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Gene: RPS6KA6 (ribosomal protein S6 kinase A6) Homo sapiens
Symbol: RPS6KA6
Name: ribosomal protein S6 kinase A6
Description: Predicted to have ribosomal protein S6 kinase activity. Involved in DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator. Localizes to the fibrillar center; mitochondrion; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 90 kDa ribosomal protein S6 kinase 6; p90-RSK 6; p90RSK6; PP90RSK4; ribosomal protein S6 kinase alpha-6; ribosomal protein S6 kinase, 90kDa, polypeptide 6; ribosomal S6 kinase 4; RSK-4; RSK4; S6K-alpha 6; S6K-alpha-6
Mus musculus (house mouse) : Rps6ka6 (ribosomal protein S6 kinase polypeptide 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rps6ka6 (ribosomal protein S6 kinase A6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rps6ka6 (ribosomal protein S6 kinase A6)
Pan paniscus (bonobo/pygmy chimpanzee) : RPS6KA6 (ribosomal protein S6 kinase A6)
Canis lupus familiaris (dog) : RPS6KA6 (ribosomal protein S6 kinase A6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rps6ka6 (ribosomal protein S6 kinase A6)
Sus scrofa (pig) : RPS6KA6 (ribosomal protein S6 kinase A6)
Chlorocebus sabaeus (African green monkey) : RPS6KA6 (ribosomal protein S6 kinase A6)
Heterocephalus glaber (naked mole-rat) : Rps6ka6 (ribosomal protein S6 kinase A6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX84,058,346 - 84,188,199 (-)Ensembl
GRCh38X84,058,346 - 84,188,199 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X83,313,354 - 83,442,943 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X83,205,640 - 84,362,350 (-)NCBINCBI36hg18NCBI36
Build 34X83,125,128 - 83,254,098NCBI
CeleraX83,550,763 - 83,681,714 (-)NCBI
Cytogenetic MapXq21.1NCBI
HuRefX76,885,898 - 76,994,131 (-)NCBIHuRef
CHM1_1X83,207,273 - 83,336,842 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RPS6KA6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350176
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.