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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:acetylsalicylic acid
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Accession:CHEBI:15365 term browser browse the term
Definition:A member of the class of benzoic acids that is salicylic acid in which the hydrogen that is attached to the phenolic hydroxy group has been replaced by an acetoxy group. A non-steroidal anti-inflammatory drug with cyclooxygenase inhibitor activity.
Synonyms:related_synonym: 2-(ACETYLOXY)BENZOIC ACID;   2-Acetoxybenzenecarboxylic acid;   2-acetoxybenzoic acid;   ASA;   Acetylsalicylate;   Acetylsalicylsaeure;   Aspirin;   Azetylsalizylsaeure;   Easprin;   Formula=C9H8O4;   InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12);   InChIKey=BSYNRYMUTXBXSQ-UHFFFAOYSA-N;   O-acetylsalicylic acid;   SMILES=CC(=O)Oc1ccccc1C(O)=O;   acide 2-(acetyloxy)benzoique;   acide acetylsalicylique;   acido acetilsalicilico;   acidum acetylsalicylicum;   o-acetoxybenzoic acid;   o-carboxyphenyl acetate;   salicylic acid acetate
 alt_id: CHEBI:22188;   CHEBI:22203;   CHEBI:2890;   CHEBI:40705;   CHEBI:71414
 xref: Beilstein:779271;   CAS:50-78-2;   DrugBank:DB00945;   Drug_Central:74;   Gmelin:218864;   HMDB:HMDB0001879;   KEGG:C01405;   KEGG:D00109;   LINCS:LSM-5288
 xref_mesh: MESH:D001241
 xref: MetaCyc:CPD-524;   PDBeChem:AIN;   PMID:11203441;   PMID:11402787;   PMID:11597554;   PMID:11733186;   PMID:12852484;   PMID:14753751;   PMID:15542410;   PMID:15590729;   PMID:1650428;   PMID:18226435;   PMID:18335236;   PMID:19010312;   PMID:19386367;   PMID:19706045;   PMID:21699808;   PMID:22866967;   PMID:445303;   Reaxys:779271;   Wikipedia:Aspirin
 cyclic_relationship: is_conjugate_acid_of CHEBI:13719


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acetylsalicylic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 decreases expression
multiple interactions
affects expression
increases expression
ISO Aspirin results in decreased expression of ABCA1 mRNA
Aspirin affects the expression of and affects the activity of ABCA1 protein; PPARA affects the reaction [Aspirin affects the expression of ABCA1 mRNA]; PPARA affects the reaction [Aspirin affects the expression of ABCA1 protein]
Aspirin results in increased expression of ABCA1 mRNA; Aspirin results in increased expression of ABCA1 protein
CTD PMID:15037193, PMID:20137092, PMID:21088444 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
multiple interactions
increases activity
ISO
EXP
Aspirin results in increased expression of ABCB1 mRNA; Aspirin results in increased expression of ABCB1 protein
[Aspirin results in increased expression of ABCB1 protein] which results in decreased uptake of clopidogrel
Aspirin results in increased activity of ABCB1 protein
CTD PMID:19840843, PMID:21900887 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases activity EXP Aspirin results in increased activity of ABCB1B protein CTD PMID:19840843 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases expression ISO Aspirin results in increased expression of ABCC1 mRNA; Aspirin results in increased expression of ABCC1 protein CTD PMID:21900887 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression ISO Aspirin results in increased expression of ABCC4 mRNA; Aspirin results in increased expression of ABCC4 protein CTD PMID:21900887 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 increases expression ISO Aspirin results in increased expression of ABCC5 mRNA; Aspirin results in increased expression of ABCC5 protein CTD PMID:21900887 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases expression
multiple interactions
ISO Aspirin results in increased expression of ACACA protein modified form
CES1 protein promotes the reaction [Aspirin results in increased expression of ACACA protein modified form]
CTD PMID:25743752 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acadm acyl-CoA dehydrogenase medium chain increases expression ISO Aspirin results in increased expression of ACADM mRNA; Aspirin results in increased expression of ACADM protein CTD PMID:25743752 NCBI chr 2:260,124,418...260,148,589
Ensembl chr 2:260,124,418...260,148,589
JBrowse link
G Acap3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 increases expression ISO Aspirin results in increased expression of ACAP3 mRNA CTD PMID:11906190 NCBI chr 5:173,340,060...173,354,756
Ensembl chr 5:173,340,060...173,354,755
JBrowse link
G Ace angiotensin I converting enzyme affects response to substance ISO ACE polymorphism affects the susceptibility to Aspirin CTD PMID:18727619 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Acin1 apoptotic chromatin condensation inducer 1 decreases expression
increases expression
ISO Aspirin results in decreased expression of ACIN1 mRNA
Aspirin results in increased expression of ACIN1 mRNA
CTD PMID:11906190, PMID:15928584 NCBI chr15:33,288,369...33,333,256
Ensembl chr15:33,288,374...33,333,417
JBrowse link
G Actb actin, beta multiple interactions ISO Aspirin inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY analog results in increased secretion of ACTB protein] CTD PMID:17303692 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Actr3 actin related protein 3 decreases expression ISO Aspirin results in decreased expression of ACTR3 mRNA CTD PMID:11906190 NCBI chr13:41,695,520...41,738,622
Ensembl chr13:41,695,183...41,738,658
JBrowse link
G Adam33 ADAM metallopeptidase domain 33 affects response to substance ISO ADAM33 SNP affects the susceptibility to Aspirin CTD PMID:17061022 NCBI chr 3:123,595,018...123,607,549
Ensembl chr 3:123,595,560...123,607,352
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 decreases expression ISO Aspirin results in decreased expression of ADAMTS1 mRNA CTD PMID:15456535 NCBI chr11:25,342,119...25,350,938
Ensembl chr11:25,342,126...25,350,974
JBrowse link
G Adk adenosine kinase affects binding EXP Aspirin binds to ADK protein CTD PMID:15236443 NCBI chr15:3,033,535...3,435,888
Ensembl chr15:3,033,495...3,435,888
JBrowse link
G Adora1 adenosine A1 receptor affects response to substance ISO ADORA1 polymorphism affects the susceptibility to Aspirin CTD PMID:19019667 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adora2a adenosine A2a receptor affects response to substance ISO ADORA2A polymorphism affects the susceptibility to Aspirin CTD PMID:19019667 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Adora3 adenosine A3 receptor affects response to substance ISO ADORA3 protein affects the susceptibility to Aspirin CTD PMID:20716228 NCBI chr 2:208,336,909...208,379,217
Ensembl chr 2:208,373,154...208,376,803
JBrowse link
G Adrb2 adrenoceptor beta 2 affects response to substance ISO ADRB2 polymorphism affects the susceptibility to Aspirin; ADRB2 SNP affects the susceptibility to Aspirin CTD PMID:18159608, PMID:18379861 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Agt angiotensinogen affects activity ISO Aspirin affects the activity of AGT protein CTD PMID:3189434 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions ISO Aspirin inhibits the reaction [Hydrogen Peroxide results in increased expression of AGTR1A mRNA] CTD PMID:22306536 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Ahr aryl hydrocarbon receptor increases expression
multiple interactions
ISO
EXP
Aspirin results in increased expression of AHR mRNA
AHR mutant form inhibits the reaction [Aspirin results in increased activity of PON1 protein]; AHR mutant form inhibits the reaction [Aspirin results in increased expression of APOA1 mRNA]; AHR mutant form inhibits the reaction [Aspirin results in increased expression of PON1 mRNA]
CTD PMID:18519978 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aif1l allograft inflammatory factor 1-like increases expression ISO Aspirin results in increased expression of AIF1L mRNA CTD PMID:11906190 NCBI chr 3:9,237,944...9,262,628
Ensembl chr 3:9,237,944...9,262,628
JBrowse link
G Aimp2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 decreases expression EXP Aspirin results in decreased expression of AIMP2 mRNA CTD PMID:12800193 NCBI chr12:12,738,784...12,748,345
Ensembl chr12:12,738,812...12,748,345
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases activity ISO Aspirin results in decreased activity of AKR1C2 protein CTD PMID:19010312 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases activity ISO Aspirin results in decreased activity of AKR1C3 protein CTD PMID:19010312 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions
increases expression
increases activity
ISO [troglitazone co-treated with Aspirin] results in decreased expression of AKT1 protein; [troglitazone co-treated with Aspirin] results in decreased expression of AKT1 protein modified form; Aspirin results in decreased phosphorylation of and results in decreased activity of AKT1 protein
Aspirin results in increased expression of AKT1 mRNA
Aspirin results in increased activity of AKT1 protein
CTD PMID:19908241, PMID:20116423, PMID:20457246, PMID:21617849 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 increases expression ISO Aspirin results in increased expression of AKT2 mRNA CTD PMID:11906190 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression EXP Aspirin results in increased expression of ALAS1 mRNA CTD PMID:12800193 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177
JBrowse link
G Alb albumin multiple interactions
decreases secretion
ISO ALB protein binds to and affects the transport of Aspirin; Aspirin inhibits the reaction [Adenosine Diphosphate results in decreased secretion of ALB protein]; Aspirin inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY analog results in increased secretion of ALB protein]; Aspirin inhibits the reaction [Warfarin binds to ALB protein]; Aspirin inhibits the reaction [zomepirac glucuronide binds to ALB protein]; Aspirin promotes the reaction [menadione epoxide analog binds to ALB protein]
Aspirin results in decreased secretion of ALB protein
CTD PMID:1981713, PMID:8831264, PMID:17303692, PMID:25499135 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects binding EXP Aspirin binds to ALDH1A1 protein CTD PMID:15236443 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A decreases expression ISO Aspirin results in decreased expression of ALDOA mRNA CTD PMID:15928584 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Angptl3 angiopoietin-like 3 decreases expression ISO Aspirin results in decreased expression of ANGPTL3 mRNA CTD PMID:27089845 NCBI chr 5:117,698,590...117,706,729
Ensembl chr 5:117,698,764...117,705,808
JBrowse link
G Ano9 anoctamin 9 increases expression ISO Aspirin results in increased expression of ANO9 mRNA CTD PMID:11906190 NCBI chr 1:213,908,389...213,929,291
Ensembl chr 1:213,908,982...213,921,208
JBrowse link
G Anpep alanyl aminopeptidase, membrane increases activity
increases expression
ISO Aspirin results in increased activity of ANPEP protein
Aspirin results in increased expression of ANPEP mRNA; Aspirin results in increased expression of ANPEP protein
CTD PMID:16216591 NCBI chr 1:141,561,364...141,604,249
Ensembl chr 1:141,561,334...141,604,273
JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 decreases expression ISO Aspirin results in decreased expression of AP2B1 mRNA CTD PMID:11906190 NCBI chr10:70,516,462...70,621,973
Ensembl chr10:70,520,206...70,621,977
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases response to substance
increases expression
ISO APAF1 results in increased susceptibility to Aspirin
Aspirin results in increased expression of APAF1 mRNA
CTD PMID:11228543, PMID:20457246 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions
increases expression
increases activity
ISO
EXP
AHR mutant form inhibits the reaction [Aspirin results in increased expression of APOA1 mRNA]; Aspirin promotes the reaction [APOA1 affects the transport of Cholesterol]; PPARA affects the reaction [Aspirin promotes the reaction [APOA1 affects the transport of Cholesterol]]
Aspirin results in increased activity of APOA1 mRNA
CTD PMID:9399670, PMID:18519978, PMID:21088444 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apoc1 apolipoprotein C1 multiple interactions ISO Aspirin inhibits the reaction [APOC1 results in increased abundance of Triglycerides] CTD PMID:21862721 NCBI chr 1:80,606,638...80,609,921
Ensembl chr 1:80,606,638...80,609,921
JBrowse link
G Apoe apolipoprotein E affects response to substance
multiple interactions
ISO APOE polymorphism affects the susceptibility to Aspirin
Aspirin inhibits the reaction [APOE gene mutant form results in decreased susceptibility to Arachidonic Acid]
Aspirin inhibits the reaction [APOE gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]]
CTD PMID:15084783, PMID:20530721 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Aprt adenine phosphoribosyl transferase decreases expression ISO Aspirin results in decreased expression of APRT mRNA CTD PMID:15928584 NCBI chr19:55,387,288...55,389,256
Ensembl chr19:55,387,288...55,389,256
JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 increases expression ISO Aspirin results in increased expression of ARL6IP5 mRNA CTD PMID:15928584 NCBI chr 4:129,574,363...129,598,240
Ensembl chr 4:129,574,264...129,598,915
JBrowse link
G Arpp19 cAMP-regulated phosphoprotein 19 increases expression ISO Aspirin results in increased expression of ARPP19 mRNA CTD PMID:15928584 NCBI chr 8:81,949,577...81,972,054
Ensembl chr 8:81,949,877...81,968,589
JBrowse link
G Asic1 acid sensing ion channel subunit 1 decreases expression EXP Aspirin results in decreased expression of ASIC1 mRNA CTD PMID:11588175 NCBI chr 7:141,324,714...141,354,937
Ensembl chr 7:141,326,321...141,354,937
JBrowse link
G Asic2 acid sensing ion channel subunit 2 decreases expression EXP Aspirin results in decreased expression of ASIC2 mRNA CTD PMID:11588175 NCBI chr10:68,247,800...69,347,223
Ensembl chr10:68,248,655...68,517,564
JBrowse link
G Asic3 acid sensing ion channel subunit 3 decreases expression
decreases activity
EXP Aspirin results in decreased expression of ASIC3 mRNA
Aspirin results in decreased activity of ASIC3 protein
CTD PMID:11588175 NCBI chr 4:7,287,868...7,293,295
Ensembl chr 4:7,288,855...7,292,901
JBrowse link
G Asl argininosuccinate lyase decreases expression ISO Aspirin results in decreased expression of ASL mRNA CTD PMID:15928584 NCBI chr12:30,160,922...30,178,348
Ensembl chr12:30,165,694...30,178,341
JBrowse link
G Astn2 astrotactin 2 increases expression ISO Aspirin results in increased expression of ASTN2 mRNA CTD PMID:11906190 NCBI chr 5:81,179,614...82,168,528
Ensembl chr 5:81,179,605...82,168,427
JBrowse link
G Atf4 activating transcription factor 4 decreases expression ISO Aspirin results in decreased expression of ATF4 mRNA CTD PMID:15928584 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atm ATM serine/threonine kinase increases expression ISO Aspirin results in increased expression of ATM mRNA CTD PMID:20457246 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 increases expression ISO Aspirin results in increased expression of ATP2A1 mRNA CTD PMID:11906190 NCBI chr 1:197,855,912...197,875,038 JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon increases expression ISO Aspirin results in increased expression of ATP5F1E mRNA CTD PMID:15928584 NCBI chr 3:172,563,105...172,566,007
Ensembl chr 3:172,563,105...172,566,010
JBrowse link
G Atp6v0b ATPase H+ transporting V0 subunit B decreases expression ISO Aspirin results in decreased expression of ATP6V0B mRNA CTD PMID:15928584 NCBI chr 5:136,718,352...136,719,868
Ensembl chr 5:136,718,352...136,721,379
JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 decreases expression ISO Aspirin results in decreased expression of ATP6V0D1 mRNA CTD PMID:15928584 NCBI chr19:37,481,782...37,525,762
Ensembl chr19:37,481,782...37,525,762
JBrowse link
G Atr ATR serine/threonine kinase decreases expression ISO Aspirin results in decreased expression of ATR mRNA CTD PMID:20514442 NCBI chr 8:103,673,578...103,770,886
Ensembl chr 8:103,673,411...103,770,947
JBrowse link
G Atraid all-trans retinoic acid-induced differentiation factor decreases expression ISO Aspirin results in decreased expression of ATRAID mRNA CTD PMID:15928584 NCBI chr 6:26,680,628...26,685,185
Ensembl chr 6:26,680,598...26,685,235
JBrowse link
G Aurka aurora kinase A increases expression ISO Aspirin results in increased expression of AURKA mRNA CTD PMID:11906190 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
JBrowse link
G B2m beta-2 microglobulin increases expression ISO Aspirin results in increased expression of B2M mRNA CTD PMID:15456535 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G B4galt1 beta-1,4-galactosyltransferase 1 increases expression ISO Aspirin results in increased expression of B4GALT1 mRNA CTD PMID:15456535 NCBI chr 5:57,121,768...57,168,610
Ensembl chr 5:57,121,769...57,168,610
JBrowse link
G Bad BCL2-associated agonist of cell death decreases expression ISO Aspirin results in decreased expression of BAD mRNA CTD PMID:20457246 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO Aspirin results in increased expression of BAK1 protein CTD PMID:11532860 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bap1 Brca1 associated protein 1 decreases expression ISO Aspirin results in decreased expression of BAP1 mRNA CTD PMID:15928584 NCBI chr16:7,336,685...7,345,511
Ensembl chr16:7,336,685...7,345,511
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
increases localization
decreases expression
ISO
EXP
Aspirin promotes the reaction [Fluorouracil results in increased expression of BAX protein]; CASP8 affects the reaction [Aspirin results in increased localization of BAX protein]; Fluorouracil promotes the reaction [Aspirin results in increased expression of BAX protein]
Bee Venoms inhibits the reaction [Aspirin results in increased expression of BAX protein]; Ranitidine inhibits the reaction [Aspirin results in increased expression of BAX protein]
Aspirin results in decreased expression of BAX mRNA; Aspirin results in decreased expression of BAX protein
CTD PMID:11228543, PMID:11532860, PMID:15976387, PMID:15986848, PMID:16880202, PMID:18636671, PMID:19212664, PMID:20457246, PMID:30885738 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B decreases expression ISO Aspirin results in decreased expression of BAZ1B mRNA CTD PMID:15928584 NCBI chr12:24,478,882...24,536,851
Ensembl chr12:24,478,898...24,537,313
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression
increases response to substance
ISO Aspirin results in increased expression of BBC3 mRNA
BBC3 results in increased susceptibility to Aspirin
CTD PMID:19936928 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bbof1 basal body orientation factor 1 increases expression ISO Aspirin results in increased expression of BBOF1 mRNA CTD PMID:11906190 NCBI chr 6:108,123,855...108,149,613
Ensembl chr 6:108,123,816...108,149,607
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
increases expression
ISO
EXP
Aspirin inhibits the reaction [Methotrexate results in decreased expression of BCL2 protein]; BCL2 protein inhibits the reaction [[TNFSF10 protein co-treated with Aspirin] results in increased cleavage of and results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [[TNFSF10 protein co-treated with Aspirin] results in increased cleavage of and results in increased activity of CASP9 protein]; BCL2 protein inhibits the reaction [Aspirin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]
Aspirin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BCL2 protein]
Aspirin results in decreased expression of BCL2 mRNA; Aspirin results in decreased expression of BCL2 protein
Aspirin inhibits the reaction [Azoxymethane results in increased expression of BCL2 mRNA]
Aspirin results in increased expression of BCL2 mRNA; Aspirin results in increased expression of BCL2 protein
CTD PMID:12490308, PMID:14636445, PMID:15976387, PMID:16199534, PMID:17342322, PMID:18564172, PMID:18636671, PMID:19424877, PMID:19595669, PMID:19966835, PMID:20043115, PMID:20457246, PMID:20886344, PMID:23799623, PMID:25449198 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
increases expression
ISO Aspirin results in decreased expression of BCL2L1 protein
Aspirin results in increased expression of BCL2L1 mRNA
CTD PMID:17342322, PMID:20457246, PMID:20886344 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l11 BCL2 like 11 increases expression ISO Aspirin results in increased expression of BCL2L11 mRNA CTD PMID:19936928 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions
increases cleavage
ISO [Aspirin co-treated with TNFSF10 protein] results in increased cleavage of BID protein; CASP8 affects the reaction [Aspirin results in increased cleavage of BID protein] CTD PMID:15976387, PMID:18483385 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bin1 bridging integrator 1 increases expression EXP Aspirin results in increased expression of BIN1 mRNA CTD PMID:12800193 NCBI chr18:25,163,575...25,222,139
Ensembl chr18:25,163,561...25,222,135
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
increases expression
decreases expression
ISO [Aspirin co-treated with TNFSF10 protein] results in decreased expression of BIRC5 protein; Aspirin inhibits the reaction [E2F1 protein binds to BIRC5 promoter]; epoxomicin inhibits the reaction [Aspirin results in decreased expression of BIRC5 protein]
Aspirin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of BIRC5 protein]
Aspirin results in increased expression of BIRC5 mRNA
Aspirin results in decreased expression of BIRC5 mRNA; Aspirin results in decreased expression of BIRC5 protein
CTD PMID:11906190, PMID:17342322, PMID:17848598, PMID:18483385, PMID:25449198 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Blmh bleomycin hydrolase decreases expression ISO Aspirin results in decreased expression of BLMH mRNA CTD PMID:14976132 NCBI chr10:63,197,367...63,240,447
Ensembl chr10:63,197,364...63,240,332
JBrowse link
G Bmf Bcl2 modifying factor increases expression ISO Aspirin results in increased expression of BMF mRNA CTD PMID:19936928 NCBI chr 3:110,303,515...110,324,125
Ensembl chr 3:110,306,067...110,324,084
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO Aspirin results in increased expression of BNIP3L mRNA CTD PMID:15928584 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression ISO Aspirin results in decreased expression of BRCA1 mRNA CTD PMID:20457246, PMID:20514442 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Brd4 bromodomain containing 4 increases expression ISO Aspirin results in increased expression of BRD4 mRNA CTD PMID:11906190 NCBI chr 7:14,222,101...14,303,055
Ensembl chr 7:14,222,101...14,303,055
JBrowse link
G Btg1 BTG anti-proliferation factor 1 increases expression ISO
EXP
Aspirin results in increased expression of BTG1 mRNA CTD PMID:12800193, PMID:15928584 NCBI chr 7:37,812,831...37,815,088
Ensembl chr 7:37,812,831...37,815,088
JBrowse link
G Bzw1 basic leucine zipper and W2 domains 1 increases expression ISO Aspirin results in increased expression of BZW1 mRNA CTD PMID:15928584 NCBI chr 9:65,279,675...65,293,471
Ensembl chr 9:65,279,675...65,291,651
JBrowse link
G Cacng1 calcium voltage-gated channel auxiliary subunit gamma 1 decreases expression ISO Aspirin results in decreased expression of CACNG1 mRNA CTD PMID:11906190 NCBI chr10:95,921,479...95,934,170
Ensembl chr10:95,921,174...95,934,345
JBrowse link
G Cacng6 calcium voltage-gated channel auxiliary subunit gamma 6 affects response to substance ISO CACNG6 polymorphism affects the susceptibility to Aspirin CTD PMID:20860846 NCBI chr 1:64,307,684...64,322,124
Ensembl chr 1:64,305,438...64,321,241
JBrowse link
G Calca calcitonin-related polypeptide alpha decreases expression EXP Aspirin results in decreased expression of CALCA mRNA CTD PMID:11588175 NCBI chr 1:184,184,018...184,188,922
Ensembl chr 1:184,184,020...184,188,911
JBrowse link
G Calm1 calmodulin 1 multiple interactions ISO Aspirin promotes the reaction [NOS3 protein binds to CALM1 protein]; HDAC3 protein inhibits the reaction [Aspirin promotes the reaction [NOS3 protein binds to CALM1 protein]] CTD PMID:20705923 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Calm3 calmodulin 3 increases expression ISO Aspirin results in increased expression of CALM3 mRNA CTD PMID:11906190 NCBI chr 1:78,844,520...78,851,628
Ensembl chr 1:78,843,080...78,851,719
JBrowse link
G Canx calnexin decreases expression ISO Aspirin results in decreased expression of CANX mRNA CTD PMID:15928584 NCBI chr10:35,800,942...35,833,939
Ensembl chr10:35,800,942...35,833,861
JBrowse link
G Capn1 calpain 1 increases expression ISO Aspirin results in increased expression of CAPN1 mRNA CTD PMID:19266085 NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322
JBrowse link
G Capn2 calpain 2 increases expression ISO Aspirin results in increased expression of CAPN2 mRNA CTD PMID:15928584 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
JBrowse link
G Capns1 calpain, small subunit 1 decreases expression ISO Aspirin results in decreased expression of CAPNS1 mRNA CTD PMID:15928584 NCBI chr 1:91,058,528...91,064,880 JBrowse link
G Capsl calcyphosine-like increases expression ISO Aspirin results in increased expression of CAPSL mRNA CTD PMID:11906190 NCBI chr 2:58,724,855...58,755,220
Ensembl chr 2:58,724,855...58,747,843
JBrowse link
G Capza1 capping actin protein of muscle Z-line subunit alpha 1 increases expression ISO Aspirin results in increased expression of CAPZA1 mRNA CTD PMID:15928584 NCBI chr 2:207,305,748...207,350,812
Ensembl chr 2:207,305,752...207,350,812
JBrowse link
G Capza2 capping actin protein of muscle Z-line subunit alpha 2 increases expression ISO Aspirin results in increased expression of CAPZA2 mRNA CTD PMID:15928584 NCBI chr 4:44,936,290...44,972,270
Ensembl chr 4:44,936,290...44,972,267
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases expression
decreases expression
ISO
EXP
Aspirin results in increased activity of CASP3 protein
Bee Venoms inhibits the reaction [Aspirin results in increased expression of CASP3 mRNA]; Bee Venoms inhibits the reaction [Aspirin results in increased expression of CASP3 protein]; Ranitidine inhibits the reaction [Aspirin results in increased expression of CASP3 mRNA]; Ranitidine inhibits the reaction [Aspirin results in increased expression of CASP3 protein]
Aspirin results in increased expression of CASP3 mRNA; Aspirin results in increased expression of CASP3 protein
[Aspirin co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP3 protein; [TNFSF10 protein co-treated with Aspirin] results in increased cleavage of and results in increased activity of CASP3 protein; [troglitazone co-treated with Aspirin] results in increased cleavage of and results in increased activity of CASP3 protein; Aspirin inhibits the reaction [Deoxycholic Acid results in increased activity of CASP3 protein]; Aspirin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]; Aspirin inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]; Aspirin inhibits the reaction [Methotrexate results in decreased expression of CASP3 protein]; Aspirin results in increased cleavage of and results in increased activity of CASP3 protein; BCL2 protein inhibits the reaction [[TNFSF10 protein co-treated with Aspirin] results in increased cleavage of and results in increased activity of CASP3 protein]; CDKN1A mutant form inhibits the reaction [Aspirin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]]
Aspirin results in decreased expression of CASP3 mRNA
CTD PMID:11034327, PMID:11228543, PMID:11532860, PMID:12490308, PMID:14753751, PMID:15481331, PMID:16199534, PMID:16880202, PMID:17644113, PMID:18483385, PMID:19908241, PMID:21353610, PMID:21617849, PMID:23799623, PMID:30885738 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp6 caspase 6 multiple interactions ISO Aspirin inhibits the reaction [Deoxycholic Acid results in increased activity of CASP6 protein]; Aspirin results in increased cleavage of and results in increased activity of CASP6 protein CTD PMID:15481331, PMID:17644113 NCBI chr 2:235,341,326...235,353,715
Ensembl chr 2:235,341,365...235,353,967
Ensembl chr 2:235,341,365...235,353,967
JBrowse link
G Casp7 caspase 7 multiple interactions ISO Aspirin results in increased cleavage of and results in increased activity of CASP7 protein CTD PMID:15481331 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression
increases activity
ISO [Aspirin co-treated with TNFSF10 protein] results in increased activity of CASP8 protein; [Aspirin co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein; [TNFSF10 protein co-treated with Aspirin] results in increased cleavage of CASP8 protein; Aspirin results in increased cleavage of and results in increased activity of CASP8 protein; CASP8 affects the reaction [Aspirin results in increased cleavage of BID protein]; CASP8 affects the reaction [Aspirin results in increased localization of BAX protein]
Aspirin results in increased expression of CASP8 mRNA
Aspirin results in increased activity of CASP8 protein
CTD PMID:11034327, PMID:15481331, PMID:15976387, PMID:16199534, PMID:18483385, PMID:20457246, PMID:21171083 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
ISO [TNFSF10 protein co-treated with Aspirin] results in increased cleavage of and results in increased activity of CASP9 protein; Aspirin inhibits the reaction [Deoxycholic Acid results in increased activity of CASP9 protein]; Aspirin inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP9 protein]; Aspirin results in increased cleavage of and results in increased activity of CASP9 protein; BCL2 protein inhibits the reaction [[TNFSF10 protein co-treated with Aspirin] results in increased cleavage of and results in increased activity of CASP9 protein]
Aspirin results in increased activity of CASP9 protein
CTD PMID:11034327, PMID:14753751, PMID:15481331, PMID:16199534, PMID:16880202, PMID:17644113 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase decreases activity
increases expression
EXP Aspirin results in decreased activity of CAT; Aspirin results in decreased activity of CAT protein
Aspirin results in increased expression of CAT protein
CTD PMID:6845354, PMID:9212780, PMID:10528994, PMID:17147060, PMID:17274466 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 decreases expression EXP Aspirin results in decreased expression of CAV1 mRNA CTD PMID:12800193 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 increases expression ISO Aspirin results in increased expression of CCL19 mRNA CTD PMID:11906190 NCBI chr 5:58,181,025...58,182,969
Ensembl chr 5:58,181,026...58,183,017
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Aspirin inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Aspirin inhibits the reaction [Glucose results in increased expression of CCL2 protein]; Aspirin inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; Aspirin inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]; Aspirin inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Aspirin inhibits the reaction [TNF results in increased secretion of CCL2 protein] CTD PMID:15136050, PMID:16600694, PMID:24211328 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 decreases expression ISO Aspirin results in decreased expression of CCL3 mRNA CTD PMID:21353610 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions EXP Aspirin inhibits the reaction [Glucose results in increased expression of CCN2 mRNA]; Aspirin inhibits the reaction [Streptozocin results in increased expression of CCN2 mRNA] CTD PMID:14586741 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccna2 cyclin A2 multiple interactions ISO Aspirin inhibits the reaction [Methotrexate results in increased expression of CCNA2 protein] CTD PMID:23799623 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 multiple interactions
increases expression
ISO Aspirin inhibits the reaction [troglitazone results in decreased expression of CCNB1 protein]
Aspirin results in increased expression of CCNB1 mRNA
CTD PMID:11906190, PMID:19908241 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
increases expression
ISO
EXP
Aspirin inhibits the reaction [Smoke analog results in increased expression of CCND1 protein]; Aspirin inhibits the reaction [TNF protein results in increased expression of CCND1 protein]; CTNNB1 affects the reaction [Aspirin results in decreased expression of CCND1 protein]
Aspirin results in decreased expression of CCND1 mRNA; Aspirin results in decreased expression of CCND1 protein
Aspirin results in increased expression of CCND1 mRNA
CTD PMID:11313997, PMID:11593435, PMID:12800193, PMID:15489888, PMID:16878161, PMID:17357503, PMID:19207549, PMID:19595669, PMID:19966835, PMID:21721879 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd3 cyclin D3 multiple interactions
decreases expression
ISO Aspirin promotes the reaction [troglitazone results in decreased expression of CCND3 protein]; troglitazone promotes the reaction [Aspirin results in decreased expression of CCND3 protein]
Aspirin results in decreased expression of CCND3 mRNA; Aspirin results in decreased expression of CCND3 protein
CTD PMID:14976132, PMID:19908241 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccne1 cyclin E1 affects expression
decreases expression
EXP
ISO
Aspirin affects the expression of CCNE1 mRNA
Aspirin results in decreased expression of CCNE1 mRNA
CTD PMID:12800193, PMID:20457246 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Ccnj cyclin J increases expression ISO Aspirin results in increased expression of CCNJ mRNA CTD PMID:11906190 NCBI chr 1:259,926,537...259,944,275
Ensembl chr 1:260,093,641...260,111,254
Ensembl chr 1:260,093,641...260,111,254
JBrowse link
G Ccr3 C-C motif chemokine receptor 3 affects response to substance
increases expression
ISO CCR3 gene SNP affects the susceptibility to Aspirin; CCR3 SNP affects the susceptibility to Aspirin
Aspirin results in increased expression of CCR3 mRNA
CTD PMID:18379861, PMID:20022477, PMID:20485159 NCBI chr 8:133,026,539...133,040,999
Ensembl chr 8:133,029,625...133,040,997
JBrowse link
G Cd151 CD151 molecule (Raph blood group) decreases expression ISO Aspirin results in decreased expression of CD151 protein CTD PMID:15381054 NCBI chr 1:214,446,659...214,450,668
Ensembl chr 1:214,009,784...214,013,765
Ensembl chr 1:214,009,784...214,013,765
JBrowse link
G Cd274 CD274 molecule increases expression ISO Aspirin results in increased expression of CD274 mRNA CTD PMID:11906190 NCBI chr 1:247,519,890...247,539,659
Ensembl chr 1:247,519,939...247,537,943
JBrowse link
G Cd36 CD36 molecule decreases expression
increases expression
ISO
EXP
Aspirin results in decreased expression of CD36 protein
Aspirin results in increased expression of CD36 mRNA
CTD PMID:15140583, PMID:15381054, PMID:18222077 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd40lg CD40 ligand decreases expression ISO Aspirin results in decreased expression of CD40LG protein CTD PMID:15140583, PMID:15381054 NCBI chr  X:159,703,703...159,714,886
Ensembl chr  X:159,703,578...159,716,562
JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression
multiple interactions
ISO
EXP
Aspirin results in decreased expression of CD44 protein alternative form
Aspirin results in decreased expression of CD44 mRNA
CTNNB1 affects the reaction [Aspirin results in decreased expression of CD44 protein alternative form]
CTD PMID:12800193, PMID:16878161 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd55 CD55 molecule (Cromer blood group) affects expression EXP Aspirin affects the expression of CD55 mRNA CTD PMID:12800193 NCBI chr13:47,125,156...47,153,557
Ensembl chr13:47,126,741...47,154,292
JBrowse link
G Cd6 Cd6 molecule decreases expression ISO Aspirin results in decreased expression of CD6 mRNA CTD PMID:15928584 NCBI chr 1:226,848,399...226,887,259
Ensembl chr 1:226,848,403...226,887,156
JBrowse link
G Cd74 CD74 molecule decreases expression ISO Aspirin results in decreased expression of CD74 mRNA CTD PMID:15928584 NCBI chr18:56,071,420...56,080,851
Ensembl chr18:56,071,478...56,080,849
JBrowse link
G Cd8a CD8a molecule decreases expression ISO Aspirin results in decreased expression of CD8A mRNA CTD PMID:15928584 NCBI chr 4:99,217,640...99,243,352
Ensembl chr 4:99,239,115...99,243,351
JBrowse link
G Cdc25a cell division cycle 25A decreases expression ISO Aspirin results in decreased expression of CDC25A mRNA CTD PMID:20457246 NCBI chr 8:117,953,223...117,971,552
Ensembl chr 8:117,953,444...117,971,519
JBrowse link
G Cdc37 cell division cycle 37, HSP90 cochaperone decreases expression ISO Aspirin results in decreased expression of CDC37 mRNA CTD PMID:15928584 NCBI chr 8:22,160,922...22,173,797
Ensembl chr 8:22,154,067...22,173,804
JBrowse link
G Cdc42 cell division cycle 42 decreases expression ISO Aspirin results in decreased expression of CDC42 mRNA CTD PMID:14976132 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Cdh1 cadherin 1 affects methylation ISO Aspirin affects the methylation of CDH1 promoter CTD PMID:19184424 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdk19 cyclin-dependent kinase 19 increases expression ISO Aspirin results in increased expression of CDK19 mRNA CTD PMID:11906190 NCBI chr20:45,458,499...45,598,799
Ensembl chr20:45,458,558...45,598,798
JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression
multiple interactions
ISO Aspirin results in decreased expression of CDK2 mRNA; Aspirin results in decreased expression of CDK2 protein
troglitazone promotes the reaction [Aspirin results in decreased expression of CDK2 protein]
CTD PMID:19908241, PMID:20457246 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO Aspirin results in decreased expression of CDK4 mRNA CTD PMID:20457246 NCBI chr 7:70,345,971...70,352,689
Ensembl chr 7:70,349,863...70,352,418
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
decreases expression
increases expression
affects expression
decreases activity
ISO Aspirin inhibits the reaction [Camptothecin results in increased expression of CDKN1A protein]; Aspirin promotes the reaction [romidepsin results in increased expression of CDKN1A protein]; Aspirin results in increased expression of and results in increased phosphorylation of CDKN1A protein; CDKN1A mutant form inhibits the reaction [Aspirin inhibits the reaction [Etoposide results in increased activity of CASP3 protein]]; PTGS1 mutant form inhibits the reaction [Aspirin promotes the reaction [romidepsin results in increased expression of CDKN1A protein]]; wortmannin inhibits the reaction [Aspirin results in increased expression of CDKN1A protein]
Aspirin results in decreased expression of CDKN1A mRNA
Aspirin results in increased expression of CDKN1A mRNA; Aspirin results in increased expression of CDKN1A protein
Aspirin affects the expression of CDKN1A protein
Aspirin results in decreased activity of CDKN1A protein
CTD PMID:14976132, PMID:15190207, PMID:19212664, PMID:19908241, PMID:20404564, PMID:20457246, PMID:21617849 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions
increases expression
ISO [troglitazone co-treated with Aspirin] results in increased expression of CDKN1B protein
Aspirin results in increased expression of CDKN1B protein
CTD PMID:16880202, PMID:19908241 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cds1 CDP-diacylglycerol synthase 1 increases expression EXP Aspirin results in increased expression of CDS1 mRNA CTD PMID:12800193 NCBI chr14:9,396,511...9,456,964
Ensembl chr14:9,396,512...9,456,990
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO Aspirin promotes the reaction [CEBPB protein binds to IL4 promoter polymorphism] CTD PMID:20921925 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cenps centromere protein S increases expression ISO Aspirin results in increased expression of CENPS mRNA CTD PMID:15456535 NCBI chr 5:165,946,106...165,955,723 JBrowse link
G Cep68 centrosomal protein 68 affects response to substance ISO CEP68 SNP affects the susceptibility to Aspirin CTD PMID:21072201 NCBI chr14:104,501,759...104,523,330
Ensembl chr14:104,505,319...104,523,297
JBrowse link
G Ces1d carboxylesterase 1D multiple interactions ISO CES1 protein promotes the reaction [Aspirin results in increased expression of ACACA protein modified form]; CES1 protein promotes the reaction [Aspirin results in increased expression of PRKAA1 protein modified form] CTD PMID:25743752 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Ces2c carboxylesterase 2C increases hydrolysis ISO CES2C protein results in increased hydrolysis of Aspirin CTD PMID:22513142 NCBI chr 1:282,640,752...282,648,319
Ensembl chr 1:282,638,017...282,702,424
JBrowse link
G Ces2h carboxylesterase 2H affects hydrolysis
increases hydrolysis
ISO CES2 protein affects the hydrolysis of Aspirin
CES2 protein results in increased hydrolysis of Aspirin
CTD PMID:9300133, PMID:18983829 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression
multiple interactions
ISO Aspirin results in increased expression of CFLAR mRNA
Aspirin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CFLAR protein]
CTD PMID:20457246, PMID:25449198 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Chd2 chromodomain helicase DNA binding protein 2 increases expression ISO Aspirin results in increased expression of CHD2 mRNA CTD PMID:15928584 NCBI chr 1:134,757,934...134,873,053
Ensembl chr 1:134,757,934...134,871,167
JBrowse link
G Chek2 checkpoint kinase 2 increases expression ISO Aspirin results in increased expression of CHEK2 mRNA CTD PMID:20457246 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Chmp1a charged multivesicular body protein 1A decreases expression ISO Aspirin results in decreased expression of CHMP1A mRNA CTD PMID:14976132 NCBI chr19:56,001,724...56,010,004
Ensembl chr19:56,001,724...56,010,004
JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions
decreases phosphorylation
ISO
EXP
Aspirin inhibits the reaction [TNF protein results in increased activity of CHUK protein]
Aspirin results in decreased phosphorylation of CHUK protein
CTD PMID:15489888, PMID:16310244 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169
JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B increases expression ISO Aspirin results in increased expression of CKS1B mRNA CTD PMID:14976132 NCBI chr 2:188,740,564...188,745,144
Ensembl chr 2:188,740,573...188,745,144
JBrowse link
G Cldn7 claudin 7 increases expression EXP Aspirin results in increased expression of CLDN7 mRNA CTD PMID:12800193 NCBI chr10:56,576,326...56,578,632
Ensembl chr10:56,576,428...56,578,626
JBrowse link
G Clip3 CAP-GLY domain containing linker protein 3 increases expression ISO Aspirin results in increased expression of CLIP3 mRNA CTD PMID:11906190 NCBI chr 1:88,750,453...88,766,453
Ensembl chr 1:90,962,707...90,978,907
JBrowse link
G Clk2 CDC-like kinase 2 decreases expression ISO Aspirin results in decreased expression of CLK2 mRNA CTD PMID:15928584 NCBI chr 2:188,476,789...188,488,809
Ensembl chr 2:188,476,820...188,496,191
JBrowse link
G Clk3 CDC-like kinase 3 decreases expression ISO Aspirin results in decreased expression of CLK3 mRNA CTD PMID:15928584 NCBI chr 8:62,528,135...62,543,550
Ensembl chr 8:62,528,225...62,542,622
JBrowse link
G Col26a1 collagen type XXVI alpha 1 chain affects response to substance ISO COL26A1 polymorphism affects the susceptibility to Aspirin CTD PMID:21086123 NCBI chr12:22,834,866...22,980,603
Ensembl chr12:22,835,019...22,980,603
JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression ISO Aspirin results in decreased expression of COL3A1 mRNA CTD PMID:15456535 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Col7a1 collagen type VII alpha 1 chain decreases expression ISO Aspirin results in decreased expression of COL7A1 mRNA CTD PMID:15928584 NCBI chr 8:117,694,441...117,726,844
Ensembl chr 8:117,694,605...117,726,844
JBrowse link
G Cpne1 copine 1 increases expression ISO Aspirin results in increased expression of CPNE1 mRNA CTD PMID:11906190 NCBI chr 3:151,617,733...151,625,448
NCBI chr 3:152,150,143...152,192,936
Ensembl chr 3:151,616,037...151,625,644
Ensembl chr 3:151,616,037...151,625,644
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO Aspirin results in increased expression of CPT1A mRNA; Aspirin results in increased expression of CPT1A protein CTD PMID:25743752 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cracr2b calcium release activated channel regulator 2B increases expression ISO Aspirin results in increased expression of CRACR2B mRNA CTD PMID:11906190 NCBI chr 1:214,439,810...214,445,876
Ensembl chr 1:214,440,503...214,445,874
JBrowse link
G Crebbp CREB binding protein increases expression ISO Aspirin results in increased expression of CREBBP mRNA CTD PMID:11906190 NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039
JBrowse link
G Csf3r colony stimulating factor 3 receptor decreases expression ISO Aspirin results in decreased expression of CSF3R mRNA CTD PMID:15928584 NCBI chr 5:144,031,353...144,051,966
Ensembl chr 5:144,031,402...144,051,600
JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 increases expression
decreases expression
ISO Aspirin results in increased expression of CSNK2A1 mRNA
Aspirin results in decreased expression of CSNK2A1 mRNA
CTD PMID:11906190 NCBI chr 3:147,713,808...147,760,375
Ensembl chr 3:147,713,821...147,757,862
JBrowse link
G Csta cystatin A increases expression ISO Aspirin results in increased expression of CSTA mRNA CTD PMID:15456535, PMID:15928584 NCBI chr11:67,555,792...67,566,980
Ensembl chr11:67,555,658...67,566,972
JBrowse link
G Ctnnb1 catenin beta 1 increases phosphorylation
decreases localization
multiple interactions
increases ubiquitination
ISO Aspirin results in increased phosphorylation of CTNNB1 protein
Aspirin results in decreased localization of CTNNB1 protein
benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Aspirin results in increased ubiquitination of CTNNB1 protein]; CTNNB1 affects the reaction [Aspirin results in decreased expression of CCND1 protein]; CTNNB1 affects the reaction [Aspirin results in decreased expression of CD44 protein alternative form]; CTNNB1 affects the reaction [Aspirin results in decreased expression of CMET protein]; CTNNB1 affects the reaction [Aspirin results in decreased expression of MYC protein]; Lithium Chloride inhibits the reaction [Aspirin results in increased phosphorylation of CTNNB1 protein]
CTD PMID:12813129, PMID:16878161, PMID:17357503 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctsb cathepsin B decreases expression ISO Aspirin results in decreased expression of CTSB mRNA CTD PMID:21353610 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 multiple interactions
decreases expression
ISO Aspirin inhibits the reaction [TNF results in increased expression of CX3CL1 mRNA]; Aspirin inhibits the reaction [TNF results in increased expression of CX3CL1 protein]
Aspirin results in decreased expression of CX3CL1 mRNA; Aspirin results in decreased expression of CX3CL1 protein
CTD PMID:19493461, PMID:19997773 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions ISO Aspirin inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY analog results in increased secretion of CXCL1 protein]; Aspirin promotes the reaction [IL1A results in increased expression of CXCL1 mRNA] CTD PMID:14742690, PMID:17303692 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO Aspirin inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY analog results in increased secretion of CXCL1 protein]; Aspirin promotes the reaction [IL1A results in increased expression of CXCL1 mRNA] CTD PMID:14742690, PMID:17303692 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 increases expression EXP Aspirin results in increased expression of CXCL5 mRNA CTD PMID:12800193 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
JBrowse link
G Cyc1 cytochrome c-1 increases expression EXP Aspirin results in increased expression of CYC1 mRNA CTD PMID:8554334 NCBI chr 7:117,409,576...117,411,953
Ensembl chr 7:117,409,576...117,411,953
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP Aspirin results in increased expression of CYP2E1 mRNA CTD PMID:11752103 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cysltr1 cysteinyl leukotriene receptor 1 increases expression
multiple interactions
affects response to substance
ISO Aspirin results in increased expression of CYSLTR1 mRNA
Aspirin inhibits the reaction [IL4 results in increased expression of CYSLTR1 mRNA]
CYSLTR1 gene SNP affects the susceptibility to Aspirin; CYSLTR1 SNP affects the susceptibility to Aspirin
CTD PMID:16630147, PMID:17641958, PMID:18379861, PMID:19767084, PMID:20485159 NCBI chr  X:77,671,028...77,700,491
Ensembl chr  X:77,674,150...77,700,269
JBrowse link
G Cysltr2 cysteinyl leukotriene receptor 2 affects response to substance ISO CYSLTR2 gene SNP affects the susceptibility to Aspirin; CYSLTR2 polymorphism affects the susceptibility to Aspirin CTD PMID:15970796, PMID:20485159 NCBI chr15:54,903,290...54,941,742
Ensembl chr15:54,905,274...54,906,203
JBrowse link
G Dap death-associated protein decreases expression ISO Aspirin results in decreased expression of DAP mRNA CTD PMID:15928584 NCBI chr 2:84,275,884...84,328,998
Ensembl chr 2:84,275,884...84,328,998
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO
EXP
Aspirin results in increased expression of DDIT3 mRNA CTD PMID:12800193, PMID:14976132 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddx18 DEAD-box helicase 18 decreases expression ISO Aspirin results in decreased expression of DDX18 mRNA CTD PMID:11906190 NCBI chr13:37,522,558...37,536,066
Ensembl chr13:37,522,561...37,536,066
JBrowse link
G Ddx5 DEAD-box helicase 5 increases expression ISO Aspirin results in increased expression of DDX5 mRNA CTD PMID:15928584 NCBI chr10:94,979,759...94,988,461
Ensembl chr10:94,980,928...94,988,461
JBrowse link
G Defa5 defensin alpha 5 increases expression EXP Aspirin results in increased expression of DEFA5 mRNA CTD PMID:20043115 NCBI chr16:75,338,050...75,340,401
Ensembl chr16:75,338,052...75,340,360
JBrowse link
G Dek DEK proto-oncogene increases expression ISO Aspirin results in increased expression of DEK mRNA CTD PMID:15928584 NCBI chr17:17,965,872...17,987,836
Ensembl chr17:17,965,881...17,987,834
JBrowse link
G Dennd5a DENN domain containing 5A increases expression ISO Aspirin results in increased expression of DENND5A mRNA CTD PMID:11906190 NCBI chr 1:174,524,047...174,588,553
Ensembl chr 1:174,524,047...174,588,529
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein decreases expression ISO Aspirin results in decreased expression of DIABLO protein CTD PMID:15976387 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase decreases expression ISO Aspirin results in decreased expression of DLST mRNA CTD PMID:11906190 NCBI chr 6:108,936,534...108,961,322
Ensembl chr 6:108,936,664...108,959,803
JBrowse link
G Dusp1 dual specificity phosphatase 1 affects expression EXP Aspirin affects the expression of DUSP1 mRNA CTD PMID:12800193 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp5 dual specificity phosphatase 5 affects expression EXP Aspirin affects the expression of DUSP5 mRNA CTD PMID:12800193 NCBI chr 1:274,245,184...274,258,595
Ensembl chr 1:274,245,184...274,258,595
JBrowse link
G Dusp6 dual specificity phosphatase 6 increases expression EXP Aspirin results in increased expression of DUSP6 mRNA CTD PMID:12800193 NCBI chr 7:41,475,163...41,479,393
Ensembl chr 7:41,475,163...41,479,392
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions
decreases expression
ISO [troglitazone co-treated with Aspirin] results in decreased expression of E2F1 protein; Aspirin inhibits the reaction [E2F1 protein binds to BIRC5 promoter]
Aspirin results in decreased expression of E2F1 mRNA
CTD PMID:17848598, PMID:19908241, PMID:20457246 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Ednrb endothelin receptor type B multiple interactions ISO Aspirin inhibits the reaction [IL1B results in increased activity of EDNRB] CTD PMID:12126971 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 increases expression ISO Aspirin results in increased expression of EEF1A1 mRNA CTD PMID:14976132 NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818
JBrowse link
G Egfr epidermal growth factor receptor increases expression ISO Aspirin results in increased expression of EGFR mRNA CTD PMID:15456535 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egr1 early growth response 1 increases expression EXP Aspirin results in increased expression of EGR1 mRNA CTD PMID:12800193 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Egr4 early growth response 4 decreases expression ISO Aspirin results in decreased expression of EGR4 mRNA CTD PMID:11906190 NCBI chr 4:117,293,620...117,296,082
Ensembl chr 4:117,293,620...117,296,082
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase decreases expression ISO Aspirin results in decreased expression of EHHADH mRNA CTD PMID:27089845 NCBI chr11:82,945,104...82,978,364
Ensembl chr11:82,945,104...82,978,364
JBrowse link
G Ehmt2 euchromatic histone lysine methyltransferase 2 increases expression ISO Aspirin results in increased expression of EHMT2 mRNA CTD PMID:11906190 NCBI chr20:4,576,033...4,592,980
Ensembl chr20:4,576,057...4,592,980
JBrowse link
G Eif2s2 eukaryotic translation initiation factor 2 subunit beta increases expression ISO Aspirin results in increased expression of EIF2S2 mRNA CTD PMID:15928584 NCBI chr 3:150,391,455...150,412,179
Ensembl chr 3:150,391,460...150,412,179
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO Aspirin results in decreased phosphorylation of and results in increased expression of EIF4EBP1 protein CTD PMID:23363784 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Elf4 E74 like ETS transcription factor 4 decreases expression ISO Aspirin results in decreased expression of ELF4 mRNA CTD PMID:15928584 NCBI chr  X:135,239,626...135,284,330
Ensembl chr  X:135,240,451...135,250,519
JBrowse link
G Elovl5 ELOVL fatty acid elongase 5 increases expression
decreases expression
ISO Aspirin results in increased expression of ELOVL5 mRNA
Aspirin results in decreased expression of ELOVL5 mRNA
CTD PMID:11906190, PMID:15928584 NCBI chr 8:85,220,941...85,287,449
Ensembl chr 8:85,259,982...85,285,983
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 decreases expression EXP Aspirin results in decreased expression of ENPP2 mRNA CTD PMID:12800193 NCBI chr 7:94,479,931...94,563,086
Ensembl chr 7:94,480,396...94,563,001
JBrowse link
G Entpd2 ectonucleoside triphosphate diphosphohydrolase 2 increases expression EXP Aspirin results in increased expression of ENTPD2 mRNA CTD PMID:12800193 NCBI chr 3:2,617,795...2,623,818
Ensembl chr 3:2,617,805...2,623,445
JBrowse link
G Epdr1 ependymin related 1 decreases expression ISO Aspirin results in decreased expression of EPDR1 mRNA CTD PMID:20457246 NCBI chr17:47,397,558...47,422,183
Ensembl chr17:47,397,558...47,422,182
JBrowse link
G Ephx2 epoxide hydrolase 2 multiple interactions ISO Aspirin promotes the reaction [EPHX2 gene mutant form results in decreased susceptibility to Lipopolysaccharides]; EPHX2 gene mutant form promotes the reaction [[Lipopolysaccharides co-treated with Aspirin] results in decreased abundance of 11,12-dihydroxyeicosatrienoic acid]; EPHX2 gene mutant form promotes the reaction [[Lipopolysaccharides co-treated with Aspirin] results in decreased abundance of 14,15-dihydroxyeicosatrienoic acid]; EPHX2 gene mutant form promotes the reaction [Aspirin inhibits the reaction [Lipopolysaccharides results in increased abundance of Dinoprostone]]; EPHX2 gene mutant form promotes the reaction [Aspirin inhibits the reaction [Lipopolysaccharides results in increased abundance of Prostaglandin D2]] CTD PMID:19896470 NCBI chr15:42,757,241...42,794,211
Ensembl chr15:42,757,235...42,794,279
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases expression
increases expression
ISO Aspirin results in decreased expression of ERBB2 mRNA; Aspirin results in decreased expression of ERBB2 protein
Aspirin results in increased expression of ERBB2 mRNA
CTD PMID:19424877, PMID:20457246 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Erbin erbb2 interacting protein increases expression ISO Aspirin results in increased expression of ERBIN mRNA CTD PMID:15928584 NCBI chr 2:33,880,860...33,952,806
Ensembl chr 2:33,881,024...33,920,837
JBrowse link
G Ercc5 ERCC excision repair 5, endonuclease increases expression ISO Aspirin results in increased expression of ERCC5 mRNA CTD PMID:11906190 NCBI chr 9:50,928,847...50,970,962
Ensembl chr 9:50,925,619...50,970,955
JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor decreases expression ISO Aspirin results in decreased expression of ETS2 mRNA CTD PMID:20457246 NCBI chr11:36,075,709...36,092,495
Ensembl chr11:36,075,709...36,092,495
JBrowse link
G Evi2b ecotropic viral integration site 2B increases expression ISO Aspirin results in increased expression of EVI2B mRNA CTD PMID:15928584 NCBI chr10:66,856,980...66,858,598
Ensembl chr10:66,856,980...66,858,598
JBrowse link
G Ezr ezrin decreases expression ISO Aspirin results in decreased expression of EZR mRNA CTD PMID:14976132 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412
JBrowse link
G F2 coagulation factor II affects cleavage
multiple interactions
ISO Aspirin affects the cleavage of F2 protein
ITGB3 polymorphism affects the reaction [Aspirin affects the cleavage of F2 protein]
CTD PMID:16675000 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G F2r coagulation factor II (thrombin) receptor decreases expression ISO Aspirin results in decreased expression of F2R protein CTD PMID:15140583, PMID:15381054 NCBI chr 2:26,118,760...26,135,340
Ensembl chr 2:26,118,760...26,135,340
JBrowse link
G Fas Fas cell surface death receptor affects expression
multiple interactions
increases expression
ISO
EXP
Aspirin affects the expression of FAS protein
Aspirin inhibits the reaction [Methotrexate results in increased expression of FAS protein]
Aspirin results in increased expression of FAS mRNA
Aspirin inhibits the reaction [Azoxymethane results in increased expression of FAS mRNA]
CTD PMID:15200494, PMID:20043115, PMID:20457246, PMID:23799623 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand multiple interactions EXP Aspirin inhibits the reaction [Azoxymethane results in increased expression of FASLG mRNA] CTD PMID:20043115 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fat3 FAT atypical cadherin 3 increases expression ISO Aspirin results in increased expression of FAT3 mRNA CTD PMID:11906190 NCBI chr 8:14,417,039...15,011,596
Ensembl chr 8:14,417,584...14,880,644
JBrowse link
G Fbxl3 F-box and leucine-rich repeat protein 3 increases expression ISO Aspirin results in increased expression of FBXL3 mRNA CTD PMID:15928584 NCBI chr15:93,647,307...93,667,395
Ensembl chr15:93,647,310...93,667,395
JBrowse link
G Fbxo11 F-box protein 11 increases expression ISO Aspirin results in increased expression of FBXO11 mRNA CTD PMID:15928584 NCBI chr 6:11,662,356...11,737,427
Ensembl chr 6:11,662,356...11,686,682
JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia affects response to substance
multiple interactions
ISO FCER1A gene SNP affects the susceptibility to Aspirin; FCER1A polymorphism affects the susceptibility to Aspirin
Aspirin inhibits the reaction [IL4 results in increased expression of FCER1A mRNA]
CTD PMID:17125826, PMID:19767084, PMID:20485159 NCBI chr13:91,727,253...91,737,106
Ensembl chr13:91,730,925...91,737,053
JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig decreases expression
affects response to substance
ISO Aspirin results in decreased expression of FCER1G mRNA
FCER1G SNP affects the susceptibility to Aspirin
CTD PMID:15928584, PMID:18534082, PMID:18595682 NCBI chr13:89,601,894...89,606,326
Ensembl chr13:89,601,896...89,606,326
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 increases expression EXP Aspirin results in increased expression of FDFT1 mRNA CTD PMID:12800193 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fer FER tyrosine kinase decreases expression ISO Aspirin results in decreased expression of FER mRNA CTD PMID:15456535 NCBI chr 9:111,557,804...111,868,583
Ensembl chr 9:111,597,037...111,862,670
JBrowse link
G Fga fibrinogen alpha chain decreases secretion
multiple interactions
ISO Aspirin results in decreased secretion of FGA protein
Aspirin inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY analog results in increased secretion of FGA protein]; Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of FGA protein]
CTD PMID:17303692 NCBI chr 2:181,997,562...182,013,726
Ensembl chr 2:182,006,242...182,013,763
JBrowse link
G Fgb fibrinogen beta chain multiple interactions
decreases secretion
ISO Aspirin inhibits the reaction [Adenosine Diphosphate results in decreased secretion of FGB protein]; Aspirin inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY analog results in increased secretion of FGB protein]
Aspirin results in decreased secretion of FGB protein
CTD PMID:17303692 NCBI chr 2:182,028,044...182,035,026
Ensembl chr 2:182,027,115...182,038,178
JBrowse link
G Fgg fibrinogen gamma chain multiple interactions ISO Aspirin inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY analog results in increased secretion of FGG protein]; Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of FGG protein] CTD PMID:17303692 NCBI chr 2:181,987,080...181,994,523
Ensembl chr 2:181,987,217...181,994,514
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase decreases expression ISO Aspirin results in decreased expression of FGR mRNA CTD PMID:15928584 NCBI chr 5:151,172,189...151,199,746
Ensembl chr 5:151,172,206...151,199,745
JBrowse link
G Flii FLII, actin remodeling protein decreases expression ISO Aspirin results in decreased expression of FLII mRNA CTD PMID:15928584 NCBI chr10:46,955,460...46,969,468
Ensembl chr10:46,955,487...46,969,406
JBrowse link
G Flot2 flotillin 2 decreases expression ISO Aspirin results in decreased expression of FLOT2 mRNA CTD PMID:15928584 NCBI chr10:65,304,901...65,329,332
Ensembl chr10:65,304,902...65,329,312
JBrowse link
G Fn1 fibronectin 1 multiple interactions EXP Aspirin inhibits the reaction [Streptozocin results in increased expression of FN1] CTD PMID:14586741 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression
decreases expression
EXP
ISO
Aspirin results in increased expression of FOS mRNA
Aspirin results in decreased expression of FOS mRNA
CTD PMID:12800193, PMID:20457246 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Aspirin results in decreased expression of FOSB mRNA CTD PMID:15928584 NCBI chr 1:80,214,691...80,221,417
Ensembl chr 1:80,214,494...80,221,710
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions
decreases expression
increases expression
ISO
EXP
Aspirin promotes the reaction [FOSL1 protein binds to PLAUR promoter]
Aspirin results in decreased expression of FOSL1 mRNA; Aspirin results in decreased expression of FOSL1 protein
Aspirin results in increased expression of FOSL1 mRNA
CTD PMID:12800193, PMID:16893520, PMID:21721879 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression EXP Aspirin results in increased expression of FOSL2 mRNA CTD PMID:12800193 NCBI chr 6:25,598,936...25,616,995
Ensembl chr 6:25,598,936...25,616,995
JBrowse link
G Fpr1 formyl peptide receptor 1 decreases expression ISO Aspirin results in decreased expression of FPR1 mRNA CTD PMID:15928584 NCBI chr 1:59,759,025...59,767,258
Ensembl chr 1:59,765,835...59,767,042
JBrowse link
G Fpr2 formyl peptide receptor 2 increases expression
multiple interactions
ISO Aspirin results in increased expression of FPR2
[Aspirin results in increased abundance of lipoxin A4] which results in increased expression of FPR2
CTD PMID:19597002 NCBI chr 1:59,800,558...59,809,507
Ensembl chr 1:59,800,984...59,802,401
JBrowse link
G Fsip1 fibrous sheath interacting protein 1 affects response to substance ISO FSIP1 SNP affects the susceptibility to Aspirin CTD PMID:20513247 NCBI chr 3:109,877,943...110,021,186
Ensembl chr 3:109,969,152...110,021,149
JBrowse link
G Fst follistatin affects expression EXP Aspirin affects the expression of FST mRNA CTD PMID:12800193 NCBI chr 2:46,537,589...46,544,813
Ensembl chr 2:46,538,700...46,544,457
JBrowse link
G Furin furin (paired basic amino acid cleaving enzyme) decreases expression ISO Aspirin results in decreased expression of FURIN mRNA CTD PMID:15928584 NCBI chr 1:142,185,092...142,198,167
Ensembl chr 1:142,185,094...142,197,182
JBrowse link
G Fxr2 FMR1 autosomal homolog 2 decreases expression ISO Aspirin results in decreased expression of FXR2 mRNA CTD PMID:15456535 NCBI chr10:56,237,814...56,257,877
Ensembl chr10:56,237,755...56,257,890
JBrowse link
G G0s2 G0/G1switch 2 increases expression EXP Aspirin results in increased expression of G0S2 mRNA CTD PMID:12800193 NCBI chr13:112,004,140...112,005,052
Ensembl chr13:112,004,140...112,005,052
JBrowse link
G G6pc3 glucose 6 phosphatase catalytic subunit 3 increases expression ISO Aspirin results in increased expression of G6PC3 mRNA CTD PMID:11906190 NCBI chr10:90,134,193...90,138,425
Ensembl chr10:90,134,193...90,138,425
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases response to substance
decreases activity
ISO G6PD results in decreased susceptibility to Aspirin
Aspirin results in decreased activity of G6PD protein mutant form
CTD PMID:5432368 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gabarap GABA type A receptor-associated protein decreases expression ISO Aspirin results in decreased expression of GABARAP mRNA CTD PMID:15928584 NCBI chr10:56,601,288...56,604,223
Ensembl chr10:56,601,288...56,604,221
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression
increases expression
EXP
ISO
Aspirin results in decreased expression of GADD45A mRNA
Aspirin results in increased expression of GADD45A mRNA
CTD PMID:12800193, PMID:20514442 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gas6 growth arrest specific 6 affects response to substance ISO GAS6 protein affects the susceptibility to Aspirin CTD PMID:16999853 NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757
JBrowse link
G Gast gastrin multiple interactions EXP [lipopolysaccharide, Helicobacter pylori co-treated with Aspirin] results in increased expression of GAST protein CTD PMID:15024038 NCBI chr10:88,245,532...88,248,485
Ensembl chr10:88,245,532...88,248,484
JBrowse link
G Gatd3a glutamine amidotransferase like class 1 domain containing 3A increases expression ISO Aspirin results in increased expression of GATD3A mRNA CTD PMID:11906190 NCBI chr20:11,244,353...11,252,450
Ensembl chr20:11,244,353...11,252,449
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Aspirin results in increased expression of GDF15 mRNA; Aspirin results in increased expression of GDF15 protein CTD PMID:14976132, PMID:15180942 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression
increases expression
ISO
EXP
Aspirin results in decreased expression of GFAP mRNA; Aspirin results in decreased expression of GFAP protein
Aspirin results in increased expression of GFAP mRNA
CTD PMID:16516312, PMID:21353610, PMID:22954530 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gfra3 GDNF family receptor alpha 3 increases expression ISO Aspirin results in increased expression of GFRA3 mRNA CTD PMID:15928584 NCBI chr18:27,491,860...27,520,133
Ensembl chr18:27,491,845...27,520,295
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 decreases activity EXP Aspirin analog results in decreased activity of GGT1 protein CTD PMID:20171274 NCBI chr20:14,019,723...14,045,781
Ensembl chr20:14,019,723...14,025,068
JBrowse link
G Ghitm growth hormone inducible transmembrane protein increases expression ISO Aspirin results in increased expression of GHITM mRNA CTD PMID:15928584 NCBI chr16:14,370,269...14,382,647
Ensembl chr16:14,371,531...14,382,641
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP Aspirin results in decreased expression of GJA1 mRNA CTD PMID:12800193 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gkn1 gastrokine 1 affects expression ISO Aspirin affects the expression of GKN1 mRNA; Aspirin affects the expression of GKN1 protein CTD PMID:19145733 NCBI chr 4:119,143,070...119,148,358
Ensembl chr 4:119,143,070...119,148,358
JBrowse link
G Gnb2 G protein subunit beta 2 decreases expression ISO Aspirin results in decreased expression of GNB2 mRNA CTD PMID:15928584 NCBI chr12:22,229,079...22,234,096
Ensembl chr12:22,229,079...22,234,096
JBrowse link
G Gp1ba glycoprotein Ib platelet subunit alpha decreases response to substance
increases response to substance
affects response to substance
ISO GP1BA SNP results in decreased susceptibility to Aspirin
GP1BA polymorphism results in increased susceptibility to Aspirin
GP1BA polymorphism affects the susceptibility to Aspirin
CTD PMID:17245331, PMID:17630485, PMID:19250145 NCBI chr10:57,260,680...57,263,546
Ensembl chr10:57,260,680...57,263,546
JBrowse link
G Gp6 glycoprotein VI decreases response to substance ISO GP6 gene polymorphism results in decreased susceptibility to Aspirin CTD PMID:16493486 NCBI chr 1:72,994,977...73,064,639
Ensembl chr 1:73,040,901...73,064,641
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases expression
EXP fucoidan inhibits the reaction [Aspirin results in increased expression of GPT protein] CTD PMID:19788892 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression ISO Aspirin results in decreased expression of GPX1 mRNA CTD PMID:21353610 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta decreases phosphorylation
increases phosphorylation
decreases activity
ISO
EXP
Aspirin results in decreased phosphorylation of GSK3B protein
Aspirin results in increased phosphorylation of GSK3B protein
Aspirin results in decreased activity of GSK3B protein
CTD PMID:11593435, PMID:12813129, PMID:19966835 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsn gelsolin affects expression EXP Aspirin affects the expression of GSN protein CTD PMID:23533533 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 affects binding EXP Aspirin binds to GSTA2 protein CTD PMID:15236443 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gstm1 glutathione S-transferase mu 1 affects response to substance ISO GSTM1 mutant form affects the susceptibility to Aspirin CTD PMID:16433794 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gsto1 glutathione S-transferase omega 1 decreases expression ISO Aspirin results in decreased expression of GSTO1 mRNA CTD PMID:14976132 NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387
JBrowse link
G Gstt1 glutathione S-transferase theta 1 increases expression EXP Aspirin results in increased expression of GSTT1 protein CTD PMID:9729437 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Gstt2 glutathione S-transferase, theta 2 increases expression EXP Aspirin results in increased expression of GSTT2 protein CTD PMID:9729437 NCBI chr20:13,760,810...13,764,481
Ensembl chr20:13,760,810...13,764,475
JBrowse link
G Gtf2i general transcription factor II I decreases expression ISO Aspirin results in decreased expression of GTF2I mRNA CTD PMID:11906190 NCBI chr12:25,410,804...25,487,970
Ensembl chr12:25,411,207...25,488,156
JBrowse link
G Gtpbp2 GTP binding protein 2 decreases expression ISO Aspirin results in decreased expression of GTPBP2 mRNA CTD PMID:15928584 NCBI chr 9:17,198,957...17,208,456
Ensembl chr 9:17,198,957...17,209,220
JBrowse link
G Guk1 guanylate kinase 1 decreases expression ISO Aspirin results in decreased expression of GUK1 mRNA CTD PMID:15928584 NCBI chr10:45,535,617...45,552,455
Ensembl chr10:45,535,627...45,543,897
JBrowse link
G Gzma granzyme A decreases expression ISO Aspirin results in decreased expression of GZMA mRNA CTD PMID:20457246 NCBI chr 2:44,968,846...44,981,436
Ensembl chr 2:44,968,765...44,981,458
JBrowse link
G H2ax H2A.X variant histone decreases expression ISO Aspirin results in decreased expression of H2AX protein CTD PMID:23363784 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions
increases expression
EXP apple polyphenol extract inhibits the reaction [Aspirin results in increased expression of HBEGF mRNA]; apple polyphenol extract inhibits the reaction [Aspirin results in increased expression of HBEGF protein]
Aspirin results in increased expression of HBEGF mRNA; Aspirin results in increased expression of HBEGF protein
CTD PMID:18482463 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase decreases expression ISO Aspirin results in decreased expression of HCK mRNA CTD PMID:15928584 NCBI chr 3:148,579,917...148,623,026
Ensembl chr 3:148,579,920...148,623,033
JBrowse link
G Hcls1 hematopoietic cell specific Lyn substrate 1 decreases expression ISO Aspirin results in decreased expression of HCLS1 mRNA CTD PMID:15928584 NCBI chr11:66,736,966...66,759,402
Ensembl chr11:66,736,966...66,759,402
JBrowse link
G Hdac1 histone deacetylase 1 increases expression ISO Aspirin results in increased expression of HDAC1 mRNA CTD PMID:15456535 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hdac3 histone deacetylase 3 multiple interactions ISO HDAC3 inhibits the reaction [Aspirin results in increased acetylation of and results in increased activity of NOS3 protein]; HDAC3 protein inhibits the reaction [Aspirin promotes the reaction [NOS3 protein binds to CALM1 protein]] CTD PMID:20705923 NCBI chr18:31,073,057...31,094,347
Ensembl chr18:31,073,058...31,094,303
JBrowse link
G Hdac4 histone deacetylase 4 increases expression ISO Aspirin results in increased expression of HDAC4 mRNA CTD PMID:15928584 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715
JBrowse link
G Hdgf heparin binding growth factor decreases expression ISO Aspirin results in decreased expression of HDGF mRNA CTD PMID:15928584 NCBI chr 2:187,274,898...187,284,670
Ensembl chr 2:187,275,120...187,284,281
JBrowse link
G Hgf hepatocyte growth factor multiple interactions ISO Aspirin inhibits the reaction [HGF results in increased activity of MAPK1 protein]; Aspirin inhibits the reaction [HGF results in increased activity of MAPK3 protein]; Aspirin inhibits the reaction [HGF results in increased expression of MMP9] CTD PMID:11981761 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hlcs holocarboxylase synthetase increases expression ISO Aspirin results in increased expression of HLCS mRNA CTD PMID:11906190 NCBI chr11:34,357,372...34,537,798
Ensembl chr11:34,352,287...34,526,931
JBrowse link
G Hmmr hyaluronan-mediated motility receptor increases expression ISO Aspirin results in increased expression of HMMR mRNA CTD PMID:11906190 NCBI chr10:25,861,490...25,890,639
Ensembl chr10:25,861,490...25,890,639
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO
EXP
Aspirin results in increased expression of HMOX1
Aspirin analog results in increased expression of HMOX1 mRNA
CTD PMID:15901601, PMID:19100325 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnf1a HNF1 homeobox A decreases expression EXP Aspirin results in decreased expression of HNF1A mRNA CTD PMID:12800193 NCBI chr12:47,407,811...47,433,342
Ensembl chr12:47,407,811...47,433,342
JBrowse link
G Hnmt histamine N-methyltransferase affects response to substance ISO HNMT gene SNP affects the susceptibility to Aspirin CTD PMID:20485159 NCBI chr 3:905,111...937,038
Ensembl chr 3:904,765...937,102
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 decreases expression EXP Aspirin results in decreased expression of HNRNPA1 mRNA CTD PMID:12800193 NCBI chr 7:144,865,302...144,871,592
Ensembl chr 7:144,865,608...144,871,585
JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C decreases expression EXP Aspirin results in decreased expression of HNRNPC mRNA CTD PMID:12800193 NCBI chr15:28,486,605...28,517,353
Ensembl chr15:28,486,617...28,517,353
JBrowse link
G Hnrnpdl heterogeneous nuclear ribonucleoprotein D-like decreases expression ISO Aspirin results in decreased expression of HNRNPDL mRNA CTD PMID:15456535 NCBI chr14:11,199,114...11,204,670
Ensembl chr14:11,198,896...11,202,669
JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U increases expression ISO Aspirin results in increased expression of HNRNPU mRNA CTD PMID:15928584 NCBI chr13:96,222,093...96,238,845
Ensembl chr13:96,225,912...96,238,572
JBrowse link
G Hnrnpul1 heterogeneous nuclear ribonucleoprotein U-like 1 decreases expression ISO Aspirin results in decreased expression of HNRNPUL1 mRNA CTD PMID:15928584 NCBI chr 1:82,512,745...82,548,446
Ensembl chr 1:82,512,745...82,546,937
JBrowse link
G Hsf1 heat shock transcription factor 1 increases activity ISO Aspirin results in increased activity of HSF1 protein CTD PMID:10328874 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression ISO Aspirin results in increased expression of HSPA1A mRNA CTD PMID:15456535 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO Aspirin results in decreased expression of HSPA5 mRNA CTD PMID:14976132 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression EXP Aspirin results in increased expression of HSPB1 mRNA CTD PMID:12800193 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Iars1 isoleucyl-tRNA synthetase 1 decreases expression ISO Aspirin results in decreased expression of IARS1 mRNA CTD PMID:11906190 NCBI chr17:15,356,016...15,402,680
Ensembl chr17:15,355,529...15,402,649
JBrowse link
G Icam1 intercellular adhesion molecule 1 decreases expression
multiple interactions
ISO
EXP
Aspirin results in decreased expression of ICAM1 mRNA; Aspirin results in decreased expression of ICAM1 protein
Aspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of ICAM1 protein]; Celecoxib inhibits the reaction [Aspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of ICAM1 protein]]
CTD PMID:14762100, PMID:16310244, PMID:18059344 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Id2 inhibitor of DNA binding 2 affects expression EXP Aspirin affects the expression of ID2 mRNA CTD PMID:12800193 NCBI chr 6:44,360,077...44,361,908
Ensembl chr 6:44,348,501...44,363,915
JBrowse link
G Ido1 indoleamine 2,3-dioxygenase 1 affects response to substance ISO IDO1 affects the susceptibility to Aspirin CTD PMID:19489917 NCBI chr16:72,216,326...72,228,098
Ensembl chr16:72,216,326...72,228,098
JBrowse link
G Ifi30 IFI30, lysosomal thiol reductase decreases expression ISO Aspirin results in decreased expression of IFI30 mRNA CTD PMID:15928584 NCBI chr16:20,426,566...20,430,772
Ensembl chr16:20,426,566...20,430,752
JBrowse link
G Ifng interferon gamma multiple interactions
increases expression
ISO
EXP
Aspirin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased secretion of [IL12A protein binds to IL12B protein]]; Aspirin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IFNG protein]
Aspirin results in increased expression of IFNG protein
fucoidan promotes the reaction [Aspirin results in increased expression of IFNG protein]
Aspirin inhibits the reaction [Acetaminophen results in increased expression of IFNG mRNA]
CTD PMID:15379866, PMID:19164858, PMID:19788892 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Ift27 intraflagellar transport 27 increases expression ISO Aspirin results in increased expression of IFT27 mRNA CTD PMID:11906190 NCBI chr 7:119,393,384...119,409,710
Ensembl chr 7:119,393,384...119,409,710
JBrowse link
G Igf2 insulin-like growth factor 2 decreases expression ISO Aspirin results in decreased expression of IGF2 mRNA CTD PMID:9399670 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Igf2r insulin-like growth factor 2 receptor increases expression ISO Aspirin results in increased expression of IGF2R mRNA CTD PMID:15928584 NCBI chr 1:48,176,095...48,264,482
Ensembl chr 1:48,176,106...48,264,477
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta decreases activity
decreases phosphorylation
decreases expression
ISO
EXP
Aspirin results in decreased activity of IKBKB protein
Aspirin results in decreased phosphorylation of IKBKB protein
Aspirin results in decreased expression of IKBKB protein
CTD PMID:16199534, PMID:16310244, PMID:16880202 NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
JBrowse link
G Il10 interleukin 10 increases response to substance
multiple interactions
increases expression
affects response to substance
ISO
EXP
IL10 polymorphism results in increased susceptibility to Aspirin
fucoidan promotes the reaction [Aspirin results in increased expression of IL10 protein]
IL10 polymorphism affects the susceptibility to Aspirin
CTD PMID:16030091, PMID:19222424, PMID:19788892 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12a interleukin 12A multiple interactions ISO Aspirin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased secretion of [IL12A protein binds to IL12B protein]] CTD PMID:15379866 NCBI chr 2:165,076,945...165,083,996
Ensembl chr 2:165,076,607...165,084,318
JBrowse link
G Il12b interleukin 12B multiple interactions ISO Aspirin inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased secretion of [IL12A protein binds to IL12B protein]] CTD PMID:15379866 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il13 interleukin 13 affects response to substance ISO IL13 polymorphism affects the susceptibility to Aspirin CTD PMID:22123380 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il17a interleukin 17A affects response to substance ISO IL17A polymorphism affects the susceptibility to Aspirin CTD PMID:22123380 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il18 interleukin 18 multiple interactions
affects response to substance
ISO Aspirin inhibits the reaction [Acetaminophen results in increased expression of IL18 mRNA]
IL18 polymorphism affects the susceptibility to Aspirin
CTD PMID:19164858, PMID:21692767 NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [Aspirin co-treated with IL1A] results in increased expression of TNF mRNA; Aspirin promotes the reaction [IL1A results in increased expression of CXCL1 mRNA]; Aspirin promotes the reaction [IL1A results in increased expression of IL1B mRNA]; Aspirin promotes the reaction [IL1A results in increased expression of IL6 mRNA]; Aspirin promotes the reaction [IL1A results in increased expression of PTGS2 mRNA]; Aspirin promotes the reaction [IL1A results in increased expression of PTGS2 protein]; Aspirin promotes the reaction [IL1A results in increased phosphorylation of MAPK14 protein]; IL1A promotes the reaction [Aspirin results in increased expression of PTGS2 mRNA]; IL1A promotes the reaction [Aspirin results in increased expression of PTGS2 protein]; IL1A promotes the reaction [Aspirin results in increased phosphorylation of MAPK14 protein] CTD PMID:14742690 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
decreases expression
affects response to substance
ISO
EXP
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid promotes the reaction [Aspirin inhibits the reaction [IL1B results in increased chemical synthesis of Dinoprostone]]; Ascorbic Acid promotes the reaction [Aspirin inhibits the reaction [IL1B results in increased chemical synthesis of 8-epi-prostaglandin F2alpha]]; Ascorbic Acid promotes the reaction [Aspirin inhibits the reaction [IL1B results in increased chemical synthesis of Dinoprostone]]; Aspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased abundance of Dinoprostone]; Aspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of ICAM1 protein]; Aspirin inhibits the reaction [IL1B results in increased activity of EDNRB]; Aspirin inhibits the reaction [IL1B results in increased chemical synthesis of 8-epi-prostaglandin F2alpha]; Aspirin inhibits the reaction [IL1B results in increased chemical synthesis of Dinoprostone]; Aspirin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; Aspirin promotes the reaction [IL1A results in increased expression of IL1B mRNA]; Celecoxib inhibits the reaction [Aspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased expression of ICAM1 protein]]; Celecoxib promotes the reaction [Aspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased abundance of Dinoprostone]]; Naproxen promotes the reaction [Aspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased abundance of Dinoprostone]]; rofecoxib promotes the reaction [Aspirin inhibits the reaction [[lipopolysaccharide, Escherichia coli O111 B4 co-treated with IL1B protein] results in increased abundance of Dinoprostone]]
Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]]; Aspirin inhibits the reaction [[Lipopolysaccharides co-treated with TNF protein co-treated with IL1B protein] results in increased activity of NFKB1 protein]; Aspirin inhibits the reaction [[Lipopolysaccharides co-treated with TNF protein co-treated with IL1B protein] results in increased activity of RELA protein]; Aspirin inhibits the reaction [Azoxymethane results in increased expression of IL1B mRNA]; Aspirin promotes the reaction [Acetic Acid results in increased expression of IL1B protein]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B mRNA]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL1B protein]; lipopolysaccharide, Helicobacter pylori inhibits the reaction [Aspirin results in increased expression of IL1B protein]
Aspirin results in decreased expression of IL1B mRNA
IL1B polymorphism affects the susceptibility to Aspirin
Aspirin inhibits the reaction [Acetaminophen results in increased expression of IL1B mRNA]; Aspirin inhibits the reaction [Acetaminophen results in increased expression of IL1B protein]
Aspirin results in increased expression of IL1B mRNA
CTD PMID:11376495, PMID:11826407, PMID:12126971, PMID:14742690, PMID:14762100, PMID:14976132, PMID:15024038, PMID:16529823, PMID:19164858, PMID:20043115, PMID:21353610, PMID:21893697, PMID:22039321, PMID:22132000 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il1r2 interleukin 1 receptor type 2 affects response to substance ISO IL1R2 affects the susceptibility to Aspirin CTD PMID:19489917 NCBI chr 9:46,840,646...46,881,241
Ensembl chr 9:46,840,992...46,881,264
JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions ISO Aspirin inhibits the reaction [Salmonella Vaccines results in increased expression of IL1RN protein] CTD PMID:12045164 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Il2 interleukin 2 multiple interactions ISO Aspirin inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein] CTD PMID:15379866 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il2rb interleukin 2 receptor subunit beta increases expression ISO Aspirin results in increased expression of IL2RB mRNA CTD PMID:15928584 NCBI chr 7:119,701,338...119,716,238
Ensembl chr 7:119,701,251...119,716,238
JBrowse link
G Il2rg interleukin 2 receptor subunit gamma decreases expression ISO Aspirin results in decreased expression of IL2RG mRNA CTD PMID:15928584 NCBI chr  X:71,165,378...71,169,078
Ensembl chr  X:71,162,585...71,169,865
JBrowse link
G Il4 interleukin 4 multiple interactions
decreases secretion
decreases expression
increases expression
ISO Aspirin inhibits the reaction [IL4 results in increased activity of STAT6 protein]; Aspirin inhibits the reaction [IL4 results in increased expression of CYSLTR1 mRNA]; Aspirin inhibits the reaction [IL4 results in increased expression of FCER1A mRNA]; Aspirin inhibits the reaction [IL4 results in increased phosphorylation of STAT6 protein]; Aspirin promotes the reaction [CEBPB protein binds to IL4 promoter polymorphism]
Aspirin results in decreased secretion of IL4 protein
Aspirin results in decreased expression of IL4 mRNA
Aspirin results in increased expression of IL4 mRNA
CTD PMID:11238116, PMID:19767084, PMID:20921925 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression
decreases expression
ISO
EXP
Aspirin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Aspirin promotes the reaction [IL1A results in increased expression of IL6 mRNA]; Aspirin results in decreased expression of and results in decreased secretion of IL6 protein; IL6 protein inhibits the reaction [Aspirin results in decreased expression of STAT3 protein modified form]
Aspirin results in increased expression of IL6 protein
fucoidan inhibits the reaction [Aspirin results in increased expression of IL6 protein]
Aspirin results in decreased expression of IL6 protein
Aspirin results in decreased expression of IL6 mRNA
CTD PMID:14742690, PMID:15379866, PMID:16413386, PMID:19595669, PMID:19788892, PMID:19896470, PMID:20886344 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Il6st interleukin 6 signal transducer decreases expression ISO Aspirin results in decreased expression of IL6ST mRNA CTD PMID:19595669 NCBI chr 2:44,279,199...44,319,427
Ensembl chr 2:44,289,393...44,314,944
JBrowse link
G Il7r interleukin 7 receptor increases expression ISO Aspirin results in increased expression of IL7R mRNA CTD PMID:15928584
G Ilk integrin-linked kinase decreases activity
decreases expression
ISO Aspirin results in decreased activity of ILK protein
Aspirin results in decreased expression of ILK mRNA
CTD PMID:11593435, PMID:15928584 NCBI chr 1:170,578,941...170,585,192
Ensembl chr 1:170,578,889...170,585,189
JBrowse link
G Insig1 insulin induced gene 1 increases expression ISO
EXP
Aspirin results in increased expression of INSIG1 mRNA CTD PMID:12800193, PMID:15928584 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Iqgap2 IQ motif containing GTPase activating protein 2 increases expression ISO Aspirin results in increased expression of IQGAP2 mRNA CTD PMID:15456535 NCBI chr 2:26,161,628...26,439,067
Ensembl chr 2:26,167,199...26,438,790
JBrowse link
G Irf1 interferon regulatory factor 1 increases expression ISO Aspirin results in increased expression of IRF1 mRNA CTD PMID:15928584 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Irf9 interferon regulatory factor 9 decreases expression ISO Aspirin results in decreased expression of IRF9 mRNA CTD PMID:15928584 NCBI chr15:34,282,936...34,288,981
Ensembl chr15:34,282,936...34,288,138
JBrowse link
G Irs1 insulin receptor substrate 1 affects response to substance ISO IRS1 polymorphism affects the susceptibility to Aspirin CTD PMID:15066917 NCBI chr 9:88,033,668...88,086,488
Ensembl chr 9:88,033,668...88,086,488
JBrowse link
G Itga2 integrin subunit alpha 2 decreases response to substance
multiple interactions
ISO ITGA2 polymorphism results in decreased susceptibility to Aspirin
ITGA2 gene SNP affects the susceptibility to [Aspirin co-treated with clopidogrel co-treated with Adenosine Diphosphate]; ITGA2 gene SNP affects the susceptibility to [Aspirin co-treated with clopidogrel co-treated with Epinephrine]; ITGA2 gene SNP affects the susceptibility to [Aspirin co-treated with clopidogrel]
CTD PMID:15205592, PMID:16214444, PMID:18231737 NCBI chr 2:46,996,904...47,097,011
Ensembl chr 2:47,000,323...47,096,961
JBrowse link
G Itga2b integrin subunit alpha 2b decreases expression
multiple interactions
ISO Aspirin results in decreased expression of ITGA2B protein
Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of ITGA2B protein]; Aspirin results in decreased expression of [ITGA2B protein binds to ITGB2 protein]; Aspirin results in decreased expression of [ITGA2B protein binds to ITGB3 protein]; Glucose inhibits the reaction [Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of ITGA2B protein]]
CTD PMID:15140583, PMID:15381054, PMID:18413191 NCBI chr10:90,397,960...90,416,550
Ensembl chr10:90,398,132...90,415,070
JBrowse link
G Itga5 integrin subunit alpha 5 decreases expression ISO Aspirin results in decreased expression of ITGA5 mRNA CTD PMID:15928584 NCBI chr 7:144,970,444...144,993,652
Ensembl chr 7:144,970,444...144,993,652
JBrowse link
G Itgb2 integrin subunit beta 2 multiple interactions ISO Aspirin results in decreased expression of [ITGA2B protein binds to ITGB2 protein] CTD PMID:15140583 NCBI chr20:11,777,773...11,815,647
Ensembl chr20:11,777,783...11,815,647
JBrowse link
G Itgb3 integrin subunit beta 3 multiple interactions
increases expression
decreases response to substance
affects response to substance
ISO Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of ITGB3 protein]; Aspirin results in decreased expression of [ITGA2B protein binds to ITGB3 protein]; Glucose inhibits the reaction [Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of ITGB3 protein]]; ITGB3 polymorphism affects the reaction [Aspirin affects the cleavage of F2 protein]
Aspirin results in increased expression of ITGB3 mRNA; Aspirin results in increased expression of ITGB3 protein
ITGB3 gene polymorphism results in decreased susceptibility to Aspirin; ITGB3 polymorphism results in decreased susceptibility to Aspirin; ITGB3 results in decreased susceptibility to Aspirin
ITGB3 gene polymorphism affects the susceptibility to Aspirin
CTD PMID:13678940, PMID:15381054, PMID:15840736, PMID:16153930, PMID:16675000, PMID:17184645, PMID:18413191, PMID:21035850 NCBI chr10:92,667,869...92,783,413
Ensembl chr10:92,667,869...92,783,410
JBrowse link
G Itgb4 integrin subunit beta 4 decreases expression ISO Aspirin results in decreased expression of ITGB4 mRNA CTD PMID:14976132 NCBI chr10:104,524,000...104,560,180
Ensembl chr10:104,523,996...104,561,078
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO Aspirin inhibits the reaction [Glucose results in increased expression of JUN protein]; Aspirin promotes the reaction [JUN protein binds to PLAUR promoter]
Aspirin results in increased expression of JUN mRNA
CTD PMID:14976132, PMID:16600694, PMID:16893520, PMID:20457246 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression EXP Aspirin results in increased expression of JUNB mRNA CTD PMID:12800193 NCBI chr19:26,092,972...26,094,756
Ensembl chr19:26,092,974...26,094,756
JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit decreases expression ISO Aspirin results in decreased expression of JUND mRNA CTD PMID:14976132 NCBI chr16:20,485,028...20,486,707
Ensembl chr16:20,485,029...20,486,707
JBrowse link
G Kat7 lysine acetyltransferase 7 decreases expression ISO Aspirin results in decreased expression of KAT7 mRNA CTD PMID:15928584 NCBI chr10:83,095,067...83,128,342
Ensembl chr10:83,095,068...83,128,297
JBrowse link
G Kcnmb4 potassium calcium-activated channel subfamily M regulatory beta subunit 4 decreases expression ISO Aspirin results in decreased expression of KCNMB4 mRNA CTD PMID:11906190 NCBI chr 7:59,461,808...59,514,759
Ensembl chr 7:59,461,799...59,514,939
JBrowse link
G Kctd13 potassium channel tetramerization domain containing 13 increases expression EXP Aspirin results in increased expression of KCTD13 mRNA CTD PMID:12800193 NCBI chr 1:198,360,627...198,378,935
Ensembl chr 1:198,360,627...198,378,934
JBrowse link
G Kdm5b lysine demethylase 5B decreases expression ISO Aspirin results in decreased expression of KDM5B mRNA CTD PMID:15928584 NCBI chr13:51,384,371...51,455,392
Ensembl chr13:51,384,389...51,455,357
JBrowse link
G Kif20b kinesin family member 20B decreases expression ISO Aspirin results in decreased expression of KIF20B mRNA CTD PMID:11906190 NCBI chr 1:253,220,038...253,275,523
Ensembl chr 1:253,221,812...253,275,490
JBrowse link
G Kif21a kinesin family member 21A increases expression ISO Aspirin results in increased expression of KIF21A mRNA CTD PMID:11906190 NCBI chr 7:132,069,962...132,200,947
Ensembl chr 7:132,071,116...132,143,470
JBrowse link
G Kif3a kinesin family member 3a increases expression
affects response to substance
ISO Aspirin results in increased expression of KIF3A mRNA
KIF3A polymorphism affects the susceptibility to Aspirin
CTD PMID:20922562 NCBI chr10:38,918,705...38,953,958
Ensembl chr10:38,918,748...38,952,785
JBrowse link
G Klrb1a killer cell lectin-like receptor subfamily B, member 1A increases expression ISO Aspirin results in increased expression of KLRB1 mRNA CTD PMID:15928584 NCBI chr 4:161,950,270...161,966,582
Ensembl chr 4:161,949,817...162,025,187
JBrowse link
G Kng2 kininogen 2 decreases activity EXP Aspirin results in decreased activity of KNG1 CTD PMID:1334751 NCBI chr11:81,509,185...81,516,759 JBrowse link
G Kpna3 karyopherin subunit alpha 3 increases expression ISO Aspirin results in increased expression of KPNA3 mRNA CTD PMID:15928584 NCBI chr15:41,696,356...41,770,112
Ensembl chr15:41,698,281...41,770,112
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase decreases expression ISO Aspirin results in decreased expression of LCK mRNA CTD PMID:15928584 NCBI chr 5:147,750,976...147,779,627
Ensembl chr 5:147,750,973...147,761,983
JBrowse link
G Lcn2 lipocalin 2 multiple interactions EXP Aspirin inhibits the reaction [Azoxymethane results in decreased expression of LCN2 mRNA] CTD PMID:20043115 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Lct lactase multiple interactions
increases activity
decreases activity
EXP [Aspirin results in decreased activity of LCT protein] which results in decreased transport of Glucose
Aspirin results in increased activity of LCT; Aspirin results in increased activity of LCT protein
CTD PMID:16382204, PMID:16855794, PMID:17147060, PMID:18604318 NCBI chr13:44,998,414...45,040,593
Ensembl chr13:44,998,414...45,040,593
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions ISO Aspirin inhibits the reaction [LDLR gene mutant form results in decreased susceptibility to Arachidonic Acid]
Aspirin inhibits the reaction [LDLR gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]]; Aspirin promotes the reaction [[Cholesterol, LDL binds to LDLR protein] which results in increased degradation of Cholesterol, LDL]; Aspirin promotes the reaction [Cholesterol, LDL binds to LDLR protein]
CTD PMID:10395027, PMID:20530721 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903
JBrowse link
G Lep leptin multiple interactions EXP [lipopolysaccharide, Helicobacter pylori co-treated with Aspirin] results in increased expression of LEP protein CTD PMID:15024038 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO Aspirin results in increased expression of LIF mRNA; Aspirin results in increased expression of LIF protein CTD PMID:21035850 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Lmna lamin A/C multiple interactions ISO Aspirin inhibits the reaction [Deoxycholic Acid results in increased cleavage of LMNA protein] CTD PMID:17644113 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G Lmo7 LIM domain 7 increases expression ISO Aspirin results in increased expression of LMO7 mRNA CTD PMID:15456535 NCBI chr15:86,242,911...86,458,512
Ensembl chr15:86,243,148...86,457,739
JBrowse link
G Lta lymphotoxin alpha affects response to substance ISO LTA gene SNP affects the susceptibility to Aspirin CTD PMID:16931544 NCBI chr20:4,851,889...4,854,677
Ensembl chr20:4,852,496...4,854,677
JBrowse link
G Ltc4s leukotriene C4 synthase affects response to substance ISO LTC4S affects the susceptibility to Aspirin; LTC4S gene SNP affects the susceptibility to Aspirin; LTC4S polymorphism affects the susceptibility to Aspirin CTD PMID:15100686, PMID:16433794, PMID:19767084, PMID:19862937, PMID:20485159 NCBI chr10:35,736,486...35,743,088
Ensembl chr10:35,737,664...35,739,625
JBrowse link
G Ly9 lymphocyte antigen 9 increases expression ISO Aspirin results in increased expression of LY9 mRNA CTD PMID:11906190 NCBI chr13:90,002,779...90,022,346
Ensembl chr13:90,002,783...90,022,269
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase increases expression ISO Aspirin results in increased expression of LYN mRNA CTD PMID:15928584 NCBI chr 5:16,526,058...16,642,648
Ensembl chr 5:16,526,058...16,642,648
JBrowse link
G Madd MAP-kinase activating death domain decreases expression ISO Aspirin results in decreased expression of MADD mRNA CTD PMID:15928584 NCBI chr 3:79,960,301...80,003,023
Ensembl chr 3:79,960,301...80,003,032
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 increases expression ISO Aspirin results in increased expression of MAP2K1 mRNA CTD PMID:20457246 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 decreases expression ISO Aspirin results in decreased expression of MAP2K2 mRNA CTD PMID:15928584 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 decreases expression ISO Aspirin results in decreased expression of MAP2K5 mRNA CTD PMID:15928584 NCBI chr 8:68,055,976...68,282,656
Ensembl chr 8:68,055,972...68,282,590
JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 decreases expression ISO Aspirin results in decreased expression of MAP4K4 mRNA CTD PMID:15928584 NCBI chr 9:46,657,444...46,782,545
Ensembl chr 9:46,657,575...46,782,545
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases activity
decreases expression
ISO Aspirin inhibits the reaction [HGF results in increased activity of MAPK1 protein]; Aspirin results in decreased phosphorylation of and results in decreased activity of MAPK1 protein
Aspirin results in increased activity of MAPK1 protein
Aspirin results in decreased expression of MAPK1 protein modified form
CTD PMID:10993886, PMID:11981761, PMID:15447849, PMID:20116423, PMID:21617849 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk12 mitogen-activated protein kinase 12 decreases expression ISO Aspirin results in decreased expression of MAPK12 mRNA CTD PMID:20514442 NCBI chr 7:130,109,214...130,120,918
Ensembl chr 7:130,109,663...130,120,579
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions
increases phosphorylation
ISO Aspirin promotes the reaction [IL1A results in increased phosphorylation of MAPK14 protein]; IL1A promotes the reaction [Aspirin results in increased phosphorylation of MAPK14 protein] CTD PMID:14742690 NCBI chr20:5,933,290...5,995,137
Ensembl chr20:5,933,303...5,995,137
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases expression
increases activity
ISO Aspirin inhibits the reaction [HGF results in increased activity of MAPK3 protein]; Aspirin results in decreased phosphorylation of and results in decreased activity of MAPK3 protein
Aspirin results in decreased expression of MAPK3 protein modified form
Aspirin results in increased activity of MAPK3 protein
CTD PMID:10993886, PMID:11981761, PMID:15447849, PMID:20116423, PMID:21617849 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapkapk3 MAPK activated protein kinase 3 decreases expression ISO Aspirin results in decreased expression of MAPKAPK3 mRNA CTD PMID:15928584 NCBI chr 8:116,012,126...116,046,012
Ensembl chr 8:116,012,121...116,045,954
JBrowse link
G Mcam melanoma cell adhesion molecule increases expression ISO Aspirin results in increased expression of MCAM mRNA CTD PMID:15456535 NCBI chr 8:48,472,824...48,481,005
Ensembl chr 8:48,472,824...48,481,001
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression
multiple interactions
ISO Aspirin results in decreased expression of MCL1 protein
Aspirin results in increased degradation of and results in decreased expression of MCL1 protein
CTD PMID:19936928, PMID:20116423 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression EXP Aspirin results in decreased expression of MCM5 mRNA CTD PMID:12800193 NCBI chr19:14,523,482...14,561,281
Ensembl chr19:14,523,554...14,561,278
JBrowse link
G Mcm6 minichromosome maintenance complex component 6 decreases expression EXP Aspirin results in decreased expression of MCM6 mRNA CTD PMID:12800193 NCBI chr13:45,042,882...45,068,073
Ensembl chr13:45,042,882...45,068,077
JBrowse link
G Mdm2 MDM2 proto-oncogene decreases expression ISO Aspirin results in decreased expression of MDM2 mRNA CTD PMID:20457246 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Med4 mediator complex subunit 4 increases expression ISO Aspirin results in increased expression of MED4 mRNA CTD PMID:15928584 NCBI chr15:55,406,543...55,416,816
Ensembl chr15:55,406,543...55,416,815
JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase decreases expression
multiple interactions
ISO Aspirin results in decreased expression of CMET protein
CTNNB1 affects the reaction [Aspirin results in decreased expression of CMET protein]
CTD PMID:16878161 NCBI chr 4:44,747,467...44,854,628
Ensembl chr 4:44,774,741...44,852,665
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions EXP Aspirin inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of MKI67 protein] CTD PMID:29031619 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Mlf2 myeloid leukemia factor 2 decreases expression ISO Aspirin results in decreased expression of MLF2 mRNA CTD PMID:15928584 NCBI chr 4:157,452,578...157,457,254
Ensembl chr 4:157,452,607...157,457,249
JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression
multiple interactions
EXP Aspirin results in increased expression of MMP13 mRNA
[Aspirin co-treated with Carbon Tetrachloride] results in increased expression of and results in increased cleavage of MMP13 protein
CTD PMID:12800193, PMID:21360558 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression
multiple interactions
decreases secretion
ISO
EXP
Aspirin results in decreased expression of MMP2
[Aspirin co-treated with Carbon Tetrachloride] results in increased expression of MMP2 protein
Aspirin results in decreased secretion of MMP2 protein
Aspirin results in decreased expression of MMP2 mRNA
CTD PMID:18971601, PMID:19462226, PMID:21360558 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions EXP Aspirin inhibits the reaction [Azoxymethane results in increased expression of MMP3 mRNA] CTD PMID:20043115 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression
multiple interactions
EXP Aspirin results in decreased expression of MMP7 mRNA
Aspirin inhibits the reaction [Azoxymethane results in increased expression of MMP7 mRNA]
CTD PMID:12800193, PMID:20043115 NCBI chr 8:5,893,253...5,900,965
Ensembl chr 8:5,893,249...5,901,049
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases secretion
decreases expression
decreases activity
ISO
EXP
Aspirin inhibits the reaction [HGF results in increased expression of MMP9]
Aspirin inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of MMP9 protein]
Aspirin results in decreased secretion of MMP9 protein
Aspirin results in decreased expression of MMP9 mRNA
Aspirin results in decreased expression of MMP9; Aspirin results in decreased expression of MMP9 mRNA
Aspirin results in decreased activity of MMP9 protein
CTD PMID:11981761, PMID:15928584, PMID:18971601, PMID:19462226, PMID:19880272, PMID:20137092, PMID:29031619 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mob2 MOB kinase activator 2 increases expression ISO Aspirin results in increased expression of MOB2 mRNA CTD PMID:15456535 NCBI chr 1:214,953,992...214,962,106
Ensembl chr 1:214,954,553...214,971,929
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases expression
EXP Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein]; Bee Venoms inhibits the reaction [Aspirin results in increased expression of MPO protein]; Ranitidine inhibits the reaction [Aspirin results in increased expression of MPO protein] CTD PMID:21893697, PMID:22039321, PMID:30885738 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mpzl1 myelin protein zero-like 1 increases expression EXP Aspirin results in increased expression of MPZL1 mRNA CTD PMID:12800193 NCBI chr13:83,805,244...83,842,074
Ensembl chr13:83,805,244...83,842,051
JBrowse link
G Mrpl46 mitochondrial ribosomal protein L46 increases expression ISO Aspirin results in increased expression of MRPL46 mRNA CTD PMID:15928584 NCBI chr 1:140,469,557...140,477,634
Ensembl chr 1:140,469,280...140,477,796
JBrowse link
G Ms4a2 membrane spanning 4-domains A2 affects response to substance ISO MS4A2 polymorphism affects the susceptibility to Aspirin; MS4A2 SNP affects the susceptibility to Aspirin CTD PMID:16839402, PMID:18379861, PMID:18534082 NCBI chr 1:227,957,363...227,965,312
Ensembl chr 1:227,957,302...227,965,386
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I increases expression EXP Aspirin results in increased expression of COX1 mRNA CTD PMID:8554334 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt-nd1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 increases expression EXP Aspirin results in increased expression of ND1 mRNA CTD PMID:8554334 NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
JBrowse link
G Mt1 metallothionein 1 multiple interactions
increases expression
ISO
EXP
Aspirin inhibits the reaction [Copper results in increased activity of MT1 promoter]
Aspirin results in increased expression of MT1A mRNA
CTD PMID:12800193, PMID:14576086 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mta1 metastasis associated 1 increases expression ISO Aspirin results in increased expression of MTA1 mRNA CTD PMID:15456535 NCBI chr 6:137,911,302...137,950,066
Ensembl chr 6:137,924,293...137,950,075
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO Aspirin results in decreased phosphorylation of and results in increased expression of MTOR protein CTD PMID:23363784 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Mttp microsomal triglyceride transfer protein decreases expression ISO Aspirin results in decreased expression of MTTP mRNA CTD PMID:27089845 NCBI chr 2:243,366,181...243,407,608
Ensembl chr 2:243,366,181...243,407,608
JBrowse link
G Mx2 MX dynamin like GTPase 2 decreases expression ISO Aspirin results in decreased expression of MX1 mRNA CTD PMID:15928584 NCBI chr11:38,035,306...38,066,185
Ensembl chr11:38,035,450...38,059,950
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
increases expression
multiple interactions
EXP
ISO
Aspirin results in decreased expression of MYC mRNA
Aspirin results in decreased expression of MYC mRNA; Aspirin results in decreased expression of MYC protein
Aspirin results in increased expression of MYC mRNA
CTNNB1 affects the reaction [Aspirin results in decreased expression of MYC protein]
CTD PMID:11906190, PMID:12800193, PMID:16878161, PMID:20457246, PMID:21721879 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Naa15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit decreases expression EXP Aspirin results in decreased expression of NAA15 mRNA CTD PMID:12800193 NCBI chr 2:140,471,437...140,534,259
Ensembl chr 2:140,471,690...140,534,259
JBrowse link
G Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit increases expression ISO Aspirin results in increased expression of NAA38 mRNA CTD PMID:15456535 NCBI chr10:55,997,614...55,998,691
Ensembl chr10:55,997,614...55,998,691
JBrowse link
G Nat1 N-acetyltransferase 1 decreases activity EXP Aspirin results in decreased activity of NAT1 protein CTD PMID:15796213 NCBI chr16:23,970,742...23,991,573
Ensembl chr16:23,970,743...23,991,573
JBrowse link
G Nat2 N-acetyltransferase 2 affects response to substance ISO NAT2 polymorphism affects the susceptibility to Aspirin CTD PMID:20602614 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions
decreases expression
ISO Aspirin inhibits the reaction [Hydrogen Peroxide results in increased expression of NCF1 mRNA]
Aspirin results in decreased expression of NCF1 mRNA
CTD PMID:21353610, PMID:22306536 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
G Ndst2 N-deacetylase and N-sulfotransferase 2 increases expression ISO Aspirin results in increased expression of NDST2 mRNA CTD PMID:11906190 NCBI chr15:3,995,797...4,006,491
Ensembl chr15:3,996,048...4,006,491
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
decreases expression
decreases localization
increases activity
ISO
EXP
Aspirin inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Aspirin inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]; Aspirin promotes the reaction [NFKB1 protein binds to SAT1 promoter]
Aspirin results in decreased expression of NFKB1 mRNA
Aspirin results in decreased localization of NFKB1 protein
Aspirin inhibits the reaction [[Lipopolysaccharides co-treated with TNF protein co-treated with IL1B protein] results in increased activity of NFKB1 protein]
[Pertussis Toxin co-treated with Dithiothreitol] inhibits the reaction [Aspirin inhibits the reaction [Lipopolysaccharides promotes the reaction [[RELA protein co-treated with NFKB1 protein] binds to TNF promoter]]]; Aspirin inhibits the reaction [Lipopolysaccharides promotes the reaction [[RELA protein co-treated with NFKB1 protein] binds to TNF promoter]]
Aspirin results in increased activity of NFKB1 protein
CTD PMID:9281604, PMID:11826407, PMID:14976132, PMID:15489888, PMID:16262603, PMID:17259377, PMID:20457246 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
decreases expression
decreases degradation
increases expression
increases degradation
ISO
EXP
Aspirin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Aspirin inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; Aspirin inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Aspirin inhibits the reaction [TNF results in increased degradation of NFKBIA protein]; Aspirin inhibits the reaction [TNF results in increased phosphorylation of NFKBIA protein]; Aspirin results in decreased phosphorylation of and results in increased expression of NFKBIA protein
Aspirin results in decreased expression of NFKBIA mRNA
Aspirin results in decreased degradation of NFKBIA protein
Aspirin results in increased expression of NFKBIA protein
Aspirin results in increased degradation of NFKBIA protein
CTD PMID:14753751, PMID:15036249, PMID:15188000, PMID:15489888, PMID:15770215, PMID:16199534, PMID:16310244, PMID:16880202, PMID:16936242, PMID:20457246 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions ISO Aspirin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased degradation of NFKBIB protein]; Aspirin inhibits the reaction [TNF results in increased phosphorylation of NFKBIB protein] CTD PMID:14753751, PMID:15036249 NCBI chr 1:86,941,073...86,948,845
Ensembl chr 1:86,941,074...86,948,845
JBrowse link
G Nfkbiz NFKB inhibitor zeta increases expression ISO Aspirin results in increased expression of NFKBIZ mRNA CTD PMID:15928584 NCBI chr11:47,243,342...47,271,487
Ensembl chr11:47,243,342...47,271,487
JBrowse link
G Ngfr nerve growth factor receptor increases expression ISO Aspirin analog results in increased expression of NGFR protein CTD PMID:17447067 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Ninj1 ninjurin 1 decreases expression ISO Aspirin results in decreased expression of NINJ1 mRNA CTD PMID:15928584 NCBI chr17:15,866,235...15,881,284
Ensembl chr17:15,866,237...15,881,327
JBrowse link
G Nkg7 natural killer cell granule protein 7 decreases expression ISO Aspirin results in decreased expression of NKG7 mRNA CTD PMID:15928584 NCBI chr 1:98,492,873...98,493,940
Ensembl chr 1:98,492,828...98,493,978
JBrowse link
G Nkx2-1 NK2 homeobox 1 affects expression EXP Aspirin affects the expression of NKX2-1 mRNA CTD PMID:12800193 NCBI chr 6:77,418,096...77,423,383
Ensembl chr 6:77,418,096...77,421,286
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 affects response to substance ISO NLRP3 SNP affects the susceptibility to Aspirin CTD PMID:19767079 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nme6 NME/NM23 nucleoside diphosphate kinase 6 increases expression ISO Aspirin results in increased expression of NME6 mRNA CTD PMID:15456535 NCBI chr 8:117,920,912...117,928,148
Ensembl chr 8:117,920,944...117,928,195
JBrowse link
G Nolc1 nucleolar and coiled-body phosphoprotein 1 decreases expression EXP Aspirin results in decreased expression of NOLC1 mRNA CTD PMID:12800193 NCBI chr 1:265,829,055...265,839,819
Ensembl chr 1:265,829,108...265,839,818
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression
increases expression
ISO
EXP
Ascorbic Acid inhibits the reaction [Aspirin results in increased expression of NOS2 protein]
[Aspirin results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide
Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of NOS2 mRNA]
CTD PMID:10860828, PMID:16310244, PMID:17218764, PMID:21893697 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions ISO Aspirin inhibits the reaction [Everolimus results in decreased expression of NOS3 protein]; Aspirin inhibits the reaction [Paclitaxel results in decreased expression of NOS3 protein]; Aspirin inhibits the reaction [Sirolimus results in decreased expression of NOS3 protein]; Aspirin promotes the reaction [NOS3 protein binds to CALM1 protein]; Aspirin results in increased acetylation of and results in increased activity of NOS3 protein; HDAC3 inhibits the reaction [Aspirin results in increased acetylation of and results in increased activity of NOS3 protein]; HDAC3 protein inhibits the reaction [Aspirin promotes the reaction [NOS3 protein binds to CALM1 protein]] CTD PMID:19520256, PMID:20705923 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Npepps aminopeptidase puromycin sensitive decreases expression ISO Aspirin results in decreased expression of NPEPPS mRNA CTD PMID:11906190 NCBI chr10:85,140,368...85,222,861
Ensembl chr10:85,140,370...85,222,861
JBrowse link
G Nppb natriuretic peptide B affects expression
multiple interactions
increases expression
EXP
ISO
Aspirin affects the expression of NPPB mRNA
[carvedilol co-treated with temocapril hydrochloride co-treated with Spironolactone co-treated with Aspirin] affects the expression of NPPB protein
Aspirin results in increased expression of NPPB mRNA
CTD PMID:12800193, PMID:21378469 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Npr1 natriuretic peptide receptor 1 decreases expression ISO Aspirin results in decreased expression of NPR1 mRNA CTD PMID:11906190 NCBI chr 2:189,840,403...189,857,032
Ensembl chr 2:189,840,403...189,856,090
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases activity
ISO Acetylcysteine inhibits the reaction [Aspirin analog results in increased activity of NQO1 protein] CTD PMID:23035985 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression ISO Aspirin results in increased expression of NR4A3 mRNA CTD PMID:15928584 NCBI chr 5:63,781,801...63,822,890
Ensembl chr 5:63,781,801...63,821,637
JBrowse link
G Nrcam neuronal cell adhesion molecule decreases expression ISO Aspirin results in decreased expression of NRCAM mRNA CTD PMID:15456535 NCBI chr 6:64,297,843...64,867,408
Ensembl chr 6:64,297,888...64,864,996
JBrowse link
G Nubp2 nucleotide binding protein 2 decreases expression ISO Aspirin results in decreased expression of NUBP2 mRNA CTD PMID:15456535, PMID:15928584 NCBI chr10:14,244,201...14,247,930
Ensembl chr10:14,244,203...14,247,886
JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A increases expression ISO Aspirin results in increased expression of OAS1 mRNA CTD PMID:14976132 NCBI chr12:41,200,680...41,211,393
Ensembl chr12:41,200,718...41,211,909
JBrowse link
G Odc1 ornithine decarboxylase 1 increases expression
increases response to substance
ISO Aspirin results in increased expression of ODC1 mRNA
ODC1 polymorphism results in increased susceptibility to Aspirin
CTD PMID:14976132, PMID:18413818 NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
JBrowse link
G Orc4 origin recognition complex, subunit 4 increases expression ISO Aspirin results in increased expression of ORC4 mRNA CTD PMID:11906190 NCBI chr 3:33,034,913...33,075,833
Ensembl chr 3:33,037,034...33,075,685
JBrowse link
G Osm oncostatin M multiple interactions ISO Aspirin inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY analog results in increased secretion of OSM protein] CTD PMID:17303692 NCBI chr14:84,457,487...84,469,426
Ensembl chr14:84,465,515...84,470,409
JBrowse link
G Osr1 odd-skipped related transcription factor 1 increases expression ISO Aspirin results in increased expression of OSR1 mRNA CTD PMID:15928584 NCBI chr 6:35,314,431...35,321,458
Ensembl chr 6:35,314,444...35,321,667
JBrowse link
G Otc ornithine carbamoyltransferase decreases expression ISO Aspirin results in decreased expression of OTC protein CTD PMID:8295421 NCBI chr  X:13,524,804...13,601,074
Ensembl chr  X:13,524,607...13,601,069
JBrowse link
G P2ry1 purinergic receptor P2Y1 decreases response to substance
affects response to substance
ISO P2RY1 polymorphism results in decreased susceptibility to Aspirin; P2RY1 SNP results in decreased susceptibility to Aspirin
P2RY1 affects the susceptibility to Aspirin
CTD PMID:15757620, PMID:17559347, PMID:21429568 NCBI chr 2:151,314,818...151,320,312
Ensembl chr 2:151,314,818...151,320,319
JBrowse link
G P2ry12 purinergic receptor P2Y12 affects response to substance ISO P2RY12 affects the susceptibility to Aspirin CTD PMID:14597584 NCBI chr 2:149,440,807...149,482,592
Ensembl chr 2:149,441,598...149,444,548
JBrowse link
G Pag1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 increases expression ISO Aspirin results in increased expression of PAG1 mRNA CTD PMID:15928584 NCBI chr 2:94,266,104...94,277,680
Ensembl chr 2:94,266,213...94,277,676
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO [Aspirin co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein; Aspirin inhibits the reaction [Deoxycholic Acid results in increased cleavage of PARP1 protein]; Aspirin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]; Aspirin promotes the reaction [troglitazone results in increased cleavage of PARP1 protein]; Aspirin results in increased cleavage of and results in increased activity of PARP1 protein; BCL2 protein inhibits the reaction [Aspirin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]; troglitazone promotes the reaction [Aspirin results in increased cleavage of PARP1 protein] CTD PMID:9694730, PMID:11228543, PMID:11532860, PMID:15481331, PMID:16199534, PMID:17644113, PMID:18483385, PMID:19595669, PMID:19908241 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pcbp1 poly(rC) binding protein 1 decreases expression ISO Aspirin results in decreased expression of PCBP1 mRNA CTD PMID:15928584 NCBI chr 4:118,327,185...118,329,223
Ensembl chr 4:118,327,533...118,328,602
JBrowse link
G Pcdh17 protocadherin 17 increases expression ISO Aspirin results in increased expression of PCDH17 mRNA CTD PMID:11906190 NCBI chr15:67,555,835...67,647,990
Ensembl chr15:67,555,835...67,645,088
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression EXP Aspirin results in increased expression of PCNA protein CTD PMID:14563943 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Pcnp PEST proteolytic signal containing nuclear protein increases expression ISO Aspirin results in increased expression of PCNP mRNA CTD PMID:15928584 NCBI chr11:47,055,641...47,070,319
Ensembl chr11:47,061,354...47,068,648
JBrowse link
G Pcsk1 proprotein convertase subtilisin/kexin type 1 decreases expression ISO Aspirin results in decreased expression of PCSK1 mRNA CTD PMID:11906190 NCBI chr 2:91,450,162...91,497,091
Ensembl chr 2:91,450,162...91,497,091
JBrowse link
G Pcsk7 proprotein convertase subtilisin/kexin type 7 decreases expression ISO Aspirin results in decreased expression of PCSK7 mRNA CTD PMID:15928584 NCBI chr 8:50,200,069...50,222,655
Ensembl chr 8:50,200,069...50,222,630
JBrowse link
G Pdcd10 programmed cell death 10 increases expression ISO Aspirin results in increased expression of PDCD10 mRNA CTD PMID:15928584 NCBI chr 2:173,966,701...174,012,730
Ensembl chr 2:173,967,080...174,012,676
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions ISO Aspirin promotes the reaction [Adenosine Diphosphate results in increased secretion of PDGFB protein] CTD PMID:17303692 NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
JBrowse link
G Pdlim7 PDZ and LIM domain 7 decreases expression ISO Aspirin results in decreased expression of PDLIM7 mRNA CTD PMID:15928584 NCBI chr17:9,653,510...9,668,715
Ensembl chr17:9,653,561...9,668,712
JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 decreases expression ISO Aspirin results in decreased expression of PECAM1 mRNA; Aspirin results in decreased expression of PECAM1 protein CTD PMID:15381054, PMID:15456535 NCBI chr10:94,850,971...94,913,202 JBrowse link
G Pef1 penta-EF hand domain containing 1 decreases expression ISO Aspirin results in decreased expression of PEF1 mRNA CTD PMID:15928584 NCBI chr 5:148,320,610...148,343,876
Ensembl chr 5:148,320,438...148,343,886
JBrowse link
G Pepd peptidase D increases activity ISO Aspirin results in increased activity of PEPD protein CTD PMID:16991207 NCBI chr 1:90,820,670...91,285,128 JBrowse link
G Pf4 platelet factor 4 multiple interactions ISO Aspirin inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY analog results in increased secretion of PF4 protein] CTD PMID:17303692 NCBI chr14:18,848,549...18,849,258
Ensembl chr14:18,848,549...18,849,258
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 decreases expression ISO Aspirin results in decreased expression of PFKFB3 mRNA CTD PMID:11906190 NCBI chr17:70,632,778...70,713,736
Ensembl chr17:70,684,134...70,713,726
JBrowse link
G Pfn1 profilin 1 decreases expression ISO Aspirin results in decreased expression of PFN1 mRNA CTD PMID:15928584 NCBI chr10:57,273,003...57,275,708
Ensembl chr10:57,273,005...57,275,708
JBrowse link
G Phb prohibitin decreases expression ISO Aspirin results in decreased expression of PHB mRNA CTD PMID:14976132 NCBI chr10:83,476,107...83,488,878
Ensembl chr10:83,476,107...83,488,878
JBrowse link
G Phb2 prohibitin 2 decreases expression ISO Aspirin results in decreased expression of PHB2 mRNA CTD PMID:15928584 NCBI chr 4:157,230,769...157,235,375
Ensembl chr 4:157,230,769...157,235,367
JBrowse link
G Pi4kb phosphatidylinositol 4-kinase beta decreases expression ISO Aspirin results in decreased expression of PI4KB mRNA CTD PMID:15928584 NCBI chr 2:196,139,724...196,172,055
Ensembl chr 2:196,139,755...196,171,713
JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein decreases expression ISO Aspirin results in decreased expression of PICALM mRNA CTD PMID:11906190 NCBI chr 1:154,377,229...154,458,966
Ensembl chr 1:154,377,247...154,458,425
JBrowse link
G Pik3c2a phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha decreases expression ISO Aspirin results in decreased expression of PIK3C2A mRNA CTD PMID:11906190 NCBI chr 1:185,210,922...185,326,314
Ensembl chr 1:185,210,922...185,326,314
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression ISO Aspirin results in decreased expression of PIK3R1 mRNA CTD PMID:20457246 NCBI chr 2:31,742,326...31,826,882
Ensembl chr 2:31,745,088...31,826,867
JBrowse link
G Pitx1 paired-like homeodomain 1 increases expression ISO Aspirin results in increased expression of PITX1 mRNA CTD PMID:11906190 NCBI chr17:8,873,184...8,884,428
Ensembl chr17:8,878,270...8,884,423
JBrowse link
G Pla2g4a phospholipase A2 group IVA decreases expression ISO Aspirin results in decreased expression of PLA2G4A mRNA CTD PMID:10706128 NCBI chr13:67,062,252...67,206,688
Ensembl chr13:66,988,937...67,206,693
JBrowse link
G Pla2g6 phospholipase A2 group VI increases expression ISO Aspirin results in increased expression of PLA2G6 mRNA CTD PMID:11906190 NCBI chr 7:120,519,479...120,559,716
Ensembl chr 7:120,519,467...120,559,347
JBrowse link
G Plaur plasminogen activator, urokinase receptor multiple interactions
affects expression
increases expression
ISO
EXP
Aspirin promotes the reaction [FOSL1 protein binds to PLAUR promoter]; Aspirin promotes the reaction [H4-16 protein modified form binds to PLAUR promoter]; Aspirin promotes the reaction [JUN protein binds to PLAUR promoter]
Aspirin affects the expression of PLAUR mRNA
Aspirin results in increased expression of PLAUR mRNA; Aspirin results in increased expression of PLAUR protein
CTD PMID:12800193, PMID:16893520 NCBI chr 1:81,328,171...81,344,954
Ensembl chr 1:81,328,183...81,344,708
JBrowse link
G Plcd4 phospholipase C, delta 4 increases expression EXP Aspirin results in increased expression of PLCD4 mRNA CTD PMID:12800193 NCBI chr 9:81,816,395...81,844,364
Ensembl chr 9:81,816,872...81,844,364
JBrowse link
G Plin2 perilipin 2 increases expression EXP Aspirin results in increased expression of PLIN2 mRNA CTD PMID:12800193 NCBI chr 5:104,984,413...105,010,863
Ensembl chr 5:104,984,414...105,010,857
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression
increases response to substance
ISO Aspirin results in increased expression of PMAIP1 mRNA; Aspirin results in increased expression of PMAIP1 protein
PMAIP1 results in increased susceptibility to Aspirin
CTD PMID:15928584, PMID:19936928 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Polr2a RNA polymerase II subunit A increases expression ISO Aspirin results in increased expression of POLR2A mRNA CTD PMID:11906190 NCBI chr10:56,339,277...56,364,888
Ensembl chr10:56,339,284...56,365,084
JBrowse link
G Pon1 paraoxonase 1 increases expression
increases activity
multiple interactions
ISO
EXP
Aspirin results in increased expression of PON1 mRNA
Aspirin results in increased activity of PON1 mRNA; Aspirin results in increased activity of PON1 protein
AHR mutant form inhibits the reaction [Aspirin results in increased activity of PON1 protein]; AHR mutant form inhibits the reaction [Aspirin results in increased expression of PON1 mRNA]
CTD PMID:18519978 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Por cytochrome p450 oxidoreductase decreases expression ISO Aspirin results in decreased expression of POR mRNA CTD PMID:15928584 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects activity
multiple interactions
increases expression
decreases expression
decreases activity
ISO Aspirin affects the activity of PPARA protein
PPARA affects the reaction [Aspirin affects the expression of ABCA1 mRNA]; PPARA affects the reaction [Aspirin affects the expression of ABCA1 protein]; PPARA affects the reaction [Aspirin promotes the reaction [APOA1 affects the transport of Cholesterol]]
Aspirin results in increased expression of PPARA mRNA
Aspirin results in increased expression of PPARA; Aspirin results in increased expression of PPARA mRNA; Aspirin results in increased expression of PPARA protein
Aspirin results in decreased expression of PPARA protein
Aspirin results in decreased activity of PPARA protein
CTD PMID:15646027, PMID:16816107, PMID:18971601, PMID:19462226, PMID:19880272, PMID:21088444 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta decreases activity
increases expression
decreases expression
ISO
EXP
Aspirin results in decreased activity of PPARD protein
Aspirin results in increased expression of PPARD mRNA
Aspirin results in decreased expression of PPARD protein
CTD PMID:12800193, PMID:15646027, PMID:18678619 NCBI chr20:7,818,289...7,883,482
Ensembl chr20:7,818,289...7,885,333
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases activity
decreases expression
increases expression
multiple interactions
ISO
EXP
Aspirin results in decreased activity of PPARG protein
Aspirin results in decreased expression of PPARG mRNA
Aspirin results in increased expression of PPARG mRNA
Aspirin results in increased expression of PPARG; Aspirin results in increased expression of PPARG mRNA; Aspirin results in increased expression of PPARG protein
Aspirin inhibits the reaction [Niacin results in increased activity of PPARG protein]
CTD PMID:15646027, PMID:16386710, PMID:18222077, PMID:18971601, PMID:19462226, PMID:19880272 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppbp pro-platelet basic protein multiple interactions ISO Aspirin inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY analog results in increased secretion of PPBP protein] CTD PMID:17303692 NCBI chr14:18,852,433...18,853,237
Ensembl chr14:18,851,954...18,853,315
JBrowse link
G Ppib peptidylprolyl isomerase B decreases expression ISO Aspirin results in decreased expression of PPIB mRNA CTD PMID:15928584 NCBI chr 8:71,719,681...71,725,538
Ensembl chr 8:71,719,563...71,725,562
JBrowse link
G Ppig peptidylprolyl isomerase G increases expression ISO Aspirin results in increased expression of PPIG mRNA CTD PMID:15928584 NCBI chr 3:55,959,756...55,990,040
Ensembl chr 3:55,960,067...55,988,968
JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A decreases expression ISO Aspirin results in decreased expression of PPP1R12A mRNA CTD PMID:11906190 NCBI chr 7:51,404,971...51,515,382
Ensembl chr 7:51,404,919...51,515,373
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression EXP Aspirin results in increased expression of PPP1R15A mRNA CTD PMID:12800193 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974
JBrowse link
G Ppp1r2 protein phosphatase 1, regulatory (inhibitor) subunit 2 decreases expression ISO Aspirin results in decreased expression of PPP1R2 mRNA CTD PMID:11906190 NCBI chr11:72,748,789...73,034,683
Ensembl chr11:73,022,063...73,034,682
JBrowse link
G Ppp4c protein phosphatase 4, catalytic subunit decreases expression ISO Aspirin results in decreased expression of PPP4C mRNA CTD PMID:15928584 NCBI chr 1:198,219,012...198,225,775
Ensembl chr 1:198,219,054...198,225,580
JBrowse link
G Prep prolyl endopeptidase decreases expression ISO Aspirin results in decreased expression of PREP mRNA CTD PMID:15928584 NCBI chr20:50,172,618...50,269,992
Ensembl chr20:50,172,618...50,269,992
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases expression
multiple interactions
ISO Aspirin results in increased expression of PRKAA1 protein modified form
CES1 protein promotes the reaction [Aspirin results in increased expression of PRKAA1 protein modified form]
CTD PMID:25743752 NCBI chr 2:54,857,688...54,893,404
Ensembl chr 2:54,857,688...54,893,404
JBrowse link
G Prkcb protein kinase C, beta multiple interactions
affects expression
ISO Aspirin inhibits the reaction [Deoxycholic Acid results in increased expression of PRKCB protein]
Aspirin affects the expression of PRKCB protein
CTD PMID:17644113 NCBI chr 1:192,233,569...192,575,339
Ensembl chr 1:192,233,910...192,574,831
JBrowse link
G Prkcd protein kinase C, delta increases cleavage ISO Aspirin results in increased cleavage of PRKCD protein CTD PMID:11228543 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions ISO Aspirin inhibits the reaction [Deoxycholic Acid results in increased cleavage of PRKCE protein] CTD PMID:17644113 NCBI chr 6:9,483,400...9,973,396
Ensembl chr 6:9,790,422...9,973,396
JBrowse link
G Prnp prion protein increases expression EXP Aspirin results in increased expression of PRNP mRNA CTD PMID:12800193 NCBI chr 3:124,515,917...124,531,320
Ensembl chr 3:124,515,978...124,531,316
JBrowse link
G Prp15 proline-rich protein 15 decreases expression ISO Aspirin results in decreased expression of PRH2 mRNA CTD PMID:11906190 NCBI chr 4:166,222,418...166,293,492
Ensembl chr 4:166,222,451...166,224,565
JBrowse link
G Psat1 phosphoserine aminotransferase 1 decreases expression EXP Aspirin results in decreased expression of PSAT1 mRNA CTD PMID:12800193 NCBI chr 1:233,124,089...233,145,941
Ensembl chr 1:233,124,092...233,145,941
JBrowse link
G Psd pleckstrin and Sec7 domain containing increases expression ISO Aspirin results in increased expression of PSD mRNA CTD PMID:11906190 NCBI chr 1:266,059,331...266,074,774
Ensembl chr 1:266,059,331...266,074,181
JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 decreases expression ISO Aspirin results in decreased expression of PSMC6 mRNA CTD PMID:11906190 NCBI chr15:19,667,453...19,688,916
Ensembl chr15:19,667,453...19,688,914
JBrowse link
G Psmd12 proteasome 26S subunit, non-ATPase 12 increases expression ISO Aspirin results in increased expression of PSMD12 mRNA CTD PMID:15928584 NCBI chr10:95,706,808...95,725,452
Ensembl chr10:95,706,685...95,725,812
JBrowse link
G Ptgdr2 prostaglandin D2 receptor 2 affects response to substance ISO PTGDR2 gene SNP affects the susceptibility to Aspirin CTD PMID:20485159 NCBI chr 1:226,976,455...226,995,641
Ensembl chr 1:226,993,250...226,994,849
JBrowse link
G Ptger2 prostaglandin E receptor 2 affects response to substance ISO PTGER2 SNP affects the susceptibility to Aspirin CTD PMID:15496426 NCBI chr15:19,336,029...19,349,759
Ensembl chr15:19,338,175...19,350,210
JBrowse link
G Ptger3 prostaglandin E receptor 3 affects response to substance ISO PTGER3 polymorphism affects the susceptibility to Aspirin CTD PMID:20587336 NCBI chr 2:263,895,093...263,979,682
Ensembl chr 2:263,895,241...263,979,698
JBrowse link
G Ptges prostaglandin E synthase decreases expression ISO Aspirin results in decreased expression of PTGES mRNA; Aspirin results in decreased expression of PTGES protein CTD PMID:19880272 NCBI chr 3:9,727,408...9,738,752
Ensembl chr 3:9,727,408...9,738,752
JBrowse link
G Ptgir prostaglandin I2 receptor affects response to substance ISO PTGIR gene SNP affects the susceptibility to Aspirin CTD PMID:20485159 NCBI chr 1:78,833,449...78,835,832
Ensembl chr 1:78,833,157...78,837,623
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions
affects expression
affects response to substance
decreases activity
decreases expression
decreases response to substance
increases acetylation
ISO
EXP
[Aspirin results in increased acetylation of PTGS1 protein] which results in decreased chemical synthesis of Thromboxane A2; Aspirin inhibits the reaction [[Arachidonic Acid results in increased activity of PTGS1 protein] which results in increased susceptibility to Methamphetamine]; Aspirin inhibits the reaction [Arachidonic Acid results in increased activity of PTGS1 protein]; Aspirin inhibits the reaction [PTGS1 protein results in increased susceptibility to Methamphetamine]; PTGS1 mutant form inhibits the reaction [Aspirin promotes the reaction [romidepsin results in increased expression of CDKN1A protein]]
Aspirin affects the expression of PTGS1 protein
PTGS1 polymorphism affects the susceptibility to Aspirin
Aspirin analog results in decreased activity of PTGS1 protein; Aspirin results in decreased activity of PTGS1 protein
Aspirin results in decreased expression of PTGS1 mRNA
Aspirin promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of PTGS1 protein]; PTGS1 results in decreased susceptibility to [Hydrochloric Acid co-treated with Aspirin]
PTGS1 gene polymorphism results in decreased susceptibility to Aspirin; PTGS1 gene SNP results in decreased susceptibility to Aspirin
CTD PMID:12242329, PMID:15236176, PMID:15843042, PMID:16141368, PMID:16150050, PMID:16484611, PMID:16493486, PMID:19036898, PMID:19390185, PMID:19493461, PMID:20404564, PMID:21163909, PMID:21513785, PMID:23533533 NCBI chr 3:15,560,685...15,582,339
Ensembl chr 3:15,560,712...15,582,344
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases activity
increases expression
decreases expression
affects response to substance
decreases degradation
ISO
EXP
Ascorbic Acid inhibits the reaction [Aspirin results in increased expression of PTGS2 mRNA]; Aspirin inhibits the reaction [[Arachidonic Acid results in increased activity of PTGS2 protein] which results in increased susceptibility to Methamphetamine]; Aspirin inhibits the reaction [Arachidonic Acid results in increased activity of PTGS2 protein]; Aspirin inhibits the reaction [PTGS2 protein results in increased susceptibility to Methamphetamine]; Aspirin inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]; Aspirin inhibits the reaction [TNF results in increased expression of PTGS2 mRNA]; Aspirin inhibits the reaction [TNF results in increased expression of PTGS2 protein]; Aspirin promotes the reaction [IL1A results in increased expression of PTGS2 mRNA]; Aspirin promotes the reaction [IL1A results in increased expression of PTGS2 protein]; IL1A promotes the reaction [Aspirin results in increased expression of PTGS2 mRNA]; IL1A promotes the reaction [Aspirin results in increased expression of PTGS2 protein]; SB 203580 inhibits the reaction [Aspirin results in decreased degradation of PTGS2 mRNA]; SB 203580 inhibits the reaction [Aspirin results in increased expression of PTGS2 mRNA]; SB 203580 inhibits the reaction [Aspirin results in increased expression of PTGS2 protein]
Aspirin results in decreased activity of PTGS2 protein; Aspirin results in decreased activity of PTGS2 protein mutant form
Aspirin results in increased expression of PTGS2; Aspirin results in increased expression of PTGS2 mRNA; Aspirin results in increased expression of PTGS2 protein
Aspirin results in decreased expression of PTGS2 protein
[Aspirin co-treated with Hydrochloric Acid] results in increased expression of PTGS2 mRNA; [telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]]; apple polyphenol extract inhibits the reaction [Aspirin results in increased expression of PTGS2 mRNA]; apple polyphenol extract inhibits the reaction [Aspirin results in increased expression of PTGS2 protein]; Aspirin inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of PTGS2 protein]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of PTGS2 mRNA]
[[Aspirin co-treated with Hydrochloric Acid] results in increased expression of PTGS2 protein] which results in increased abundance of Dinoprostone; [Aspirin co-treated with Hydrochloric Acid] results in increased expression of PTGS2 mRNA; [Aspirin co-treated with Hydrochloric Acid] results in increased expression of PTGS2 protein; Aspirin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 mRNA]; Aspirin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein]
PTGS2 gene SNP affects the susceptibility to Aspirin; PTGS2 SNP affects the susceptibility to Aspirin
Aspirin results in decreased expression of PTGS2 mRNA; Aspirin results in decreased expression of PTGS2 protein
CTD PMID:9726391, PMID:10706128, PMID:12231391, PMID:12781040, PMID:14742690, PMID:15236176, PMID:15489888, PMID:15843042, PMID:15861417, PMID:16310244, PMID:16336399, PMID:16804302, PMID:17218764, PMID:17595529, PMID:18197933, PMID:18482463, PMID:19493461, PMID:19755647, PMID:19880272, PMID:20223228, PMID:20485159, PMID:21163909, PMID:21360558, PMID:21513785, PMID:21893697, PMID:22245433 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4A1 increases expression ISO Aspirin results in increased expression of PTP4A1 mRNA CTD PMID:14976132 NCBI chr 9:37,223,363...37,254,222
Ensembl chr 9:37,223,729...37,231,291
JBrowse link
G Ptprcap protein tyrosine phosphatase, receptor type, C-associated protein decreases expression ISO Aspirin results in decreased expression of PTPRCAP mRNA CTD PMID:15928584 NCBI chr 1:219,403,970...219,406,129
Ensembl chr 1:219,403,970...219,406,128
JBrowse link
G Pum2 pumilio RNA-binding family member 2 increases expression ISO Aspirin results in increased expression of PUM2 mRNA CTD PMID:15928584 NCBI chr 6:33,786,184...33,865,693
Ensembl chr 6:33,786,197...33,865,687
JBrowse link
G Pura purine rich element binding protein A increases expression EXP Aspirin results in increased expression of PURA mRNA CTD PMID:12800193 NCBI chr18:29,104,712...29,114,918
Ensembl chr18:29,110,242...29,111,156
JBrowse link
G Pus1 pseudouridine synthase 1 increases expression ISO Aspirin results in increased expression of PUS1 mRNA CTD PMID:15456535 NCBI chr12:51,936,721...51,945,930
Ensembl chr12:51,937,175...51,945,928
JBrowse link
G Pxn paxillin decreases expression ISO Aspirin results in decreased expression of PXN mRNA CTD PMID:15928584 NCBI chr12:46,797,953...46,845,107
Ensembl chr12:46,797,954...46,845,080
JBrowse link
G Pygl glycogen phosphorylase L affects binding EXP Aspirin binds to PYGL protein CTD PMID:15236443 NCBI chr 6:92,597,759...92,643,734
Ensembl chr 6:92,597,706...92,643,847
JBrowse link
G Rab2a RAB2A, member RAS oncogene family increases expression ISO Aspirin results in increased expression of RAB2A mRNA CTD PMID:15456535 NCBI chr 5:21,632,654...21,696,721
Ensembl chr 5:21,632,926...21,695,519
JBrowse link
G Rabggta Rab geranylgeranyltransferase subunit alpha increases expression ISO Aspirin results in increased expression of RABGGTA mRNA CTD PMID:11906190 NCBI chr15:34,393,419...34,400,466
Ensembl chr15:34,393,233...34,400,449
JBrowse link
G Rac1 Rac family small GTPase 1 increases expression ISO Aspirin results in increased expression of RAC1 mRNA; Aspirin results in increased expression of RAC1 protein CTD PMID:14976132 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase decreases expression ISO Aspirin results in decreased expression of RAF1 mRNA CTD PMID:20457246 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Ralb RAS like proto-oncogene B decreases expression ISO Aspirin results in decreased expression of RALB mRNA CTD PMID:11906190 NCBI chr13:35,494,716...35,531,503
Ensembl chr13:35,494,721...35,511,020
JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions
increases expression
decreases expression
ISO Aspirin inhibits the reaction [troglitazone results in decreased expression of RB1 protein modified form]; Aspirin promotes the reaction [troglitazone results in increased expression of RB1 protein]; troglitazone inhibits the reaction [Aspirin results in decreased expression of RB1 protein modified form]; troglitazone promotes the reaction [Aspirin results in increased expression of RB1 protein] CTD PMID:19908241 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Reep6 receptor accessory protein 6 increases expression ISO Aspirin results in increased expression of REEP6 mRNA CTD PMID:11906190 NCBI chr 7:12,240,059...12,246,814
Ensembl chr 7:12,240,060...12,246,729
JBrowse link
G Reg1a regenerating family member 1 alpha decreases response to substance
increases expression
EXP REG1A results in decreased susceptibility to Aspirin
Aspirin results in increased expression of REG1A mRNA; Aspirin results in increased expression of REG1A protein
CTD PMID:14563943 NCBI chr 4:109,497,962...109,500,626
Ensembl chr 4:109,497,962...109,501,082
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases localization
increases localization
ISO
EXP
Aspirin inhibits the reaction [Glucose results in increased expression of RELA protein]; Aspirin inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein]; Aspirin inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Aspirin inhibits the reaction [TNF protein results in increased activity of RELA protein]; Aspirin results in decreased localization of and results in decreased activity of RELA protein
Aspirin results in decreased localization of RELA protein
[telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of RELA protein]; Aspirin inhibits the reaction [[Lipopolysaccharides co-treated with TNF protein co-treated with IL1B protein] results in increased activity of RELA protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of RELA protein]
[Pertussis Toxin co-treated with Dithiothreitol] inhibits the reaction [Aspirin inhibits the reaction [Lipopolysaccharides promotes the reaction [[RELA protein co-treated with NFKB1 protein] binds to TNF promoter]]]; Aspirin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] affects the localization of and results in increased phosphorylation of RELA protein]; Aspirin inhibits the reaction [Lipopolysaccharides promotes the reaction [[RELA protein co-treated with NFKB1 protein] binds to TNF promoter]]; Aspirin inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]
Aspirin results in increased localization of RELA protein
CTD PMID:9281604, PMID:10328874, PMID:11826407, PMID:15188000, PMID:15489888, PMID:15770215, PMID:16600694, PMID:17259377, PMID:18786831, PMID:20137092, PMID:20223228, PMID:25449198 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ren renin decreases activity ISO Aspirin results in decreased activity of REN protein CTD PMID:7994448, PMID:19805643 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G RGD1561113 similar to Hypothetical UPF0184 protein C9orf16 homolog increases expression ISO Aspirin results in increased expression of C9ORF16 mRNA CTD PMID:11906190 NCBI chr 3:11,408,076...11,410,907
Ensembl chr 3:11,408,348...11,410,732
JBrowse link
G Rgs7bp regulator of G-protein signaling 7 binding protein affects response to substance ISO RGS7BP polymorphism affects the susceptibility to Aspirin CTD PMID:21457877 NCBI chr 2:35,072,081...35,619,085
Ensembl chr 2:35,077,504...35,104,963
JBrowse link
G Rhog ras homolog family member G decreases expression ISO Aspirin results in decreased expression of RHOG mRNA CTD PMID:15928584 NCBI chr 1:167,336,147...167,347,720
Ensembl chr 1:167,335,248...167,347,671
JBrowse link
G Rnase1 ribonuclease A family member 1, pancreatic increases expression ISO Aspirin results in increased expression of RNASE1 mRNA CTD PMID:11906190
G Rnase6 ribonuclease A family member k6 increases expression ISO Aspirin results in increased expression of RNASE6 mRNA CTD PMID:11906190 NCBI chr15:28,080,307...28,084,269
Ensembl chr15:28,081,004...28,081,465
JBrowse link
G Rnd2 Rho family GTPase 2 increases expression ISO Aspirin results in increased expression of RND2 mRNA CTD PMID:11906190 NCBI chr10:89,376,530...89,380,101
Ensembl chr10:89,376,530...89,380,101
JBrowse link
G Rnf26 ring finger protein 26 increases expression ISO Aspirin results in increased expression of RNF26 mRNA CTD PMID:11906190 NCBI chr 8:48,447,113...48,449,311
Ensembl chr 8:48,447,113...48,449,311
JBrowse link
G Rpl34 ribosomal protein L34 increases expression ISO Aspirin results in increased expression of RPL34 mRNA CTD PMID:15928584 NCBI chr 2:235,850,281...235,854,021
Ensembl chr 2:235,850,334...235,852,708
JBrowse link
G Rpn1 ribophorin I decreases expression ISO Aspirin results in decreased expression of RPN1 mRNA CTD PMID:15928584 NCBI chr 4:119,997,232...120,018,687
Ensembl chr 4:119,997,268...120,018,679
JBrowse link
G Rps16 ribosomal protein S16 increases expression ISO Aspirin results in increased expression of RPS16 mRNA CTD PMID:14976132 NCBI chr 1:85,405,499...85,408,444
Ensembl chr 1:85,405,512...85,408,444
JBrowse link
G Rps19 ribosomal protein S19 increases expression ISO Aspirin results in increased expression of RPS19 mRNA CTD PMID:15456535 NCBI chr 1:81,750,873...81,756,629
Ensembl chr 1:81,750,928...81,756,627
JBrowse link
G Rps27a ribosomal protein S27a increases expression ISO Aspirin results in increased expression of RPS27A mRNA CTD PMID:15928584 NCBI chr14:113,966,163...113,968,440
Ensembl chr14:113,966,611...113,968,268
Ensembl chr 5:113,966,611...113,968,268
JBrowse link
G Rps6 ribosomal protein S6 decreases phosphorylation ISO Aspirin results in decreased phosphorylation of RPS6 protein CTD PMID:23363784 NCBI chr 5:105,197,821...105,200,681
Ensembl chr 5:105,197,857...105,200,148
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions ISO Aspirin results in decreased phosphorylation of and results in decreased activity of RPS6KB1 protein CTD PMID:10993886 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 affects response to substance ISO HLA-DRB1 gene SNP affects the susceptibility to Aspirin CTD PMID:20485159 NCBI chr20:4,087,621...4,097,190
Ensembl chr20:4,087,618...4,097,190
JBrowse link
G S100a11 S100 calcium binding protein A11 decreases expression ISO Aspirin results in decreased expression of S100A11 mRNA CTD PMID:15928584 NCBI chr 2:193,863,185...193,868,646
Ensembl chr 2:193,866,951...193,868,502
JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression
decreases expression
ISO Aspirin results in increased expression of S100A4 mRNA
Aspirin results in decreased expression of S100A4 mRNA
CTD PMID:14976132, PMID:20457246 NCBI chr 2:189,997,278...189,999,587
Ensembl chr 2:189,997,129...189,999,604
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 multiple interactions
increases expression
ISO Aspirin promotes the reaction [NFKB1 protein binds to SAT1 promoter]; Aspirin results in increased expression of and results in increased activity of SAT1 protein
Aspirin results in increased expression of SAT1 mRNA
CTD PMID:16262603 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Sbsn suprabasin multiple interactions ISO Aspirin inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY analog results in increased secretion of SBSN protein] CTD PMID:17303692 NCBI chr 1:89,202,527...89,206,994
Ensembl chr 1:89,202,527...89,206,994
JBrowse link
G Scarb1 scavenger receptor class B, member 1 affects expression
increases expression
decreases expression
multiple interactions
ISO Aspirin affects the expression of SCARB1 mRNA
Aspirin results in increased expression of SCARB1 mRNA; Aspirin results in increased expression of SCARB1 protein
Aspirin affects the expression of SCARB1 protein
Aspirin results in decreased expression of SCARB1 mRNA
[Aspirin co-treated with Fenofibrate] results in increased expression of SCARB1 protein; Aspirin inhibits the reaction [Niacin results in increased expression of SCARB1 mRNA]; Aspirin results in decreased expression of and results in decreased activity of SCARB1 protein; Aspirin results in increased expression of and results in increased activity of SCARB1 protein
CTD PMID:15037193, PMID:16816107, PMID:20137092 NCBI chr12:36,694,952...36,761,445
Ensembl chr12:36,694,960...36,761,455
JBrowse link
G Scfd2 sec1 family domain containing 2 increases expression ISO Aspirin results in increased expression of SCFD2 mRNA CTD PMID:11906190 NCBI chr14:36,216,002...36,543,661
Ensembl chr14:36,216,002...36,543,658
JBrowse link
G Scn1b sodium voltage-gated channel beta subunit 1 increases expression ISO Aspirin results in increased expression of SCN1B mRNA CTD PMID:11906190 NCBI chr 1:89,550,738...89,560,469
Ensembl chr 1:89,550,738...89,560,719
JBrowse link
G Sdc4 syndecan 4 decreases expression ISO Aspirin results in decreased expression of SDC4 mRNA CTD PMID:15928584 NCBI chr 3:160,872,503...160,891,190
Ensembl chr 3:160,872,503...160,891,190
JBrowse link
G Sds serine dehydratase increases expression ISO Aspirin results in increased expression of SDS mRNA CTD PMID:11906190 NCBI chr12:41,620,429...41,627,741
Ensembl chr12:41,620,393...41,627,741
JBrowse link
G Sec13 SEC13 homolog, nuclear pore and COPII coat complex component decreases expression ISO Aspirin results in decreased expression of SEC13 mRNA CTD PMID:15928584 NCBI chr 4:145,686,186...145,699,577
Ensembl chr 4:145,686,193...145,699,577
JBrowse link
G Selenom selenoprotein M increases expression ISO Aspirin results in increased expression of SELENOM mRNA CTD PMID:11906190 NCBI chr14:83,752,393...83,754,975
Ensembl chr14:83,752,393...83,754,973
JBrowse link
G Sell selectin L decreases expression ISO Aspirin results in decreased expression of SELL protein CTD PMID:12147693 NCBI chr13:82,369,820...82,387,774
Ensembl chr13:82,369,493...82,387,631
JBrowse link
G Selp selectin P decreases expression
multiple interactions
increases expression
ISO Aspirin results in decreased expression of SELP protein
Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of SELP protein]; Glucose inhibits the reaction [Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of SELP protein]]
Aspirin results in increased expression of SELP protein
CTD PMID:15140583, PMID:15381054, PMID:16756193, PMID:17543677, PMID:18413191 NCBI chr13:82,428,914...82,464,629
Ensembl chr13:82,429,063...82,464,628
JBrowse link
G Serpina1 serpin family A member 1 multiple interactions ISO Aspirin inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY analog results in increased secretion of SERPINA1 protein] CTD PMID:17303692 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265
JBrowse link
G Serpina3m serpin family A member 3M decreases expression
increases expression
ISO Aspirin results in decreased expression of SERPINA3 mRNA
Aspirin results in increased expression of SERPINA3 mRNA
CTD PMID:11906190, PMID:15456535 NCBI chr 6:127,808,785...127,816,067
Ensembl chr 6:127,808,785...127,816,055
JBrowse link
G Serpinb1a serpin family B member 1A decreases expression ISO Aspirin results in decreased expression of SERPINB1 mRNA CTD PMID:14976132 NCBI chr17:32,903,089...32,911,498
Ensembl chr17:32,904,119...32,911,495
JBrowse link
G Serpinb2 serpin family B member 2 decreases expression ISO Aspirin results in decreased expression of SERPINB2 mRNA CTD PMID:15456535 NCBI chr13:27,449,907...27,463,015
Ensembl chr13:27,449,934...27,463,010
JBrowse link
G Serpinb5 serpin family B member 5 increases expression ISO Aspirin results in increased expression of SERPINB5 protein CTD PMID:16546864 NCBI chr13:26,903,052...26,923,250
Ensembl chr13:26,903,052...26,923,250
JBrowse link
G Sfpq splicing factor proline and glutamine rich decreases expression EXP Aspirin results in decreased expression of SFPQ mRNA CTD PMID:12800193 NCBI chr 5:145,079,803...145,088,517
Ensembl chr 5:145,079,803...145,088,498
JBrowse link
G Sftpd surfactant protein D increases expression ISO Aspirin results in increased expression of SFTPD mRNA CTD PMID:15456535 NCBI chr16:18,753,535...18,766,100
Ensembl chr16:18,745,458...18,766,174
JBrowse link
G Si sucrase-isomaltase increases activity
decreases activity
ISO
EXP
Aspirin results in increased activity of SI protein
Aspirin results in decreased activity of SI protein
CTD PMID:9399670, PMID:18604318 NCBI chr 2:170,220,794...170,301,348
Ensembl chr 2:170,221,245...170,301,348
JBrowse link
G Siah2 siah E3 ubiquitin protein ligase 2 decreases expression ISO Aspirin results in decreased expression of SIAH2 mRNA CTD PMID:15928584 NCBI chr 2:148,874,151...148,891,900
Ensembl chr 2:148,874,151...148,891,900
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO Aspirin inhibits the reaction [Everolimus results in decreased expression of SIRT1 protein]; Aspirin inhibits the reaction [Paclitaxel results in decreased expression of SIRT1 protein]; Aspirin inhibits the reaction [Sirolimus results in decreased expression of SIRT1 protein] CTD PMID:19520256 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc16a1 solute carrier family 16 member 1 multiple interactions
decreases expression
ISO Aspirin affects the reaction [SLC16A1 protein results in increased uptake of Butyrates]
Aspirin results in decreased expression of SLC16A1 mRNA
CTD PMID:11906190, PMID:19023563 NCBI chr 2:207,108,552...207,129,352
Ensembl chr 2:207,108,552...207,128,554
JBrowse link
G Slc22a2 solute carrier family 22 member 2 affects response to substance ISO SLC22A2 polymorphism affects the susceptibility to Aspirin CTD PMID:21346370 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc22a25 solute carrier family 22, member 25 decreases activity ISO Aspirin results in decreased activity of SLC22A9 protein CTD PMID:12388633 NCBI chr 1:224,596,886...224,698,512
Ensembl chr 1:224,596,887...224,698,514
JBrowse link
G Slc22a6 solute carrier family 22 member 6 decreases activity ISO Aspirin results in decreased activity of SLC22A6 protein CTD PMID:12388633 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
G Slc22a7 solute carrier family 22 member 7 decreases activity ISO Aspirin results in decreased activity of SLC22A7 protein CTD PMID:12388633 NCBI chr 9:16,925,321...16,931,119
Ensembl chr 9:16,924,520...16,931,766
JBrowse link
G Slc22a8 solute carrier family 22 member 8 increases expression ISO Aspirin results in increased expression of SLC22A8 mRNA CTD PMID:11906190 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
G Slc25a5 solute carrier family 25 member 5 increases expression EXP Aspirin results in increased expression of SLC25A5 mRNA CTD PMID:8554334 NCBI chr  X:123,404,570...123,407,637
Ensembl chr  X:123,404,518...123,407,645
JBrowse link
G Slc6a12 solute carrier family 6 member 12 affects response to substance ISO SLC6A12 polymorphism affects the susceptibility to Aspirin CTD PMID:20597903 NCBI chr 4:153,921,199...153,941,333
Ensembl chr 4:153,921,115...153,941,391
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor decreases expression ISO Aspirin results in decreased expression of SLPI mRNA CTD PMID:15928584 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link
G Smap2 small ArfGAP2 affects response to substance ISO SMAP2 protein affects the susceptibility to Aspirin CTD PMID:20831471 NCBI chr 5:139,885,321...139,931,366
Ensembl chr 5:139,885,326...139,931,366
JBrowse link
G Smc4 structural maintenance of chromosomes 4 decreases expression ISO Aspirin results in decreased expression of SMC4 mRNA CTD PMID:11906190 NCBI chr 2:165,600,934...165,629,415
Ensembl chr 2:165,601,007...165,629,415
JBrowse link
G Smurf2 SMAD specific E3 ubiquitin protein ligase 2 increases expression ISO Aspirin results in increased expression of SMURF2 mRNA CTD PMID:15928584 NCBI chr10:95,018,050...95,118,107
Ensembl chr10:95,018,059...95,062,987
JBrowse link
G Snca synuclein alpha decreases expression ISO Aspirin results in decreased expression of SNCA mRNA CTD PMID:21353610 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Socs2 suppressor of cytokine signaling 2 increases expression
multiple interactions
ISO Aspirin results in increased expression of SOCS2 mRNA
butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [Aspirin results in increased expression of SOCS2 mRNA]; SOCS2 affects the reaction [Aspirin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]
CTD PMID:16415877 NCBI chr 7:36,495,496...36,500,878
Ensembl chr 7:36,495,480...36,499,784
JBrowse link
G Sod2 superoxide dismutase 2 decreases expression
multiple interactions
increases expression
ISO
EXP
Aspirin results in decreased expression of SOD2 mRNA
rebamipide promotes the reaction [Aspirin results in increased expression of SOD2 protein]
CTD PMID:21353610, PMID:22653900 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Spag6 sperm associated antigen 6 increases expression ISO Aspirin results in increased expression of SPAG6 mRNA CTD PMID:11906190 NCBI chr17:85,382,314...85,437,976
Ensembl chr17:85,382,116...85,437,975
JBrowse link
G Sparc secreted protein acidic and cysteine rich multiple interactions ISO Aspirin inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY analog results in increased secretion of SPARC protein] CTD PMID:17303692 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
G Spp1 secreted phosphoprotein 1 affects expression EXP Aspirin affects the expression of SPP1 mRNA CTD PMID:12800193 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 decreases expression ISO Aspirin results in decreased expression of SPTAN1 mRNA CTD PMID:15456535, PMID:15928584 NCBI chr 3:8,534,437...8,599,259
Ensembl chr 3:8,534,440...8,599,260
JBrowse link
G Srpx sushi-repeat-containing protein, X-linked decreases expression ISO Aspirin results in decreased expression of SRPX mRNA CTD PMID:15456535 NCBI chr  X:14,146,618...14,220,756
Ensembl chr  X:14,150,038...14,220,662
JBrowse link
G Ssr3 signal sequence receptor subunit 3 increases expression ISO Aspirin results in increased expression of SSR3 mRNA CTD PMID:15456535 NCBI chr 2:156,010,997...156,023,853
Ensembl chr 2:156,011,002...156,014,527
JBrowse link
G Stambp Stam binding protein increases expression ISO Aspirin results in increased expression of STAMBP mRNA CTD PMID:15928584 NCBI chr 4:115,249,343...115,277,340
Ensembl chr 4:115,249,351...115,275,068
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
decreases phosphorylation
decreases expression
ISO IL6 protein inhibits the reaction [Aspirin results in decreased expression of STAT3 protein modified form]
Aspirin results in decreased phosphorylation of STAT3 protein
Aspirin results in decreased expression of STAT3 mRNA; Aspirin results in decreased expression of STAT3 protein modified form
CTD PMID:11906190, PMID:19595669, PMID:20886344 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Stat5b signal transducer and activator of transcription 5B decreases expression ISO Aspirin results in decreased expression of STAT5B mRNA CTD PMID:15928584 NCBI chr10:88,686,207...88,712,313
Ensembl chr10:88,686,207...88,754,829
JBrowse link
G Stat6 signal transducer and activator of transcription 6 multiple interactions ISO Aspirin inhibits the reaction [IL4 results in increased activity of STAT6 protein]; Aspirin inhibits the reaction [IL4 results in increased phosphorylation of STAT6 protein] CTD PMID:19767084 NCBI chr 7:70,946,228...70,963,542
Ensembl chr 7:70,946,228...70,964,484
JBrowse link
G Stk10 serine/threonine kinase 10 affects response to substance ISO STK10 polymorphism affects the susceptibility to Aspirin CTD PMID:21905501 NCBI chr10:17,420,964...17,521,810
Ensembl chr10:17,421,075...17,519,706
JBrowse link
G Strn4 striatin 4 increases expression ISO Aspirin results in increased expression of STRN4 mRNA CTD PMID:11906190 NCBI chr 1:78,739,930...78,765,696
Ensembl chr 1:78,735,678...78,765,692
JBrowse link
G Stxbp1 syntaxin binding protein 1 affects expression EXP Aspirin affects the expression of STXBP1 mRNA CTD PMID:12800193 NCBI chr 3:11,823,779...11,885,479
Ensembl chr 3:11,823,785...11,885,417
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 decreases expression ISO Aspirin results in decreased expression of SUMO1 mRNA CTD PMID:11906190 NCBI chr 9:66,453,428...66,483,614
Ensembl chr 9:66,453,438...66,483,614
JBrowse link
G Sumo3 small ubiquitin-like modifier 3 increases expression ISO Aspirin results in increased expression of SUMO3 mRNA CTD PMID:11906190 NCBI chr20:11,726,488...11,737,050
Ensembl chr20:11,726,497...11,737,050
JBrowse link
G Sun2 Sad1 and UNC84 domain containing 2 increases expression ISO Aspirin results in increased expression of SUN2 mRNA CTD PMID:11906190 NCBI chr 7:120,950,391...120,967,583
Ensembl chr 7:120,951,560...120,967,490
JBrowse link
G Tacc3 transforming, acidic coiled-coil containing protein 3 decreases expression ISO Aspirin results in decreased expression of TACC3 mRNA CTD PMID:15928584 NCBI chr14:82,336,283...82,350,069
Ensembl chr14:82,336,324...82,347,679
JBrowse link
G Taf6 TATA-box binding protein associated factor 6 decreases expression ISO Aspirin results in decreased expression of TAF6 mRNA CTD PMID:11906190 NCBI chr12:19,320,269...19,328,706
Ensembl chr12:19,320,271...19,328,637
JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member affects response to substance ISO TAP2 SNP affects the susceptibility to Aspirin CTD PMID:21796142 NCBI chr20:3,995,544...4,009,587
Ensembl chr20:3,995,544...4,009,587
JBrowse link
G Tbc1d10b TBC1 domain family, member 10b increases expression ISO Aspirin results in increased expression of TBC1D10B mRNA CTD PMID:11906190 NCBI chr 1:198,641,018...198,652,674
Ensembl chr 1:198,641,018...198,652,674
JBrowse link
G Tbl1x transducin (beta)-like 1 X-linked decreases expression ISO Aspirin results in decreased expression of TBL1X mRNA CTD PMID:15928584 NCBI chr  X:44,959,883...44,988,551
Ensembl chr  X:44,830,849...44,988,551
JBrowse link
G Tbx21 T-box transcription factor 21 affects response to substance ISO TBX21 SNP affects the susceptibility to Aspirin CTD PMID:15806396 NCBI chr10:85,032,799...85,049,331
Ensembl chr10:85,032,799...85,049,331
JBrowse link
G Tbxa2r thromboxane A2 receptor affects response to substance
decreases response to substance
ISO TBXA2R gene SNP affects the susceptibility to Aspirin; TBXA2R polymorphism affects the susceptibility to Aspirin
TBXA2R SNP results in decreased susceptibility to Aspirin
CTD PMID:17245331, PMID:20485159, PMID:21070398 NCBI chr 7:11,253,153...11,259,233
Ensembl chr 7:11,253,180...11,257,977
JBrowse link
G Tbxas1 thromboxane A synthase 1 affects response to substance ISO TBXAS1 polymorphism affects the susceptibility to Aspirin CTD PMID:21449675 NCBI chr 4:66,624,181...66,846,745
Ensembl chr 4:66,670,618...66,846,805
JBrowse link
G Tcf4 transcription factor 4 multiple interactions
decreases activity
ISO TCF4 protein promotes the reaction [Aspirin results in increased susceptibility to TNFSF10 protein]
Aspirin results in decreased activity of TCF4 protein
CTD PMID:11593435, PMID:21171083 NCBI chr18:65,285,320...65,507,983
Ensembl chr18:65,155,685...65,507,977
JBrowse link
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 increases expression ISO Aspirin results in increased expression of TCIRG1 mRNA CTD PMID:11906190 NCBI chr 1:219,126,687...219,139,466
Ensembl chr 1:219,127,602...219,139,464
JBrowse link
G Tert telomerase reverse transcriptase increases expression ISO Aspirin results in increased expression of TERT mRNA CTD PMID:20457246 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tf transferrin multiple interactions ISO Aspirin inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY analog results in increased secretion of TF protein] CTD PMID:17303692 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tfe3 transcription factor binding to IGHM enhancer 3 decreases expression ISO Aspirin results in decreased expression of TFE3 mRNA CTD PMID:15928584 NCBI chr  X:15,574,579...15,587,826
Ensembl chr  X:15,575,934...15,587,419
JBrowse link
G Tff2 trefoil factor 2 multiple interactions EXP [Aspirin co-treated with Hydrochloric Acid] results in increased expression of TFF2 mRNA CTD PMID:9726391 NCBI chr20:9,872,669...9,876,008
Ensembl chr20:9,872,680...9,876,008
JBrowse link
G Tfg trafficking from ER to golgi regulator increases expression ISO Aspirin results in increased expression of TFG mRNA CTD PMID:15928584 NCBI chr11:46,180,189...46,206,723
Ensembl chr11:46,179,940...46,206,721
JBrowse link
G Tgfa transforming growth factor alpha multiple interactions
decreases expression
EXP [Aspirin co-treated with Hydrochloric Acid] results in increased expression of TGFA mRNA
Aspirin results in decreased expression of TGFA mRNA
CTD PMID:9726391, PMID:12231391 NCBI chr 4:117,961,877...118,045,923
Ensembl chr 4:117,962,319...118,046,344
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression
multiple interactions
increases response to substance
ISO
EXP
Aspirin results in decreased expression of TGFB1 mRNA
Aspirin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein]; Aspirin inhibits the reaction [Streptozocin results in increased expression of TGFB1 mRNA]
TGFB1 promoter SNP results in increased susceptibility to Aspirin
CTD PMID:12566377, PMID:14586741, PMID:15928584, PMID:19138248, PMID:21360558 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 decreases expression ISO Aspirin results in decreased expression of TGIF1 mRNA CTD PMID:15928584 NCBI chr 9:119,181,079...119,190,698
Ensembl chr 9:119,181,083...119,190,698
JBrowse link
G Thbs1 thrombospondin 1 increases expression
multiple interactions
ISO Aspirin results in increased expression of THBS1 mRNA
Aspirin inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY analog results in increased secretion of THBS1 protein]
CTD PMID:15928584, PMID:17303692 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Timm17b translocase of inner mitochondrial membrane 17b increases expression ISO Aspirin results in increased expression of TIMM17B mRNA CTD PMID:11906190 NCBI chr  X:15,441,369...15,448,452
Ensembl chr  X:15,441,651...15,448,403
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
increases secretion
ISO Aspirin results in increased expression of TIMP1 mRNA
Aspirin results in increased secretion of TIMP1 protein
CTD PMID:18971601, PMID:19462226 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 decreases expression
increases expression
ISO Aspirin results in decreased expression of TIMP2 mRNA
Aspirin results in increased expression of TIMP2 mRNA
CTD PMID:15928584, PMID:18971601 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Tlr3 toll-like receptor 3 affects response to substance ISO TLR3 polymorphism affects the susceptibility to Aspirin CTD PMID:21461252 NCBI chr16:50,016,466...50,031,011
Ensembl chr16:50,016,857...50,031,214
JBrowse link
G Tmed9 transmembrane p24 trafficking protein 9 increases expression ISO Aspirin results in increased expression of TMED9 mRNA CTD PMID:11906190 NCBI chr17:9,560,735...9,565,249
Ensembl chr17:9,560,761...9,565,249
JBrowse link
G Tmem205 transmembrane protein 205 increases expression EXP Aspirin results in increased expression of TMEM205 mRNA CTD PMID:12800193 NCBI chr 8:22,932,175...22,937,953
Ensembl chr 8:22,932,175...22,937,909
JBrowse link
G Tmod4 tropomodulin 4 increases expression ISO Aspirin results in increased expression of TMOD4 mRNA CTD PMID:11906190 NCBI chr 2:196,294,990...196,299,896
Ensembl chr 2:196,295,069...196,299,896
JBrowse link
G Tmsb4x thymosin beta 4, X-linked increases expression ISO Aspirin results in increased expression of TMSB4X mRNA CTD PMID:15928584 NCBI chr  X:28,593,405...28,617,267
Ensembl chr  X:28,593,405...28,595,395
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
decreases expression
affects secretion
affects response to substance
ISO
EXP
[Aspirin co-treated with IL1A] results in increased expression of TNF mRNA; Aspirin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Aspirin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Aspirin inhibits the reaction [TNF protein results in increased activity of [NFKB1 protein binds to RELA protein]]; Aspirin inhibits the reaction [TNF protein results in increased activity of CHUK protein]; Aspirin inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]; Aspirin inhibits the reaction [TNF protein results in increased activity of RELA protein]; Aspirin inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; Aspirin inhibits the reaction [TNF protein results in increased expression of CCND1 protein]; Aspirin inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]; Aspirin inhibits the reaction [TNF results in increased degradation of NFKBIA protein]; Aspirin inhibits the reaction [TNF results in increased expression of CCL2 mRNA]; Aspirin inhibits the reaction [TNF results in increased expression of CX3CL1 mRNA]; Aspirin inhibits the reaction [TNF results in increased expression of CX3CL1 protein]; Aspirin inhibits the reaction [TNF results in increased expression of CXCL8 mRNA]; Aspirin inhibits the reaction [TNF results in increased expression of PTGS2 mRNA]; Aspirin inhibits the reaction [TNF results in increased expression of PTGS2 protein]; Aspirin inhibits the reaction [TNF results in increased phosphorylation of NFKBIA protein]; Aspirin inhibits the reaction [TNF results in increased phosphorylation of NFKBIB protein]; Aspirin inhibits the reaction [TNF results in increased secretion of CCL2 protein]; Aspirin inhibits the reaction [TNF results in increased secretion of CXCL8 protein]; Aspirin promotes the reaction [Salmonella Vaccines results in increased expression of TNF protein]
Aspirin results in increased expression of TNF protein
[Telmisartan co-treated with Aspirin] inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]]; Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]]; Aspirin inhibits the reaction [[Lipopolysaccharides co-treated with TNF protein co-treated with IL1B protein] results in increased activity of NFKB1 protein]; Aspirin inhibits the reaction [[Lipopolysaccharides co-treated with TNF protein co-treated with IL1B protein] results in increased activity of RELA protein]; Aspirin inhibits the reaction [Azoxymethane results in increased expression of TNF mRNA]; Aspirin inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Aspirin promotes the reaction [Acetic Acid results in increased expression of TNF protein]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF mRNA]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of TNF protein]; Bee Venoms inhibits the reaction [Aspirin results in increased expression of TNF protein]; lipopolysaccharide, Helicobacter pylori inhibits the reaction [Aspirin results in increased expression of TNF protein]; Ranitidine inhibits the reaction [Aspirin results in increased expression of TNF protein]
Aspirin results in decreased expression of TNF mRNA
[Aspirin co-treated with Lipopolysaccharides] results in increased secretion of TNF protein; [Pertussis Toxin co-treated with Dithiothreitol] inhibits the reaction [Aspirin inhibits the reaction [Lipopolysaccharides promotes the reaction [[RELA protein co-treated with NFKB1 protein] binds to TNF promoter]]]; [Pertussis Toxin co-treated with Dithiothreitol] inhibits the reaction [Aspirin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; Aspirin inhibits the reaction [Acetaminophen results in increased expression of TNF mRNA]; Aspirin inhibits the reaction [Lipopolysaccharides promotes the reaction [[RELA protein co-treated with NFKB1 protein] binds to TNF promoter]]; Aspirin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Aspirin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Aspirin inhibits the reaction [TNF protein results in increased abundance of Dinoprostone]; Aspirin inhibits the reaction [TNF protein results in increased secretion of Dinoprostone]; SOCS2 affects the reaction [Aspirin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]
Aspirin affects the secretion of TNF protein
TNF gene SNP affects the susceptibility to Aspirin; TNF polymorphism affects the susceptibility to Aspirin
CTD PMID:9281604, PMID:10328874, PMID:11376495, PMID:11826407, PMID:12045164, PMID:14742690, PMID:15024038, PMID:15036249, PMID:15136050, PMID:15379866, PMID:15489888, PMID:16413386, PMID:16415877, PMID:17328244, PMID:17516296, PMID:19164858, PMID:19493461, PMID:20043115, PMID:20223228, PMID:20485159, PMID:21353610, PMID:21893697, PMID:22039321, PMID:30885738 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip6 TNF alpha induced protein 6 increases expression ISO Aspirin results in increased expression of TNFAIP6 mRNA CTD PMID:15928584 NCBI chr 3:37,545,238...37,564,704
Ensembl chr 3:37,545,238...37,564,699
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases expression ISO Aspirin results in increased expression of TNFRSF1A mRNA CTD PMID:20457246 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf25 TNF receptor superfamily member 25 increases expression ISO Aspirin results in increased expression of TNFRSF25 mRNA CTD PMID:20457246 NCBI chr 5:169,288,419...169,293,137
Ensembl chr 5:169,288,871...169,293,137
JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions
increases response to substance
ISO
EXP
[Aspirin co-treated with TNFSF10 protein] results in decreased expression of BIRC5 protein; [Aspirin co-treated with TNFSF10 protein] results in increased activity of CASP8 protein; [Aspirin co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP3 protein; [Aspirin co-treated with TNFSF10 protein] results in increased cleavage of and results in increased activity of CASP8 protein; [Aspirin co-treated with TNFSF10 protein] results in increased cleavage of BID protein; [Aspirin co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein; [TNFSF10 protein co-treated with Aspirin] results in increased cleavage of and results in increased activity of CASP3 protein; [TNFSF10 protein co-treated with Aspirin] results in increased cleavage of and results in increased activity of CASP9 protein; [TNFSF10 protein co-treated with Aspirin] results in increased cleavage of CASP8 protein; Aspirin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]; BCL2 protein inhibits the reaction [[TNFSF10 protein co-treated with Aspirin] results in increased cleavage of and results in increased activity of CASP3 protein]; BCL2 protein inhibits the reaction [[TNFSF10 protein co-treated with Aspirin] results in increased cleavage of and results in increased activity of CASP9 protein]; BCL2 protein inhibits the reaction [Aspirin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]; TCF4 protein promotes the reaction [Aspirin results in increased susceptibility to TNFSF10 protein]
Aspirin inhibits the reaction [Azoxymethane results in increased expression of TNFSF10 mRNA]
CTD PMID:16199534, PMID:18483385, PMID:20043115, PMID:21171083 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tnni3 troponin I3, cardiac type increases expression ISO Aspirin results in increased expression of TNNI3 mRNA CTD PMID:11906190 NCBI chr 1:72,882,806...72,886,490
Ensembl chr 1:72,882,806...72,886,488
JBrowse link
G Tns3 tensin 3 increases expression ISO Aspirin results in increased expression of TNS3 mRNA CTD PMID:11906190 NCBI chr14:88,673,922...88,907,874
Ensembl chr14:88,673,881...88,886,198
JBrowse link
G Tob1 transducer of ErbB-2.1 decreases expression ISO Aspirin results in decreased expression of TOB1 mRNA CTD PMID:11906190 NCBI chr10:81,913,689...81,915,727
Ensembl chr10:81,913,689...81,915,716
JBrowse link
G Top3b DNA topoisomerase III beta increases expression ISO Aspirin results in increased expression of TOP3B mRNA CTD PMID:11906190 NCBI chr11:88,346,305...88,374,896
Ensembl chr11:88,346,313...88,374,679
JBrowse link
G Tp53 tumor protein p53 increases acetylation
multiple interactions
increases expression
ISO Aspirin results in increased acetylation of TP53 protein
Aspirin inhibits the reaction [sodium bichromate results in increased expression of TP53 protein]
Aspirin results in increased expression of TRP53 protein
Aspirin results in increased expression of TP53 protein
CTD PMID:10942736, PMID:12535653, PMID:16880202, PMID:19212664 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp53i13 tumor protein p53 inducible protein 13 increases expression ISO Aspirin results in increased expression of TP53I13 mRNA CTD PMID:11906190 NCBI chr10:62,650,640...62,655,327
Ensembl chr10:62,650,719...62,655,362
JBrowse link
G Tpd52l2 TPD52 like 2 decreases expression ISO Aspirin results in decreased expression of TPD52L2 mRNA CTD PMID:15928584 NCBI chr 3:176,989,333...177,009,425
Ensembl chr 3:176,989,672...177,008,419
JBrowse link
G Tra2b transformer 2 beta homolog increases expression
decreases expression
ISO
EXP
Aspirin results in increased expression of TRA2B mRNA
Aspirin results in decreased expression of TRA2B mRNA
CTD PMID:12800193, PMID:15928584 NCBI chr11:82,373,828...82,392,208
Ensembl chr11:82,373,870...82,392,083
JBrowse link
G Traf6 TNF receptor associated factor 6 increases expression ISO Aspirin results in increased expression of TRAF6 mRNA CTD PMID:11906190 NCBI chr 3:91,252,829...91,271,607
Ensembl chr 3:91,252,829...91,271,607
JBrowse link
G Trappc6a trafficking protein particle complex 6A increases expression ISO Aspirin results in increased expression of TRAPPC6A mRNA CTD PMID:11906190 NCBI chr 1:80,417,514...80,424,429
Ensembl chr 1:80,417,310...80,424,445
JBrowse link
G Trim21 tripartite motif-containing 21 decreases expression ISO Aspirin results in decreased expression of TRIM21 mRNA CTD PMID:15928584 NCBI chr 1:167,686,148...167,708,735
Ensembl chr 1:167,686,173...167,708,714
JBrowse link
G Trit1 tRNA isopentenyltransferase 1 increases expression ISO Aspirin results in increased expression of TRIT1 mRNA CTD PMID:11906190 NCBI chr 5:140,711,943...140,756,893
Ensembl chr 5:140,712,583...140,756,085
JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 increases expression ISO Aspirin results in increased expression of TRPM4 mRNA CTD PMID:11906190 NCBI chr 1:101,293,300...101,323,484
Ensembl chr 1:101,293,409...101,323,960
JBrowse link
G Tsnax translin-associated factor X increases expression ISO Aspirin results in increased expression of TSNAX mRNA CTD PMID:11906190 NCBI chr19:57,771,539...57,785,567
Ensembl chr19:57,771,398...57,785,543
JBrowse link
G Tspan3 tetraspanin 3 decreases expression ISO Aspirin results in decreased expression of TSPAN3 mRNA CTD PMID:15928584 NCBI chr 8:60,806,848...60,830,448
Ensembl chr 8:60,806,849...60,830,448
JBrowse link
G Tuba1a tubulin, alpha 1A decreases expression ISO Aspirin results in decreased expression of TUBA1A mRNA CTD PMID:15928584 NCBI chr 7:140,637,287...140,640,953
Ensembl chr 7:140,637,287...140,640,953
JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases expression ISO Aspirin results in decreased expression of TXNRD1 mRNA CTD PMID:11906190 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Tyk2 tyrosine kinase 2 decreases expression ISO Aspirin results in decreased expression of TYK2 mRNA CTD PMID:15928584 NCBI chr 8:22,118,224...22,149,807
Ensembl chr 8:22,124,560...22,150,005
JBrowse link
G Tymp thymidine phosphorylase multiple interactions
decreases expression
ISO Aspirin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TYMP mRNA]
Aspirin results in decreased expression of TYMP mRNA
CTD PMID:14573775, PMID:15456535 NCBI chr 7:130,342,481...130,347,845
Ensembl chr 7:130,342,483...130,347,587
JBrowse link
G Uba2 ubiquitin-like modifier activating enzyme 2 increases expression ISO Aspirin results in increased expression of UBA2 mRNA CTD PMID:15928584 NCBI chr 1:90,010,681...90,035,522
Ensembl chr 1:90,011,306...90,035,522
JBrowse link
G Ube2a ubiquitin-conjugating enzyme E2A increases expression ISO Aspirin results in increased expression of UBE2A mRNA CTD PMID:15928584 NCBI chr  X:123,486,988...123,497,726
Ensembl chr  X:123,486,989...123,497,726
JBrowse link
G Ube2b ubiquitin-conjugating enzyme E2B increases expression EXP Aspirin results in increased expression of UBE2B mRNA CTD PMID:12800193 NCBI chr10:37,439,947...37,454,867
Ensembl chr10:37,441,284...37,455,022
JBrowse link
G Ube2k ubiquitin-conjugating enzyme E2K increases expression ISO Aspirin results in increased expression of UBE2K mRNA CTD PMID:11906190 NCBI chr14:44,289,247...44,348,691
Ensembl chr14:44,289,247...44,348,691
JBrowse link
G Ube3c ubiquitin protein ligase E3C affects response to substance ISO UBE3C polymorphism affects the susceptibility to Aspirin CTD PMID:20934631 NCBI chr 4:2,505,912...2,606,710
Ensembl chr 4:2,505,909...2,606,655
JBrowse link
G Ube4a ubiquitination factor E4A increases expression ISO Aspirin results in increased expression of UBE4A mRNA CTD PMID:15928584 NCBI chr 8:49,229,713...49,271,894
Ensembl chr 8:49,229,717...49,271,834
JBrowse link
G Ubtd1 ubiquitin domain containing 1 increases expression ISO Aspirin results in increased expression of UBTD1 mRNA CTD PMID:11906190 NCBI chr 1:261,229,347...261,280,543
Ensembl chr 1:261,229,347...261,280,536
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases response to substance EXP UGT1A1 gene mutant form results in increased susceptibility to Aspirin; UGT1A1 protein mutant form results in increased susceptibility to Aspirin CTD PMID:3864191, PMID:6776978 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of Aspirin CTD PMID:15117964 NCBI chr 9:95,285,592...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 affects expression EXP Aspirin affects the expression of UGT1A6 mRNA CTD PMID:12800193 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 increases glucuronidation ISO UGT1A8 protein results in increased glucuronidation of Aspirin CTD PMID:15117964 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ung uracil-DNA glycosylase increases expression ISO Aspirin results in increased expression of UNG mRNA CTD PMID:11906190 NCBI chr12:48,246,593...48,255,547
Ensembl chr12:48,246,569...48,254,822
JBrowse link
G Usp15 ubiquitin specific peptidase 15 increases expression ISO Aspirin results in increased expression of USP15 mRNA CTD PMID:11906190 NCBI chr 7:66,595,707...66,687,707
Ensembl chr 7:66,595,742...66,687,278
JBrowse link
G Vamp1 vesicle-associated membrane protein 1 decreases expression ISO Aspirin results in decreased expression of VAMP1 mRNA CTD PMID:15928584 NCBI chr 4:157,726,941...157,733,644
Ensembl chr 4:157,726,941...157,733,643
JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 decreases expression ISO Aspirin results in decreased expression of VAV1 mRNA CTD PMID:15928584 NCBI chr 9:9,617,551...9,675,167
Ensembl chr 9:9,617,786...9,675,110
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 decreases expression ISO
EXP
Aspirin results in decreased expression of VCAM1 mRNA
Aspirin results in decreased expression of VCAM1 protein
CTD PMID:15456535, PMID:16310244 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vcl vinculin decreases expression ISO Aspirin results in decreased expression of VCL mRNA CTD PMID:11906190 NCBI chr15:3,455,211...3,544,738
Ensembl chr15:3,455,211...3,544,702
JBrowse link
G Vdac1 voltage-dependent anion channel 1 affects expression EXP Aspirin affects the expression of VDAC1 mRNA CTD PMID:12800193 NCBI chr10:37,724,915...37,752,827
Ensembl chr10:37,724,915...37,752,826
JBrowse link
G Vdr vitamin D receptor affects response to substance ISO VDR polymorphism affects the susceptibility to Aspirin CTD PMID:15066917 NCBI chr 7:139,344,452...139,394,138
Ensembl chr 7:139,342,063...139,394,166
JBrowse link
G Vegfa vascular endothelial growth factor A decreases expression
multiple interactions
affects expression
ISO
EXP
Aspirin results in decreased expression of VEGFA
Ampicillin inhibits the reaction [Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]]; Aspirin inhibits the reaction [1,2-Dimethylhydrazine results in increased expression of VEGFA protein]; Aspirin promotes the reaction [Trinitrobenzenesulfonic Acid results in increased expression of VEGFA mRNA]
Aspirin affects the expression of VEGFA mRNA
Aspirin results in decreased expression of VEGFA mRNA
nitroaspirin inhibits the reaction [Aspirin results in decreased expression of VEGFA]
CTD PMID:12231391, PMID:12800193, PMID:15345513, PMID:21893697, PMID:29031619 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vip vasoactive intestinal peptide increases expression ISO Aspirin results in increased expression of VIP protein CTD PMID:14680090 NCBI chr 1:42,169,307...42,177,582
Ensembl chr 1:42,169,501...42,177,582
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 increases response to substance ISO VKORC1 gene SNP results in increased susceptibility to Aspirin CTD PMID:28338108 NCBI chr 1:199,338,785...199,341,306
Ensembl chr 1:199,337,138...199,341,302
JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A decreases expression ISO Aspirin results in decreased expression of VPS4A mRNA CTD PMID:15928584 NCBI chr19:39,230,050...39,243,298
Ensembl chr19:39,229,754...39,243,496
JBrowse link
G Vwa1 von Willebrand factor A domain containing 1 increases expression ISO Aspirin results in increased expression of VWA1 mRNA CTD PMID:15456535 NCBI chr 5:173,216,737...173,221,923
Ensembl chr 5:173,216,741...173,222,440
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 decreases expression ISO Aspirin results in decreased expression of WARS1 mRNA CTD PMID:11906190, PMID:15928584 NCBI chr 6:132,771,026...132,802,262
Ensembl chr 6:132,771,021...132,802,210
JBrowse link
G Wbp2 WW domain binding protein 2 decreases expression ISO Aspirin results in decreased expression of WBP2 mRNA CTD PMID:15928584 NCBI chr10:104,629,563...104,637,906
Ensembl chr10:104,630,573...104,637,823
JBrowse link
G Wif1 Wnt inhibitory factor 1 increases expression ISO Aspirin results in increased expression of WIF1 mRNA CTD PMID:11906190 NCBI chr 7:63,094,955...63,165,158
Ensembl chr 7:63,094,911...63,165,159
JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression
multiple interactions
ISO Aspirin results in decreased expression of XIAP protein
Aspirin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of XIAP protein]
CTD PMID:19595669, PMID:25449198 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 increases expression ISO Aspirin results in increased expression of XRCC3 mRNA; Aspirin results in increased expression of XRCC3 protein CTD PMID:20514442 NCBI chr 6:136,366,917...136,380,751
Ensembl chr 6:136,371,555...136,379,348
JBrowse link
G Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon decreases expression ISO Aspirin results in decreased expression of YWHAE protein CTD PMID:18678619 NCBI chr10:63,884,338...63,921,709
Ensembl chr10:63,884,338...63,921,709
JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta increases expression ISO Aspirin results in increased expression of YWHAQ mRNA CTD PMID:15928584 NCBI chr 6:43,463,294...43,493,816
Ensembl chr 6:43,463,294...43,493,816
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta multiple interactions ISO Aspirin inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY analog results in increased secretion of YWHAZ protein] CTD PMID:17303692 NCBI chr 7:75,573,553...75,598,295
Ensembl chr 7:75,574,967...75,597,276
JBrowse link
G Zfp385a zinc finger protein 385A increases expression ISO Aspirin results in increased expression of ZNF385A mRNA CTD PMID:11906190 NCBI chr 7:144,939,616...144,966,364
Ensembl chr 7:144,939,619...144,966,370
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      biological role 19732
        aetiopathogenetic role 18936
          teratogenic agent 15853
            acetylsalicylic acid 646
              2-acetyloxy-4-pentadecylbenzoic acid 0
              Yosprala 0
              aspirin-based probe AP 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      carboxylic acid 18060
                                        aromatic carboxylic acid 10889
                                          benzoic acids 10858
                                            benzoic acid 3839
                                              hydroxybenzoic acid 3227
                                                monohydroxybenzoic acid 1264
                                                  salicylic acid 740
                                                    acetylsalicylic acid 646
                                                      2-acetyloxy-4-pentadecylbenzoic acid 0
                                                      Yosprala 0
                                                      aspirin-based probe AP 0
paths to the root