 GO_REF:0000107 NCBI chr 4:85,830,345...85,863,127
Ensembl chr 4:84,500,212...84,532,776 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO MGI:2158737 (PMID:17015435) RGD PMID:17015435 NCBI chr11:16,763,312...16,781,295
Ensembl chr11:3,317,058...3,334,801 		JBrowse link
somatotropin secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO
IEA		 MGI:2385819 (PMID:8638120)
GO_REF:0000107		 RGD
Ensembl		 PMID:8638120 GO_REF:0000107 NCBI chr 3:29,424,620...29,432,637
Ensembl chr 3:9,027,425...9,034,480 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO MGI:1856024 (PMID:1334535), (PMID:6194978) RGD PMID:1334535 PMID:6194978 NCBI chr11:16,763,312...16,781,295
Ensembl chr11:3,317,058...3,334,801 		JBrowse link
G Prop1 PROP paired-like homeobox 1 acts_upstream_of_or_within ISO
IEA		 MGI:1856842 (PMID:6194978)
GO_REF:0000107		 RGD
Ensembl		 PMID:6194978 GO_REF:0000107 NCBI chr10:35,772,968...35,775,443
Ensembl chr10:35,271,973...35,274,434 		JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of_or_within ISO
IEA		 MGI:1857453 (PMID:18351662)
GO_REF:0000107		 RGD
Ensembl		 PMID:18351662 GO_REF:0000107 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
subthalamic nucleus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pitx2 paired-like homeodomain 2 acts_upstream_of_or_within ISO MGI:1857846 (PMID:18206388) RGD PMID:18206388 NCBI chr 2:217,717,738...217,737,293
Ensembl chr 2:217,717,693...217,737,293 		JBrowse link
subthalamus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII involved_in ISO
IEA		 (PMID:16901643)
GO_REF:0000107		 RGD
Ensembl		 PMID:16901643 GO_REF:0000107 NCBI chr10:38,086,691...38,093,871
Ensembl chr10:37,586,888...37,589,169 		JBrowse link
thalamus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 acts_upstream_of_or_within ISO MGI:4356167 (PMID:23527305) RGD PMID:23527305 NCBI chr 1:89,700,645...89,729,782
Ensembl chr 1:80,572,796...80,601,918 		JBrowse link
G Cntnap2 contactin associated protein 2 involved_in ISO
IEA		 (PMID:18179893)
GO_REF:0000107		 RGD
Ensembl		 PMID:18179893 GO_REF:0000107 NCBI chr 4:75,109,358...77,366,258
Ensembl chr 4:74,109,472...76,362,027 		JBrowse link
G Foxb1 forkhead box B1 involved_in ISO (PMID:11170346) RGD PMID:11170346 NCBI chr 8:70,407,221...70,409,841
Ensembl chr 8:70,408,186...70,409,781 		JBrowse link
G Gbx2 gastrulation brain homeobox 2 acts_upstream_of_or_within ISO
IEA		 MGI:1857634|MGI:3840448 (PMID:19279136)
GO_REF:0000107		 RGD
Ensembl		 PMID:19279136 GO_REF:0000107 NCBI chr 9:97,957,304...97,959,883
Ensembl chr 9:90,509,633...90,512,212 		JBrowse link
G Kiaa0319 KIAA0319 homolog acts_upstream_of_or_within ISO
IEA		 (PMID:35419947)
GO_REF:0000107		 RGD
Ensembl		 PMID:35419947 GO_REF:0000107 NCBI chr17:40,587,001...40,654,525
Ensembl chr17:40,165,084...40,225,653 		JBrowse link
G Kif5a kinesin family member 5A IEP RGD PMID:9349526 RGD:12792964 NCBI chr 7:64,937,210...64,974,339
Ensembl chr 7:63,049,424...63,092,858 		JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:2156191 (PMID:15342729) RGD PMID:15342729 NCBI chr 4:168,997,937...169,131,716
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
G Mecp2 methyl CpG binding protein 2 IEP RGD PMID:12605461 RGD:12790706 NCBI chr  X:156,932,481...156,995,981
Ensembl chr  X:151,789,930...151,844,689 		JBrowse link
G Ncam1 neural cell adhesion molecule 1 IDA RGD PMID:17292800 RGD:2326015 NCBI chr 8:58,762,088...59,062,131
Ensembl chr 8:49,865,633...50,166,014 		JBrowse link
G Ncor1 nuclear receptor co-repressor 1 acts_upstream_of_or_within ISO MGI:2677822 (PMID:11030619) RGD PMID:11030619 NCBI chr10:47,498,852...47,641,612
Ensembl chr10:46,999,536...47,141,032 		JBrowse link
G Ogdh oxoglutarate dehydrogenase involved_in IEA
ISO		 GO_REF:0000107
(PMID:16901643)		 Ensembl
RGD		 PMID:16901643 GO_REF:0000107 NCBI chr14:85,363,949...85,431,405
Ensembl chr14:81,150,091...81,217,479 		JBrowse link
G Olig2 oligodendrocyte transcription factor 2 acts_upstream_of_or_within ISO (PMID:19357274) RGD PMID:19357274 NCBI chr11:43,961,585...43,964,961
Ensembl chr11:30,475,398...30,480,152 		JBrowse link
G Ptchd1 patched domain containing 1 involved_in ISO
IEA		 (PMID:27007844)
GO_REF:0000107		 RGD
Ensembl		 PMID:27007844 GO_REF:0000107 NCBI chr  X:39,681,910...39,733,416
Ensembl chr  X:39,681,910...39,733,519 		JBrowse link
G Ptn pleiotrophin IEP RGD PMID:10051750 RGD:10043838 NCBI chr 4:66,260,764...66,342,614
Ensembl chr 4:65,293,734...65,375,456 		JBrowse link
G Shh sonic hedgehog signaling molecule acts_upstream_of_or_within ISO
IEA		 MGI:108075|MGI:1934268|MGI:2176173 (PMID:19357274)
GO_REF:0000107		 RGD
Ensembl		 PMID:19357274 GO_REF:0000107 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Smo smoothened, frizzled class receptor acts_upstream_of_or_within ISO
IEA		 MGI:2176173|MGI:3576373 (PMID:19357274)
GO_REF:0000107		 RGD
Ensembl		 PMID:19357274 GO_REF:0000107 NCBI chr 4:59,311,084...59,341,280
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IEP RGD PMID:8770891 RGD:4892048 NCBI chr 1:35,514,914...35,548,898
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Tal2 TAL bHLH transcription factor 2 acts_upstream_of_or_within ISO
IEA		 MGI:2684532 (PMID:11071772)
GO_REF:0000107		 RGD
Ensembl		 PMID:11071772 GO_REF:0000107 NCBI chr 5:73,206,372...73,212,929
Ensembl chr 5:68,411,012...68,417,569 		JBrowse link
G Uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII involved_in ISO
IEA		 (PMID:16901643)
GO_REF:0000107		 RGD
Ensembl		 PMID:16901643 GO_REF:0000107 NCBI chr10:38,086,691...38,093,871
Ensembl chr10:37,586,888...37,589,169 		JBrowse link
thyroid-stimulating hormone-secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 acts_upstream_of_or_within ISO
IEA		 (PMID:9463347)
GO_REF:0000107		 RGD
Ensembl		 PMID:9463347 GO_REF:0000107 NCBI chr 3:141,264,648...141,275,416
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Fgf2 fibroblast growth factor 2 acts_upstream_of_or_within ISO
IEA		 (PMID:9463347)
GO_REF:0000107		 RGD
Ensembl		 PMID:9463347 GO_REF:0000107 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO
IEA		 (PMID:9463347)
GO_REF:0000107		 RGD
Ensembl		 PMID:9463347 GO_REF:0000107 NCBI chr 1:254,533,504...254,539,605
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
G Gata2 GATA binding protein 2 acts_upstream_of_or_within ISO
IEA		 MGI:2179995|MGI:3628639 (PMID:16543408)
GO_REF:0000107		 RGD
Ensembl		 PMID:16543408 GO_REF:0000107 NCBI chr 4:122,211,501...122,225,058
Ensembl chr 4:120,658,986...120,667,761 		JBrowse link
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO
IEA		 MGI:2385819 (PMID:8638120)
GO_REF:0000107		 RGD
Ensembl		 PMID:8638120 GO_REF:0000107 NCBI chr 3:29,424,620...29,432,637
Ensembl chr 3:9,027,425...9,034,480 		JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of_or_within ISO
IEA		 MGI:1857453 (PMID:18351662)
GO_REF:0000107		 RGD
Ensembl		 PMID:18351662 GO_REF:0000107 NCBI chr 5:154,797,245...154,818,565
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    developmental process 7149
      anatomical structure development 6646
        diencephalon development 104
          cell migration in diencephalon 1
          determination of left/right asymmetry in diencephalon 0
          diencephalon morphogenesis + 6
          epithalamus development + 3
          globus pallidus development 4
          hypothalamus development + 37
          mammillary body development + 2
          pineal gland development 0
          pituitary gland development + 49
          subthalamus development + 2
          thalamus development + 20
Path 2
Term Annotations click to browse term
  biological_process 20558
    developmental process 7149
      anatomical structure development 6646
        multicellular organism development 5353
          system development 4635
            nervous system development 2872
              central nervous system development 1232
                brain development 907
                  forebrain development 560
                    diencephalon development 104
                      cell migration in diencephalon 1
                      determination of left/right asymmetry in diencephalon 0
                      diencephalon morphogenesis + 6
                      epithalamus development + 3
                      globus pallidus development 4
                      hypothalamus development + 37
                      mammillary body development + 2
                      pineal gland development 0
                      pituitary gland development + 49
                      subthalamus development + 2
                      thalamus development + 20
paths to the root