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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:phenformin
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Accession:CHEBI:8064 term browser browse the term
Definition:A member of the class of biguanides that is biguanide in which one of the terminal nitrogen atoms is substituted by a 2-phenylethyl group. It was used as an anti-diabetic drug but was later withdrawn from the market due to potential risk of lactic acidosis.
Synonyms:exact_synonym: N-(2-phenylethyl)imidodicarbonimidic diamide
 related_synonym: DBI;   Formula=C10H15N5;   InChI=1S/C10H15N5/c11-9(12)15-10(13)14-7-6-8-4-2-1-3-5-8/h1-5H,6-7H2,(H6,11,12,13,14,15);   InChIKey=ICFJFFQQTFMIBG-UHFFFAOYSA-N;   SMILES=NC(=N)NC(=N)NCCC1=CC=CC=C1;   fenformina;   phenformine;   phenforminum
 xref: CAS:114-86-3;   DrugBank:DB00914;   Drug_Central:2126;   HMDB:HMDB0015050;   KEGG:C07673;   KEGG:D08351;   LINCS:LSM-2233
 xref_mesh: MESH:D010629
 xref: PDBeChem:8CV;   PMID:16567854;   PMID:18239244;   PMID:20188727;   PMID:21084729;   PMID:22036620;   PMID:22361631;   PMID:23322141;   PMID:23475884;   PMID:23548904;   PMID:23612073;   PMID:28766937;   PMID:7390164;   Patent:US2961377;   Patent:US3057780;   Patent:WO2010114805;   Reaxys:1977317;   Wikipedia:Phenformin



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phenformin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression EXP Phenformin results in decreased expression of A2M mRNA CTD PMID:31324951 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 increases expression EXP Phenformin results in increased expression of ABCB4 mRNA CTD PMID:31324951 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression EXP Phenformin results in increased expression of ABCC3 mRNA CTD PMID:31324951 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcd2 ATP binding cassette subfamily D member 2 increases expression EXP Phenformin results in increased expression of ABCD2 mRNA CTD PMID:31324951 NCBI chr 7:122,263,034...122,311,642
Ensembl chr 7:122,263,032...122,311,642
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 decreases expression EXP Phenformin results in decreased expression of ABCG2 mRNA CTD PMID:31324951 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression EXP Phenformin results in increased expression of ABCG5 mRNA CTD PMID:31324951 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression EXP Phenformin results in increased expression of ABCG8 mRNA CTD PMID:31324951 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
JBrowse link
G Abra actin-binding Rho activating protein decreases expression EXP Phenformin results in decreased expression of ABRA mRNA CTD PMID:31324951 NCBI chr 7:72,970,187...72,974,255
Ensembl chr 7:72,970,186...72,974,255
JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases expression EXP Phenformin results in decreased expression of ACACA mRNA CTD PMID:31324951 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Ackr3 atypical chemokine receptor 3 decreases expression EXP Phenformin results in decreased expression of ACKR3 mRNA CTD PMID:31324951 NCBI chr 9:90,799,682...90,811,246
Ensembl chr 9:90,799,686...90,811,237
JBrowse link
G Acly ATP citrate lyase decreases expression EXP Phenformin results in decreased expression of ACLY mRNA CTD PMID:31324951 NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
JBrowse link
G Acmsd aminocarboxymuconate semialdehyde decarboxylase increases expression EXP Phenformin results in increased expression of ACMSD mRNA CTD PMID:31324951 NCBI chr13:39,200,486...39,244,337
Ensembl chr13:39,200,314...39,245,209
JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression EXP Phenformin results in decreased expression of ACSL3 mRNA CTD PMID:31324951 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627
JBrowse link
G Actg1 actin, gamma 1 decreases expression EXP Phenformin results in decreased expression of ACTG1 mRNA CTD PMID:31324951 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 decreases expression EXP Phenformin results in decreased expression of ADAMTS1 mRNA CTD PMID:31324951 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide increases expression EXP Phenformin results in increased expression of ADH4 mRNA CTD PMID:31324951 NCBI chr 2:226,948,717...226,966,747 JBrowse link
G Adh6 alcohol dehydrogenase 6 (class V) increases expression EXP Phenformin results in increased expression of ADH6 mRNA CTD PMID:31324951 NCBI chr 2:226,903,208...226,934,564
Ensembl chr 2:226,903,250...226,934,534
JBrowse link
G Afmid arylformamidase decreases expression EXP Phenformin results in decreased expression of AFMID mRNA CTD PMID:31324951 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718
JBrowse link
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase increases expression EXP Phenformin results in increased expression of AGXT mRNA CTD PMID:31324951 NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO Phenformin results in increased phosphorylation of AKT1 protein CTD PMID:19901985 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 decreases expression EXP Phenformin results in decreased expression of ALAS2 mRNA CTD PMID:31324951 NCBI chr  X:19,463,146...19,486,526
Ensembl chr  X:19,463,171...19,486,519
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP Phenformin results in increased expression of ALDH1A1 mRNA CTD PMID:31324951 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Alox15 arachidonate 15-lipoxygenase decreases expression EXP Phenformin results in decreased expression of ALOX15 mRNA CTD PMID:31324951 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874
JBrowse link
G Amacr alpha-methylacyl-CoA racemase increases expression EXP Phenformin results in increased expression of AMACR mRNA CTD PMID:31324951 NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255
JBrowse link
G Amdhd1 amidohydrolase domain containing 1 increases expression EXP Phenformin results in increased expression of AMDHD1 mRNA CTD PMID:31324951 NCBI chr 7:28,043,923...28,059,156
Ensembl chr 7:28,043,716...28,059,156
JBrowse link
G Angptl4 angiopoietin-like 4 affects expression EXP Phenformin affects the expression of ANGPTL4 mRNA CTD PMID:31324951 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Angptl8 angiopoietin-like 8 decreases expression EXP Phenformin results in decreased expression of ANGPTL8 mRNA CTD PMID:31324951 NCBI chr 8:20,376,462...20,378,488
Ensembl chr 8:20,376,462...20,378,490
JBrowse link
G Ankh ANKH inorganic pyrophosphate transport regulator decreases expression EXP Phenformin results in decreased expression of ANKH mRNA CTD PMID:31324951 NCBI chr 2:78,153,027...78,280,181
Ensembl chr 2:78,153,026...78,280,187
JBrowse link
G Anlnl1 anillin, actin binding protein-like 1 decreases expression EXP Phenformin results in decreased expression of ANLNL1 mRNA CTD PMID:31324951 NCBI chr17:57,985,340...57,995,824
Ensembl chr17:57,986,511...57,989,997
JBrowse link
G Ano5 anoctamin 5 decreases expression EXP Phenformin results in decreased expression of ANO5 mRNA CTD PMID:31324951 NCBI chr 1:101,086,490...101,187,547
Ensembl chr 1:101,087,341...101,187,555
JBrowse link
G Apcdd1 APC down-regulated 1 increases expression EXP Phenformin results in increased expression of APCDD1 mRNA CTD PMID:31324951 NCBI chr18:56,385,398...56,416,065
Ensembl chr18:56,385,264...56,416,070
JBrowse link
G Aph1b aph-1 homolog B, gamma secretase subunit decreases expression EXP Phenformin results in decreased expression of APH1B mRNA CTD PMID:31324951 NCBI chr 8:67,429,198...67,454,735
Ensembl chr 8:67,429,198...67,450,243
JBrowse link
G Aplnr apelin receptor increases expression EXP Phenformin results in increased expression of APLNR mRNA CTD PMID:31324951 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050
JBrowse link
G Apoa4 apolipoprotein A4 decreases expression EXP Phenformin results in decreased expression of APOA4 mRNA CTD PMID:31324951 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoc4 apolipoprotein C4 increases expression EXP Phenformin results in increased expression of APOC4 mRNA CTD PMID:31324951 NCBI chr 1:79,335,745...79,339,942
Ensembl chr 1:79,335,745...79,339,981
JBrowse link
G Apof apolipoprotein F increases expression EXP Phenformin results in increased expression of APOF mRNA CTD PMID:31324951 NCBI chr 7:700,688...702,130
Ensembl chr 7:700,762...701,946
JBrowse link
G Apold1 apolipoprotein L domain containing 1 decreases expression EXP Phenformin results in decreased expression of APOLD1 mRNA CTD PMID:31324951 NCBI chr 4:167,768,437...167,825,706
Ensembl chr 4:167,818,271...167,825,706
JBrowse link
G Aqp7 aquaporin 7 increases expression EXP Phenformin results in increased expression of AQP7 mRNA CTD PMID:31324951 NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642
JBrowse link
G Aqp9 aquaporin 9 increases expression EXP Phenformin results in increased expression of AQP9 mRNA CTD PMID:31324951 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395
JBrowse link
G Ar androgen receptor decreases expression EXP Phenformin results in decreased expression of AR mRNA CTD PMID:31324951 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arhgap11a Rho GTPase activating protein 11A decreases expression EXP Phenformin results in decreased expression of ARHGAP11A mRNA CTD PMID:31324951 NCBI chr 3:100,590,865...100,607,146
Ensembl chr 3:100,590,865...100,607,559
JBrowse link
G Arrdc4 arrestin domain containing 4 increases expression EXP Phenformin results in increased expression of ARRDC4 mRNA CTD PMID:31324951 NCBI chr 1:122,369,355...122,383,351
Ensembl chr 1:122,369,360...122,383,290
JBrowse link
G Asl argininosuccinate lyase increases expression EXP Phenformin results in increased expression of ASL mRNA CTD PMID:31324951 NCBI chr12:26,659,664...26,677,136
Ensembl chr12:26,659,565...26,679,662
JBrowse link
G Aspm assembly factor for spindle microtubules decreases expression EXP Phenformin results in decreased expression of ASPM mRNA CTD PMID:31324951 NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755
JBrowse link
G Aspn asporin decreases expression EXP Phenformin results in decreased expression of ASPN mRNA CTD PMID:31324951 NCBI chr17:15,079,910...15,104,369
Ensembl chr17:15,080,639...15,104,041
JBrowse link
G Atf3 activating transcription factor 3 decreases expression EXP Phenformin results in decreased expression of ATF3 mRNA CTD PMID:31324951 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Aurkb aurora kinase B decreases expression EXP Phenformin results in decreased expression of AURKB mRNA CTD PMID:31324951 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Bex1 brain expressed, X-linked 1 increases expression EXP Phenformin results in increased expression of BEX1 mRNA CTD PMID:31324951 NCBI chr  X:99,219,015...99,220,411 JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 decreases expression EXP Phenformin results in decreased expression of BHLHE40 mRNA CTD PMID:31324951 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
JBrowse link
G Btg2 BTG anti-proliferation factor 2 decreases expression EXP Phenformin results in decreased expression of BTG2 mRNA CTD PMID:31324951 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression EXP Phenformin results in decreased expression of BUB1 mRNA CTD PMID:31324951 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G Ca5a carbonic anhydrase 5A increases expression EXP Phenformin results in increased expression of CAR5A mRNA CTD PMID:31324951 NCBI chr19:49,973,092...50,002,948
Ensembl chr19:49,973,107...50,002,906
JBrowse link
G Ca5b carbonic anhydrase 5B decreases expression EXP Phenformin results in decreased expression of CAR5B mRNA CTD PMID:31324951 NCBI chr  X:30,474,697...30,534,797
Ensembl chr  X:30,474,784...30,533,837
JBrowse link
G Ccdc141 coiled-coil domain containing 141 decreases expression EXP Phenformin results in decreased expression of CCDC141 mRNA CTD PMID:31324951 NCBI chr 3:61,948,614...62,109,968
Ensembl chr 3:61,948,646...62,110,079
JBrowse link
G Ccdc38 coiled-coil domain containing 38 increases expression EXP Phenformin results in increased expression of CCDC38 mRNA CTD PMID:31324951 NCBI chr 7:28,055,883...28,129,938
Ensembl chr 7:28,059,798...28,130,441
JBrowse link
G Ccdc77 coiled-coil domain containing 77 increases expression EXP Phenformin results in increased expression of CCDC77 mRNA CTD PMID:31324951 NCBI chr 4:153,534,184...153,566,059
Ensembl chr 4:153,534,187...153,566,545
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression EXP Phenformin results in decreased expression of CCL2 mRNA CTD PMID:31324951 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression EXP Phenformin results in decreased expression of CCN2 mRNA CTD PMID:31324951 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccna2 cyclin A2 decreases expression EXP Phenformin results in decreased expression of CCNA2 mRNA CTD PMID:31324951 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression EXP Phenformin results in decreased expression of CCNB1 mRNA CTD PMID:31324951 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 affects expression EXP Phenformin affects the expression of CCNB2 mRNA CTD PMID:31324951 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Ccnd1 cyclin D1 increases expression EXP Phenformin results in increased expression of CCND1 mRNA CTD PMID:31324951 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne2 cyclin E2 decreases expression EXP Phenformin results in decreased expression of CCNE2 mRNA CTD PMID:31324951 NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632
JBrowse link
G Cd226 CD226 molecule decreases expression EXP Phenformin results in decreased expression of CD226 mRNA CTD PMID:31324951 NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051
JBrowse link
G Cd274 CD274 molecule increases expression EXP Phenformin results in increased expression of CD274 mRNA CTD PMID:31324951 NCBI chr 1:227,116,627...227,137,379
Ensembl chr 1:227,116,649...227,134,450
JBrowse link
G Cd5l Cd5 molecule-like increases expression EXP Phenformin results in increased expression of CD5L mRNA CTD PMID:31324951 NCBI chr 2:172,791,007...172,802,018 JBrowse link
G Cd63 Cd63 molecule increases expression EXP Phenformin results in increased expression of CD63 mRNA CTD PMID:31324951 NCBI chr 7:1,325,108...1,340,447
Ensembl chr 7:1,325,103...1,399,178
JBrowse link
G Cd74 CD74 molecule increases expression EXP Phenformin results in increased expression of CD74 mRNA CTD PMID:31324951 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cdc20 cell division cycle 20 decreases expression EXP Phenformin results in decreased expression of CDC20 mRNA CTD PMID:31324951 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression EXP Phenformin results in decreased expression of CDK1 mRNA CTD PMID:31324951 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
decreases expression
ISO
EXP
Phenformin results in increased expression of CDKN1A protein
Phenformin results in decreased expression of CDKN1A mRNA
CTD PMID:14623034 PMID:31324951 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression EXP Phenformin results in decreased expression of CDKN3 mRNA CTD PMID:31324951 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Cemip2 cell migration inducing hyaluronidase 2 decreases expression EXP Phenformin results in decreased expression of TMEM2 mRNA CTD PMID:31324951 NCBI chr 1:219,330,295...219,407,760
Ensembl chr 1:219,337,985...219,407,760
JBrowse link
G Cenpe centromere protein E decreases expression EXP Phenformin results in decreased expression of CENPE mRNA CTD PMID:31324951 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
JBrowse link
G Cenpf centromere protein F decreases expression EXP Phenformin results in decreased expression of CENPF mRNA CTD PMID:31324951 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
JBrowse link
G Ces2c carboxylesterase 2C increases expression EXP Phenformin results in increased expression of CES2C mRNA CTD PMID:31324951 NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790
JBrowse link
G Ces4a carboxylesterase 4A decreases expression EXP Phenformin results in decreased expression of CES4A mRNA CTD PMID:31324951 NCBI chr19:33,011,731...33,030,119
Ensembl chr19:33,011,731...33,029,545
JBrowse link
G Chka choline kinase alpha decreases expression EXP Phenformin results in decreased expression of CHKA mRNA CTD PMID:31324951 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
JBrowse link
G Cish cytokine inducible SH2-containing protein decreases expression EXP Phenformin results in decreased expression of CISH mRNA CTD PMID:31324951 NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250
JBrowse link
G Ckap2 cytoskeleton associated protein 2 decreases expression EXP Phenformin results in decreased expression of CKAP2 mRNA CTD PMID:31324951 NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression EXP Phenformin results in decreased expression of CKS2 mRNA CTD PMID:31324951 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Clec1a C-type lectin domain family 1, member A decreases expression EXP Phenformin results in decreased expression of CLEC1A mRNA CTD PMID:31324951 NCBI chr 4:162,875,360...162,902,571
Ensembl chr 4:162,877,346...162,901,247
JBrowse link
G Clec1b C-type lectin domain family 1, member B decreases expression EXP Phenformin results in decreased expression of CLEC1B mRNA CTD PMID:31324951 NCBI chr 4:162,847,978...162,856,291
Ensembl chr 4:162,848,010...162,856,291
JBrowse link
G Cpne8 copine 8 increases expression EXP Phenformin results in increased expression of CPNE8 mRNA CTD PMID:31324951 NCBI chr 7:121,615,293...121,789,507
Ensembl chr 7:121,615,294...121,790,377
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP Phenformin results in increased expression of CPT1A mRNA CTD PMID:31324951 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Crat carnitine O-acetyltransferase increases expression EXP Phenformin results in increased expression of CRAT mRNA CTD PMID:31324951 NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255
JBrowse link
G Crot carnitine O-octanoyltransferase increases expression EXP Phenformin results in increased expression of CROT mRNA CTD PMID:31324951 NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109
JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression EXP Phenformin results in decreased expression of CRY1 mRNA CTD PMID:31324951 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
JBrowse link
G Cryl1 crystallin, lambda 1 increases expression EXP Phenformin results in increased expression of CRYL1 mRNA CTD PMID:31324951 NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997
JBrowse link
G Csad cysteine sulfinic acid decarboxylase decreases expression EXP Phenformin results in decreased expression of CSAD mRNA CTD PMID:31324951 NCBI chr 7:133,308,571...133,337,914
Ensembl chr 7:133,308,574...133,337,615
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 decreases expression EXP Phenformin results in decreased expression of CSRP1 mRNA CTD PMID:31324951 NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 decreases expression EXP Phenformin results in decreased expression of CXCL1 mRNA CTD PMID:31324951 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression EXP Phenformin results in decreased expression of CXCL10 mRNA CTD PMID:31324951 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression EXP Phenformin results in increased expression of CXCR4 mRNA CTD PMID:31324951 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP Phenformin results in decreased expression of CYP17A1 mRNA CTD PMID:31324951 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 increases expression EXP Phenformin results in increased expression of CYP2B1 mRNA CTD PMID:31324951 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 decreases expression EXP Phenformin results in decreased expression of CYP2C12 mRNA CTD PMID:31324951 NCBI chr 1:238,699,859...238,757,011
Ensembl chr 1:238,699,854...238,757,019
JBrowse link
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 increases expression EXP Phenformin results in increased expression of CYP2C24 mRNA CTD PMID:31324951 NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP Phenformin results in increased expression of CYP2E1 mRNA CTD PMID:31324951 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 increases expression EXP Phenformin results in increased expression of CYP3A18 mRNA CTD PMID:31324951 NCBI chr12:8,880,528...8,930,382
Ensembl chr12:8,880,528...8,930,381
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP Phenformin results in increased expression of CYP4A1 mRNA CTD PMID:31324951 NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
JBrowse link
G Cyp4a2 cytochrome P450, family 4, subfamily a, polypeptide 2 increases expression EXP Phenformin results in increased expression of CYP4A2 mRNA CTD PMID:31324951 NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression EXP Phenformin results in decreased expression of CYP7A1 mRNA CTD PMID:31324951 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 increases expression EXP Phenformin results in increased expression of CYP8B1 mRNA CTD PMID:31324951 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor increases expression EXP Phenformin results in increased expression of DBP mRNA CTD PMID:31324951 NCBI chr 1:96,175,796...96,180,745
Ensembl chr 1:96,175,440...96,180,745
JBrowse link
G Dcn decorin decreases expression EXP Phenformin results in decreased expression of DCN mRNA CTD PMID:31324951 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Ddhd1 DDHD domain containing 1 increases expression EXP Phenformin results in increased expression of DDHD1 mRNA CTD PMID:31324951 NCBI chr15:18,824,389...18,891,036
Ensembl chr15:18,824,394...18,890,952
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 decreases expression EXP Phenformin results in decreased expression of DDIT4 mRNA CTD PMID:31324951 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 increases expression EXP Phenformin results in increased expression of DECR1 mRNA CTD PMID:31324951 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
JBrowse link
G Depdc1 DEP domain containing 1 decreases expression EXP Phenformin results in decreased expression of DEPDC1 mRNA CTD PMID:31324951 NCBI chr 2:248,684,508...248,717,951
Ensembl chr 2:248,684,523...248,717,951
JBrowse link
G Diaph3 diaphanous-related formin 3 decreases expression EXP Phenformin results in decreased expression of DIAPH3 mRNA CTD PMID:31324951 NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975
JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases expression EXP Phenformin results in decreased expression of DIO1 mRNA CTD PMID:31324951 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970
JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 increases expression EXP Phenformin results in increased expression of DMBT1 mRNA CTD PMID:31324951 NCBI chr 1:185,617,469...185,696,476 JBrowse link
G Dmxl2 Dmx-like 2 decreases expression EXP Phenformin results in decreased expression of DMXL2 mRNA CTD PMID:31324951 NCBI chr 8:54,741,164...54,884,948
Ensembl chr 8:54,741,160...54,885,161
JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression EXP Phenformin results in decreased expression of DUSP1 mRNA CTD PMID:31324951 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Ech1 enoyl-CoA hydratase 1 increases expression EXP Phenformin results in increased expression of ECH1 mRNA CTD PMID:31324951 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 increases expression EXP Phenformin results in increased expression of ECI1 mRNA CTD PMID:31324951 NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
JBrowse link
G Ect2 epithelial cell transforming 2 decreases expression EXP Phenformin results in decreased expression of ECT2 mRNA CTD PMID:31324951 NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 decreases expression EXP Phenformin results in decreased expression of EDEM1 mRNA CTD PMID:31324951 NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717
JBrowse link
G Edil3 EGF like repeats and discoidin domains 3 decreases expression EXP Phenformin results in decreased expression of EDIL3 mRNA CTD PMID:31324951 NCBI chr 2:19,890,396...20,405,028
Ensembl chr 2:19,890,373...20,405,008
JBrowse link
G Egr1 early growth response 1 decreases expression EXP Phenformin results in decreased expression of EGR1 mRNA CTD PMID:31324951 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 decreases expression EXP Phenformin results in decreased expression of ELL2 mRNA CTD PMID:31324951 NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781
JBrowse link
G Elovl2 ELOVL fatty acid elongase 2 increases expression EXP Phenformin results in increased expression of ELOVL2 mRNA CTD PMID:31324951 NCBI chr17:23,544,520...23,584,855
Ensembl chr17:23,544,568...23,584,848
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 decreases expression EXP Phenformin results in decreased expression of ELOVL6 mRNA CTD PMID:31324951 NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
JBrowse link
G Erich5 glutamate-rich 5 decreases expression EXP Phenformin results in decreased expression of ERICH5 mRNA CTD PMID:31324951 NCBI chr 7:65,655,829...65,682,221
Ensembl chr 7:65,657,204...65,680,207
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 decreases expression EXP Phenformin results in decreased expression of ERRFI1 mRNA CTD PMID:31324951 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 decreases expression EXP Phenformin results in decreased expression of ESCO2 mRNA CTD PMID:31324951 NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306
JBrowse link
G Esm1 endothelial cell-specific molecule 1 increases expression EXP Phenformin results in increased expression of ESM1 mRNA CTD PMID:31324951 NCBI chr 2:44,876,067...44,884,805
Ensembl chr 2:44,876,067...44,884,804
JBrowse link
G F2rl2 coagulation factor II (thrombin) receptor-like 2 decreases expression EXP Phenformin results in decreased expression of F2RL2 mRNA CTD PMID:31324951 NCBI chr 2:26,972,054...26,977,098
Ensembl chr 2:26,972,054...26,977,098
JBrowse link
G F3 coagulation factor III, tissue factor decreases expression EXP Phenformin results in decreased expression of F3 mRNA CTD PMID:31324951 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression EXP Phenformin results in decreased expression of FABP5 mRNA CTD PMID:31324951 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
JBrowse link
G Fam111a FAM111 trypsin like peptidase A decreases expression EXP Phenformin results in decreased expression of FAM111A mRNA CTD PMID:31324951 NCBI chr 1:209,640,865...209,656,551
Ensembl chr 1:209,640,953...209,656,547
JBrowse link
G Fam117b family with sequence similarity 117, member B increases expression EXP Phenformin results in increased expression of FAM117B mRNA CTD PMID:31324951 NCBI chr 9:61,340,291...61,418,531
Ensembl chr 9:61,340,249...61,408,483
JBrowse link
G Fam149a family with sequence similarity 149, member A decreases expression EXP Phenformin results in decreased expression of FAM149A mRNA CTD PMID:31324951 NCBI chr16:46,855,377...46,914,553
Ensembl chr16:46,854,635...46,912,066
JBrowse link
G Fam83d family with sequence similarity 83, member D decreases expression EXP Phenformin results in decreased expression of FAM83D mRNA CTD PMID:31324951 NCBI chr 3:147,421,941...147,441,211
Ensembl chr 3:147,421,908...147,441,192
JBrowse link
G Fasn fatty acid synthase decreases expression EXP Phenformin results in decreased expression of FASN mRNA CTD PMID:31324951 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 decreases expression EXP Phenformin results in decreased expression of FMO2 mRNA CTD PMID:31324951 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
JBrowse link
G Fmo5 flavin containing dimethylaniline monoxygenase 5 increases expression EXP Phenformin results in increased expression of FMO5 mRNA CTD PMID:31324951 NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit decreases expression EXP Phenformin results in decreased expression of FOS mRNA CTD PMID:31324951 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Foxa1 forkhead box A1 decreases expression EXP Phenformin results in decreased expression of FOXA1 mRNA CTD PMID:31324951 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
JBrowse link
G Foxa2 forkhead box A2 decreases expression EXP Phenformin results in decreased expression of FOXA2 mRNA CTD PMID:31324951 NCBI chr 3:135,470,123...135,474,326
Ensembl chr 3:135,470,131...135,474,326
JBrowse link
G Foxo3 forkhead box O3 decreases expression EXP Phenformin results in decreased expression of FOXO3 mRNA CTD PMID:31324951 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Fpr1 formyl peptide receptor 1 decreases expression EXP Phenformin results in decreased expression of FPR1 mRNA CTD PMID:31324951 NCBI chr 1:58,745,019...58,756,776
Ensembl chr 1:58,747,246...58,756,559
JBrowse link
G Fras1 Fraser extracellular matrix complex subunit 1 decreases expression EXP Phenformin results in decreased expression of FRAS1 mRNA CTD PMID:31324951 NCBI chr14:12,791,407...13,200,862
Ensembl chr14:12,793,599...13,200,726
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression EXP Phenformin results in decreased expression of G6PC1 mRNA CTD PMID:31324951 NCBI chr10:86,307,400...86,318,766 JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma decreases expression EXP Phenformin results in decreased expression of GADD45G mRNA CTD PMID:31324951 NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 decreases expression EXP Phenformin results in decreased expression of GBE1 mRNA CTD PMID:31324951 NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210
JBrowse link
G Gbp1 guanylate binding protein 1 increases expression EXP Phenformin results in increased expression of GBP1 mRNA CTD PMID:31324951 NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,517,398...231,529,600
JBrowse link
G Gck glucokinase decreases expression EXP Phenformin results in decreased expression of GCK mRNA CTD PMID:31324951 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
JBrowse link
G Gimd1 GIMAP family P-loop NTPase domain containing 1 decreases expression EXP Phenformin results in decreased expression of GIMD1 mRNA CTD PMID:31324951 NCBI chr 2:221,103,878...221,138,559
Ensembl chr 2:221,103,878...221,138,553
JBrowse link
G Gk glycerol kinase increases expression EXP Phenformin results in increased expression of GK mRNA CTD PMID:31324951 NCBI chr  X:50,162,089...50,238,707
Ensembl chr  X:50,163,123...50,238,631
JBrowse link
G Gnmt glycine N-methyltransferase increases expression EXP Phenformin results in increased expression of GNMT mRNA CTD PMID:31324951 NCBI chr 9:14,254,675...14,258,028
Ensembl chr 9:14,254,675...14,258,434
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 increases expression EXP Phenformin results in increased expression of GOT1 mRNA CTD PMID:31324951 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
JBrowse link
G Gp5 glycoprotein V (platelet) decreases expression EXP Phenformin results in decreased expression of GP5 mRNA CTD PMID:31324951 NCBI chr11:70,443,613...70,446,705
Ensembl chr11:70,443,613...70,446,705
JBrowse link
G Gpa33 glycoprotein A33 increases expression EXP Phenformin results in increased expression of GPA33 mRNA CTD PMID:31324951 NCBI chr13:78,381,141...78,414,765
Ensembl chr13:78,381,141...78,414,765
JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial increases expression EXP Phenformin results in increased expression of GPAM mRNA CTD PMID:31324951 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression EXP Phenformin results in increased expression of GPAT3 mRNA CTD PMID:31324951 NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 increases expression EXP Phenformin results in increased expression of GPD2 mRNA CTD PMID:31324951 NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901
JBrowse link
G Gpnmb glycoprotein nmb increases expression EXP Phenformin results in increased expression of GPNMB mRNA CTD PMID:31324951 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
JBrowse link
G Gprin3 GPRIN family member 3 decreases expression EXP Phenformin results in decreased expression of GPRIN3 mRNA CTD PMID:31324951 NCBI chr 4:88,563,708...88,657,603
Ensembl chr 4:88,563,607...88,657,429
JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression EXP Phenformin results in increased expression of GPT mRNA CTD PMID:31324951 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Gpx2-ps2 glutathione peroxidase 2, pseudogene 2 affects expression EXP Phenformin affects the expression of GPX2-PS2 mRNA CTD PMID:31324951 NCBI chr  X:59,444,660...59,445,203 JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression EXP Phenformin results in increased expression of GSTM2 mRNA CTD PMID:31324951 NCBI chr 2:195,624,015...195,628,774 JBrowse link
G Gstm4 glutathione S-transferase mu 4 increases expression EXP Phenformin results in increased expression of GSTM4 mRNA CTD PMID:31324951 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
JBrowse link
G Gstm7 glutathione S-transferase, mu 7 increases expression EXP Phenformin results in increased expression of GSTM7 mRNA CTD PMID:31324951 NCBI chr 2:195,566,701...195,572,149
Ensembl chr 2:195,566,701...195,572,203
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 increases expression EXP Phenformin results in increased expression of GSTZ1 mRNA CTD PMID:31324951 NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284
JBrowse link
G Gypa glycophorin A decreases expression EXP Phenformin results in decreased expression of GYPA mRNA CTD PMID:31324951 NCBI chr19:27,450,311...27,465,940 JBrowse link
G H2ac4 H2A clustered histone 4 decreases expression EXP Phenformin results in decreased expression of H2AC4 mRNA CTD PMID:31324951 NCBI chr17:42,799,953...42,800,345
Ensembl chr17:42,799,652...42,800,381
JBrowse link
G H2ax H2A.X variant histone decreases expression EXP Phenformin results in decreased expression of H2AX mRNA CTD PMID:31324951 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression EXP Phenformin results in decreased expression of HAMP mRNA CTD PMID:31324951 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
JBrowse link
G Hbb hemoglobin subunit beta decreases expression EXP Phenformin results in decreased expression of HBB-B1 mRNA CTD PMID:31324951 NCBI chr 1:158,250,421...158,251,832 JBrowse link
G Hbb-bs hemoglobin, beta adult s chain decreases expression EXP Phenformin results in decreased expression of HBB-BS mRNA CTD PMID:31324951 NCBI chr 1:158,218,356...158,219,722 JBrowse link
G Hhex hematopoietically expressed homeobox decreases expression EXP Phenformin results in decreased expression of HHEX mRNA CTD PMID:31324951 NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression ISO Phenformin results in increased expression of HIF1A protein CTD PMID:26768367 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hist1h2af histone cluster 1 H2A family member F decreases expression EXP Phenformin results in decreased expression of HIST1H2AF mRNA CTD PMID:31324951 NCBI chr17:41,379,404...41,379,796
Ensembl chr17:41,379,404...41,379,796
JBrowse link
G Hist1h2ail1 histone cluster 1 H2a family member I like 1 decreases expression EXP Phenformin results in decreased expression of HIST1H2AIL1 mRNA CTD PMID:31324951 NCBI chr17:41,568,666...41,569,076
Ensembl chr17:41,568,471...41,569,109
JBrowse link
G Hist2h3c2 histone cluster 2 H3 family member C2 decreases expression EXP Phenformin results in decreased expression of HIST2H3C2 mRNA CTD PMID:31324951 NCBI chr 2:183,837,311...183,837,721
Ensembl chr 2:183,837,303...183,837,752
JBrowse link
G Hlf HLF transcription factor, PAR bZIP family member decreases expression EXP Phenformin results in decreased expression of HLF mRNA CTD PMID:31324951 NCBI chr10:75,154,244...75,211,884
Ensembl chr10:75,154,507...75,211,935
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases expression EXP Phenformin results in decreased expression of HMGCR mRNA CTD PMID:31324951 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmmr hyaluronan-mediated motility receptor decreases expression EXP Phenformin results in decreased expression of HMMR mRNA CTD PMID:31324951 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 increases expression EXP Phenformin results in increased expression of HSD17B2 mRNA CTD PMID:31324951 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 decreases expression EXP Phenformin results in decreased expression of HSP90AA1 mRNA CTD PMID:31324951 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hspa4l heat shock protein family A (Hsp70) member 4 like decreases expression EXP Phenformin results in decreased expression of HSPA4L mRNA CTD PMID:31324951 NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084
JBrowse link
G Hykk hydroxylysine kinase increases expression EXP Phenformin results in increased expression of HYKK mRNA CTD PMID:31324951 NCBI chr 8:55,315,919...55,339,720
Ensembl chr 8:55,315,969...55,337,339
JBrowse link
G Ier2 immediate early response 2 decreases expression EXP Phenformin results in decreased expression of IER2 mRNA CTD PMID:31324951 NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211
JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 increases expression EXP Phenformin results in increased expression of IFITM3 mRNA CTD PMID:31324951 NCBI chr 1:196,111,026...196,112,135
Ensembl chr 1:196,111,043...196,112,203
JBrowse link
G Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 decreases expression EXP Phenformin results in decreased expression of IGF2BP3 mRNA CTD PMID:31324951 NCBI chr 4:78,060,494...78,195,007
Ensembl chr 4:78,060,494...78,194,865
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit decreases expression EXP Phenformin results in decreased expression of IGFALS mRNA CTD PMID:31324951 NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression EXP Phenformin results in increased expression of IGFBP2 mRNA CTD PMID:31324951 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 decreases expression EXP Phenformin results in decreased expression of IGFBP5 mRNA CTD PMID:31324951 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Il1r1 interleukin 1 receptor type 1 increases expression EXP Phenformin results in increased expression of IL1R1 mRNA CTD PMID:31324951 NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
JBrowse link
G Il33 interleukin 33 increases expression EXP Phenformin results in increased expression of IL33 mRNA CTD PMID:31324951 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373
JBrowse link
G Inha inhibin subunit alpha decreases expression EXP Phenformin results in decreased expression of INHA mRNA CTD PMID:31324951 NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248
JBrowse link
G Inhba inhibin subunit beta A decreases expression EXP Phenformin results in decreased expression of INHBA mRNA CTD PMID:31324951 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982
JBrowse link
G Inhbe inhibin subunit beta E increases expression EXP Phenformin results in increased expression of INHBE mRNA CTD PMID:31324951 NCBI chr 7:63,177,558...63,178,983
Ensembl chr 7:63,176,219...63,179,172
JBrowse link
G Inmt indolethylamine N-methyltransferase increases expression EXP Phenformin results in increased expression of INMT mRNA CTD PMID:31324951 NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493
JBrowse link
G Insig1 insulin induced gene 1 decreases expression EXP Phenformin results in decreased expression of INSIG1 mRNA CTD PMID:31324951 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Insig2 insulin induced gene 2 increases expression EXP Phenformin results in increased expression of INSIG2 mRNA CTD PMID:31324951 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 decreases expression EXP Phenformin results in decreased expression of IP6K2 mRNA CTD PMID:31324951 NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166
JBrowse link
G Irf2bp2 interferon regulatory factor 2 binding protein 2 decreases expression EXP Phenformin results in decreased expression of IRF2BP2 mRNA CTD PMID:31324951 NCBI chr19:54,559,409...54,564,714 JBrowse link
G Irf2bpl interferon regulatory factor 2 binding protein-like decreases expression EXP Phenformin results in decreased expression of IRF2BPL mRNA CTD PMID:31324951 NCBI chr 6:106,527,179...106,531,294
Ensembl chr 6:106,528,053...106,530,401
JBrowse link
G Irs2 insulin receptor substrate 2 decreases expression EXP Phenformin results in decreased expression of IRS2 mRNA CTD PMID:31324951 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression EXP Phenformin results in decreased expression of JUN mRNA CTD PMID:31324951 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit decreases expression EXP Phenformin results in decreased expression of JUNB mRNA CTD PMID:31324951 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 increases expression EXP Phenformin results in increased expression of KCNA2 mRNA CTD PMID:31324951 NCBI chr 2:194,704,555...194,718,387
Ensembl chr 2:194,704,639...194,718,400
JBrowse link
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 increases expression EXP Phenformin results in increased expression of KCNJ5 mRNA CTD PMID:31324951 NCBI chr 8:30,724,923...30,753,083
Ensembl chr 8:30,724,925...30,753,518
JBrowse link
G Kif11 kinesin family member 11 decreases expression EXP Phenformin results in decreased expression of KIF11 mRNA CTD PMID:31324951 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
JBrowse link
G Kif20a kinesin family member 20A decreases expression EXP Phenformin results in decreased expression of KIF20A mRNA CTD PMID:31324951 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
JBrowse link
G Kif20b kinesin family member 20B decreases expression EXP Phenformin results in decreased expression of KIF20B mRNA CTD PMID:31324951 NCBI chr 1:232,428,293...232,483,798
Ensembl chr 1:232,428,371...232,483,787
JBrowse link
G Kif23 kinesin family member 23 decreases expression EXP Phenformin results in decreased expression of KIF23 mRNA CTD PMID:31324951 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
JBrowse link
G Knl1 kinetochore scaffold 1 decreases expression EXP Phenformin results in decreased expression of KNL1 mRNA CTD PMID:31324951 NCBI chr 3:106,029,627...106,091,915
Ensembl chr 3:106,029,661...106,091,915
JBrowse link
G Krt18 keratin 18 increases expression EXP Phenformin results in increased expression of KRT18 mRNA CTD PMID:31324951 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
JBrowse link
G Lbp lipopolysaccharide binding protein increases expression EXP Phenformin results in increased expression of LBP mRNA CTD PMID:31324951 NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586
JBrowse link
G Lepr leptin receptor increases response to substance EXP LEPR gene mutant form results in increased susceptibility to Phenformin CTD PMID:29743445 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Lgals5 galectin 5 decreases expression EXP Phenformin results in decreased expression of LGALS5 mRNA CTD PMID:31324951 NCBI chr10:63,853,949...63,857,198
Ensembl chr10:63,853,935...63,857,153
JBrowse link
G Lgsn lengsin, lens protein with glutamine synthetase domain decreases expression EXP Phenformin results in decreased expression of LGSN mRNA CTD PMID:31324951 NCBI chr 9:33,416,362...33,447,919
Ensembl chr 9:33,420,484...33,447,907
JBrowse link
G Lipo1 lipase, member O1 decreases expression EXP Phenformin results in decreased expression of LIPO1 mRNA CTD PMID:31324951 NCBI chr 1:231,311,828...231,328,805
Ensembl chr 1:231,311,315...231,325,187
JBrowse link
G Loxl4 lysyl oxidase-like 4 increases expression EXP Phenformin results in increased expression of LOXL4 mRNA CTD PMID:31324951 NCBI chr 1:241,396,183...241,416,385
Ensembl chr 1:241,397,983...241,416,322
JBrowse link
G Lpar6 lysophosphatidic acid receptor 6 increases expression EXP Phenformin results in increased expression of LPAR6 mRNA CTD PMID:31324951 NCBI chr15:48,416,548...48,418,357
Ensembl chr15:48,416,544...48,422,331
JBrowse link
G Lpin1 lipin 1 decreases expression EXP Phenformin results in decreased expression of LPIN1 mRNA CTD PMID:31324951 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Lum lumican decreases expression EXP Phenformin results in decreased expression of LUM mRNA CTD PMID:31324951 NCBI chr 7:32,358,990...32,365,794
Ensembl chr 7:32,358,614...32,365,793
JBrowse link
G Lurap1l leucine rich adaptor protein 1-like decreases expression EXP Phenformin results in decreased expression of LURAP1L mRNA CTD PMID:31324951 NCBI chr 5:95,362,005...95,409,439
Ensembl chr 5:95,362,005...95,409,438
JBrowse link
G Ly6c Ly6-C antigen increases expression EXP Phenformin results in increased expression of LY6C mRNA CTD PMID:31324951 NCBI chr 7:106,959,508...106,963,360
Ensembl chr 7:106,959,511...106,963,329
JBrowse link
G Lynx1 Ly6/neurotoxin 1 decreases expression EXP Phenformin results in decreased expression of LYNX1 mRNA CTD PMID:31324951 NCBI chr 7:106,632,800...106,638,003
Ensembl chr 7:106,632,797...106,638,023
JBrowse link
G Mastl microtubule associated serine/threonine kinase-like decreases expression EXP Phenformin results in decreased expression of MASTL mRNA CTD PMID:31324951 NCBI chr17:85,250,512...85,287,479
Ensembl chr17:85,251,997...85,287,353
JBrowse link
G Mbnl3 muscleblind-like splicing regulator 3 increases expression EXP Phenformin results in increased expression of MBNL3 mRNA CTD PMID:31324951 NCBI chr  X:130,641,942...130,737,179
Ensembl chr  X:130,648,538...130,737,056
JBrowse link
G Mest mesoderm specific transcript decreases expression EXP Phenformin results in decreased expression of MEST mRNA CTD PMID:31324951 NCBI chr 4:59,354,445...59,364,919
Ensembl chr 4:59,354,447...59,366,145
JBrowse link
G Mfap4 microfibril associated protein 4 decreases expression EXP Phenformin results in decreased expression of MFAP4 mRNA CTD PMID:31324951 NCBI chr10:46,167,158...46,170,176
Ensembl chr10:46,167,217...46,170,155
JBrowse link
G Mfsd2a major facilitator superfamily domain containing 2A decreases expression EXP Phenformin results in decreased expression of MFSD2A mRNA CTD PMID:31324951 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690
JBrowse link
G Mgat4b alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B decreases expression EXP Phenformin results in decreased expression of MGAT4B mRNA CTD PMID:31324951 NCBI chr10:34,548,918...34,559,229
Ensembl chr10:34,549,433...34,559,229
JBrowse link
G Mgp matrix Gla protein decreases expression EXP Phenformin results in decreased expression of MGP mRNA CTD PMID:31324951 NCBI chr 4:169,766,290...169,769,612
Ensembl chr 4:169,766,279...169,769,667
JBrowse link
G Mir15b microRNA 15b increases expression EXP Phenformin results in increased expression of MIR15B mRNA CTD PMID:31324951 NCBI chr 2:153,245,200...153,245,297
Ensembl chr 2:153,245,200...153,245,297
JBrowse link
G Mir29b2 microRNA 29b-2 increases expression EXP Phenformin results in increased expression of MIR29B2 mRNA CTD PMID:31324951 NCBI chr13:106,570,371...106,570,451
Ensembl chr13:106,570,367...106,570,456
JBrowse link
G Mirlet7c1 microRNA let-7c-1 increases expression EXP Phenformin results in increased expression of MIRLET7C-1 mRNA CTD PMID:31324951 NCBI chr11:16,201,163...16,201,256
Ensembl chr11:16,201,158...16,201,265
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression EXP Phenformin results in decreased expression of MKI67 mRNA CTD PMID:31324951 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 decreases expression EXP Phenformin results in decreased expression of MKNK2 mRNA CTD PMID:31324951 NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827
JBrowse link
G Mlxipl MLX interacting protein-like decreases expression EXP Phenformin results in decreased expression of MLXIPL mRNA CTD PMID:31324951 NCBI chr12:21,542,964...21,577,120
Ensembl chr12:21,543,576...21,577,112
JBrowse link
G Mst1r macrophage stimulating 1 receptor decreases expression EXP Phenformin results in decreased expression of MST1R mRNA CTD PMID:31324951 NCBI chr 8:108,596,100...108,611,389
Ensembl chr 8:108,597,299...108,612,455
JBrowse link
G Mt1 metallothionein 1 increases expression EXP Phenformin results in increased expression of MT1A mRNA; Phenformin results in increased expression of MT1F mRNA CTD PMID:31324951 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Mt2A metallothionein 2A increases expression EXP Phenformin results in increased expression of MT2A mRNA CTD PMID:31324951 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mtss1 MTSS I-BAR domain containing 1 decreases expression EXP Phenformin results in decreased expression of MTSS1 mRNA CTD PMID:31324951 NCBI chr 7:90,488,751...90,628,007
Ensembl chr 7:90,488,754...90,627,968
JBrowse link
G Mx2 MX dynamin like GTPase 2 increases expression EXP Phenformin results in increased expression of MX2 mRNA CTD PMID:31324951 NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression EXP Phenformin results in decreased expression of MYC mRNA CTD PMID:31324951 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myh7 myosin heavy chain 7 increases expression EXP Phenformin results in increased expression of MYH7 mRNA CTD PMID:31324951 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217
JBrowse link
G Myoc myocilin increases expression EXP Phenformin results in increased expression of MYOC mRNA CTD PMID:31324951 NCBI chr13:74,976,730...74,987,128
Ensembl chr13:74,976,730...74,987,127
JBrowse link
G Myom2 myomesin 2 increases expression EXP Phenformin results in increased expression of MYOM2 mRNA CTD PMID:31324951 NCBI chr16:74,520,148...74,592,658
Ensembl chr16:74,520,157...74,592,772
JBrowse link
G Ncapg non-SMC condensin I complex, subunit G decreases expression EXP Phenformin results in decreased expression of NCAPG mRNA CTD PMID:31324951 NCBI chr14:65,404,235...65,432,902
Ensembl chr14:65,404,163...65,432,902
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 increases expression EXP Phenformin results in increased expression of NCF1 mRNA CTD PMID:31324951 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
JBrowse link
G Ndc80 NDC80 kinetochore complex component decreases expression EXP Phenformin results in decreased expression of NDC80 mRNA CTD PMID:31324951 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases activity ISO Phenformin results in increased activity of NFE2L2 protein CTD PMID:30114225 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression EXP Phenformin results in decreased expression of NFKBIA mRNA CTD PMID:31324951 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Ngef neuronal guanine nucleotide exchange factor decreases expression EXP Phenformin results in decreased expression of NGEF mRNA CTD PMID:31324951 NCBI chr 9:88,146,956...88,244,454
Ensembl chr 9:88,146,956...88,244,914
JBrowse link
G Noct nocturnin decreases expression EXP Phenformin results in decreased expression of NOCT mRNA CTD PMID:31324951 NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400
JBrowse link
G Nppa natriuretic peptide A increases expression EXP Phenformin results in increased expression of NPPA mRNA CTD PMID:31324951 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Npr3 natriuretic peptide receptor 3 increases expression EXP Phenformin results in increased expression of NPR3 mRNA CTD PMID:31324951 NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955
JBrowse link
G Npy neuropeptide Y affects expression EXP Phenformin affects the expression of NPY mRNA CTD PMID:31324951 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP Phenformin results in increased expression of NQO1 mRNA CTD PMID:31324951 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression EXP Phenformin results in increased expression of NR1D1 mRNA CTD PMID:31324951 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Nr1d2 nuclear receptor subfamily 1, group D, member 2 increases expression EXP Phenformin results in increased expression of NR1D2 mRNA CTD PMID:31324951 NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 decreases expression EXP Phenformin results in decreased expression of NR4A1 mRNA CTD PMID:31324951 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 decreases expression EXP Phenformin results in decreased expression of NR4A2 mRNA CTD PMID:31324951 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 decreases expression EXP Phenformin results in decreased expression of NR4A3 mRNA CTD PMID:31324951 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex decreases expression EXP Phenformin results in decreased expression of NUF2 mRNA CTD PMID:31324951 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 decreases expression EXP Phenformin results in decreased expression of NUSAP1 mRNA CTD PMID:31324951 NCBI chr 3:106,603,273...106,633,624
Ensembl chr 3:106,603,289...106,633,624
JBrowse link
G Oaf out at first homolog increases expression EXP Phenformin results in increased expression of OAF mRNA CTD PMID:31324951 NCBI chr 8:43,594,362...43,612,334
Ensembl chr 8:43,594,363...43,612,334
JBrowse link
G Oat ornithine aminotransferase increases expression EXP Phenformin results in increased expression of OAT mRNA CTD PMID:31324951 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
JBrowse link
G Olr906 olfactory receptor 906 increases expression EXP Phenformin results in increased expression of OLR906 mRNA CTD PMID:31324951 NCBI chr 7:1,821,264...1,822,202
Ensembl chr 7:1,821,264...1,822,202
JBrowse link
G Omd osteomodulin decreases expression EXP Phenformin results in decreased expression of OMD mRNA CTD PMID:31324951 NCBI chr17:15,060,217...15,068,441
Ensembl chr17:15,060,217...15,068,441
JBrowse link
G Opcml opioid binding protein/cell adhesion molecule-like decreases expression EXP Phenformin results in decreased expression of OPCML mRNA CTD PMID:31324951 NCBI chr 8:26,788,988...27,304,551
Ensembl chr 8:26,192,841...27,300,620
JBrowse link
G Osbpl3 oxysterol binding protein-like 3 decreases expression EXP Phenformin results in decreased expression of OSBPL3 mRNA CTD PMID:31324951 NCBI chr 4:79,346,583...79,523,523
Ensembl chr 4:79,350,349...79,523,393
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 decreases expression EXP Phenformin results in decreased expression of OSGIN1 mRNA CTD PMID:31324951 NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
JBrowse link
G Otud1 OTU deubiquitinase 1 decreases expression EXP Phenformin results in decreased expression of OTUD1 mRNA CTD PMID:31324951 NCBI chr17:82,259,881...82,262,774
Ensembl chr17:82,259,840...82,262,995
JBrowse link
G P2rx7 purinergic receptor P2X 7 increases expression EXP Phenformin results in increased expression of P2RX7 mRNA CTD PMID:31324951 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
JBrowse link
G P2ry2 purinergic receptor P2Y2 increases expression EXP Phenformin results in increased expression of P2RY2 mRNA CTD PMID:31324951 NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632
JBrowse link
G Paqr9 progestin and adipoQ receptor family member 9 decreases expression EXP Phenformin results in decreased expression of PAQR9 mRNA CTD PMID:31324951 NCBI chr 8:96,114,249...96,116,546 JBrowse link
G Pbk PDZ binding kinase decreases expression EXP Phenformin results in decreased expression of PBK mRNA CTD PMID:31324951 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
JBrowse link
G Pbld1 phenazine biosynthesis-like protein domain containing 1 increases expression EXP Phenformin results in increased expression of PBLD1 mRNA CTD PMID:31324951 NCBI chr20:25,551,274...25,566,543
Ensembl chr20:25,551,275...25,565,614
JBrowse link
G Pclaf PCNA clamp associated factor decreases expression EXP Phenformin results in decreased expression of PCLAF mRNA CTD PMID:31324951 NCBI chr 8:66,420,673...66,432,568
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994
JBrowse link
G Pde4b phosphodiesterase 4B increases expression EXP Phenformin results in increased expression of PDE4B mRNA CTD PMID:31324951 NCBI chr 5:116,799,827...117,367,707
Ensembl chr 5:116,799,971...117,367,696
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression EXP Phenformin results in increased expression of PDK4 mRNA CTD PMID:31324951 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
JBrowse link
G Pdlim1 PDZ and LIM domain 1 decreases expression EXP Phenformin results in decreased expression of PDLIM1 mRNA CTD PMID:31324951 NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076
JBrowse link
G Pdlim3 PDZ and LIM domain 3 decreases expression EXP Phenformin results in decreased expression of PDLIM3 mRNA CTD PMID:31324951 NCBI chr16:46,352,460...46,383,680
Ensembl chr16:46,352,467...46,383,657
JBrowse link
G Pdzrn3 PDZ domain containing RING finger 3 increases expression EXP Phenformin results in increased expression of PDZRN3 mRNA CTD PMID:31324951 NCBI chr 4:133,770,736...133,996,959
Ensembl chr 4:133,770,736...133,996,959
JBrowse link
G Penk proenkephalin increases expression EXP Phenformin results in increased expression of PENK mRNA CTD PMID:31324951 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129
JBrowse link
G Per1 period circadian regulator 1 decreases expression EXP Phenformin results in decreased expression of PER1 mRNA CTD PMID:31324951 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431
JBrowse link
G Per2 period circadian regulator 2 decreases expression EXP Phenformin results in decreased expression of PER2 mRNA CTD PMID:31324951 NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
JBrowse link
G Pex11a peroxisomal biogenesis factor 11 alpha increases expression EXP Phenformin results in increased expression of PEX11A mRNA CTD PMID:31324951 NCBI chr 1:133,680,091...133,687,172
Ensembl chr 1:133,680,091...133,687,172
JBrowse link
G Pex16 peroxisomal biogenesis factor 16 increases expression EXP Phenformin results in increased expression of PEX16 mRNA CTD PMID:31324951 NCBI chr 3:78,347,212...78,352,603
Ensembl chr 3:78,343,164...78,353,207
JBrowse link
G Pf4 platelet factor 4 decreases expression EXP Phenformin results in decreased expression of PF4 mRNA CTD PMID:31324951 NCBI chr14:17,298,438...17,299,148
Ensembl chr14:17,298,308...17,299,365
JBrowse link
G Pfkfb1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 decreases expression EXP Phenformin results in decreased expression of PFKFB1 mRNA CTD PMID:31324951 NCBI chr  X:19,508,522...19,562,165
Ensembl chr  X:19,508,546...19,562,182
JBrowse link
G Phtf1 putative homeodomain transcription factor 1 decreases expression EXP Phenformin results in decreased expression of PHTF1 mRNA CTD PMID:31324951 NCBI chr 2:191,470,849...191,537,399
Ensembl chr 2:191,473,130...191,512,078
JBrowse link
G Pi15 peptidase inhibitor 15 decreases expression EXP Phenformin results in decreased expression of PI15 mRNA CTD PMID:31324951 NCBI chr 5:1,395,094...1,423,213
Ensembl chr 5:1,395,094...1,423,213
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 decreases expression EXP Phenformin results in decreased expression of PIK3R1 mRNA CTD PMID:31324951 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pklr pyruvate kinase L/R decreases expression EXP Phenformin results in decreased expression of PKLR mRNA CTD PMID:31324951 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
JBrowse link
G Pla2g12a phospholipase A2, group XIIA increases expression EXP Phenformin results in increased expression of PLA2G12A mRNA CTD PMID:31324951 NCBI chr 2:218,436,450...218,452,760
Ensembl chr 2:218,436,513...218,452,740
JBrowse link
G Plcg1 phospholipase C, gamma 1 increases phosphorylation ISO Phenformin results in increased phosphorylation of PLCG1 protein CTD PMID:19901985 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Plin2 perilipin 2 decreases expression EXP Phenformin results in decreased expression of PLIN2 mRNA CTD PMID:31324951 NCBI chr 5:101,156,643...101,211,738
Ensembl chr 5:101,154,411...101,242,319
JBrowse link
G Plk1 polo-like kinase 1 decreases expression EXP Phenformin results in decreased expression of PLK1 mRNA CTD PMID:31324951 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Plppr1 phospholipid phosphatase related 1 decreases expression EXP Phenformin results in decreased expression of PLPPR1 mRNA CTD PMID:31324951 NCBI chr 5:63,437,457...63,725,286
Ensembl chr 5:63,437,816...63,763,835
JBrowse link
G Pnpla3 patatin-like phospholipase domain containing 3 decreases expression EXP Phenformin results in decreased expression of PNPLA3 mRNA CTD PMID:31324951 NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077
JBrowse link
G Por cytochrome p450 oxidoreductase decreases expression EXP Phenformin results in decreased expression of POR mRNA CTD PMID:31324951 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Potef POTE ankyrin domain family, member F decreases expression EXP Phenformin results in decreased expression of POTEF mRNA CTD PMID:31324951 NCBI chr18:23,626,518...23,629,132 JBrowse link
G Ppard peroxisome proliferator-activated receptor delta decreases expression EXP Phenformin results in decreased expression of PPARD mRNA CTD PMID:31324951 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Ppcs phosphopantothenoylcysteine synthetase increases expression EXP Phenformin results in increased expression of PPCS mRNA CTD PMID:31324951 NCBI chr 5:133,023,077...133,026,899
Ensembl chr 5:133,023,121...133,026,933
JBrowse link
G Ppm1k protein phosphatase, Mg2+/Mn2+ dependent, 1K increases expression EXP Phenformin results in increased expression of PPM1K mRNA CTD PMID:31324951 NCBI chr 4:87,612,198...87,638,993
Ensembl chr 4:87,612,204...87,636,152
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A decreases expression EXP Phenformin results in decreased expression of PPP1R15A mRNA CTD PMID:31324951 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ppp1r3b protein phosphatase 1, regulatory subunit 3B decreases expression EXP Phenformin results in decreased expression of PPP1R3B mRNA CTD PMID:31324951 NCBI chr16:56,830,011...56,842,395
Ensembl chr16:56,829,660...56,842,406
JBrowse link
G Prc1 protein regulator of cytokinesis 1 decreases expression EXP Phenformin results in decreased expression of PRC1 mRNA CTD PMID:31324951 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
JBrowse link
G Prim1 DNA primase subunit 1 decreases expression EXP Phenformin results in decreased expression of PRIM1 mRNA CTD PMID:31324951 NCBI chr 7:446,342...462,526
Ensembl chr 7:431,805...462,526
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 increases phosphorylation ISO Phenformin results in increased phosphorylation of PRKAA1 protein CTD PMID:19901985 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
JBrowse link
G Prox1 prospero homeobox 1 increases expression EXP Phenformin results in increased expression of PROX1 mRNA CTD PMID:31324951 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183
JBrowse link
G Prrg4 proline rich and Gla domain 4 decreases expression EXP Phenformin results in decreased expression of PRRG4 mRNA CTD PMID:31324951 NCBI chr 3:91,214,646...91,243,347
Ensembl chr 3:91,214,653...91,243,273
JBrowse link
G Psmb8 proteasome 20S subunit beta 8 increases expression EXP Phenformin results in increased expression of PSMB8 mRNA CTD PMID:31324951 NCBI chr20:4,652,159...4,655,122
Ensembl chr20:4,652,159...4,655,283
JBrowse link
G Ptk6 protein tyrosine kinase 6 decreases expression EXP Phenformin results in decreased expression of PTK6 mRNA CTD PMID:31324951 NCBI chr 3:168,307,073...168,315,664
Ensembl chr 3:168,307,073...168,315,664
JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 increases expression EXP Phenformin results in increased expression of PTPN3 mRNA CTD PMID:31324951 NCBI chr 5:71,908,520...72,027,323
Ensembl chr 5:71,911,135...72,065,443
JBrowse link
G Rab30 RAB30, member RAS oncogene family increases expression EXP Phenformin results in increased expression of RAB30 mRNA CTD PMID:31324951 NCBI chr 1:146,803,652...146,898,369
Ensembl chr 1:146,803,714...146,892,181
JBrowse link
G Rapgef5 Rap guanine nucleotide exchange factor 5 decreases expression EXP Phenformin results in decreased expression of RAPGEF5 mRNA CTD PMID:31324951 NCBI chr 6:138,445,127...138,679,943
Ensembl chr 6:138,437,991...138,679,936
JBrowse link
G Rcan1 regulator of calcineurin 1 decreases expression EXP Phenformin results in decreased expression of RCAN1 mRNA CTD PMID:31324951 NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045
JBrowse link
G Rdh5 retinol dehydrogenase 5 decreases expression EXP Phenformin results in decreased expression of RDH5 mRNA CTD PMID:31324951 NCBI chr 7:1,340,545...1,347,361 JBrowse link
G Reg3g regenerating family member 3 gamma increases expression EXP Phenformin results in increased expression of REG3G mRNA CTD PMID:31324951 NCBI chr 4:110,922,805...110,927,803
Ensembl chr 4:110,924,168...110,926,723
JBrowse link
G RGD1305184 similar to CDNA sequence BC023105 increases expression EXP Phenformin results in increased expression of RGD1305184 mRNA CTD PMID:31324951 NCBI chr18:53,838,426...53,854,858
Ensembl chr18:53,851,449...53,852,696
JBrowse link
G RGD1309362 similar to interferon-inducible GTPase increases expression EXP Phenformin results in increased expression of RGD1309362 mRNA CTD PMID:31324951
G RGD1309534 similar to RIKEN cDNA 4931406C07 decreases expression EXP Phenformin results in decreased expression of RGD1309534 mRNA CTD PMID:31324951 NCBI chr 8:12,123,839...12,146,412
Ensembl chr 8:12,123,823...12,146,473
JBrowse link
G RGD1559459 similar to Expressed sequence AI788959 increases expression EXP Phenformin results in increased expression of RGD1559459 mRNA CTD PMID:31324951 NCBI chr14:21,146,140...21,167,706
Ensembl chr14:21,145,827...21,167,704
JBrowse link
G RGD1560288 similar to DNA segment, Chr 19, Brigham & Womens Genetics 1357 expressed increases expression EXP Phenformin results in increased expression of RGD1560288 mRNA CTD PMID:31324951 NCBI chr12:16,357,131...16,359,221 JBrowse link
G RGD1560801 similar to guanylate binding protein 1, interferon-inducible, 67kDa increases expression EXP Phenformin results in increased expression of RGD1560801 mRNA CTD PMID:31324951 NCBI chr 2:231,517,485...231,525,865 JBrowse link
G RGD1563850 similar to Aldo-keto reductase family 1, member B8 decreases expression EXP Phenformin results in decreased expression of RGD1563850 mRNA CTD PMID:31324951 NCBI chr 6:77,569,720...77,571,967 JBrowse link
G Rgs2 regulator of G-protein signaling 2 decreases expression EXP Phenformin results in decreased expression of RGS2 mRNA CTD PMID:31324951 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Rp1 RP1, axonemal microtubule associated decreases expression EXP Phenformin results in decreased expression of RP1 mRNA CTD PMID:31324951 NCBI chr 5:15,121,104...15,582,363
Ensembl chr 5:15,121,133...15,579,363
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 decreases expression EXP Phenformin results in decreased expression of RRM2 mRNA CTD PMID:31324951 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G RT1-A RT1 class I, locus A decreases expression EXP Phenformin results in decreased expression of RT1-A mRNA CTD PMID:31324951
G Sbk1 SH3 domain binding kinase 1 increases expression EXP Phenformin results in increased expression of SBK1 mRNA CTD PMID:31324951 NCBI chr 1:180,807,092...180,851,910
Ensembl chr 1:180,807,099...180,851,885
JBrowse link
G Scarna15 small Cajal body-specific RNA 15 decreases expression EXP Phenformin results in decreased expression of SCARNA15 mRNA CTD PMID:31324951 NCBI chr 1:135,484,620...135,484,683 JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP Phenformin results in decreased expression of SCD1 mRNA CTD PMID:31324951 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Sdc4 syndecan 4 decreases expression EXP Phenformin results in decreased expression of SDC4 mRNA CTD PMID:31324951 NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580
JBrowse link
G Sdr42e1 short chain dehydrogenase/reductase family 42E, member 1 increases expression EXP Phenformin results in increased expression of SDR42E1 mRNA CTD PMID:31324951 NCBI chr19:45,715,366...45,727,901
Ensembl chr19:45,715,399...45,727,901
JBrowse link
G Sds serine dehydratase increases expression EXP Phenformin results in increased expression of SDS mRNA CTD PMID:31324951 NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
JBrowse link
G Serpina7 serpin family A member 7 increases expression EXP Phenformin results in increased expression of SERPINA7 mRNA CTD PMID:31324951 NCBI chr  X:102,663,242...102,722,319
Ensembl chr  X:102,663,405...102,669,040
JBrowse link
G Serpinc1 serpin family C member 1 increases activity ISO Phenformin results in increased activity of SERPINC1 protein CTD PMID:29458015 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293
JBrowse link
G Serpine1 serpin family E member 1 decreases expression EXP Phenformin results in decreased expression of SERPINE1 mRNA CTD PMID:31324951 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sik1 salt-inducible kinase 1 decreases expression EXP Phenformin results in decreased expression of SIK1 mRNA CTD PMID:31324951 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
JBrowse link
G Sirt1 sirtuin 1 decreases expression ISO Phenformin results in decreased expression of SIRT1 protein CTD PMID:26768367 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc10a2 solute carrier family 10 member 2 decreases expression EXP Phenformin results in decreased expression of SLC10A2 mRNA CTD PMID:31324951 NCBI chr16:84,386,528...84,409,475
Ensembl chr16:84,374,862...84,409,475
JBrowse link
G Slc10a5 solute carrier family 10, member 5 decreases expression EXP Phenformin results in decreased expression of SLC10A5 mRNA CTD PMID:31324951 NCBI chr 2:91,457,540...91,458,844
Ensembl chr 2:91,444,454...91,489,651
JBrowse link
G Slc13a2 solute carrier family 13 member 2 decreases expression EXP Phenformin results in decreased expression of SLC13A2 mRNA CTD PMID:31324951 NCBI chr10:63,291,813...63,319,127
Ensembl chr10:63,291,815...63,319,127
JBrowse link
G Slc13a3 solute carrier family 13 member 3 increases expression EXP Phenformin results in increased expression of SLC13A3 mRNA CTD PMID:31324951 NCBI chr 3:154,141,878...154,204,604
Ensembl chr 3:154,141,872...154,204,606
JBrowse link
G Slc16a10 solute carrier family 16 member 10 increases expression EXP Phenformin results in increased expression of SLC16A10 mRNA CTD PMID:31324951 NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839
JBrowse link
G Slc17a9 solute carrier family 17 member 9 decreases expression EXP Phenformin results in decreased expression of SLC17A9 mRNA CTD PMID:31324951 NCBI chr 3:167,839,246...167,857,462
Ensembl chr 3:167,839,385...167,855,985
JBrowse link
G Slc19a3 solute carrier family 19 member 3 multiple interactions ISO Phenformin inhibits the reaction [SLC19A3 protein results in increased uptake of Metformin]; Phenformin inhibits the reaction [SLC19A3 protein results in increased uptake of Thiamine] CTD PMID:26528626 NCBI chr 9:84,275,722...84,299,368
Ensembl chr 9:84,277,024...84,299,337
JBrowse link
G Slc1a2 solute carrier family 1 member 2 increases expression EXP Phenformin results in increased expression of SLC1A2 mRNA CTD PMID:31324951 NCBI chr 3:89,005,129...89,126,498
Ensembl chr 3:89,005,129...89,126,498
JBrowse link
G Slc1a4 solute carrier family 1 member 4 increases expression EXP Phenformin results in increased expression of SLC1A4 mRNA CTD PMID:31324951 NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Phenformin inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc22a23 solute carrier family 22, member 23 decreases expression EXP Phenformin results in decreased expression of SLC22A23 mRNA CTD PMID:31324951 NCBI chr17:30,544,106...30,709,790
Ensembl chr17:30,544,106...30,709,790
JBrowse link
G Slc22a4 solute carrier family 22 member 4 increases response to substance
affects uptake
ISO SLC22A4 protein results in increased susceptibility to Phenformin
SLC22A4 protein affects the uptake of Phenformin
CTD PMID:23221006 NCBI chr10:38,133,333...38,179,932 JBrowse link
G Slc22a5 solute carrier family 22 member 5 increases expression EXP Phenformin results in increased expression of SLC22A5 mRNA CTD PMID:31324951 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
JBrowse link
G Slc25a23 solute carrier family 25 member 23 decreases expression EXP Phenformin results in decreased expression of SLC25A23 mRNA CTD PMID:31324951 NCBI chr 9:1,882,636...1,898,340
Ensembl chr 9:1,882,621...1,898,561
JBrowse link
G Slc25a47 solute carrier family 25, member 47 increases expression EXP Phenformin results in increased expression of SLC25A47 mRNA CTD PMID:31324951 NCBI chr 6:127,767,365...127,773,000
Ensembl chr 6:127,767,305...127,773,005
JBrowse link
G Slc27a1 solute carrier family 27 member 1 increases expression EXP Phenformin results in increased expression of SLC27A1 mRNA CTD PMID:31324951 NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
JBrowse link
G Slc2a12 solute carrier family 2 member 12 increases expression EXP Phenformin results in increased expression of SLC2A12 mRNA CTD PMID:31324951 NCBI chr 1:22,803,068...22,862,204
Ensembl chr 1:22,804,418...22,860,971
JBrowse link
G Slc2a5 solute carrier family 2 member 5 decreases expression EXP Phenformin results in decreased expression of SLC2A5 mRNA CTD PMID:31324951 NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106
JBrowse link
G Slc34a2 solute carrier family 34 member 2 decreases expression EXP Phenformin results in decreased expression of SLC34A2 mRNA CTD PMID:31324951 NCBI chr14:57,910,931...57,930,236
Ensembl chr14:57,910,480...57,930,436
JBrowse link
G Slc35c2 solute carrier family 35 member C2 decreases expression EXP Phenformin results in decreased expression of SLC35C2 mRNA CTD PMID:31324951 NCBI chr 3:154,012,262...154,023,549
Ensembl chr 3:154,012,416...154,023,488
JBrowse link
G Slc38a2 solute carrier family 38, member 2 decreases expression EXP Phenformin results in decreased expression of SLC38A2 mRNA CTD PMID:31324951 NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436
JBrowse link
G Slc47a1 solute carrier family 47 member 1 multiple interactions ISO Phenformin inhibits the reaction [SLC47A1 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:46,034,115...46,088,617
Ensembl chr10:46,034,122...46,087,637
JBrowse link
G Slc47a2 solute carrier family 47 member 2 multiple interactions ISO Phenformin inhibits the reaction [SLC47A2 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] CTD PMID:22419765 NCBI chr10:45,990,806...46,033,937
Ensembl chr10:45,991,095...46,033,904
JBrowse link
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) decreases expression EXP Phenformin results in decreased expression of SLC4A1 mRNA CTD PMID:31324951 NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117
JBrowse link
G Slc4a4 solute carrier family 4 member 4 increases expression EXP Phenformin results in increased expression of SLC4A4 mRNA CTD PMID:31324951 NCBI chr14:18,841,289...19,293,297
Ensembl chr14:18,845,159...19,272,883
JBrowse link
G Slc6a6 solute carrier family 6 member 6 increases expression EXP Phenformin results in increased expression of SLC6A6 mRNA CTD PMID:31324951 NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
JBrowse link
G Smco1 single-pass membrane protein with coiled-coil domains 1 increases expression EXP Phenformin results in increased expression of SMCO1 mRNA CTD PMID:31324951 NCBI chr11:68,512,113...68,514,999
Ensembl chr11:68,509,150...68,515,003
JBrowse link
G Snai2 snail family transcriptional repressor 2 increases expression EXP Phenformin results in increased expression of SNAI2 mRNA CTD PMID:31324951 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Sntb1 syntrophin, beta 1 increases expression EXP Phenformin results in increased expression of SNTB1 mRNA CTD PMID:31324951 NCBI chr 7:87,060,926...87,329,315
Ensembl chr 7:87,060,926...87,329,315
JBrowse link
G Socs2 suppressor of cytokine signaling 2 decreases expression EXP Phenformin results in decreased expression of SOCS2 mRNA CTD PMID:31324951 NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548
JBrowse link
G Spink1 serine peptidase inhibitor, Kazal type 1 increases expression EXP Phenformin results in increased expression of SPINK1 mRNA CTD PMID:31324951 NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression EXP Phenformin results in decreased expression of SREBF1 mRNA CTD PMID:31324951 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Stac3 SH3 and cysteine rich domain 3 decreases expression EXP Phenformin results in decreased expression of STAC3 mRNA CTD PMID:31324951 NCBI chr 7:63,343,078...63,350,590
Ensembl chr 7:63,343,186...63,350,589
JBrowse link
G Stat3 signal transducer and activator of transcription 3 increases expression EXP Phenformin results in increased expression of STAT3 mRNA CTD PMID:31324951 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stat5b signal transducer and activator of transcription 5B decreases activity ISO Phenformin results in decreased activity of STAT5B protein CTD PMID:30114225 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
JBrowse link
G Stmn1 stathmin 1 decreases expression EXP Phenformin results in decreased expression of STMN1 mRNA CTD PMID:31324951 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Stxbp6 syntaxin binding protein 6 increases expression EXP Phenformin results in increased expression of STXBP6 mRNA CTD PMID:31324951 NCBI chr 6:61,920,756...62,157,405
Ensembl chr 6:61,920,756...62,158,024
JBrowse link
G Tbx3 T-box transcription factor 3 increases expression EXP Phenformin results in increased expression of TBX3 mRNA CTD PMID:31324951 NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
JBrowse link
G Tcap titin-cap increases expression EXP Phenformin results in increased expression of TCAP mRNA CTD PMID:31324951 NCBI chr10:83,381,719...83,382,887
Ensembl chr10:83,381,719...83,382,887
JBrowse link
G Tex36 testis expressed 36 increases expression EXP Phenformin results in increased expression of TEX36 mRNA CTD PMID:31324951 NCBI chr 1:188,390,062...188,404,448
Ensembl chr 1:188,390,064...188,404,377
JBrowse link
G Thbs1 thrombospondin 1 increases expression EXP Phenformin results in increased expression of THBS1 mRNA CTD PMID:31324951 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Thrsp thyroid hormone responsive decreases expression EXP Phenformin results in decreased expression of THRSP mRNA CTD PMID:31324951 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
JBrowse link
G Tk1 thymidine kinase 1 decreases expression EXP Phenformin results in decreased expression of TK1 mRNA CTD PMID:31324951 NCBI chr10:103,034,755...103,046,125
Ensembl chr10:103,031,521...103,046,920
JBrowse link
G Tkfc triokinase and FMN cyclase decreases expression EXP Phenformin results in decreased expression of TKFC mRNA CTD PMID:31324951 NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737
JBrowse link
G Tm7sf2 transmembrane 7 superfamily member 2 increases expression EXP Phenformin results in increased expression of TM7SF2 mRNA CTD PMID:31324951 NCBI chr 1:203,355,930...203,360,287
Ensembl chr 1:203,355,931...203,360,270
JBrowse link
G Tmem30b transmembrane protein 30B increases expression EXP Phenformin results in increased expression of TMEM30B mRNA CTD PMID:31324951 NCBI chr 6:92,251,626...92,254,702
Ensembl chr 6:92,249,790...92,254,842
JBrowse link
G Tmem37 transmembrane protein 37 decreases expression EXP Phenformin results in decreased expression of TMEM37 mRNA CTD PMID:31324951 NCBI chr13:31,184,322...31,191,477
Ensembl chr13:31,171,355...31,191,077
JBrowse link
G Tmod4 tropomodulin 4 increases expression EXP Phenformin results in increased expression of TMOD4 mRNA CTD PMID:31324951 NCBI chr 2:182,695,709...182,700,540
Ensembl chr 2:182,695,709...182,700,540
JBrowse link
G Tnfaip2 TNF alpha induced protein 2 increases expression EXP Phenformin results in increased expression of TNFAIP2 mRNA CTD PMID:31324951 NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 decreases expression EXP Phenformin results in decreased expression of TNFAIP3 mRNA CTD PMID:31324951 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tnfsf13 TNF superfamily member 13 decreases expression EXP Phenformin results in decreased expression of TNFSF13 mRNA CTD PMID:31324951 NCBI chr10:54,400,054...54,403,723
Ensembl chr10:54,400,065...54,403,042
JBrowse link
G Tob2 transducer of ERBB2, 2 decreases expression EXP Phenformin results in decreased expression of TOB2 mRNA CTD PMID:31324951 NCBI chr 7:113,362,703...113,371,423
Ensembl chr 7:113,361,148...113,372,688
JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression EXP Phenformin results in decreased expression of TOP2A mRNA CTD PMID:31324951 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 decreases expression EXP Phenformin results in decreased expression of TP53INP1 mRNA CTD PMID:31324951 NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968
JBrowse link
G Tppp tubulin polymerization promoting protein decreases expression EXP Phenformin results in decreased expression of TPPP mRNA CTD PMID:31324951 NCBI chr 1:29,257,111...29,281,134
Ensembl chr 1:29,261,255...29,281,134
JBrowse link
G Tpx2 TPX2, microtubule nucleation factor decreases expression EXP Phenformin results in decreased expression of TPX2 mRNA CTD PMID:31324951 NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468
JBrowse link
G Trim24 tripartite motif-containing 24 increases expression EXP Phenformin results in increased expression of TRIM24 mRNA CTD PMID:31324951 NCBI chr 4:66,664,864...66,717,244
Ensembl chr 4:66,566,686...66,717,241
JBrowse link
G Trim50 tripartite motif-containing 50 increases expression EXP Phenformin results in increased expression of TRIM50 mRNA CTD PMID:31324951 NCBI chr12:21,300,784...21,317,668
Ensembl chr12:21,300,785...21,317,668
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 decreases expression EXP Phenformin results in decreased expression of TSC22D3 mRNA CTD PMID:31324951 NCBI chr  X:104,217,898...104,277,935
Ensembl chr  X:104,217,925...104,276,861
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan decreases expression EXP Phenformin results in decreased expression of TSKU mRNA CTD PMID:31324951 NCBI chr 1:152,660,259...152,671,682
Ensembl chr 1:152,656,693...152,672,588
JBrowse link
G Tspan4 tetraspanin 4 decreases expression EXP Phenformin results in decreased expression of TSPAN4 mRNA CTD PMID:31324951 NCBI chr 1:196,571,307...196,593,842
Ensembl chr 1:196,572,228...196,617,448
JBrowse link
G Ttk Ttk protein kinase decreases expression EXP Phenformin results in decreased expression of TTK mRNA CTD PMID:31324951 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
JBrowse link
G Tubb1 tubulin, beta 1 class VI decreases expression EXP Phenformin results in decreased expression of TUBB1 mRNA CTD PMID:31324951 NCBI chr 3:163,247,990...163,257,460
Ensembl chr 3:163,247,967...163,256,063
JBrowse link
G Tubb2a tubulin, beta 2A class IIa decreases expression EXP Phenformin results in decreased expression of TUBB2A mRNA CTD PMID:31324951 NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
JBrowse link
G Txnip thioredoxin interacting protein increases expression EXP Phenformin results in increased expression of TXNIP mRNA CTD PMID:31324951 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C decreases expression EXP Phenformin results in decreased expression of UBE2C mRNA CTD PMID:31324951 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
JBrowse link
G Ucp3 uncoupling protein 3 increases expression EXP Phenformin results in increased expression of UCP3 mRNA CTD PMID:31324951 NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762
JBrowse link
G Ugdh UDP-glucose 6-dehydrogenase decreases expression EXP Phenformin results in decreased expression of UGDH protein CTD PMID:4270849 NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354
JBrowse link
G Ugt2a3 UDP glucuronosyltransferase family 2 member A3 increases expression EXP Phenformin results in increased expression of UGT2A3 mRNA CTD PMID:31324951 NCBI chr14:20,572,825...20,590,295
Ensembl chr14:20,572,808...20,590,729
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases expression EXP Phenformin results in increased expression of UGT2B1 mRNA CTD PMID:31324951 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Upp2 uridine phosphorylase 2 increases expression EXP Phenformin results in increased expression of UPP2 mRNA CTD PMID:31324951 NCBI chr 3:43,273,048...43,317,417
Ensembl chr 3:43,273,048...43,317,417
JBrowse link
G Usp18 ubiquitin specific peptidase 18 increases expression EXP Phenformin results in increased expression of USP18 mRNA CTD PMID:31324951 NCBI chr 4:154,471,634...154,499,154
Ensembl chr 4:154,471,592...154,499,144
JBrowse link
G Usp2 ubiquitin specific peptidase 2 decreases expression EXP Phenformin results in decreased expression of USP2 mRNA CTD PMID:31324951 NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331
JBrowse link
G Vgll4 vestigial-like family member 4 decreases expression EXP Phenformin results in decreased expression of VGLL4 mRNA CTD PMID:31324951 NCBI chr 4:147,925,630...148,038,514
Ensembl chr 4:147,927,034...148,038,471
JBrowse link
G Vnn1 vanin 1 increases expression EXP Phenformin results in increased expression of VNN1 mRNA CTD PMID:31324951 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase decreases expression EXP Phenformin results in decreased expression of WEE1 mRNA CTD PMID:31324951 NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688
JBrowse link
G Xiap X-linked inhibitor of apoptosis increases expression EXP Phenformin results in increased expression of XIAP mRNA CTD PMID:31324951 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
G Ypel2 yippee-like 2 decreases expression EXP Phenformin results in decreased expression of YPEL2 mRNA CTD PMID:31324951 NCBI chr10:71,746,308...71,803,855
Ensembl chr10:71,746,311...71,803,911
JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 decreases expression EXP Phenformin results in decreased expression of ZBTB16 mRNA CTD PMID:31324951 NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
JBrowse link
G Zfp354a zinc finger protein 354A decreases expression EXP Phenformin results in decreased expression of ZFP354A mRNA CTD PMID:31324951 NCBI chr10:35,396,242...35,408,065
Ensembl chr10:35,396,231...35,408,068
JBrowse link
G Zfp36 zinc finger protein 36 decreases expression EXP Phenformin results in decreased expression of ZFP36 mRNA CTD PMID:31324951 NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
JBrowse link
G Znf750 zinc finger protein 750 increases expression EXP Phenformin results in increased expression of ZNF750 mRNA CTD PMID:31324951 NCBI chr10:106,772,162...106,781,186
Ensembl chr10:106,772,669...106,781,200
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      application 19498
        pharmaceutical 19356
          drug 19356
            antineoplastic agent 17359
              phenformin 424
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            heteroorganic entity 19278
                              organonitrogen compound 18544
                                guanidines 2221
                                  biguanide 1067
                                    phenformin 424
paths to the root