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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:myricitrin
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Accession:CHEBI:70082 term browser browse the term
Definition:A glycosyloxyflavone that consists of myricetin attached to a alpha-L-rhamnopyranosyl residue at position 3 via a glycosidic linkage. Isolated from Myrica cerifera, it exhibits anti-allergic activity.
Synonyms:exact_synonym: 5,7-dihydroxy-4-oxo-2-(3,4,5-trihydroxyphenyl)-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside
 related_synonym: 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-benzopyran-4-one;   Formula=C21H20O12;   InChI=1S/C21H20O12/c1-6-14(26)17(29)18(30)21(31-6)33-20-16(28)13-9(23)4-8(22)5-12(13)32-19(20)7-2-10(24)15(27)11(25)3-7/h2-6,14,17-18,21-27,29-30H,1H3/t6-,14-,17+,18+,21-/m0/s1;   InChIKey=DCYOADKBABEMIQ-OWMUPTOHSA-N;   Myricetin 3-O-rhamnoside;   Myricitroside;   SMILES=C[C@@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)-c2cc(O)c(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O;   myricetin 3-O-alpha-L-rhamnopyranoside
 alt_id: CHEBI:7054
 xref: CAS:17912-87-7;   HMDB:HMDB0034360;   KEGG:C10108;   KNApSAcK:C00005730;   LIPID_MAPS_instance:LMPK12112436
 xref_mesh: MESH:C008577
 xref: PMID:21141876;   PMID:21315136;   PMID:21328132;   PMID:21689712;   PMID:23123269;   PMID:23265454;   Patent:US2012015090;   Patent:WO2010110334;   Reaxys:69806;   Wikipedia:Myricitrin
 cyclic_relationship: is_conjugate_acid_of CHEBI:144432



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myricitrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:25656916 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ALPL mRNA] CTD PMID:25130202 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
JBrowse link
G Apoe apolipoprotein E multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in decreased activity of CAT protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased activity of CASP3 protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CCL2 protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CRP protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of ICAM1 protein] CTD PMID:23639522 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein] CTD PMID:23639522 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:23639522 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BGLAP mRNA] CTD PMID:25130202 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Casp3 caspase 3 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]
myricitrin inhibits the reaction [APOE gene mutant form results in increased activity of CASP3 protein]
CTD PMID:23639522 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein]
myricitrin inhibits the reaction [APOE gene mutant form results in decreased activity of CAT protein]
CTD PMID:23639522 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CCL2 protein] CTD PMID:23639522 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of COL1A1 mRNA] CTD PMID:25130202 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Crp C-reactive protein multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CRP protein] CTD PMID:23639522 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein] CTD PMID:25656916 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein] CTD PMID:25656916 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of GPX1 protein] CTD PMID:23639522 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of ICAM1 protein] CTD PMID:23639522 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il6 interleukin 6 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of IL6 protein] CTD PMID:25130202 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein] CTD PMID:23639522 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein] CTD PMID:23639522 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:23639522 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of NOS3 protein] CTD PMID:23639522 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO myricitrin promotes the reaction [Carbon Tetrachloride results in increased expression of PCNA protein] CTD PMID:25656916 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of PPARG mRNA] CTD PMID:25130202 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein] CTD PMID:25656916 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein] CTD PMID:25656916 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein] CTD PMID:25656916 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFSF11 protein] CTD PMID:25130202 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein] CTD PMID:23639522 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20056
    role 20008
      chemical role 19544
        antioxidant 15014
          myricetin 115
            myricitrin 27
              myricitrin-5-methyl ether 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    p-block element atom 19956
                      carbon group element atom 19882
                        carbon atom 19875
                          organic molecular entity 19875
                            organic molecule 19822
                              organic cyclic compound 19575
                                organic heterocyclic compound 18798
                                  oxacycle 17684
                                    benzopyran 11207
                                      1-benzopyran 10945
                                        flavonoid 6570
                                          flavones 4217
                                            hydroxyflavone 4205
                                              flavonols 4108
                                                7-hydroxyflavonol 4086
                                                  myricetin 115
                                                    myricitrin 27
                                                      myricitrin-5-methyl ether 0
paths to the root