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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-phenyl-3-furoxancarbonitrile
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Accession:CHEBI:180495 term browser browse the term
Definition:A 1,2,5-oxadiazole substituted by an oxido, cyano and phenyl groups at positions 2, 3 and 4, respectively. It is a vasodilator and inhibitor of platelet aggregation.
Synonyms:exact_synonym: 4-phenyl-1,2,5-oxadiazole-3-carbonitrile 2-oxide
 related_synonym: 2-oxo-4-phenyl-1,2,5lambda(5)-oxadiazole-3-carbonitrile;   3-cyano-4-phenylfurazan 2-oxide;   Formula=C9H5N3O2;   InChI=1S/C9H5N3O2/c10-6-8-9(11-14-12(8)13)7-4-2-1-3-5-7/h1-5H;   InChIKey=PMYJGTWUVVVOFO-UHFFFAOYSA-N;   RVC-589;   SMILES=[O-][N+]1=C(C#N)C(=NO1)C1=CC=CC=C1
 xref: CAS:125520-62-9;   Chemspider:1692
 xref_mesh: MESH:C090933
 xref: PMID:11700955;   PMID:14513374;   PMID:15453262;   PMID:18235848;   PMID:18345010;   PMID:19761212;   PMID:20684594;   PMID:22830992;   PMID:24134630;   PMID:25016371;   PMID:26239395;   PMID:7996554;   PMID:9090611



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4-phenyl-3-furoxancarbonitrile term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO 4-phenyl-3-furoxancarbonitrile results in increased expression of GCLC mRNA
4-phenyl-3-furoxancarbonitrile analog results in increased expression of GCLC mRNA
CTD PMID:22851183 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO 4-phenyl-3-furoxancarbonitrile results in increased expression of GCLM mRNA CTD PMID:22851183 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO 4-phenyl-3-furoxancarbonitrile results in increased expression of NQO1 mRNA CTD PMID:22851183 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link

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  CHEBI ontology 20039
    role 19990
      chemical role 19519
        donor 18828
          nitric oxide donor 2771
            4-phenyl-3-furoxancarbonitrile 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 20039
    subatomic particle 20037
      composite particle 20037
        hadron 20037
          baryon 20037
            nucleon 20037
              atomic nucleus 20037
                atom 20037
                  main group element atom 19938
                    p-block element atom 19938
                      carbon group element atom 19861
                        carbon atom 19852
                          organic molecular entity 19852
                            organic molecule 19798
                              organic cyclic compound 19560
                                organic heterocyclic compound 18776
                                  organic heteromonocyclic compound 17161
                                    oxadiazole 27
                                      1,2,5-oxadiazole 16
                                        4-phenyl-3-furoxancarbonitrile 3
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