Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

Ontology Browser
Term:
Parent Terms Term With Siblings Child Terms
geroprotector +   
malic acid +     
(+)-catechin monohydrate 
(-)-epigallocatechin 3-gallate +   
(-)-selegiline  
(E)-10-hydroxydec-2-enoic acid +   
(R)-malic acid +  
(R)-pantothenic acid +   
(R)-rosmarinic acid 
(R,R)-5,11-diethyl-5,6,11,12-tetrahydro-2,8-chrysenediol 
(S)-malic acid +  
An optically active form of malic acid having (S)-configuration.
1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose 
1-[1-(1-benzothiophen-2-yl)cyclohexyl]piperidine hydrochloride 
17alpha-estradiol +   
17beta-estradiol +   
1D-chiro-inositol +  
2,3-dimethylmalic acid +  
2,4-dinitrophenol +   
2,5-dihydroxycinnamic acid methyl ester  
2,5-dimethylcelecoxib  
2,6-di-tert-butyl-4-methylphenol  
2-(1,3-benzothiazol-2-yl)phenol 
2-(1,3-benzoxazol-2-yl)phenol 
2-(1H-benzimidazol-2-yl)aniline 
2-(2-amino-3-methoxyphenyl)chromen-4-one 
2-(4-hydroxyphenyl)ethanol +   
2-(omega-methylthio)alkylmalic acid +  
2-(p-coumaroyl)malic acid 
2-amino-2-deoxy-D-glucopyranose +   
2-deoxy-D-glucose +   
2-hydroxy-3-(2-methylidenecyclopropyl)butanedioic acid 
2-oxoglutarate(2-) 
2-phosphinomethylmalic acid 
3,3-diethyl-2-pyrrolidinone 
3,4-dichloroisocoumarin 
3-(omega-methylthio)alkylmalic acid +  
3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-diphenylpropan-2-ol 
3-carboxy-3-hydroxypropanoyl-CoA 
4'-O-methyl-(-)-epicatechin 
4,5-dianilinophthalimide  
4-phenyl-3-furoxancarbonitrile  
6,7-dimethyl-2-phenylquinoxaline 
7-amino-2-(ethylsulfanyl)-5-oxo-1-phenyl-1,5-dihydro[1,2,4]triazolo[1,5-a]pyridine-6,8-dicarbonitrile 
acarbose +   
acetylsalicylic acid +   
alpha,alpha-trehalose +   
AMN082 dihydrochloride 
amoxapine  
amperozide  
amperozide hydrochloride 
anthra[1,9-cd]pyrazol-6(2H)-one  
bacitracin  
baicalein +   
beauveriolide I 
berberine  
beta-maltose +   
bezafibrate  
BRL-50481 
buformin 
butein  
C60 fullerene  
caffeine +   
calciol +   
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  
carnosine +   
CCCP  
celecoxib  
chicoric acid  
chloramphenicol +   
chlorprothixene hydrochloride 
ciclopirox olamine 
cinnarizine  
cis-flupenthixol dihydrochloride 
clofibrate  
creatine +   
curcumin +   
cyclosporin A +   
cyproterone acetate  
cysteamine +   
D-pinitol 
dafadine A 
danazol  
demeclocycline +   
diazaborine +  
dibromoacetic acid  
dichloroacetate 
didanosine  
dihydroergocristine mesylate +  
dimethyl sulfoxide +   
doxazosin mesylate 
doxycycline +   
doxycycline HCl +  
EDTA monocalcium diisodium salt 
eliprodil  
ellagic acid +   
enalapril +   
ethidium bromide 
ethosuximide +   
ethoxyquin  
ethylenediaminetetraacetic acid  
EUK-134  
EUK-8 
everolimus  
fasudil  
fenofibrate  
ferulsinaic acid 
fisetin +   
fumaric acid +   
gallic acid +   
genistein +   
glaucarubinone 
glutathione +   
glycerol +   
Guanabenz acetate 
Guanfacine hydrochloride 
ibuprofen +   
indirubin  
isoliquiritigenin +   
juglone  
kaempferol +   
kanamycin A sulfate 
kenpaullone  
ketanserin tartrate 
kinetin +  
KN-93  
L-744,832 
L-ascorbic acid +   
L-methionine sulfoximine +  
L-thioproline +  
lamotrigine  
latrepirdine 
LFM-A13 
lipoic acid +   
lithium chloride  
lithocholic acid +   
lonidamine +   
loratadine  
loxapine succinate 
LY-165163 
LY-367,265 
LY294002  
magnesium(2+) +  
malate ester +   
Malonoben  
melatonin +   
mercaptoethanol +   
metergoline  
metformin  
methiothepin  
Methylergonovine Maleate  
metoprolol  
mianserin +   
mianserin hydrochloride 
minocycline +   
minocycline hydrochloride 
mochimganine 
morphine +   
myricetin +   
myxothiazol  
N(5)-ethyl-L-glutamine  
N,N-dimethylformamide +   
N-[3-(aminomethyl)benzyl]acetamidine  
N-acetyl-L-cysteine +   
N-nitrosodimethylamine  
N-ribosylnicotinamide  
NAD zwitterion  
naphthalene-1,2,3,4-tetrone +  
naphthazarin  
nebivolol  
nicardipine hydrochloride 
nicotinamide +   
nitrendipine  
nitroflurbiprofen  
nomilin  
nordihydroguaiaretic acid +   
Nortriptyline hydrochloride 
oleoyl ethanolamide +   
oxaloacetic acid +   
oxatomide  
paracetamol +   
paraquat +   
paxilline  
pergolide mesylate 
phenformin  
phosphonoformic acid +   
piceatannol +   
pioglitazone +   
PP2 
promethazine hydrochloride 
psora 4 
pyrrolidine dithiocarbamate  
quercetin +   
quercetin 3-O-beta-D-glucopyranoside  
quinidine sulfate 
resveratrol +   
rifampicin +   
RK-24466 
SB 203580  
simvastatin  
sirolimus +   
sodium butyrate 
sodium phenylbutyrate 
sodium valproate +   
spermidine +   
staurosporine +   
SU4312 
tannic acid  
thioflavine T  
thioridazine hydrochloride 
trametinib +   
trans-caffeic acid +   
trans-piceid  
trichostatin A +   
trimethadione 
tris(picolinato)chromium  
tschimganine 
tyrphostin 1 
tyrphostin AG 1478  
tyrphostin B42  
Urolithin A  
ursolic acid +   
valpromide  
vincristine sulfate 
Vinpocetine  
wortmannin +   

Synonyms
Related Synonyms: (2S)-2-hydroxybutanedioic acid ;   (S)-(-)-Hydroxysuccinic acid ;   Formula=C4H6O5 ;   InChI=1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)/t2-/m0/s1 ;   InChIKey=BJEPYKJPYRNKOW-REOHCLBHSA-N ;   L-2-Hydroxybutanedioic acid ;   L-Apple acid ;   L-malic acid ;   Malate ;   Malic acid
Alternate IDs: CHEBI:18785 ;   CHEBI:423
Xrefs: CAS:97-67-6 ;   HMDB:HMDB0000156 ;   KEGG:C00149 ;   KNApSAcK:C00001192 ;   MetaCyc:MAL ;   PDBeChem:LMR ;   PMID:22452826 ;   PMID:23472183 ;   Reaxys:1723541
Cyclic Relationships: is_conjugate_acid_of CHEBI:15589 ;   is_enantiomer_of CHEBI:30796

paths to the root