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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:17alpha-estradiol
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Accession:CHEBI:17160 term browser browse the term
Definition:An estradiol that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17 (the 17alpha stereoisomer).
Synonyms:related_synonym: (17alpha)-estra-1,3,5(10)-triene-3,17-diol;   1,3,5-estratriene-3,17alpha-diol;   13beta-methyl-1,3,5(10)-gonatriene-3,17alpha-diol;   17-epiestradiol;   17alpha-oestradiol;   3,17alpha-dihydroxyestra-1,3,5(10)-triene;   3,17alpha-dihydroxyoestra-1,3,5(10)-triene;   Formula=C18H24O2;   InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17-,18+/m1/s1;   InChIKey=VOXZDWNPVJITMN-SFFUCWETSA-N;   SMILES=[H][C@]12CC[C@]3(C)[C@H](O)CC[C@@]3([H])[C@]1([H])CCc1cc(O)ccc21;   alfatradiol;   alfatradiolum;   alpha-estradiol;   epiestradiol;   epiestrol;   estra-1,3,5(10)-triene-3,17alpha-diol;   estra-1,3,5(10)trien-3,17alpha-diol;   oestra-1,3,5(10)-triene-3,17alpha-diol
 alt_id: CHEBI:14217;   CHEBI:23961;   CHEBI:4862
 xref: Beilstein:2698044;   CAS:57-91-0;   Chemspider:61840;   FooDB:FDB011524;   Gmelin:2190991;   HMDB:HMDB0000429;   KEGG:C02537;   KEGG:D07121;   LINCS:LSM-36371;   LIPID_MAPS_instance:LMST02010029;   MetaCyc:CPD-351;   PMID:10533159;   PMID:10977945;   PMID:11379378;   PMID:11410806;   PMID:12115026;   PMID:12234624;   PMID:15698550;   PMID:15947006;   PMID:16042770;   PMID:1810267;   PMID:18644750;   PMID:19093730;   PMID:1920120;   PMID:20451236;   PMID:22581453;   PMID:24245565;   PMID:24564600;   PMID:28877759;   PMID:7925599;   PMID:9457484;   Wikipedia:17%CE%B1-Estradiol


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17alpha-estradiol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr2 estrogen receptor 2 affects binding EXP 17alpha-estradiol binds to Esr2 protein RGD PMID:9048584 RGD:8694130 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20072
    role 20026
      application 19773
        pharmaceutical 19647
          drug 19647
            protective agent 18147
              geroprotector 17287
                17alpha-estradiol 1
                  17alpha-(N-acetyl-D-glucosaminyl)estradiol 3-glucosiduronic acid 0
                  17alpha-(N-acetyl-alpha-D-glucosaminyl)estradiol 3-glucuronoside 0
                  17alpha-estradiol 17-O-(beta-D-glucuronide) 0
                  17alpha-estradiol 3-glucosiduronic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20072
    subatomic particle 20071
      composite particle 20071
        hadron 20071
          baryon 20071
            nucleon 20071
              atomic nucleus 20071
                atom 20071
                  main group element atom 19974
                    p-block element atom 19974
                      carbon group element atom 19903
                        carbon atom 19896
                          organic molecular entity 19896
                            organic molecule 19844
                              organic cyclic compound 19605
                                organic polycyclic compound 17197
                                  steroid 14393
                                    hydroxy steroid 14108
                                      3-hydroxy steroid 12154
                                        phenolic steroid 10575
                                          estradiol 10570
                                            17alpha-estradiol 1
                                              17alpha-(N-acetyl-D-glucosaminyl)estradiol 3-glucosiduronic acid 0
                                              17alpha-(N-acetyl-alpha-D-glucosaminyl)estradiol 3-glucuronoside 0
                                              17alpha-estradiol 17-O-(beta-D-glucuronide) 0
                                              17alpha-estradiol 3-glucosiduronic acid 0
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