Rps6ka1 (ribosomal protein S6 kinase polypeptide 1) - Rat Genome Database

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Gene: Rps6ka1 (ribosomal protein S6 kinase polypeptide 1) Mus musculus
Analyze
Symbol: Rps6ka1
Name: ribosomal protein S6 kinase polypeptide 1
RGD ID: 732452
MGI Page MGI
Description: Enables DNA-binding transcription factor binding activity and kinase activity. Involved in hepatocyte proliferation. Located in spindle. Is active in synapse. Is expressed in central nervous system; early conceptus; lumbar dorsal root ganglion; oocyte; and retina. Orthologous to human RPS6KA1 (ribosomal protein S6 kinase A1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 90 kDa ribosomal protein S6 kinase 1; MAP kinase-activated protein kinase 1a; MAPK-activated protein kinase 1a; MAPKAP kinase 1a; Mapkapk-1a; p90-RSK 1; p90-Rsk1; p90rsk; p90Rsk1; p90S6K; ribosomal protein S6 kinase alpha-1; Ribosomal protein S6 kinase, 90kD, 1; ribosomal protein S6 kinase, 90kD, polypeptide 1; ribosomal S6 kinase 1; Rs; rsk; Rsk-1; Rsk1; S6K-alpha-1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394133,574,601 - 133,615,466 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4133,574,601 - 133,615,108 (-)EnsemblGRCm39 Ensembl
GRCm384133,847,290 - 133,887,797 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4133,847,290 - 133,887,797 (-)EnsemblGRCm38mm10GRCm38
MGSCv374133,403,205 - 133,443,714 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364133,119,370 - 133,159,860 (-)NCBIMGSCv36mm8
Celera4132,018,889 - 132,060,783 (-)NCBICelera
Cytogenetic Map4D2.3NCBI
cM Map466.37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (EXP)
(20R)-protopanaxadiol  (ISO)
1,2-dimethylhydrazine  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (EXP)
17alpha-ethynylestradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-palmitoylglycerol  (ISO)
6-propyl-2-thiouracil  (ISO)
9-cis-retinoic acid  (EXP)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amitrole  (ISO)
antirheumatic drug  (ISO)
arsenite(3-)  (EXP)
avermectin  (ISO)
benzo[a]pyrene  (EXP,ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
butanal  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
cisplatin  (ISO)
cobalt dichloride  (EXP)
cocaine  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (EXP)
dibutyl phthalate  (EXP)
diclofenac  (ISO)
doxorubicin  (EXP)
elemental selenium  (ISO)
enzacamene  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
fasudil  (ISO)
fenthion  (EXP)
flufenoxuron  (EXP)
folic acid  (EXP)
folpet  (EXP)
formaldehyde  (ISO)
FR900359  (ISO)
gallic acid  (ISO)
inulin  (EXP)
ivermectin  (ISO)
letrozole  (EXP)
lipopolysaccharide  (EXP)
LY294002  (EXP)
lycopene  (ISO)
methidathion  (EXP)
methyl methanesulfonate  (ISO)
myricetin  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (ISO)
nickel atom  (ISO)
Nodularin  (ISO)
ochratoxin A  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phorbol 13-acetate 12-myristate  (EXP)
pioglitazone  (ISO)
pirinixic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (EXP,ISO)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
selenium atom  (ISO)
selumetinib  (EXP)
sirolimus  (EXP,ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP,ISO)
Soman  (ISO)
SU6656  (ISO)
sulfadimethoxine  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
titanium dioxide  (EXP)
toluene  (ISO)
tungsten  (EXP)
vitamin E  (ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. MAPKAP kinases - MKs - two's company, three's a crowd. Gaestel M Nat Rev Mol Cell Biol. 2006 Feb;7(2):120-30.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
8. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:2779569   PMID:8262198   PMID:8524831   PMID:9560223   PMID:9858555   PMID:10349636   PMID:10635333   PMID:10862698   PMID:10922068   PMID:11042159   PMID:11076861   PMID:12393804  
PMID:12477932   PMID:12520002   PMID:12618428   PMID:12769834   PMID:14610273   PMID:14622137   PMID:15009138   PMID:15107468   PMID:15226426   PMID:15305288   PMID:15327787   PMID:15509711  
PMID:15741177   PMID:15782199   PMID:15893597   PMID:15895362   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16738324   PMID:17043309   PMID:17494629   PMID:17664275   PMID:17938253  
PMID:17967808   PMID:18799693   PMID:19114553   PMID:19570980   PMID:20515922   PMID:20557427   PMID:21148481   PMID:21267068   PMID:21421818   PMID:21609719   PMID:21677750   PMID:21873635  
PMID:22006917   PMID:22041125   PMID:22130794   PMID:22794259   PMID:22797923   PMID:23209321   PMID:23243209   PMID:23624076   PMID:24307699   PMID:24416220   PMID:24457600   PMID:24552586  
PMID:24967341   PMID:25211037   PMID:25332232   PMID:26401001   PMID:26410627   PMID:26848828   PMID:27063456   PMID:27246400   PMID:28162770   PMID:29229781   PMID:29473817   PMID:30586719  
PMID:32325033   PMID:32581239   PMID:37068088  


Genomics

Comparative Map Data
Rps6ka1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394133,574,601 - 133,615,466 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4133,574,601 - 133,615,108 (-)EnsemblGRCm39 Ensembl
GRCm384133,847,290 - 133,887,797 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4133,847,290 - 133,887,797 (-)EnsemblGRCm38mm10GRCm38
MGSCv374133,403,205 - 133,443,714 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364133,119,370 - 133,159,860 (-)NCBIMGSCv36mm8
Celera4132,018,889 - 132,060,783 (-)NCBICelera
Cytogenetic Map4D2.3NCBI
cM Map466.37NCBI
RPS6KA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,529,761 - 26,575,025 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl126,529,761 - 26,575,030 (+)EnsemblGRCh38hg38GRCh38
GRCh37126,856,252 - 26,901,516 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,728,836 - 26,774,107 (+)NCBINCBI36Build 36hg18NCBI36
Build 34126,540,390 - 26,585,662NCBI
Celera125,253,435 - 25,298,712 (+)NCBICelera
Cytogenetic Map1p36.11NCBI
HuRef125,110,498 - 25,155,787 (+)NCBIHuRef
CHM1_1126,969,231 - 27,014,507 (+)NCBICHM1_1
T2T-CHM13v2.0126,367,713 - 26,412,979 (+)NCBIT2T-CHM13v2.0
Rps6ka1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85151,362,819 - 151,402,064 (-)NCBIGRCr8
mRatBN7.25146,079,018 - 146,118,272 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5146,079,021 - 146,118,272 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5148,781,620 - 148,820,794 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05150,551,233 - 150,590,407 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05150,537,805 - 150,576,980 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05152,078,217 - 152,122,684 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5152,078,220 - 152,122,684 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05155,760,609 - 155,805,563 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45151,274,666 - 151,288,007 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15151,284,704 - 151,298,043 (+)NCBI
Celera5144,500,101 - 144,539,235 (-)NCBICelera
Cytogenetic Map5q36NCBI
Rps6ka1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554525,904,762 - 5,939,091 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554525,905,561 - 5,938,096 (+)NCBIChiLan1.0ChiLan1.0
RPS6KA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21200,294,769 - 200,340,289 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11199,395,353 - 199,440,930 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0125,792,428 - 25,837,950 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1126,856,061 - 26,900,532 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,856,057 - 26,900,532 (+)Ensemblpanpan1.1panPan2
RPS6KA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1273,497,128 - 73,533,853 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl273,497,473 - 73,534,378 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha270,074,045 - 70,110,763 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0274,060,131 - 74,097,008 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl274,060,131 - 74,097,510 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1270,884,942 - 70,921,656 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0271,890,665 - 71,927,571 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0272,894,123 - 72,930,845 (-)NCBIUU_Cfam_GSD_1.0
Rps6ka1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505845,171,987 - 45,205,720 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647410,996,813 - 11,030,557 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647410,996,867 - 11,030,504 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPS6KA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl683,905,077 - 83,950,963 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1683,905,124 - 83,947,189 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2677,443,084 - 77,480,448 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RPS6KA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120106,180,708 - 106,226,636 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20106,180,418 - 106,226,552 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603310,197,449 - 10,243,985 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rps6ka1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476410,526,948 - 10,569,910 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476410,527,012 - 10,566,625 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rps6ka1
1492 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2154
Count of miRNA genes:637
Interacting mature miRNAs:775
Transcripts:ENSMUST00000003741, ENSMUST00000105894, ENSMUST00000129636, ENSMUST00000137486, ENSMUST00000157067, ENSMUST00000168974, ENSMUST00000173961, ENSMUST00000173989, ENSMUST00000174481
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156268235Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138342753Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155684457Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465718237146584457Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468018237150884457Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined88982069140468203Mouse
4141549W10q10_mweight 10 weeks QTL 10 (mouse)Not determined88982069140468203Mouse
4141093W3q17_mweight 3 weeks QTL 17 (mouse)Not determined88982069140468203Mouse
39128212Lwq21_mliver weight QTL 21 (mouse)488982069140468203Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined488982069151654550Mouse
13208562Wght7_mweight 7 (mouse)490888237148084457Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined494957579150676858Mouse
1301106Skts7_mskin tumor susceptibility 7 (mouse)Not determined4100071971134072206Mouse
1301847Fecq2_mfecundity QTL 2 (mouse)Not determined4100071971134072206Mouse
12880433Fgf23lq1_mFGF23 serum level QTL 1 (mouse)4101157197135157197Mouse
15039377Bw45_mbody weight QTL 45 (mouse)4105705794139705794Mouse
15039378Adip30_madiposity 30 (mouse)4105705794139705794Mouse
15039382Ltgq7_mliver triglyceride QTL 7 (mouse)4105705794139705794Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105835310141433838Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105835310141433838Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105835310141433838Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105835310141433838Mouse
1357800Tgq3_mtriglyceride QTL 3 (mouse)Not determined4107055093141055180Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107264957141265153Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107264957141265153Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107264957141265153Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107791564141791756Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108477692142477692Mouse
10755521Hct1_mhematocrit 1 (mouse)4108477692142477692Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108477692142477692Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111009051145009280Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111009051145009280Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112182386146182386Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112523489146523489Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112824389146824389Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116154678150154782Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117401141151401275Mouse
14746982Manh56_mmandible shape 56 (mouse)4117815917151815917Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4119864433153864536Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4119864433153864536Mouse
13503348Bntq18_mbone traits QTL 18 (mouse)4120617848154617995Mouse
10412210Cypr6_mcytokine production 6 (mouse)Not determined4120617848154617995Mouse
4141180Ssic1_msusceptibility to small intestinal cancer 1 (mouse)Not determined120674005154674151Mouse
1300803Sluc6_msusceptibility to lung cancer 6 (mouse)Not determined4120674005154674151Mouse
10043985Stheal12_msoft tissue heal 12 (mouse)Not determined4121342649155342753Mouse
4142061Chlq16_mcirculating hormone level QTL 16 (mouse)Not determined4121342649155342753Mouse
1301452Elsgp1_melevated serum gp70 1 (mouse)Not determined4121342649155342753Mouse
27226757Femd1_mfemur midshaft diameter 1, 5 week (mouse)4123993793144326570Mouse
4141065Shali2_msurvival time to hyperoxic acute lung injury 2 (mouse)Not determined124055093141572792Mouse
1300917Gasa1_mgastritis type A susceptibility locus 1 (mouse)Not determined4124055093142438020Mouse
1302149Tlsr2_mthymic lymphoma suppressor region 2 (mouse)Not determined4124264957142230960Mouse
1301525Lmb1_mlupus in MRL and B6 F2 cross (mouse)Not determined4124264957150676858Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124553483156860686Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124621281156860686Mouse
4142139Adip12_madiposity 12 (mouse)Not determined4124621281156860686Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124621281156860686Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125230872156860686Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125230872156860686Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125230872156860686Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125289325156860686Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4127784226156860686Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4127784226156860686Mouse
1301793Tlsr3_mthymic lymphoma suppressor region 3 (mouse)Not determined4129465811136864536Mouse
1301584Lrdg2_mlight induced retinal degeneration 2 (mouse)Not determined4129465811151654550Mouse
25394568Skmw56_mskeletal muscle weight 56, EDL (mouse)4129859344133710576Mouse
12904009Cfq9_mconditioned fear QTL 9 (mouse)4130036287133772722Mouse
25394567Skmw55_mskeletal muscle weight 55, gastroc (mouse)4131437804133710576Mouse
4141154Nba1_mNew Zealand Black autoimmunity 1 (mouse)Not determined131650724140879275Mouse
14696808Rbcn1_mrod bipolar cell number 1 (mouse)4131947311134047311Mouse
1300874Gasa2_mgastritis type A susceptibility locus 2 (mouse)Not determined4133010494156860686Mouse
4142082Psds2_mpsoriasis-like skin disease severity 2 (mouse)Not determined4133154678137617995Mouse
1301267Bcmd2_mB cell maturation defect 2 (mouse)Not determined4133154678150789451Mouse

Markers in Region
Rps6ka1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Celera4132,019,243 - 132,019,638UniSTS
Cytogenetic Map4D3UniSTS
cM Map4 UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001285505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001285506 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001378880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036163924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF084468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK148208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160571 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL837508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC049076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC094470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY226173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY737295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA547794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M28489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSMUST00000003741   ⟹   ENSMUSP00000003741
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4133,574,605 - 133,615,095 (-)Ensembl
GRCm38.p6 Ensembl4133,847,294 - 133,887,784 (-)Ensembl
RefSeq Acc Id: ENSMUST00000105894   ⟹   ENSMUSP00000101514
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4133,574,601 - 133,615,108 (-)Ensembl
GRCm38.p6 Ensembl4133,847,290 - 133,887,797 (-)Ensembl
RefSeq Acc Id: ENSMUST00000129636
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4133,587,476 - 133,588,353 (-)Ensembl
GRCm38.p6 Ensembl4133,860,165 - 133,861,042 (-)Ensembl
RefSeq Acc Id: ENSMUST00000137486   ⟹   ENSMUSP00000119328
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4133,575,363 - 133,600,350 (-)Ensembl
GRCm38.p6 Ensembl4133,848,052 - 133,873,039 (-)Ensembl
RefSeq Acc Id: ENSMUST00000157067   ⟹   ENSMUSP00000121341
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4133,575,136 - 133,599,624 (-)Ensembl
GRCm38.p6 Ensembl4133,847,825 - 133,872,313 (-)Ensembl
RefSeq Acc Id: ENSMUST00000168974   ⟹   ENSMUSP00000126774
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4133,574,605 - 133,602,042 (-)Ensembl
GRCm38.p6 Ensembl4133,847,294 - 133,874,731 (-)Ensembl
RefSeq Acc Id: ENSMUST00000173961
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4133,599,275 - 133,614,885 (-)Ensembl
GRCm38.p6 Ensembl4133,871,964 - 133,887,574 (-)Ensembl
RefSeq Acc Id: ENSMUST00000173989
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4133,577,868 - 133,588,241 (-)Ensembl
GRCm38.p6 Ensembl4133,850,557 - 133,860,930 (-)Ensembl
RefSeq Acc Id: ENSMUST00000174481   ⟹   ENSMUSP00000134507
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl4133,575,274 - 133,613,594 (-)Ensembl
GRCm38.p6 Ensembl4133,847,963 - 133,886,283 (-)Ensembl
RefSeq Acc Id: NM_001285505   ⟹   NP_001272434
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394133,574,601 - 133,615,108 (-)NCBI
GRCm384133,847,290 - 133,887,797 (-)NCBI
Celera4132,018,889 - 132,060,781 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001285506   ⟹   NP_001272435
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394133,574,601 - 133,602,042 (-)NCBI
GRCm384133,847,290 - 133,874,731 (-)NCBI
Celera4132,018,889 - 132,060,781 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001378880   ⟹   NP_001365809
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394133,574,601 - 133,600,346 (-)NCBI
GRCm384133,847,290 - 133,873,035 (-)NCBI
Sequence:
RefSeq Acc Id: NM_009097   ⟹   NP_033123
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394133,574,601 - 133,615,108 (-)NCBI
GRCm384133,847,290 - 133,887,797 (-)NCBI
MGSCv374133,403,205 - 133,443,714 (-)RGD
Celera4132,018,889 - 132,060,781 (-)NCBI
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036163924   ⟹   XP_036019817
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394133,574,601 - 133,615,466 (-)NCBI
Sequence:
RefSeq Acc Id: NP_033123   ⟸   NM_009097
- Peptide Label: isoform a
- UniProtKB: Q505N6 (UniProtKB/TrEMBL),   Q3UFZ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001272434   ⟸   NM_001285505
- Peptide Label: isoform b
- UniProtKB: P18653 (UniProtKB/Swiss-Prot),   Q3UFZ5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001272435   ⟸   NM_001285506
- Peptide Label: isoform c
- UniProtKB: E9PWV3 (UniProtKB/TrEMBL),   Q3TIM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001365809   ⟸   NM_001378880
- Peptide Label: isoform d
- UniProtKB: F6Q8A4 (UniProtKB/TrEMBL),   Q3TIM6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000101514   ⟸   ENSMUST00000105894
RefSeq Acc Id: ENSMUSP00000134507   ⟸   ENSMUST00000174481
RefSeq Acc Id: ENSMUSP00000003741   ⟸   ENSMUST00000003741
RefSeq Acc Id: ENSMUSP00000126774   ⟸   ENSMUST00000168974
RefSeq Acc Id: ENSMUSP00000119328   ⟸   ENSMUST00000137486
RefSeq Acc Id: ENSMUSP00000121341   ⟸   ENSMUST00000157067
RefSeq Acc Id: XP_036019817   ⟸   XM_036163924
- Peptide Label: isoform X1
- UniProtKB: Q505N6 (UniProtKB/TrEMBL),   Q3UFZ5 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P18653-F1-model_v2 AlphaFold P18653 1-724 view protein structure

Promoters
RGD ID:6836323
Promoter ID:MM_KWN:40043
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Brain,   Kidney,   Lung
Transcripts:OTTMUST00000022378
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364133,416,509 - 133,417,009 (-)MPROMDB
RGD ID:6836324
Promoter ID:MM_KWN:40045
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Liver
Transcripts:UC008VDL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364133,428,021 - 133,429,032 (-)MPROMDB
RGD ID:6836321
Promoter ID:MM_KWN:40046
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Lung,   Spleen
Transcripts:OTTMUST00000022377
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364133,428,771 - 133,429,572 (-)MPROMDB
RGD ID:6836325
Promoter ID:MM_KWN:40047
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain
Transcripts:OTTMUST00000022376,   UC008VDM.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364133,430,084 - 133,430,584 (-)MPROMDB
RGD ID:6836326
Promoter ID:MM_KWN:40048
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:UC008VDP.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364133,436,861 - 133,437,712 (-)MPROMDB
RGD ID:6836318
Promoter ID:MM_KWN:40050
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   Spleen
Transcripts:OTTMUST00000022181,   OTTMUST00000022256,   UC008VDK.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364133,443,556 - 133,444,237 (-)MPROMDB
RGD ID:6884976
Promoter ID:EPDNEW_M5939
Type:initiation region
Name:Rps6ka1_3
Description:Mus musculus ribosomal protein S6 kinase polypeptide 1 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M5940  EPDNEW_M5941  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384133,873,035 - 133,873,095EPDNEW
RGD ID:6884978
Promoter ID:EPDNEW_M5940
Type:initiation region
Name:Rps6ka1_2
Description:Mus musculus ribosomal protein S6 kinase polypeptide 1 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M5939  EPDNEW_M5941  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384133,874,701 - 133,874,761EPDNEW
RGD ID:6884986
Promoter ID:EPDNEW_M5941
Type:initiation region
Name:Rps6ka1_1
Description:Mus musculus ribosomal protein S6 kinase polypeptide 1 , transcriptvariant 2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M5939  EPDNEW_M5940  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384133,887,789 - 133,887,849EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:104558 AgrOrtholog
Ensembl Genes ENSMUSG00000003644 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000003741 ENTREZGENE
  ENSMUST00000003741.16 UniProtKB/Swiss-Prot
  ENSMUST00000105894 ENTREZGENE
  ENSMUST00000105894.11 UniProtKB/TrEMBL
  ENSMUST00000137486 ENTREZGENE
  ENSMUST00000137486.3 UniProtKB/TrEMBL
  ENSMUST00000157067.9 UniProtKB/TrEMBL
  ENSMUST00000168974 ENTREZGENE
  ENSMUST00000168974.9 UniProtKB/TrEMBL
  ENSMUST00000174481.8 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AGC-kinase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S6_kinase_II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RSK_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:20111 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:104558 ENTREZGENE
NCBI Gene 20111 ENTREZGENE
PANTHER CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE UniProtKB/TrEMBL
  RIBOSOMAL PROTEIN S6 KINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RIBOSOMAL PROTEIN S6 KINASE ALPHA-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rps6ka1 PhenoGen
PIRSF Ribsml_S6_kin_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE AGC_KINASE_CTER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART S_TK_X UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt E9PWV3 ENTREZGENE, UniProtKB/TrEMBL
  F6Q8A4 ENTREZGENE, UniProtKB/TrEMBL
  F6RQA2_MOUSE UniProtKB/TrEMBL
  G3UZI3_MOUSE UniProtKB/TrEMBL
  KS6A1_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TIM6 ENTREZGENE, UniProtKB/TrEMBL
  Q3UFZ5 ENTREZGENE, UniProtKB/TrEMBL
  Q505N6 ENTREZGENE, UniProtKB/TrEMBL
  Q810V8_MOUSE UniProtKB/TrEMBL
  Q9Z278_MOUSE UniProtKB/TrEMBL