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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 732452
Species: Mus musculus
RGD Object: Gene
Symbol: Rps6ka1
Name: ribosomal protein S6 kinase polypeptide 1
Acc ID: CHEBI:16412
Term: lipopolysaccharide
Definition: Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID: MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rps6ka1decreases expressionEXP 6480464CTDLipopolysaccharides results in decreased expression of RPS6KA1 mRNAPMID:12057914
Rps6ka1increases activityEXP 6480464CTDLipopolysaccharides results in increased activity of RPS6KA1 proteinPMID:10998351
Rps6ka1multiple interactionsEXP 6480464CTDU 0126 inhibits the reaction [Lipopolysaccharides results in increased activity of RPS6KA1 protein]PMID:10998351
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