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ONTOLOGY REPORT - ANNOTATIONS

Term:odontogenesis of dentin-containing tooth
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Accession:GO:0042475 term browser browse the term
Definition:The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel.
Comment:Note that placoid scales found in the cartilaginous fishes presumably develop through the same processes, but are found on the dermis, rather than in the mouth or pharynx. See Wikipedia:Placoid_scale#Placoid_scales.
Synonyms:exact_synonym: odontogenesis of dentine-containing teeth;   odontogenesis of dentine-containing tooth
 broad_synonym: odontogeny;   odontosis;   tooth development
 only_in_taxon: NCBITaxon:7711 ! Chordata


show annotations for term's descendants           Sort by:
odontogenesis of dentin-containing tooth term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr2a activin A receptor type 2A involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:87912 (PMID:16330774)		 Ensembl
RGD		 PMID:16330774 GO_REF:0000107 NCBI chr 3:33,204,961...33,292,673
Ensembl chr 3:33,205,523...33,289,968 		JBrowse link
G Acvr2b activin A receptor type 2B involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:102806|MGI:1857709|MGI:2179547 (PMID:11714685), (PMID:16330774)		 Ensembl
RGD		 PMID:11714685 PMID:16330774 GO_REF:0000107 NCBI chr 8:119,138,901...119,178,477
Ensembl chr 8:119,138,812...119,170,458 		JBrowse link
G Adm adrenomedullin IEP RGD PMID:19828015 RGD:2325629 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Ambn ameloblastin involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:19,601,761...19,614,382
Ensembl chr14:19,601,702...19,614,393 		JBrowse link
G Amelx amelogenin, X-linked involved_in ISO (MGI:3828400|PMID:16674683) RGD PMID:16674683 MGI:3828400 NCBI chr  X:25,076,362...25,087,660
Ensembl chr  X:25,076,362...25,087,660 		JBrowse link
G Amtn amelotin involved_in IEP
IBA
ISO
IEA		 PMID:16787391
GO_REF:0000033
(MGI:3617591|PMID:16304441)
GO_REF:0000002
PMID:16674676		 GO_Central
RGD
InterPro		 PMID:16304441 PMID:16787391 PMID:16674676 GO_REF:0000002 GO_REF:0000033 MGI:3617591, RGD:2304068, RGD:8554564 NCBI chr14:19,648,624...19,661,181
Ensembl chr14:19,648,625...19,661,181 		JBrowse link
G Ankrd11 ankyrin repeat domain containing 11 acts_upstream_of_or_within ISO (PMID:21782149) RGD PMID:21782149 NCBI chr19:50,940,284...51,098,962
Ensembl chr19:50,940,299...51,098,962 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator acts_upstream_of_or_within ISO MGI:1197519 (PMID:15967824) RGD PMID:15967824 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl11b BCL11 transcription factor B acts_upstream_of_or_within ISO MGI:3839578 (PMID:19251658) RGD PMID:19251658 NCBI chr 6:126,834,531...126,927,720
Ensembl chr 6:126,834,531...126,928,224 		JBrowse link
G Bcl2l11 Bcl2-like 11 acts_upstream_of_or_within ISO MGI:99702 (PMID:15967824) RGD PMID:15967824 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:15525533)		 Ensembl
RGD		 PMID:15525533 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1913292 (PMID:15525533), (PMID:16179481)		 Ensembl
RGD		 PMID:15525533 PMID:16179481 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bmp7 bone morphogenetic protein 7 acts_upstream_of_or_within ISO (PMID:15525533) RGD PMID:15525533 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A acts_upstream_of_or_within ISO MGI:2158390|MGI:2176835 (PMID:15716346) RGD PMID:15716346 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Bsg basigin (Ok blood group) IEP RGD PMID:17684756 RGD:2289060 NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387 		JBrowse link
G Car2 carbonic anhydrase 2 IEP RGD PMID:8766158 RGD:1600721 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Ccdc154 coiled-coil domain containing 154 acts_upstream_of_or_within ISO MGI:5702426 (PMID:20121924) RGD PMID:20121924 NCBI chr10:14,177,271...14,187,378
Ensembl chr10:14,177,278...14,187,253 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex acts_upstream_of_or_within ISO MGI:3039784 (PMID:14960276) RGD PMID:14960276 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Ctnna1 catenin alpha 1 IEP RGD PMID:10681393 RGD:2289810 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910 		JBrowse link
G Ctnnb1 catenin beta 1 acts_upstream_of_or_within
involved_in		 IEP
ISO
IEA		 MGI:1858008 (PMID:15866165)
GO_REF:0000107		 RGD
Ensembl		 PMID:15866165 PMID:10681393 GO_REF:0000107, RGD:2289810 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Dlx1 distal-less homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:94902 (PMID:9187081)		 Ensembl
RGD		 PMID:9187081 GO_REF:0000107 NCBI chr 3:56,356,190...56,360,780
Ensembl chr 3:56,356,190...56,360,780 		JBrowse link
G Dlx2 distal-less homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:94901 (PMID:9187081)		 Ensembl
RGD		 PMID:9187081 GO_REF:0000107 NCBI chr 3:56,370,238...56,373,581
Ensembl chr 3:56,370,483...56,373,597 		JBrowse link
G Dlx3 distal-less homeobox 3 acts_upstream_of_or_within ISO MGI:2386570|MGI:3813133 (PMID:22351765) RGD PMID:22351765 NCBI chr10:80,064,489...80,069,891
Ensembl chr10:80,064,489...80,069,872 		JBrowse link
G Dspp dentin sialophosphoprotein IEP RGD PMID:15533758 RGD:1599800 NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672 		JBrowse link
G Eda ectodysplasin-A involved_in
acts_upstream_of_or_within		 ISO (PMID:27144394)
MGI:1856197 (PMID:10610025), (PMID:5893447)		 RGD PMID:5893447 PMID:10610025 PMID:27144394 NCBI chr  X:65,078,454...65,480,172
Ensembl chr  X:65,078,673...65,480,172 		JBrowse link
G Edar ectodysplasin-A receptor acts_upstream_of_or_within ISO MGI:1856017 (PMID:544312) RGD PMID:544312 NCBI chr20:26,587,836...26,666,543
Ensembl chr20:26,587,839...26,666,494 		JBrowse link
G Edaradd EDAR associated via death domain acts_upstream_of_or_within ISO MGI:1856832 (PMID:14699584), (PMID:5893447) RGD PMID:5893447 PMID:14699584 NCBI chr17:85,866,629...85,910,612
Ensembl chr17:85,656,905...85,910,447 		JBrowse link
G Enam enamelin acts_upstream_of_or_within ISO MGI:3512772 (PMID:15271968) RGD PMID:15271968 NCBI chr14:19,556,729...19,581,433
Ensembl chr14:19,556,729...19,581,425 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (PMID:11062007), (PMID:11880361) RGD PMID:11062007 PMID:11880361 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fgf4 fibroblast growth factor 4 acts_upstream_of_or_within ISO (PMID:12502739) RGD PMID:12502739 NCBI chr 1:200,023,937...200,027,793
Ensembl chr 1:200,024,056...200,025,466 		JBrowse link
G Foxc1 forkhead box C1 involved_in ISO (PMID:12614756) RGD PMID:12614756 NCBI chr17:32,631,379...32,635,361
Ensembl chr17:32,633,142...32,634,803 		JBrowse link
G Foxi3 forkhead box I3 involved_in ISO (PMID:28710361) RGD PMID:28710361 NCBI chr 4:102,933,487...102,937,655
Ensembl chr 4:102,933,409...102,937,655 		JBrowse link
G Fst follistatin acts_upstream_of_or_within ISO MGI:1857467 (PMID:15305290), (PMID:15525533) RGD PMID:15305290 PMID:15525533 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571 		JBrowse link
G Gata6 GATA binding protein 6 IEP RGD PMID:17923110 RGD:2314196 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:1857509|MGI:95729 (PMID:9655803) RGD PMID:9655803 NCBI chr13:29,946,882...30,163,589
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:95728 (PMID:9655803) RGD PMID:9655803 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Gnao1 G protein subunit alpha o1 IEP RGD PMID:28706494 RGD:13513970 NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493 		JBrowse link
G Hand1 heart and neural crest derivatives expressed 1 acts_upstream_of_or_within ISO MGI:103580 (PMID:17764670) RGD PMID:17764670 NCBI chr10:42,006,646...42,009,213
Ensembl chr10:42,006,651...42,009,213 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:103577 (PMID:17764670)		 Ensembl
RGD		 PMID:17764670 GO_REF:0000107 NCBI chr16:32,917,448...32,920,791
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Hdac1 histone deacetylase 1 involved_in ISO UniProtKB:P70288 (MGI:4889029|PMID:21093383) RGD PMID:21093383 MGI:4889029 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111 		JBrowse link
G Hdac2 histone deacetylase 2 involved_in ISO UniProtKB:O09106 (MGI:4889029|PMID:21093383) RGD PMID:21093383 MGI:4889029 NCBI chr20:40,548,244...40,571,609
Ensembl chr20:40,548,250...40,571,609 		JBrowse link
G Itga6 integrin subunit alpha 6 acts_upstream_of_or_within ISO (PMID:16365040) RGD PMID:16365040 NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428 		JBrowse link
G Jag2 jagged canonical Notch ligand 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2657215 (PMID:15721140)		 Ensembl
RGD		 PMID:15721140 GO_REF:0000107 NCBI chr 6:131,983,059...132,005,665
Ensembl chr 6:131,983,056...132,005,818 		JBrowse link
G Lama5 laminin subunit alpha 5 acts_upstream_of_or_within ISO MGI:1934917 (PMID:16365040) RGD PMID:16365040 NCBI chr 3:167,270,296...167,318,370
Ensembl chr 3:167,270,296...167,318,451 		JBrowse link
G Lef1 lymphoid enhancer binding factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1202879|MGI:1926601 (PMID:12502739), (PMID:15649466), (PMID:17699607)		 Ensembl
RGD		 PMID:12502739 PMID:15649466 PMID:17699607 GO_REF:0000107 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794 		JBrowse link
G Lhx8 LIM homeobox 8 acts_upstream_of_or_within ISO (PMID:12703558) RGD PMID:12703558 NCBI chr 2:243,244,958...243,269,624
Ensembl chr 2:243,244,961...243,269,416 		JBrowse link
G Lrp4 LDL receptor related protein 4 acts_upstream_of_or_within ISO MGI:2661383|MGI:3580702 (PMID:17119023) RGD PMID:17119023 NCBI chr 3:77,429,600...77,483,593
Ensembl chr 3:77,429,798...77,483,593 		JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO MGI:1861309 (PMID:5893447), (PMID:591875) RGD PMID:591875 PMID:5893447 MGI:61211 MGI:61254 NCBI chr 4:167,269,856...167,400,364
Ensembl chr 4:167,270,353...167,400,497 		JBrowse link
G Msx1 msh homeobox 1 involved_in ISO (PMID:10742093), (PMID:11369996), (PMID:8696335)
(MGI:3688967|PMID:11369996)		 RGD PMID:8696335 PMID:10742093 PMID:11369996 MGI:3688967 NCBI chr14:72,961,036...72,964,970
Ensembl chr14:72,961,148...72,964,966 		JBrowse link
G Nf2 NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1926957 (PMID:10887156)		 Ensembl
RGD		 PMID:10887156 GO_REF:0000107 NCBI chr14:79,627,399...79,710,709
Ensembl chr14:79,627,399...79,710,667 		JBrowse link
G Nfic nuclear factor I/C acts_upstream_of_or_within ISO MGI:2450153 (PMID:12529411) RGD PMID:12529411 NCBI chr 7:8,278,210...8,309,936
Ensembl chr 7:8,253,361...8,309,936 		JBrowse link
G Ngfr nerve growth factor receptor involved_in
acts_upstream_of		 IEA
ISO		 GO_REF:0000107
MGI:1857226 (PMID:9268129)		 Ensembl
RGD		 PMID:9268129 GO_REF:0000107 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nkx2-3 NK2 homeobox 3 acts_upstream_of_or_within ISO MGI:2448069 (PMID:12141427) RGD PMID:12141427 NCBI chr 1:242,478,130...242,481,083
Ensembl chr 1:242,478,130...242,481,083 		JBrowse link
G Odam odontogenic, ameloblast associated involved_in ISO
IBA
IEA		 (PMID:16674676)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:16674676 GO_REF:0000033 GO_REF:0000107 NCBI chr14:20,193,286...20,202,517
Ensembl chr14:20,193,302...20,202,517 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1926728 (PMID:15543606)		 Ensembl
RGD		 PMID:15543606 GO_REF:0000107 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pitx2 paired-like homeodomain 2 IEP RGD PMID:16416307 RGD:2289007 NCBI chr 2:217,717,738...217,737,293
Ensembl chr 2:217,717,693...217,737,293 		JBrowse link
G Rogdi rogdi atypical leucine zipper involved_in ISO (PMID:25565929) RGD PMID:25565929 NCBI chr10:10,567,834...10,572,453
Ensembl chr10:10,567,834...10,572,452 		JBrowse link
G Runx2 RUNX family transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2176465 (PMID:15136142), (PMID:15668330)		 Ensembl
RGD		 PMID:15136142 PMID:15668330 GO_REF:0000107 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Scn10a sodium voltage-gated channel alpha subunit 10 IEP RGD PMID:21640979 RGD:6484223 NCBI chr 8:119,350,723...119,462,882
Ensembl chr 8:119,350,724...119,462,614 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 IEP RGD PMID:21640979 RGD:6484223 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1934268|MGI:2445832 (PMID:11044393)		 Ensembl
RGD		 PMID:11044393 GO_REF:0000107 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Smo smoothened, frizzled class receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1934268|MGI:2176256|MGI:2445832 (PMID:12403705), (PMID:17199044)		 Ensembl
RGD		 PMID:12403705 PMID:17199044 GO_REF:0000107 NCBI chr 4:58,343,626...58,373,823
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Sostdc1 sclerostin domain containing 1 acts_upstream_of_or_within ISO MGI:3604658|MGI:88180 (PMID:16179481) RGD PMID:16179481 NCBI chr 6:53,051,336...53,055,510
Ensembl chr 6:53,051,354...53,055,579 		JBrowse link
G Tbx1 T-box transcription factor 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:2179136 (PMID:19233155), (PMID:20816801)		 UniProt
RGD		 PMID:19233155 PMID:20816801 GO_REF:0000024 NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO MGI:96770 (PMID:17699607) RGD PMID:17699607 NCBI chr 1:254,785,956...254,978,967
Ensembl chr 1:254,786,091...254,978,967 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 IEP RGD PMID:29175126 RGD:14995479 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnc tenascin C IEP RGD PMID:12971948 RGD:4889616 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624 		JBrowse link
G Tp63 tumor protein p63 acts_upstream_of_or_within ISO MGI:1934269|MGI:1934580 (PMID:16410075), (PMID:16524929) RGD PMID:16410075 PMID:16524929 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
G Traf6 TNF receptor associated factor 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2675469 (PMID:14699584)		 Ensembl
RGD		 PMID:14699584 GO_REF:0000107 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Wnt6 Wnt family member 6 involved_in ISO (PMID:20113781) RGD PMID:20113781 NCBI chr 9:76,329,882...76,343,523
Ensembl chr 9:76,329,882...76,343,523 		JBrowse link
G Wnt7b Wnt family member 7B acts_upstream_of_or_within ISO (PMID:10781055) RGD PMID:10781055 NCBI chr 7:116,634,817...116,679,459
Ensembl chr 7:116,634,814...116,679,581 		JBrowse link
amelogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amelx amelogenin, X-linked involved_in ISO (MGI:6716964|PMID:26403673) RGD PMID:26403673 MGI:6716964 NCBI chr  X:25,076,362...25,087,660
Ensembl chr  X:25,076,362...25,087,660 		JBrowse link
G Ascl5 achaete-scute family bHLH transcription factor 5 involved_in ISO (MGI:6305509|PMID:30504223), (MGI:7280983|PMID:34812512) RGD PMID:30504223 PMID:34812512 MGI:6305509 MGI:7280983 NCBI chr13:47,491,799...47,493,269
Ensembl chr13:47,492,026...47,492,592 		JBrowse link
G Atf2 activating transcription factor 2 IDA RGD PMID:15218628 RGD:10053659 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Cftr CF transmembrane conductance regulator involved_in IEA
ISO		 GO_REF:0000107
(MGI:6716964|PMID:26403673)		 Ensembl
RGD		 PMID:26403673 GO_REF:0000107 MGI:6716964 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Csf3r colony stimulating factor 3 receptor IEP RGD PMID:10206335 RGD:5134351 NCBI chr 5:138,298,605...138,318,224
Ensembl chr 5:138,301,506...138,317,881 		JBrowse link
G Dspp dentin sialophosphoprotein acts_upstream_of_or_within ISO MGI:2653208 (PMID:25027178) RGD PMID:25027178 NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672 		JBrowse link
G Enam enamelin involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:3055582|MGI:3055586|MGI:3055587|MGI:3796583 (PMID:15649948), (PMID:18252720), (PMID:22813216), (PMID:24603688)		 GO_Central
RGD		 PMID:15649948 PMID:18252720 PMID:22813216 PMID:24603688 GO_REF:0000033 NCBI chr14:19,556,729...19,581,433
Ensembl chr14:19,556,729...19,581,425 		JBrowse link
G Klk4 kallikrein-related peptidase 4 involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:15235027)
MGI:4355346 (PMID:19578120), (PMID:21454549), (PMID:22243248)
GO_REF:0000033		 RGD
GO_Central		 PMID:15235027 PMID:19578120 PMID:21454549 PMID:22243248 GO_REF:0000033 NCBI chr 1:94,344,195...94,349,425
Ensembl chr 1:94,344,195...94,349,424 		JBrowse link
G Klk5 kallikrein related-peptidase 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:94,296,574...94,304,768
Ensembl chr 1:94,296,168...94,304,666 		JBrowse link
G Mmp20 matrix metallopeptidase 20 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:2447874 (PMID:15557396), (PMID:21454549), (PMID:22243248)		 GO_Central
RGD		 PMID:15557396 PMID:21454549 PMID:22243248 GO_REF:0000033 NCBI chr 8:4,789,415...4,830,035
Ensembl chr 8:4,789,415...4,830,035 		JBrowse link
G Perp p53 apoptosis effector related to PMP22 acts_upstream_of_or_within ISO MGI:2683069 (PMID:21285247) RGD PMID:21285247 NCBI chr 1:13,542,067...13,554,514
Ensembl chr 1:13,542,067...13,554,511 		JBrowse link
G Relt RELT, TNF receptor involved_in ISO
IBA		 (PMID:30506946)
GO_REF:0000033
(MGI:6368096|PMID:30506946)		 RGD
GO_Central		 PMID:30506946 GO_REF:0000033 MGI:6368096 NCBI chr 1:155,206,976...155,224,609
Ensembl chr 1:155,206,976...155,214,196 		JBrowse link
G Rogdi rogdi atypical leucine zipper acts_upstream_of_or_within ISO (PMID:38172607) RGD PMID:38172607 NCBI chr10:10,567,834...10,572,453
Ensembl chr10:10,567,834...10,572,452 		JBrowse link
G Slc24a4 solute carrier family 24 member 4 involved_in ISO (MGI:5520028|PMID:23375655), (MGI:6716966|PMID:27752731) RGD PMID:23375655 PMID:27752731 MGI:5520028 MGI:6716966 NCBI chr 6:121,279,590...121,419,811
Ensembl chr 6:121,280,031...121,414,949 		JBrowse link
G Slc4a2 solute carrier family 4 member 2 involved_in ISO (MGI:6716964|PMID:26403673) RGD PMID:26403673 MGI:6716964 NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965 		JBrowse link
G Wdr72 WD repeat domain 72 acts_upstream_of_or_within ISO (PMID:35181734) RGD PMID:35181734 NCBI chr 8:74,838,338...75,020,938
Ensembl chr 8:74,838,318...75,018,229 		JBrowse link
dentin mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 acts_upstream_of_or_within ISO MGI:1856973 (PMID:23174213) RGD PMID:23174213 NCBI chr 1:201,127,034...201,138,787
Ensembl chr 1:201,127,034...201,138,742 		JBrowse link
dentinogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dspp dentin sialophosphoprotein involved_in
acts_upstream_of_or_within		 IEP
IBA
ISO		 GO_REF:0000033
MGI:2653208 (PMID:25027178)		 GO_Central
RGD		 PMID:25027178 PMID:24502800 GO_REF:0000033, RGD:12911210 NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672 		JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase acts_upstream_of_or_within ISO MGI:5432377 (PMID:22732358) RGD PMID:22732358 NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543 		JBrowse link
G Htra1 HtrA serine peptidase 1 IEP RGD PMID:22595117 RGD:7394756 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379 		JBrowse link
G Serpine1 serpin family E member 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:27046084)		 Ensembl
RGD		 PMID:27046084 GO_REF:0000107 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Slc34a1 solute carrier family 34 member 1 IEP RGD PMID:12369784 RGD:7243151 NCBI chr17:9,218,876...9,233,852
Ensembl chr17:9,218,876...9,233,852 		JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1856877 (PMID:16025116)		 Ensembl
RGD		 PMID:16025116 GO_REF:0000107 NCBI chr19:34,162,337...34,245,786
Ensembl chr19:34,162,341...34,245,749 		JBrowse link
enamel mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amelx amelogenin, X-linked involved_in ISO
IBA		 (PMID:1916828)
GO_REF:0000033
(MGI:6716964|PMID:26403673)
(PMID:21653221)		 RGD
GO_Central		 PMID:1916828 PMID:21653221 PMID:26403673 GO_REF:0000033 MGI:6716964 NCBI chr  X:25,076,362...25,087,660
Ensembl chr  X:25,076,362...25,087,660 		JBrowse link
G Cftr CF transmembrane conductance regulator IMP RGD PMID:31942562 RGD:126928119 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Cnnm4 cyclin and CBS domain divalent metal cation transport mediator 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:24339795)		 Ensembl
RGD		 PMID:24339795 GO_REF:0000107 NCBI chr 9:38,711,726...38,750,942
Ensembl chr 9:38,711,710...38,750,942 		JBrowse link
G Fam20a FAM20A, golgi associated secretory pathway pseudokinase involved_in
acts_upstream_of_or_within		 ISO
IBA		 (PMID:21549343), (PMID:21990045), (PMID:23468644)
MGI:5432376 (PMID:22732358)
GO_REF:0000033		 RGD
GO_Central		 PMID:21549343 PMID:21990045 PMID:22732358 PMID:23468644 GO_REF:0000033 NCBI chr10:94,638,836...94,697,814
Ensembl chr10:94,642,850...94,697,672 		JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:5432377 (PMID:22732358)		 GO_Central
RGD		 PMID:22732358 GO_REF:0000033 NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543 		JBrowse link
G Foxo1 forkhead box O1 IEP RGD PMID:25183529 RGD:10044263 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Itgb6 integrin subunit beta 6 acts_upstream_of_or_within ISO MGI:1926484 (PMID:23264742) RGD PMID:23264742 NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671 		JBrowse link
G Msx2 msh homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1926381 (PMID:10742104)		 Ensembl
RGD		 PMID:10742104 GO_REF:0000107 NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879 		JBrowse link
G Nectin1 nectin cell adhesion molecule 1 acts_upstream_of_or_within ISO MGI:3814719 (PMID:18703497) RGD PMID:18703497 NCBI chr 8:44,101,776...44,164,863
Ensembl chr 8:44,101,776...44,189,787 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha acts_upstream_of_or_within ISO MGI:1857774 (PMID:19320717) RGD PMID:19320717 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Rogdi rogdi atypical leucine zipper acts_upstream_of_or_within ISO (PMID:38172607) RGD PMID:38172607 NCBI chr10:10,567,834...10,572,453
Ensembl chr10:10,567,834...10,572,452 		JBrowse link
G Stim1 stromal interaction molecule 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24621671)		 UniProt
RGD		 PMID:24621671 GO_REF:0000024 NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363 		JBrowse link
G Tbx1 T-box transcription factor 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:2179136 (PMID:19233155)		 UniProt
RGD		 PMID:19233155 GO_REF:0000024 NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380 		JBrowse link
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 acts_upstream_of_or_within ISO MGI:1856973 (PMID:23174213) RGD PMID:23174213 NCBI chr 1:201,127,034...201,138,787
Ensembl chr 1:201,127,034...201,138,742 		JBrowse link
G Wdr72 WD repeat domain 72 acts_upstream_of_or_within ISO MGI:4363147|MGI:5913851 (PMID:25008349), (PMID:26247047) RGD PMID:25008349 PMID:26247047 NCBI chr 8:74,838,338...75,020,938
Ensembl chr 8:74,838,318...75,018,229 		JBrowse link
negative regulation of odontogenesis of dentin-containing tooth term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rspo2 R-spondin 2 acts_upstream_of_or_within ISO MGI:3839444 (PMID:24616052) RGD PMID:24616052 NCBI chr 7:74,096,378...74,239,398
Ensembl chr 7:74,103,090...74,238,933 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B acts_upstream_of_or_within IEP
ISO		 (PMID:14981127) RGD PMID:14981127 PMID:16283633 RGD:1624174 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538 		JBrowse link
positive regulation of dentin-containing tooth bud formation by mesenchymal-epithelial signaling term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir875 microRNA 875 involved_in ISO (PMID:32188878) RGD PMID:32188878 NCBI chr 7:66,861,955...66,862,027
Ensembl chr 7:66,861,955...66,862,027 		JBrowse link
positive regulation of enamel mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amtn amelotin involved_in ISO
IBA
IEA
ISS		 (MGI:5613837|PMID:25407797)
GO_REF:0000033
GO_REF:0000002
GO_REF:0000024		 RGD
GO_Central
InterPro
UniProt		 PMID:25407797 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 MGI:5613837 NCBI chr14:19,648,624...19,661,181
Ensembl chr14:19,648,625...19,661,181 		JBrowse link
G Cftr CF transmembrane conductance regulator involved_in IEA
ISO		 GO_REF:0000107
(MGI:6716964|PMID:26403673)		 Ensembl
RGD		 PMID:26403673 GO_REF:0000107 MGI:6716964 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756 		JBrowse link
G Dspp dentin sialophosphoprotein acts_upstream_of_or_within ISO (PMID:16014627) RGD PMID:16014627 NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672 		JBrowse link
G Enam enamelin involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:3796583 (PMID:24603688)		 GO_Central
RGD		 PMID:24603688 GO_REF:0000033 NCBI chr14:19,556,729...19,581,433
Ensembl chr14:19,556,729...19,581,425 		JBrowse link
G Odaph odontogenesis associated phosphoprotein involved_in ISO
IBA
IEA
ISS		 (PMID:22901946)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:22901946 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr14:16,071,835...16,080,151
Ensembl chr14:16,073,058...16,080,129 		JBrowse link
G Slc4a2 solute carrier family 4 member 2 involved_in ISO (MGI:6716964|PMID:26403673) RGD PMID:26403673 MGI:6716964 NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965 		JBrowse link
positive regulation of odontogenesis of dentin-containing tooth term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csf1 colony stimulating factor 1 acts_upstream_of_or_within ISO MGI:1856333 (PMID:12865350) RGD PMID:12865350 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Ngfr nerve growth factor receptor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857226 (PMID:9268129)		 Ensembl
RGD		 PMID:9268129 GO_REF:0000107 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Prkcb protein kinase C, beta IEP RGD PMID:15763930 RGD:1625521 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536 		JBrowse link
regulation of enamel mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dicer1 dicer 1 ribonuclease III acts_upstream_of_or_within ISO MGI:3589208 (PMID:20102707) RGD PMID:20102707 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Dmp1 dentin matrix acidic phosphoprotein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:16014627)		 Ensembl
RGD		 PMID:16014627 GO_REF:0000107 NCBI chr14:5,528,441...5,542,078
Ensembl chr14:5,528,431...5,539,323 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of ISO MGI:7505608 (PMID:30243146), (PMID:31336344) RGD PMID:30243146 PMID:31336344 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
regulation of odontogenesis of dentin-containing tooth term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apcdd1 APC down-regulated 1 involved_in ISO (MGI:6379934|PMID:26170146) RGD PMID:26170146 MGI:6379934 NCBI chr18:56,385,398...56,416,065
Ensembl chr18:56,385,264...56,416,070 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:88180|MGI:99604 (PMID:9244299)		 Ensembl
RGD		 PMID:9244299 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:88177|MGI:99604 (PMID:9244299)		 Ensembl
RGD		 PMID:9244299 GO_REF:0000107 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Dicer1 dicer 1 ribonuclease III acts_upstream_of_or_within ISO MGI:3589208 (PMID:20102707) RGD PMID:20102707 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965 		JBrowse link
G Dmrt3 doublesex and mab-3 related transcription factor 3 acts_upstream_of_or_within ISO MGI:4420993 (PMID:17803355) RGD PMID:17803355 NCBI chr 1:223,244,340...223,264,254
Ensembl chr 1:223,248,747...223,262,530 		JBrowse link
G Fgf8 fibroblast growth factor 8 acts_upstream_of_or_within ISO MGI:88177|MGI:88180 (PMID:9244299) RGD PMID:9244299 NCBI chr 1:244,584,477...244,590,578
Ensembl chr 1:244,584,652...244,590,359 		JBrowse link
G Ift88 intraflagellar transport 88 acts_upstream_of_or_within ISO MGI:2157527 (PMID:12701101) RGD PMID:12701101 NCBI chr15:31,573,325...31,666,068
Ensembl chr15:31,573,376...31,672,147 		JBrowse link
G Runx2 RUNX family transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2176465 (PMID:14688224)		 Ensembl
RGD		 PMID:14688224 GO_REF:0000107 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Wnt10a Wnt family member 10A acts_upstream_of_or_within ISO (PMID:17286598) RGD PMID:17286598 NCBI chr 9:76,349,931...76,362,400
Ensembl chr 9:76,349,931...76,362,400 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    developmental process 6963
      anatomical structure morphogenesis 2956
        animal organ morphogenesis 1173
          odontogenesis 152
            odontogenesis of dentin-containing tooth 110
              amelogenesis + 32
              dentin extracellular matrix secretion 0
              dentinogenesis + 7
              negative regulation of odontogenesis of dentin-containing tooth 2
              positive regulation of odontogenesis of dentin-containing tooth + 4
              regulation of odontogenesis of dentin-containing tooth + 15
              tooth placode formation 0
Path 2
Term Annotations click to browse term
  biological_process 19692
    developmental process 6963
      anatomical structure development 6486
        anatomical structure morphogenesis 2956
          animal organ morphogenesis 1173
            odontogenesis 152
              odontogenesis of dentin-containing tooth 110
                amelogenesis + 32
                dentin extracellular matrix secretion 0
                dentinogenesis + 7
                negative regulation of odontogenesis of dentin-containing tooth 2
                positive regulation of odontogenesis of dentin-containing tooth + 4
                regulation of odontogenesis of dentin-containing tooth + 15
                tooth placode formation 0
paths to the root