CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: malic acid
Accession: CHEBI:6650
browse the term
Definition: A 2-hydroxydicarboxylic acid that is succinic acid in which one of the hydrogens attached to a carbon is replaced by a hydroxy group.
Synonyms: related_synonym: 2-Hydroxybutanedioic acid; 2-Hydroxyethane-1,2-dicarboxylic acid; 2-Hydroxysuccinic acid; Aepfelsaeure; DL-Malic acid; E296; Formula=C4H6O5; H2mal; InChI=1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9); InChIKey=BJEPYKJPYRNKOW-UHFFFAOYSA-N; SMILES=OC(CC(O)=O)C(O)=O; alpha-hydroxysuccinic acid; apple acid; hydroxybutanedioic acid; hydroxysuccinic acid
xref: Beilstein:1723539; CAS:6915-15-7; Gmelin:3325; HMDB:HMDB0000744; KEGG:C00711; KEGG:D04843
xref_mesh: MESH:C030298
xref: MetaCyc:RS-Malate; PMID:15767321; PMID:17190852; PMID:17439666; PMID:17896933; PMID:19743855; PMID:22411507; PPDB:1352; Reaxys:1723539; Wikipedia:Malic_acid
cyclic_relationship: is_conjugate_acid_of CHEBI:15595; is_conjugate_acid_of CHEBI:25115
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Idh2
isocitrate dehydrogenase (NADP(+)) 2
multiple interactions decreases abundance
ISO
Triazines inhibits the reaction [IDH2 protein mutant form results in decreased abundance of malic acid]
CTD
PMID:27469509
NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
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Mdh1
malate dehydrogenase 1
increases expression
ISO
malic acid deficiency results in increased expression of MDH1 mRNA
CTD
PMID:26811028
NCBI chr14:106,378,349...106,393,642
Ensembl chr14:106,378,942...106,393,670
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Nr1h4
nuclear receptor subfamily 1, group H, member 4
multiple interactions
ISO
[[NR1H4 protein co-treated with Dietary Fats] results in increased susceptibility to caffeic acid phenethyl ester] which results in increased abundance of malic acid
CTD
PMID:28223344
NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
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Ppargc1a
PPARG coactivator 1 alpha
increases expression
ISO
malic acid results in increased expression of PPARGC1A mRNA
CTD
PMID:23056435
NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
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Acta2
actin alpha 2, smooth muscle
affects expression
ISO
diethyl malate affects the expression of ACTA2 mRNA
CTD
PMID:24814887
NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
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Actc1
actin, alpha, cardiac muscle 1
affects expression
ISO
diethyl malate affects the expression of ACTC1 mRNA
CTD
PMID:24814887
NCBI chr 3:105,507,403...105,512,939
Ensembl chr 3:105,507,403...105,512,939
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Actn3
actinin alpha 3
affects expression
ISO
diethyl malate affects the expression of ACTN3 mRNA
CTD
PMID:24814887
NCBI chr 1:220,120,532...220,136,460
Ensembl chr 1:220,120,533...220,136,470
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Adcy1
adenylate cyclase 1
affects expression
ISO
diethyl malate affects the expression of ADCY1 mRNA
CTD
PMID:24814887
NCBI chr14:87,311,970...87,429,880
Ensembl chr14:87,312,203...87,421,659
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Adh1
alcohol dehydrogenase 1 (class I)
affects expression
ISO
diethyl malate affects the expression of ADH1 mRNA
CTD
PMID:24814887
NCBI chr 2:243,550,655...243,562,243
Ensembl chr 2:243,550,627...243,687,857
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Agt
angiotensinogen
affects expression
ISO
diethyl malate affects the expression of AGT mRNA
CTD
PMID:24814887
NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
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C3
complement C3
affects expression
ISO
diethyl malate affects the expression of C3 mRNA
CTD
PMID:24814887
NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
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Cacnb2
calcium voltage-gated channel auxiliary subunit beta 2
affects expression
ISO
diethyl malate affects the expression of CACNB2 mRNA
CTD
PMID:24814887
NCBI chr17:81,673,862...82,019,219
Ensembl chr17:81,798,756...82,017,682
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Cacnb4
calcium voltage-gated channel auxiliary subunit beta 4
affects expression
ISO
diethyl malate affects the expression of CACNB4 mRNA
CTD
PMID:24814887
NCBI chr 3:37,950,846...38,211,478
Ensembl chr 3:37,955,069...38,090,526
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Camk2a
calcium/calmodulin-dependent protein kinase II alpha
multiple interactions affects expression
ISO
S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of CAMK2A mRNA]
CTD
PMID:24814887
NCBI chr18:56,193,978...56,295,869
Ensembl chr18:56,193,978...56,295,869
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Ccl20
C-C motif chemokine ligand 20
affects expression
ISO
diethyl malate affects the expression of CCL20 mRNA
CTD
PMID:24814887
NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
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Ccl6
C-C motif chemokine ligand 6
affects expression
ISO
diethyl malate affects the expression of CCL6 mRNA
CTD
PMID:24814887
NCBI chr10:70,798,118...70,802,750
Ensembl chr10:70,797,124...70,802,782
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Ccl7
C-C motif chemokine ligand 7
affects expression
ISO
diethyl malate affects the expression of CCL7 mRNA
CTD
PMID:24814887
NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
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Col11a1
collagen type XI alpha 1 chain
affects expression
ISO
diethyl malate affects the expression of COL11A1 mRNA
CTD
PMID:24814887
NCBI chr 2:216,863,423...217,056,523
Ensembl chr 2:216,863,428...217,056,523
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Col2a1
collagen type II alpha 1 chain
affects expression
ISO
diethyl malate affects the expression of COL2A1 mRNA
CTD
PMID:24814887
NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
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Col3a1
collagen type III alpha 1 chain
affects expression
ISO
diethyl malate affects the expression of COL3A1 mRNA
CTD
PMID:24814887
NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
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Col6a1
collagen type VI alpha 1 chain
affects expression
ISO
diethyl malate affects the expression of COL6A1 mRNA
CTD
PMID:24814887
NCBI chr20:12,657,913...12,676,370
Ensembl chr20:12,658,065...12,675,561
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Comp
cartilage oligomeric matrix protein
affects expression
ISO
diethyl malate affects the expression of COMP mRNA
CTD
PMID:24814887
NCBI chr16:20,798,437...20,807,070
Ensembl chr16:20,798,437...20,807,070
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Cxcl12
C-X-C motif chemokine ligand 12
affects expression multiple interactions
ISO
diethyl malate affects the expression of CXCL12 mRNA S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of CXCL12 mRNA]
CTD
PMID:24814887
NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
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Cxcl3
C-X-C motif chemokine ligand 3
affects expression
ISO
diethyl malate affects the expression of CXCL1 mRNA
CTD
PMID:24814887
NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
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Cyp2j4
cytochrome P450, family 2, subfamily j, polypeptide 4
affects expression
ISO
diethyl malate affects the expression of CYP2J9 mRNA
CTD
PMID:24814887
NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
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Dapk2
death-associated protein kinase 2
affects expression
ISO
diethyl malate affects the expression of DAPK2 mRNA
CTD
PMID:24814887
NCBI chr 8:71,822,107...71,941,941
Ensembl chr 8:71,822,129...71,941,910
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Ddx58
DEXD/H-box helicase 58
affects expression
ISO
diethyl malate affects the expression of DDX58 mRNA
CTD
PMID:24814887
NCBI chr 5:56,486,584...56,536,898
Ensembl chr 5:56,500,734...56,536,772
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Dhrs3
dehydrogenase/reductase 3
affects expression
ISO
diethyl malate affects the expression of DHRS3 mRNA
CTD
PMID:24814887
NCBI chr 5:162,809,090...162,843,385
Ensembl chr 5:162,808,646...162,843,383
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Dhx58
DEXH-box helicase 58
affects expression
ISO
diethyl malate affects the expression of DHX58 mRNA
CTD
PMID:24814887
NCBI chr10:88,599,722...88,611,562
Ensembl chr10:88,599,680...88,611,105
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Edar
ectodysplasin-A receptor
affects expression
ISO
diethyl malate affects the expression of EDAR mRNA
CTD
PMID:24814887
NCBI chr20:28,179,132...28,263,092
Ensembl chr20:28,179,140...28,263,037
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Ednra
endothelin receptor type A
affects expression
ISO
diethyl malate affects the expression of EDNRA mRNA
CTD
PMID:24814887
NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
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Epas1
endothelial PAS domain protein 1
affects expression
ISO
diethyl malate affects the expression of EPAS1 mRNA
CTD
PMID:24814887
NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
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Epha7
Eph receptor A7
affects expression
ISO
diethyl malate affects the expression of EPHA7 mRNA
CTD
PMID:24814887
NCBI chr 5:43,602,744...43,761,198
Ensembl chr 5:43,603,043...43,757,549
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Ephb2
Eph receptor B2
affects expression
ISO
diethyl malate affects the expression of EPHB2 mRNA
CTD
PMID:24814887
NCBI chr 5:155,024,478...155,143,539
Ensembl chr 5:155,022,493...155,204,456
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Ephb6
Eph receptor B6
affects expression
ISO
diethyl malate affects the expression of EPHB6 mRNA
CTD
PMID:24814887
NCBI chr 4:70,903,253...70,918,514
Ensembl chr 4:70,903,253...70,918,514
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Fgf10
fibroblast growth factor 10
affects expression
ISO
diethyl malate affects the expression of FGF10 mRNA
CTD
PMID:24814887
NCBI chr 2:51,673,480...51,747,533
Ensembl chr 2:51,672,722...51,750,369
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Fgf18
fibroblast growth factor 18
multiple interactions affects expression
ISO
S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of FGF18 mRNA]
CTD
PMID:24814887
NCBI chr10:18,047,109...18,082,290
Ensembl chr10:18,047,109...18,063,391
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Fgfr2
fibroblast growth factor receptor 2
affects expression
ISO
diethyl malate affects the expression of FGFR2 mRNA
CTD
PMID:24814887
NCBI chr 1:200,590,951...200,696,946
Ensembl chr 1:200,590,953...200,696,928
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Fst
follistatin
affects expression
ISO
diethyl malate affects the expression of FST mRNA
CTD
PMID:24814887
NCBI chr 2:46,537,589...46,544,813
Ensembl chr 2:46,538,700...46,544,457
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Fzd2
frizzled class receptor 2
affects expression
ISO
diethyl malate affects the expression of FZD2 mRNA
CTD
PMID:24814887
NCBI chr10:90,550,147...90,552,057
Ensembl chr10:90,550,147...90,552,057
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Fzd7
frizzled class receptor 7
affects expression
ISO
diethyl malate affects the expression of FZD7 mRNA
CTD
PMID:24814887
NCBI chr 9:66,305,731...66,308,550
Ensembl chr 9:66,305,731...66,308,550
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Gclc
glutamate-cysteine ligase, catalytic subunit
affects expression
ISO
diethyl malate affects the expression of GCLC mRNA
CTD
PMID:24814887
NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
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Gclm
glutamate cysteine ligase, modifier subunit
multiple interactions affects expression
ISO
S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of GCLM mRNA]
CTD
PMID:24814887
NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
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Ggt6
gamma-glutamyl transferase 6
affects expression
ISO
diethyl malate affects the expression of GGT6 mRNA
CTD
PMID:24814887
NCBI chr10:58,995,253...58,998,431
Ensembl chr10:58,995,556...58,998,033
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Gli2
GLI family zinc finger 2
affects expression
ISO
diethyl malate affects the expression of GLI2 mRNA
CTD
PMID:24814887
NCBI chr13:34,829,021...35,049,172
Ensembl chr13:34,829,139...35,048,444
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Gnao1
G protein subunit alpha o1
affects expression
ISO
diethyl malate affects the expression of GNAO1 mRNA
CTD
PMID:24814887
NCBI chr19:11,513,201...11,669,578
Ensembl chr19:11,513,201...11,669,578
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Gng7
G protein subunit gamma 7
affects expression
ISO
diethyl malate affects the expression of GNG7 mRNA
CTD
PMID:24814887
NCBI chr 7:11,565,740...11,629,519
Ensembl chr 7:11,582,984...11,628,929
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Gsr
glutathione-disulfide reductase
affects expression
ISO
diethyl malate affects the expression of GSR mRNA
CTD
PMID:24814887
NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
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Gss
glutathione synthetase
multiple interactions affects expression
ISO
S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of GSS mRNA]
CTD
PMID:24814887
NCBI chr 3:151,076,254...151,106,557
Ensembl chr 3:151,076,254...151,106,557
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Gsta2
glutathione S-transferase alpha 2
affects expression multiple interactions
ISO
diethyl malate affects the expression of GSTA1 mRNA S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of GSTA1 mRNA]
CTD
PMID:24814887
NCBI chr 8:85,640,081...85,645,621
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Gsta3
glutathione S-transferase alpha 3
affects expression multiple interactions
ISO
diethyl malate affects the expression of GSTA3 mRNA S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of GSTA3 mRNA]
CTD
PMID:24814887
NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
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Gsta6
glutathione S-transferase alpha 6
affects expression multiple interactions
ISO
diethyl malate affects the expression of GSTA1 mRNA S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of GSTA1 mRNA]
CTD
PMID:24814887
NCBI chr 9:27,475,273...27,533,939
Ensembl chr 9:27,475,273...27,511,176
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Gucy1a1
guanylate cyclase 1 soluble subunit alpha 1
affects expression
ISO
diethyl malate affects the expression of GUCY1A1 mRNA
CTD
PMID:24814887
NCBI chr 2:181,045,694...181,103,321
Ensembl chr 2:181,045,703...181,102,918
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Gucy1b1
guanylate cyclase 1 soluble subunit beta 1
affects expression
ISO
diethyl malate affects the expression of GUCY1B1 mRNA
CTD
PMID:24814887
NCBI chr 2:180,976,939...181,026,001
Ensembl chr 2:180,976,939...181,026,024
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Hck
HCK proto-oncogene, Src family tyrosine kinase
affects expression
ISO
diethyl malate affects the expression of HCK mRNA
CTD
PMID:24814887
NCBI chr 3:148,579,917...148,623,026
Ensembl chr 3:148,579,920...148,623,033
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Hgf
hepatocyte growth factor
affects expression
ISO
diethyl malate affects the expression of HGF mRNA
CTD
PMID:24814887
NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
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Igf1
insulin-like growth factor 1
affects expression
ISO
diethyl malate affects the expression of IGF1 mRNA
CTD
PMID:24814887
NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
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Il15
interleukin 15
affects expression
ISO
diethyl malate affects the expression of IL15 mRNA
CTD
PMID:24814887
NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594
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Il18
interleukin 18
affects expression
ISO
diethyl malate affects the expression of IL18 mRNA
CTD
PMID:24814887
NCBI chr 8:55,009,666...55,016,286
Ensembl chr 8:54,993,859...55,016,299
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Irag1
inositol 1,4,5-triphosphate receptor associated 1
affects expression
ISO
diethyl malate affects the expression of IRAG1 mRNA
CTD
PMID:24814887
NCBI chr 1:175,681,960...175,804,737
Ensembl chr 1:175,681,960...175,796,040
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Irf7
interferon regulatory factor 7
affects expression
ISO
diethyl malate affects the expression of IRF7 mRNA
CTD
PMID:24814887
NCBI chr 1:214,249,388...214,252,909
Ensembl chr 1:214,248,837...214,252,456
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Isg15
ISG15 ubiquitin-like modifier
affects expression
ISO
diethyl malate affects the expression of ISG15 mRNA
CTD
PMID:24814887
NCBI chr 5:173,624,862...173,629,124
Ensembl chr 5:173,624,310...173,626,248
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Itga11
integrin subunit alpha 11
affects expression
ISO
diethyl malate affects the expression of ITGA11 mRNA
CTD
PMID:24814887
NCBI chr 8:67,566,874...67,683,973
Ensembl chr 8:67,615,635...67,683,973
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Itga3
integrin subunit alpha 3
affects expression
ISO
diethyl malate affects the expression of ITGA3 mRNA
CTD
PMID:24814887
NCBI chr10:82,855,841...82,887,755
Ensembl chr10:82,855,613...82,887,497
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Kcnmb4
potassium calcium-activated channel subfamily M regulatory beta subunit 4
affects expression
ISO
diethyl malate affects the expression of KCNMB4 mRNA
CTD
PMID:24814887
NCBI chr 7:59,461,808...59,514,759
Ensembl chr 7:59,461,799...59,514,939
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Lama1
laminin subunit alpha 1
affects expression
ISO
diethyl malate affects the expression of LAMA1 mRNA
CTD
PMID:24814887
NCBI chr 9:115,916,907...116,042,123
Ensembl chr 9:115,916,907...116,042,123
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Lama4
laminin subunit alpha 4
affects expression
ISO
diethyl malate affects the expression of LAMA4 mRNA
CTD
PMID:24814887
NCBI chr20:44,060,715...44,201,966
Ensembl chr20:44,060,731...44,209,614
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LOC100909797
RT1 class I histocompatibility antigen, AA alpha chain-like
affects expression
ISO
diethyl malate affects the expression of H2-M3 mRNA
CTD
PMID:24814887
NCBI chr20:3,242,236...3,253,995
Ensembl chr20:3,242,470...3,249,189
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Mapk1
mitogen activated protein kinase 1
affects phosphorylation multiple interactions
ISO
diethyl malate affects the phosphorylation of MAPK1 protein S-ethyl glutathione inhibits the reaction [diethyl malate affects the phosphorylation of MAPK1 protein]
CTD
PMID:24814887
NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
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Mapk3
mitogen activated protein kinase 3
affects phosphorylation multiple interactions
ISO
diethyl malate affects the phosphorylation of MAPK3 protein S-ethyl glutathione inhibits the reaction [diethyl malate affects the phosphorylation of MAPK3 protein]
CTD
PMID:24814887
NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
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Myl9
myosin light chain 9
affects expression
ISO
diethyl malate affects the expression of MYL9 mRNA
CTD
PMID:24814887
NCBI chr 3:152,857,573...152,863,961
Ensembl chr 3:152,857,592...152,863,960
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Odc1
ornithine decarboxylase 1
affects expression
ISO
diethyl malate affects the expression of ODC1 mRNA
CTD
PMID:24814887
NCBI chr 6:42,852,529...42,859,142
Ensembl chr 6:42,852,683...42,859,927
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Pdgfb
platelet derived growth factor subunit B
affects expression multiple interactions
ISO
diethyl malate affects the expression of PDGFB mRNA S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of PDGFB mRNA]
CTD
PMID:24814887
NCBI chr 7:121,215,458...121,233,092
Ensembl chr 7:121,214,628...121,232,741
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Pdgfd
platelet derived growth factor D
affects expression
ISO
diethyl malate affects the expression of PDGFD mRNA
CTD
PMID:24814887
NCBI chr 8:4,441,010...4,666,754
Ensembl chr 8:4,440,876...4,669,014
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Pf4
platelet factor 4
affects expression
ISO
diethyl malate affects the expression of PF4 mRNA
CTD
PMID:24814887
NCBI chr14:18,848,549...18,849,258
Ensembl chr14:18,848,549...18,849,258
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Pik3ip1
phosphoinositide-3-kinase interacting protein 1
affects expression
ISO
diethyl malate affects the expression of PIK3IP1 mRNA
CTD
PMID:24814887
NCBI chr14:83,559,397...83,572,481
Ensembl chr14:83,560,541...83,572,473
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Plxnc1
plexin C1
affects expression
ISO
diethyl malate affects the expression of PLXNC1 mRNA
CTD
PMID:24814887
NCBI chr 7:35,848,083...36,000,969
Ensembl chr 7:35,850,398...36,000,906
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Prkg1
protein kinase cGMP-dependent 1
affects expression
ISO
diethyl malate affects the expression of PRKG1 mRNA
CTD
PMID:24814887
NCBI chr 1:248,982,039...250,300,952
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Ptgis
prostaglandin I2 synthase
affects expression
ISO
diethyl malate affects the expression of PTGIS mRNA
CTD
PMID:24814887
NCBI chr 3:163,950,746...163,986,129
G
Ramp2
receptor activity modifying protein 2
affects expression
ISO
diethyl malate affects the expression of RAMP2 mRNA
CTD
PMID:24814887
NCBI chr10:89,166,170...89,168,962
Ensembl chr10:89,166,890...89,168,965
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Rgs3
regulator of G-protein signaling 3
affects expression
ISO
diethyl malate affects the expression of RGS3 mRNA
CTD
PMID:24814887
NCBI chr 5:78,429,017...78,567,281
Ensembl chr 5:78,428,669...78,567,288
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Runx1t1
RUNX1 partner transcriptional co-repressor 1
affects expression
ISO
diethyl malate affects the expression of RUNX1T1 mRNA
CTD
PMID:24814887
NCBI chr 5:27,284,921...27,440,802
Ensembl chr 5:27,312,928...27,442,841
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Sema3b
semaphorin 3B
affects expression
ISO
diethyl malate affects the expression of SEMA3B mRNA
CTD
PMID:24814887
NCBI chr 8:116,353,791...116,362,655
Ensembl chr 8:116,354,073...116,361,343
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Sema4g
semaphorin 4G
affects expression
ISO
diethyl malate affects the expression of SEMA4G mRNA
CTD
PMID:24814887
NCBI chr 1:264,738,935...264,753,399
Ensembl chr 1:264,741,911...264,753,397
G
Sema5a
semaphorin 5A
affects expression
ISO
diethyl malate affects the expression of SEMA5A mRNA
CTD
PMID:24814887
NCBI chr 2:85,377,318...85,808,970
Ensembl chr 2:85,377,318...85,808,970
G
Stat1
signal transducer and activator of transcription 1
affects expression
ISO
diethyl malate affects the expression of STAT1 mRNA
CTD
PMID:24814887
NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
G
Tgfb2
transforming growth factor, beta 2
affects expression multiple interactions
ISO
diethyl malate affects the expression of TGFB2 mRNA S-ethyl glutathione inhibits the reaction [diethyl malate affects the expression of TGFB2 mRNA]
CTD
PMID:24814887
NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
G
Thbs1
thrombospondin 1
affects expression
ISO
diethyl malate affects the expression of THBS1 mRNA
CTD
PMID:24814887
NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
G
Thbs2
thrombospondin 2
affects expression
ISO
diethyl malate affects the expression of THBS2 mRNA
CTD
PMID:24814887
NCBI chr 1:56,653,929...56,683,571
Ensembl chr 1:56,653,938...56,683,731
G
Tnc
tenascin C
affects expression
ISO
diethyl malate affects the expression of TNC mRNA
CTD
PMID:24814887
NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671
G
Tnfrsf11b
TNF receptor superfamily member 11B
affects expression
ISO
diethyl malate affects the expression of TNFRSF11B mRNA
CTD
PMID:24814887
NCBI chr 7:93,798,580...93,826,586
Ensembl chr 7:93,798,545...93,826,665
G
Tnnt1
troponin T1, slow skeletal type
affects expression
ISO
diethyl malate affects the expression of TNNT1 mRNA
CTD
PMID:24814887
NCBI chr 1:72,889,270...72,899,629
Ensembl chr 1:72,889,270...72,899,659
G
Tslp
thymic stromal lymphopoietin
affects expression
ISO
diethyl malate affects the expression of TSLP mRNA
CTD
PMID:24814887
NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361
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