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ONTOLOGY REPORT - ANNOTATIONS

Term:hypothalamus development
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Accession:GO:0021854 term browser browse the term
Definition:The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state.

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hypothalamus development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857429 (MGI:3054131|PMID:15342910)		 Ensembl
RGD		 PMID:15342910 GO_REF:0000107 MGI:3054131 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Crh corticotropin releasing hormone IEP RGD PMID:20002962 RGD:5130950 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IEP RGD PMID:20002962 RGD:5130950 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645 		JBrowse link
G Crhr2 corticotropin releasing hormone receptor 2 IEP RGD PMID:20002962 RGD:5130950 NCBI chr 4:85,286,371...85,329,374
Ensembl chr 4:85,286,372...85,329,362 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 IEP RGD PMID:15804399 RGD:4891928 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408 		JBrowse link
G Esr2 estrogen receptor 2 IEP RGD PMID:12960049 RGD:1582276 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251 		JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor IEP RGD PMID:8946059 RGD:2313681 NCBI chr 8:33,756,634...33,879,625
Ensembl chr 8:33,816,386...33,879,625 		JBrowse link
G Gsx1 GS homeobox 1 acts_upstream_of_or_within ISO MGI:2154448 (MGI:79250|PMID:8631293) RGD PMID:8631293 MGI:79250 NCBI chr12:9,605,873...9,607,168
Ensembl chr12:9,605,873...9,607,168 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor IEP RGD PMID:23291449 RGD:7207858 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240 		JBrowse link
G Ncoa1 nuclear receptor coactivator 1 IEP RGD PMID:12551846 RGD:5688241 NCBI chr 6:28,677,563...28,931,844
Ensembl chr 6:28,677,540...28,931,843 		JBrowse link
G Nkx2-6 NK2 homeobox 6 acts_upstream_of_or_within ISO (PMID:9621431) RGD PMID:9621431 NCBI chr15:51,034,620...51,038,715
Ensembl chr15:51,034,620...51,038,704 		JBrowse link
G Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1 involved_in ISO
IEA		 (PMID:20512159)
GO_REF:0000107		 RGD
Ensembl		 PMID:20512159 GO_REF:0000107 NCBI chr13:44,578,208...44,649,876
Ensembl chr13:44,615,553...44,648,620 		JBrowse link
G Rax retina and anterior neural fold homeobox involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856862 (MGI:54368|PMID:925203)		 Ensembl
RGD		 PMID:925203 GO_REF:0000107 MGI:54368 NCBI chr18:61,638,352...61,642,056
Ensembl chr18:61,638,352...61,642,056 		JBrowse link
G Reln reelin IEP RGD PMID:10436054 RGD:634730 NCBI chr 4:9,347,533...9,774,257
Ensembl chr 4:9,347,528...9,773,670 		JBrowse link
G Sox3 SRY-box transcription factor 3 involved_in ISO (MGI:3033563|PMID:14981518) RGD PMID:14981518 MGI:3033563 NCBI chr  X:144,035,162...144,037,364
Ensembl chr  X:144,035,883...144,037,294 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 IEP RGD PMID:15804399, PMID:8770891 RGD:4891928, RGD:4892048 NCBI chr 1:36,320,504...36,354,694
Ensembl chr 1:36,320,461...36,354,756 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 IEP RGD PMID:15804399 RGD:4891928 NCBI chr 6:25,279,635...25,315,501
Ensembl chr 6:25,279,626...25,315,511 		JBrowse link
G Uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII acts_upstream_of_or_within ISO (PMID:16901643) RGD PMID:16901643 NCBI chr10:38,779,132...38,782,489
Ensembl chr10:38,779,132...38,782,419 		JBrowse link
gonadotrophin-releasing hormone neuronal migration to the hypothalamus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ndnf neuron-derived neurotrophic factor involved_in ISO (MGI:6442643|PMID:31883645) RGD PMID:31883645 MGI:6442643 NCBI chr 4:96,528,830...96,565,780 JBrowse link
G Nrp1 neuropilin 1 involved_in ISO (MGI:4850173|PMID:21059704) RGD PMID:21059704 MGI:4850173 NCBI chr19:61,332,351...61,486,166
Ensembl chr19:61,332,351...61,485,858 		JBrowse link
G Nrp2 neuropilin 2 involved_in ISO (MGI:4850173|PMID:21059704) RGD PMID:21059704 MGI:4850173 NCBI chr 9:69,496,875...69,609,802
Ensembl chr 9:69,497,121...69,612,087 		JBrowse link
G Sema3a semaphorin 3A involved_in ISO (MGI:4850173|PMID:21059704) RGD PMID:21059704 MGI:4850173 NCBI chr 4:18,170,375...18,545,190
Ensembl chr 4:18,178,656...18,396,035 		JBrowse link
hypothalamus cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hap1 huntingtin-associated protein 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5560429|PMID:24355921)		 Ensembl
RGD		 PMID:24355921 GO_REF:0000107 MGI:5560429 NCBI chr10:88,257,975...88,266,210
Ensembl chr10:88,257,976...88,266,210 		JBrowse link
G Otp orthopedia homeobox acts_upstream_of_or_within ISO MGI:2180541 (MGI:1347696|PMID:10557207) RGD PMID:10557207 MGI:1347696 NCBI chr 2:24,546,393...24,554,953
Ensembl chr 2:24,546,536...24,554,683 		JBrowse link
G Pou3f2 POU class 3 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857996 (MGI:77941|PMID:8543156)		 Ensembl
RGD		 PMID:8543156 GO_REF:0000107 MGI:77941 NCBI chr 5:36,677,452...36,683,356
Ensembl chr 5:36,681,528...36,683,356 		JBrowse link
G Prop1 PROP paired-like homeobox 1 acts_upstream_of_or_within ISO MGI:1856842 (MGI:85929|PMID:9067988) RGD PMID:9067988 MGI:85929 NCBI chr10:36,449,920...36,452,381
Ensembl chr10:36,449,920...36,452,378 		JBrowse link
hypothalamus cell migration term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxb1 forkhead box B1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4887555|PMID:19046377)		 UniProt
RGD		 PMID:19046377 GO_REF:0000024 MGI:4887555 NCBI chr 8:75,992,751...75,995,371
Ensembl chr 8:75,992,755...75,995,371 		JBrowse link
G Pitx2 paired-like homeodomain 2 acts_upstream_of_or_within ISO MGI:1857846 (MGI:3790896|PMID:18206388) RGD PMID:18206388 MGI:3790896 NCBI chr 2:233,602,732...233,621,059
Ensembl chr 2:233,602,732...233,621,129 		JBrowse link
hypothalamus gonadotrophin-releasing hormone neuron development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nhlh2 nescient helix loop helix 2 involved_in
acts_upstream_of_or_within_positive_effect		 IEA
ISO		 GO_REF:0000107
(MGI:5504302|PMID:23785158)		 Ensembl
RGD		 PMID:23785158 GO_REF:0000107 MGI:5504302 NCBI chr 2:204,427,577...204,432,946
Ensembl chr 2:204,427,608...204,432,946 		JBrowse link
G Ubb ubiquitin B acts_upstream_of_or_within ISO MGI:3774112 (MGI:3776935|PMID:18299572) RGD PMID:18299572 MGI:3776935 NCBI chr10:48,880,231...48,881,896
Ensembl chr10:48,881,049...48,881,881 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19612
    developmental process 6792
      anatomical structure development 6265
        hypothalamus development 30
          hypothalamus cell differentiation + 10
          hypothalamus cell migration + 6
Path 2
Term Annotations click to browse term
  biological_process 19612
    developmental process 6792
      anatomical structure development 6265
        multicellular organism development 5747
          system development 5290
            nervous system development 2718
              central nervous system development 1266
                brain development 972
                  forebrain development 509
                    diencephalon development 96
                      hypothalamus development 30
                        hypothalamus cell differentiation + 10
                        hypothalamus cell migration + 6
paths to the root