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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:17alpha-estradiol
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Accession:CHEBI:17160 term browser browse the term
Definition:An estradiol that is estra-1,3,5(10)-triene substituted by hydroxy groups at positions 3 and 17 (the 17alpha stereoisomer).
Synonyms:related_synonym: (17alpha)-estra-1,3,5(10)-triene-3,17-diol;   1,3,5-estratriene-3,17alpha-diol;   13beta-methyl-1,3,5(10)-gonatriene-3,17alpha-diol;   17-epiestradiol;   17alpha-oestradiol;   3,17alpha-dihydroxyestra-1,3,5(10)-triene;   3,17alpha-dihydroxyoestra-1,3,5(10)-triene;   Formula=C18H24O2;   InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17-,18+/m1/s1;   InChIKey=VOXZDWNPVJITMN-SFFUCWETSA-N;   SMILES=[H][C@]12CC[C@]3(C)[C@H](O)CC[C@@]3([H])[C@]1([H])CCc1cc(O)ccc21;   alfatradiol;   alfatradiolum;   alpha-estradiol;   epiestradiol;   epiestrol;   estra-1,3,5(10)-triene-3,17alpha-diol;   estra-1,3,5(10)trien-3,17alpha-diol;   oestra-1,3,5(10)-triene-3,17alpha-diol
 alt_id: CHEBI:14217;   CHEBI:23961;   CHEBI:4862
 xref: Beilstein:2698044;   CAS:57-91-0;   Chemspider:61840;   FooDB:FDB011524;   Gmelin:2190991;   HMDB:HMDB0000429;   KEGG:C02537;   KEGG:D07121;   LINCS:LSM-36371;   LIPID_MAPS_instance:LMST02010029;   MetaCyc:CPD-351;   PMID:10533159;   PMID:10977945;   PMID:11379378;   PMID:11410806;   PMID:12115026;   PMID:12234624;   PMID:15698550;   PMID:15947006;   PMID:16042770;   PMID:1810267;   PMID:18644750;   PMID:19093730;   PMID:1920120;   PMID:20451236;   PMID:22581453;   PMID:24245565;   PMID:24564600;   PMID:28877759;   PMID:7925599;   PMID:9457484;   Wikipedia:17%CE%B1-Estradiol


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17alpha-estradiol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr2 estrogen receptor 2 affects binding EXP 17alpha-estradiol binds to Esr2 protein RGD PMID:9048584 RGD:8694130 NCBI chr 6:100,589,553...100,645,240
Ensembl chr 6:100,545,206...100,644,709 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20862
    role 20820
      application 20621
        pharmaceutical 20416
          drug 20416
            protective agent 18636
              geroprotector 17747
                17alpha-estradiol 1
                  17alpha-(N-acetyl-D-glucosaminyl)estradiol 3-glucosiduronic acid 0
                  17alpha-(N-acetyl-alpha-D-glucosaminyl)estradiol 3-glucuronoside 0
                  17alpha-estradiol 17-O-(beta-D-glucuronide) 0
                  17alpha-estradiol 3-glucosiduronic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20862
    subatomic particle 20860
      composite particle 20860
        hadron 20860
          baryon 20860
            nucleon 20860
              atomic nucleus 20860
                atom 20860
                  main group element atom 20781
                    p-block element atom 20781
                      carbon group element atom 20715
                        carbon atom 20710
                          organic molecular entity 20710
                            organic molecule 20654
                              organic cyclic compound 20404
                                organic polycyclic compound 17588
                                  steroid 15343
                                    hydroxy steroid 15132
                                      3-hydroxy steroid 13802
                                        phenolic steroid 12626
                                          estradiol 12622
                                            17alpha-estradiol 1
                                              17alpha-(N-acetyl-D-glucosaminyl)estradiol 3-glucosiduronic acid 0
                                              17alpha-(N-acetyl-alpha-D-glucosaminyl)estradiol 3-glucuronoside 0
                                              17alpha-estradiol 17-O-(beta-D-glucuronide) 0
                                              17alpha-estradiol 3-glucosiduronic acid 0
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