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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:myricetin
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Accession:CHEBI:18152 term browser browse the term
Definition:A hexahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 3', 4', 5, 5' and 7. It has been isolated from the leaves of Myrica rubra and other plants.
Synonyms:exact_synonym: 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one
 related_synonym: 3,3',4',5,5',7-Hexahydroxyflavone;   Cannabiscetin;   Formula=C15H10O8;   InChI=1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H;   InChIKey=IKMDFBPHZNJCSN-UHFFFAOYSA-N;   Myricetol;   SMILES=Oc1cc(O)c2c(c1)oc(-c1cc(O)c(O)c(O)c1)c(O)c2=O
 alt_id: CHEBI:14636;   CHEBI:44341;   CHEBI:7053
 xref: Beilstein:332331;   CAS:529-44-2;   DrugBank:DB02375;   HMDB:HMDB0002755;   KEGG:C10107;   KNApSAcK:C00001071;   LINCS:LSM-2957;   LIPID_MAPS_instance:LMPK12110001
 xref_mesh: MESH:C040015
 xref: MetaCyc:MYRICETIN;   PDBeChem:MYC;   PMID:19407970;   PMID:19778600;   PMID:22482362;   PMID:23099505;   PMID:23232835;   PMID:23265454;   PMID:23736695;   Reaxys:332331;   Wikipedia:Myricetin
 cyclic_relationship: is_conjugate_acid_of CHEBI:58395


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myricetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
multiple interactions
increases activity		 ISO myricetin results in increased expression of ABCB1 protein
myricetin inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]
myricetin results in increased activity of ABCB1 protein		 CTD PMID:34217736 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity
multiple interactions		 ISO myricetin results in decreased activity of ABCC1 protein
myricetin inhibits the reaction [ABCC1 protein affects the export of and results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC1 protein affects the export of Vincristine]; myricetin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC1 protein results in increased uptake of Leukotriene C4]		 CTD PMID:11306701 PMID:15670588 PMID:15896345 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
decreases activity		 ISO myricetin inhibits the reaction [ABCC2 protein affects the export of and results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC2 protein affects the export of Vincristine]; myricetin inhibits the reaction [ABCC2 protein results in decreased susceptibility to Vincristine]
myricetin results in decreased activity of ABCC2 protein		 CTD PMID:15670588 PMID:15896345 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Afp alpha-fetoprotein affects binding EXP myricetin binds to AFP protein CTD PMID:23013281 PMID:25349334 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Alb albumin multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of ALB protein] CTD PMID:24923654 PMID:25240712 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases cleavage ISO myricetin results in increased cleavage of ARHGDIB protein CTD PMID:15748703 NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658 		JBrowse link
G Atr ATR serine/threonine kinase multiple interactions ISO myricetin affects the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of ATR mRNA] CTD PMID:32342131 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
multiple interactions		 ISO myricetin results in decreased expression of BAX protein
Tetradecanoylphorbol Acetate inhibits the reaction [myricetin results in decreased expression of BAX protein]		 CTD PMID:15748703 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions		 ISO myricetin results in decreased expression of BCL2 protein
Tetradecanoylphorbol Acetate inhibits the reaction [myricetin results in decreased expression of BCL2 protein]		 CTD PMID:15748703 PMID:29698783 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage		 ISO myricetin results in increased activity of CASP3 protein
myricetin results in increased cleavage of CASP3 protein		 CTD PMID:15748703 PMID:19397994 PMID:29698783 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 decreases expression ISO myricetin results in decreased expression of CASP8 protein CTD PMID:29698783 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases activity
increases cleavage		 ISO myricetin results in increased activity of CASP9 protein
myricetin results in increased cleavage of CASP9 protein		 CTD PMID:15748703 PMID:29698783 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions ISO
EXP		 myricetin inhibits the reaction [Rotenone results in increased activity of CAT protein]
myricetin inhibits the reaction [Ethanol results in decreased activity of CAT protein]		 CTD PMID:15904944 PMID:35156864 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO myricetin results in decreased expression of CCNB1 mRNA; myricetin results in decreased expression of CCNB1 protein CTD PMID:19397994 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO myricetin results in increased expression of CDKN1A mRNA; myricetin results in increased expression of CDKN1A protein CTD PMID:19397994 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C increases expression ISO myricetin results in increased expression of CDKN2C mRNA CTD PMID:18331776 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278 		JBrowse link
G Cfl1 cofilin 1 increases expression ISO myricetin results in increased expression of CFL1 protein CTD PMID:29698783 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Cldn1 claudin 1 multiple interactions EXP myricetin inhibits the reaction [Indomethacin results in decreased expression of CLDN1 mRNA]; myricetin inhibits the reaction [Indomethacin results in decreased expression of CLDN1 protein] CTD PMID:33276066 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724 		JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [myricetin co-treated with COMT protein] results in decreased activity of DNMT1 protein CTD PMID:16037419 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Cox5b cytochrome c oxidase subunit 5B increases expression ISO myricetin results in increased expression of COX5B protein CTD PMID:29698783 NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052 		JBrowse link
G Ctnnb1 catenin beta 1 decreases expression
multiple interactions		 ISO myricetin results in decreased expression of CTNNB1 protein
[myricetin results in increased activity of SIRT1 protein] which results in decreased expression of CTNNB1 protein		 CTD PMID:22245592 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cycs cytochrome c, somatic affects localization
multiple interactions		 ISO myricetin affects the localization of CYCS protein
Tetradecanoylphorbol Acetate inhibits the reaction [myricetin affects the localization of CYCS protein]		 CTD PMID:15748703 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO myricetin promotes the reaction [Cyclic AMP results in increased expression of CYP11A1 mRNA] CTD PMID:28668616 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
increases expression
multiple interactions		 ISO myricetin results in decreased activity of CYP1A1 protein
myricetin results in increased expression of CYP1A1 mRNA
myricetin inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]		 CTD PMID:16271822 PMID:20930378 PMID:21482471 PMID:29584932 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO myricetin results in decreased activity of CYP1A2 protein CTD PMID:29753067 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO myricetin results in decreased activity of CYP1B1 protein CTD PMID:16271822 PMID:21482471 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases activity ISO myricetin results in decreased activity of CYP2C19 protein CTD PMID:29753067 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO myricetin results in decreased activity of CYP2D6 protein CTD PMID:29753067 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO myricetin results in decreased activity of CYP2E1 protein CTD PMID:29753067 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO myricetin results in decreased activity of CYP3A4 protein CTD PMID:29753067 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions
decreases activity		 ISO [myricetin co-treated with COMT protein] results in decreased activity of DNMT1 protein
myricetin results in decreased activity of DNMT1 protein		 CTD PMID:16037419 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO myricetin inhibits the reaction [EGF protein results in increased expression of FOS mRNA]; myricetin inhibits the reaction [EGF protein results in increased expression of STAT3 mRNA]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of JAK1 protein]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK9 protein]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KA1 protein]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]; myricetin promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:17693661 PMID:18995957 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
decreases phosphorylation		 ISO myricetin promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein]
myricetin results in decreased phosphorylation of EGFR protein		 CTD PMID:18995957 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 decreases expression
multiple interactions		 ISO myricetin results in decreased expression of EGLN1 protein
[myricetin results in increased activity of SIRT1 protein] which results in decreased expression of EGLN1 protein		 CTD PMID:22245592 NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777 		JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO myricetin promotes the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]] CTD PMID:20153296 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Fbp1 fructose-bisphosphatase 1 decreases expression ISO myricetin results in decreased expression of FBP1 mRNA CTD PMID:18331776 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071 		JBrowse link
G Fdx1 ferredoxin 1 multiple interactions ISO myricetin promotes the reaction [Cyclic AMP results in increased expression of FDX1 mRNA] CTD PMID:28668616 NCBI chr 8:52,268,536...52,287,344
Ensembl chr 8:52,268,536...52,287,414 		JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of FN1 protein] CTD PMID:25240712 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO myricetin inhibits the reaction [EGF protein results in increased expression of FOS mRNA]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA] CTD PMID:17693661 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein] CTD PMID:24923654 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP myricetin inhibits the reaction [Ethanol results in increased activity of GPT protein] CTD PMID:35156864 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP myricetin inhibits the reaction [Ethanol results in decreased activity of GSR protein] CTD PMID:35156864 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO myricetin inhibits the reaction [Doxorubicin results in increased expression of H2AX protein] CTD PMID:32107588 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO myricetin affects the reaction [Sodium Chloride results in increased expression of HBEGF mRNA] CTD PMID:26800359 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Hgf hepatocyte growth factor multiple interactions ISO myricetin inhibits the reaction [HGF protein results in increased phosphorylation of MET protein] CTD PMID:19244381 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
decreases activity
multiple interactions		 ISO myricetin results in increased expression of HIF1A protein
myricetin results in decreased activity of HIF1A protein
[myricetin results in increased activity of SIRT1 protein] which results in increased expression of HIF1A protein; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HIF1A mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HIF1A protein]]; myricetin inhibits the reaction [Formaldehyde results in increased expression of HIF1A mRNA]; myricetin inhibits the reaction [Formaldehyde results in increased expression of HIF1A protein]; myricetin promotes the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]		 CTD PMID:19958256 PMID:20153296 PMID:22245592 PMID:36116563 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hk2 hexokinase 2 multiple interactions ISO Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HK2 mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HK2 protein]]; myricetin inhibits the reaction [Formaldehyde results in increased expression of HK2 mRNA]; myricetin inhibits the reaction [Formaldehyde results in increased expression of HK2 protein] CTD PMID:36116563 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased activity of HMGCR protein] CTD PMID:25240712 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO myricetin results in increased expression of HMOX1 protein CTD PMID:16799064 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hras HRas proto-oncogene, GTPase decreases activity ISO myricetin results in decreased activity of HRAS protein CTD PMID:17693661 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP		 myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]
myricetin inhibits the reaction [Ethanol results in increased expression of IL6 protein]		 CTD PMID:18958421 PMID:35156864 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ins1 insulin 1 multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of INS1 protein] CTD PMID:24923654 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of IRS1 protein] CTD PMID:24923654 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of IRS2 protein] CTD PMID:24923654 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482 		JBrowse link
G Jak1 Janus kinase 1 affects binding
multiple interactions		 ISO myricetin binds to JAK1 protein
myricetin inhibits the reaction [EGF protein results in increased phosphorylation of JAK1 protein]		 CTD PMID:18995957 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Lcat lecithin cholesterol acyltransferase multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of LCAT protein] CTD PMID:25240712 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231 		JBrowse link
G Ldha lactate dehydrogenase A multiple interactions ISO Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of LDHA mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of LDHA protein]]; myricetin inhibits the reaction [Formaldehyde results in increased expression of LDHA mRNA]; myricetin inhibits the reaction [Formaldehyde results in increased expression of LDHA protein] CTD PMID:36116563 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472 		JBrowse link
G Lpl lipoprotein lipase multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of LPL protein] CTD PMID:25240712 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Ltf lactotransferrin increases expression EXP myricetin results in increased expression of LTF protein CTD PMID:24487097 NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795 		JBrowse link
G Ltn1 listerin E3 ubiquitin protein ligase 1 decreases expression ISO myricetin results in decreased expression of LTN1 protein CTD PMID:29698783 NCBI chr11:26,603,903...26,660,871
Ensembl chr11:26,603,903...26,660,886 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions ISO myricetin binds to and results in decreased activity of MAP2K1 protein; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAP2K1 protein] CTD PMID:17693661 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 decreases phosphorylation ISO Myricetin decreases phosphorylation of Map3k7 protein in the heart RGD PMID:31885808 RGD:155791644 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases activity		 ISO myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]
myricetin results in decreased activity of MAPK1 protein		 CTD PMID:17693661 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein] CTD PMID:17693661 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK9 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein] CTD PMID:17693661 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase multiple interactions ISO myricetin inhibits the reaction [HGF protein results in increased phosphorylation of MET protein] CTD PMID:19244381 NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein] CTD PMID:19804834 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
multiple interactions		 ISO myricetin results in decreased expression of MYC protein
[myricetin results in increased activity of SIRT1 protein] which results in decreased expression of MYC protein		 CTD PMID:22245592 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression ISO myricetin results in increased expression of NFE2L2 protein CTD PMID:16799064 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 increases expression ISO myricetin results in increased expression of NME1 protein CTD PMID:29698783 NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408 		JBrowse link
G Ocln occludin multiple interactions EXP myricetin inhibits the reaction [Indomethacin results in decreased expression of OCLN mRNA]; myricetin inhibits the reaction [Indomethacin results in decreased expression of OCLN protein] CTD PMID:33276066 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Parg poly (ADP-ribose) glycohydrolase decreases activity ISO myricetin results in decreased activity of PARG protein CTD PMID:19840838 NCBI chr16:7,436,429...7,544,276
Ensembl chr16:7,436,476...7,544,273 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
decreases activity		 ISO myricetin results in increased cleavage of PARP1 protein
myricetin results in decreased activity of PARP1 protein		 CTD PMID:15748703 PMID:17884996 PMID:29698783 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pik3c2b phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta decreases expression ISO myricetin results in decreased expression of PIK3C2B protein CTD PMID:29698783 NCBI chr13:44,494,673...44,555,663
Ensembl chr13:44,495,050...44,555,612 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of PPARA protein] CTD PMID:25240712 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Psca prostate stem cell antigen decreases expression ISO myricetin results in decreased expression of PSCA mRNA CTD PMID:18331776 NCBI chr 7:106,598,203...106,603,114
Ensembl chr 7:106,595,284...106,609,746 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]		 CTD PMID:17944529 PMID:19804834 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of and results in increased activity of RELA protein] CTD PMID:18958421 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rps12 ribosomal protein S12 decreases expression ISO myricetin results in decreased expression of RPS12 protein CTD PMID:29698783 NCBI chr 1:21,680,854...21,683,010
Ensembl chr 1:21,680,852...21,683,014 		JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 multiple interactions ISO myricetin inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KA1 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KA1 protein] CTD PMID:17693661 NCBI chr 5:146,079,018...146,118,272
Ensembl chr 5:146,079,021...146,118,272 		JBrowse link
G Rps6kb2 ribosomal protein S6 kinase B2 increases expression ISO myricetin results in increased expression of RPS6KB2 protein CTD PMID:29698783 NCBI chr 1:201,451,265...201,458,096
Ensembl chr 1:201,451,265...201,458,078 		JBrowse link
G Sirt1 sirtuin 1 increases activity
increases expression
multiple interactions		 ISO myricetin results in increased activity of SIRT1 protein
myricetin results in increased expression of SIRT1 protein
[myricetin results in increased activity of SIRT1 protein] which results in decreased expression of CTNNB1 protein; [myricetin results in increased activity of SIRT1 protein] which results in decreased expression of EGLN1 protein; [myricetin results in increased activity of SIRT1 protein] which results in decreased expression of MYC protein; [myricetin results in increased activity of SIRT1 protein] which results in increased expression of HIF1A protein		 CTD PMID:22245592 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions
decreases activity		 ISO Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 protein]]; myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 mRNA]; myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 protein]; myricetin inhibits the reaction [SLC2A1 protein affects the transport of Glucose]
myricetin results in decreased activity of SLC2A1 protein		 CTD PMID:14642735 PMID:36116563 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of SLC2A2 protein] CTD PMID:24923654 NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions EXP myricetin inhibits the reaction [Indomethacin results in increased phosphorylation of SRC protein] CTD PMID:33276066 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF1 protein] CTD PMID:25240712 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF2 protein] CTD PMID:25240712 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848 		JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO myricetin promotes the reaction [Cyclic AMP results in increased expression of STAR mRNA] CTD PMID:28668616 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO myricetin inhibits the reaction [EGF protein results in increased expression of STAT3 mRNA]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein] CTD PMID:18995957 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stk38l serine/threonine kinase 38 like decreases expression ISO myricetin results in decreased expression of STK38L protein CTD PMID:29698783 NCBI chr 4:179,616,288...179,693,177
Ensembl chr 4:179,634,275...179,690,983 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of TGFB1 protein] CTD PMID:25240712 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tjp1 tight junction protein 1 multiple interactions EXP myricetin inhibits the reaction [Indomethacin results in decreased expression of TJP1 mRNA]; myricetin inhibits the reaction [Indomethacin results in decreased expression of TJP1 protein] CTD PMID:33276066 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP		 myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]
myricetin inhibits the reaction [Ethanol results in increased expression of TNF protein]		 CTD PMID:18958421 PMID:35156864 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Top2a DNA topoisomerase II alpha decreases activity ISO myricetin results in decreased activity of TOP2A protein CTD PMID:16536579 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874 		JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions		 ISO myricetin analog results in increased expression of TP53 mRNA; myricetin analog results in increased expression of TP53 protein; myricetin results in increased expression of TP53 protein
myricetin affects the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of TP53 mRNA]		 CTD PMID:32220605 PMID:32342131 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 increases expression ISO myricetin results in increased expression of TP53I3 mRNA; myricetin results in increased expression of TP53I3 protein CTD PMID:19397994 NCBI chr 6:27,818,327...27,825,753 JBrowse link
G Tp63 tumor protein p63 increases expression ISO myricetin results in increased expression of TP63 protein CTD PMID:19397994 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
G Tp73 tumor protein p73 increases expression ISO myricetin results in increased expression of TP73 protein CTD PMID:19397994 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases activity
multiple interactions		 EXP myricetin results in decreased activity of TXNRD1 protein modified form
[Xanthine co-treated with XDH protein] promotes the reaction [myricetin results in decreased activity of TXNRD1 protein modified form]; Nitrogen inhibits the reaction [myricetin results in decreased activity of TXNRD1 protein modified form]		 CTD PMID:16618767 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 decreases activity ISO myricetin results in decreased activity of UGT1A1 protein CTD PMID:35063619 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 decreases activity ISO myricetin results in decreased activity of UGT1A3 protein CTD PMID:35063619 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 decreases activity ISO myricetin results in decreased activity of UGT1A6 protein CTD PMID:35063619 NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 decreases activity ISO myricetin results in decreased activity of UGT1A9 protein CTD PMID:35063619 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 decreases activity ISO myricetin results in decreased activity of UGT2B7 protein CTD PMID:35063619 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP
ISO		 myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of VEGFA protein]
myricetin inhibits the reaction [cobaltous chloride results in increased expression of VEGFA mRNA]; myricetin promotes the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]		 CTD PMID:20153296 PMID:25240712 PMID:26800359 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Xdh xanthine dehydrogenase multiple interactions EXP [Xanthine co-treated with XDH protein] promotes the reaction [myricetin results in decreased activity of TXNRD1 protein modified form]; myricetin inhibits the reaction [Ethanol results in increased activity of XDH protein] CTD PMID:16618767 PMID:35156864 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268 		JBrowse link
(+)-dihydromyricetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK1 protein] CTD PMID:21871475 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK3 protein] CTD PMID:21871475 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions EXP ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK1 protein]; ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK3 protein]; ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PDGFRB protein]; ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PLCG1 protein] CTD PMID:21871475 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions EXP ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PDGFRB protein] CTD PMID:21871475 NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Plcg1 phospholipase C, gamma 1 multiple interactions EXP ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PLCG1 protein] CTD PMID:21871475 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330 		JBrowse link
G Sphk1 sphingosine kinase 1 decreases expression
decreases activity		 ISO ampelopsin results in decreased expression of SPHK1 protein
ampelopsin results in decreased activity of SPHK1 protein		 CTD PMID:22251058 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
myricitrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:25656916 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ALPL mRNA] CTD PMID:25130202 NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446 		JBrowse link
G Apoe apolipoprotein E multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in decreased activity of CAT protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased activity of CASP3 protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CCL2 protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CRP protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of ICAM1 protein] CTD PMID:23639522 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein] CTD PMID:23639522 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:23639522 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BGLAP mRNA] CTD PMID:25130202 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]
myricitrin inhibits the reaction [APOE gene mutant form results in increased activity of CASP3 protein]		 CTD PMID:23639522 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein]
myricitrin inhibits the reaction [APOE gene mutant form results in decreased activity of CAT protein]		 CTD PMID:23639522 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CCL2 protein] CTD PMID:23639522 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of COL1A1 mRNA] CTD PMID:25130202 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Crp C-reactive protein multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CRP protein] CTD PMID:23639522 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein] CTD PMID:25656916 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein] CTD PMID:25656916 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of GPX1 protein] CTD PMID:23639522 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of ICAM1 protein] CTD PMID:23639522 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of IL6 protein] CTD PMID:25130202 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein] CTD PMID:23639522 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein] CTD PMID:23639522 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:23639522 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of NOS3 protein] CTD PMID:23639522 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO myricitrin promotes the reaction [Carbon Tetrachloride results in increased expression of PCNA protein] CTD PMID:25656916 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of PPARG mRNA] CTD PMID:25130202 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein] CTD PMID:25656916 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein] CTD PMID:25656916 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein] CTD PMID:25656916 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFSF11 protein] CTD PMID:25130202 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein] CTD PMID:23639522 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19900
    role 19875
      chemical role 19497
        antioxidant 16054
          myricetin 124
            3',5,7-trihydroxy-3,4',5'-trimethoxyflavone 0
            3',5-dihydroxy-3,4',5',7-tetramethoxyflavone 0
            3,3',4',5'-tetramethylmyricetin 0
            3,3',5'-trimethylmyricetin 0
            5,7,3',5'-tetrahydroxy-3,4'-dimethyoxyflavone 0
            7,3',5'-trimethylmyricetin 0
            7-O-methylmyricetin 0
            combretol 0
            dihydromyricetin + 6
            laricitrin 0
            myricetin 3-O-[(6-O-trans-4-coumaroyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside] 0
            myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] + 0
            myricetin 3-O-beta-D-galactopyranoside 0
            myricetin 3-O-beta-L-galactopyranoside 0
            myricetin O-glucoside + 0
            myricetin O-glucuronide + 0
            myricetin-3-O-arabinofuranoside 0
            myricetin-3-O-beta-D-xylopyranoside 0
            myricitrin + 27
            syringetin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19900
    subatomic particle 19898
      composite particle 19898
        hadron 19898
          baryon 19898
            nucleon 19898
              atomic nucleus 19898
                atom 19898
                  main group element atom 19845
                    p-block element atom 19845
                      carbon group element atom 19792
                        carbon atom 19787
                          organic molecular entity 19787
                            organic molecule 19744
                              organic cyclic compound 19549
                                organic heterocyclic compound 18888
                                  oxacycle 17807
                                    benzopyran 11743
                                      1-benzopyran 11507
                                        flavonoid 6842
                                          anthoxanthin 4530
                                            flavones 4530
                                              hydroxyflavone 4510
                                                flavonols 4404
                                                  7-hydroxyflavonol 4381
                                                    myricetin 124
                                                      3',5,7-trihydroxy-3,4',5'-trimethoxyflavone 0
                                                      3',5-dihydroxy-3,4',5',7-tetramethoxyflavone 0
                                                      3,3',4',5'-tetramethylmyricetin 0
                                                      3,3',5'-trimethylmyricetin 0
                                                      5,7,3',5'-tetrahydroxy-3,4'-dimethyoxyflavone 0
                                                      7,3',5'-trimethylmyricetin 0
                                                      7-O-methylmyricetin 0
                                                      combretol 0
                                                      dihydromyricetin + 6
                                                      laricitrin 0
                                                      myricetin 3-O-[(6-O-trans-4-coumaroyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside] 0
                                                      myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] + 0
                                                      myricetin 3-O-beta-D-galactopyranoside 0
                                                      myricetin 3-O-beta-L-galactopyranoside 0
                                                      myricetin O-glucoside + 0
                                                      myricetin O-glucuronide + 0
                                                      myricetin-3-O-arabinofuranoside 0
                                                      myricetin-3-O-beta-D-xylopyranoside 0
                                                      myricitrin + 27
                                                      syringetin 0
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