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ONTOLOGY REPORT - ANNOTATIONS


Term:amelogenesis
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Accession:GO:0097186 term browser browse the term
Definition:The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage.
Synonyms:exact_synonym: enamel development



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amelogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amelx amelogenin, X-linked involved_in ISO (MGI:6716964|PMID:26403673) RGD PMID:26403673 MGI:6716964 NCBI chr  X:25,076,362...25,087,660
Ensembl chr  X:25,076,362...25,087,660
JBrowse link
G Ascl5 achaete-scute family bHLH transcription factor 5 involved_in ISO (MGI:6305509|PMID:30504223), (MGI:7280983|PMID:34812512) RGD PMID:30504223 PMID:34812512 MGI:6305509 MGI:7280983 NCBI chr13:47,491,799...47,493,269
Ensembl chr13:47,492,026...47,492,592
JBrowse link
G Atf2 activating transcription factor 2 IDA RGD PMID:15218628 RGD:10053659 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Cftr CF transmembrane conductance regulator involved_in IEA
ISO
GO_REF:0000107
(MGI:6716964|PMID:26403673)
Ensembl
RGD
PMID:26403673 GO_REF:0000107 MGI:6716964 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Csf3r colony stimulating factor 3 receptor IEP RGD PMID:10206335 RGD:5134351 NCBI chr 5:138,298,605...138,318,224
Ensembl chr 5:138,301,506...138,317,881
JBrowse link
G Dspp dentin sialophosphoprotein acts_upstream_of_or_within ISO MGI:2653208 (MGI:5912858|PMID:25027178) RGD PMID:25027178 MGI:5912858 NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672
JBrowse link
G Enam enamelin acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:3055582|MGI:3055586|MGI:3055587|MGI:3796583 (MGI:3530197|PMID:15649948), (MGI:3796449|PMID:18252720), (MGI:5634640|PMID:22813216), (MGI:5647983|PMID:24603688)
GO_REF:0000033
RGD
GO_Central
PMID:15649948 PMID:18252720 PMID:22813216 PMID:24603688 GO_REF:0000033 MGI:3530197 MGI:3796449 MGI:5634640 MGI:5647983 NCBI chr14:19,556,729...19,581,433
Ensembl chr14:19,556,729...19,581,425
JBrowse link
G Klk4 kallikrein-related peptidase 4 involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:15235027)
MGI:4355346 (MGI:4354666|PMID:19578120), (MGI:5008529|PMID:21454549), (MGI:5502300|PMID:22243248)
GO_REF:0000033
RGD
GO_Central
PMID:15235027 PMID:19578120 PMID:21454549 PMID:22243248 GO_REF:0000033 MGI:4354666 MGI:5008529 MGI:5502300 NCBI chr 1:94,344,195...94,349,425
Ensembl chr 1:94,344,195...94,349,424
JBrowse link
G Klk5 kallikrein related-peptidase 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:94,296,574...94,304,768
Ensembl chr 1:94,296,168...94,304,666
JBrowse link
G Mmp20 matrix metallopeptidase 20 acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:2447874 (MGI:3522683|PMID:15557396), (MGI:5008529|PMID:21454549), (MGI:5502300|PMID:22243248)
GO_REF:0000033
RGD
GO_Central
PMID:15557396 PMID:21454549 PMID:22243248 GO_REF:0000033 MGI:3522683 MGI:5008529 MGI:5502300 NCBI chr 8:4,789,415...4,830,035
Ensembl chr 8:4,789,415...4,830,035
JBrowse link
G Perp p53 apoptosis effector related to PMP22 acts_upstream_of_or_within ISO MGI:2683069 (MGI:5317035|PMID:21285247) RGD PMID:21285247 MGI:5317035 NCBI chr 1:13,542,067...13,554,514
Ensembl chr 1:13,542,067...13,554,511
JBrowse link
G Relt RELT, TNF receptor involved_in ISO
IBA
(PMID:30506946)
(MGI:6368096|PMID:30506946)
GO_REF:0000033
RGD
GO_Central
PMID:30506946 GO_REF:0000033 MGI:6368096 NCBI chr 1:155,206,976...155,224,609
Ensembl chr 1:155,206,976...155,214,196
JBrowse link
G Slc24a4 solute carrier family 24 member 4 involved_in ISO (MGI:5520028|PMID:23375655), (MGI:6716966|PMID:27752731) RGD PMID:23375655 PMID:27752731 MGI:5520028 MGI:6716966 NCBI chr 6:121,279,590...121,419,811
Ensembl chr 6:121,280,031...121,414,949
JBrowse link
G Slc4a2 solute carrier family 4 member 2 involved_in ISO (MGI:6716964|PMID:26403673) RGD PMID:26403673 MGI:6716964 NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965
JBrowse link
enamel mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amelx amelogenin, X-linked involved_in ISO
IBA
IEA
(PMID:1916828)
GO_REF:0000033
GO_REF:0000118
(MGI:6716964|PMID:26403673)
(PMID:21653221)
RGD
GO_Central
TreeGrafter
PMID:1916828 PMID:21653221 PMID:26403673 GO_REF:0000033 GO_REF:0000118 MGI:6716964 NCBI chr  X:25,076,362...25,087,660
Ensembl chr  X:25,076,362...25,087,660
JBrowse link
G Cftr CF transmembrane conductance regulator IMP RGD PMID:31942562 RGD:126928119 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Cnnm4 cyclin and CBS domain divalent metal cation transport mediator 4 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5559016|PMID:24339795)
GO_REF:0000107
RGD
Ensembl
PMID:24339795 GO_REF:0000107 MGI:5559016 NCBI chr 9:38,711,726...38,750,942
Ensembl chr 9:38,711,710...38,750,942
JBrowse link
G Fam20a FAM20A, golgi associated secretory pathway pseudokinase involved_in
acts_upstream_of_or_within
ISO
IBA
(PMID:21549343), (PMID:21990045), (PMID:23468644)
GO_REF:0000033
MGI:5432376 (MGI:5432245|PMID:22732358)
RGD
GO_Central
PMID:21549343 PMID:21990045 PMID:22732358 PMID:23468644 GO_REF:0000033 MGI:5432245 NCBI chr10:94,638,836...94,697,814
Ensembl chr10:94,642,850...94,697,672
JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:5432377 (MGI:5432245|PMID:22732358)
GO_REF:0000033
RGD
GO_Central
PMID:22732358 GO_REF:0000033 MGI:5432245 NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543
JBrowse link
G Foxo1 forkhead box O1 IEP RGD PMID:25183529 RGD:10044263 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
JBrowse link
G Itgb6 integrin subunit beta 6 acts_upstream_of_or_within ISO MGI:1926484 (MGI:5507902|PMID:23264742) RGD PMID:23264742 MGI:5507902 NCBI chr 3:45,046,295...45,170,532
Ensembl chr 3:45,048,044...45,121,671
JBrowse link
G Msx2 msh homeobox 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:1926381 (MGI:1355063|PMID:10742104)
Ensembl
RGD
PMID:10742104 GO_REF:0000107 MGI:1355063 NCBI chr17:11,097,214...11,102,879
Ensembl chr17:11,097,103...11,102,879
JBrowse link
G Nectin1 nectin cell adhesion molecule 1 acts_upstream_of_or_within ISO MGI:3814719 (MGI:3814115|PMID:18703497) RGD PMID:18703497 MGI:3814115 NCBI chr 8:44,101,776...44,164,863
Ensembl chr 8:44,101,776...44,189,787
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha acts_upstream_of_or_within ISO MGI:1857774 (MGI:3843118|PMID:19320717) RGD PMID:19320717 MGI:3843118 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Stim1 stromal interaction molecule 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:24621671)
UniProt
RGD
PMID:24621671 GO_REF:0000024 NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363
JBrowse link
G Tbx1 T-box transcription factor 1 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:2179136 (MGI:3848106|PMID:19233155)
UniProt
RGD
PMID:19233155 GO_REF:0000024 MGI:3848106 NCBI chr11:82,409,275...82,419,058
Ensembl chr11:82,409,275...82,418,380
JBrowse link
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 acts_upstream_of_or_within ISO MGI:1856973 (MGI:5469811|PMID:23174213) RGD PMID:23174213 MGI:5469811 NCBI chr 1:201,127,034...201,138,787
Ensembl chr 1:201,127,034...201,138,742
JBrowse link
G Wdr72 WD repeat domain 72 acts_upstream_of_or_within ISO MGI:4363147|MGI:5913851 (MGI:5605934|PMID:25008349), (MGI:5906533|PMID:26247047) RGD PMID:25008349 PMID:26247047 MGI:5605934 MGI:5906533 NCBI chr 8:74,838,338...75,020,938
Ensembl chr 8:74,838,318...75,018,229
JBrowse link
positive regulation of enamel mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amtn amelotin involved_in ISO
IBA
IEA
ISS
(MGI:5613837|PMID:25407797)
GO_REF:0000033
GO_REF:0000118
GO_REF:0000002
GO_REF:0000024
RGD
GO_Central
TreeGrafter
InterPro
UniProt
PMID:25407797 GO_REF:0000002 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 MGI:5613837 NCBI chr14:19,648,624...19,661,181
Ensembl chr14:19,648,625...19,661,181
JBrowse link
G Cftr CF transmembrane conductance regulator involved_in IEA
ISO
GO_REF:0000107
(MGI:6716964|PMID:26403673)
Ensembl
RGD
PMID:26403673 GO_REF:0000107 MGI:6716964 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Dspp dentin sialophosphoprotein acts_upstream_of_or_within ISO (MGI:3603472|PMID:16014627) RGD PMID:16014627 MGI:3603472 NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672
JBrowse link
G Enam enamelin acts_upstream_of_or_within
involved_in
ISO
IBA
MGI:3796583 (MGI:5647983|PMID:24603688)
GO_REF:0000033
RGD
GO_Central
PMID:24603688 GO_REF:0000033 MGI:5647983 NCBI chr14:19,556,729...19,581,433
Ensembl chr14:19,556,729...19,581,425
JBrowse link
G Odaph odontogenesis associated phosphoprotein involved_in ISO
IBA
IEA
ISS
(PMID:22901946)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024
RGD
GO_Central
Ensembl
UniProt
PMID:22901946 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr14:16,071,835...16,080,151
Ensembl chr14:16,073,058...16,080,129
JBrowse link
G Slc4a2 solute carrier family 4 member 2 involved_in ISO (MGI:6716964|PMID:26403673) RGD PMID:26403673 MGI:6716964 NCBI chr 4:10,736,419...10,754,407
Ensembl chr 4:10,736,425...10,752,965
JBrowse link
regulation of enamel mineralization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dicer1 dicer 1 ribonuclease III acts_upstream_of_or_within ISO MGI:3589208 (MGI:4453947|PMID:20102707) RGD PMID:20102707 MGI:4453947 NCBI chr 6:123,627,529...123,692,278
Ensembl chr 6:123,631,250...123,693,965
JBrowse link
G Dmp1 dentin matrix acidic phosphoprotein 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3603472|PMID:16014627)
GO_REF:0000107
RGD
Ensembl
PMID:16014627 GO_REF:0000107 MGI:3603472 NCBI chr14:5,528,441...5,542,078
Ensembl chr14:5,528,431...5,539,323
JBrowse link
G Tgfb1 transforming growth factor, beta 1 acts_upstream_of ISO MGI:7505608 (MGI:6443509|PMID:31336344), (MGI:6690584|PMID:30243146) RGD PMID:30243146 PMID:31336344 MGI:6443509 MGI:6690584 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20350
    developmental process 7023
      anatomical structure formation involved in morphogenesis 1373
        amelogenesis 31
          enamel mineralization + 22
Path 2
Term Annotations click to browse term
  biological_process 20350
    developmental process 7023
      anatomical structure development 6530
        animal organ development 3668
          animal organ morphogenesis 1177
            odontogenesis 150
              odontogenesis of dentin-containing tooth 110
                amelogenesis 31
                  enamel mineralization + 22
paths to the root