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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:myricitrin
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Accession:CHEBI:70082 term browser browse the term
Definition:A glycosyloxyflavone that consists of myricetin attached to a alpha-L-rhamnopyranosyl residue at position 3 via a glycosidic linkage. Isolated from Myrica cerifera, it exhibits anti-allergic activity.
Synonyms:exact_synonym: 5,7-dihydroxy-4-oxo-2-(3,4,5-trihydroxyphenyl)-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside
 related_synonym: 3-((6-deoxy-alpha-L-mannopyranosyl)oxy)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-benzopyran-4-one;   Formula=C21H20O12;   InChI=1S/C21H20O12/c1-6-14(26)17(29)18(30)21(31-6)33-20-16(28)13-9(23)4-8(22)5-12(13)32-19(20)7-2-10(24)15(27)11(25)3-7/h2-6,14,17-18,21-27,29-30H,1H3/t6-,14-,17+,18+,21-/m0/s1;   InChIKey=DCYOADKBABEMIQ-OWMUPTOHSA-N;   Myricetin 3-O-rhamnoside;   Myricitroside;   SMILES=C[C@@H]1O[C@@H](Oc2c(oc3cc(O)cc(O)c3c2=O)-c2cc(O)c(O)c(O)c2)[C@H](O)[C@H](O)[C@H]1O;   myricetin 3-O-alpha-L-rhamnopyranoside
 alt_id: CHEBI:7054
 xref: CAS:17912-87-7;   HMDB:HMDB0034360;   KEGG:C10108;   KNApSAcK:C00005730;   LIPID_MAPS_instance:LMPK12112436
 xref_mesh: MESH:C008577
 xref: PMID:21141876;   PMID:21315136;   PMID:21328132;   PMID:21689712;   PMID:23123269;   PMID:23265454;   Patent:US2012015090;   Patent:WO2010110334;   Reaxys:69806;   Wikipedia:Myricitrin
 cyclic_relationship: is_conjugate_acid_of CHEBI:144432


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myricitrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:25656916 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ALPL mRNA] CTD PMID:25130202 NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Apoe apolipoprotein E multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in decreased activity of CAT protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased activity of CASP3 protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CCL2 protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CRP protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of ICAM1 protein] CTD PMID:23639522 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein] CTD PMID:23639522 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:23639522 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BGLAP mRNA] CTD PMID:25130202 NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]
myricitrin inhibits the reaction [APOE gene mutant form results in increased activity of CASP3 protein]		 CTD PMID:23639522 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein]
myricitrin inhibits the reaction [APOE gene mutant form results in decreased activity of CAT protein]		 CTD PMID:23639522 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CCL2 protein] CTD PMID:23639522 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of COL1A1 mRNA] CTD PMID:25130202 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Crp C-reactive protein multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CRP protein] CTD PMID:23639522 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein] CTD PMID:25656916 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein] CTD PMID:25656916 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of GPX1 protein] CTD PMID:23639522 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of ICAM1 protein] CTD PMID:23639522 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of IL6 protein] CTD PMID:25130202 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein] CTD PMID:23639522 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein] CTD PMID:23639522 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:23639522 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of NOS3 protein] CTD PMID:23639522 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO myricitrin promotes the reaction [Carbon Tetrachloride results in increased expression of PCNA protein] CTD PMID:25656916 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of PPARG mRNA] CTD PMID:25130202 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein] CTD PMID:25656916 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein] CTD PMID:25656916 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein] CTD PMID:25656916 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFSF11 protein] CTD PMID:25130202 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein] CTD PMID:23639522 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    role 19858
      chemical role 19483
        antioxidant 16181
          myricetin 124
            myricitrin 27
              myricitrin-5-methyl ether 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    p-block element atom 19824
                      carbon group element atom 19763
                        carbon atom 19760
                          organic molecular entity 19760
                            organic molecule 19713
                              organic cyclic compound 19505
                                organic heterocyclic compound 18875
                                  oxacycle 17906
                                    benzopyran 11990
                                      1-benzopyran 11744
                                        flavonoid 7234
                                          anthoxanthin 4587
                                            flavones 4587
                                              hydroxyflavone 4564
                                                flavonols 4431
                                                  7-hydroxyflavonol 4396
                                                    myricetin 124
                                                      myricitrin 27
                                                        myricitrin-5-methyl ether 0
paths to the root