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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:eliprodil
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Accession:CHEBI:91784 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-eliprodil. It is a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist and an anti-ischaemic agent that exhibits neuroprotective properties.
Synonyms:exact_synonym: rac-1-(4-chlorophenyl)-2-[4-(4-fluorobenzyl)piperidin-1-yl]ethanol
 related_synonym: (+-)-alpha-(p-chlorophenyl)-4-(p-fluorobenzyl)-1-piperidineethanol;   (RS)-eliprodil;   Formula=C20H23ClFNO;   SL-82,0715;   SL-820715;   SL820715;   eliprodilum;   rac-1-(4-chlorophenyl)-2-{4-[(4-fluorophenyl)methyl]piperidin-1-yl}ethan-1-ol;   racemic eliprodil
 xref: CAS:119431-25-3;   Chemspider:54708;   DrugBank:DB12869;   HMDB:HMDB0251748;   LINCS:LSM-1677
 xref_mesh: MESH:C058083
 xref: PMID:10235550;   PMID:10235551;   PMID:10890168;   PMID:1354073;   PMID:15064913;   PMID:15302678;   PMID:24134630;   PMID:2849668;   PMID:29191857;   PMID:7814824;   PMID:8088348;   PMID:8402196;   PMID:8545484;   PMID:8719234;   PMID:8901012;   PMID:9089691;   PMID:9128850;   PMID:9369990;   PMID:9439799;   PMID:9519265;   PMID:9674557;   PMID:9718264;   PMID:9874159;   PMID:9932955;   Patent:EP0718407;   Wikipedia:Eliprodil


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eliprodil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO eliprodil inhibits the reaction [KCNH2 protein results in increased transport of Thallium] CTD PMID:19583963 NCBI chr 4:11,719,357...11,751,424
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20845
    chemical entity 20843
      chemical substance 14567
        mixture 13885
          racemate 12274
            eliprodil 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 20845
    subatomic particle 20843
      composite particle 20843
        hadron 20843
          baryon 20843
            nucleon 20843
              atomic nucleus 20843
                atom 20843
                  main group element atom 20766
                    main group molecular entity 20766
                      s-block molecular entity 20561
                        hydrogen molecular entity 20545
                          hydrides 19679
                            inorganic hydride 18572
                              pnictogen hydride 18558
                                nitrogen hydride 18469
                                  azane 18229
                                    ammonia 18228
                                      organic amino compound 18228
                                        tertiary amino compound 10243
                                          1-(4-chlorophenyl)-2-[4-(4-fluorobenzyl)piperidin-1-yl]ethanol 1
                                            (R)-eliprodil 1
                                              eliprodil 1
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