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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-phenyl-3-furoxancarbonitrile
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Accession:CHEBI:180495 term browser browse the term
Definition:A 1,2,5-oxadiazole substituted by an oxido, cyano and phenyl groups at positions 2, 3 and 4, respectively. It is a vasodilator and inhibitor of platelet aggregation.
Synonyms:exact_synonym: 4-phenyl-1,2,5-oxadiazole-3-carbonitrile 2-oxide
 related_synonym: 2-oxo-4-phenyl-1,2,5lambda(5)-oxadiazole-3-carbonitrile;   3-cyano-4-phenylfurazan 2-oxide;   Formula=C9H5N3O2;   InChI=1S/C9H5N3O2/c10-6-8-9(11-14-12(8)13)7-4-2-1-3-5-7/h1-5H;   InChIKey=PMYJGTWUVVVOFO-UHFFFAOYSA-N;   RVC-589;   SMILES=[O-][N+]1=C(C#N)C(=NO1)C1=CC=CC=C1
 xref: CAS:125520-62-9;   Chemspider:1692
 xref_mesh: MESH:C090933
 xref: PMID:11700955;   PMID:14513374;   PMID:15453262;   PMID:18235848;   PMID:18345010;   PMID:19761212;   PMID:20684594;   PMID:22830992;   PMID:24134630;   PMID:25016371;   PMID:26239395;   PMID:7996554;   PMID:9090611



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4-phenyl-3-furoxancarbonitrile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO 4-phenyl-3-furoxancarbonitrile results in increased expression of GCLC mRNA
4-phenyl-3-furoxancarbonitrile analog results in increased expression of GCLC mRNA
CTD PMID:22851183 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO 4-phenyl-3-furoxancarbonitrile results in increased expression of GCLM mRNA CTD PMID:22851183 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO 4-phenyl-3-furoxancarbonitrile results in increased expression of NQO1 mRNA CTD PMID:22851183 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link

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  CHEBI ontology 19917
    role 19887
      chemical role 19514
        donor 18960
          nitric oxide donor 2785
            4-phenyl-3-furoxancarbonitrile 3
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Term Annotations click to browse term
  CHEBI ontology 19917
    subatomic particle 19915
      composite particle 19915
        hadron 19915
          baryon 19915
            nucleon 19915
              atomic nucleus 19915
                atom 19915
                  main group element atom 19855
                    p-block element atom 19855
                      carbon group element atom 19794
                        carbon atom 19790
                          organic molecular entity 19790
                            organic molecule 19743
                              organic cyclic compound 19533
                                organic heterocyclic compound 18900
                                  organic heteromonocyclic compound 17827
                                    oxadiazole 34
                                      1,2,5-oxadiazole 20
                                        4-phenyl-3-furoxancarbonitrile 3
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