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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:eliprodil
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Accession:CHEBI:91784 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-eliprodil. It is a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist and an anti-ischaemic agent that exhibits neuroprotective properties.
Synonyms:exact_synonym: rac-1-(4-chlorophenyl)-2-[4-(4-fluorobenzyl)piperidin-1-yl]ethanol
 related_synonym: (+-)-alpha-(p-chlorophenyl)-4-(p-fluorobenzyl)-1-piperidineethanol;   (RS)-eliprodil;   Formula=C20H23ClFNO;   SL-82,0715;   SL-820715;   SL820715;   eliprodilum;   rac-1-(4-chlorophenyl)-2-{4-[(4-fluorophenyl)methyl]piperidin-1-yl}ethan-1-ol;   racemic eliprodil
 xref: CAS:119431-25-3;   Chemspider:54708;   DrugBank:DB12869;   HMDB:HMDB0251748;   LINCS:LSM-1677
 xref_mesh: MESH:C058083
 xref: PMID:10235550;   PMID:10235551;   PMID:10890168;   PMID:1354073;   PMID:15064913;   PMID:15302678;   PMID:24134630;   PMID:2849668;   PMID:29191857;   PMID:7814824;   PMID:8088348;   PMID:8402196;   PMID:8545484;   PMID:8719234;   PMID:8901012;   PMID:9089691;   PMID:9128850;   PMID:9369990;   PMID:9439799;   PMID:9519265;   PMID:9674557;   PMID:9718264;   PMID:9874159;   PMID:9932955;   Patent:EP0718407;   Wikipedia:Eliprodil



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eliprodil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO eliprodil inhibits the reaction [KCNH2 protein results in increased transport of Thallium] CTD PMID:19583963 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19795
    chemical entity 19795
      chemical substance 13189
        mixture 12396
          racemate 10479
            eliprodil 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19795
    subatomic particle 19794
      composite particle 19794
        hadron 19794
          baryon 19794
            nucleon 19794
              atomic nucleus 19794
                atom 19794
                  main group element atom 19693
                    main group molecular entity 19693
                      s-block molecular entity 19474
                        hydrogen molecular entity 19466
                          hydrides 18830
                            inorganic hydride 17688
                              pnictogen hydride 17668
                                nitrogen hydride 17540
                                  azane 17273
                                    ammonia 17272
                                      organic amino compound 17272
                                        tertiary amino compound 8695
                                          1-(4-chlorophenyl)-2-[4-(4-fluorobenzyl)piperidin-1-yl]ethanol 1
                                            (R)-eliprodil 1
                                              eliprodil 1
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