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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:17alpha-estradiol
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Accession:CHEBI:17160 term browser browse the term
Definition:An estradiol that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17 (the 17alpha stereoisomer).
Synonyms:related_synonym: (17alpha)-estra-1,3,5(10)-triene-3,17-diol;   1,3,5-estratriene-3,17alpha-diol;   13beta-methyl-1,3,5(10)-gonatriene-3,17alpha-diol;   17-epiestradiol;   17alpha-oestradiol;   3,17alpha-dihydroxyestra-1,3,5(10)-triene;   3,17alpha-dihydroxyoestra-1,3,5(10)-triene;   Formula=C18H24O2;   InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17-,18+/m1/s1;   InChIKey=VOXZDWNPVJITMN-SFFUCWETSA-N;   SMILES=[H][C@]12CC[C@]3(C)[C@H](O)CC[C@@]3([H])[C@]1([H])CCc1cc(O)ccc21;   alfatradiol;   alfatradiolum;   alpha-estradiol;   epiestradiol;   epiestrol;   estra-1,3,5(10)-triene-3,17alpha-diol;   estra-1,3,5(10)trien-3,17alpha-diol;   oestra-1,3,5(10)-triene-3,17alpha-diol
 alt_id: CHEBI:14217;   CHEBI:23961;   CHEBI:4862
 xref: Beilstein:2698044;   CAS:57-91-0;   Chemspider:61840;   FooDB:FDB011524;   Gmelin:2190991;   HMDB:HMDB0000429;   KEGG:C02537;   KEGG:D07121;   LINCS:LSM-36371;   LIPID_MAPS_instance:LMST02010029;   MetaCyc:CPD-351;   PMID:10533159;   PMID:10977945;   PMID:11379378;   PMID:11410806;   PMID:12115026;   PMID:12234624;   PMID:15698550;   PMID:15947006;   PMID:16042770;   PMID:1810267;   PMID:18644750;   PMID:19093730;   PMID:1920120;   PMID:20451236;   PMID:22581453;   PMID:24245565;   PMID:24564600;   PMID:28877759;   PMID:7925599;   PMID:9457484;   Wikipedia:17%CE%B1-Estradiol



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17alpha-estradiol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr2 estrogen receptor 2 affects binding EXP 17alpha-estradiol binds to Esr2 protein RGD PMID:9048584 RGD:8694130 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19831
    role 19807
      application 19650
        pharmaceutical 19491
          drug 19491
            protective agent 18205
              geroprotector 17379
                17alpha-estradiol 1
                  17alpha-(N-acetyl-D-glucosaminyl)estradiol 3-glucosiduronic acid 0
                  17alpha-(N-acetyl-alpha-D-glucosaminyl)estradiol 3-glucuronoside 0
                  17alpha-estradiol 17-O-(beta-D-glucuronide) 0
                  17alpha-estradiol 3-glucosiduronic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19831
    subatomic particle 19829
      composite particle 19829
        hadron 19829
          baryon 19829
            nucleon 19829
              atomic nucleus 19829
                atom 19829
                  main group element atom 19779
                    p-block element atom 19779
                      carbon group element atom 19728
                        carbon atom 19724
                          organic molecular entity 19724
                            organic molecule 19677
                              organic cyclic compound 19490
                                organic polycyclic compound 17245
                                  steroid 14689
                                    hydroxy steroid 14434
                                      3-hydroxy steroid 12772
                                        phenolic steroid 11268
                                          estradiol 11264
                                            17alpha-estradiol 1
                                              17alpha-(N-acetyl-D-glucosaminyl)estradiol 3-glucosiduronic acid 0
                                              17alpha-(N-acetyl-alpha-D-glucosaminyl)estradiol 3-glucuronoside 0
                                              17alpha-estradiol 17-O-(beta-D-glucuronide) 0
                                              17alpha-estradiol 3-glucosiduronic acid 0
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