CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: Vinpocetine
Accession: CHEBI:32297
browse the term
Synonyms: related_synonym: Formula=C22H26N2O2; InChI=1S/C22H26N2O2/c1-3-22-11-7-12-23-13-10-16-15-8-5-6-9-17(15)24(19(16)20(22)23)18(14-22)21(25)26-4-2/h5-6,8-9,14,20H,3-4,7,10-13H2,1-2H3/t20-,22+/m1/s1; InChIKey=DDNCQMVWWZOMLN-IRLDBZIGSA-N; SMILES=CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4C(=C2)C(=O)OCC; apovincaminic acid ethyl ester; bravinton; cavinton; ceractin; ethyl apovincaminate; ethyl apovincaminate tartrate; vinporal
alt_id: CHEBI:92929
xref: CAS:42971-09-5; Drug_Central:2828; KEGG:D01371; LINCS:LSM-3178
xref_mesh: MESH:C013983
G
Agt
angiotensinogen
multiple interactions
EXP
vinpocetine inhibits the reaction [AGT protein inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]]
CTD
PMID:11696475
NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
G
Il1b
interleukin 1 beta
multiple interactions
ISO
vinpocetine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL1B protein]
CTD
PMID:25980587
NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
G
Il33
interleukin 33
multiple interactions
ISO
vinpocetine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL33 protein]
CTD
PMID:25980587
NCBI chr 1:248,112,611...248,147,030
Ensembl chr 1:248,132,090...248,147,029
G
Kcnh2
potassium voltage-gated channel subfamily H member 2
multiple interactions decreases activity
ISO
vinpocetine inhibits the reaction [KCNH2 protein results in increased transport of Thallium] vinpocetine results in decreased activity of KCNH2 protein
CTD
PMID:17146843 PMID:19583963
NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
G
Mpo
myeloperoxidase
multiple interactions
ISO
vinpocetine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of MPO protein]
CTD
PMID:25980587
NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
G
Nppa
natriuretic peptide A
multiple interactions
EXP
vinpocetine inhibits the reaction [AGT protein inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]]
CTD
PMID:11696475
NCBI chr 5:164,808,407...164,809,716
Ensembl chr 5:164,808,323...164,809,705
G
Pde7b
phosphodiesterase 7B
multiple interactions
ISO
vinpocetine inhibits the reaction [PDE7B protein results in increased hydrolysis of Cyclic AMP]
CTD
PMID:10814504
NCBI chr 1:15,889,845...16,203,909
Ensembl chr 1:15,893,533...16,203,909
G
Tnf
tumor necrosis factor
multiple interactions
ISO
vinpocetine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]
CTD
PMID:25980587
NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
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