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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:eliprodil
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Accession:CHEBI:91784 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-eliprodil. It is a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist and an anti-ischaemic agent that exhibits neuroprotective properties.
Synonyms:exact_synonym: rac-1-(4-chlorophenyl)-2-[4-(4-fluorobenzyl)piperidin-1-yl]ethanol
 related_synonym: (+-)-alpha-(p-chlorophenyl)-4-(p-fluorobenzyl)-1-piperidineethanol;   (RS)-eliprodil;   Formula=C20H23ClFNO;   SL-82,0715;   SL-820715;   SL820715;   eliprodilum;   rac-1-(4-chlorophenyl)-2-{4-[(4-fluorophenyl)methyl]piperidin-1-yl}ethan-1-ol;   racemic eliprodil
 xref: CAS:119431-25-3;   Chemspider:54708;   DrugBank:DB12869;   HMDB:HMDB0251748;   LINCS:LSM-1677
 xref_mesh: MESH:C058083
 xref: PMID:10235550;   PMID:10235551;   PMID:10890168;   PMID:1354073;   PMID:15064913;   PMID:15302678;   PMID:24134630;   PMID:2849668;   PMID:29191857;   PMID:7814824;   PMID:8088348;   PMID:8402196;   PMID:8545484;   PMID:8719234;   PMID:8901012;   PMID:9089691;   PMID:9128850;   PMID:9369990;   PMID:9439799;   PMID:9519265;   PMID:9674557;   PMID:9718264;   PMID:9874159;   PMID:9932955;   Patent:EP0718407;   Wikipedia:Eliprodil



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eliprodil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO eliprodil inhibits the reaction [KCNH2 protein results in increased transport of Thallium] CTD PMID:19583963 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19757
    chemical entity 19755
      chemical substance 14004
        mixture 13298
          racemate 11728
            eliprodil 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19757
    subatomic particle 19755
      composite particle 19755
        hadron 19755
          baryon 19755
            nucleon 19755
              atomic nucleus 19755
                atom 19755
                  main group element atom 19703
                    main group molecular entity 19703
                      s-block molecular entity 19557
                        hydrogen molecular entity 19550
                          hydrides 19031
                            inorganic hydride 17955
                              pnictogen hydride 17940
                                nitrogen hydride 17836
                                  azane 17618
                                    ammonia 17617
                                      organic amino compound 17617
                                        tertiary amino compound 9929
                                          1-(4-chlorophenyl)-2-[4-(4-fluorobenzyl)piperidin-1-yl]ethanol 1
                                            (R)-eliprodil 1
                                              eliprodil 1
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