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ONTOLOGY REPORT - ANNOTATIONS

Term:thyroid-stimulating hormone-secreting cell differentiation
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Accession:GO:0060129 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a thyroid-stimulating hormone-secreting cell. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid-stimulating hormone, thyrotrophin.
Synonyms:exact_synonym: TSH-secreting cell differentiation;   beta-basophil differentiation;   thyrotrope differentiation;   thyrotroph differentiation


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thyroid-stimulating hormone-secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:9463347)		 Ensembl
RGD		 PMID:9463347 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Fgf2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (PMID:9463347) RGD PMID:9463347 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO (PMID:9463347) RGD PMID:9463347 NCBI chr 1:244,584,477...244,590,578
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
G Gata2 GATA binding protein 2 acts_upstream_of_or_within ISO MGI:2179995|MGI:3628639 (PMID:16543408) RGD PMID:16543408 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761 		JBrowse link
G Lhx3 LIM homeobox 3 acts_upstream_of_or_within ISO MGI:2385819 (PMID:8638120) RGD PMID:8638120 NCBI chr 3:9,026,432...9,035,122
Ensembl chr 3:9,027,425...9,034,480 		JBrowse link
G Wnt4 Wnt family member 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1857453 (PMID:18351662)
GO_REF:0000107		 RGD
Ensembl		 PMID:18351662 GO_REF:0000107 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20075
    developmental process 7069
      anatomical structure development 6572
        adenohypophysis development 16
          thyroid-stimulating hormone-secreting cell differentiation 6
            thyroid-stimulating hormone-secreting cell development 0
Path 2
Term Annotations click to browse term
  biological_process 20075
    developmental process 7069
      anatomical structure development 6572
        multicellular organism development 5298
          system development 4583
            nervous system development 2847
              central nervous system development 1212
                brain development 905
                  forebrain development 559
                    diencephalon development 104
                      pituitary gland development 49
                        adenohypophysis development 16
                          thyroid-stimulating hormone-secreting cell differentiation 6
                            thyroid-stimulating hormone-secreting cell development 0
paths to the root