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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:eliprodil
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Accession:CHEBI:91784 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-eliprodil. It is a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist and an anti-ischaemic agent that exhibits neuroprotective properties.
Synonyms:exact_synonym: rac-1-(4-chlorophenyl)-2-[4-(4-fluorobenzyl)piperidin-1-yl]ethanol
 related_synonym: (+-)-alpha-(p-chlorophenyl)-4-(p-fluorobenzyl)-1-piperidineethanol;   (RS)-eliprodil;   Formula=C20H23ClFNO;   SL-82,0715;   SL-820715;   SL820715;   eliprodilum;   rac-1-(4-chlorophenyl)-2-{4-[(4-fluorophenyl)methyl]piperidin-1-yl}ethan-1-ol;   racemic eliprodil
 xref: CAS:119431-25-3;   Chemspider:54708;   DrugBank:DB12869;   HMDB:HMDB0251748;   LINCS:LSM-1677
 xref_mesh: MESH:C058083
 xref: PMID:10235550;   PMID:10235551;   PMID:10890168;   PMID:1354073;   PMID:15064913;   PMID:15302678;   PMID:24134630;   PMID:2849668;   PMID:29191857;   PMID:7814824;   PMID:8088348;   PMID:8402196;   PMID:8545484;   PMID:8719234;   PMID:8901012;   PMID:9089691;   PMID:9128850;   PMID:9369990;   PMID:9439799;   PMID:9519265;   PMID:9674557;   PMID:9718264;   PMID:9874159;   PMID:9932955;   Patent:EP0718407;   Wikipedia:Eliprodil



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eliprodil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO eliprodil inhibits the reaction [KCNH2 protein results in increased transport of Thallium] CTD PMID:19583963 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19803
    chemical entity 19830
      chemical substance 14400
        mixture 13718
          racemate 12092
            eliprodil 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19803
    subatomic particle 19801
      composite particle 19801
        hadron 19830
          baryon 19830
            nucleon 19830
              atomic nucleus 19830
                atom 19801
                  main group element atom 19780
                    main group molecular entity 19780
                      s-block molecular entity 19619
                        hydrogen molecular entity 19606
                          hydrides 19104
                            inorganic hydride 18112
                              pnictogen hydride 18077
                                nitrogen hydride 18008
                                  azane 17818
                                    ammonia 17817
                                      organic amino compound 17793
                                        tertiary amino compound 10127
                                          1-(4-chlorophenyl)-2-[4-(4-fluorobenzyl)piperidin-1-yl]ethanol 1
                                            (R)-eliprodil 1
                                              eliprodil 1
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