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ONTOLOGY REPORT - ANNOTATIONS

Term:pituitary gland development
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Accession:GO:0021983 term browser browse the term
Definition:The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.
Synonyms:related_synonym: hypophysis development


show annotations for term's descendants           Sort by:
pituitary gland development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1 adenylate cyclase activating polypeptide 1 IEP RGD PMID:18160680 RGD:2325274 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 IEP RGD PMID:17180597 RGD:2306413 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 IEP RGD PMID:17180597 RGD:2306413 NCBI chr 1:119,982,272...120,017,416
Ensembl chr 1:119,982,277...120,017,436 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857137 (MGI:1306869|PMID:9806931)		 Ensembl
RGD		 PMID:9806931 GO_REF:0000107 MGI:1306869 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A acts_upstream_of_or_within ISO MGI:2158342|MGI:2158390 (MGI:3709795|PMID:17359964) RGD PMID:17359964 MGI:3709795 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Cdh1 cadherin 1 IEP RGD PMID:17373711 RGD:2289637 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 acts_upstream_of_or_within ISO MGI:2176173|MGI:2181395 (MGI:3611103|PMID:16141355) RGD PMID:16141355 MGI:3611103 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor IEP RGD PMID:8946059 RGD:2313681 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (MGI:3688470|PMID:11062007) RGD PMID:11062007 MGI:3688470 NCBI chr 2:50,801,897...50,875,428
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Gata2 GATA binding protein 2 acts_upstream_of_or_within ISO MGI:2179995|MGI:3628639 (MGI:3625416|PMID:16543408) RGD PMID:16543408 MGI:3625416 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761 		JBrowse link
G Gli1 GLI family zinc finger 1 acts_upstream_of_or_within ISO MGI:95728 (MGI:1354188|PMID:10725236) RGD PMID:10725236 MGI:1354188 NCBI chr 7:63,156,926...63,169,579
Ensembl chr 7:63,156,926...63,169,251 		JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:95727 (MGI:1354188|PMID:10725236) RGD PMID:10725236 MGI:1354188 NCBI chr13:29,946,809...30,163,901
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 acts_upstream_of_or_within ISO MGI:104876|MGI:2149672 (MGI:3664138|PMID:17015435), (MGI:3712393|PMID:17426285) RGD PMID:17015435 PMID:17426285 MGI:3664138 MGI:3712393 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hesx1 HESX homeobox 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:102764|MGI:1931124|MGI:3822474|MGI:3822475 (MGI:1206234|PMID:9620767), (MGI:2154557|PMID:11731482), (MGI:3821506|PMID:18775421), (MGI:3821905|PMID:19093031), (MGI:4440397|PMID:20181723)
(PMID:26781211)		 RGD PMID:9620767 PMID:11731482 PMID:18775421 PMID:19093031 PMID:20181723 More... MGI:1206234 MGI:2154557 MGI:3821506 MGI:3821905 MGI:4440397, RGD:13792537 NCBI chr16:2,191,852...2,193,957
Ensembl chr16:2,191,852...2,193,957 		JBrowse link
G Hmga2 high mobility group AT-hook 2 acts_upstream_of_or_within ISO MGI:1856426 (MGI:54708|PMID:504232) RGD PMID:504232 MGI:54708 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Inhbb inhibin subunit beta B IEP RGD PMID:18160680 RGD:2325274 NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832 		JBrowse link
G Isl1 ISL LIM homeobox 1 acts_upstream_of_or_within ISO MGI:2182246 (MGI:1306869|PMID:9806931) RGD PMID:9806931 MGI:1306869 NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584 		JBrowse link
G Kdm1a lysine demethylase 1A acts_upstream_of_or_within ISO MGI:3711561 (MGI:3710033|PMID:17392792) RGD PMID:17392792 MGI:3710033 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO MGI:2385819 (MGI:3771226|PMID:18037398) RGD PMID:18037398 MGI:3771226 NCBI chr 3:9,026,432...9,035,122
Ensembl chr 3:9,027,425...9,034,480 		JBrowse link
G Msx1 msh homeobox 1 IEP RGD PMID:16451220 RGD:5132608 NCBI chr14:72,961,170...72,964,970
Ensembl chr14:72,961,148...72,964,966 		JBrowse link
G Nkx2-1 NK2 homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857494 (MGI:1306869|PMID:9806931)		 Ensembl
RGD		 PMID:9806931 GO_REF:0000107 MGI:1306869 NCBI chr 6:73,996,601...74,001,483
Ensembl chr 6:73,996,601...73,999,791 		JBrowse link
G Nog noggin involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1862000 (MGI:3709795|PMID:17359964)		 Ensembl
RGD		 PMID:17359964 GO_REF:0000107 MGI:3709795 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Pax6 paired box 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856155|MGI:1934347 (MGI:1350715|PMID:10588713)		 Ensembl
RGD		 PMID:10588713 GO_REF:0000107 MGI:1350715 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 IEP RGD PMID:15208361 RGD:2308902 NCBI chr 2:4,395,543...4,442,434
Ensembl chr 2:4,395,543...4,442,434 		JBrowse link
G Pitx1 paired-like homeodomain 1 acts_upstream_of_or_within ISO MGI:1934200 (MGI:1332284|PMID:10049363) RGD PMID:10049363 MGI:1332284 NCBI chr17:8,794,134...8,800,292
Ensembl chr17:8,794,134...8,800,291 		JBrowse link
G Pitx2 paired-like homeodomain 2 acts_upstream_of_or_within ISO MGI:1857844|MGI:1857846|MGI:2384494 (MGI:1344731|PMID:10498698), (MGI:1345532|PMID:10499586) RGD PMID:10498698 PMID:10499586 MGI:1344731 MGI:1345532 NCBI chr 2:217,717,738...217,737,293
Ensembl chr 2:217,717,693...217,737,293 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO MGI:1856024 (MGI:3625414|PMID:16556738) RGD PMID:16556738 MGI:3625414 NCBI chr11:3,316,818...3,334,804
Ensembl chr11:3,317,058...3,334,801 		JBrowse link
G Prop1 PROP paired-like homeobox 1 acts_upstream_of_or_within ISO MGI:1856842 (MGI:2154557|PMID:11731482) RGD PMID:11731482 MGI:2154557 NCBI chr10:35,271,959...35,274,434
Ensembl chr10:35,271,973...35,274,434 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region acts_upstream_of_or_within ISO MGI:3583755 (MGI:3664138|PMID:17015435) RGD PMID:17015435 MGI:3664138 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
G Sall1 spalt-like transcription factor 1 involved_in ISO (PMID:12065233) RGD PMID:12065233 NCBI chr19:18,005,782...18,022,705
Ensembl chr19:18,007,503...18,022,705 		JBrowse link
G Six3 SIX homeobox 3 acts_upstream_of_or_within
involved_in		 ISO MGI:96071 (MGI:3821506|PMID:18775421) RGD PMID:18775421 MGI:3821506 NCBI chr 6:9,040,123...9,043,336
Ensembl chr 6:9,036,434...9,053,301 		JBrowse link
G Sox2 SRY-box transcription factor 2 involved_in ISO (PMID:18285410) RGD PMID:18285410 NCBI chr 2:117,536,929...117,539,338
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Sox3 SRY-box transcription factor 3 involved_in ISO (MGI:3033563|PMID:14981518) RGD PMID:14981518 MGI:3033563 NCBI chr  X:139,308,608...139,310,734
Ensembl chr  X:139,309,329...139,310,678 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IEP RGD PMID:8770891 RGD:4892048 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Tbx19 T-box transcription factor 19 acts_upstream_of_or_within ISO (MGI:2137424|PMID:11447259) RGD PMID:11447259 MGI:2137424 NCBI chr13:77,450,848...77,484,475
Ensembl chr13:77,450,849...77,504,163 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO MGI:1926344 (MGI:3763872|PMID:17919533) RGD PMID:17919533 MGI:3763872 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967 		JBrowse link
adenohypophysis development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 acts_upstream_of_or_within ISO MGI:3576789 (MGI:3576468|PMID:9140068) RGD PMID:9140068 MGI:3576468 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Ghrh growth hormone releasing hormone acts_upstream_of_or_within TAS
ISO		 MGI:3051561 (MGI:3607618|PMID:15985453) RGD PMID:15985453 PMID:12511850 MGI:3607618, RGD:1601329 NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889 		JBrowse link
G Ghrhr growth hormone releasing hormone receptor acts_upstream_of_or_within ISO MGI:1856425 (MGI:51713|PMID:1504465), (MGI:54124|PMID:1270792), (MGI:63703|PMID:1329576) RGD PMID:1270792 PMID:1329576 PMID:1504465 MGI:51713 MGI:54124 MGI:63703 NCBI chr 4:84,498,159...84,532,847
Ensembl chr 4:84,500,212...84,532,776 		JBrowse link
G Gsx1 GS homeobox 1 acts_upstream_of_or_within ISO MGI:2154448 (MGI:79250|PMID:8631293) RGD PMID:8631293 MGI:79250 NCBI chr12:7,881,460...7,882,753
Ensembl chr12:7,881,460...7,882,753 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3808031 (MGI:3827091|PMID:18996108)		 Ensembl
RGD		 PMID:18996108 GO_REF:0000107 MGI:3827091 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 IMP RGD PMID:16216912 RGD:1601440 NCBI chr11:3,316,818...3,334,804
Ensembl chr11:3,317,058...3,334,801 		JBrowse link
G Prop1 PROP paired-like homeobox 1 acts_upstream_of_or_within ISO (MGI:3827091|PMID:18996108) RGD PMID:18996108 MGI:3827091 NCBI chr10:35,271,959...35,274,434
Ensembl chr10:35,271,973...35,274,434 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 acts_upstream_of_or_within ISO MGI:2386303 (MGI:894559|PMID:9247269) RGD PMID:9247269 MGI:894559 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Sox2 SRY-box transcription factor 2 acts_upstream_of_or_within IEP
ISO		 MGI:2449045 (MGI:3689142|PMID:16932809) RGD PMID:16932809 PMID:21815952 MGI:3689142, RGD:8661681 NCBI chr 2:117,536,929...117,539,338
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
adenohypophysis morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Duox2 dual oxidase 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3712359 (MGI:3712355|PMID:17440044)		 Ensembl
RGD		 PMID:17440044 GO_REF:0000107 MGI:3712355 NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902 		JBrowse link
corticotropin hormone secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:1202291|PMID:9463347)		 Ensembl
RGD		 PMID:9463347 GO_REF:0000107 MGI:1202291 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Fgf2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (MGI:1202291|PMID:9463347) RGD PMID:9463347 MGI:1202291 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO (MGI:1202291|PMID:9463347) RGD PMID:9463347 MGI:1202291 NCBI chr 1:244,584,477...244,590,359
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
hypophysis morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prop1 PROP paired-like homeobox 1 acts_upstream_of_or_within ISO MGI:3690463 (MGI:3690195|PMID:16678101) RGD PMID:16678101 MGI:3690195 NCBI chr10:35,271,959...35,274,434
Ensembl chr10:35,271,973...35,274,434 		JBrowse link
G Wnt5a Wnt family member 5A acts_upstream_of_or_within ISO MGI:1857617 (MGI:3043884|PMID:15037319) RGD PMID:15037319 MGI:3043884 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
neurohypophysis development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Otp orthopedia homeobox acts_upstream_of_or_within ISO MGI:2180541 (MGI:1347696|PMID:10557207) RGD PMID:10557207 MGI:1347696 NCBI chr 2:26,108,158...26,116,359
Ensembl chr 2:26,108,163...26,116,359 		JBrowse link
G Pou3f2 POU class 3 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857996 (MGI:77941|PMID:8543156)		 Ensembl
RGD		 PMID:8543156 GO_REF:0000107 MGI:77941 NCBI chr 5:36,077,930...36,083,838
Ensembl chr 5:36,077,930...36,083,838 		JBrowse link
prolactin secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO MGI:2385819 (MGI:80537|PMID:8638120) RGD PMID:8638120 MGI:80537 NCBI chr 3:9,026,432...9,035,122
Ensembl chr 3:9,027,425...9,034,480 		JBrowse link
somatotropin secreting cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ghrhr growth hormone releasing hormone receptor acts_upstream_of_or_within ISO MGI:1856425 (MGI:55682|PMID:6194978), (MGI:63474|PMID:6116352) RGD PMID:6116352 PMID:6194978 MGI:55682 MGI:63474 NCBI chr 4:84,498,159...84,532,847
Ensembl chr 4:84,500,212...84,532,776 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO MGI:2158737 (MGI:3664138|PMID:17015435) RGD PMID:17015435 MGI:3664138 NCBI chr11:3,316,818...3,334,804
Ensembl chr11:3,317,058...3,334,801 		JBrowse link
somatotropin secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO MGI:2385819 (MGI:80537|PMID:8638120) RGD PMID:8638120 MGI:80537 NCBI chr 3:9,026,432...9,035,122
Ensembl chr 3:9,027,425...9,034,480 		JBrowse link
G Pou1f1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO MGI:1856024 (MGI:55682|PMID:6194978), (MGI:80583|PMID:1334535) RGD PMID:1334535 PMID:6194978 MGI:55682 MGI:80583 NCBI chr11:3,316,818...3,334,804
Ensembl chr11:3,317,058...3,334,801 		JBrowse link
G Prop1 PROP paired-like homeobox 1 acts_upstream_of_or_within ISO MGI:1856842 (MGI:55682|PMID:6194978) RGD PMID:6194978 MGI:55682 NCBI chr10:35,271,959...35,274,434
Ensembl chr10:35,271,973...35,274,434 		JBrowse link
G Wnt4 Wnt family member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857453 (MGI:3777488|PMID:18351662)		 Ensembl
RGD		 PMID:18351662 GO_REF:0000107 MGI:3777488 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
thyroid-stimulating hormone-secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:1202291|PMID:9463347)		 Ensembl
RGD		 PMID:9463347 GO_REF:0000107 MGI:1202291 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Fgf2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (MGI:1202291|PMID:9463347) RGD PMID:9463347 MGI:1202291 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO (MGI:1202291|PMID:9463347) RGD PMID:9463347 MGI:1202291 NCBI chr 1:244,584,477...244,590,359
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
G Gata2 GATA binding protein 2 acts_upstream_of_or_within ISO MGI:2179995|MGI:3628639 (MGI:3625416|PMID:16543408) RGD PMID:16543408 MGI:3625416 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761 		JBrowse link
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO MGI:2385819 (MGI:80537|PMID:8638120) RGD PMID:8638120 MGI:80537 NCBI chr 3:9,026,432...9,035,122
Ensembl chr 3:9,027,425...9,034,480 		JBrowse link
G Wnt4 Wnt family member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857453 (MGI:3777488|PMID:18351662)		 Ensembl
RGD		 PMID:18351662 GO_REF:0000107 MGI:3777488 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19748
    developmental process 6931
      anatomical structure development 6386
        diencephalon development 101
          pituitary gland development 49
            adenohypophysis development + 16
            hypophysis morphogenesis + 3
            neurohypophysis development + 2
Path 2
Term Annotations click to browse term
  biological_process 19748
    developmental process 6931
      anatomical structure development 6386
        multicellular organism development 5165
          system development 4436
            nervous system development 2706
              central nervous system development 1190
                brain development 890
                  forebrain development 549
                    diencephalon development 101
                      pituitary gland development 49
                        adenohypophysis development + 16
                        hypophysis morphogenesis + 3
                        neurohypophysis development + 2
paths to the root