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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:myricetin
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Accession:CHEBI:18152 term browser browse the term
Definition:A hexahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 3', 4', 5, 5' and 7. It has been isolated from the leaves of Myrica rubra and other plants.
Synonyms:exact_synonym: 3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one
 related_synonym: 3,3',4',5,5',7-Hexahydroxyflavone;   Cannabiscetin;   Formula=C15H10O8;   InChI=1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H;   InChIKey=IKMDFBPHZNJCSN-UHFFFAOYSA-N;   Myricetol;   SMILES=Oc1cc(O)c2c(c1)oc(-c1cc(O)c(O)c(O)c1)c(O)c2=O
 alt_id: CHEBI:14636;   CHEBI:44341;   CHEBI:7053
 xref: CAS:529-44-2;   DrugBank:DB02375;   HMDB:HMDB0002755;   KEGG:C10107;   KNApSAcK:C00001071;   LINCS:LSM-2957;   LIPID_MAPS_instance:LMPK12110001
 xref_mesh: MESH:C040015
 xref: MetaCyc:MYRICETIN;   PDBeChem:MYC;   PMID:19407970;   PMID:19778600;   PMID:22482362;   PMID:23099505;   PMID:23232835;   PMID:23265454;   PMID:23736695;   Reaxys:332331;   Wikipedia:Myricetin
 cyclic_relationship: is_conjugate_acid_of CHEBI:58395



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myricetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
multiple interactions
increases activity
ISO myricetin results in increased expression of ABCB1 protein
myricetin inhibits the reaction [ABCB1 protein results in decreased uptake of Rhodamine 123]
myricetin results in increased activity of ABCB1 protein
CTD PMID:34217736 NCBI chr 4:26,312,403...26,488,456
Ensembl chr 4:26,312,409...26,397,135
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity
multiple interactions
ISO myricetin results in decreased activity of ABCC1 protein
myricetin inhibits the reaction [ABCC1 protein affects the export of and results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC1 protein affects the export of Vincristine]; myricetin inhibits the reaction [ABCC1 protein results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC1 protein results in increased uptake of Leukotriene C4]
CTD PMID:11306701 PMID:15670588 PMID:15896345 NCBI chr10:1,022,041...1,162,431
Ensembl chr10:1,038,947...1,162,404
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
decreases activity
ISO myricetin inhibits the reaction [ABCC2 protein affects the export of and results in decreased susceptibility to Vincristine]; myricetin inhibits the reaction [ABCC2 protein affects the export of Vincristine]; myricetin inhibits the reaction [ABCC2 protein results in decreased susceptibility to Vincristine]
myricetin results in decreased activity of ABCC2 protein
CTD PMID:15670588 PMID:15896345 NCBI chr 1:252,613,875...252,672,459
Ensembl chr 1:252,614,017...252,673,471
JBrowse link
G Afp alpha-fetoprotein affects binding EXP myricetin binds to AFP protein CTD PMID:23013281 PMID:25349334 NCBI chr14:17,857,584...17,875,645
Ensembl chr14:17,857,584...17,875,649
JBrowse link
G Akr1b15 aldo-keto reductase family 1 member B15 decreases activity EXP myricetin results in decreased activity of AKR1B8 protein CTD PMID:18845131 NCBI chr 4:63,964,421...63,976,995
Ensembl chr 4:63,960,880...63,978,349
JBrowse link
G Alb albumin multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of ALB protein] CTD PMID:24923654 PMID:25240712 NCBI chr14:17,891,564...17,907,043
Ensembl chr14:17,891,582...17,911,865
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases cleavage ISO myricetin results in increased cleavage of ARHGDIB protein CTD PMID:15748703 NCBI chr 4:171,554,139...171,573,057
Ensembl chr 4:171,554,140...171,573,068
JBrowse link
G Atr ATR serine/threonine kinase multiple interactions ISO myricetin affects the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of ATR mRNA] CTD PMID:32342131 NCBI chr 8:105,306,299...105,403,742
Ensembl chr 8:105,306,305...105,403,718
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
multiple interactions
ISO myricetin results in decreased expression of BAX protein
Tetradecanoylphorbol Acetate inhibits the reaction [myricetin results in decreased expression of BAX protein]
CTD PMID:15748703 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
ISO myricetin results in decreased expression of BCL2 protein
Tetradecanoylphorbol Acetate inhibits the reaction [myricetin results in decreased expression of BCL2 protein]
CTD PMID:15748703 PMID:29698783 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage
ISO myricetin results in increased activity of CASP3 protein
myricetin results in increased cleavage of CASP3 protein
CTD PMID:15748703 PMID:19397994 PMID:29698783 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Casp8 caspase 8 decreases expression ISO myricetin results in decreased expression of CASP8 protein CTD PMID:29698783 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:67,758,033...67,806,699
JBrowse link
G Casp9 caspase 9 increases activity
increases cleavage
ISO myricetin results in increased activity of CASP9 protein
myricetin results in increased cleavage of CASP9 protein
CTD PMID:15748703 PMID:29698783 Ensembl chr 5:159,391,188...159,409,648 JBrowse link
G Cat catalase multiple interactions ISO
EXP
myricetin inhibits the reaction [Rotenone results in increased activity of CAT protein]
myricetin inhibits the reaction [Ethanol results in decreased activity of CAT protein]
CTD PMID:15904944 PMID:35156864 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO myricetin results in decreased expression of CCNB1 mRNA; myricetin results in decreased expression of CCNB1 protein CTD PMID:19397994 NCBI chr 2:33,646,252...33,655,225
Ensembl chr 2:33,646,252...33,655,225
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO myricetin results in increased expression of CDKN1A mRNA; myricetin results in increased expression of CDKN1A protein CTD PMID:19397994 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,153,958...7,164,969
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C increases expression ISO myricetin results in increased expression of CDKN2C mRNA CTD PMID:18331776 NCBI chr 5:129,639,736...129,645,564
Ensembl chr 5:129,639,736...129,644,891
JBrowse link
G Cfl1 cofilin 1 increases expression ISO myricetin results in increased expression of CFL1 protein CTD PMID:29698783 NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:212,226,121...212,231,353
JBrowse link
G Cldn1 claudin 1 multiple interactions EXP myricetin inhibits the reaction [Indomethacin results in decreased expression of CLDN1 mRNA]; myricetin inhibits the reaction [Indomethacin results in decreased expression of CLDN1 protein] CTD PMID:33276066 NCBI chr11:87,926,376...87,941,533
Ensembl chr11:87,926,337...87,941,529
JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [myricetin co-treated with COMT protein] results in decreased activity of DNMT1 protein CTD PMID:16037419 NCBI chr11:96,072,371...96,091,956
Ensembl chr11:96,072,489...96,092,533
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B increases expression ISO myricetin results in increased expression of COX5B protein CTD PMID:29698783 NCBI chr 9:46,417,735...46,419,664
Ensembl chr 9:46,417,838...46,420,403
JBrowse link
G Ctnnb1 catenin beta 1 decreases expression
multiple interactions
ISO myricetin results in decreased expression of CTNNB1 protein
[myricetin results in increased activity of SIRT1 protein] which results in decreased expression of CTNNB1 protein
CTD PMID:22245592 NCBI chr 8:129,517,576...129,544,661
Ensembl chr 8:129,517,545...129,544,662
JBrowse link
G Cycs cytochrome c, somatic affects localization
multiple interactions
ISO myricetin affects the localization of CYCS protein
Tetradecanoylphorbol Acetate inhibits the reaction [myricetin affects the localization of CYCS protein]
CTD PMID:15748703 NCBI chr 4:80,982,667...80,984,767
Ensembl chr 4:80,982,668...80,984,816
Ensembl chr18:80,982,668...80,984,816
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions ISO myricetin promotes the reaction [Cyclic AMP results in increased expression of CYP11A1 mRNA] CTD PMID:28668616 NCBI chr 8:67,318,665...67,330,196
Ensembl chr 8:67,270,556...67,330,196
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
increases expression
multiple interactions
ISO myricetin results in decreased activity of CYP1A1 protein
myricetin results in increased expression of CYP1A1 mRNA
myricetin inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]
CTD PMID:16271822 PMID:20930378 PMID:21482471 PMID:29584932 NCBI chr 8:66,991,940...66,998,014
Ensembl chr 8:66,991,970...66,998,012
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO myricetin results in decreased activity of CYP1A2 protein CTD PMID:29753067 NCBI chr 8:66,971,261...66,978,149
Ensembl chr 8:66,971,261...66,978,149
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO myricetin results in decreased activity of CYP1B1 protein CTD PMID:16271822 PMID:21482471 NCBI chr 6:21,093,927...21,103,091
Ensembl chr 6:21,078,146...21,103,142
JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases activity ISO myricetin results in decreased activity of CYP2C19 protein CTD PMID:29753067 NCBI chr 1:247,879,058...247,916,804
Ensembl chr 1:247,879,078...247,916,798
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO myricetin results in decreased activity of CYP2D6 protein CTD PMID:29753067 NCBI chr 7:115,762,662...115,771,832
Ensembl chr 7:115,761,696...115,771,837
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO myricetin results in decreased activity of CYP2E1 protein CTD PMID:29753067 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO myricetin results in decreased activity of CYP3A4 protein CTD PMID:29753067 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:14,321,771...14,343,857
JBrowse link
G Dnmt1 DNA methyltransferase 1 multiple interactions
decreases activity
ISO [myricetin co-treated with COMT protein] results in decreased activity of DNMT1 protein
myricetin results in decreased activity of DNMT1 protein
CTD PMID:16037419 NCBI chr 8:27,716,797...27,763,405
Ensembl chr 8:27,716,797...27,763,119
JBrowse link
G Egf epidermal growth factor multiple interactions ISO myricetin inhibits the reaction [EGF protein results in increased expression of FOS mRNA]; myricetin inhibits the reaction [EGF protein results in increased expression of STAT3 mRNA]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of JAK1 protein]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK9 protein]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KA1 protein]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]; myricetin promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:17693661 PMID:18995957 NCBI chr 2:220,893,660...220,976,331
Ensembl chr 2:220,893,660...220,976,297
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions
decreases phosphorylation
ISO myricetin promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein]
myricetin results in decreased phosphorylation of EGFR protein
CTD PMID:18995957 NCBI chr14:95,378,626...95,551,358
Ensembl chr14:95,378,626...95,551,358
JBrowse link
G Egln1 egl-9 family hypoxia-inducible factor 1 decreases expression
multiple interactions
ISO myricetin results in decreased expression of EGLN1 protein
[myricetin results in increased activity of SIRT1 protein] which results in decreased expression of EGLN1 protein
CTD PMID:22245592 NCBI chr19:69,765,276...69,804,681 JBrowse link
G Ep300 E1A binding protein p300 multiple interactions ISO myricetin promotes the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]] CTD PMID:20153296 NCBI chr 7:114,987,857...115,058,652
Ensembl chr 7:114,946,982...115,058,574
JBrowse link
G Fbp1 fructose-bisphosphatase 1 decreases expression ISO myricetin results in decreased expression of FBP1 mRNA CTD PMID:18331776 NCBI chr17:2,212,941...2,235,749
Ensembl chr17:2,213,492...2,235,746
JBrowse link
G Fdx1 ferredoxin 1 multiple interactions ISO myricetin promotes the reaction [Cyclic AMP results in increased expression of FDX1 mRNA] CTD PMID:28668616 NCBI chr 8:61,164,839...61,183,645
Ensembl chr 8:61,164,839...61,183,583
JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of FN1 protein] CTD PMID:25240712 NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:80,645,507...80,714,137
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO myricetin inhibits the reaction [EGF protein results in increased expression of FOS mRNA]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of FOS mRNA] CTD PMID:17693661 NCBI chr 6:110,852,188...110,855,054
Ensembl chr 6:110,852,190...110,855,598
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of G6PD protein] CTD PMID:24923654 NCBI chr  X:157,352,364...157,372,144
Ensembl chr  X:157,352,373...157,372,144
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP myricetin inhibits the reaction [Ethanol results in increased activity of GPT protein] CTD PMID:35156864 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP myricetin inhibits the reaction [Ethanol results in decreased activity of GSR protein] CTD PMID:35156864 NCBI chr16:65,185,574...65,228,742
Ensembl chr16:65,185,574...65,228,394
JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO myricetin inhibits the reaction [Doxorubicin results in increased expression of H2AX protein] CTD PMID:32107588 NCBI chr 8:53,568,718...53,570,072
Ensembl chr 8:53,568,281...53,573,079
JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO myricetin affects the reaction [Sodium Chloride results in increased expression of HBEGF mRNA] CTD PMID:26800359 NCBI chr18:28,380,337...28,390,220
Ensembl chr18:28,380,337...28,390,220
JBrowse link
G Hgf hepatocyte growth factor multiple interactions ISO myricetin inhibits the reaction [HGF protein results in increased phosphorylation of MET protein] CTD PMID:19244381 NCBI chr 4:19,628,902...19,700,467
Ensembl chr 4:19,632,267...19,700,851
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
decreases activity
multiple interactions
ISO myricetin results in increased expression of HIF1A protein
myricetin results in decreased activity of HIF1A protein
[myricetin results in increased activity of SIRT1 protein] which results in increased expression of HIF1A protein; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HIF1A mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HIF1A protein]]; myricetin inhibits the reaction [Formaldehyde results in increased expression of HIF1A mRNA]; myricetin inhibits the reaction [Formaldehyde results in increased expression of HIF1A protein]; myricetin promotes the reaction [Oxygen deficiency promotes the reaction [HIF1A protein binds to EP300 protein]]
CTD PMID:19958256 PMID:20153296 PMID:22245592 PMID:36116563 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:98,359,910...98,405,323
JBrowse link
G Hk2 hexokinase 2 multiple interactions ISO Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HK2 mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of HK2 protein]]; myricetin inhibits the reaction [Formaldehyde results in increased expression of HK2 mRNA]; myricetin inhibits the reaction [Formaldehyde results in increased expression of HK2 protein] CTD PMID:36116563 NCBI chr 4:116,792,258...116,841,275
Ensembl chr 4:116,792,258...116,841,275
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased activity of HMGCR protein] CTD PMID:25240712 NCBI chr 2:29,732,163...29,754,276
Ensembl chr 2:29,720,553...29,754,533
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO myricetin results in increased expression of HMOX1 protein CTD PMID:16799064 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,472,884...13,479,818
JBrowse link
G Hras HRas proto-oncogene, GTPase decreases activity ISO myricetin results in decreased activity of HRAS protein CTD PMID:17693661 NCBI chr 1:205,712,625...205,729,406
Ensembl chr 1:205,725,975...205,729,590
JBrowse link
G Il6 interleukin 6 multiple interactions ISO
EXP
myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of IL6 protein]
myricetin inhibits the reaction [Ethanol results in increased expression of IL6 protein]
CTD PMID:18958421 PMID:35156864 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Ins1 insulin 1 multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of INS1 protein] CTD PMID:24923654 NCBI chr 1:261,186,119...261,186,686
Ensembl chr 1:261,186,119...261,186,682
JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of IRS1 protein] CTD PMID:24923654 NCBI chr 9:91,001,137...91,053,959
Ensembl chr 9:90,993,519...91,054,538
JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of IRS2 protein] CTD PMID:24923654 NCBI chr16:85,190,310...85,214,543
Ensembl chr16:85,190,111...85,214,543
JBrowse link
G Jak1 Janus kinase 1 affects binding
multiple interactions
ISO myricetin binds to JAK1 protein
myricetin inhibits the reaction [EGF protein results in increased phosphorylation of JAK1 protein]
CTD PMID:18995957 NCBI chr 5:120,895,606...121,004,207
Ensembl chr 5:120,896,046...120,996,758
JBrowse link
G Lcat lecithin cholesterol acyltransferase multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of LCAT protein] CTD PMID:25240712 NCBI chr19:50,744,598...50,748,064
Ensembl chr19:50,744,601...50,748,081
JBrowse link
G Ldha lactate dehydrogenase A multiple interactions ISO Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of LDHA mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of LDHA protein]]; myricetin inhibits the reaction [Formaldehyde results in increased expression of LDHA mRNA]; myricetin inhibits the reaction [Formaldehyde results in increased expression of LDHA protein] CTD PMID:36116563 NCBI chr 1:106,508,092...106,517,512
Ensembl chr 1:106,502,182...106,517,521
JBrowse link
G Lpl lipoprotein lipase multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased activity of LPL protein] CTD PMID:25240712 NCBI chr16:25,596,205...25,621,928
Ensembl chr16:25,596,211...25,622,107
JBrowse link
G Ltf lactotransferrin increases expression EXP myricetin results in increased expression of LTF protein CTD PMID:24487097 NCBI chr 8:119,878,344...119,901,189
Ensembl chr 8:119,878,344...119,901,189
JBrowse link
G Ltn1 listerin E3 ubiquitin protein ligase 1 decreases expression ISO myricetin results in decreased expression of LTN1 protein CTD PMID:29698783 NCBI chr11:40,090,169...40,147,159
Ensembl chr11:40,090,169...40,147,303
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions ISO myricetin binds to and results in decreased activity of MAP2K1 protein; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MAP2K1 protein] CTD PMID:17693661 NCBI chr 8:73,578,747...73,650,184
Ensembl chr 8:73,578,752...73,650,184
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 decreases phosphorylation ISO Myricetin decreases phosphorylation of Map3k7 protein in the heart RGD PMID:31885808 RGD:155791644 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:51,154,352...51,212,012
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases activity
ISO myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK1 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]
myricetin results in decreased activity of MAPK1 protein
CTD PMID:17693661 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK3 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein] CTD PMID:17693661 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO myricetin inhibits the reaction [EGF protein results in increased phosphorylation of MAPK9 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK9 protein] CTD PMID:17693661 NCBI chr10:34,670,750...34,711,972
Ensembl chr10:34,670,756...34,712,228
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase multiple interactions ISO myricetin inhibits the reaction [HGF protein results in increased phosphorylation of MET protein] CTD PMID:19244381 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:46,756,506...46,870,821
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein] CTD PMID:19804834 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:174,084,123...174,111,442
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
multiple interactions
ISO myricetin results in decreased expression of MYC protein
[myricetin results in increased activity of SIRT1 protein] which results in decreased expression of MYC protein
CTD PMID:22245592 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:95,483,105...95,488,028
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression ISO myricetin results in increased expression of NFE2L2 protein CTD PMID:16799064 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:81,001,529...81,029,090
JBrowse link
G Nme1 NME/NM23 nucleoside diphosphate kinase 1 increases expression ISO myricetin results in increased expression of NME1 protein CTD PMID:29698783 NCBI chr10:79,403,939...79,426,620
Ensembl chr10:79,403,940...79,413,310
JBrowse link
G Ocln occludin multiple interactions EXP myricetin inhibits the reaction [Indomethacin results in decreased expression of OCLN mRNA]; myricetin inhibits the reaction [Indomethacin results in decreased expression of OCLN protein] CTD PMID:33276066 NCBI chr 2:33,391,303...33,442,207
Ensembl chr 2:33,391,303...33,430,411
JBrowse link
G Parg poly (ADP-ribose) glycohydrolase decreases activity ISO myricetin results in decreased activity of PARG protein CTD PMID:19840838 NCBI chr16:7,442,696...7,550,585
Ensembl chr16:7,442,726...7,550,584
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage
decreases activity
ISO myricetin results in increased cleavage of PARP1 protein
myricetin results in decreased activity of PARP1 protein
CTD PMID:15748703 PMID:17884996 PMID:29698783 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:94,839,433...94,871,567
JBrowse link
G Pik3c2b phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta decreases expression ISO myricetin results in decreased expression of PIK3C2B protein CTD PMID:29698783 NCBI chr13:47,046,866...47,107,733
Ensembl chr13:47,047,127...47,107,725
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of PPARA protein] CTD PMID:25240712 NCBI chr 7:118,712,261...118,780,723
Ensembl chr 7:118,712,412...118,780,714
JBrowse link
G Psca prostate stem cell antigen decreases expression ISO myricetin results in decreased expression of PSCA mRNA CTD PMID:18331776 NCBI chr 7:108,483,974...108,492,098
Ensembl chr 7:108,484,184...108,492,097
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 mRNA]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
CTD PMID:17944529 PMID:19804834 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] affects the localization of and results in increased activity of RELA protein] CTD PMID:18958421 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:212,333,035...212,364,817
JBrowse link
G Rps12 ribosomal protein S12 decreases expression ISO myricetin results in decreased expression of RPS12 protein CTD PMID:29698783 NCBI chr 1:23,499,943...23,502,234
Ensembl chr 1:23,500,073...23,502,235
JBrowse link
G Rps6ka1 ribosomal protein S6 kinase A1 multiple interactions ISO myricetin inhibits the reaction [EGF protein results in increased phosphorylation of RPS6KA1 protein]; myricetin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of RPS6KA1 protein] CTD PMID:17693661 NCBI chr 5:151,362,819...151,402,064
Ensembl chr 5:151,362,819...151,476,044
JBrowse link
G Rps6kb2 ribosomal protein S6 kinase B2 increases expression ISO myricetin results in increased expression of RPS6KB2 protein CTD PMID:29698783 NCBI chr 1:210,880,824...210,887,556
Ensembl chr 1:210,880,825...210,887,562
JBrowse link
G Sirt1 sirtuin 1 increases activity
increases expression
multiple interactions
ISO myricetin results in increased activity of SIRT1 protein
myricetin results in increased expression of SIRT1 protein
[myricetin results in increased activity of SIRT1 protein] which results in decreased expression of CTNNB1 protein; [myricetin results in increased activity of SIRT1 protein] which results in decreased expression of EGLN1 protein; [myricetin results in increased activity of SIRT1 protein] which results in decreased expression of MYC protein; [myricetin results in increased activity of SIRT1 protein] which results in increased expression of HIF1A protein
CTD PMID:22245592 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,305,476...25,328,000
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions
decreases activity
ISO Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 mRNA]]; Deferoxamine inhibits the reaction [myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 protein]]; myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 mRNA]; myricetin inhibits the reaction [Formaldehyde results in increased expression of SLC2A1 protein]; myricetin inhibits the reaction [SLC2A1 protein affects the transport of Glucose]
myricetin results in decreased activity of SLC2A1 protein
CTD PMID:14642735 PMID:36116563 NCBI chr 5:138,002,522...138,030,742
Ensembl chr 5:138,002,522...138,030,742
JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in decreased expression of SLC2A2 protein] CTD PMID:24923654 NCBI chr 2:113,537,884...113,568,422
Ensembl chr 2:113,537,972...113,568,467
JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions EXP myricetin inhibits the reaction [Indomethacin results in increased phosphorylation of SRC protein] CTD PMID:33276066 NCBI chr 3:166,511,616...166,559,463
Ensembl chr 3:166,511,985...166,559,462
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF1 protein] CTD PMID:25240712 NCBI chr10:45,507,152...45,529,164
Ensembl chr10:45,507,152...45,529,164
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF2 protein] CTD PMID:25240712 NCBI chr 7:115,542,774...115,600,945
Ensembl chr 7:115,543,290...115,600,943
JBrowse link
G Star steroidogenic acute regulatory protein multiple interactions ISO myricetin promotes the reaction [Cyclic AMP results in increased expression of STAR mRNA] CTD PMID:28668616 NCBI chr16:72,969,824...72,974,447
Ensembl chr16:72,961,518...72,974,447
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO myricetin inhibits the reaction [EGF protein results in increased expression of STAT3 mRNA]; myricetin inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein] CTD PMID:18995957 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:86,311,535...86,363,359
JBrowse link
G Stk38l serine/threonine kinase 38 like decreases expression ISO myricetin results in decreased expression of STK38L protein CTD PMID:29698783 NCBI chr 4:181,346,969...181,423,844
Ensembl chr 4:181,364,919...181,423,840
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of TGFB1 protein] CTD PMID:25240712 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions EXP myricetin inhibits the reaction [Indomethacin results in decreased expression of TJP1 mRNA]; myricetin inhibits the reaction [Indomethacin results in decreased expression of TJP1 protein] CTD PMID:33276066 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:128,260,330...128,505,158
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
myricetin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased secretion of TNF protein]
myricetin inhibits the reaction [Ethanol results in increased expression of TNF protein]
CTD PMID:18958421 PMID:35156864 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Top2a DNA topoisomerase II alpha decreases activity ISO myricetin results in decreased activity of TOP2A protein CTD PMID:16536579 NCBI chr10:84,441,954...84,473,093
Ensembl chr10:84,441,954...84,473,366
JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions
ISO myricetin analog results in increased expression of TP53 mRNA; myricetin analog results in increased expression of TP53 protein; myricetin results in increased expression of TP53 protein
myricetin affects the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine affects the expression of TP53 mRNA]
CTD PMID:32220605 PMID:32342131 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 increases expression ISO myricetin results in increased expression of TP53I3 mRNA; myricetin results in increased expression of TP53I3 protein CTD PMID:19397994 NCBI chr 6:33,537,779...33,545,204 JBrowse link
G Tp63 tumor protein p63 increases expression ISO myricetin results in increased expression of TP63 protein CTD PMID:19397994 NCBI chr11:88,343,647...88,554,543
Ensembl chr11:88,343,651...88,554,177
JBrowse link
G Tp73 tumor protein p73 increases expression ISO myricetin results in increased expression of TP73 protein CTD PMID:19397994 NCBI chr 5:169,903,801...169,988,075
Ensembl chr 5:169,903,801...169,963,552
JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases activity
multiple interactions
EXP myricetin results in decreased activity of TXNRD1 protein modified form
[Xanthine co-treated with XDH protein] promotes the reaction [myricetin results in decreased activity of TXNRD1 protein modified form]; Nitrogen inhibits the reaction [myricetin results in decreased activity of TXNRD1 protein modified form]
CTD PMID:16618767 NCBI chr 7:22,717,620...22,802,553
Ensembl chr 7:22,719,317...22,739,817
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 decreases activity ISO myricetin results in decreased activity of UGT1A1 protein CTD PMID:35063619 NCBI chr 9:96,249,143...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 decreases activity ISO myricetin results in decreased activity of UGT1A3 protein CTD PMID:35063619 NCBI chr 9:96,239,019...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 decreases activity ISO myricetin results in decreased activity of UGT1A6 protein CTD PMID:35063619 NCBI chr 9:96,195,018...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 decreases activity ISO myricetin results in decreased activity of UGT1A9 protein CTD PMID:35063619 NCBI chr 9:96,144,786...96,256,264
Ensembl chr 9:96,144,786...96,256,264
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 decreases activity ISO myricetin results in decreased activity of UGT2B7 protein CTD PMID:35063619 NCBI chr14:21,251,535...21,274,451
Ensembl chr14:21,251,535...21,274,451
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP
ISO
myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of VEGFA protein]
myricetin inhibits the reaction [cobaltous chloride results in increased expression of VEGFA mRNA]; myricetin promotes the reaction [Oxygen deficiency results in increased secretion of VEGFA protein]
CTD PMID:20153296 PMID:25240712 PMID:26800359 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:22,439,392...22,468,194
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions EXP [Xanthine co-treated with XDH protein] promotes the reaction [myricetin results in decreased activity of TXNRD1 protein modified form]; myricetin inhibits the reaction [Ethanol results in increased activity of XDH protein] CTD PMID:16618767 PMID:35156864 NCBI chr 6:27,282,319...27,344,022
Ensembl chr 6:27,282,057...27,344,350
JBrowse link
(+)-dihydromyricetin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK1 protein] CTD PMID:21871475 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK3 protein] CTD PMID:21871475 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions EXP ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK1 protein]; ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of MAPK3 protein]; ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PDGFRB protein]; ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PLCG1 protein] CTD PMID:21871475 NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:113,420,710...113,438,343
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions EXP ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PDGFRB protein] CTD PMID:21871475 NCBI chr18:56,770,348...56,809,228
Ensembl chr18:56,770,348...56,809,233
JBrowse link
G Plcg1 phospholipase C, gamma 1 multiple interactions EXP ampelopsin analog inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased phosphorylation of PLCG1 protein] CTD PMID:21871475 NCBI chr 3:169,805,299...169,836,040
Ensembl chr 3:169,804,846...169,836,050
JBrowse link
G Sphk1 sphingosine kinase 1 decreases expression
decreases activity
ISO ampelopsin results in decreased expression of SPHK1 protein
ampelopsin results in decreased activity of SPHK1 protein
CTD PMID:22251058 NCBI chr10:102,257,413...102,263,086
Ensembl chr10:102,258,975...102,263,082
JBrowse link
myricitrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:25656916 NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:241,159,724...241,172,503
JBrowse link
G Alpl alkaline phosphatase, biomineralization associated multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of ALPL mRNA] CTD PMID:25130202 NCBI chr 5:155,234,770...155,289,785
Ensembl chr 5:155,234,775...155,254,167
JBrowse link
G Apoe apolipoprotein E multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in decreased activity of CAT protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased activity of CASP3 protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CCL2 protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CRP protein]; myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of ICAM1 protein] CTD PMID:23639522 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:88,481,385...88,485,855
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein] CTD PMID:23639522 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:105,076,473...105,086,429
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:23639522 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:23,204,464...23,366,900
JBrowse link
G Bglap bone gamma-carboxyglutamate protein multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of BGLAP mRNA] CTD PMID:25130202 NCBI chr 2:176,136,341...176,137,318
Ensembl chr 2:176,136,341...176,137,318
JBrowse link
G Casp3 caspase 3 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]
myricitrin inhibits the reaction [APOE gene mutant form results in increased activity of CASP3 protein]
CTD PMID:23639522 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:52,395,540...52,413,732
JBrowse link
G Cat catalase multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein]
myricitrin inhibits the reaction [APOE gene mutant form results in decreased activity of CAT protein]
CTD PMID:23639522 NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:110,297,342...110,329,526
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CCL2 protein] CTD PMID:23639522 NCBI chr10:67,503,077...67,504,875
Ensembl chr10:67,503,077...67,504,875
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased expression of COL1A1 mRNA] CTD PMID:25130202 NCBI chr10:80,380,458...80,397,461
Ensembl chr10:80,380,453...80,397,460
JBrowse link
G Crp C-reactive protein multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of CRP protein] CTD PMID:23639522 NCBI chr13:87,694,062...87,695,978
Ensembl chr13:87,657,317...87,707,514
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP2E1 protein] CTD PMID:25656916 NCBI chr 1:205,269,967...205,280,365
Ensembl chr 1:205,267,505...205,293,495
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein] CTD PMID:25656916 NCBI chr 7:110,295,599...110,300,134
Ensembl chr 7:110,296,206...110,300,160
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of GPX1 protein] CTD PMID:23639522 NCBI chr 8:117,905,462...117,906,588
Ensembl chr 8:117,905,280...117,906,581
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO myricitrin inhibits the reaction [APOE gene mutant form results in increased expression of ICAM1 protein] CTD PMID:23639522 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:27,829,161...27,841,617
JBrowse link
G Il6 interleukin 6 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of IL6 protein] CTD PMID:25130202 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,889,999...5,894,610
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein] CTD PMID:23639522 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:97,462,025...97,527,825
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein] CTD PMID:23639522 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:190,797,185...190,803,411
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein] CTD PMID:23639522 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,645,198...8,728,427
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in decreased activity of NOS3 protein] CTD PMID:23639522 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:11,686,268...11,706,664
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO myricitrin promotes the reaction [Carbon Tetrachloride results in increased expression of PCNA protein] CTD PMID:25656916 NCBI chr 3:139,951,948...139,955,820
Ensembl chr 3:139,951,941...139,955,901
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of PPARG mRNA] CTD PMID:25130202 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:150,095,787...150,221,104
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein] CTD PMID:25656916 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:64,713,619...64,722,320
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein] CTD PMID:25656916 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:90,324,046...90,340,899
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO myricitrin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein] CTD PMID:25656916 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,626,532...3,629,303
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of TNFSF11 protein] CTD PMID:25130202 NCBI chr15:60,083,008...60,114,479
Ensembl chr15:60,083,008...60,114,479
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO myricitrin inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein] CTD PMID:23639522 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,798,851...54,810,299
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20873
    role 20805
      chemical role 20383
        antioxidant 16456
          myricetin 125
            3',5,7-trihydroxy-3,4',5'-trimethoxyflavone 0
            3',5-dihydroxy-3,4',5',7-tetramethoxyflavone 0
            3,3',4',5'-tetramethylmyricetin 0
            3,3',5'-trimethylmyricetin 0
            5,7,3',5'-tetrahydroxy-3,4'-dimethyoxyflavone 0
            7,3',5'-trimethylmyricetin 0
            7-O-methylmyricetin 0
            combretol 0
            dihydromyricetin + 6
            laricitrin 0
            myricetin 3-O-[(6-O-trans-4-coumaroyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside] 0
            myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] + 0
            myricetin 3-O-beta-D-galactopyranoside 0
            myricetin 3-O-beta-L-galactopyranoside 0
            myricetin O-glucoside + 0
            myricetin O-glucuronide + 0
            myricetin-3-O-arabinofuranoside 0
            myricetin-3-O-beta-D-xylopyranoside 0
            myricitrin + 27
            syringetin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20873
    subatomic particle 20871
      composite particle 20871
        hadron 20871
          baryon 20871
            nucleon 20871
              atomic nucleus 20871
                atom 20871
                  main group element atom 20794
                    p-block element atom 20794
                      carbon group element atom 20727
                        carbon atom 20722
                          organic molecular entity 20722
                            organic molecule 20666
                              organic cyclic compound 20416
                                organic heterocyclic compound 19388
                                  oxacycle 18294
                                    benzopyran 12178
                                      1-benzopyran 11910
                                        flavonoid 7547
                                          anthoxanthin 4621
                                            flavones 4619
                                              hydroxyflavone 4598
                                                flavonols 4464
                                                  7-hydroxyflavonol 4430
                                                    myricetin 125
                                                      3',5,7-trihydroxy-3,4',5'-trimethoxyflavone 0
                                                      3',5-dihydroxy-3,4',5',7-tetramethoxyflavone 0
                                                      3,3',4',5'-tetramethylmyricetin 0
                                                      3,3',5'-trimethylmyricetin 0
                                                      5,7,3',5'-tetrahydroxy-3,4'-dimethyoxyflavone 0
                                                      7,3',5'-trimethylmyricetin 0
                                                      7-O-methylmyricetin 0
                                                      combretol 0
                                                      dihydromyricetin + 6
                                                      laricitrin 0
                                                      myricetin 3-O-[(6-O-trans-4-coumaroyl-beta-D-glucosyl)-(1->2)-alpha-L-rhamnoside] 0
                                                      myricetin 3-O-[beta-D-glucosyl-(1->2)-alpha-L-rhamnoside] + 0
                                                      myricetin 3-O-beta-D-galactopyranoside 0
                                                      myricetin 3-O-beta-L-galactopyranoside 0
                                                      myricetin O-glucoside + 0
                                                      myricetin O-glucuronide + 0
                                                      myricetin-3-O-arabinofuranoside 0
                                                      myricetin-3-O-beta-D-xylopyranoside 0
                                                      myricitrin + 27
                                                      syringetin 0
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