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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:myricetin
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Accession:CHEBI:18152 term browser browse the term
Definition:A hexahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 3', 4', 5, 5' and 7. It has been isolated from the leaves of Myrica rubra and other plants.
Synonyms:exact_synonym: 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one
 related_synonym: 3,3',4',5,5',7-Hexahydroxyflavone;   Cannabiscetin;   Formula=C15H10O8;   InChI=1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H;   InChIKey=IKMDFBPHZNJCSN-UHFFFAOYSA-N;   Myricetol;   SMILES=Oc1cc(O)c2c(c1)oc(-c1cc(O)c(O)c(O)c1)c(O)c2=O
 alt_id: CHEBI:14636;   CHEBI:44341;   CHEBI:7053
 xref: CAS:529-44-2;   DrugBank:DB02375;   HMDB:HMDB0002755;   KEGG:C10107;   KNApSAcK:C00001071;   LINCS:LSM-2957;   LIPID_MAPS_instance:LMPK12110001
 xref_mesh: MESH:C040015
 xref: MetaCyc:MYRICETIN;   PDBeChem:MYC;   PMID:19407970;   PMID:19778600;   PMID:22482362;   PMID:23099505;   PMID:23232835;   PMID:23265454;   PMID:23736695;   Reaxys:332331;   Wikipedia:Myricetin
 cyclic_relationship: is_conjugate_acid_of CHEBI:58395



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myricetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A increases activity
increases expression
multiple interactions
ISO myricetin results in increased activity of ABCB1 protein
myricetin results in increased expression of ABCB1 protein
myricetin inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]
CTD PMID:34217736 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 decreases activity
multiple interactions
ISO myricetin results in decreased activity of ABCC1 protein
myricetin inhibits the reaction [ABCC1 protein affects the export of and results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC1 protein affects the export of Vincristine]; myricetin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC1 protein results in increased uptake of Leukotriene C4]
CTD PMID:11306701 PMID:15670588 PMID:15896345 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601
JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 multiple interactions
decreases activity
ISO myricetin inhibits the reaction [ABCC2 protein affects the export of and results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC2 protein affects the export of Vincristine]; myricetin inhibits the reaction [ABCC2 protein results in decreased susceptibility to Vincristine]
myricetin results in decreased activity of ABCC2 protein
CTD PMID:15670588 PMID:15896345 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Afp alpha fetoprotein affects binding ISO myricetin binds to AFP protein CTD PMID:23013281 PMID:25349334 NCBI chr 5:90,638,573...90,656,766
Ensembl chr 5:90,638,596...90,656,766
JBrowse link
G Alb albumin multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of ALB protein] CTD PMID:24923654 PMID:25240712 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461
JBrowse link
G Arhgdib Rho, GDP dissociation inhibitor beta increases cleavage ISO myricetin results in increased cleavage of ARHGDIB protein CTD PMID:15748703 NCBI chr 6:136,900,653...136,918,895
Ensembl chr 6:136,900,653...136,918,897
JBrowse link
G Atr ataxia telangiectasia and Rad3 related multiple interactions ISO myricetin affects the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of ATR mRNA] CTD PMID:32342131 NCBI chr 9:95,739,655...95,834,813
Ensembl chr 9:95,739,650...95,833,834
JBrowse link
G Bax BCL2-associated X protein decreases expression
multiple interactions
ISO myricetin results in decreased expression of BAX protein
Tetradecanoylphorbol Acetate inhibits the reaction [myricetin results in decreased expression of BAX protein]
CTD PMID:15748703 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression
multiple interactions
ISO myricetin results in decreased expression of BCL2 protein
Tetradecanoylphorbol Acetate inhibits the reaction [myricetin results in decreased expression of BCL2 protein]
CTD PMID:15748703 PMID:29698783 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage
ISO myricetin results in increased activity of CASP3 protein
myricetin results in increased cleavage of CASP3 protein
CTD PMID:15748703 PMID:19397994 PMID:29698783 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp8 caspase 8 decreases expression ISO myricetin results in decreased expression of CASP8 protein CTD PMID:29698783 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Casp9 caspase 9 increases activity
increases cleavage
ISO myricetin results in increased activity of CASP9 protein
myricetin results in increased cleavage of CASP9 protein
CTD PMID:15748703 PMID:29698783 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cat catalase multiple interactions ISO myricetin inhibits the reaction [Rotenone results in increased activity of CAT protein]
myricetin inhibits the reaction [Ethanol results in decreased activity of CAT protein]
CTD PMID:15904944 PMID:35156864 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO myricetin results in decreased expression of CCNB1 mRNA; myricetin results in decreased expression of CCNB1 protein CTD PMID:19397994 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression ISO myricetin results in increased expression of CDKN1A mRNA; myricetin results in increased expression of CDKN1A protein CTD PMID:19397994 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cdkn2c cyclin dependent kinase inhibitor 2C increases expression ISO myricetin results in increased expression of CDKN2C mRNA CTD PMID:18331776 NCBI chr 4:109,518,073...109,523,953
Ensembl chr 4:109,518,073...109,524,386
JBrowse link
G Cfl1 cofilin 1, non-muscle increases expression ISO myricetin results in increased expression of CFL1 protein CTD PMID:29698783 NCBI chr19:5,540,483...5,544,059
Ensembl chr19:5,540,483...5,545,229
JBrowse link
G Cldn1 claudin 1 multiple interactions ISO myricetin inhibits the reaction [Indomethacin results in decreased expression of CLDN1 mRNA]; myricetin inhibits the reaction [Indomethacin results in decreased expression of CLDN1 protein] CTD PMID:33276066 NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591
JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [myricetin co-treated with COMT protein] results in decreased activity of DNMT1 protein CTD PMID:16037419 NCBI chr16:18,225,632...18,247,006
Ensembl chr16:18,225,636...18,245,602
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B increases expression ISO myricetin results in increased expression of COX5B protein CTD PMID:29698783 NCBI chr 1:36,730,568...36,732,469
Ensembl chr 1:36,730,530...36,732,762
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression
multiple interactions
ISO myricetin results in decreased expression of CTNNB1 protein
[myricetin results in increased activity of SIRT1 protein] which results in decreased expression of CTNNB1 protein
CTD PMID:22245592 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573
JBrowse link
G Cycs cytochrome c, somatic affects localization
multiple interactions
ISO myricetin affects the localization of CYCS protein
Tetradecanoylphorbol Acetate inhibits the reaction [myricetin affects the localization of CYCS protein]
CTD PMID:15748703 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP myricetin promotes the reaction [Cyclic AMP results in increased expression of CYP11A1 mRNA] CTD PMID:28668616 NCBI chr 9:57,905,307...57,934,314
Ensembl chr 9:57,913,694...57,934,306
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
increases expression
multiple interactions
ISO
EXP
myricetin results in decreased activity of CYP1A1 protein
myricetin results in increased expression of CYP1A1 mRNA
myricetin inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]
CTD PMID:16271822 PMID:20930378 PMID:21482471 PMID:29584932 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO myricetin results in decreased activity of CYP1A2 protein CTD PMID:29753067 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO myricetin results in decreased activity of CYP1B1 protein CTD PMID:16271822 PMID:21482471 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 decreases activity ISO myricetin results in decreased activity of CYP2A6 protein CTD PMID:29753067 NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 decreases activity ISO myricetin results in decreased activity of CYP2C19 protein CTD PMID:29753067 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 decreases activity ISO myricetin results in decreased activity of CYP2C9 protein CTD PMID:29753067 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 decreases activity ISO myricetin results in decreased activity of CYP2D6 protein CTD PMID:29753067 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO myricetin results in decreased activity of CYP2E1 protein CTD PMID:29753067 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions
decreases activity
ISO [myricetin co-treated with COMT protein] results in decreased activity of DNMT1 protein
myricetin results in decreased activity of DNMT1 protein
CTD PMID:16037419 NCBI chr 9:20,818,501...20,871,084
Ensembl chr 9:20,818,505...20,871,184
JBrowse link
G Egf epidermal growth factor multiple interactions EXP myricetin inhibits the reaction [EGF protein results in increased expression of FOS mRNA]; myricetin inhibits the reaction [EGF protein results in increased expression of STAT3 mRNA]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of JAK1 protein]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK9 protein]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KA1 protein]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]; myricetin promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:17693661 PMID:18995957 NCBI chr 3:129,471,223...129,548,971
Ensembl chr 3:129,471,214...129,548,965
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
decreases phosphorylation
EXP myricetin promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein]
myricetin results in decreased phosphorylation of EGFR protein
CTD PMID:18995957 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 decreases expression
multiple interactions
ISO myricetin results in decreased expression of EGLN1 protein
[myricetin results in increased activity of SIRT1 protein] which results in decreased expression of EGLN1 protein
CTD PMID:22245592 NCBI chr 8:125,635,325...125,676,063
Ensembl chr 8:125,635,326...125,676,063
JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO myricetin promotes the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]] CTD PMID:20153296 NCBI chr15:81,470,329...81,536,273
Ensembl chr15:81,469,552...81,536,278
JBrowse link
G Fbp1 fructose bisphosphatase 1 decreases expression ISO myricetin results in decreased expression of FBP1 mRNA CTD PMID:18331776 NCBI chr13:63,012,567...63,036,112
Ensembl chr13:63,012,567...63,036,096
JBrowse link
G Fdx1 ferredoxin 1 multiple interactions EXP myricetin promotes the reaction [Cyclic AMP results in increased expression of FDX1 mRNA] CTD PMID:28668616 NCBI chr 9:51,854,323...51,874,902
Ensembl chr 9:51,854,606...51,874,856
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of FN1 protein] CTD PMID:25240712 NCBI chr 1:71,624,632...71,692,439
Ensembl chr 1:71,624,679...71,692,359
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions EXP myricetin inhibits the reaction [EGF protein results in increased expression of FOS mRNA]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA] CTD PMID:17693661 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein] CTD PMID:24923654 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800
JBrowse link
G Gm20348 predicted gene, 20348 increases expression ISO myricetin results in increased expression of TP53I3 mRNA; myricetin results in increased expression of TP53I3 protein CTD PMID:19397994 NCBI chr12:4,860,475...4,867,155
Ensembl chr12:4,860,494...4,867,142
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions ISO myricetin inhibits the reaction [Ethanol results in increased activity of GPT protein] CTD PMID:35156864 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Gsr glutathione reductase multiple interactions ISO myricetin inhibits the reaction [Ethanol results in decreased activity of GSR protein] CTD PMID:35156864 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO myricetin inhibits the reaction [Doxorubicin results in increased expression of H2AX protein] CTD PMID:32107588 NCBI chr 9:44,246,012...44,247,374
Ensembl chr 9:44,245,991...44,247,374
JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO myricetin affects the reaction [Sodium Chloride results in increased expression of HBEGF mRNA] CTD PMID:26800359 NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858
JBrowse link
G Hgf hepatocyte growth factor multiple interactions ISO myricetin inhibits the reaction [HGF protein results in increased phosphorylation of MET protein] CTD PMID:19244381 NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit increases expression
decreases activity
multiple interactions
ISO myricetin results in increased expression of HIF1A protein
myricetin results in decreased activity of HIF1A protein
[myricetin results in increased activity of SIRT1 protein] which results in increased expression of HIF1A protein; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HIF1A mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HIF1A protein]]; myricetin inhibits the reaction [Formaldehyde results in increased expression of HIF1A mRNA]; myricetin inhibits the reaction [Formaldehyde results in increased expression of HIF1A protein]; myricetin promotes the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]
CTD PMID:19958256 PMID:20153296 PMID:22245592 PMID:36116563 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Hk2 hexokinase 2 multiple interactions ISO Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HK2 mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HK2 protein]]; myricetin inhibits the reaction [Formaldehyde results in increased expression of HK2 mRNA]; myricetin inhibits the reaction [Formaldehyde results in increased expression of HK2 protein] CTD PMID:36116563 NCBI chr 6:82,702,004...82,751,437
Ensembl chr 6:82,702,006...82,751,435
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased activity of HMGCR protein] CTD PMID:25240712 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO myricetin results in increased expression of HMOX1 protein CTD PMID:16799064 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hras Harvey rat sarcoma virus oncogene decreases activity EXP myricetin results in decreased activity of HRAS protein CTD PMID:17693661 NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918
JBrowse link
G Il6 interleukin 6 multiple interactions ISO myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]
myricetin inhibits the reaction [Ethanol results in increased expression of IL6 protein]
CTD PMID:18958421 PMID:35156864 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Ins1 insulin I multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of INS1 protein] CTD PMID:24923654 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of IRS1 protein] CTD PMID:24923654 NCBI chr 1:82,210,826...82,269,160
Ensembl chr 1:82,210,822...82,269,137
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of IRS2 protein] CTD PMID:24923654 NCBI chr 8:11,034,681...11,058,929
Ensembl chr 8:11,034,681...11,058,458
JBrowse link
G Jak1 Janus kinase 1 affects binding
multiple interactions
ISO
EXP
myricetin binds to JAK1 protein
myricetin inhibits the reaction [EGF protein results in increased phosphorylation of JAK1 protein]
CTD PMID:18995957 NCBI chr 4:101,009,171...101,122,493
Ensembl chr 4:101,009,564...101,122,479
JBrowse link
G Lcat lecithin cholesterol acyltransferase multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of LCAT protein] CTD PMID:25240712 NCBI chr 8:106,666,183...106,670,034
Ensembl chr 8:106,666,183...106,670,014
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions ISO Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of LDHA mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of LDHA protein]]; myricetin inhibits the reaction [Formaldehyde results in increased expression of LDHA mRNA]; myricetin inhibits the reaction [Formaldehyde results in increased expression of LDHA protein] CTD PMID:36116563 NCBI chr 7:46,491,698...46,505,051
Ensembl chr 7:46,490,899...46,505,051
JBrowse link
G Lpl lipoprotein lipase multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of LPL protein] CTD PMID:25240712 NCBI chr 8:69,333,207...69,359,584
Ensembl chr 8:69,333,143...69,360,100
JBrowse link
G Ltf lactotransferrin increases expression ISO myricetin results in increased expression of LTF protein CTD PMID:24487097 NCBI chr 9:110,848,360...110,871,834
Ensembl chr 9:110,848,339...110,871,835
JBrowse link
G Ltn1 listerin E3 ubiquitin protein ligase 1 decreases expression ISO myricetin results in decreased expression of LTN1 protein CTD PMID:29698783 NCBI chr16:87,173,539...87,229,504
Ensembl chr16:87,173,539...87,229,500
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 multiple interactions EXP myricetin binds to and results in decreased activity of MAP2K1 protein; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAP2K1 protein] CTD PMID:17693661 NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913
JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 decreases phosphorylation EXP Myricetin decreases phosphorylation of Map3k7 protein in the heart RGD PMID:31885808 RGD:155791644 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
decreases activity
EXP myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]
myricetin results in decreased activity of MAPK1 protein
CTD PMID:17693661 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions EXP myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein] CTD PMID:17693661 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions EXP myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK9 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein] CTD PMID:17693661 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248
JBrowse link
G Met met proto-oncogene multiple interactions ISO myricetin inhibits the reaction [HGF protein results in increased phosphorylation of MET protein] CTD PMID:19244381 NCBI chr 6:17,463,351...17,573,979
Ensembl chr 6:17,463,799...17,573,979
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein] CTD PMID:19804834 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Myc myelocytomatosis oncogene decreases expression
multiple interactions
ISO myricetin results in decreased expression of MYC protein
[myricetin results in increased activity of SIRT1 protein] which results in decreased expression of MYC protein
CTD PMID:22245592 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 increases expression ISO myricetin results in increased expression of NFE2L2 protein CTD PMID:16799064 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 increases expression ISO myricetin results in increased expression of NME1 protein CTD PMID:29698783 NCBI chr11:93,849,751...93,859,341
Ensembl chr11:93,847,805...93,859,347
JBrowse link
G Ocln occludin multiple interactions ISO myricetin inhibits the reaction [Indomethacin results in decreased expression of OCLN mRNA]; myricetin inhibits the reaction [Indomethacin results in decreased expression of OCLN protein] CTD PMID:33276066 NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
JBrowse link
G Parg poly (ADP-ribose) glycohydrolase decreases activity ISO myricetin results in decreased activity of PARG protein CTD PMID:19840838 NCBI chr14:31,923,900...32,020,671
Ensembl chr14:31,923,906...32,019,507
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage
decreases activity
ISO myricetin results in increased cleavage of PARP1 protein
myricetin results in decreased activity of PARP1 protein
CTD PMID:15748703 PMID:17884996 PMID:29698783 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pik3c2b phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta decreases expression ISO myricetin results in decreased expression of PIK3C2B protein CTD PMID:29698783 NCBI chr 1:132,973,410...133,036,429
Ensembl chr 1:132,973,405...133,036,425
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of PPARA protein] CTD PMID:25240712 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Psca prostate stem cell antigen decreases expression ISO myricetin results in decreased expression of PSCA mRNA CTD PMID:18331776 NCBI chr15:74,586,688...74,588,914
Ensembl chr15:74,586,688...74,588,918
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO
EXP
myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
CTD PMID:17944529 PMID:19804834 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of and results in increased activity of RELA protein] CTD PMID:18958421 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Rps12 ribosomal protein S12 decreases expression ISO myricetin results in decreased expression of RPS12 protein CTD PMID:29698783 NCBI chr10:23,661,042...23,664,297
Ensembl chr10:23,661,081...23,663,173
JBrowse link
G Rps6ka1 ribosomal protein S6 kinase polypeptide 1 multiple interactions EXP myricetin inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KA1 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KA1 protein] CTD PMID:17693661 NCBI chr 4:133,574,601...133,615,466
Ensembl chr 4:133,574,601...133,615,108
JBrowse link
G Rps6kb2 ribosomal protein S6 kinase, polypeptide 2 increases expression ISO myricetin results in increased expression of RPS6KB2 protein CTD PMID:29698783 NCBI chr19:4,206,791...4,213,382
Ensembl chr19:4,203,990...4,213,353
JBrowse link
G Sirt1 sirtuin 1 increases activity
increases expression
multiple interactions
ISO myricetin results in increased activity of SIRT1 protein
myricetin results in increased expression of SIRT1 protein
[myricetin results in increased activity of SIRT1 protein] which results in decreased expression of CTNNB1 protein; [myricetin results in increased activity of SIRT1 protein] which results in decreased expression of EGLN1 protein; [myricetin results in increased activity of SIRT1 protein] which results in decreased expression of MYC protein; [myricetin results in increased activity of SIRT1 protein] which results in increased expression of HIF1A protein
CTD PMID:22245592 NCBI chr10:63,154,784...63,174,814
Ensembl chr10:63,154,784...63,217,483
JBrowse link
G Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 multiple interactions
decreases activity
ISO Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 protein]]; myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 mRNA]; myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 protein]; myricetin inhibits the reaction [SLC2A1 protein affects the transport of Glucose]
myricetin results in decreased activity of SLC2A1 protein
CTD PMID:14642735 PMID:36116563 NCBI chr 4:118,966,001...118,994,527
Ensembl chr 4:118,965,908...118,995,180
JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of SLC2A2 protein] CTD PMID:24923654 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508
JBrowse link
G Src Rous sarcoma oncogene multiple interactions ISO myricetin inhibits the reaction [Indomethacin results in increased phosphorylation of SRC protein] CTD PMID:33276066 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF1 protein] CTD PMID:25240712 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407
JBrowse link
G Srebf2 sterol regulatory element binding factor 2 multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF2 protein] CTD PMID:25240712 NCBI chr15:82,031,455...82,089,580
Ensembl chr15:82,031,382...82,089,580
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions EXP myricetin promotes the reaction [Cyclic AMP results in increased expression of STAR mRNA] CTD PMID:28668616 NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions EXP myricetin inhibits the reaction [EGF protein results in increased expression of STAT3 mRNA]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein] CTD PMID:18995957 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Stk38l serine/threonine kinase 38 like decreases expression ISO myricetin results in decreased expression of STK38L protein CTD PMID:29698783 NCBI chr 6:146,626,428...146,680,312
Ensembl chr 6:146,626,493...146,680,310
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of TGFB1 protein] CTD PMID:25240712 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO myricetin inhibits the reaction [Indomethacin results in decreased expression of TJP1 mRNA]; myricetin inhibits the reaction [Indomethacin results in decreased expression of TJP1 protein] CTD PMID:33276066 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]
myricetin inhibits the reaction [Ethanol results in increased expression of TNF protein]
CTD PMID:18958421 PMID:35156864 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Top2a topoisomerase (DNA) II alpha decreases activity ISO myricetin results in decreased activity of TOP2A protein CTD PMID:16536579 NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015
JBrowse link
G Trp53 transformation related protein 53 increases expression
multiple interactions
ISO myricetin analog results in increased expression of TP53 mRNA; myricetin analog results in increased expression of TP53 protein; myricetin results in increased expression of TP53 protein
myricetin affects the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of TP53 mRNA]
CTD PMID:32220605 PMID:32342131 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Trp63 transformation related protein 63 increases expression ISO myricetin results in increased expression of TP63 protein CTD PMID:19397994 NCBI chr16:25,502,513...25,710,842
Ensembl chr16:25,502,513...25,710,852
JBrowse link
G Trp73 transformation related protein 73 increases expression ISO myricetin results in increased expression of TP73 protein CTD PMID:19397994 NCBI chr 4:154,140,706...154,224,332
Ensembl chr 4:154,140,706...154,224,665
JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases activity
multiple interactions
ISO myricetin results in decreased activity of TXNRD1 protein modified form
[Xanthine co-treated with XDH protein] promotes the reaction [myricetin results in decreased activity of TXNRD1 protein modified form]; Nitrogen inhibits the reaction [myricetin results in decreased activity of TXNRD1 protein modified form]
CTD PMID:16618767 NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 decreases activity ISO myricetin results in decreased activity of UGT1A1 protein CTD PMID:35063619 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
JBrowse link
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 decreases activity ISO myricetin results in decreased activity of UGT1A10 protein CTD PMID:35063619 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 decreases activity ISO myricetin results in decreased activity of UGT1A3 protein CTD PMID:35063619 NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719
JBrowse link
G Ugt1a6b UDP glucuronosyltransferase 1 family, polypeptide A6B decreases activity ISO myricetin results in decreased activity of UGT1A6 protein CTD PMID:35063619 NCBI chr 1:88,030,979...88,146,720
Ensembl chr 1:88,030,974...88,146,725
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 decreases activity ISO myricetin results in decreased activity of UGT1A9 protein CTD PMID:35063619 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719
JBrowse link
G Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B34 decreases activity ISO myricetin results in decreased activity of UGT2B7 protein CTD PMID:35063619 NCBI chr 5:87,037,613...87,054,805
Ensembl chr 5:87,037,626...87,054,796
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of VEGFA protein]
myricetin inhibits the reaction [cobaltous chloride results in increased expression of VEGFA mRNA]; myricetin promotes the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]
CTD PMID:20153296 PMID:25240712 PMID:26800359 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions ISO [Xanthine co-treated with XDH protein] promotes the reaction [myricetin results in decreased activity of TXNRD1 protein modified form]; myricetin inhibits the reaction [Ethanol results in increased activity of XDH protein] CTD PMID:16618767 PMID:35156864 NCBI chr17:74,190,890...74,257,191
Ensembl chr17:74,190,890...74,257,191
JBrowse link
(+)-dihydromyricetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK1 protein] CTD PMID:21871475 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK3 protein] CTD PMID:21871475 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide multiple interactions ISO ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK1 protein]; ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK3 protein]; ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PDGFRB protein]; ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PLCG1 protein] CTD PMID:21871475 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178
JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide multiple interactions ISO ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PDGFRB protein] CTD PMID:21871475 NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133
JBrowse link
G Plcg1 phospholipase C, gamma 1 multiple interactions ISO ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PLCG1 protein] CTD PMID:21871475 NCBI chr 2:160,573,230...160,617,680
Ensembl chr 2:160,573,220...160,617,680
JBrowse link
G Sphk1 sphingosine kinase 1 decreases expression
decreases activity
ISO ampelopsin results in decreased expression of SPHK1 protein
ampelopsin results in decreased activity of SPHK1 protein
CTD PMID:22251058 NCBI chr11:116,421,662...116,427,502
Ensembl chr11:116,421,751...116,427,501
JBrowse link
myricitrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions EXP myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:25656916 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
JBrowse link
G Alpl alkaline phosphatase, liver/bone/kidney multiple interactions EXP
ISO
myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ALPL mRNA] CTD PMID:25130202 NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695
JBrowse link
G Apoe apolipoprotein E multiple interactions EXP myricitrin inhibits the reaction [APOE gene mutant form results in decreased activity of CAT protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased activity of CASP3 protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CCL2 protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CRP protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of ICAM1 protein] CTD PMID:23639522 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein] CTD PMID:23639522 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:23639522 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bglap bone gamma carboxyglutamate protein multiple interactions EXP
ISO
myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BGLAP mRNA] CTD PMID:25130202 NCBI chr 3:88,290,802...88,291,773
Ensembl chr 3:88,290,808...88,291,771
JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP
myricitrin inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]
myricitrin inhibits the reaction [APOE gene mutant form results in increased activity of CASP3 protein]
CTD PMID:23639522 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Cat catalase multiple interactions ISO
EXP
myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein]
myricitrin inhibits the reaction [APOE gene mutant form results in decreased activity of CAT protein]
CTD PMID:23639522 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions EXP myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CCL2 protein] CTD PMID:23639522 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Col1a1 collagen, type I, alpha 1 multiple interactions EXP
ISO
myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of COL1A1 mRNA] CTD PMID:25130202 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G Crp C-reactive protein, pentraxin-related multiple interactions EXP myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CRP protein] CTD PMID:23639522 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions EXP myricitrin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein] CTD PMID:25656916 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions EXP myricitrin inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein] CTD PMID:25656916 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of GPX1 protein] CTD PMID:23639522 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions EXP myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of ICAM1 protein] CTD PMID:23639522 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of IL6 protein] CTD PMID:25130202 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein] CTD PMID:23639522 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein] CTD PMID:23639522 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:23639522 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of NOS3 protein] CTD PMID:23639522 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP myricitrin promotes the reaction [Carbon Tetrachloride results in increased expression of PCNA protein] CTD PMID:25656916 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of PPARG mRNA] CTD PMID:25130202 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein] CTD PMID:25656916 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein] CTD PMID:25656916 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein] CTD PMID:25656916 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 multiple interactions EXP
ISO
myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFSF11 protein] CTD PMID:25130202 NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483
JBrowse link
G Trp53 transformation related protein 53 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein] CTD PMID:23639522 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22330
    role 22316
      chemical role 21571
        antioxidant 16467
          myricetin 126
            3',5,7-trihydroxy-3,4',5'-trimethoxyflavone 0
            3',5-dihydroxy-3,4',5',7-tetramethoxyflavone 0
            3,3',4',5'-tetramethylmyricetin 0
            3,3',5'-trimethylmyricetin 0
            5,7,3',5'-tetrahydroxy-3,4'-dimethyoxyflavone 0
            7,3',5'-trimethylmyricetin 0
            7-O-methylmyricetin 0
            combretol 0
            dihydromyricetin + 6
            laricitrin 0
            myricetin 3-O-[(6-O-trans-4-coumaroyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside] 0
            myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] + 0
            myricetin 3-O-beta-D-galactopyranoside 0
            myricetin 3-O-beta-L-galactopyranoside 0
            myricetin O-glucoside + 0
            myricetin O-glucuronide + 0
            myricetin-3-O-arabinofuranoside 0
            myricetin-3-O-beta-D-xylopyranoside 0
            myricitrin + 27
            syringetin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22330
    subatomic particle 22325
      composite particle 22325
        hadron 22325
          baryon 22325
            nucleon 22325
              atomic nucleus 22325
                atom 22325
                  main group element atom 22207
                    p-block element atom 22207
                      carbon group element atom 22010
                        carbon atom 21950
                          organic molecular entity 21950
                            organic molecule 21778
                              organic cyclic compound 21406
                                organic heterocyclic compound 20387
                                  oxacycle 18917
                                    benzopyran 12241
                                      1-benzopyran 12000
                                        flavonoid 7314
                                          anthoxanthin 4643
                                            flavones 4643
                                              hydroxyflavone 4619
                                                flavonols 4485
                                                  7-hydroxyflavonol 4417
                                                    myricetin 126
                                                      3',5,7-trihydroxy-3,4',5'-trimethoxyflavone 0
                                                      3',5-dihydroxy-3,4',5',7-tetramethoxyflavone 0
                                                      3,3',4',5'-tetramethylmyricetin 0
                                                      3,3',5'-trimethylmyricetin 0
                                                      5,7,3',5'-tetrahydroxy-3,4'-dimethyoxyflavone 0
                                                      7,3',5'-trimethylmyricetin 0
                                                      7-O-methylmyricetin 0
                                                      combretol 0
                                                      dihydromyricetin + 6
                                                      laricitrin 0
                                                      myricetin 3-O-[(6-O-trans-4-coumaroyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside] 0
                                                      myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] + 0
                                                      myricetin 3-O-beta-D-galactopyranoside 0
                                                      myricetin 3-O-beta-L-galactopyranoside 0
                                                      myricetin O-glucoside + 0
                                                      myricetin O-glucuronide + 0
                                                      myricetin-3-O-arabinofuranoside 0
                                                      myricetin-3-O-beta-D-xylopyranoside 0
                                                      myricitrin + 27
                                                      syringetin 0
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