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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Urolithin A
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Accession:CHEBI:168442 term browser browse the term
Synonyms:exact_synonym: 3,8-dihydroxybenzo[c]chromen-6-one
 related_synonym: Formula=C13H8O4;   InChI=1S/C13H8O4/c14-7-1-3-9-10-4-2-8(15)6-12(10)17-13(16)11(9)5-7/h1-6,14-15H;   InChIKey=RIUPLDUFZCXCHM-UHFFFAOYSA-N;   SMILES=O1C2=C(C3=C(C=C(O)C=C3)C1=O)C=CC(O)=C2
 xref: CAS:1143-70-0;   Chemspider:4589709;   DrugBank:DB15464;   HMDB:HMDB0013695
 xref_mesh: MESH:C026423
 xref: PMID:27400265


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Urolithin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity ISO 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one results in increased activity of CASP3 protein CTD PMID:23811531 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one results in increased expression of CDKN1A protein CTD PMID:32179165 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one binds to and affects the activity of ESR1 protein CTD PMID:16506809 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one binds to and affects the activity of ESR2 protein CTD PMID:16506809 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Gal galanin and GMAP prepropeptide increases activity ISO 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one results in increased activity of GAL protein CTD PMID:32179165 NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression ISO 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one results in decreased expression of JUN mRNA; 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one results in decreased expression of JUN protein modified form CTD PMID:23811531 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 decreases expression ISO 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one results in decreased expression of MAP3K1 mRNA; 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one results in decreased expression of MAP3K1 protein CTD PMID:23811531 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Mapk11 mitogen-activated protein kinase 11 increases expression ISO 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one results in increased expression of MAPK11 mRNA CTD PMID:23811531 NCBI chr 7:120,218,471...120,225,488
Ensembl chr 7:120,218,478...120,225,395 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one results in increased expression of PPARG protein CTD PMID:23811531 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO 3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-one results in increased expression of TP53 protein CTD PMID:32179165 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
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  CHEBI ontology 19932
    role 19904
      application 19741
        pharmaceutical 19579
          drug 19579
            protective agent 18268
              geroprotector 17409
                Urolithin A 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19932
    subatomic particle 19930
      composite particle 19930
        hadron 19930
          baryon 19930
            nucleon 19930
              atomic nucleus 19930
                atom 19930
                  main group element atom 19876
                    p-block element atom 19876
                      carbon group element atom 19816
                        carbon atom 19812
                          organic molecular entity 19812
                            organic molecule 19764
                              organic cyclic compound 19553
                                organic heterocyclic compound 18905
                                  oxacycle 17908
                                    benzopyran 11984
                                      1-benzopyran 11738
                                        chromenes 4433
                                          chromenone 4377
                                            coumarins 4147
                                              Urolithin A 10
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