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G |
Ccl11 |
C-C motif chemokine ligand 11 |
multiple interactions |
ISO |
fumaric acid inhibits the reaction [TNF protein results in increased expression of CCL11 mRNA]; fumaric acid inhibits the reaction [TNF protein results in increased expression of CCL11 protein] |
CTD |
PMID:23707484 |
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NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
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G |
Ccr3 |
C-C motif chemokine receptor 3 |
multiple interactions |
ISO |
fumaric acid inhibits the reaction [TNF protein results in increased expression of CCR3 protein] |
CTD |
PMID:23707484 |
|
NCBI chr 8:133,026,539...133,040,999
Ensembl chr 8:133,029,625...133,040,997
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G |
Hlcs |
holocarboxylase synthetase |
decreases activity |
ISO |
fumaric acid results in decreased activity of HLCS protein |
CTD |
PMID:26303405 |
|
NCBI chr11:34,357,372...34,537,798
Ensembl chr11:34,352,287...34,526,931
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions |
ISO |
fumaric acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] |
CTD |
PMID:23707484 |
|
NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
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G |
Lepr |
leptin receptor |
affects abundance |
ISO |
LEPR affects the abundance of fumaric acid |
CTD |
PMID:20567778 |
|
NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions |
ISO |
fumaric acid inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein] |
CTD |
PMID:23707484 |
|
NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
fumaric acid inhibits the reaction [TNF protein affects the localization of RELA protein] |
CTD |
PMID:23707484 |
|
NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
fumaric acid inhibits the reaction [TNF protein affects the localization of RELA protein]; fumaric acid inhibits the reaction [TNF protein results in increased expression of CCL11 mRNA]; fumaric acid inhibits the reaction [TNF protein results in increased expression of CCL11 protein]; fumaric acid inhibits the reaction [TNF protein results in increased expression of CCR3 protein]; fumaric acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; fumaric acid inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; fumaric acid inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein] |
CTD |
PMID:23707484 |
|
NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 Ensembl chr20:5,189,390...5,192,000
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
ISO |
fumaric acid inhibits the reaction [TNF protein results in increased expression of VCAM1 protein] |
CTD |
PMID:23707484 |
|
NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
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G |
Casp3 |
caspase 3 |
increases cleavage |
ISO |
diethyl fumarate results in increased cleavage of CASP3 protein |
CTD |
PMID:21105742 |
|
NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage |
ISO |
diethyl fumarate results in increased cleavage of PARP1 protein |
CTD |
PMID:21105742 |
|
NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
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G |
Sptan1 |
spectrin, alpha, non-erythrocytic 1 |
increases cleavage |
ISO |
diethyl fumarate results in increased cleavage of SPTAN1 protein |
CTD |
PMID:21105742 |
|
NCBI chr 3:8,534,437...8,599,259
Ensembl chr 3:8,534,440...8,599,260
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G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions |
EXP |
Dimethyl Fumarate inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] |
CTD |
PMID:30703375 |
|
NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
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G |
Atp6v0d2 |
ATPase H+ transporting V0 subunit D2 |
multiple interactions |
ISO |
Dimethyl Fumarate inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of ATP6V0D2 mRNA] |
CTD |
PMID:30742845 |
|
NCBI chr 5:33,843,591...33,892,446
Ensembl chr 5:33,843,519...33,892,462
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G |
Bach1 |
BTB domain and CNC homolog 1 |
affects localization |
ISO |
Dimethyl Fumarate affects the localization of BACH1 protein |
CTD |
PMID:27277809 |
|
NCBI chr11:27,364,913...27,398,713
Ensembl chr11:27,364,916...27,398,842 Ensembl chr11:27,364,916...27,398,842
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions decreases expression |
ISO |
Acetylcysteine inhibits the reaction [Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; Dimethyl Fumarate inhibits the reaction [IKBKB protein results in increased expression of CCL2 mRNA]; Dimethyl Fumarate inhibits the reaction [TNF protein promotes the reaction [RELA protein binds to CCL2 promoter]]; Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA] Dimethyl Fumarate inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of CCL2 mRNA] Dimethyl Fumarate results in decreased expression of CCL2 mRNA |
CTD |
PMID:26683377 PMID:27277809 |
|
NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
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G |
Cd68 |
Cd68 molecule |
multiple interactions |
ISO |
Dimethyl Fumarate inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of CD68 mRNA] |
CTD |
PMID:27277809 |
|
NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
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G |
Csf1r |
colony stimulating factor 1 receptor |
multiple interactions |
ISO |
Dimethyl Fumarate inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of ATP6V0D2 mRNA]; Dimethyl Fumarate inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of CTSK mRNA] |
CTD |
PMID:30742845 |
|
NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
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G |
Ctsk |
cathepsin K |
multiple interactions |
ISO |
Dimethyl Fumarate inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of CTSK mRNA] |
CTD |
PMID:30742845 |
|
NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446
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G |
Fth1 |
ferritin heavy chain 1 |
increases expression multiple interactions |
ISO |
Dimethyl Fumarate results in increased expression of FTH1 mRNA; Dimethyl Fumarate results in increased expression of FTH1 protein NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of FTH1 mRNA] |
CTD |
PMID:28289076 |
|
NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
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G |
Ftl1 |
ferritin light chain 1 |
increases expression multiple interactions |
ISO |
Dimethyl Fumarate results in increased expression of FTL mRNA; Dimethyl Fumarate results in increased expression of FTL protein NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of FTL mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of FTL protein] |
CTD |
PMID:28289076 |
|
NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions increases expression |
ISO EXP |
NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of GCLC mRNA] Dimethyl Fumarate results in increased expression of GCLC protein |
CTD |
PMID:27277809 PMID:30248482 |
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NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions increases expression |
ISO EXP |
NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of GCLM mRNA] Dimethyl Fumarate results in increased expression of GCLM protein |
CTD |
PMID:27277809 |
|
NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
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G |
Gpx4 |
glutathione peroxidase 4 |
increases metabolic processing |
ISO |
Dimethyl Fumarate results in increased metabolism of GPX4 protein |
CTD |
PMID:29917289 |
|
NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
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G |
Gsr |
glutathione-disulfide reductase |
increases expression multiple interactions |
EXP ISO |
Dimethyl Fumarate results in increased expression of GSR protein NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of GSR mRNA] |
CTD |
PMID:27277809 |
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NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
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G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
ISO EXP |
Dimethyl Fumarate results in increased expression of HMOX1 mRNA; Dimethyl Fumarate results in increased expression of HMOX1 protein Acetylcysteine inhibits the reaction [Dimethyl Fumarate results in increased expression of HMOX1 protein]; HMOX1 protein inhibits the reaction [Dimethyl Fumarate inhibits the reaction [Lipopolysaccharides results in increased abundance of Dinoprostone]]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of HMOX1 protein] [Dimethyl Fumarate results in decreased abundance of Glutathione] which results in increased expression of HMOX1 protein; [Dimethyl Fumarate results in increased expression of HMOX1 protein] which results in decreased susceptibility to PDGFB protein; Glutathione inhibits the reaction [Dimethyl Fumarate results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of HMOX1 protein]; SB 203580 inhibits the reaction [Dimethyl Fumarate results in increased expression of HMOX1 protein] |
CTD |
PMID:20961405 PMID:23942037 PMID:26683377 PMID:27277809 PMID:28790194 PMID:29950142 |
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NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions decreases expression |
ISO |
Acetylcysteine inhibits the reaction [Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]]; Dimethyl Fumarate inhibits the reaction [TNF protein promotes the reaction [RELA protein binds to ICAM1 promoter]]; Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] Dimethyl Fumarate results in decreased expression of ICAM1 mRNA |
CTD |
PMID:26683377 |
|
NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
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G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
Dimethyl Fumarate inhibits the reaction [nickel sulfate results in increased secretion of IFNG protein] Dimethyl Fumarate inhibits the reaction [IFNG protein results in increased abundance of Dinoprostone]; Dimethyl Fumarate inhibits the reaction [IFNG protein results in increased abundance of Nitrites]; tin protoporphyrin IX inhibits the reaction [Dimethyl Fumarate inhibits the reaction [IFNG protein results in increased abundance of Nitrites]] |
CTD |
PMID:15663561 PMID:23942037 |
|
NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
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G |
Ikbkb |
inhibitor of nuclear factor kappa B kinase subunit beta |
multiple interactions |
ISO |
Dimethyl Fumarate inhibits the reaction [IKBKB protein results in increased expression of CCL2 mRNA]; Dimethyl Fumarate inhibits the reaction [IKBKB protein results in increased expression of TNF mRNA] |
CTD |
PMID:26683377 |
|
NCBI chr16:74,177,233...74,230,809
Ensembl chr16:74,177,215...74,230,815
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G |
Il6r |
interleukin 6 receptor |
decreases expression |
ISO |
Dimethyl Fumarate results in decreased expression of IL6R protein |
CTD |
PMID:28134847 |
|
NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
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G |
Lamp2 |
lysosomal-associated membrane protein 2 |
multiple interactions increases expression |
ISO |
NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of LAMP2 protein alternative form] |
CTD |
PMID:29950142 |
|
NCBI chr X:124,722,628...124,766,079
Ensembl chr X:124,722,628...124,766,044
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G |
Mt-co3 |
mitochondrially encoded cytochrome c oxidase III |
increases expression multiple interactions |
ISO |
Dimethyl Fumarate results in increased expression of COX3 mRNA NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of COX3 mRNA] |
CTD |
PMID:27277809 |
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NCBI chr MT:8,599...9,382
Ensembl chr MT:8,599...9,382
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G |
Mt-cyb |
mitochondrially encoded cytochrome b |
multiple interactions increases expression |
ISO |
NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of CYTB mRNA] |
CTD |
PMID:27277809 |
|
NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278
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G |
Mt-nd1 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 |
multiple interactions increases expression |
ISO |
NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of ND1 mRNA] |
CTD |
PMID:27277809 |
|
NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694
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G |
Mt-nd2 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 |
multiple interactions increases expression |
ISO |
NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of ND2 mRNA] |
CTD |
PMID:27277809 |
|
NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942
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G |
Mt-nd5 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5 |
multiple interactions increases expression |
ISO |
NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of ND5 mRNA] |
CTD |
PMID:27277809 |
|
NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565
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G |
Mterf1 |
mitochondrial transcription termination factor 1 |
increases expression multiple interactions |
ISO |
Dimethyl Fumarate results in increased expression of MTERF1A mRNA NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of MTERF1A mRNA] |
CTD |
PMID:27277809 |
|
NCBI chr 4:27,365,310...27,372,374
Ensembl chr 4:27,365,376...27,372,372
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G |
Mterf3 |
mitochondrial transcription termination factor 3 |
increases expression multiple interactions |
ISO |
Dimethyl Fumarate results in increased expression of MTERF3 mRNA NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of MTERF3 mRNA] |
CTD |
PMID:27277809 |
|
NCBI chr 7:71,275,544...71,293,842
Ensembl chr 7:71,273,275...71,293,823
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G |
Nfe2l2 |
nuclear factor, erythroid 2-like 2 |
multiple interactions increases expression affects localization |
ISO |
NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of COX3 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of CYTB mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of GCLC mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of GCLM mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of GSR mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of LAMP2 protein alternative form]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of MTERF1A mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of MTERF3 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of ND1 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of ND2 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of ND5 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of POLG2 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of POLRMT mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of SQSTM1 protein]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of SSBP1 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of TFAM mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of TFB1M mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of TFB2M mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of TWNK mRNA]; NFE2L2 protein inhibits the reaction [Dimethyl Fumarate inhibits the reaction [Lipopolysaccharides results in increased abundance of Dinoprostone]]; NFE2L2 protein promotes the reaction [Dimethyl Fumarate inhibits the reaction [Lipopolysaccharides results in increased abundance of Nitrites]] Dimethyl Fumarate results in increased expression of NFE2L2 protein Dimethyl Fumarate affects the localization of NFE2L2 protein NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of FTH1 mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of FTL mRNA]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of FTL protein]; NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of HMOX1 protein] |
CTD |
PMID:23942037 PMID:27277809 PMID:28289076 PMID:28790194 PMID:29950142 |
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NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
increases activity multiple interactions increases expression |
ISO EXP |
Dimethyl Fumarate results in increased activity of NQO1 protein NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of NQO1 mRNA] Dimethyl Fumarate results in increased expression of NQO1 mRNA; Dimethyl Fumarate results in increased expression of NQO1 protein [Dimethyl Fumarate results in increased activity of NQO1 protein] which results in increased susceptibility to Mitomycin; [Dimethyl Fumarate results in increased activity of NQO1 protein] which results in increased susceptibility to Streptonigrin |
CTD |
PMID:15655414 PMID:16045903 PMID:27277809 PMID:28790194 PMID:30248482 |
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NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
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G |
Pdgfb |
platelet derived growth factor subunit B |
multiple interactions |
ISO |
[Dimethyl Fumarate results in increased expression of HMOX1 protein] which results in decreased susceptibility to PDGFB protein |
CTD |
PMID:20961405 |
|
NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
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G |
Polg2 |
DNA polymerase gamma 2, accessory subunit |
increases expression multiple interactions |
ISO |
Dimethyl Fumarate results in increased expression of POLG2 mRNA NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of POLG2 mRNA] |
CTD |
PMID:27277809 |
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NCBI chr10:94,968,836...94,979,259
Ensembl chr10:94,968,836...94,979,259
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G |
Polrmt |
RNA polymerase mitochondrial |
increases expression multiple interactions |
ISO |
Dimethyl Fumarate results in increased expression of POLRMT mRNA NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of POLRMT mRNA] |
CTD |
PMID:27277809 |
|
NCBI chr 7:12,840,907...12,851,153
Ensembl chr 7:12,840,938...12,851,153
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
Dimethyl Fumarate binds to and affects the localization of and results in decreased activity of RELA protein; Dimethyl Fumarate inhibits the reaction [TNF protein promotes the reaction [RELA protein binds to CCL2 promoter]]; Dimethyl Fumarate inhibits the reaction [TNF protein promotes the reaction [RELA protein binds to ICAM1 promoter]]; Dimethyl Fumarate inhibits the reaction [TNF protein results in increased activity of RELA protein] |
CTD |
PMID:26683377 |
|
NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
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G |
Sqstm1 |
sequestosome 1 |
increases expression multiple interactions |
ISO |
Dimethyl Fumarate results in increased expression of SQSTM1 protein NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of SQSTM1 protein] |
CTD |
PMID:29950142 |
|
NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
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G |
Ssbp1 |
single stranded DNA binding protein 1 |
increases expression multiple interactions |
ISO |
Dimethyl Fumarate results in increased expression of SSBP1 mRNA NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of SSBP1 mRNA] |
CTD |
PMID:27277809 |
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NCBI chr 4:68,634,844...68,645,112
Ensembl chr 4:68,634,929...68,645,172
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G |
Tfam |
transcription factor A, mitochondrial |
increases expression multiple interactions |
ISO |
Dimethyl Fumarate results in increased expression of TFAM mRNA NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of TFAM mRNA] |
CTD |
PMID:27277809 |
|
NCBI chr20:18,594,057...18,606,106
Ensembl chr20:18,594,037...18,606,151
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G |
Tfb1m |
transcription factor B1, mitochondrial |
multiple interactions increases expression |
ISO |
NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of TFB1M mRNA] |
CTD |
PMID:27277809 |
|
NCBI chr 1:44,433,116...44,474,674
Ensembl chr 1:44,433,116...44,474,674
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G |
Tfb2m |
transcription factor B2, mitochondrial |
increases expression multiple interactions |
ISO |
Dimethyl Fumarate results in increased expression of TFB2M mRNA NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of TFB2M mRNA] |
CTD |
PMID:27277809 |
|
NCBI chr13:97,820,493...97,838,275
Ensembl chr13:97,820,493...97,838,228 Ensembl chr13:97,820,493...97,838,228
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
EXP |
Dimethyl Fumarate inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein] |
CTD |
PMID:30703375 |
|
NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
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G |
Tnf |
tumor necrosis factor |
multiple interactions decreases expression |
ISO |
Acetylcysteine inhibits the reaction [Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; Acetylcysteine inhibits the reaction [Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]]; Acetylcysteine inhibits the reaction [Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of TNF mRNA]]; Dimethyl Fumarate inhibits the reaction [IKBKB protein results in increased expression of TNF mRNA]; Dimethyl Fumarate inhibits the reaction [TNF protein promotes the reaction [RELA protein binds to CCL2 promoter]]; Dimethyl Fumarate inhibits the reaction [TNF protein promotes the reaction [RELA protein binds to ICAM1 promoter]]; Dimethyl Fumarate inhibits the reaction [TNF protein results in increased activity of RELA protein]; Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of TNF mRNA] Dimethyl Fumarate inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of TNF mRNA] Dimethyl Fumarate results in decreased expression of TNF mRNA |
CTD |
PMID:26683377 PMID:27277809 |
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NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000 Ensembl chr20:5,189,390...5,192,000
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G |
Tnfsf11 |
TNF superfamily member 11 |
multiple interactions |
ISO |
Dimethyl Fumarate inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of ATP6V0D2 mRNA]; Dimethyl Fumarate inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of CTSK mRNA] |
CTD |
PMID:30742845 |
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NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
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G |
Twnk |
twinkle mtDNA helicase |
multiple interactions increases expression |
ISO |
NFE2L2 protein affects the reaction [Dimethyl Fumarate results in increased expression of TWNK mRNA] |
CTD |
PMID:27277809 |
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NCBI chr 1:264,756,060...264,762,892
Ensembl chr 1:264,756,499...264,762,892
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