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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:paraquat
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Accession:CHEBI:34905 term browser browse the term
Definition:An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions.
Synonyms:exact_synonym: 1,1'-dimethyl-[4,4'-bipyridin]-1,1'-diium
 related_synonym: 1,1'-Dimethyl-4,4'-bipyridinium;   1,1'-dimethyl-4,4'-bipyridyldiylium;   Formula=C12H14N2;   InChI=1S/C12H14N2/c1-13-7-3-11(4-8-13)12-5-9-14(2)10-6-12/h3-10H,1-2H3/q+2;   InChIKey=INFDPOAKFNIJBF-UHFFFAOYSA-N;   N,N'-dimethyl-4,4'-bipyridinium;   N,N'-dimethyl-4,4'-bipyridinium dication;   SMILES=C[n+]1ccc(cc1)-c1cc[n+](C)cc1;   dimethyl viologen;   methyl viologen ion(2+);   paraquat dication;   paraquat ion
 xref: Beilstein:3590305;   CAS:4685-14-7;   Gmelin:51125;   KEGG:C14701
 xref_mesh: MESH:D010269
 xref: PMID:11349957;   PMID:18620719;   PMID:20377249;   PMID:20582739;   PMID:21236547;   PMID:21300143;   PMID:21318114;   PMID:21429624;   PMID:21493003;   PMID:21598522;   PMID:21616728;   PMID:21619794;   PMID:21619822;   PMID:21750730;   PMID:21777615;   PMID:21787677;   PMID:21802509;   PPDB:505;   Reaxys:3590305


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paraquat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aaas aladin WD repeat nucleoporin affects response to substance ISO AAAS protein affects the susceptibility to Paraquat CTD PMID:23315990 NCBI chr 7:143,937,198...143,956,668
Ensembl chr 7:143,937,199...143,956,668
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 increases expression
decreases expression
multiple interactions
ISO Paraquat results in increased expression of ABCA1 mRNA
Paraquat results in decreased expression of ABCA1 protein
TO-901317 inhibits the reaction [Paraquat results in decreased expression of ABCA1 protein]
CTD PMID:27788593, PMID:28480221 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
affects expression
ISO
EXP
[Doxorubicin results in increased expression of ABCB1 protein] which results in decreased susceptibility to Paraquat; ABCB1 protein affects the reaction [Doxorubicin results in decreased susceptibility to Paraquat]; ABCB1 protein results in increased export of and results in decreased susceptibility to Paraquat; valspodar inhibits the reaction [ABCB1 protein results in increased export of Paraquat]
Paraquat affects the expression of ABCB1A mRNA
[ABCB1A gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of HAVCR1 mRNA; [ABCB1A gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of LCN2 mRNA; [ABCB1A gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of NQO1 mRNA; ABCB1A protein results in increased export of and results in decreased susceptibility to Paraquat
CTD PMID:16854511, PMID:23220037, PMID:25015657 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression
multiple interactions
EXP
ISO
Paraquat results in increased expression of ABCB1B mRNA
[ABCB1B gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of HAVCR1 mRNA; [ABCB1B gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of LCN2 mRNA; [ABCB1B gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of NQO1 mRNA; ABCB1B protein results in increased export of and results in decreased susceptibility to Paraquat
CTD PMID:11557130, PMID:15177642, PMID:25015657 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
decreases expression
ISO ABCC1 protein promotes the reaction [cycloartenyl ferulate results in increased transport of and results in decreased abundance of Paraquat]; cycloartenyl ferulate inhibits the reaction [Paraquat results in decreased expression of ABCC1 protein] CTD PMID:26358524 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 affects expression EXP Paraquat affects the expression of ABCC4 mRNA CTD PMID:16854511 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 affects expression EXP Paraquat affects the expression of ABCC9 mRNA CTD PMID:16854511 NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO Paraquat results in increased expression of ABCG2 mRNA CTD PMID:12595580 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Abhd17b abhydrolase domain containing 17B, depalmitoylase increases expression ISO Paraquat results in increased expression of ABHD17B mRNA CTD PMID:21371552 NCBI chr 1:239,266,140...239,301,133
Ensembl chr 1:239,266,921...239,301,176
JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase increases expression ISO Paraquat results in increased expression of ABL1 mRNA CTD PMID:18836921 NCBI chr 3:10,041,820...10,145,076
Ensembl chr 3:10,041,826...10,144,388
JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases phosphorylation
multiple interactions
EXP
ISO
Paraquat results in increased phosphorylation of ACACA protein
PRKAA1 protein affects the reaction [Paraquat results in increased phosphorylation of ACACA protein]
CTD PMID:27324791 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain affects expression EXP Paraquat affects the expression of ACADL mRNA CTD PMID:18198484 NCBI chr 9:73,833,368...73,871,857
Ensembl chr 9:73,833,388...73,871,888
JBrowse link
G Acads acyl-CoA dehydrogenase short chain multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of ACADS mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ACADS mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ACADS mRNA] CTD PMID:23963992 NCBI chr12:47,254,503...47,263,747
Ensembl chr12:47,254,484...47,263,747
JBrowse link
G Acan aggrecan decreases expression ISO Paraquat results in decreased expression of ACAN mRNA CTD PMID:26108578 NCBI chr 1:140,762,758...140,824,441
Ensembl chr 1:140,762,758...140,824,441
JBrowse link
G Ace angiotensin I converting enzyme multiple interactions
decreases expression
decreases activity
affects expression
ISO
EXP
pimagedine inhibits the reaction [Paraquat results in decreased activity of ACE protein]
Paraquat results in decreased expression of ACE mRNA
Paraquat affects the expression of ACE protein
Curcumin inhibits the reaction [Paraquat affects the expression of ACE protein]; Unithiol inhibits the reaction [Paraquat results in decreased expression of ACE mRNA]
CTD PMID:10666014, PMID:12161173, PMID:16182431, PMID:20465954 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 multiple interactions
decreases expression
EXP Unithiol inhibits the reaction [Paraquat results in decreased expression of ACE2 mRNA] CTD PMID:20465954 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Ache acetylcholinesterase multiple interactions
decreases activity
increases expression
ISO
EXP
[LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of ACHE mRNA
Paraquat results in decreased activity of ACHE protein
Paraquat results in increased expression of ACHE mRNA
CTD PMID:23017109, PMID:28916328 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Aco1 aconitase 1 increases activity
decreases expression
decreases activity
ISO
EXP
Paraquat results in increased activity of ACO1 protein
Paraquat results in decreased expression of ACO1 protein
Paraquat results in decreased activity of ACO1 protein
CTD PMID:11520895, PMID:15664434, PMID:17324120, PMID:28542246 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
JBrowse link
G Aco2 aconitase 2 decreases activity
multiple interactions
affects response to substance
ISO
EXP
Paraquat results in decreased activity of ACO2 protein
[GCLM gene mutant form results in increased susceptibility to Paraquat] which results in decreased activity of ACO2 protein; [Paraquat co-treated with Maneb] results in decreased expression of ACO2 mRNA
ACO2 protein affects the susceptibility to Paraquat
ACO2 protein affects the reaction [Paraquat results in increased abundance of Hydrogen Peroxide]; ACO2 protein affects the reaction [Paraquat results in increased abundance of Iron]
SNCA protein inhibits the reaction [Paraquat results in decreased activity of ACO2 protein]
CTD PMID:11520895, PMID:15234109, PMID:18386188, PMID:21517855, PMID:23704229 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Acot7 acyl-CoA thioesterase 7 affects expression EXP Paraquat affects the expression of BACH mRNA CTD PMID:15206577 NCBI chr 5:169,357,582...169,450,215
Ensembl chr 5:169,357,517...169,450,219
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 affects expression
decreases expression
EXP Paraquat affects the expression of ACSL1 mRNA
Paraquat results in decreased expression of ACSL1 mRNA
CTD PMID:15206577, PMID:18198484 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
increases expression
ISO
EXP
CMA1 protein promotes the reaction [Paraquat results in increased expression of ACTA2 protein]; HIF1A protein affects the reaction [Paraquat results in increased expression of ACTA2 protein]
Anthocyanins inhibits the reaction [Paraquat results in increased expression of ACTA2 mRNA]; Anthocyanins inhibits the reaction [Paraquat results in increased expression of ACTA2 protein]; HIF1A protein affects the reaction [Paraquat results in increased expression of ACTA2 protein]; TRAM 34 inhibits the reaction [Paraquat results in increased expression of ACTA2 protein]
Paraquat results in increased expression of ACTA2 mRNA; Paraquat results in increased expression of ACTA2 protein
ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of ACTA2 mRNA]; enterotoxin C, staphylococcal analog inhibits the reaction [Paraquat results in increased expression of ACTA2 mRNA]; Fingolimod Hydrochloride inhibits the reaction [Paraquat results in increased expression of ACTA2 mRNA]; Fingolimod Hydrochloride inhibits the reaction [Paraquat results in increased expression of ACTA2 protein]; pirfenidone inhibits the reaction [Paraquat results in increased expression of ACTA2 mRNA]; plant extract, Puerariae Radix inhibits the reaction [Paraquat results in increased expression of ACTA2 protein]; thymoquinone inhibits the reaction [Paraquat results in increased expression of ACTA2 mRNA]
CTD PMID:17215068, PMID:19969051, PMID:24893116, PMID:25304964, PMID:25873302, PMID:25945502, PMID:26099602, PMID:26758514, PMID:26781174, PMID:26824344, PMID:27375216, PMID:29273418, PMID:30036685, PMID:30403199 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Actb actin, beta increases expression ISO Paraquat results in increased expression of ACTB mRNA CTD PMID:20883675 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841
JBrowse link
G Acvr1 activin A receptor type 1 affects expression
decreases expression
EXP Paraquat affects the expression of ACVR1 mRNA
Paraquat results in decreased expression of ACVR1 mRNA
CTD PMID:15206577, PMID:18198484 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930
JBrowse link
G Acvr2a activin A receptor type 2A decreases expression
affects expression
EXP Paraquat results in decreased expression of ACVR2A mRNA
Paraquat affects the expression of ACVR2A mRNA
CTD PMID:16854511, PMID:18198484 NCBI chr 3:32,947,901...33,034,598
Ensembl chr 3:32,947,378...33,034,282
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 increases expression ISO Paraquat results in increased expression of ADAM17 mRNA; Paraquat results in increased expression of ADAM17 protein CTD PMID:29495171 NCBI chr 6:43,400,525...43,448,280
Ensembl chr 6:43,400,528...43,448,280
JBrowse link
G Adam22 ADAM metallopeptidase domain 22 multiple interactions
increases expression
ISO [Paraquat co-treated with Maneb] affects the expression of ADAM22 mRNA
Paraquat results in increased expression of ADAM22 mRNA
CTD PMID:22563483 NCBI chr 4:22,864,485...23,002,969
Ensembl chr 4:22,859,622...22,996,645
JBrowse link
G Adcy5 adenylate cyclase 5 increases expression EXP Paraquat results in increased expression of ADCY5 mRNA CTD PMID:17077588 NCBI chr11:68,695,839...68,842,452
Ensembl chr11:68,695,839...68,842,320
JBrowse link
G Adcy6 adenylate cyclase 6 increases expression EXP Paraquat results in increased expression of ADCY6 mRNA CTD PMID:18198484 NCBI chr 7:140,270,678...140,291,722
Ensembl chr 7:140,270,692...140,291,620
JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 decreases response to substance ISO ADCYAP1 protein results in decreased susceptibility to Paraquat CTD PMID:23500093 NCBI chr 9:121,705,897...121,725,736
Ensembl chr 9:121,706,979...121,725,716
JBrowse link
G Adgrb1 adhesion G protein-coupled receptor B1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of ADGRB1 mRNA CTD PMID:23017109 NCBI chr 7:115,766,484...115,828,514 JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of ADGRG1 mRNA CTD PMID:18386188 NCBI chr19:10,423,534...10,460,674
Ensembl chr19:10,423,501...10,460,674
JBrowse link
G Adgrl1 adhesion G protein-coupled receptor L1 affects expression EXP Paraquat affects the expression of ADGRL1 mRNA CTD PMID:15493455 NCBI chr19:25,029,037...25,069,146
Ensembl chr19:25,029,037...25,069,142
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]; ADIPOQ protein promotes the reaction [Paraquat results in increased expression of ADIPOR1 mRNA]; ADIPOQ protein promotes the reaction [Paraquat results in increased expression of ADIPOR1 protein]; ADIPOR1 protein promotes the reaction [ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]]
ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of ACTA2 mRNA]; ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA]; ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of MMP9 protein]; ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]; ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of TIMP1 protein]
CTD PMID:25945502 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adipor1 adiponectin receptor 1 multiple interactions
increases expression
ISO ADIPOQ protein promotes the reaction [Paraquat results in increased expression of ADIPOR1 mRNA]; ADIPOQ protein promotes the reaction [Paraquat results in increased expression of ADIPOR1 protein]; ADIPOR1 protein inhibits the reaction [Paraquat results in increased expression of ADIPOR2 mRNA]; ADIPOR1 protein inhibits the reaction [Paraquat results in increased expression of ADIPOR2 protein]; ADIPOR1 protein promotes the reaction [ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]]
Paraquat results in increased expression of ADIPOR1 mRNA; Paraquat results in increased expression of ADIPOR1 protein
CTD PMID:25945502 NCBI chr13:51,240,470...51,260,233
Ensembl chr13:51,240,911...51,260,228
JBrowse link
G Adipor2 adiponectin receptor 2 multiple interactions
increases expression
ISO ADIPOR1 protein inhibits the reaction [Paraquat results in increased expression of ADIPOR2 mRNA]; ADIPOR1 protein inhibits the reaction [Paraquat results in increased expression of ADIPOR2 protein]
Paraquat results in increased expression of ADIPOR2 mRNA; Paraquat results in increased expression of ADIPOR2 protein
CTD PMID:25945502 NCBI chr 4:151,412,135...151,480,108
Ensembl chr 4:151,414,684...151,428,894
JBrowse link
G Adora1 adenosine A1 receptor multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of ADORA1 mRNA CTD PMID:23017109 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852
JBrowse link
G Adora2a adenosine A2a receptor affects expression
increases expression
EXP Paraquat affects the expression of ADORA2A mRNA
Paraquat results in increased expression of ADORA2A mRNA
CTD PMID:16854511, PMID:17077588, PMID:18198484 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Adprh ADP-ribosylarginine hydrolase increases expression ISO Paraquat results in increased expression of ADPRH mRNA CTD PMID:21371552 NCBI chr11:64,861,772...64,868,112
Ensembl chr11:64,861,768...64,868,108
JBrowse link
G Adra1a adrenoceptor alpha 1A decreases expression EXP Paraquat results in decreased expression of ADRA1A mRNA CTD PMID:17077588 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451
JBrowse link
G Adra1d adrenoceptor alpha 1D decreases expression EXP Paraquat results in decreased expression of ADRA1D mRNA CTD PMID:17077588 NCBI chr 3:124,129,558...124,145,566
Ensembl chr 3:124,129,558...124,145,566
JBrowse link
G Ago3 argonaute RISC catalytic component 3 multiple interactions
increases expression
ISO [Paraquat co-treated with Maneb] affects the expression of AGO3 mRNA
Paraquat results in increased expression of AGO3 mRNA
CTD PMID:22563483 NCBI chr 5:144,355,792...144,436,509
Ensembl chr 5:144,364,269...144,436,509
JBrowse link
G Agt angiotensinogen multiple interactions
increases expression
increases secretion
ISO AGT protein modified form promotes the reaction [Paraquat results in increased expression of TGFB1 protein]; CMA1 protein promotes the reaction [Paraquat results in increased expression of AGT protein modified form]
Paraquat results in increased expression of AGT mRNA; Paraquat results in increased expression of AGT protein modified form
Paraquat results in increased secretion of AGT protein
CTD PMID:19969051, PMID:20035857 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression ISO Paraquat results in increased expression of AGTR1 mRNA; Paraquat results in increased expression of AGTR1 protein CTD PMID:20035857 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Agtr2 angiotensin II receptor, type 2 decreases expression ISO Paraquat results in decreased expression of AGTR2 mRNA CTD PMID:20035857 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842
JBrowse link
G Ahnak AHNAK nucleoprotein increases expression ISO Paraquat results in increased expression of AHNAK mRNA CTD PMID:22563483 NCBI chr 1:225,184,883...225,429,638
Ensembl chr 1:225,184,939...225,215,015
JBrowse link
G Ahr aryl hydrocarbon receptor decreases expression ISO Paraquat results in decreased expression of AHR protein CTD PMID:26196221 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of AIF1 protein; [MTHFR gene polymorphism affects the susceptibility to Paraquat] which results in increased expression of AIF1 protein; acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of AIF1 protein] CTD PMID:28202386, PMID:30726997 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions ISO AIFM1 protein inhibits the reaction [Paraquat results in decreased reduction of Glutathione]; AIFM1 protein promotes the reaction [Paraquat results in decreased reduction of Adenine Nucleotides] CTD PMID:15316071 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Ak1 adenylate kinase 1 increases expression ISO Paraquat results in increased expression of AK1 mRNA CTD PMID:21371552 NCBI chr 3:11,652,143...11,659,135 JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of AKR1B3 mRNA CTD PMID:18386188 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of AKR1C3 mRNA CTD PMID:28012437 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression
affects phosphorylation
multiple interactions
ISO Paraquat results in decreased expression of AKT1 mRNA
Paraquat affects the phosphorylation of AKT1 protein
ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of AKT1 protein]
[Maneb co-treated with Paraquat] results in decreased expression of AKT1 mRNA; AKT1 protein affects the reaction [Paraquat results in decreased expression of BCL2 protein]; AKT1 protein affects the reaction [Paraquat results in increased activity of CASP3 protein]; AKT1 protein affects the reaction [Paraquat results in increased expression of BAX protein]; ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of AKT1 protein]; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of AKT1 mRNA]; Paraquat results in increased expression of and results in increased phosphorylation of AKT1 protein; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of AKT1 mRNA]
CTD PMID:16797015, PMID:23898955, PMID:23963992, PMID:28115273, PMID:28428137 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Akt2 AKT serine/threonine kinase 2 multiple interactions
increases response to substance
ISO AKT2 protein affects the reaction [Paraquat results in decreased expression of PPARGC1A protein]; AKT2 protein affects the reaction [Paraquat results in increased expression of NFE2L2 protein]
AKT2 protein results in increased susceptibility to Paraquat
CTD PMID:28115273 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162
JBrowse link
G Alad aminolevulinate dehydratase decreases activity EXP Paraquat results in decreased activity of ALAD protein CTD PMID:12180188 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 multiple interactions
increases activity
EXP alpha-Tocopherol inhibits the reaction [Paraquat results in increased activity of ALAS1 protein] CTD PMID:12180188 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177
JBrowse link
G Alas2 5'-aminolevulinate synthase 2 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of ALAS2 mRNA CTD PMID:22563483 NCBI chr  X:23,167,576...23,187,356
Ensembl chr  X:23,167,696...23,187,341
JBrowse link
G Alb albumin decreases expression EXP Paraquat results in decreased expression of ALB protein CTD PMID:17481832 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression ISO Paraquat results in increased expression of ALDH1A1 mRNA CTD PMID:12595580 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 affects expression EXP Paraquat affects the expression of ALDH1A2 mRNA CTD PMID:15206577 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases expression EXP Paraquat results in decreased expression of ALDH2 mRNA CTD PMID:18198484 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of ALDH5A1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ALDH5A1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ALDH5A1 mRNA] CTD PMID:23963992 NCBI chr17:42,133,076...42,159,413
Ensembl chr17:42,133,076...42,159,413
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of ALDOC mRNA CTD PMID:18386188 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Alkbh8 alkB homolog 8, tRNA methyltransferase increases expression ISO Paraquat results in increased expression of ALKBH8 mRNA CTD PMID:21371552 NCBI chr 6:18,877,885...18,952,773
Ensembl chr 6:18,877,907...18,949,393
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type increases expression ISO Paraquat results in increased expression of ALOX12B mRNA CTD PMID:28012437 NCBI chr10:55,744,646...55,756,524
Ensembl chr10:55,744,588...55,756,566
JBrowse link
G Alox15 arachidonate 15-lipoxygenase multiple interactions
decreases expression
ISO APOD protein affects the reaction [Paraquat results in decreased expression of ALOX15 mRNA]; Paraquat affects the reaction [APOD protein affects the expression of ALOX15 mRNA] CTD PMID:21688324 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161
JBrowse link
G Alox15b arachidonate 15-lipoxygenase, type B increases expression ISO Paraquat results in increased expression of ALOX8 mRNA CTD PMID:28012437 NCBI chr10:55,773,748...55,783,489
Ensembl chr10:55,774,006...55,783,489
JBrowse link
G Alox5 arachidonate 5-lipoxygenase increases expression ISO Paraquat results in increased expression of ALOX5 mRNA CTD PMID:28012437 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303
JBrowse link
G Amn amnion associated transmembrane protein multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of AMN mRNA CTD PMID:22563483 NCBI chr 6:135,724,455...135,731,896
Ensembl chr 6:135,724,455...135,731,896
JBrowse link
G Amph amphiphysin decreases expression EXP Paraquat results in decreased expression of AMPH mRNA CTD PMID:18198484 NCBI chr17:48,304,324...48,562,838
Ensembl chr17:48,304,322...48,562,905
JBrowse link
G Anxa1 annexin A1 increases expression EXP Paraquat results in increased expression of ANXA1 protein CTD PMID:24521700 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012
JBrowse link
G Anxa2 annexin A2 increases expression EXP Paraquat results in increased expression of ANXA2 protein CTD PMID:24521700 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Anxa5 annexin A5 increases expression ISO Paraquat results in increased expression of ANXA5 mRNA CTD PMID:20883675 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Ap3b2 adaptor related protein complex 3 subunit beta 2 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of AP3B2 mRNA CTD PMID:18386188 NCBI chr 1:143,284,041...143,315,846
Ensembl chr 1:143,283,996...143,315,633
JBrowse link
G Ap3d1 adaptor related protein complex 3 subunit delta 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of AP3D1 mRNA CTD PMID:18386188 NCBI chr 7:11,838,639...11,873,992
Ensembl chr 7:11,838,639...11,873,984
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression
affects splicing
increases expression
ISO Paraquat results in decreased expression of APAF1 mRNA
Paraquat affects the splicing of APAF1 exon
Paraquat affects the splicing of APAF1 mRNA
Paraquat results in increased expression of APAF1 mRNA alternative form
CTD PMID:17064354, PMID:23613995, PMID:27111068 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apbb1 amyloid beta precursor protein binding family B member 1 multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of APBB1 mRNA CTD PMID:23017109 NCBI chr 1:170,387,625...170,411,263
Ensembl chr 1:170,387,609...170,404,056
JBrowse link
G Apeh acylaminoacyl-peptide hydrolase decreases response to substance ISO APEH protein results in decreased susceptibility to Paraquat CTD PMID:12727222 NCBI chr 8:116,862,664...116,871,776
Ensembl chr 8:116,862,625...116,872,215
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases response to substance
affects response to substance
ISO APEX1 gene mutant form results in increased susceptibility to Paraquat
APEX1 gene SNP affects the susceptibility to Paraquat
CTD PMID:11454706, PMID:28460087 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO Paraquat affects the expression of and results in increased degradation of APOA1 mRNA CTD PMID:9169468 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875
JBrowse link
G Apod apolipoprotein D multiple interactions
increases expression
decreases response to substance
affects response to substance
ISO Paraquat results in increased uptake of and affects the localization of APOD protein; pyrazolanthrone inhibits the reaction [Paraquat results in increased expression of APOD mRNA]; pyrazolanthrone inhibits the reaction [Paraquat results in increased expression of APOD protein]
APOD protein results in decreased susceptibility to Paraquat
APOD protein affects the susceptibility to Paraquat
[Paraquat co-treated with APOD gene mutant form] results in increased expression of NOS2 mRNA; APOD protein affects the reaction [Paraquat results in decreased expression of ALOX15 mRNA]; APOD protein affects the reaction [Paraquat results in decreased expression of AQR mRNA]; APOD protein affects the reaction [Paraquat results in decreased expression of EPX mRNA]; APOD protein affects the reaction [Paraquat results in decreased expression of GAB1 mRNA]; APOD protein affects the reaction [Paraquat results in decreased expression of GPX2 mRNA]; APOD protein affects the reaction [Paraquat results in decreased expression of IDH1 mRNA]; APOD protein affects the reaction [Paraquat results in decreased expression of LPO mRNA]; APOD protein affects the reaction [Paraquat results in decreased expression of NOS2 mRNA]; APOD protein affects the reaction [Paraquat results in decreased expression of NOX4 mRNA]; APOD protein affects the reaction [Paraquat results in decreased expression of NOXO1 mRNA]; APOD protein affects the reaction [Paraquat results in decreased expression of PTGS1 mRNA]; APOD protein affects the reaction [Paraquat results in increased expression of DUOX1 mRNA]; APOD protein affects the reaction [Paraquat results in increased expression of GDNF mRNA]; APOD protein affects the reaction [Paraquat results in increased expression of GFAP protein]; APOD protein affects the reaction [Paraquat results in increased expression of GPX3 mRNA]; APOD protein affects the reaction [Paraquat results in increased expression of IL19 mRNA]; APOD protein affects the reaction [Paraquat results in increased expression of MPP4 mRNA]; APOD protein affects the reaction [Paraquat results in increased expression of PTGS2 mRNA]; APOD protein affects the reaction [Paraquat results in increased expression of SOD2 mRNA]; APOD protein affects the reaction [Paraquat results in increased expression of SOD3 mRNA]; APOD protein affects the reaction [Paraquat results in increased expression of SRXN1 mRNA]; APOD protein inhibits the reaction [Paraquat results in decreased activity of CTSB protein]; Paraquat affects the reaction [APOD protein affects the expression of ALOX15 mRNA]; Paraquat affects the reaction [APOD protein affects the expression of HMOX1 protein]; Paraquat affects the reaction [APOD protein affects the expression of SOD2 protein]
Paraquat results in increased expression of APOD mRNA; Paraquat results in increased expression of APOD protein
CTD PMID:18419796, PMID:18458334, PMID:21688324, PMID:28182653 NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301
JBrowse link
G App amyloid beta precursor protein increases response to substance
multiple interactions
increases expression
ISO
EXP
APP protein results in increased susceptibility to Paraquat
Estradiol inhibits the reaction [Paraquat results in increased expression of APP protein alternative form]; Estradiol inhibits the reaction [Paraquat results in increased expression of APP protein]
Paraquat results in increased expression of APP protein; Paraquat results in increased expression of APP protein alternative form
Curcumin inhibits the reaction [Paraquat results in increased expression of APP mRNA]; Curcumin inhibits the reaction [Paraquat results in increased expression of APP protein]
Paraquat results in increased expression of APP mRNA; Paraquat results in increased expression of APP protein
CTD PMID:23827522, PMID:27793699, PMID:31715309 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Aprt adenine phosphoribosyl transferase decreases expression ISO Paraquat results in decreased expression of APRT mRNA CTD PMID:21371552 NCBI chr19:55,387,288...55,389,256
Ensembl chr19:55,387,288...55,389,256
JBrowse link
G Aqp1 aquaporin 1 increases expression ISO Paraquat results in increased expression of AQP1 mRNA CTD PMID:12595580 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Aqr aquarius intron-binding spliceosomal factor multiple interactions
decreases expression
ISO APOD protein affects the reaction [Paraquat results in decreased expression of AQR mRNA] CTD PMID:21688324 NCBI chr 3:105,570,399...105,640,431
Ensembl chr 3:105,570,292...105,640,463
JBrowse link
G Arf1 ADP-ribosylation factor 1 affects expression EXP Paraquat affects the expression of ARF1 mRNA CTD PMID:15206577 NCBI chr10:45,562,700...45,579,214
Ensembl chr10:45,563,547...45,579,029
JBrowse link
G Arf3 ADP-ribosylation factor 3 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of ARF3 mRNA CTD PMID:18386188 NCBI chr 7:140,412,463...140,438,751
Ensembl chr 7:140,398,199...140,437,467
JBrowse link
G Arf5 ADP-ribosylation factor 5 increases expression EXP Paraquat results in increased expression of ARF5 mRNA CTD PMID:17077588 NCBI chr 4:55,715,744...55,718,670
Ensembl chr 4:55,715,744...55,718,670
JBrowse link
G Arg1 arginase 1 increases expression
decreases expression
EXP
ISO
Paraquat results in increased expression of ARG1 mRNA
Paraquat results in decreased expression of ARG1 protein
Paraquat results in decreased expression of ARG1 mRNA
CTD PMID:20388547, PMID:24521700, PMID:28467894, PMID:31299241 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Arg2 arginase 2 increases expression EXP Paraquat results in increased expression of ARG2 mRNA CTD PMID:16854511, PMID:20388547 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520
JBrowse link
G Arl2 ADP-ribosylation factor like GTPase 2 decreases expression ISO Paraquat results in decreased expression of ARL2 protein CTD PMID:23807224 NCBI chr 1:221,504,150...221,516,191
Ensembl chr 1:221,504,170...221,516,110
JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 affects response to substance
increases expression
multiple interactions
ISO ARL6IP5 protein affects the susceptibility to Paraquat
Paraquat results in increased expression of ARL6IP5
Paraquat results in increased expression of ARL6IP5 protein
ARL6IP5 protein affects the reaction [Paraquat affects the expression of NFE2L2 protein]; ARL6IP5 protein affects the reaction [Paraquat affects the expression of TH protein]; ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of AKT1 protein]; ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of MAPK1 protein]; ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of MAPK3 protein]
ARL6IP5 protein affects the reaction [Paraquat affects the expression of NFE2L2 protein]; ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of AKT1 protein]; ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of MAPK1 protein]; ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of MAPK3 protein]
CTD PMID:28428137 NCBI chr 4:129,574,363...129,598,240
Ensembl chr 4:129,574,264...129,598,915
JBrowse link
G Arnt2 aryl hydrocarbon receptor nuclear translocator 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of ARNT2 mRNA CTD PMID:23017109 NCBI chr 1:146,399,217...146,556,437
Ensembl chr 1:146,399,217...146,556,171
JBrowse link
G Art3 ADP-ribosyltransferase 3 increases expression ISO Paraquat results in increased expression of ART3 mRNA CTD PMID:12595580 NCBI chr14:17,143,037...17,225,389
Ensembl chr14:17,143,040...17,225,389
JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of ASCL1 mRNA CTD PMID:23017109 NCBI chr 7:28,038,662...28,040,504
Ensembl chr 7:28,038,662...28,040,510
JBrowse link
G Asic1 acid sensing ion channel subunit 1 affects expression
increases expression
EXP Paraquat affects the expression of ASIC1 mRNA
Paraquat results in increased expression of ASIC1 mRNA
CTD PMID:15206577, PMID:17077588, PMID:18198484 NCBI chr 7:141,324,714...141,354,937
Ensembl chr 7:141,326,321...141,354,937
JBrowse link
G Asic3 acid sensing ion channel subunit 3 increases expression EXP Paraquat results in increased expression of ACCN3 mRNA CTD PMID:18198484 NCBI chr 4:7,287,868...7,293,295
Ensembl chr 4:7,288,855...7,292,901
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Paraquat results in increased expression of ATF3 mRNA CTD PMID:12595580 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Paraquat results in increased expression of ATF4 mRNA CTD PMID:21371552 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atf6 activating transcription factor 6 increases expression
increases cleavage
multiple interactions
EXP
ISO
Paraquat results in increased expression of ATF6 protein
Paraquat results in increased cleavage of ATF6 protein
Paraquat results in increased expression of ATF6 protein modified form
Minocycline inhibits the reaction [Paraquat results in increased expression of ATF6 protein]
CTD PMID:22245251, PMID:28986289 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atg12 autophagy related 12 increases expression
multiple interactions
ISO Paraquat results in increased expression of ATG12 protein
Paraquat results in increased expression of ATG12 mRNA
ATG5 protein affects the reaction [Paraquat results in increased expression of [ATG5 protein binds to ATG12 protein]]; Paraquat results in increased expression of [ATG5 protein binds to ATG12 protein]
Maneb promotes the reaction [Paraquat results in increased expression of ATG12 protein]; Paraquat results in increased expression of [ATG5 protein binds to ATG12 protein]
CTD PMID:22292029, PMID:22982048, PMID:27220436 NCBI chr18:40,721,799...40,732,143
Ensembl chr18:40,721,800...40,732,126
JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase increases expression ISO Paraquat results in increased expression of ATG4B mRNA CTD PMID:21371552 NCBI chr 9:100,888,457...100,920,123
Ensembl chr 9:100,888,501...100,918,637
JBrowse link
G Atg5 autophagy related 5 affects response to substance
increases expression
multiple interactions
ISO
EXP
ATG5 protein affects the susceptibility to Paraquat
Paraquat results in increased expression of ATG5 mRNA
[ATG5 protein affects the susceptibility to Paraquat] which affects the abundance of Lipofuscin; ATG5 protein affects the reaction [Paraquat results in increased expression of LAMP1 protein]; Paraquat results in increased expression of [ATG5 protein binds to ATG12 protein]; TLR4 protein affects the reaction [Paraquat results in increased expression of ATG5 protein]
Paraquat results in increased expression of ATG5 mRNA; Paraquat results in increased expression of ATG5 protein
[ATG5 protein affects the susceptibility to Paraquat] which affects the abundance of Lipofuscin; ATG5 protein affects the reaction [Paraquat results in increased expression of [ATG5 protein binds to ATG12 protein]]; ATG5 protein affects the reaction [Paraquat results in increased expression of LAMP1 protein]; ATG5 protein affects the reaction [Paraquat results in increased expression of MAP1LC3A protein]; ATG5 protein promotes the reaction [Paraquat results in increased cleavage of and results in increased activity of CASP3 protein]; Paraquat results in increased expression of [ATG5 protein binds to ATG12 protein]; WNT1 protein inhibits the reaction [Paraquat results in increased expression of ATG5 mRNA]
CTD PMID:22982048, PMID:23997112, PMID:27220436, PMID:27246695, PMID:27324791, PMID:30171970 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G Atg7 autophagy related 7 increases expression
affects response to substance
multiple interactions
ISO Paraquat results in increased expression of ATG7 protein
ATG7 protein affects the susceptibility to Paraquat
Paraquat results in increased expression of ATG7 mRNA
[ATG7 protein affects the susceptibility to Paraquat] which affects the expression of AKR1C3 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of ATM mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BACH1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BARD1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BLM mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BRCA1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BUB1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BUB1B mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CCNA2 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CCNB1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CCNB2 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CCNE1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CCNE2 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDC20 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDC25C mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDK1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDK2 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDKN1A mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CHEK1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of FANCA mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of FANCB mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of FANCD2 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of KIF11 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of KIF14 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of KIF23 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of NBN mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of PLK1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of PLK4 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of PRC1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of SMC1A mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of STAT1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of TRP53 protein; ATG7 protein affects the reaction [Paraquat results in decreased expression of LMNB1 protein]; ATG7 protein affects the reaction [Paraquat results in increased expression of CDKN1A protein]; ATG7 protein affects the reaction [Paraquat results in increased expression of H2AX protein]; ATG7 protein affects the reaction [Paraquat results in increased expression of TRP53 mRNA]; Paraquat affects the reaction [ATG7 protein affects the expression of CDK1 mRNA]; Paraquat affects the reaction [ATG7 protein affects the expression of CDK1 protein]; Paraquat affects the reaction [ATG7 protein affects the expression of LMNB1 mRNA]; TLR4 protein affects the reaction [Paraquat results in increased expression of ATG7 protein]
CTD PMID:27220436, PMID:27246695, PMID:28012437 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
G Atm ATM serine/threonine kinase increases expression
multiple interactions
ISO Paraquat results in increased expression of ATM mRNA
[ATG7 protein affects the susceptibility to Paraquat] which affects the expression of ATM mRNA
CTD PMID:20883675, PMID:28012437 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp13a2 ATPase cation transporting 13A2 multiple interactions
increases response to substance
ISO [ATP13A2 protein results in increased susceptibility to Paraquat] which results in increased abundance of Reactive Oxygen Species CTD PMID:22265822 NCBI chr 5:159,512,208...159,531,631
Ensembl chr 5:159,512,285...159,531,637
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 increases expression EXP Paraquat results in increased expression of ATP1A1 mRNA CTD PMID:16854511 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 affects expression
increases expression
decreases expression
EXP
ISO
Paraquat affects the expression of ATP1A2 mRNA
Paraquat results in increased expression of ATP1A2 mRNA
Paraquat results in decreased expression of ATP1A2 mRNA
CTD PMID:16854511, PMID:17077588, PMID:18198484, PMID:21371552 NCBI chr13:90,651,682...90,676,629
Ensembl chr13:90,651,686...90,676,629
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 affects expression
increases expression
EXP Paraquat affects the expression of ATP1B1 mRNA
Paraquat results in increased expression of ATP1B1 mRNA
CTD PMID:16555045, PMID:16854511 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions
affects expression
increases expression
ISO
EXP
IGF1 gene mutant form inhibits the reaction [Paraquat results in increased expression of ATP2A2 protein]
Paraquat affects the expression of ATP2A2 mRNA
CTD PMID:16854511, PMID:17979500 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326
JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 decreases expression EXP Paraquat results in decreased expression of ATP2B2 mRNA CTD PMID:18198484 NCBI chr 4:145,704,779...145,948,997
Ensembl chr 4:145,703,046...146,016,325
JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of ATP5A1 protein; Minocycline inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ATP5A1 protein]; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ATP5A1 protein] CTD PMID:23562983 NCBI chr18:74,156,553...74,164,490
Ensembl chr18:74,156,553...74,164,495
JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of ATP5G1 mRNA CTD PMID:18386188 NCBI chr10:83,895,941...83,898,640
Ensembl chr10:83,895,947...83,898,527
JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 multiple interactions ISO ATP6V0A1 protein affects the reaction [Paraquat results in increased expression of MAP1LC3A protein] CTD PMID:22982048 NCBI chr10:88,914,264...88,967,736
Ensembl chr10:88,914,276...88,967,748
JBrowse link
G Atp6v0b ATPase H+ transporting V0 subunit B multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of ATP6V0B mRNA CTD PMID:18386188 NCBI chr 5:136,718,352...136,719,868
Ensembl chr 5:136,718,352...136,721,379
JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of ATP6V0C mRNA CTD PMID:18386188 NCBI chr10:13,537,031...13,543,407
Ensembl chr10:13,537,033...13,542,077
JBrowse link
G Atp6v0e2 ATPase, H+ transporting V0 subunit e2 increases expression ISO Paraquat results in increased expression of ATP6V0E2 mRNA CTD PMID:21371552 NCBI chr 4:78,168,117...78,171,265
Ensembl chr 4:78,168,117...78,171,265
JBrowse link
G Atp6v1c1 ATPase H+ transporting V1 subunit C1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of ATP6V1C1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ATP6V1C1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ATP6V1C1 mRNA] CTD PMID:23963992 NCBI chr 7:77,678,853...77,716,658
Ensembl chr 7:77,678,968...77,716,408
JBrowse link
G Atp7a ATPase copper transporting alpha multiple interactions
increases response to substance
ISO ATP7A protein promotes the reaction [Paraquat results in increased chemical synthesis of Hydrogen Peroxide]
ATP7A protein results in increased susceptibility to Paraquat
CTD PMID:29058724 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644
JBrowse link
G Atp8a2 ATPase phospholipid transporting 8A2 multiple interactions
increases expression
ISO [Paraquat co-treated with Maneb] affects the expression of ATP8A2 mRNA
Paraquat results in increased expression of ATP8A2 mRNA
CTD PMID:22563483 NCBI chr15:39,955,689...40,488,737
Ensembl chr15:40,000,322...40,428,800
JBrowse link
G Atxn1 ataxin 1 affects expression EXP Paraquat affects the expression of ATXN1 mRNA CTD PMID:15206577 NCBI chr17:19,160,986...19,533,814
Ensembl chr17:19,249,952...19,533,814
JBrowse link
G Atxn2 ataxin 2 affects splicing ISO Paraquat affects the splicing of ATXN2 exon CTD PMID:27111068 NCBI chr12:40,264,601...40,335,637
Ensembl chr12:40,266,662...40,332,612
JBrowse link
G Aurka aurora kinase A affects expression ISO Paraquat affects the expression of AURKA mRNA CTD PMID:26345256 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210
JBrowse link
G Avpr1b arginine vasopressin receptor 1B decreases expression EXP Paraquat results in decreased expression of AVPR1B mRNA CTD PMID:17077588 NCBI chr13:48,367,307...48,378,831
Ensembl chr13:48,367,307...48,378,831
JBrowse link
G Avpr2 arginine vasopressin receptor 2 decreases expression EXP Paraquat results in decreased expression of AVPR2 mRNA CTD PMID:18198484 NCBI chr  X:156,889,006...156,892,707
Ensembl chr  X:156,889,410...156,891,213
JBrowse link
G Axin1 axin 1 decreases expression
multiple interactions
ISO Paraquat results in decreased expression of AXIN1 mRNA; Paraquat results in decreased expression of AXIN1 protein
WNT1 protein inhibits the reaction [Paraquat results in decreased expression of AXIN1 mRNA]
CTD PMID:30171970
G Axin2 axin 2 decreases expression ISO Paraquat results in decreased expression of AXIN2 mRNA CTD PMID:27788593 NCBI chr10:97,212,483...97,238,824
Ensembl chr10:97,212,432...97,239,642
JBrowse link
G Bach1 BTB domain and CNC homolog 1 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BACH1 mRNA CTD PMID:28012437 NCBI chr11:27,364,913...27,398,713
Ensembl chr11:27,364,916...27,398,842
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions
increases expression
decreases expression
ISO
EXP
[Paraquat co-treated with Maneb] results in increased phosphorylation of BAD protein
TLR4 gene mutant form inhibits the reaction [Paraquat results in increased expression of BAD protein]
Paraquat results in decreased expression of BAD mRNA
Paraquat results in increased expression of BAD mRNA
CTD PMID:15824117, PMID:17935786, PMID:18836921, PMID:27442881 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453
JBrowse link
G Bag1 BAG cochaperone 1 increases expression ISO Paraquat results in increased expression of BAG1 mRNA CTD PMID:18836921 NCBI chr 5:57,254,421...57,267,002
Ensembl chr 5:57,254,421...57,267,002
JBrowse link
G Bag4 BAG cochaperone 4 increases expression ISO Paraquat results in increased expression of BAG4 mRNA CTD PMID:18836921 NCBI chr16:71,057,709...71,075,874
Ensembl chr16:71,058,022...71,075,320
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression
multiple interactions
affects response to substance
decreases expression
ISO
EXP
Paraquat results in increased expression of BAK1 mRNA; Paraquat results in increased expression of BAK1 protein
[Paraquat co-treated with Maneb] results in increased expression of BAK1 protein; LGK974 inhibits the reaction [Paraquat results in increased expression of BAK1 protein]; Maneb inhibits the reaction [BAK1 protein affects the susceptibility to Paraquat]; Paraquat inhibits the reaction [BAK1 protein affects the susceptibility to Maneb]
[Maneb co-treated with Paraquat] results in increased expression of BAK1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of BAK1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of BAK1 mRNA]
Paraquat results in decreased expression of BAK1 mRNA
NFE2L2 mutant form inhibits the reaction [Paraquat results in increased expression of BAK1 mRNA]; Paraquat promotes the reaction [BAX protein binds to BAK1 protein]
CTD PMID:18056701, PMID:18266926, PMID:18836921, PMID:22230393, PMID:22678742, PMID:23963992, PMID:25947082, PMID:30205152 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bard1 BRCA1 associated RING domain 1 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BARD1 mRNA CTD PMID:28012437 NCBI chr 9:78,297,723...78,368,777
Ensembl chr 9:78,294,834...78,369,031
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
affects expression
increases expression
decreases expression
ISO
EXP
[Maneb co-treated with Paraquat] results in increased expression of BAX mRNA; [Paraquat co-treated with Maneb] results in increased expression of BAX protein; AKT1 protein affects the reaction [Paraquat results in increased expression of BAX protein]; GPX1 protein affects the reaction [Paraquat affects the expression of BAX mRNA]; Lithium Chloride inhibits the reaction [Paraquat results in increased expression of BAX protein]; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of BAX protein]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of BAX mRNA]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of BAX protein]; Silymarin inhibits the reaction [Paraquat results in increased expression of BAX protein]; TO-901317 inhibits the reaction [Paraquat results in increased expression of BAX protein]
Paraquat results in increased expression of BAX mRNA; Paraquat results in increased expression of BAX protein
[Paraquat co-treated with Maneb] results in increased expression of BAX protein; BAX protein affects the susceptibility to [Paraquat co-treated with Maneb]; Curcumin inhibits the reaction [Paraquat results in increased expression of BAX protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Paraquat results in increased expression of BAX protein]; salvin inhibits the reaction [Paraquat results in increased expression of BAX protein]; WNT1 protein inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; WNT1 protein inhibits the reaction [Paraquat results in increased expression of BAX protein]
Paraquat results in decreased expression of BAX mRNA
[Paraquat co-treated with Decitabine] results in increased expression of BAX protein; Anthocyanins inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; Anthocyanins inhibits the reaction [Paraquat results in increased expression of BAX protein]; Docosahexaenoic Acids inhibits the reaction [Paraquat results in increased expression of BAX protein]; NFE2L2 mutant form inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; Paraquat promotes the reaction [BAX protein binds to BAK1 protein]; Paraquat results in increased expression of and affects the localization of BAX protein
CTD PMID:12654481, PMID:12714668, PMID:15206577, PMID:15824117, PMID:18253895, PMID:18266926, PMID:18836921, PMID:20964710, PMID:22678742, PMID:22796470, PMID:23963992, PMID:25947082, PMID:26468117, PMID:26686574, PMID:26887261, PMID:27220436, PMID:27442881, PMID:27793699, PMID:28115273, PMID:28480221, PMID:29054699, PMID:30171970, PMID:30185695, PMID:30403199 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Paraquat results in increased expression of BBC3 protein CTD PMID:18266926 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bche butyrylcholinesterase decreases activity ISO Paraquat results in decreased activity of BCHE protein CTD PMID:17364237 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta increases expression ISO Paraquat results in increased expression of BCKDHB mRNA CTD PMID:21371552 NCBI chr 8:91,464,229...91,656,134
Ensembl chr 8:91,464,229...91,656,134
JBrowse link
G Bcl10 BCL10, immune signaling adaptor decreases expression ISO Paraquat results in decreased expression of BCL10 mRNA CTD PMID:18836921 NCBI chr 2:251,805,392...251,814,957
Ensembl chr 2:251,805,392...251,814,957
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
decreases response to substance
increases expression
ISO
EXP
[Maneb co-treated with Paraquat] results in decreased expression of BCL2 mRNA; AKT1 protein affects the reaction [Paraquat results in decreased expression of BCL2 protein]; GPX1 protein affects the reaction [Paraquat affects the expression of BCL2 mRNA]; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of BCL2 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of BCL2 mRNA]; Silymarin inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; TO-901317 inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]
Paraquat results in decreased expression of BCL2 mRNA; Paraquat results in decreased expression of BCL2 protein
Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; salvin inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]
BCL2 protein results in decreased susceptibility to Paraquat
Paraquat results in increased expression of BCL2 mRNA
[Paraquat co-treated with Decitabine] results in decreased expression of BCL2 protein; Anthocyanins inhibits the reaction [Paraquat results in decreased expression of BCL2 mRNA]; Anthocyanins inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; Docosahexaenoic Acids inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; NFE2L2 mutant form inhibits the reaction [Paraquat results in decreased expression of BCL2 mRNA]
CTD PMID:12654481, PMID:12714668, PMID:15475374, PMID:18836921, PMID:22230393, PMID:22678742, PMID:22796470, PMID:23963992, PMID:26468117, PMID:26686574, PMID:26887261, PMID:27220436, PMID:28115273, PMID:28480221, PMID:29054699, PMID:30171970, PMID:30185695, PMID:30403199, PMID:30698896, PMID:31400064 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2a1 BCL2-related protein A1 decreases expression
multiple interactions
increases expression
ISO Paraquat results in decreased expression of BCL2A1 mRNA
[Paraquat co-treated with Maneb] results in increased expression of BCL2A1 protein
Paraquat results in increased expression of BCL2A1 mRNA; Paraquat results in increased expression of BCL2A1 protein
CTD PMID:18056701, PMID:18266926, PMID:18836921 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
increases expression
decreases expression
affects expression
decreases response to substance
ISO
EXP
[Paraquat co-treated with Maneb] results in decreased expression of BCL2L1 protein
Paraquat results in increased expression of BCL2L1 mRNA; Paraquat results in increased expression of BCL2L1 protein
Paraquat results in decreased expression of BCL2L1 mRNA
Paraquat affects the expression of BCL2L1 mRNA
BCL2L1 gene mutant form results in decreased susceptibility to Paraquat
GPX1 protein affects the reaction [Paraquat results in increased expression of BCL2L1 protein]
CTD PMID:10970895, PMID:12595580, PMID:12654481, PMID:15824117, PMID:16797015, PMID:16854511, PMID:18056701, PMID:18836921 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l10 BCL2 like 10 decreases expression ISO Paraquat results in decreased expression of BCL2L10 mRNA CTD PMID:18836921 NCBI chr 8:82,288,705...82,294,750
Ensembl chr 8:82,288,705...82,294,744
JBrowse link
G Bcl2l11 BCL2 like 11 decreases expression
multiple interactions
increases expression
ISO Paraquat results in decreased expression of BCL2L11 mRNA
[Paraquat co-treated with Maneb] results in increased expression of BCL2L11 protein
Paraquat results in increased expression of BCL2L11 protein
Paraquat results in increased expression of BCL2L11 mRNA
FOXO3 mutant form inhibits the reaction [Paraquat results in increased expression of BCL2L11 mRNA]
CTD PMID:18266926, PMID:18836921, PMID:23620592 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bcl2l2 Bcl2-like 2 multiple interactions ISO GPX1 protein affects the reaction [Paraquat affects the expression of BCL2L2 mRNA] CTD PMID:12654481 NCBI chr15:33,543,774...33,549,165
Ensembl chr15:33,544,312...33,549,164
JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 decreases expression ISO Paraquat results in decreased expression of BCLAF1 mRNA CTD PMID:18836921 NCBI chr 1:15,799,753...15,828,838
Ensembl chr 1:15,782,477...15,860,624
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases expression
ISO
EXP
[Maneb co-treated with Paraquat] results in decreased expression of BDNF mRNA
Paraquat results in increased expression of BDNF mRNA
[Paraquat co-treated with Maneb] results in decreased expression of BDNF mRNA; [Paraquat co-treated with Maneb] results in decreased expression of BDNF protein
CTD PMID:23017109, PMID:27460631, PMID:29454966 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 multiple interactions
increases expression
ISO [Paraquat co-treated with MAP3K5 protein] results in increased expression of BECN1 protein; salubrinal promotes the reaction [[Paraquat co-treated with MAP3K5 protein] results in increased expression of BECN1 protein]; WNT1 protein inhibits the reaction [Paraquat results in increased expression of BECN1 mRNA]
Paraquat results in increased expression of BECN1 mRNA; Paraquat results in increased expression of BECN1 protein
CTD PMID:20929985, PMID:22292029, PMID:25092649, PMID:27220436, PMID:30171970 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bfar bifunctional apoptosis regulator increases expression ISO Paraquat results in increased expression of BFAR mRNA CTD PMID:18836921 NCBI chr10:1,464,658...1,471,152
NCBI chr10:1,464,783...1,497,653
Ensembl chr10:1,464,765...1,497,653
JBrowse link
G Bicd1 BICD cargo adaptor 1 increases expression
multiple interactions
ISO Paraquat results in increased expression of BICD1 mRNA
[Paraquat co-treated with Maneb] affects the expression of BICD1 mRNA
CTD PMID:22563483 NCBI chr 4:184,018,845...184,167,628
Ensembl chr 4:184,019,087...184,165,540
JBrowse link
G Bid BH3 interacting domain death agonist decreases expression
multiple interactions
increases expression
increases cleavage
ISO Paraquat results in decreased expression of BID mRNA
[Maneb co-treated with Paraquat] results in increased expression of BID protein
Paraquat results in increased expression of BID mRNA; Paraquat results in increased expression of BID protein
Paraquat results in increased cleavage of BID protein
CTD PMID:18056701, PMID:18266926, PMID:18836921, PMID:28414160 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Bik BCL2-interacting killer increases expression
multiple interactions
ISO Paraquat results in increased expression of BIK mRNA
[Paraquat co-treated with Maneb] results in increased expression of BIK protein
CTD PMID:18266926, PMID:18836921 NCBI chr 7:124,390,924...124,410,449
Ensembl chr 7:124,391,432...124,410,447
JBrowse link
G Bin1 bridging integrator 1 affects splicing ISO Paraquat affects the splicing of BIN1 mRNA CTD PMID:23613995 NCBI chr18:25,163,575...25,222,139
Ensembl chr18:25,163,561...25,222,135
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO Paraquat results in decreased expression of BIRC2 mRNA CTD PMID:18836921 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO Paraquat results in decreased expression of BIRC3 mRNA CTD PMID:18836921 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression
decreases expression
ISO
EXP
Paraquat results in increased expression of BIRC5 mRNA
Paraquat results in decreased expression of BIRC5 mRNA
CTD PMID:26345256, PMID:26887261 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Blm BLM RecQ like helicase multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BLM mRNA CTD PMID:28012437 NCBI chr 1:142,246,773...142,332,616
Ensembl chr 1:142,246,790...142,332,588
JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of BMP2 mRNA CTD PMID:23017109 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bmp4 bone morphogenetic protein 4 multiple interactions
decreases expression
ISO
EXP
[LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of BMP4 mRNA; [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of BMP4 mRNA
Paraquat results in decreased expression of BMP4 mRNA
CTD PMID:18198484, PMID:23017109 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bnip1 BCL2 interacting protein 1 decreases expression ISO Paraquat results in decreased expression of BNIP1 mRNA CTD PMID:18836921 NCBI chr10:16,677,077...16,689,321
Ensembl chr10:16,677,077...16,689,321
JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression
affects response to substance
increases expression
ISO Paraquat results in decreased expression of BNIP3 mRNA
BNIP3 protein affects the susceptibility to Paraquat
Paraquat results in increased expression of BNIP3 protein
Paraquat results in increased expression of BNIP3 mRNA; Paraquat results in increased expression of BNIP3 protein
CTD PMID:18056701, PMID:18266926, PMID:18836921, PMID:23315990 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO Paraquat results in increased expression of BNIP3L mRNA CTD PMID:18836921 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G Bop1 BOP1 ribosomal biogenesis factor increases expression ISO Paraquat results in increased expression of BOP1 mRNA CTD PMID:21371552 NCBI chr 7:117,514,529...117,538,342
Ensembl chr 7:117,514,533...117,538,342
JBrowse link
G Brca1 BRCA1, DNA repair associated decreases response to substance
multiple interactions
ISO BRCA1 protein results in decreased susceptibility to Paraquat
[ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BRCA1 mRNA
CTD PMID:15520196, PMID:28012437 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Brca2 BRCA2, DNA repair associated decreases expression ISO Paraquat results in decreased expression of BRCA2 mRNA CTD PMID:28012437 NCBI chr12:503,660...544,754
Ensembl chr12:504,007...544,748
JBrowse link
G Brf1 BRF1, RNA polymerase III transcription initiation factor subunit multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of BRF1 mRNA CTD PMID:18386188 NCBI chr 6:137,762,230...137,808,573
Ensembl chr 6:137,765,122...137,808,303
JBrowse link
G Bsg basigin (Ok blood group) increases expression ISO Paraquat results in increased expression of BSG protein CTD PMID:29287252 NCBI chr 7:12,875,536...12,882,753
Ensembl chr 7:12,875,537...12,882,753
JBrowse link
G Bst1 bone marrow stromal cell antigen 1 increases expression EXP Paraquat results in increased expression of BST1 mRNA CTD PMID:18198484 NCBI chr14:71,798,218...71,814,540
Ensembl chr14:71,798,651...71,814,523
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Paraquat results in increased expression of BTG2 mRNA CTD PMID:12595580 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BUB1 mRNA CTD PMID:28012437 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BUB1B mRNA CTD PMID:28012437 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G Ca3 carbonic anhydrase 3 affects expression EXP Paraquat affects the expression of CAR3 mRNA CTD PMID:15206577 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C increases expression EXP Paraquat results in increased expression of CACNA1C mRNA CTD PMID:18198484 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913
JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E multiple interactions
increases expression
ISO [Paraquat co-treated with Maneb] affects the expression of CACNA1E mRNA
Paraquat results in increased expression of CACNA1E mRNA
CTD PMID:22563483 NCBI chr13:71,899,445...72,534,992
Ensembl chr13:71,906,702...72,367,980
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 increases expression EXP Paraquat results in increased expression of CACNB3 mRNA CTD PMID:18198484 NCBI chr 7:140,311,120...140,324,902
Ensembl chr 7:140,315,368...140,324,902
JBrowse link
G Cacybp calcyclin binding protein multiple interactions
increases expression
ISO [Paraquat co-treated with Maneb] results in increased expression of CACYBP mRNA
Paraquat results in increased expression of CACYBP mRNA
CTD PMID:18386188, PMID:28619522 NCBI chr13:77,948,771...77,959,089
Ensembl chr13:77,948,771...77,959,110
JBrowse link
G Calcr calcitonin receptor decreases expression EXP Paraquat results in decreased expression of CALCR mRNA CTD PMID:17077588 NCBI chr 4:28,627,439...28,702,559
Ensembl chr 4:28,627,442...28,702,559
JBrowse link
G Calm1 calmodulin 1 multiple interactions
increases expression
ISO [Maneb co-treated with Paraquat] results in increased expression of CALM1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CALM1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CALM1 mRNA]
Paraquat results in increased expression of CALM1 mRNA
CTD PMID:23963992, PMID:31368498 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292
JBrowse link
G Calm2 calmodulin 2 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of CALM2 mRNA CTD PMID:18386188 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968
JBrowse link
G Camp cathelicidin antimicrobial peptide multiple interactions ISO
EXP
[Paraquat co-treated with Maneb] affects the expression of CAMP mRNA
[Paraquat co-treated with Maneb] results in decreased expression of CAMP mRNA
CTD PMID:22563483, PMID:27460631 NCBI chr 8:117,930,557...117,932,371
Ensembl chr 8:117,930,546...117,932,518
JBrowse link
G Capn1 calpain 1 multiple interactions
increases activity
EXP
ISO
Paraquat results in increased expression of and results in increased activity of CAPN1 protein
calpeptin inhibits the reaction [Paraquat results in increased activity of CAPN1 protein]
CTD PMID:22678742, PMID:24509835 NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322
JBrowse link
G Capn11 calpain 11 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of CAPN11 mRNA CTD PMID:22563483 NCBI chr 9:17,728,845...17,750,357
Ensembl chr 9:17,728,816...17,750,363
JBrowse link
G Capn2 calpain 2 multiple interactions EXP Paraquat results in increased expression of and results in increased activity of CAPN2 protein CTD PMID:22678742 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811
JBrowse link
G Capn6 calpain 6 increases expression ISO Paraquat results in increased expression of CAPN6 mRNA CTD PMID:26345256 NCBI chr  X:115,049,113...115,073,824
Ensembl chr  X:115,049,154...115,073,890
JBrowse link
G Car2 carbonic anhydrase 2 increases expression EXP Paraquat results in increased expression of CAR2 protein CTD PMID:24521700 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Card6 caspase recruitment domain family, member 6 decreases expression ISO Paraquat results in decreased expression of CARD6 mRNA CTD PMID:18836921 NCBI chr 2:54,810,676...54,824,050
Ensembl chr 2:54,810,110...54,824,033
JBrowse link
G Casp1 caspase 1 multiple interactions
increases expression
decreases activity
EXP
ISO
Glyburide inhibits the reaction [Paraquat results in increased expression of CASP1 protein]; Sodium Salicylate inhibits the reaction [Paraquat results in decreased activity of CASP1 protein]
Paraquat results in increased expression of CASP1 protein; Paraquat results in increased expression of CASP1 protein modified form
Paraquat results in increased expression of CASP1 mRNA; Paraquat results in increased expression of CASP1 protein
[Maneb co-treated with Paraquat] results in increased expression of CASP1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CASP1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CASP1 mRNA]; Silymarin inhibits the reaction [Paraquat results in increased expression of CASP1 protein modified form]; Silymarin inhibits the reaction [Paraquat results in increased expression of CASP1 protein]
CTD PMID:17561093, PMID:18836921, PMID:23963992, PMID:25338942, PMID:29054699 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp12 caspase 12 multiple interactions
increases activity
increases expression
increases degradation
EXP Minocycline results in decreased degradation of [Paraquat results in increased expression of CASP12 protein]; NFE2L2 mutant form inhibits the reaction [Paraquat results in increased expression of CASP12 mRNA]
Paraquat results in increased activity of CASP12 protein
Paraquat results in increased expression of CASP12 mRNA; Paraquat results in increased expression of CASP12 protein
Paraquat results in increased degradation of CASP12 protein
CTD PMID:22245251, PMID:22678742, PMID:24912633 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160
JBrowse link
G Casp2 caspase 2 decreases expression ISO Paraquat results in decreased expression of CASP2 mRNA CTD PMID:18836921 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
decreases expression
increases cleavage
ISO
EXP
AKT1 protein affects the reaction [Paraquat results in increased activity of CASP3 protein]; GPX1 protein affects the reaction [Paraquat results in increased activity of CASP3 protein]; GPX1 protein affects the reaction [Paraquat results in increased expression of CASP3 protein]; PARK7 protein affects the reaction [Paraquat results in increased cleavage of CASP3 protein]; Silymarin inhibits the reaction [Paraquat results in increased expression of CASP3 protein modified form]
Paraquat results in decreased expression of CASP3 mRNA
Paraquat results in increased expression of CASP3 mRNA; Paraquat results in increased expression of CASP3 protein; Paraquat results in increased expression of CASP3 protein modified form
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin inhibits the reaction [Paraquat results in increased activity of CASP3 protein]]; 3-methyladenine promotes the reaction [Paraquat results in increased activity of CASP3 protein]; [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of CASP3 mRNA]; [PTGDS protein results in decreased susceptibility to Paraquat] which results in decreased cleavage of CASP3 protein; Acetylcysteine inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; ATG5 protein promotes the reaction [Paraquat results in increased cleavage of and results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; GHRL protein inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; LGK974 inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; Paraquat promotes the reaction [Trientine results in increased activity of CASP3 protein]; Paraquat results in increased cleavage of and results in increased activity of CASP3 protein; PRKN protein inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; PTGDS mutant form promotes the reaction [Paraquat results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [Paraquat results in increased expression of CASP3 protein modified form]; salubrinal inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; salvin inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; TLR9 protein promotes the reaction [Paraquat results in increased expression of CASP3 protein modified form]
Acetylcysteine inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]; calpeptin inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]; Cyclosporine inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]; Dibucaine inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]; diphenyleneiodonium inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]; Edaravone inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]; epigallocatechin gallate inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; Minocycline inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]; NFE2L2 mutant form inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; Sodium Salicylate inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; U 74389F inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]
CTD PMID:11369509, PMID:12654481, PMID:16310883, PMID:17018646, PMID:17215068, PMID:17324951, PMID:17341480, PMID:17561093, PMID:17936647, PMID:18056701, PMID:18253895, PMID:18836921, PMID:19735704, PMID:20929985, PMID:21300143, PMID:21777615, PMID:22043816, PMID:22245251, PMID:22678742, PMID:22736252, PMID:22987761, PMID:23807224, PMID:23997112, PMID:24060684, PMID:24130211, PMID:24866057, PMID:24912633, PMID:25947082, PMID:26468117, PMID:26686574, PMID:27442881, PMID:28115273, PMID:28363843, PMID:28414160, PMID:28428137, PMID:28474156, PMID:28986289, PMID:29054699, PMID:30144575, PMID:30185695, PMID:30205152, PMID:30698896, PMID:30967525, PMID:31381934, PMID:31400064 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 increases activity
multiple interactions
increases expression
EXP
ISO
Paraquat results in increased activity of CASP7 protein
CAT protein inhibits the reaction [Paraquat results in increased activity of CASP7 protein]
Paraquat results in increased expression of CASP7 mRNA
NFE2L2 mutant form inhibits the reaction [Paraquat results in increased activity of CASP7 protein]
CTD PMID:17324951, PMID:18836921, PMID:22678742, PMID:24866057 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 increases expression
increases cleavage
multiple interactions
decreases expression
increases activity
ISO
EXP
Paraquat results in increased expression of CASP8 mRNA; Paraquat results in increased expression of CASP8 mRNA alternative form
Paraquat results in increased cleavage of CASP8 protein
6-bromoindirubin-3'-oxime promotes the reaction [Paraquat results in increased expression of CASP8 protein modified form]; Paraquat promotes the reaction [TNFRSF10B protein binds to CASP8 protein]
Paraquat results in decreased expression of CASP8 mRNA
Paraquat results in increased activity of CASP8 protein
Sodium Salicylate inhibits the reaction [Paraquat results in increased activity of CASP8 protein]
CTD PMID:17064354, PMID:17561093, PMID:20883675, PMID:24912633, PMID:26468117, PMID:28414160 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions
increases activity
decreases expression
increases cleavage
ISO
EXP
Paraquat results in increased expression of CASP9 mRNA; Paraquat results in increased expression of CASP9 mRNA alternative form; Paraquat results in increased expression of CASP9 protein
Paraquat results in increased expression of CASP9 protein modified form
[Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of CASP9 mRNA]; [PTGDS protein results in decreased susceptibility to Paraquat] which results in decreased cleavage of CASP9 protein; PRKN protein inhibits the reaction [Paraquat results in increased activity of CASP9 protein]; PTGDS mutant form promotes the reaction [Paraquat results in increased cleavage of CASP9 protein]; salvin inhibits the reaction [Paraquat results in increased activity of CASP9 protein]
Paraquat results in decreased expression of CASP9 mRNA
[Maneb co-treated with Paraquat] results in increased expression of CASP9 mRNA; [Paraquat co-treated with Maneb] results in increased expression of CASP9 protein; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CASP9 mRNA]; Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CASP9 protein]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CASP9 mRNA]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CASP9 protein]
CTD PMID:17064354, PMID:18253895, PMID:18836921, PMID:20964710, PMID:22043816, PMID:22736252, PMID:23963992, PMID:24912633, PMID:26649146, PMID:26686574, PMID:27442881, PMID:30144575, PMID:30698896, PMID:31400064 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase affects response to substance
decreases expression
affects activity
decreases activity
increases expression
increases activity
multiple interactions
decreases response to substance
increases response to substance
ISO
EXP
CAT protein affects the susceptibility to Paraquat
Paraquat results in decreased expression of CAT protein
Paraquat affects the activity of CAT protein
Paraquat results in decreased activity of CAT protein
Paraquat results in increased expression of CAT mRNA; Paraquat results in increased expression of CAT protein
Paraquat results in increased activity of CAT protein
[Maneb co-treated with Paraquat] results in increased expression of CAT mRNA; [Mifepristone co-treated with Paraquat] results in decreased activity of CAT protein; [Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased expression of CAT mRNA; [Prednisolone co-treated with pirfenidone] inhibits the reaction [Paraquat results in decreased activity of CAT protein]; betanin inhibits the reaction [Paraquat results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Paraquat results in decreased activity of CAT protein]; embelin inhibits the reaction [Paraquat results in decreased expression of CAT protein]; NFE2L2 protein inhibits the reaction [[Mifepristone co-treated with Paraquat] results in decreased activity of CAT protein]; Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of CAT protein]; pirfenidone inhibits the reaction [Paraquat results in decreased activity of CAT protein]; Plant Extracts inhibits the reaction [Paraquat results in increased activity of CAT protein]; Unithiol promotes the reaction [Paraquat results in increased activity of CAT protein]; Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of CAT protein]
Paraquat results in decreased expression of CAT mRNA; Paraquat results in decreased expression of CAT protein
CAT protein results in decreased susceptibility to Paraquat
Curcumin inhibits the reaction [Paraquat results in decreased activity of CAT protein]; Hydroxylamine inhibits the reaction [CAT protein results in decreased susceptibility to Paraquat]; NFKB1 protein mutant form inhibits the reaction [Paraquat results in increased expression of CAT mRNA]; NFKBIA protein mutant form inhibits the reaction [Paraquat results in increased expression of CAT mRNA]; pirfenidone inhibits the reaction [Paraquat results in increased activity of CAT protein]; Resveratrol inhibits the reaction [Paraquat results in decreased activity of CAT protein]; SIRT1 protein affects the reaction [Paraquat affects the activity of CAT protein]; TO-901317 inhibits the reaction [Paraquat results in decreased activity of CAT protein]
[Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in decreased activity of CAT protein]; [NR1I2 protein results in decreased activity of CAT protein] which results in increased susceptibility to Paraquat; [Paraquat co-treated with Thioctic Acid] results in increased expression of CAT mRNA; [Plant Extracts co-treated with Paraquat] results in increased expression of CAT mRNA; [SOD1 protein co-treated with CAT protein] results in decreased susceptibility to Paraquat; CAT protein inhibits the reaction [[POR protein results in increased metabolism of Paraquat] which results in increased abundance of Hydrogen Peroxide]; CAT protein inhibits the reaction [Paraquat results in decreased expression of GCLC protein]; CAT protein inhibits the reaction [Paraquat results in decreased expression of NFE2L2 mRNA]; CAT protein inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [Paraquat results in increased activity of CASP7 protein]; CAT protein inhibits the reaction [Paraquat results in increased activity of ODC1 protein]; CAT protein inhibits the reaction [Paraquat results in increased expression of JUN mRNA]; CAT protein inhibits the reaction [Paraquat results in increased expression of MIR153 mRNA]; Dimethyl Sulfoxide inhibits the reaction [Paraquat results in increased expression of CAT mRNA]; IL1A protein promotes the reaction [Paraquat results in increased expression of CAT protein]; IL1B protein promotes the reaction [Paraquat results in increased expression of CAT protein]; Plant Extracts promotes the reaction [Paraquat results in increased expression of CAT mRNA]; TNF protein promotes the reaction [Paraquat results in increased expression of CAT protein]
CAT protein modified form results in increased susceptibility to Paraquat; CAT protein results in increased susceptibility to Paraquat
CTD PMID:7662713, PMID:8317554, PMID:9169468, PMID:10699569, PMID:10751631, PMID:10754530, PMID:10959798, PMID:11178967, PMID:11325355, PMID:11728812, PMID:12180188, PMID:12826488, PMID:14759608, PMID:15177642, PMID:15190189, PMID:15754033, PMID:16195250, PMID:16677106, PMID:17107770, PMID:17215068, PMID:17935786, PMID:18620719, PMID:19486935, PMID:20095329, PMID:20553223, PMID:20883675, PMID:21215309, PMID:22736252, PMID:23649336, PMID:24141985, PMID:24376630, PMID:24799198, PMID:24812154, PMID:24866057, PMID:25169090, PMID:25461551, PMID:26468117, PMID:26598004, PMID:26649146, PMID:26708779, PMID:26935021, PMID:27993944, PMID:28480221, PMID:28921394, PMID:29273418, PMID:29859004, PMID:30243747, PMID:32020686 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 increases expression EXP Paraquat results in increased expression of CAV1 mRNA; Paraquat results in increased expression of CAV1 protein CTD PMID:26813466 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cbl Cbl proto-oncogene multiple interactions
increases phosphorylation
EXP CBL protein affects the reaction [Paraquat results in decreased expression of PDGFRA protein]
Paraquat results in increased phosphorylation of CBL protein
CTD PMID:17298174 NCBI chr 8:48,481,256...48,564,775
Ensembl chr 8:48,489,036...48,564,722
JBrowse link
G Ccdc88a coiled coil domain containing 88A multiple interactions
increases expression
ISO [Paraquat co-treated with Maneb] affects the expression of CCDC88A mRNA
Paraquat results in increased expression of CCDC88A mRNA
CTD PMID:22563483 NCBI chr14:113,771,093...113,936,376
Ensembl chr14:113,867,209...113,932,263
JBrowse link
G Cckbr cholecystokinin B receptor decreases expression EXP Paraquat results in decreased expression of CCKBR mRNA CTD PMID:17077588 NCBI chr 1:170,262,218...170,272,298
Ensembl chr 1:170,262,156...170,272,298
JBrowse link
G Ccl19 C-C motif chemokine ligand 19 multiple interactions
increases expression
ISO [Paraquat co-treated with Maneb] affects the expression of CCL19 mRNA
Paraquat results in increased expression of CCL19 mRNA
CTD PMID:22563483 NCBI chr 5:58,181,025...58,182,969
Ensembl chr 5:58,181,026...58,183,017
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
affects expression
increases expression
EXP
ISO
[Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased secretion of CCL2 protein; Ambroxol affects the reaction [Paraquat results in increased expression of CCL2 mRNA]; SB 203580 inhibits the reaction [[Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased secretion of CCL2 protein]
Paraquat affects the expression of CCL2 mRNA
CTD PMID:16324872, PMID:21921364, PMID:24376630, PMID:26345256 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression
multiple interactions
ISO Paraquat results in increased expression of CCL20 protein
PTPN6 protein inhibits the reaction [Paraquat results in increased expression of CCL20 protein]
CTD PMID:18441283 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001
JBrowse link
G Ccl21 C-C motif chemokine ligand 21 multiple interactions
increases expression
ISO [Paraquat co-treated with Maneb] affects the expression of CCL21 mRNA; [Paraquat co-treated with Maneb] affects the expression of CCL21A mRNA
Paraquat results in increased expression of CCL21 mRNA; Paraquat results in increased expression of CCL21A mRNA
CTD PMID:22563483 NCBI chr 5:58,197,678...58,198,782
Ensembl chr 5:58,197,680...58,198,782
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CCL3 mRNA]; Dapsone inhibits the reaction [Paraquat results in increased expression of CCL3 mRNA] CTD PMID:16324872, PMID:21765237 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccn1 cellular communication network factor 1 increases expression ISO Paraquat results in increased expression of CCN1 mRNA CTD PMID:12595580 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions
increases expression
ISO
EXP
[CCN2 protein co-treated with Paraquat] affects the expression of MMP2 mRNA; [CCN2 protein co-treated with Paraquat] affects the expression of MMP9 mRNA; [CCN2 protein co-treated with Paraquat] affects the expression of TIMP1 mRNA; [Paraquat co-treated with TGFB1 protein] results in increased expression of CCN2 mRNA; Saralasin inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA]; Saralasin inhibits the reaction [Paraquat results in increased expression of CCN2 protein]; TGFB1 protein promotes the reaction [Paraquat results in increased expression of CCN2 protein]; Triamcinolone Acetonide promotes the reaction [Paraquat results in increased expression of CCN2 mRNA]
ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA]; plant extract, Puerariae Radix inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA]; plant extract, Puerariae Radix inhibits the reaction [Paraquat results in increased expression of CCN2 protein]
Paraquat results in increased expression of CCN2 mRNA; Paraquat results in increased expression of CCN2 protein
prolinedithiocarbamate inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA]; prolinedithiocarbamate inhibits the reaction [Paraquat results in increased expression of CCN2 protein]
CTD PMID:12595580, PMID:15728566, PMID:16767377, PMID:20035857, PMID:23433149, PMID:25815693, PMID:25945502, PMID:26129822, PMID:26758514, PMID:27682480 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccna2 cyclin A2 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CCNA2 mRNA CTD PMID:28012437 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CCNB1 mRNA CTD PMID:28012437 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnb2 cyclin B2 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CCNB2 mRNA CTD PMID:28012437 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Ccnc cyclin C increases expression ISO Paraquat results in increased expression of CCNC mRNA CTD PMID:20883675 NCBI chr 5:35,865,598...35,883,732
Ensembl chr 5:35,865,605...35,883,706
JBrowse link
G Ccnd1 cyclin D1 affects expression
multiple interactions
decreases expression
EXP
ISO
Paraquat affects the expression of CCND1 mRNA
[Maneb co-treated with Paraquat] results in decreased expression of CCND1 mRNA
LGK974 inhibits the reaction [Paraquat results in decreased expression of CCND1 protein]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of CCND1 mRNA]
CTD PMID:16854511, PMID:26887261, PMID:29859004, PMID:30171970, PMID:30205152 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccnd2 cyclin D2 decreases expression
multiple interactions
EXP
ISO
Paraquat results in decreased expression of CCND2 mRNA
[Maneb co-treated with Paraquat] results in decreased expression of CCND2 mRNA
CTD PMID:17935786, PMID:28619522, PMID:29859004 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207
JBrowse link
G Ccnd3 cyclin D3 decreases expression EXP Paraquat results in decreased expression of CCND3 mRNA CTD PMID:17935786 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943
JBrowse link
G Ccne1 cyclin E1 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CCNE1 mRNA CTD PMID:28012437 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Ccne2 cyclin E2 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CCNE2 mRNA CTD PMID:28012437 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Ccng1 cyclin G1 increases expression EXP Paraquat results in increased expression of CCNG1 mRNA CTD PMID:17935786 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Ccs copper chaperone for superoxide dismutase increases response to substance ISO CCS gene mutant form results in increased susceptibility to Paraquat CTD PMID:10694572 NCBI chr 1:220,075,251...220,096,319
Ensembl chr 1:220,075,247...220,096,404
JBrowse link
G Cd14 CD14 molecule increases expression ISO Paraquat results in increased expression of CD14 mRNA CTD PMID:28012437 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153
JBrowse link
G Cd27 CD27 molecule decreases expression ISO Paraquat results in decreased expression of CD27 mRNA CTD PMID:18836921 NCBI chr 4:157,744,881...157,751,609
Ensembl chr 4:157,744,882...157,750,088
JBrowse link
G Cd38 CD38 molecule decreases expression EXP Paraquat results in decreased expression of CD38 mRNA CTD PMID:18198484 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672
JBrowse link
G Cd40 CD40 molecule increases expression ISO Paraquat results in increased expression of CD40 mRNA CTD PMID:18836921 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704
JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression EXP Paraquat results in decreased expression of CD44 mRNA CTD PMID:18198484 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658
JBrowse link
G Cd47 Cd47 molecule increases expression ISO Paraquat results in increased expression of CD47 protein CTD PMID:29287252 NCBI chr11:53,511,485...53,575,754
Ensembl chr11:53,514,595...53,575,175
JBrowse link
G Cd68 Cd68 molecule decreases expression
multiple interactions
ISO Paraquat results in decreased expression of CD68 mRNA
[MTHFR gene polymorphism affects the susceptibility to Paraquat] which results in increased expression of CD68 protein; [Paraquat co-treated with Maneb] results in increased expression of CD68 mRNA; Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CD68 mRNA]
CTD PMID:21371552, PMID:30726997, PMID:32169474 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
JBrowse link
G Cd70 Cd70 molecule decreases expression ISO Paraquat results in decreased expression of CD70 mRNA CTD PMID:18836921 NCBI chr 9:9,842,585...9,845,728
Ensembl chr 9:9,842,585...9,845,728
JBrowse link
G Cd80 Cd80 molecule increases expression EXP Paraquat results in increased expression of CD80 mRNA CTD PMID:18198484 NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353
JBrowse link
G Cd86 CD86 molecule increases expression
decreases expression
EXP
ISO
Paraquat results in increased expression of CD86 mRNA
Paraquat results in increased expression of CD86 protein
Paraquat results in decreased expression of CD86 mRNA
CTD PMID:24521700, PMID:28467894, PMID:31299241 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cd8b CD8b molecule decreases expression ISO Paraquat results in decreased expression of CD8B mRNA CTD PMID:21371552 NCBI chr 4:99,185,960...99,201,887
Ensembl chr 4:99,185,885...99,202,023
JBrowse link
G Cdc20 cell division cycle 20 decreases expression
multiple interactions
increases expression
EXP
ISO
Paraquat results in decreased expression of CDC20 mRNA
[ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDC20 mRNA
Paraquat results in increased expression of CDC20 mRNA
CTD PMID:18198484, PMID:26345256, PMID:28012437 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdc25a cell division cycle 25A affects expression EXP Paraquat affects the expression of CDC25A mRNA CTD PMID:16854511 NCBI chr 8:117,953,223...117,971,552
Ensembl chr 8:117,953,444...117,971,519
JBrowse link
G Cdc25b cell division cycle 25B decreases expression ISO Paraquat results in decreased expression of CDC25B mRNA CTD PMID:28012437 NCBI chr 3:123,731,539...123,741,696
Ensembl chr 3:123,731,539...123,741,339
JBrowse link
G Cdc25c cell division cycle 25C multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDC25C mRNA CTD PMID:28012437 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224
JBrowse link
G Cdc40 cell division cycle 40 increases expression ISO Paraquat results in increased expression of CDC40 mRNA CTD PMID:21371552 NCBI chr20:48,503,973...48,574,546
Ensembl chr20:48,503,973...48,574,546
JBrowse link
G Cdh1 cadherin 1 decreases expression
multiple interactions
EXP Paraquat results in decreased expression of CDH1 mRNA; Paraquat results in decreased expression of CDH1 protein
Anthocyanins inhibits the reaction [Paraquat results in decreased expression of CDH1 protein]; NFE2L2 protein promotes the reaction [Sirolimus inhibits the reaction [Paraquat results in decreased expression of CDH1 protein]]; Sirolimus inhibits the reaction [Paraquat results in decreased expression of CDH1 mRNA]; Sirolimus inhibits the reaction [Paraquat results in decreased expression of CDH1 protein]; sulforafan inhibits the reaction [Paraquat results in decreased expression of CDH1 protein]
CTD PMID:25873302, PMID:28624451, PMID:30403199 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdhr4 cadherin-related family member 4 decreases expression
multiple interactions
ISO Paraquat results in decreased expression of CDHR4 mRNA
[Paraquat co-treated with Maneb] affects the expression of CDHR4 mRNA
CTD PMID:22563483 NCBI chr 8:116,771,377...116,779,242 JBrowse link
G Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CDIPT mRNA CTD PMID:18386188 NCBI chr 1:198,409,186...198,413,497
Ensembl chr 1:198,409,360...198,413,497
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions
decreases expression
ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDK1 mRNA; Paraquat affects the reaction [ATG7 protein affects the expression of CDK1 mRNA]; Paraquat affects the reaction [ATG7 protein affects the expression of CDK1 protein]
Paraquat results in decreased expression of CDK1 mRNA; Paraquat results in decreased expression of CDK1 protein
CTD PMID:28012437 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDK2 mRNA; [Maneb co-treated with Paraquat] results in decreased expression of CDK2 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of CDK2 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of CDK2 mRNA] CTD PMID:23963992, PMID:28012437 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of CDK5R1 mRNA CTD PMID:23017109 NCBI chr10:67,862,054...67,863,255
Ensembl chr10:67,862,054...67,863,255
JBrowse link
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of CDK5RAP1 mRNA CTD PMID:23017109 NCBI chr 3:149,835,953...149,870,429
Ensembl chr 3:149,703,848...149,870,413
JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of CDK5RAP2 mRNA; LRRK2 protein mutant form inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CDK5RAP2 mRNA]; SNCA protein inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CDK5RAP2 mRNA] CTD PMID:23017109 NCBI chr 5:86,387,238...86,554,108
Ensembl chr 5:86,387,078...86,554,102
JBrowse link
G Cdk8 cyclin-dependent kinase 8 decreases expression ISO Paraquat results in decreased expression of CDK8 mRNA CTD PMID:21371552 NCBI chr12:10,496,273...10,561,335 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
decreases expression
ISO Paraquat results in increased expression of CDKN1A mRNA; Paraquat results in increased expression of CDKN1A protein
[ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDKN1A mRNA; [Maneb co-treated with Paraquat] results in increased expression of CDKN1A mRNA; ATG7 protein affects the reaction [Paraquat results in increased expression of CDKN1A protein]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CDKN1A mRNA]
Paraquat results in decreased expression of CDKN1A mRNA
CTD PMID:12595580, PMID:20883675, PMID:21371552, PMID:23963992, PMID:24060684, PMID:28012437, PMID:31368498 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression ISO Paraquat results in decreased expression of CDKN1C mRNA CTD PMID:21371552 NCBI chr 1:216,661,067...216,663,791
Ensembl chr 1:216,661,080...216,663,721
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression
multiple interactions
EXP Paraquat results in increased expression of CDKN2A mRNA
[Maneb co-treated with Paraquat] results in increased expression of CDKN2A mRNA
CTD PMID:29859004 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C increases expression ISO Paraquat results in increased expression of CDKN2C mRNA CTD PMID:28012437 NCBI chr 5:129,347,731...129,352,886
Ensembl chr 5:129,347,732...129,352,886
JBrowse link
G Cdo1 cysteine dioxygenase type 1 affects expression EXP Paraquat affects the expression of CDO1 mRNA CTD PMID:16854511 NCBI chr18:40,702,027...40,716,901
Ensembl chr18:40,701,984...40,716,686
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO Paraquat results in increased expression of CEBPB mRNA CTD PMID:12595580, PMID:23613995 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta decreases expression
multiple interactions
ISO Paraquat results in decreased expression of CEBPD mRNA
[Paraquat co-treated with Maneb] affects the expression of CEBPD mRNA
CTD PMID:22563483 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146
JBrowse link
G Cep290 centrosomal protein 290 multiple interactions
increases expression
ISO [Paraquat co-treated with Maneb] affects the expression of CEP290 mRNA
Paraquat results in increased expression of CEP290 mRNA
CTD PMID:22563483 NCBI chr 7:40,217,269...40,306,327
Ensembl chr 7:40,217,269...40,306,327
JBrowse link
G Cfl1 cofilin 1 increases expression EXP Paraquat results in increased expression of CFL1 mRNA CTD PMID:17077588 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Cftr CF transmembrane conductance regulator affects expression
affects splicing
EXP
ISO
Paraquat affects the expression of CFTR mRNA
Paraquat affects the splicing of CFTR exon
CTD PMID:15206577, PMID:27111068 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Chat choline O-acetyltransferase decreases activity
decreases expression
EXP Paraquat results in decreased activity of CHAT protein
Paraquat results in decreased expression of CHAT mRNA
CTD PMID:24521700, PMID:28916328 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CHEK1 mRNA CTD PMID:28012437 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of CHRM2 mRNA CTD PMID:23017109 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit affects expression EXP Paraquat affects the expression of CHRNA5 mRNA CTD PMID:18198484 NCBI chr 8:59,561,817...59,590,172
Ensembl chr 8:59,561,721...59,590,172
JBrowse link
G Chrna6 cholinergic receptor nicotinic alpha 6 subunit multiple interactions
affects expression
ISO
EXP
Nicotine inhibits the reaction [Paraquat results in decreased expression of [CHRNA6 protein binds to CHRNB2 protein]]; Paraquat results in decreased expression of [CHRNA6 protein binds to CHRNB2 protein]
Paraquat affects the expression of CHRNA6 mRNA
CTD PMID:17227438, PMID:18198484 NCBI chr16:68,860,018...68,866,718
Ensembl chr16:68,860,018...68,866,718
JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit increases expression EXP Paraquat results in increased expression of CHRNA7 mRNA CTD PMID:18198484 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196
JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit increases expression EXP Paraquat results in increased expression of CHRNB1 mRNA CTD PMID:17077588 NCBI chr10:56,390,671...56,403,255
Ensembl chr10:56,390,671...56,403,188
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO Nicotine inhibits the reaction [Paraquat results in decreased expression of [CHRNA6 protein binds to CHRNB2 protein]]; Paraquat results in decreased expression of [CHRNA6 protein binds to CHRNB2 protein] CTD PMID:17227438 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit increases expression EXP Paraquat results in increased expression of CHRNE mRNA CTD PMID:17077588 NCBI chr10:57,238,960...57,246,750
Ensembl chr10:57,238,946...57,243,435
JBrowse link
G Chrng cholinergic receptor nicotinic gamma subunit affects expression EXP Paraquat affects the expression of CHRNG mRNA CTD PMID:18198484 NCBI chr 9:94,302,218...94,308,591 JBrowse link
G Cidea cell death-inducing DFFA-like effector a increases expression ISO Paraquat results in increased expression of CIDEA mRNA CTD PMID:18836921 NCBI chr18:63,082,861...63,108,450
Ensembl chr18:63,098,144...63,108,051
JBrowse link
G Cideb cell death-inducing DFFA-like effector b increases expression ISO Paraquat results in increased expression of CIDEB mRNA CTD PMID:18836921 NCBI chr15:34,439,844...34,444,244
Ensembl chr15:34,439,876...34,444,244
JBrowse link
G Cirbp cold inducible RNA binding protein multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CIRBP mRNA CTD PMID:18386188 NCBI chr 7:12,400,066...12,405,054
Ensembl chr 7:12,401,207...12,405,022
JBrowse link
G Clca1 chloride channel accessory 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of CLCA1 mRNA; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of CLCA1 mRNA] CTD PMID:23963992 NCBI chr 2:250,897,980...250,923,711
Ensembl chr 2:250,897,969...250,923,744
JBrowse link
G Cldn1 claudin 1 decreases expression ISO Paraquat results in decreased expression of CLDN1 protein CTD PMID:30698896 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416
JBrowse link
G Clk3 CDC-like kinase 3 increases expression EXP Paraquat results in increased expression of CLK3 mRNA CTD PMID:16328009 NCBI chr 8:62,528,135...62,543,550
Ensembl chr 8:62,528,225...62,542,622
JBrowse link
G Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit X increases expression ISO Paraquat results in increased expression of CLPX mRNA CTD PMID:21371552 NCBI chr 8:70,789,137...70,843,133
Ensembl chr 8:70,789,256...70,843,123
JBrowse link
G Clspn claspin decreases expression ISO Paraquat results in decreased expression of CLSPN mRNA CTD PMID:23613995 NCBI chr 5:144,577,670...144,617,507
Ensembl chr 5:144,581,427...144,616,335
JBrowse link
G Clu clusterin multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CLU mRNA CTD PMID:18386188 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cma1 chymase 1 multiple interactions
increases expression
ISO
EXP
CMA1 protein promotes the reaction [Paraquat results in increased expression of ACTA2 protein]; CMA1 protein promotes the reaction [Paraquat results in increased expression of AGT protein modified form]; CMA1 protein promotes the reaction [Paraquat results in increased expression of TGFB1 protein]
Paraquat results in increased expression of CMA1 mRNA
Paraquat results in increased expression of CMA1 mRNA; Paraquat results in increased expression of CMA1 protein
CTD PMID:18198484, PMID:19969051 NCBI chr15:34,601,037...34,603,819
Ensembl chr15:34,601,037...34,603,819
JBrowse link
G Cmklr1 chemerin chemokine-like receptor 1 increases expression EXP Paraquat results in increased expression of CMKLR1 mRNA CTD PMID:17077588 NCBI chr12:48,743,556...48,796,582
Ensembl chr12:48,789,261...48,793,553
JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 increases expression ISO Paraquat results in increased expression of CMPK2 mRNA CTD PMID:21371552 NCBI chr 6:45,683,242...45,694,824
Ensembl chr 6:45,683,234...45,694,822
JBrowse link
G Cnr2 cannabinoid receptor 2 decreases expression
multiple interactions
EXP Paraquat results in decreased expression of CNR2 protein
1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Paraquat results in decreased expression of CNR2 protein]
CTD PMID:24963491 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression
EXP
ISO
[Paraquat co-treated with Oxygen] results in increased expression of COL1A1 mRNA; Ambroxol affects the reaction [Paraquat results in increased expression of COL1A1 mRNA]; Anthocyanins inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]; Thalidomide inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]; Thalidomide inhibits the reaction [Paraquat results in increased expression of COL1A1 protein]
Paraquat results in increased expression of COL1A1 mRNA; Paraquat results in increased expression of COL1A1 protein
enterotoxin C, staphylococcal analog inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]; Fingolimod Hydrochloride inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]; pirfenidone inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]; thymoquinone inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]
Saralasin inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]
CTD PMID:12882763, PMID:17215068, PMID:19969051, PMID:20035857, PMID:21921364, PMID:24893116, PMID:25304964, PMID:25873302, PMID:26099602, PMID:26221080, PMID:26345256, PMID:27375216, PMID:29273418, PMID:30403199 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col2a1 collagen type II alpha 1 chain decreases expression ISO Paraquat results in decreased expression of COL2A1 mRNA CTD PMID:26108578 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997
JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions
increases expression
ISO
EXP
ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]; ADIPOR1 protein promotes the reaction [ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]]; Saralasin inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]
enterotoxin C, staphylococcal analog inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]; Fingolimod Hydrochloride inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]; plant extract, Puerariae Radix inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]
Paraquat results in increased expression of COL3A1 mRNA; Paraquat results in increased expression of COL3A1 protein
Ambroxol affects the reaction [Paraquat results in increased expression of COL3A1 mRNA]; Losartan inhibits the reaction [Paraquat results in increased expression of COL3A1 protein]
CTD PMID:20035857, PMID:21921364, PMID:24893116, PMID:25233898, PMID:25304964, PMID:25873302, PMID:25945502, PMID:26099602, PMID:26758514 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Col4a1 collagen type IV alpha 1 chain multiple interactions
increases expression
ISO pirfenidone inhibits the reaction [Paraquat results in increased expression of COL4A1 mRNA]; thymoquinone inhibits the reaction [Paraquat results in increased expression of COL4A1 mRNA] CTD PMID:27375216, PMID:29273418 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153
JBrowse link
G Col6a1 collagen type VI alpha 1 chain increases expression ISO Paraquat results in increased expression of COL6A1 mRNA CTD PMID:26345256 NCBI chr20:12,657,913...12,676,370
Ensembl chr20:12,658,065...12,675,561
JBrowse link
G Comt catechol-O-methyltransferase increases expression EXP Paraquat results in increased expression of COMT mRNA CTD PMID:17935786 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622
JBrowse link
G Cope COPI coat complex subunit epsilon multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of COPE mRNA CTD PMID:18386188 NCBI chr16:20,863,141...20,873,516
Ensembl chr16:20,863,141...20,873,521
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 affects expression
increases expression
decreases expression
EXP Paraquat affects the expression of COX4I1 mRNA
Paraquat results in increased expression of COX4I1 protein
Paraquat results in decreased expression of COX4I1 mRNA
CTD PMID:15206577, PMID:18198484, PMID:24521700 NCBI chr19:54,245,958...54,252,198
Ensembl chr19:54,245,950...54,252,225
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A increases expression
multiple interactions
EXP
ISO
Paraquat results in increased expression of COX5A protein
[Maneb co-treated with Paraquat] results in decreased expression of COX5A protein; Levodopa inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of COX5A protein]; Minocycline inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of COX5A protein]; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of COX5A protein]
CTD PMID:23562983, PMID:24521700 NCBI chr 8:62,298,358...62,309,765
Ensembl chr 8:62,298,358...62,309,765
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B decreases expression
increases expression
EXP Paraquat results in decreased expression of COX5B mRNA
Paraquat results in increased expression of COX5B protein
CTD PMID:17077588, PMID:24521700 NCBI chr 9:43,259,706...43,262,039
Ensembl chr 9:43,259,709...43,262,040
JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of COX6A1 mRNA CTD PMID:18386188 NCBI chr12:47,024,442...47,027,495
Ensembl chr12:47,024,442...47,027,495
JBrowse link
G Cox6b1 cytochrome c oxidase subunit 6B1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of COX6B1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of COX6B1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of COX6B1 mRNA] CTD PMID:23963992 NCBI chr 1:89,075,987...89,084,834
Ensembl chr 1:89,075,975...89,084,859
Ensembl chr 2:89,075,975...89,084,859
JBrowse link
G Cox6c cytochrome c oxidase subunit 6C increases expression EXP Paraquat results in increased expression of COX6C protein CTD PMID:24521700 NCBI chr 7:74,723,177...74,735,650
Ensembl chr 7:74,723,179...74,735,650
JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 decreases expression
multiple interactions
EXP
ISO
Paraquat results in decreased expression of COX7A2 mRNA
[Paraquat co-treated with Maneb] results in decreased expression of COX7A2 mRNA
CTD PMID:17077588, PMID:18386188 NCBI chr 8:87,209,529...87,213,627
Ensembl chr 8:87,209,530...87,213,627
JBrowse link
G Cox7a2l cytochrome c oxidase subunit 7A2 like multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of COX7A2L mRNA CTD PMID:18386188 NCBI chr 6:6,695,807...6,709,790
Ensembl chr 6:6,695,827...6,709,783
JBrowse link
G Cplx1 complexin 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CPLX1 mRNA; [Paraquat co-treated with Maneb] results in decreased expression of CPLX1 protein CTD PMID:17532186 NCBI chr14:2,194,895...2,226,610
Ensembl chr14:2,194,933...2,226,598
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP Paraquat results in increased expression of CPT1A mRNA CTD PMID:18198484 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain increases expression ISO Paraquat results in increased expression of CRADD mRNA CTD PMID:18836921 NCBI chr 7:36,395,665...36,408,588
Ensembl chr 7:36,395,665...36,408,588
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation
multiple interactions
ISO
EXP
Paraquat results in increased phosphorylation of CREB1 protein
[Paraquat co-treated with Maneb] results in decreased expression of CREB1 mRNA; [Paraquat co-treated with Maneb] results in decreased expression of CREB1 protein; [Paraquat co-treated with Maneb] results in decreased expression of CREB1 protein modified form
[Maneb co-treated with Paraquat] results in decreased expression of CREB1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of CREB1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of CREB1 mRNA]
CTD PMID:16797015, PMID:23963992, PMID:27460631 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Creb3 cAMP responsive element binding protein 3 increases expression ISO Paraquat results in increased expression of CREB3 mRNA CTD PMID:21371552 NCBI chr 5:59,063,532...59,068,196
Ensembl chr 5:59,063,531...59,068,188
JBrowse link
G Crebbp CREB binding protein increases expression
decreases expression
EXP
ISO
Paraquat results in increased expression of CREBBP protein
Paraquat results in decreased expression of CREBBP mRNA
CTD PMID:20478973, PMID:28619522 NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039
JBrowse link
G Crip2 cysteine-rich protein 2 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CRIP2 mRNA CTD PMID:18386188 NCBI chr 6:137,953,545...137,958,491
Ensembl chr 6:137,953,545...137,958,490
JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 affects expression EXP Paraquat affects the expression of CRISPLD2 mRNA CTD PMID:16854511 NCBI chr19:52,647,038...52,705,118
Ensembl chr19:52,647,070...52,705,131
JBrowse link
G Crlf2 cytokine receptor-like factor 2 decreases expression
multiple interactions
ISO Paraquat results in decreased expression of CRLF2 mRNA
[Paraquat co-treated with Maneb] affects the expression of CRLF2 mRNA
CTD PMID:22563483 NCBI chr14:1,456,843...1,461,543
Ensembl chr14:1,456,844...1,461,543
JBrowse link
G Crot carnitine O-octanoyltransferase multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CROT mRNA CTD PMID:18386188 NCBI chr 4:22,079,837...22,116,265
Ensembl chr 4:22,081,604...22,116,265
JBrowse link
G Crtc2 CREB regulated transcription coactivator 2 decreases expression
multiple interactions
ISO Paraquat results in decreased expression of CRTC2 mRNA
WNT1 protein inhibits the reaction [Paraquat results in decreased expression of CRTC2 mRNA]
CTD PMID:30171970 NCBI chr 2:189,615,928...189,625,646
Ensembl chr 2:189,615,948...189,626,051
JBrowse link
G Csf1r colony stimulating factor 1 receptor affects expression
multiple interactions
increases expression
EXP
ISO
Paraquat affects the expression of CSF1R mRNA
[Paraquat co-treated with Maneb] results in increased expression of CSF1R mRNA; Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CSF1R mRNA]
Paraquat results in increased expression of CSF1R mRNA
CTD PMID:15206577, PMID:17077588, PMID:18198484, PMID:21371552, PMID:32169474 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Csf2 colony stimulating factor 2 increases expression ISO Paraquat results in increased expression of CSF2 mRNA CTD PMID:22938100 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csf2ra colony stimulating factor 2 receptor subunit alpha multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of CSF2RA mRNA; Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CSF2RA mRNA] CTD PMID:32169474 NCBI chr14:1,462,292...1,467,264
Ensembl chr14:1,462,358...1,467,264
JBrowse link
G Csf3 colony stimulating factor 3 increases expression ISO Paraquat results in increased expression of CSF3 protein CTD PMID:26988026 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Csnk1g2 casein kinase 1, gamma 2 decreases expression ISO Paraquat results in decreased expression of CSNK1G2 mRNA CTD PMID:21371552 NCBI chr 7:11,944,957...11,963,268
Ensembl chr 7:11,944,958...11,963,268
JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 increases expression ISO Paraquat results in increased expression of CSNK2A2 protein CTD PMID:26649146 NCBI chr19:9,972,537...10,012,043
Ensembl chr19:9,972,537...10,012,043
JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 affects expression EXP Paraquat affects the expression of CSPG4 mRNA CTD PMID:16854511 NCBI chr 8:61,532,465...61,567,510
Ensembl chr 8:61,532,465...61,567,510
JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
affects localization
decreases expression
decreases response to substance
ISO
EXP
CTNNB1 protein inhibits the reaction [Paraquat results in increased abundance of Reactive Oxygen Species]; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of CTNNB1 protein]; Paraquat inhibits the reaction [CTNNB1 protein binds to MPZ promoter]; Paraquat inhibits the reaction [CTNNB1 protein binds to PMP22 promoter]
LGK974 inhibits the reaction [Paraquat affects the localization of CTNNB1 protein]; LGK974 inhibits the reaction [Paraquat results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; Paraquat results in increased expression of and results in decreased phosphorylation of CTNNB1 protein; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of CTNNB1 mRNA]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of CTNNB1 protein]
Paraquat results in decreased expression of CTNNB1 mRNA; Paraquat results in decreased expression of CTNNB1 protein
CTNNB1 protein results in decreased susceptibility to Paraquat
CTD PMID:23620592, PMID:26887261, PMID:27788593, PMID:30171970, PMID:30205152 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372
JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 increases expression ISO Paraquat results in increased expression of CTNNBIP1 mRNA CTD PMID:28619522 NCBI chr 5:166,464,170...166,513,030
Ensembl chr 5:166,464,252...166,513,027
JBrowse link
G Ctnnd1 catenin delta 1 multiple interactions
decreases expression
ISO mangiferin inhibits the reaction [Paraquat results in decreased expression of and affects the localization of CTNND1 protein]; mangiferin inhibits the reaction [Paraquat results in decreased expression of CTNND1 mRNA alternative form]; Paraquat results in decreased expression of and affects the localization of CTNND1 protein CTD PMID:24912632 NCBI chr 3:72,001,904...72,053,047
Ensembl chr 3:72,002,152...72,053,049
JBrowse link
G Ctnnd2 catenin delta 2 decreases expression ISO Paraquat results in decreased expression of CTNND2 mRNA CTD PMID:21371552 NCBI chr 2:83,227,247...84,094,315
Ensembl chr 2:83,393,282...84,094,315
JBrowse link
G Ctrb1 chymotrypsinogen B1 increases expression EXP Paraquat results in increased expression of CTRB mRNA CTD PMID:18198484 NCBI chr19:43,906,344...43,911,020
Ensembl chr19:43,906,292...43,911,057
JBrowse link
G Ctsb cathepsin B decreases expression
multiple interactions
decreases activity
ISO Paraquat results in decreased expression of CTSB mRNA
APOD protein inhibits the reaction [Paraquat results in decreased activity of CTSB protein]
CTD PMID:16797015, PMID:28182653 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsc cathepsin C decreases expression ISO Paraquat results in decreased expression of CTSC mRNA CTD PMID:16797015 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983
JBrowse link
G Ctsd cathepsin D decreases expression ISO Paraquat results in decreased expression of CTSD mRNA CTD PMID:16797015 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Ctsh cathepsin H decreases expression ISO Paraquat results in decreased expression of CTSH mRNA CTD PMID:16797015 NCBI chr 8:97,439,155...97,458,293
Ensembl chr 8:97,439,161...97,458,287
JBrowse link
G Ctsk cathepsin K increases expression ISO Paraquat results in increased expression of CTSK mRNA CTD PMID:26345256 NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446
JBrowse link
G Ctsl cathepsin L multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of CTSL mRNA; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CTSL mRNA] CTD PMID:23963992 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cul1 cullin 1 increases expression ISO Paraquat results in increased expression of CUL1 mRNA CTD PMID:21371552, PMID:28619522 NCBI chr 4:77,211,814...77,283,369
Ensembl chr 4:77,211,692...77,280,250
JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 decreases response to substance ISO CX3CR1 protein results in decreased susceptibility to Paraquat CTD PMID:23299473 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO Paraquat results in increased expression of CXCL10 mRNA CTD PMID:22230393, PMID:26345256 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 increases expression ISO Paraquat results in increased expression of CXCL11 mRNA CTD PMID:22230393 NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
multiple interactions
EXP
ISO
Paraquat results in increased expression of CXCL2 protein
Paraquat results in increased expression of CXCL2 mRNA; Paraquat results in increased expression of CXCL2 protein
1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Paraquat results in increased expression of CXCL2 protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CXCL2 protein]; Paraquat promotes the reaction [endotoxin, Escherichia coli results in increased expression of CXCL2 protein]; SB 203580 inhibits the reaction [Paraquat promotes the reaction [endotoxin, Escherichia coli results in increased expression of CXCL2 protein]]; SB 203580 inhibits the reaction [Paraquat results in increased expression of CXCL2 protein]
[Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased secretion of CXCL2 protein; SB 203580 inhibits the reaction [[Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased secretion of CXCL2 protein]
CTD PMID:12504350, PMID:16324872, PMID:16919916, PMID:24376630 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression
increases expression
EXP
ISO
Paraquat results in decreased expression of CXCL3 mRNA
Paraquat results in increased expression of CXCL1 protein
CTD PMID:18198484, PMID:26988026 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression EXP Paraquat results in decreased expression of CXCR4 mRNA CTD PMID:18198484 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878
JBrowse link
G Cyb5a cytochrome b5 type A increases expression ISO Paraquat results in increased expression of CYB5A mRNA CTD PMID:21371552 NCBI chr18:81,694,818...81,726,821
Ensembl chr18:81,694,808...81,726,821
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of NOX2 mRNA; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOX2 mRNA]; diphenyleneiodonium inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOX2 mRNA] CTD PMID:30797899 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cyc1 cytochrome c-1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CYC1 mRNA CTD PMID:18386188 NCBI chr 7:117,409,576...117,411,953
Ensembl chr 7:117,409,576...117,411,953
JBrowse link
G Cycs cytochrome c, somatic multiple interactions
increases expression
affects localization
ISO [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of CYCS mRNA]; salubrinal inhibits the reaction [Paraquat affects the localization of CYCS protein]
Paraquat results in increased expression of CYCS mRNA; Paraquat results in increased expression of CYCS protein
CTD PMID:20929985, PMID:22736252, PMID:26649146 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cygb cytoglobin increases expression EXP Paraquat results in increased expression of CYGB mRNA CTD PMID:20388547 NCBI chr10:105,618,325...105,628,091
Ensembl chr10:105,618,326...105,628,091
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression EXP Paraquat results in increased expression of CYP11A1 mRNA CTD PMID:18198484 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity EXP Paraquat results in decreased activity of CYP1A1 protein CTD PMID:17481832 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity
increases expression
multiple interactions
EXP Paraquat results in increased activity of CYP1A2 protein
Paraquat results in increased expression of CYP1A2 mRNA; Paraquat results in increased expression of CYP1A2 protein
[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein; [Paraquat co-treated with Maneb] results in increased expression of CYP1A2 mRNA; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP1A2 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP1A2 protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CYP1A2 mRNA]; Paraquat results in increased expression of and results in increased activity of CYP1A2 protein; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP1A2 mRNA]; Silymarin inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP1A2 protein]; Silymarin inhibits the reaction [Paraquat results in increased expression of CYP1A2 mRNA]
CTD PMID:20888808, PMID:23159886 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 increases expression ISO Paraquat results in increased expression of CYP26B1 mRNA CTD PMID:21371552 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases expression EXP Paraquat results in decreased expression of CYP2C6V1 mRNA CTD PMID:16328009 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions
decreases expression
ISO Ketoconazole inhibits the reaction [Paraquat results in decreased expression of CYP2D22 protein]; resveratrol inhibits the reaction [Paraquat results in decreased expression of CYP2D22 protein] CTD PMID:22334051 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases expression
increases activity
ISO
EXP
[Maneb co-treated with Paraquat] results in increased expression of CYP2E1 mRNA; [Paraquat co-treated with Maneb] results in increased activity of CYP2E1 protein; [Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA; Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased activity of CYP2E1 protein]; Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased activity of CYP2E1 protein]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]
Paraquat results in increased expression of CYP2E1 mRNA; Paraquat results in increased expression of CYP2E1 protein
[Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein; [Maneb co-treated with Paraquat] results in increased expression of CYP2E1 mRNA; Acetylcysteine inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP2E1 protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CYP2E1 mRNA]; Paraquat promotes the reaction [Zinc Sulfate results in increased expression of CYP2E1 mRNA]; Paraquat results in increased expression of and results in increased activity of CYP2E1 protein; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]; Silymarin inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP2E1 protein]; Silymarin inhibits the reaction [Paraquat results in increased expression of CYP2E1 mRNA]; Zinc Sulfate promotes the reaction [Paraquat results in increased expression of CYP2E1 mRNA]
Paraquat results in increased activity of CYP2E1 protein
CTD PMID:16510128, PMID:20553223, PMID:20888808, PMID:20964710, PMID:23159886 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 increases expression EXP Paraquat results in increased expression of CYP2F4 mRNA CTD PMID:16328009 NCBI chr 1:83,933,974...83,947,804
Ensembl chr 1:83,933,942...83,947,821
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 increases expression ISO Paraquat results in increased expression of CYP2J9 mRNA CTD PMID:21371552 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression
EXP betanin inhibits the reaction [Paraquat results in increased expression of CYP3A2 mRNA] CTD PMID:24799198 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 increases expression ISO Paraquat results in increased expression of CYP46A1 mRNA CTD PMID:27788593 NCBI chr 6:132,242,328...132,273,788
Ensembl chr 6:132,242,328...132,273,787
JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 decreases expression EXP Paraquat results in decreased expression of CYP4A3 mRNA CTD PMID:17077588 NCBI chr 5:134,468,666...134,484,851
Ensembl chr 5:134,469,270...134,484,839
JBrowse link
G Cyth3 cytohesin 3 increases expression ISO Paraquat results in increased expression of CYTH3 mRNA CTD PMID:12595580 NCBI chr12:12,877,559...12,907,771
Ensembl chr12:12,877,559...12,945,192
JBrowse link
G Daam2 dishevelled associated activator of morphogenesis 2 decreases expression ISO Paraquat results in decreased expression of DAAM2 mRNA CTD PMID:28619522 NCBI chr 9:13,444,883...13,493,154
Ensembl chr 9:13,446,896...13,490,669
JBrowse link
G Dap3 death associated protein 3 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of DAP3 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of DAP3 mRNA] CTD PMID:23963992 NCBI chr 2:188,225,607...188,255,324
Ensembl chr 2:188,225,613...188,252,725
JBrowse link
G Dapk1 death associated protein kinase 1 increases expression ISO Paraquat results in increased expression of DAPK1 mRNA CTD PMID:18836921 NCBI chr17:4,297,038...4,454,941
Ensembl chr17:4,297,224...4,454,778
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of DBI mRNA CTD PMID:18386188 NCBI chr13:36,147,667...36,156,076
Ensembl chr13:36,117,119...36,174,908
JBrowse link
G Dbp D-box binding PAR bZIP transcription factor increases expression ISO Paraquat results in increased expression of DBP mRNA CTD PMID:26345256 NCBI chr 1:101,687,896...101,692,845
Ensembl chr 1:101,687,855...101,692,846
JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 increases expression EXP Paraquat results in increased expression of DDAH1 mRNA CTD PMID:20388547 NCBI chr 2:251,634,368...251,766,009
Ensembl chr 2:251,634,431...251,766,014
JBrowse link
G Ddah2 dimethylarginine dimethylaminohydrolase 2 increases expression EXP Paraquat results in increased expression of DDAH2 mRNA CTD PMID:20388547 NCBI chr20:5,049,260...5,052,573
Ensembl chr20:5,049,496...5,052,585
JBrowse link
G Ddb2 damage specific DNA binding protein 2 increases expression ISO Paraquat results in increased expression of DDB2 mRNA CTD PMID:23613995 NCBI chr 3:80,030,437...80,052,984
Ensembl chr 3:80,030,437...80,052,953
JBrowse link
G Ddc dopa decarboxylase decreases expression ISO Paraquat results in decreased expression of DDC mRNA CTD PMID:21371552 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO
EXP
Paraquat results in increased expression of DDIT3 mRNA; Paraquat results in increased expression of DDIT3 protein
Minocycline inhibits the reaction [Paraquat results in increased expression of DDIT3 protein]; NFE2L2 mutant form inhibits the reaction [Paraquat results in increased expression of DDIT3 mRNA]; NFE2L2 mutant form inhibits the reaction [Paraquat results in increased expression of DDIT3 protein]
EIF2S1 protein promotes the reaction [salubrinal inhibits the reaction [Paraquat results in increased expression of DDIT3 protein]]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Paraquat results in increased expression of DDIT3 protein]; salubrinal inhibits the reaction [Paraquat results in increased expression of DDIT3 protein]
CTD PMID:19735704, PMID:20883675, PMID:22245251, PMID:22678742, PMID:23613995, PMID:27442881, PMID:28986289, PMID:30185695 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO Paraquat results in increased expression of DDIT4 mRNA CTD PMID:23613995 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked multiple interactions
decreases expression
ISO 6-bromoindirubin-3'-oxime promotes the reaction [Paraquat inhibits the reaction [TNFRSF10B protein binds to DDX3X protein]]; 6-bromoindirubin-3'-oxime promotes the reaction [Paraquat results in decreased expression of DDX3X protein modified form]; Paraquat inhibits the reaction [TNFRSF10B protein binds to DDX3X protein] CTD PMID:28414160 NCBI chr  X:10,400,363...10,414,010
Ensembl chr  X:10,400,366...10,413,995
JBrowse link
G Ddx5 DEAD-box helicase 5 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of DDX5 mRNA CTD PMID:18386188 NCBI chr10:94,979,759...94,988,461
Ensembl chr10:94,980,928...94,988,461
JBrowse link
G Dffa DNA fragmentation factor subunit alpha increases expression ISO Paraquat results in increased expression of DFFA mRNA CTD PMID:18836921 NCBI chr 5:165,922,893...165,935,822
Ensembl chr 5:165,922,915...165,935,821
JBrowse link
G Dgkb diacylglycerol kinase, beta decreases expression ISO Paraquat results in decreased expression of DGKB mRNA CTD PMID:21371552 NCBI chr 6:57,516,351...58,277,385
Ensembl chr 6:57,516,713...58,277,279
JBrowse link
G Dgkh diacylglycerol kinase, eta increases expression ISO Paraquat results in increased expression of DGKH mRNA CTD PMID:22563483 NCBI chr15:60,791,574...60,967,236
Ensembl chr15:60,803,098...60,959,769
JBrowse link
G Dgki diacylglycerol kinase, iota increases expression
multiple interactions
ISO Paraquat results in increased expression of DGKI mRNA
[Paraquat co-treated with Maneb] affects the expression of DGKI mRNA
CTD PMID:22563483 NCBI chr 4:64,365,115...64,831,473
Ensembl chr 4:64,374,342...64,831,473
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO Paraquat results in decreased expression of DHCR24 mRNA CTD PMID:23315990 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression EXP Paraquat results in decreased expression of DHCR7 mRNA CTD PMID:16328009 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein multiple interactions
increases transport
affects localization
increases expression
EXP
ISO
Cyclosporine inhibits the reaction [Paraquat affects the localization of DIABLO protein]; Dibucaine inhibits the reaction [Paraquat affects the localization of DIABLO protein]; diphenyleneiodonium inhibits the reaction [Paraquat affects the localization of DIABLO protein]; epigallocatechin gallate inhibits the reaction [Paraquat results in increased expression of DIABLO protein]
Paraquat results in increased transport of DIABLO protein
LGK974 inhibits the reaction [Paraquat results in increased transport of DIABLO protein]
CTD PMID:17936647, PMID:22245251, PMID:25947082, PMID:30205152 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330
JBrowse link
G Dip2b disco-interacting protein 2 homolog B multiple interactions
increases expression
ISO [Paraquat co-treated with Maneb] affects the expression of DIP2B mRNA
Paraquat results in increased expression of DIP2B mRNA
CTD PMID:22563483 NCBI chr 7:141,702,034...141,878,945
Ensembl chr 7:141,702,038...141,879,951
JBrowse link
G Dld dihydrolipoamide dehydrogenase decreases expression ISO Paraquat results in decreased expression of DLD mRNA CTD PMID:21371552 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694
JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 multiple interactions
decreases expression
EXP Estradiol inhibits the reaction [Paraquat results in decreased expression of DLG4 protein] CTD PMID:31715309 NCBI chr10:56,625,845...56,655,543
Ensembl chr10:56,627,411...56,653,599
JBrowse link
G Dll1 delta like canonical Notch ligand 1 multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of DLL1 mRNA CTD PMID:23017109 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379
JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of DLST protein; Minocycline inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of DLST protein]; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of DLST protein] CTD PMID:23562983 NCBI chr 6:108,936,534...108,961,322
Ensembl chr 6:108,936,664...108,959,803
JBrowse link
G Dmd dystrophin increases response to substance ISO DMD gene mutant form results in increased susceptibility to Paraquat CTD PMID:10797403 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259
JBrowse link
G Dmrta2 DMRT-like family A2 decreases expression
multiple interactions
ISO Paraquat results in decreased expression of DMRTA2 mRNA
[Paraquat co-treated with Maneb] affects the expression of DMRTA2 mRNA
CTD PMID:22563483 NCBI chr 5:129,754,295...129,760,045
Ensembl chr 5:129,756,149...129,758,986
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 decreases response to substance ISO DNAJB1 protein results in decreased susceptibility to Paraquat CTD PMID:11359866 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of DNAJB6 mRNA CTD PMID:18386188 NCBI chr 4:2,711,329...2,774,969
Ensembl chr 4:2,711,385...2,774,890
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 decreases expression ISO Paraquat results in decreased expression of DNAJC3 mRNA CTD PMID:16797015 NCBI chr15:104,186,918...104,226,236
Ensembl chr15:104,186,792...104,226,329
JBrowse link
G Dnm1l dynamin 1-like increases expression ISO Paraquat results in increased expression of DNM1L protein CTD PMID:28215578 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198
JBrowse link
G Dnm2 dynamin 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of DNM2 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of DNM2 mRNA] CTD PMID:23963992 NCBI chr 8:22,458,869...22,540,649
Ensembl chr 8:22,458,899...22,540,524
JBrowse link
G Dok4 docking protein 4 increases expression ISO Paraquat results in increased expression of DOK4 mRNA CTD PMID:21371552 NCBI chr19:10,563,423...10,574,094
Ensembl chr19:10,563,423...10,574,093
JBrowse link
G Drd2 dopamine receptor D2 affects expression
increases expression
multiple interactions
EXP
ISO
Paraquat affects the expression of DRD2 mRNA
Paraquat results in increased expression of DRD2 mRNA
[SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of DRD2 mRNA
CTD PMID:15206577, PMID:18198484, PMID:23017109 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Drd4 dopamine receptor D4 affects expression
multiple interactions
EXP
ISO
Paraquat affects the expression of DRD4 mRNA
[Paraquat co-treated with Maneb] results in increased expression of DRD4 protein
CTD PMID:15206577, PMID:22563483 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483
JBrowse link
G Drd5 dopamine receptor D5 multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of DRD5 mRNA CTD PMID:23017109 NCBI chr14:77,220,579...77,222,006
Ensembl chr14:77,220,579...77,222,006
JBrowse link
G Dtx1 deltex E3 ubiquitin ligase 1 affects expression ISO Paraquat affects the expression of DTX1 mRNA CTD PMID:24053911 NCBI chr12:41,383,885...41,415,783
Ensembl chr12:41,385,241...41,414,754
JBrowse link
G Duox1 dual oxidase 1 multiple interactions
increases expression
ISO APOD protein affects the reaction [Paraquat results in increased expression of DUOX1 mRNA]
kaempferol inhibits the reaction [Paraquat results in increased expression of DUOX1 mRNA]
CTD PMID:21688324, PMID:25177032 NCBI chr 3:114,251,794...114,286,827
Ensembl chr 3:114,253,637...114,286,802
JBrowse link
G Duox2 dual oxidase 2 multiple interactions ISO [Quercetin co-treated with Paraquat] results in increased expression of DUOX2 mRNA CTD PMID:22996356 NCBI chr 3:114,218,187...114,237,808
Ensembl chr 3:114,218,193...114,235,933
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Paraquat results in increased expression of DUSP1 mRNA CTD PMID:12595580, PMID:23315990, PMID:28012437 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dvl2 dishevelled segment polarity protein 2 decreases expression
multiple interactions
EXP
ISO
Paraquat results in decreased expression of DVL2 mRNA
Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of DVL2 protein]
WNT1 protein inhibits the reaction [Paraquat results in decreased expression of DVL2 mRNA]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of DVL2 protein]
Paraquat results in decreased expression of DVL2 mRNA; Paraquat results in decreased expression of DVL2 protein
CTD PMID:26887261, PMID:27788593, PMID:30171970 NCBI chr10:56,609,810...56,619,269
Ensembl chr10:56,610,051...56,619,269
JBrowse link
G Dynll1 dynein light chain LC8-type 1 decreases expression
increases expression
ISO
EXP
Paraquat results in decreased expression of DYNLL1 mRNA
Paraquat results in increased expression of DYNLL1 mRNA
CTD PMID:12595580, PMID:16328009, PMID:20388547 NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572
JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A increases expression ISO Paraquat results in increased expression of DYRK1A mRNA CTD PMID:21371552 NCBI chr11:34,858,339...34,958,733
Ensembl chr11:34,865,532...34,956,536
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of E2F1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of E2F1 mRNA] CTD PMID:23963992 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 multiple interactions
increases expression
ISO salubrinal inhibits the reaction [Paraquat results in increased expression of EDEM1 protein] CTD PMID:19735704 NCBI chr 4:140,886,644...140,918,654
Ensembl chr 4:140,886,545...140,915,779
JBrowse link
G Edn1 endothelin 1 multiple interactions
increases expression
EXP
ISO
green tea extract AR25 inhibits the reaction [Paraquat results in increased expression of EDN1 mRNA]; green tea extract AR25 inhibits the reaction [Paraquat results in increased expression of EDN1 protein]
Acetylcysteine inhibits the reaction [Paraquat results in increased expression of EDN1 mRNA]; Dapsone inhibits the reaction [Paraquat results in increased expression of EDN1 mRNA]
Paraquat results in increased expression of EDN1 mRNA; Paraquat results in increased expression of EDN1 protein
CTD PMID:17235729, PMID:21765237 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ednra endothelin receptor type A affects expression EXP Paraquat affects the expression of EDNRA mRNA CTD PMID:16854511 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of EEF1A1 mRNA CTD PMID:18386188 NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818
JBrowse link
G Eef1a2 eukaryotic translation elongation factor 1 alpha 2 decreases expression ISO Paraquat results in decreased expression of EEF1A2 mRNA CTD PMID:21371552 NCBI chr 3:176,657,104...176,666,282
Ensembl chr 3:176,657,107...176,666,282
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of EEF1G mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of EEF1G mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of EEF1G mRNA] CTD PMID:23963992 NCBI chr 1:225,163,391...225,173,997
Ensembl chr 1:225,163,391...225,173,995
JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase decreases expression ISO Paraquat results in decreased expression of EEF2K mRNA CTD PMID:28012437 NCBI chr 1:190,780,211...190,839,926
Ensembl chr 1:190,780,236...190,842,324
JBrowse link
G Efnb1 ephrin B1 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of EFNB1 mRNA CTD PMID:23017109 NCBI chr  X:68,891,227...68,904,034
Ensembl chr  X:68,891,227...68,904,038
JBrowse link
G Egfr epidermal growth factor receptor decreases expression EXP Paraquat results in decreased expression of EGFR protein CTD PMID:17298174 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egln2 egl-9 family hypoxia-inducible factor 2 decreases expression ISO Paraquat results in decreased expression of EGLN2 mRNA CTD PMID:21371552 NCBI chr 1:83,969,456...83,977,665
Ensembl chr 1:83,969,457...83,977,236
JBrowse link
G Egr1 early growth response 1 increases expression ISO Paraquat results in increased expression of EGR1 mRNA CTD PMID:20883675 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Egr4 early growth response 4 multiple interactions
decreases expression
ISO [Paraquat co-treated with Maneb] affects the expression of EGR4 mRNA
Paraquat results in decreased expression of EGR4 mRNA
CTD PMID:22563483 NCBI chr 4:117,293,620...117,296,082
Ensembl chr 4:117,293,620...117,296,082
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases phosphorylation ISO Paraquat results in increased phosphorylation of EIF2A protein CTD PMID:20929985 NCBI chr 2:148,722,343...148,755,781
Ensembl chr 2:148,722,231...148,755,520
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation
increases expression
EXP
ISO
Paraquat results in increased phosphorylation of EIF2AK3 protein
Paraquat results in increased expression of EIF2AK3 protein modified form
CTD PMID:22245251, PMID:27442881, PMID:28986289 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation
multiple interactions
increases expression
EXP
ISO
Paraquat results in increased phosphorylation of EIF2S1 protein
EIF2S1 protein promotes the reaction [salubrinal inhibits the reaction [Paraquat results in increased expression of DDIT3 protein]]; EIF2S1 protein promotes the reaction [salubrinal inhibits the reaction [Paraquat results in increased expression of HSPA5 protein]]; salubrinal promotes the reaction [Paraquat results in increased expression of EIF2S1 protein modified form]
CTD PMID:22245251, PMID:27442881, PMID:28986289 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression ISO Paraquat results in increased expression of EIF4EBP1 mRNA CTD PMID:12595580 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of EIF4G2 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of EIF4G2 mRNA] CTD PMID:23963992 NCBI chr 1:175,883,362...175,895,510
Ensembl chr 1:175,883,363...175,895,510
JBrowse link
G Elavl1 ELAV like RNA binding protein 1 affects localization ISO Paraquat affects the localization of ELAVL1 protein CTD PMID:22879928 NCBI chr12:2,461,502...2,502,432
Ensembl chr12:2,461,502...2,502,432
JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of ELK1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ELK1 mRNA] CTD PMID:23963992 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822
JBrowse link
G Eln elastin increases expression ISO Paraquat results in increased expression of ELN mRNA CTD PMID:17215068, PMID:26345256 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863
JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 increases expression ISO Paraquat results in increased expression of ELP1 mRNA CTD PMID:21371552 NCBI chr 5:73,503,406...73,552,798
Ensembl chr 5:73,503,407...73,552,798
JBrowse link
G Eno1 enolase 1 multiple interactions
decreases expression
ISO [Maneb co-treated with Paraquat] results in increased expression of ENO1 protein; [Paraquat co-treated with Maneb] results in decreased expression of ENO1 mRNA; [Paraquat co-treated with Maneb] results in decreased expression of ENO1 protein; Minocycline inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of ENO1 protein]
Paraquat results in decreased expression of ENO1 mRNA; Paraquat results in decreased expression of ENO1 protein
CTD PMID:17532186, PMID:18386188, PMID:23562983, PMID:27111068 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Eno2 enolase 2 increases expression
multiple interactions
decreases expression
ISO
EXP
Paraquat results in increased expression of ENO2 mRNA alternative form
[Maneb co-treated with Paraquat] results in increased expression of ENO2 protein
Paraquat results in decreased expression of ENO2 protein
CTD PMID:17064354, PMID:18198484, PMID:23562983, PMID:24521700 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Epn2 epsin 2 increases expression ISO Paraquat results in increased expression of EPN2 mRNA CTD PMID:21371552 NCBI chr10:47,795,496...47,857,373
Ensembl chr10:47,795,524...47,857,326
JBrowse link
G Epo erythropoietin multiple interactions ISO EPO protein inhibits the reaction [SOD2 gene mutant form results in increased susceptibility to Paraquat] CTD PMID:16288465 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 decreases expression ISO Paraquat results in decreased expression of EPS8 mRNA CTD PMID:21371552 NCBI chr 4:171,475,155...171,645,620
Ensembl chr 4:171,475,567...171,591,882
JBrowse link
G Epx eosinophil peroxidase multiple interactions
decreases expression
ISO APOD protein affects the reaction [Paraquat results in decreased expression of EPX mRNA] CTD PMID:21688324 NCBI chr10:75,160,690...75,171,774
Ensembl chr10:75,160,690...75,171,774
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions
decreases response to substance
ISO NFE2L2 protein affects the reaction [ERBB2 protein results in decreased susceptibility to Paraquat] CTD PMID:25467193 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728
JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 decreases expression ISO Paraquat results in decreased expression of ERBB3 mRNA CTD PMID:16797015 NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350
JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 increases expression ISO Paraquat results in increased expression of ERBB4 mRNA CTD PMID:22563483 NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644
JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit affects splicing ISO Paraquat affects the splicing of ERCC1 mRNA CTD PMID:23613995 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor increases response to substance ISO ERCC6 gene mutant form results in increased susceptibility to Paraquat CTD PMID:12509265, PMID:15340056 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610
JBrowse link
G Ergic2 ERGIC and golgi 2 decreases expression
increases expression
ISO Paraquat results in decreased expression of ERGIC2 mRNA
Paraquat results in increased expression of ERGIC2 mRNA
CTD PMID:21371552 NCBI chr 4:182,569,086...182,600,258
Ensembl chr 4:182,569,089...182,600,258
JBrowse link
G Ermp1 endoplasmic reticulum metallopeptidase 1 increases expression ISO Paraquat results in increased expression of ERMP1 mRNA CTD PMID:21371552 NCBI chr 1:247,784,830...247,821,771
Ensembl chr 1:247,787,582...247,821,728
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases expression
increases phosphorylation
ISO
EXP
Paraquat promotes the reaction [MAP3K5 protein results in increased phosphorylation of ERN1 protein]
Paraquat results in increased expression of ERN1 protein modified form
Paraquat results in increased phosphorylation of ERN1 protein
CTD PMID:20929985, PMID:22245251, PMID:28986289 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Esr1 estrogen receptor 1 decreases activity EXP Paraquat results in decreased activity of ESR1 protein CTD PMID:31715309 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esrra estrogen related receptor, alpha decreases expression ISO Paraquat results in decreased expression of ESRRA mRNA CTD PMID:12595580 NCBI chr 1:222,168,729...222,178,842
Ensembl chr 1:222,168,730...222,178,725
JBrowse link
G Etl4 enhancer trap locus 4 increases expression
multiple interactions
ISO Paraquat results in increased expression of ETL4 mRNA
[Paraquat co-treated with Maneb] affects the expression of ETL4 mRNA
CTD PMID:22563483 NCBI chr17:87,173,265...87,681,268
Ensembl chr17:87,274,944...87,681,317
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor decreases expression EXP Paraquat results in decreased expression of ETS1 mRNA CTD PMID:18198484 NCBI chr 8:33,756,634...33,879,625
Ensembl chr 8:33,816,386...33,879,625
JBrowse link
G F2 coagulation factor II increases expression EXP Paraquat results in increased expression of F2 mRNA CTD PMID:18198484 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031
JBrowse link
G Faah fatty acid amide hydrolase increases expression EXP Paraquat results in increased expression of FAAH mRNA CTD PMID:18198484 NCBI chr 5:134,852,899...134,872,095
Ensembl chr 5:134,852,875...134,871,775
JBrowse link
G Fabp5 fatty acid binding protein 5 increases expression ISO Paraquat results in increased expression of FABP5 mRNA CTD PMID:21371552 NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378
JBrowse link
G Fadd Fas associated via death domain decreases expression ISO Paraquat results in decreased expression of FADD mRNA CTD PMID:18836921 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression ISO Paraquat results in decreased expression of FADS2 mRNA CTD PMID:21371552 NCBI chr 1:225,906,582...226,152,568
Ensembl chr 1:226,114,413...226,152,524
JBrowse link
G Fanca FA complementation group A multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of FANCA mRNA CTD PMID:28012437 NCBI chr19:56,067,548...56,126,075
Ensembl chr19:56,067,548...56,126,063
JBrowse link
G Fancb FA complementation group B multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of FANCB mRNA CTD PMID:28012437 NCBI chr  X:31,124,018...31,140,790
Ensembl chr  X:31,124,018...31,140,711
JBrowse link
G Fancd2 FA complementation group D2 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of FANCD2 mRNA CTD PMID:28012437 NCBI chr 4:145,489,869...145,551,479
Ensembl chr 4:145,489,869...145,551,479
JBrowse link
G Fas Fas cell surface death receptor increases expression
multiple interactions
ISO Paraquat results in increased expression of FAS mRNA
[Maneb co-treated with Paraquat] results in increased expression of FAS mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of FAS mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of FAS mRNA]
CTD PMID:18836921, PMID:23963992 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand increases expression ISO Paraquat results in increased expression of FASL mRNA
Paraquat results in increased expression of FASLG mRNA
CTD PMID:9657385, PMID:17215068, PMID:18836921 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fat3 FAT atypical cadherin 3 increases expression ISO Paraquat results in increased expression of FAT3 mRNA CTD PMID:22563483 NCBI chr 8:14,417,039...15,011,596
Ensembl chr 8:14,417,584...14,880,644
JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of FEZ1 mRNA CTD PMID:23017109 NCBI chr 8:39,305,128...39,350,270
Ensembl chr 8:39,305,128...39,350,270
JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression ISO Paraquat results in increased expression of FGF1 mRNA CTD PMID:16324872 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824
JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression
decreases secretion
multiple interactions
EXP
ISO
Paraquat results in increased expression of FGF2 mRNA
Paraquat results in decreased secretion of FGF2 protein
Oxygen inhibits the reaction [Paraquat results in increased expression of FGF2 mRNA]
CTD PMID:18198484, PMID:26722498, PMID:30698896 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of FGFR3 mRNA; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of FGFR3 mRNA] CTD PMID:23963992 NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706
JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 multiple interactions
affects response to substance
ISO [Paraquat co-treated with Maneb] results in decreased expression of FKBP4 mRNA
FKBP4 protein affects the susceptibility to Paraquat
CTD PMID:18386188, PMID:20713718 NCBI chr 4:161,748,993...161,757,447
Ensembl chr 4:161,748,993...161,757,447
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 increases expression
multiple interactions
affects expression
ISO
EXP
Paraquat results in increased expression of FKBP5 mRNA
[Paraquat co-treated with Maneb] results in decreased expression of FKBP5 mRNA
Paraquat affects the expression of FKBP5 mRNA
CTD PMID:12595580, PMID:16854511, PMID:18386188 NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020
JBrowse link
G Fn1 fibronectin 1 decreases expression
increases expression
multiple interactions
ISO
EXP
Paraquat results in decreased expression of FN1 mRNA
Paraquat results in increased expression of FN1 protein
Paraquat results in increased expression of FN1 mRNA; Paraquat results in increased expression of FN1 protein
prolinedithiocarbamate inhibits the reaction [Paraquat results in increased expression of FN1 mRNA]
CTD PMID:16797015, PMID:17215068, PMID:23803522, PMID:25873302, PMID:26345256, PMID:29495171 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO
EXP
[Maneb co-treated with Paraquat] results in increased expression of FOS mRNA; Paraquat promotes the reaction [JUN protein binds to FOS protein]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of FOS mRNA]
[Paraquat co-treated with Maneb] results in decreased expression of FOS mRNA; [Paraquat co-treated with Maneb] results in decreased expression of FOS protein
[Paraquat co-treated with SOD2 protein] results in increased expression of FOS mRNA
Paraquat results in increased expression of FOS mRNA
CTD PMID:10464329, PMID:11728812, PMID:17048122, PMID:23963992, PMID:27460631 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxm1 forkhead box M1 decreases expression ISO Paraquat results in decreased expression of FOXM1 mRNA CTD PMID:23315990 NCBI chr 4:161,685,236...161,697,633
Ensembl chr 4:161,685,258...161,696,305
JBrowse link
G Foxo3 forkhead box O3 multiple interactions
affects expression
increases response to substance
ISO FOXO3 mutant form inhibits the reaction [Paraquat results in increased expression of BCL2L11 mRNA]
Paraquat affects the expression of FOXO3 mRNA
FOXO3 protein results in increased susceptibility to Paraquat
CTD PMID:23620592, PMID:29287252 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Fstl1 follistatin-like 1 multiple interactions
increases expression
ISO plant extract, Puerariae Radix inhibits the reaction [Paraquat results in increased expression of FSTL1 mRNA]; plant extract, Puerariae Radix inhibits the reaction [Paraquat results in increased expression of FSTL1 protein]
Paraquat results in increased expression of FSTL1 mRNA; Paraquat results in increased expression of FSTL1 protein
CTD PMID:26758514 NCBI chr11:65,791,196...65,845,721
Ensembl chr11:65,782,567...65,845,418
JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions
increases expression
ISO Paraquat promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]
Paraquat results in increased expression of FTL1 mRNA; Paraquat results in increased expression of FTL1 protein
CTD PMID:12644586, PMID:28542246 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G Ftmt ferritin mitochondrial multiple interactions ISO Paraquat promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]] CTD PMID:12644586 NCBI chr18:47,294,292...47,295,541
Ensembl chr18:47,294,292...47,295,541
JBrowse link
G Fut2 fucosyltransferase 2 increases expression EXP Paraquat results in increased expression of FUT2 mRNA CTD PMID:17077588 NCBI chr 1:101,631,633...101,651,668
Ensembl chr 1:101,631,635...101,651,668
JBrowse link
G Fxyd6 FXYD domain-containing ion transport regulator 6 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of FXYD6 mRNA CTD PMID:18386188 NCBI chr 8:49,676,520...49,703,419
Ensembl chr 8:49,676,540...49,703,419
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions
affects expression
increases activity
EXP FYN protein affects the reaction [Paraquat results in decreased expression of PDGFRA protein]
Paraquat affects the expression of FYN mRNA
Paraquat results in increased activity of FYN protein
CTD PMID:15206577, PMID:17298174 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317
JBrowse link
G Fzd1 frizzled class receptor 1 decreases expression
multiple interactions
EXP
ISO
Paraquat results in decreased expression of FZD1 mRNA
Paraquat results in decreased expression of FZD1 mRNA; Paraquat results in decreased expression of FZD1 protein
WNT1 protein inhibits the reaction [Paraquat results in decreased expression of FZD1 mRNA]
CTD PMID:26887261, PMID:30171970 NCBI chr 4:26,470,864...26,475,262
Ensembl chr 4:26,470,864...26,475,262
JBrowse link
G Fzd4 frizzled class receptor 4 decreases expression
multiple interactions
ISO Paraquat results in decreased expression of FZD4 mRNA
WNT1 protein inhibits the reaction [Paraquat results in decreased expression of FZD4 mRNA]
Paraquat results in decreased expression of FZD4 mRNA; Paraquat results in decreased expression of FZD4 protein
CTD PMID:28619522, PMID:30171970 NCBI chr 1:153,589,471...153,598,376
Ensembl chr 1:153,589,471...153,598,375
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases activity EXP Paraquat results in increased activity of G6PDX protein CTD PMID:10699569 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gab1 GRB2-associated binding protein 1 decreases expression
multiple interactions
ISO Paraquat results in decreased expression of GAB1 mRNA
APOD protein affects the reaction [Paraquat results in decreased expression of GAB1 mRNA]
CTD PMID:21688324 NCBI chr19:30,794,290...30,903,819
Ensembl chr19:30,794,571...30,902,008
JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 increases expression ISO Paraquat results in increased expression of GABARAPL1 mRNA CTD PMID:12595580 NCBI chr 4:163,293,724...163,302,866
Ensembl chr 4:163,293,724...163,302,858
JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 decreases expression ISO
EXP
Paraquat results in decreased expression of GABBR1 mRNA
Paraquat results in decreased expression of GABBR1 protein
CTD PMID:21371552, PMID:24521700 NCBI chr20:1,955,344...1,984,907
Ensembl chr20:1,955,359...1,984,863
JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 increases expression EXP Paraquat results in increased expression of GABRA4 mRNA CTD PMID:18198484 NCBI chr14:39,154,072...39,230,994
Ensembl chr14:39,154,529...39,231,695
JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of GABRA6 mRNA CTD PMID:22563483 NCBI chr10:27,847,447...27,862,896
Ensembl chr10:27,847,439...27,862,868
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 decreases expression EXP Paraquat results in decreased expression of GABRB1 mRNA CTD PMID:18198484 NCBI chr14:38,631,192...39,112,598
Ensembl chr14:38,643,385...39,112,600
JBrowse link
G Gabrd gamma-aminobutyric acid type A receptor subunit delta decreases expression EXP Paraquat results in decreased expression of GABRD mRNA CTD PMID:19146868 NCBI chr 5:172,797,478...172,809,374
Ensembl chr 5:172,797,450...172,809,353
JBrowse link
G Gad1 glutamate decarboxylase 1 decreases expression EXP Paraquat results in decreased expression of GAD1 mRNA CTD PMID:17493592 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157
JBrowse link
G Gad2 glutamate decarboxylase 2 decreases expression EXP Paraquat results in decreased expression of GAD2 mRNA; Paraquat results in decreased expression of GAD2 protein CTD PMID:18198484, PMID:24521700 NCBI chr17:89,171,576...89,234,770
Ensembl chr17:89,171,250...89,238,040
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions
increases expression
ISO
EXP
GPX1 protein affects the reaction [Paraquat affects the expression of GADD45A mRNA]
Paraquat results in increased expression of GADD45A mRNA
CTD PMID:12595580, PMID:12654481, PMID:15246999, PMID:17935786, PMID:18836921, PMID:19526292, PMID:20883675 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO Paraquat results in increased expression of GADD45B mRNA CTD PMID:12595580, PMID:15246999 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322
JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression ISO Paraquat results in increased expression of GADD45G mRNA CTD PMID:12595580, PMID:15246999 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243
JBrowse link
G Gak cyclin G associated kinase increases expression EXP Paraquat results in increased expression of GAK mRNA CTD PMID:18198484 NCBI chr14:2,100,104...2,174,332
Ensembl chr14:2,100,106...2,174,318
JBrowse link
G Gap43 growth associated protein 43 increases expression EXP Paraquat results in increased expression of GAP43 mRNA CTD PMID:18198484 NCBI chr11:58,624,198...58,717,916
Ensembl chr11:58,624,198...58,717,914
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions
affects localization
EXP [7-nitroindazole results in decreased chemical synthesis of Nitric Oxide] inhibits the reaction [Paraquat affects the localization of GAPDH protein]; Selegiline inhibits the reaction [Paraquat affects the localization of GAPDH protein] CTD PMID:20478973 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase increases expression
decreases expression
ISO Paraquat results in increased expression of GART mRNA
Paraquat results in decreased expression of GART mRNA
CTD PMID:21371552 NCBI chr11:31,780,477...31,805,728
Ensembl chr11:31,780,487...31,805,728
JBrowse link
G Gas5 growth arrest specific 5 multiple interactions
decreases expression
ISO [Paraquat co-treated with Maneb] results in decreased expression of GAS5 mRNA
Paraquat results in decreased expression of GAS5 mRNA
CTD PMID:18386188, PMID:26824344 NCBI chr13:78,852,523...78,855,844 JBrowse link
G Gast gastrin increases expression EXP Paraquat results in increased expression of GAST mRNA CTD PMID:18198484 NCBI chr10:88,245,532...88,248,485
Ensembl chr10:88,245,532...88,248,484
JBrowse link
G Gata3 GATA binding protein 3 decreases expression ISO Paraquat results in decreased expression of GATA3 CTD PMID:25496228 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Gcgr glucagon receptor decreases expression EXP Paraquat results in decreased expression of GCGR mRNA CTD PMID:17077588 NCBI chr10:109,707,863...109,716,253
Ensembl chr10:109,707,962...109,716,128
JBrowse link
G Gch1 GTP cyclohydrolase 1 increases expression EXP Paraquat results in increased expression of GCH1 mRNA CTD PMID:20388547 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
decreases expression
multiple interactions
affects expression
ISO
EXP
Paraquat results in increased expression of GCLC mRNA
Paraquat results in decreased expression of GCLC mRNA; Paraquat results in decreased expression of GCLC protein
[alpha-Tocopherol co-treated with Paraquat] results in increased expression of GCLC mRNA; Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of GCLC protein]; CAT protein inhibits the reaction [Paraquat results in decreased expression of GCLC protein]; meloxicam inhibits the reaction [Paraquat results in decreased expression of GCLC protein]
Paraquat affects the expression of GCLC mRNA
CTD PMID:16854511, PMID:17215068, PMID:20851755, PMID:24530478, PMID:24866057, PMID:26598004, PMID:28467894 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases response to substance
decreases expression
increases expression
multiple interactions
ISO
EXP
GCLM gene mutant form results in increased susceptibility to Paraquat
Paraquat results in decreased expression of GCLM protein
Paraquat results in increased expression of GCLM mRNA
[alpha-Tocopherol co-treated with Paraquat] results in increased expression of GCLM mRNA
[GCLM gene mutant form results in increased susceptibility to Paraquat] which results in decreased abundance of Dopamine; [GCLM gene mutant form results in increased susceptibility to Paraquat] which results in decreased activity of ACO2 protein
CTD PMID:23704229, PMID:24530478, PMID:27993944, PMID:28467894 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Paraquat results in increased expression of GDF15 mRNA CTD PMID:20883675 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gdf3 growth differentiation factor 3 increases expression
multiple interactions
ISO Paraquat results in increased expression of GDF3 mRNA; Paraquat results in increased expression of GDF3 protein
Paraquat affects the reaction [Bucladesine affects the expression of GDF3 mRNA]; Paraquat affects the reaction [Bucladesine affects the expression of GDF3 protein]
CTD PMID:30698896, PMID:31400064 NCBI chr 4:155,417,667...155,422,014
Ensembl chr 4:155,417,004...155,421,998
JBrowse link
G Gdnf glial cell derived neurotrophic factor decreases response to substance
increases expression
multiple interactions
ISO GDNF protein results in decreased susceptibility to Paraquat
Paraquat results in increased expression of GDNF mRNA
APOD protein affects the reaction [Paraquat results in increased expression of GDNF mRNA]
CTD PMID:17935603, PMID:21688324, PMID:29454966 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions
affects expression
increases expression
ISO
EXP
[Paraquat co-treated with Maneb] results in increased expression of GFAP protein; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of GFAP protein]; APOD protein affects the reaction [Paraquat results in increased expression of GFAP protein]
Paraquat affects the expression of GFAP mRNA
Paraquat results in increased expression of GFAP mRNA; Paraquat results in increased expression of GFAP protein
[Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased expression of GFAP protein
CTD PMID:21688324, PMID:24376630, PMID:24521700, PMID:25314302, PMID:28467894, PMID:29454966, PMID:30698896, PMID:30797899 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Gfra1 GDNF family receptor alpha 1 increases expression EXP Paraquat results in increased expression of GFRA1 mRNA CTD PMID:17077588 NCBI chr 1:279,203,046...279,572,789 JBrowse link
G Gfra2 GDNF family receptor alpha 2 increases expression EXP Paraquat results in increased expression of GFRA2 mRNA CTD PMID:18198484 NCBI chr15:52,557,004...52,648,984
Ensembl chr15:52,557,607...52,648,972
JBrowse link
G Gh1 growth hormone 1 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of GH mRNA CTD PMID:22563483 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Ghr growth hormone receptor increases response to substance
affects response to substance
decreases response to substance
ISO GHR gene mutant form results in increased susceptibility to Paraquat
GHR protein affects the susceptibility to Paraquat
GHR gene mutant form results in decreased susceptibility to Paraquat
CTD PMID:12384824, PMID:15701676, PMID:16713617, PMID:19786089 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638
JBrowse link
G Ghrl ghrelin and obestatin prepropeptide multiple interactions ISO GHRL protein inhibits the reaction [Paraquat results in increased activity of CASP3 protein] CTD PMID:31381934 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066
JBrowse link
G Ghsr growth hormone secretagogue receptor decreases expression EXP Paraquat results in decreased expression of GHSR mRNA CTD PMID:17077588 NCBI chr 2:113,065,953...113,071,265
Ensembl chr 2:113,066,885...113,070,261
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression ISO Paraquat results in decreased expression of GJA1 mRNA CTD PMID:12595580 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gjb1 gap junction protein, beta 1 decreases expression ISO Paraquat results in decreased expression of GJB1 mRNA CTD PMID:16797015 NCBI chr  X:71,272,030...71,279,973
Ensembl chr  X:71,272,042...71,279,977
JBrowse link
G Glrx glutaredoxin increases response to substance
increases expression
ISO GLRX gene mutant form results in increased susceptibility to Paraquat
Paraquat results in increased expression of GLRX mRNA
CTD PMID:12732627, PMID:17893043 NCBI chr 2:2,606,032...2,615,944
Ensembl chr 2:2,605,996...2,615,944
JBrowse link
G Glrx2 glutaredoxin 2 decreases expression
increases expression
ISO Paraquat results in decreased expression of GLRX2 mRNA
Paraquat results in increased expression of GLRX2 mRNA
CTD PMID:12732627, PMID:21371552 NCBI chr13:60,529,057...60,552,115
Ensembl chr13:60,529,932...60,537,916
JBrowse link
G Gls glutaminase decreases activity EXP Paraquat results in decreased activity of GLS protein CTD PMID:28916328 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Glul glutamate-ammonia ligase multiple interactions
affects expression
decreases expression
increases expression
EXP
ISO
[Paraquat results in increased abundance of Reactive Oxygen Species] which results in decreased expression of GLUL protein; SB 203580 inhibits the reaction [[Paraquat results in increased abundance of Reactive Oxygen Species] which results in decreased expression of GLUL protein]
Paraquat affects the expression of GLUL mRNA
Paraquat results in decreased expression of GLUL protein
Paraquat results in increased expression of GLUL protein
CTD PMID:24376630, PMID:24521700, PMID:29454966 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229
JBrowse link
G Gm2a GM2 ganglioside activator multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of GM2A mRNA CTD PMID:18386188 NCBI chr10:40,438,394...40,450,927
Ensembl chr10:40,438,356...40,450,930
JBrowse link
G Gmfb glia maturation factor, beta multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of GMFB mRNA; [Paraquat co-treated with Maneb] results in decreased expression of GMFB protein CTD PMID:17532186 NCBI chr15:23,597,846...23,611,541
Ensembl chr15:23,601,368...23,606,634
JBrowse link
G Gnai3 G protein subunit alpha i3 increases expression EXP Paraquat results in increased expression of GNAI3 mRNA CTD PMID:17077588 NCBI chr 2:210,896,779...210,934,733
Ensembl chr 2:210,896,656...210,934,749
JBrowse link
G Gnao1 G protein subunit alpha o1 affects expression EXP Paraquat affects the expression of GNAO1 mRNA CTD PMID:15206577 NCBI chr19:11,513,201...11,669,578
Ensembl chr19:11,513,201...11,669,578
JBrowse link
G Gnas GNAS complex locus increases expression
affects expression
ISO
EXP
Paraquat results in increased expression of GNAS mRNA
Paraquat affects the expression of GNAS mRNA
CTD PMID:15206577, PMID:16797015 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483
JBrowse link
G Gng5 G protein subunit gamma 5 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of GNG5 mRNA CTD PMID:18386188 NCBI chr 2:252,359,976...252,368,473
Ensembl chr 2:252,359,976...252,368,473
JBrowse link
G Gngt2 G protein subunit gamma transducin 2 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of GNGT2 mRNA CTD PMID:22563483 NCBI chr10:83,654,321...83,658,601
Ensembl chr10:83,655,460...83,658,589
JBrowse link
G Gnrhr gonadotropin releasing hormone receptor decreases expression EXP Paraquat results in decreased expression of GNRHR mRNA CTD PMID:17077588 NCBI chr14:23,480,462...23,498,450
Ensembl chr14:23,480,462...23,498,450
JBrowse link
G Gopc golgi associated PDZ and coiled-coil motif containing increases expression ISO Paraquat results in increased expression of GOPC mRNA CTD PMID:21371552 NCBI chr20:33,471,355...33,521,281
Ensembl chr20:33,471,351...33,521,311
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 decreases activity
increases expression
EXP Paraquat results in decreased activity of GOT1 protein
Paraquat results in increased expression of GOT1 mRNA
CTD PMID:16555045, PMID:17481832 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 decreases expression ISO Paraquat results in decreased expression of GOT2 mRNA CTD PMID:21371552 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
G Gpc1 glypican 1 affects expression EXP Paraquat affects the expression of GPC1 mRNA CTD PMID:15206577 NCBI chr 9:99,998,275...100,026,818
Ensembl chr 9:99,998,275...100,026,818
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 increases expression EXP Paraquat results in increased expression of GPER1 mRNA CTD PMID:17077588 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Gpr27 G protein-coupled receptor 27 decreases expression
multiple interactions
ISO Paraquat results in decreased expression of GPR27 mRNA
[Paraquat co-treated with Maneb] affects the expression of GPR27 mRNA
CTD PMID:22563483 NCBI chr 4:132,137,793...132,138,926
Ensembl chr 4:132,137,793...132,138,926
JBrowse link
G Gpr6 G protein-coupled receptor 6 increases expression EXP Paraquat results in increased expression of GPR6 mRNA CTD PMID:17077588 NCBI chr20:45,813,169...45,815,940
Ensembl chr20:45,813,169...45,815,940
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases activity
ISO NME1 protein affects the reaction [Paraquat results in increased activity of GPT protein] CTD PMID:28077425 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression
affects expression
decreases expression
multiple interactions
decreases response to substance
increases response to substance
ISO
EXP
Paraquat results in increased expression of GPX1 mRNA
Paraquat affects the expression of GPX1 protein
Paraquat results in decreased expression of GPX1 mRNA
[Maneb co-treated with Paraquat] results in increased expression of GPX1 mRNA; [Paraquat results in increased abundance of Reactive Oxygen Species] which results in decreased expression of GPX1 mRNA; Estradiol affects the reaction [Paraquat affects the expression of GPX1 protein]
GPX1 protein results in decreased susceptibility to Paraquat
GPX1 protein affects the reaction [Paraquat affects the expression of BAX mRNA]; GPX1 protein affects the reaction [Paraquat affects the expression of BCL2 mRNA]; GPX1 protein affects the reaction [Paraquat affects the expression of BCL2L2 mRNA]; GPX1 protein affects the reaction [Paraquat affects the expression of GADD45A mRNA]; GPX1 protein affects the reaction [Paraquat affects the expression of MDM2 mRNA]; GPX1 protein affects the reaction [Paraquat affects the expression of MYC mRNA]; GPX1 protein affects the reaction [Paraquat results in increased activity of CASP3 protein]; GPX1 protein affects the reaction [Paraquat results in increased expression of BCL2L1 protein]; GPX1 protein affects the reaction [Paraquat results in increased expression of CASP3 protein]; pirfenidone inhibits the reaction [Paraquat results in decreased expression of GPX1 mRNA]; Sodium Selenite affects the reaction [GPX1 gene mutant form affects the susceptibility to Paraquat]
[Plant Extracts co-treated with Paraquat] results in increased expression of GPX1 mRNA; GPX1 protein results in decreased susceptibility to [Paraquat co-treated with Maneb]; Plant Extracts inhibits the reaction [Paraquat results in decreased expression of GPX1 mRNA]
GPX1 gene mutant form results in increased susceptibility to Paraquat
CTD PMID:11568445, PMID:12595580, PMID:12654481, PMID:15182862, PMID:15824117, PMID:17935786, PMID:18686095, PMID:21371552, PMID:24141985, PMID:24376630, PMID:26108578, PMID:29273418, PMID:29287252, PMID:29859004, PMID:30243747, PMID:31715309 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression
multiple interactions
decreases expression
affects expression
ISO Paraquat results in increased expression of GPX2 mRNA
[Paraquat co-treated with naringenin] results in increased expression of GPX2 mRNA
Paraquat results in decreased expression of GPX2 mRNA
APOD protein affects the reaction [Paraquat results in decreased expression of GPX2 mRNA]
Paraquat affects the expression of GPX2 mRNA
CTD PMID:10806356, PMID:12732627, PMID:21688324, PMID:24561720 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245
JBrowse link
G Gpx3 glutathione peroxidase 3 affects expression
multiple interactions
decreases expression
increases expression
EXP
ISO
Paraquat affects the expression of GPX3 mRNA
[Paraquat co-treated with naringenin] results in increased expression of GPX3 mRNA; [Paraquat co-treated with Thioctic Acid] results in increased expression of GPX3 mRNA
Paraquat results in decreased expression of GPX3 mRNA
Paraquat results in increased expression of GPX3 mRNA
APOD protein affects the reaction [Paraquat results in increased expression of GPX3 mRNA]
CTD PMID:12732627, PMID:15206577, PMID:18198484, PMID:21688324, PMID:23649336, PMID:24561720 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422
JBrowse link
G Gpx4 glutathione peroxidase 4 increases response to substance
multiple interactions
increases expression
decreases response to substance
ISO GPX4 gene mutant form results in increased susceptibility to Paraquat
[Paraquat co-treated with Maneb] results in decreased expression of GPX4 protein
[Paraquat co-treated with Maneb] results in decreased expression of GPX4 protein; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of GPX4 protein]
Paraquat results in increased expression of GPX4 mRNA
GPX4 protein results in decreased susceptibility to Paraquat
CTD PMID:12566075, PMID:12732627, PMID:30797899 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Gpx5 glutathione peroxidase 5 increases expression
multiple interactions
ISO Paraquat results in increased expression of GPX5 mRNA
[Paraquat co-treated with naringenin] results in increased expression of GPX5 mRNA; [Quercetin co-treated with Paraquat] results in increased expression of GPX5 mRNA
CTD PMID:22996356, PMID:24561720 NCBI chr17:45,508,657...45,518,686
Ensembl chr17:45,467,015...45,518,686
JBrowse link
G Gpx7 glutathione peroxidase 7 multiple interactions ISO [Paraquat co-treated with naringenin] results in increased expression of GPX7 mRNA CTD PMID:24561720 NCBI chr 5:128,001,766...128,009,610
Ensembl chr 5:128,001,761...128,009,735
JBrowse link
G Grb2 growth factor receptor bound protein 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of GRB2 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of GRB2 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of GRB2 mRNA] CTD PMID:23963992 NCBI chr10:104,193,953...104,263,071
Ensembl chr10:104,193,955...104,263,071
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 decreases expression EXP Paraquat results in decreased expression of GRIA2 protein CTD PMID:24521700 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629
JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 decreases expression EXP Paraquat results in decreased expression of GRIK3 mRNA CTD PMID:18198484 NCBI chr 5:143,500,441...143,715,546
Ensembl chr 5:143,500,441...143,715,546
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 decreases expression
multiple interactions
EXP Paraquat results in decreased expression of GRIN1 mRNA; Paraquat results in decreased expression of NMDAR1 protein
Estradiol inhibits the reaction [Paraquat results in decreased expression of NMDAR1 protein]
CTD PMID:19146868, PMID:28916328, PMID:31715309 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663
JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A increases expression ISO
EXP
Paraquat results in increased expression of GRIN2A mRNA CTD PMID:18198484, PMID:22563483 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990
JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B increases expression
affects expression
ISO
EXP
Paraquat results in increased expression of GRIN2B mRNA
Paraquat affects the expression of GRIN2B mRNA
CTD PMID:15206577, PMID:22563483 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873
JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C increases expression EXP Paraquat results in increased expression of GRIN2C mRNA CTD PMID:18198484 NCBI chr10:103,798,290...103,816,923
Ensembl chr10:103,798,291...103,816,287
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 decreases expression EXP Paraquat results in decreased expression of GRK2 protein CTD PMID:24521700 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328
JBrowse link
G Grm2 glutamate metabotropic receptor 2 affects expression EXP Paraquat affects the expression of GRM2 mRNA CTD PMID:15206577 NCBI chr 8:115,344,999...115,358,628
Ensembl chr 8:115,344,999...115,358,046
JBrowse link
G Grm6 glutamate metabotropic receptor 6 increases expression EXP Paraquat results in increased expression of GRM6 mRNA CTD PMID:18198484 NCBI chr10:36,345,503...36,363,416
Ensembl chr10:36,345,939...36,360,665
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha affects expression
increases phosphorylation
decreases expression
multiple interactions
EXP
ISO
Paraquat affects the expression of GSK3A mRNA
Paraquat results in increased phosphorylation of GSK3A protein
Paraquat results in decreased expression of GSK3A protein
6-bromoindirubin-3'-oxime promotes the reaction [Paraquat results in decreased expression of GSK3A protein modified form]
CTD PMID:15206577, PMID:28414160, PMID:30205152 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
decreases phosphorylation
increases phosphorylation
decreases expression
ISO Lithium Chloride inhibits the reaction [Paraquat results in decreased phosphorylation of GSK3B protein]; Paraquat results in increased expression of and results in increased phosphorylation of GSK3B protein
Paraquat results in increased phosphorylation of GSK3B protein
6-bromoindirubin-3'-oxime promotes the reaction [Paraquat inhibits the reaction [TNFRSF10B protein binds to GSK3B protein]]; 6-bromoindirubin-3'-oxime promotes the reaction [Paraquat results in decreased expression of GSK3B protein modified form]; Paraquat inhibits the reaction [TNFRSF10B protein binds to GSK3B protein]; WNT1 protein inhibits the reaction [Paraquat results in decreased phosphorylation of GSK3B protein]
CTD PMID:22292029, PMID:24634145, PMID:28414160, PMID:30171970, PMID:30205152 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsr glutathione-disulfide reductase decreases expression
decreases activity
affects expression
multiple interactions
increases expression
ISO
EXP
Paraquat results in decreased expression of GSR mRNA; Paraquat results in decreased expression of GSR protein
Paraquat results in decreased activity of GSR protein
Paraquat affects the expression of GSR protein
[Plant Extracts co-treated with Paraquat] results in increased expression of GSR mRNA; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Paraquat results in decreased activity of GSR protein]; Paraquat inhibits the reaction [naringenin results in increased expression of GSR mRNA]
[Acetylcysteine co-treated with Paraquat co-treated with Maneb] results in increased activity of GSR protein; [Acetylcysteine co-treated with Paraquat] results in increased activity of GSR protein; [Silymarin co-treated with Paraquat co-treated with Maneb] results in increased activity of GSR protein; [Silymarin co-treated with Paraquat] results in increased activity of GSR protein; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]; Acetylcysteine inhibits the reaction [Paraquat results in decreased activity of GSR protein]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in decreased activity of GSR protein]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]]; EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]; EUK-134 inhibits the reaction [Paraquat results in decreased activity of GSR protein]; EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in decreased activity of GSR protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]]; Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]; Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]
Paraquat results in increased expression of GSR mRNA
Dapsone inhibits the reaction [Paraquat results in decreased expression of GSR protein]; Dapsone inhibits the reaction [Paraquat results in increased expression of GSR mRNA]
CTD PMID:10699569, PMID:12954614, PMID:15754033, PMID:16797015, PMID:17215068, PMID:20553223, PMID:21765237, PMID:23159886, PMID:24141985, PMID:24561720, PMID:25724285, PMID:28467894, PMID:30185695 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP
ISO
Paraquat results in increased expression of GSTA2 mRNA CTD PMID:16128001, PMID:16328009 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta3 glutathione S-transferase alpha 3 decreases expression
increases expression
ISO
EXP
Paraquat results in decreased expression of GSTA3 mRNA
Paraquat results in increased expression of GSTA3 mRNA
CTD PMID:12595580, PMID:16128001, PMID:17215068, PMID:18620719, PMID:20888808 NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023
JBrowse link
G Gsta4 glutathione S-transferase alpha 4 multiple interactions
increases expression
increases activity
EXP [Acetylcysteine co-treated with EUK-134] promotes the reaction [[Zinc Sulfate co-treated with Paraquat] results in increased activity of GSTA4 protein]; [EUK-134 co-treated with Acetylcysteine] promotes the reaction [Paraquat results in increased activity of GSTA4 protein]; [Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of GSTA4 protein; [Paraquat co-treated with Maneb] results in increased expression of GSTA4 mRNA; [Zinc Sulfate co-treated with Paraquat] results in increased activity of GSTA4 protein; Acetylcysteine promotes the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of GSTA4 protein]; Acetylcysteine promotes the reaction [[Paraquat co-treated with Maneb] results in increased expression of GSTA4 mRNA]; Acetylcysteine promotes the reaction [Paraquat results in increased expression of and results in increased activity of GSTA4 protein]; Acetylcysteine promotes the reaction [Paraquat results in increased expression of GSTA4 mRNA]; Paraquat promotes the reaction [Zinc Sulfate results in increased expression of GSTA4 mRNA]; Paraquat results in increased expression of and results in increased activity of GSTA4 protein; Silymarin promotes the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of GSTA4 protein]; Silymarin promotes the reaction [[Paraquat co-treated with Maneb] results in increased expression of GSTA4 mRNA]; Silymarin promotes the reaction [Paraquat results in increased expression of and results in increased activity of GSTA4 protein]; Silymarin promotes the reaction [Paraquat results in increased expression of GSTA4 mRNA]; Zinc Sulfate promotes the reaction [Paraquat results in increased expression of GSTA4 mRNA]
Paraquat results in increased expression of GSTA4 mRNA; Paraquat results in increased expression of GSTA4 protein
CTD PMID:20553223, PMID:20888808, PMID:23159886, PMID:24521700, PMID:25724285 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases expression ISO Paraquat results in increased expression of GSTA1 mRNA CTD PMID:16128001 NCBI chr 8:85,553,659...85,564,914
Ensembl chr 8:85,553,734...85,565,179
JBrowse link
G Gsta6 glutathione S-transferase alpha 6 increases expression ISO Paraquat results in increased expression of GSTA2 mRNA CTD PMID:16128001 NCBI chr 9:27,475,273...27,533,939
Ensembl chr 9:27,475,273...27,511,176
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression
affects expression
ISO Paraquat results in increased expression of GSTM1 mRNA
Paraquat affects the expression of GSTM5 mRNA
CTD PMID:16128001, PMID:27788593 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression
decreases expression
EXP
ISO
Paraquat results in increased expression of GSTM2 mRNA
Paraquat results in decreased expression of GSTM2 mRNA
CTD PMID:16128001, PMID:16555045, PMID:17935786, PMID:21371552 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856
JBrowse link
G Gstm3 glutathione S-transferase mu 3 increases expression ISO Paraquat results in increased expression of GSTM3 mRNA CTD PMID:20883675 NCBI chr 2:210,685,204...210,688,273
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression ISO Paraquat results in increased expression of GSTM3 mRNA CTD PMID:16128001, PMID:20883675 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272
JBrowse link
G Gsto1 glutathione S-transferase omega 1 increases expression ISO Paraquat results in increased expression of GSTO1 mRNA CTD PMID:16128001 NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression
increases expression
multiple interactions
ISO Paraquat results in decreased expression of GSTP1 protein
Paraquat results in increased expression of GSTP1 mRNA
[Maneb co-treated with Paraquat] results in decreased expression of GSTP1 mRNA; Dapsone inhibits the reaction [Paraquat results in decreased expression of GSTP1 protein]; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of GSTP1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of GSTP1 mRNA]
CTD PMID:16128001, PMID:18620719, PMID:21765237, PMID:23963992 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects response to substance ISO GSTT1 protein affects the susceptibility to Paraquat CTD PMID:23045187 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Gstt2 glutathione S-transferase, theta 2 increases expression EXP Paraquat results in increased expression of GSTT2 protein CTD PMID:24521700 NCBI chr20:13,760,810...13,764,481
Ensembl chr20:13,760,810...13,764,475
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 increases expression
multiple interactions
ISO Paraquat results in increased expression of GSTZ1 mRNA
[Paraquat co-treated with Quercetin] results in increased expression of GSTZ1 mRNA; Paraquat inhibits the reaction [naringenin results in increased expression of GSTZ1 mRNA]
CTD PMID:22996356, PMID:24561720 NCBI chr 6:111,176,798...111,187,246
Ensembl chr 6:111,176,798...111,187,244
JBrowse link
G Gtpbp1 GTP binding protein 1 decreases expression ISO Paraquat results in decreased expression of GTPBP1 mRNA CTD PMID:21371552 NCBI chr 7:120,923,274...120,947,723
Ensembl chr 7:120,923,274...120,947,723
JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 increases expression EXP Paraquat results in increased expression of GUCY1A1 mRNA CTD PMID:20388547 NCBI chr 2:181,045,694...181,103,321
Ensembl chr 2:181,045,703...181,102,918
JBrowse link
G Guk1 guanylate kinase 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of GUK1 mRNA CTD PMID:18386188 NCBI chr10:45,535,617...45,552,455
Ensembl chr10:45,535,627...45,543,897
JBrowse link
G H2ac20 H2A clustered histone 20 decreases expression
multiple interactions
ISO Paraquat results in decreased expression of H2AC20 mRNA
[Paraquat co-treated with Maneb] affects the expression of H2AC20 mRNA
CTD PMID:22563483 NCBI chr 2:198,360,271...198,360,735
Ensembl chr 2:198,360,301...198,360,678
JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases expression
ISO ATG7 protein affects the reaction [Paraquat results in increased expression of H2AX protein] CTD PMID:28012437 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G H2bc9 H2B clustered histone 9 multiple interactions
decreases expression
ISO [Paraquat co-treated with Maneb] affects the expression of H2BC9 mRNA
Paraquat results in decreased expression of H2BC9 mRNA
CTD PMID:22563483 NCBI chr17:44,519,815...44,520,269
Ensembl chr17:44,519,860...44,520,240
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions ISO [ABCB1A gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of HAVCR1 mRNA; [ABCB1B gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of HAVCR1 mRNA; [SLC47A1 gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of HAVCR1 mRNA CTD PMID:21991918, PMID:25015657 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Hba-a1 hemoglobin alpha, adult chain 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of HBA-A1 mRNA CTD PMID:18386188 NCBI chr10:15,602,794...15,603,649
Ensembl chr10:15,602,794...15,603,649
JBrowse link
G Hbb hemoglobin subunit beta decreases expression ISO Paraquat results in decreased expression of HBB-B1 mRNA CTD PMID:21371552 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hdac4 histone deacetylase 4 decreases expression EXP Paraquat results in decreased expression of HDAC4 protein CTD PMID:21777615 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715
JBrowse link
G Hdac7 histone deacetylase 7 decreases expression EXP Paraquat results in decreased expression of HDAC7 protein CTD PMID:21777615 NCBI chr 7:139,280,396...139,319,108
Ensembl chr 7:139,281,187...139,318,455
JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Paraquat results in increased expression of HERPUD1 mRNA CTD PMID:12595580 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254
JBrowse link
G Hes3 hes family bHLH transcription factor 3 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of HES3 mRNA CTD PMID:22563483 NCBI chr 5:169,463,196...169,469,795
Ensembl chr 5:169,464,989...169,467,153
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of HEY2 mRNA CTD PMID:23017109 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531
JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of HEYL mRNA CTD PMID:23017109 NCBI chr 5:140,923,914...140,940,905
Ensembl chr 5:140,923,914...140,940,905
JBrowse link
G Hfe homeostatic iron regulator affects response to substance
multiple interactions
ISO HFE protein alternative form affects the susceptibility to Paraquat
[HFE protein alternative form affects the susceptibility to Paraquat] which affects the expression of NFE2L2; HFE protein alternative form affects the reaction [Paraquat results in decreased expression of TOMM20 protein]; HFE protein alternative form affects the reaction [Paraquat results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [HFE protein alternative form affects the susceptibility to Paraquat]
CTD PMID:32540480 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985
JBrowse link
G Hgf hepatocyte growth factor increases expression ISO Paraquat results in increased expression of HGF mRNA CTD PMID:16324872 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions
ISO
EXP
Paraquat results in increased expression of HIF1A protein
Paraquat results in increased expression of HIF1A mRNA; Paraquat results in increased expression of HIF1A protein
HIF1A protein affects the reaction [Paraquat results in decreased expression of TJP1 protein]; HIF1A protein affects the reaction [Paraquat results in increased expression of ACTA2 protein]
CTD PMID:26781174 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hist1h2af histone cluster 1 H2A family member F decreases expression
multiple interactions
ISO Paraquat results in decreased expression of H2AC6 mRNA
[Paraquat co-treated with Maneb] affects the expression of H2AC6 mRNA
CTD PMID:22563483 NCBI chr17:43,627,237...43,627,629
Ensembl chr17:43,627,237...43,627,629
JBrowse link
G Hk1 hexokinase 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of HK1 mRNA CTD PMID:18386188 NCBI chr20:31,911,460...31,979,780
Ensembl chr20:31,912,262...31,956,649
JBrowse link
G Hm13 histocompatibility minor 13 decreases expression ISO Paraquat results in decreased expression of H13 mRNA CTD PMID:21371552 NCBI chr 3:148,150,695...148,189,623
Ensembl chr 3:148,150,698...148,189,623
JBrowse link
G Hmga2 high mobility group AT-hook 2 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of HMGA2 mRNA CTD PMID:18386188 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408
JBrowse link
G Hmgb1 high mobility group box 1 increases expression EXP Paraquat results in increased expression of HMGB1 mRNA CTD PMID:19497220 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase decreases expression EXP
ISO
Paraquat results in decreased expression of HMGCL mRNA CTD PMID:17077588, PMID:21371552 NCBI chr 5:154,294,841...154,308,582
Ensembl chr 5:154,294,806...154,308,640
JBrowse link
G Hmgn5 high mobility group nucleosome binding domain 5 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of HMGN5 mRNA CTD PMID:22563483 NCBI chr  X:80,134,557...80,142,902
Ensembl chr  X:80,134,557...80,142,902
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
affects expression
affects activity
increases activity
decreases expression
increases expression
EXP
ISO
[Mifepristone co-treated with Paraquat] results in increased expression of HMOX1 mRNA; [Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased expression of HMOX1 mRNA; alpha-Tocopherol inhibits the reaction [Paraquat results in increased activity of HMOX1 protein]; Curcumin inhibits the reaction [Paraquat results in increased activity of HMOX1 protein]; Estradiol affects the reaction [Paraquat affects the expression of HMOX1 protein]; Hemin promotes the reaction [Paraquat results in increased expression of HMOX1 mRNA]; NFE2L2 protein promotes the reaction [[Mifepristone co-treated with Paraquat] results in increased expression of HMOX1 mRNA]; Quercetin inhibits the reaction [Paraquat results in increased expression of HMOX1]; SB 203580 promotes the reaction [[Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased expression of HMOX1 mRNA]
Paraquat affects the expression of HMOX1 mRNA
Paraquat affects the activity of HMOX1 protein
Paraquat results in decreased expression of HMOX1 mRNA; Paraquat results in decreased expression of HMOX1 protein
Paraquat results in increased expression of HMOX1 mRNA; Paraquat results in increased expression of HMOX1 protein
Paraquat results in increased expression of HMOX1; Paraquat results in increased expression of HMOX1 mRNA; Paraquat results in increased expression of HMOX1 protein
2-tert-butylhydroquinone inhibits the reaction [Paraquat results in increased expression of HMOX1 protein]; naringin inhibits the reaction [Paraquat results in decreased expression of HMOX1 mRNA]; naringin inhibits the reaction [Paraquat results in decreased expression of HMOX1 protein]; Paraquat affects the reaction [APOD protein affects the expression of HMOX1 protein]; plant extract, Puerariae Radix inhibits the reaction [Paraquat results in decreased expression of HMOX1 protein]; resveratrol promotes the reaction [Paraquat results in increased activity of HMOX1 protein]; SIRT1 protein affects the reaction [Paraquat affects the activity of HMOX1 protein]
[Paraquat co-treated with Ellagic Acid] results in increased expression of HMOX1 mRNA; [Paraquat co-treated with Ellagic Acid] results in increased expression of HMOX1 protein; [Paraquat co-treated with naringenin] results in increased expression of HMOX1 mRNA; [Paraquat co-treated with Quercetin] results in increased expression of HMOX1 mRNA; [Paraquat co-treated with Thioctic Acid] results in increased expression of HMOX1 mRNA; [Paraquat co-treated with Thioctic Acid] results in increased expression of HMOX1 protein; [Quercetin co-treated with Paraquat] results in increased expression of HMOX1 protein; [SNCA protein co-treated with Paraquat co-treated with Dopamine] results in increased expression of HMOX1 protein; Resveratrol promotes the reaction [Paraquat results in increased expression of HMOX1 mRNA]; Silymarin promotes the reaction [Paraquat results in increased expression of HMOX1 mRNA]; Silymarin promotes the reaction [Paraquat results in increased expression of HMOX1 protein]
Paraquat affects the expression of HMOX1 mRNA; Paraquat affects the expression of HMOX1 protein
CTD PMID:11181820, PMID:12180188, PMID:15527874, PMID:15728566, PMID:16263688, PMID:16328009, PMID:16555045, PMID:16854511, PMID:17215068, PMID:17409708, PMID:17935786, PMID:18620719, PMID:19080378, PMID:20095327, PMID:20600150, PMID:21688324, PMID:21735318, PMID:22493042, PMID:22709784, PMID:22983789, PMID:22996356, PMID:23546295, PMID:23603004, PMID:23649336, PMID:24376630, PMID:24521700, PMID:24561720, PMID:24812154, PMID:25169090, PMID:26598004, PMID:26649146, PMID:26708779, PMID:26758514, PMID:26935021, PMID:27788593, PMID:28467894, PMID:31715309 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hmox2 heme oxygenase 2 increases expression EXP Paraquat results in increased expression of HMOX2 mRNA CTD PMID:17935786 NCBI chr10:10,990,034...11,035,493
Ensembl chr10:10,990,034...11,035,484
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 increases expression
decreases expression
ISO Paraquat results in increased expression of HNRNPA2B1 mRNA alternative form
Paraquat results in decreased expression of HNRNPA2B1 protein
CTD PMID:17064354, PMID:27111068 NCBI chr 4:81,237,496...81,241,281
Ensembl chr 4:81,237,496...81,241,282
JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C multiple interactions ISO [HNRNPC protein binds to HNRNPC protein alternative form] which results in decreased susceptibility to Paraquat CTD PMID:16960656 NCBI chr15:28,486,605...28,517,353
Ensembl chr15:28,486,617...28,517,353
JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D increases expression ISO Paraquat results in increased expression of HNRNPD mRNA alternative form CTD PMID:17064354 NCBI chr14:11,256,163...11,274,684
Ensembl chr14:11,256,268...11,274,578
JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 decreases expression ISO Paraquat results in decreased expression of HNRNPH1 mRNA; Paraquat results in decreased expression of HNRNPH1 protein CTD PMID:27111068 NCBI chr10:35,872,619...35,879,911
Ensembl chr10:35,870,232...35,879,910
JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K multiple interactions
increases expression
ISO
EXP
[Paraquat co-treated with Maneb] results in decreased expression of HNRNPK mRNA
Paraquat results in increased expression of HNRNPK mRNA
CTD PMID:16328009, PMID:18386188 NCBI chr17:6,664,730...6,676,753
Ensembl chr17:6,665,659...6,676,654
JBrowse link
G Homer2 homer scaffold protein 2 decreases expression ISO Paraquat results in decreased expression of HOMER2 mRNA CTD PMID:21371552 NCBI chr 1:143,443,300...143,535,579
Ensembl chr 1:143,443,300...143,535,583
JBrowse link
G Hoxa3 homeobox A3 decreases expression ISO Paraquat results in decreased expression of HOXA3 mRNA CTD PMID:26824344 NCBI chr 4:82,137,802...82,181,836
Ensembl chr 4:82,138,683...82,141,385
JBrowse link
G Hoxb13 homeo box B13 increases response to substance ISO HOXB13 protein results in increased susceptibility to Paraquat CTD PMID:24213000 NCBI chr10:84,031,955...84,034,228
Ensembl chr10:84,031,955...84,034,228
JBrowse link
G Hpcal1 hippocalcin-like 1 increases expression ISO Paraquat results in increased expression of HPCAL1 mRNA CTD PMID:12595580 NCBI chr 6:43,001,920...43,109,083
Ensembl chr 6:43,001,948...43,109,071
JBrowse link
G Hpn hepsin decreases expression ISO Paraquat results in decreased expression of HPN mRNA CTD PMID:16797015 NCBI chr 1:89,534,112...89,549,575
Ensembl chr 1:89,534,106...89,543,967
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression ISO Paraquat results in increased expression of HPRT1 mRNA CTD PMID:21371552 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Hras HRas proto-oncogene, GTPase affects splicing ISO Paraquat affects the splicing of HRAS mRNA CTD PMID:23613995 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hrk harakiri, BCL2 interacting protein decreases expression ISO Paraquat results in decreased expression of HRK mRNA CTD PMID:18836921 NCBI chr12:44,008,879...44,029,211 JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases expression EXP Paraquat results in increased expression of HSD11B1 mRNA CTD PMID:18198484 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 decreases expression
increases expression
ISO Paraquat results in decreased expression of HSD17B12 mRNA
Paraquat results in increased expression of HSD17B12 mRNA
CTD PMID:21371552 NCBI chr 3:82,924,699...83,048,465
Ensembl chr 3:82,924,687...83,048,435
JBrowse link
G Hsf1 heat shock transcription factor 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of HSF1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of HSF1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of HSF1 mRNA] CTD PMID:23963992 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of HSP90AA1 mRNA; [Paraquat co-treated with Maneb] results in increased expression of HSP90AA1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of HSP90AA1 mRNA] CTD PMID:18386188, PMID:23963992 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 increases expression EXP Paraquat results in increased expression of HSP90B1 mRNA CTD PMID:17935786 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression ISO Paraquat results in decreased expression of HSPA1A mRNA CTD PMID:20883675 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of HSPA1B mRNA; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of HSPA1B mRNA] CTD PMID:23963992 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like decreases response to substance ISO HSPA1L protein results in decreased susceptibility to Paraquat CTD PMID:24887138 NCBI chr20:4,879,998...4,965,191
Ensembl chr20:4,959,294...4,964,963
JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 decreases expression ISO Paraquat results in decreased expression of HSPA2 mRNA CTD PMID:20883675 NCBI chr 6:99,433,575...99,436,288
Ensembl chr 6:99,433,550...99,436,289
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions
ISO
EXP
Paraquat results in increased expression of HSPA5 mRNA; Paraquat results in increased expression of HSPA5 protein
[Paraquat co-treated with Maneb] results in increased expression of HSPA5 mRNA
Minocycline inhibits the reaction [Paraquat results in increased expression of HSPA5 protein]; NFE2L2 mutant form inhibits the reaction [Paraquat results in increased expression of HSPA5 mRNA]; NFE2L2 mutant form inhibits the reaction [Paraquat results in increased expression of HSPA5 protein]
EIF2S1 protein promotes the reaction [salubrinal inhibits the reaction [Paraquat results in increased expression of HSPA5 protein]]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Paraquat results in increased expression of HSPA5 protein]; salubrinal inhibits the reaction [Paraquat results in increased expression of HSPA5 protein]
CTD PMID:17935786, PMID:18198484, PMID:18386188, PMID:19735704, PMID:20883675, PMID:22245251, PMID:22678742, PMID:24912635, PMID:27442881, PMID:28986289, PMID:30185695 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of HSPA8 mRNA CTD PMID:18386188 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 increases expression EXP Paraquat results in increased expression of HSPA9 mRNA CTD PMID:17935786 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 affects expression
decreases expression
EXP
ISO
Paraquat affects the expression of HSPB1 mRNA
Paraquat results in decreased expression of HSPB1 mRNA
CTD PMID:15206577, PMID:20883675, PMID:21371552 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression
multiple interactions
decreases expression
EXP
ISO
Paraquat results in increased expression of HSPD1 protein
HSPD1 protein promotes the reaction [Paraquat results in increased expression of IL1B mRNA]; HSPD1 protein promotes the reaction [Paraquat results in increased expression of IL6 mRNA]; HSPD1 protein promotes the reaction [Paraquat results in increased expression of MYD88 protein]; HSPD1 protein promotes the reaction [Paraquat results in increased expression of NOS2 mRNA]; HSPD1 protein promotes the reaction [Paraquat results in increased expression of TLR4 protein]; HSPD1 protein promotes the reaction [Paraquat results in increased expression of TNF mRNA]
Paraquat results in decreased expression of HSPD1 protein
Paraquat results in increased expression of HSPD1 mRNA
CTD PMID:11746186, PMID:20883675, PMID:27788593, PMID:30584891 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression EXP
ISO
Paraquat results in increased expression of HSPE1 mRNA CTD PMID:17935786, PMID:20883675 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599
JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B decreases expression EXP Paraquat results in decreased expression of HTR1B mRNA CTD PMID:18198484 NCBI chr 8:89,113,984...89,130,830
Ensembl chr 8:89,129,453...89,130,991
JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A decreases expression
multiple interactions
affects localization
EXP Paraquat results in decreased expression of HTR2A mRNA
Cyclosporine inhibits the reaction [Paraquat affects the localization of HTR2A protein]; Dibucaine inhibits the reaction [Paraquat affects the localization of HTR2A protein]; diphenyleneiodonium inhibits the reaction [Paraquat affects the localization of HTR2A protein]
CTD PMID:17077588, PMID:25947082 NCBI chr15:56,666,152...56,732,469
Ensembl chr15:56,666,012...56,735,382
JBrowse link
G Htra2 HtrA serine peptidase 2 affects localization
increases transport
multiple interactions
EXP
ISO
Paraquat affects the localization of HTRA2 protein
Paraquat results in increased transport of HTRA2 protein
LGK974 inhibits the reaction [Paraquat results in increased transport of HTRA2 protein]
CTD PMID:22245251, PMID:30205152 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994
JBrowse link
G Htt huntingtin affects response to substance ISO HTT protein affects the susceptibility to Paraquat CTD PMID:24634145 NCBI chr14:81,105,139...81,254,637
Ensembl chr14:81,105,139...81,254,637
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
increases expression
ISO [[Paraquat co-treated with Ditiocarb] results in decreased activity of SOD1 protein] which results in increased expression of ICAM1 protein; [Paraquat results in increased activity of SOD1 protein] which results in decreased expression of ICAM1 protein; [Paraquat results in increased activity of SOD2 protein] which results in decreased expression of ICAM1 protein
[Paraquat co-treated with Maneb] results in increased expression of ICAM1 mRNA; Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of ICAM1 mRNA]
Paraquat results in increased expression of ICAM1 protein
CTD PMID:10644010, PMID:32169474 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Icam2 intercellular adhesion molecule 2 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of ICAM2 mRNA; Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of ICAM2 mRNA] CTD PMID:32169474 NCBI chr10:94,569,889...94,581,218
Ensembl chr10:94,569,890...94,576,512
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein affects expression EXP Paraquat affects the expression of ID1 mRNA CTD PMID:16854511 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 multiple interactions
affects expression
decreases expression
ISO APOD protein affects the reaction [Paraquat results in decreased expression of IDH1 mRNA]
Paraquat affects the expression of IDH1 mRNA
CTD PMID:21688324, PMID:27788593 NCBI chr 9:71,882,108...71,911,645
Ensembl chr 9:71,882,105...71,900,044
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of IDH3A protein; Levodopa inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of IDH3A protein]; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of IDH3A protein] CTD PMID:23562983 NCBI chr 8:59,164,601...59,183,899
Ensembl chr 8:59,164,572...59,183,908
JBrowse link
G Ier5l immediate early response 5-like multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of IER5L mRNA CTD PMID:22563483 NCBI chr 3:9,036,351...9,037,942
Ensembl chr 3:9,036,373...9,037,942
JBrowse link
G Ifna4 interferon, alpha 4 increases expression ISO Paraquat results in increased expression of IFNA4 mRNA CTD PMID:22938100 NCBI chr 5:106,922,563...106,923,132
Ensembl chr 5:106,922,563...106,923,132
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
EXP
ISO
Paraquat results in increased expression of IFNG protein
[Maneb co-treated with Paraquat] results in increased expression of IFNG mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of IFNG mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of IFNG mRNA]
Paraquat results in increased expression of IFNG mRNA; Paraquat results in increased expression of IFNG protein
CTD PMID:12504350, PMID:22938100, PMID:23963992, PMID:26988026 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
increases expression
ISO
EXP
[Maneb co-treated with Paraquat] results in decreased expression of IGF1 mRNA; IGF1 gene mutant form inhibits the reaction [Paraquat results in decreased expression of SLC8A1 protein]; IGF1 gene mutant form inhibits the reaction [Paraquat results in increased expression of ATP2A2 protein]; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of IGF1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of IGF1 mRNA]
Paraquat results in increased expression of IGF1 protein
Paraquat results in increased expression of IGF1 mRNA
CTD PMID:17979500, PMID:20498031, PMID:23898955, PMID:23963992 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf1r insulin-like growth factor 1 receptor affects response to substance
multiple interactions
ISO IGF1R protein affects the susceptibility to Paraquat
Paraquat results in increased expression of and results in increased phosphorylation of IGF1R protein
CTD PMID:23898955 NCBI chr 1:128,924,921...129,213,816
Ensembl chr 1:128,924,966...129,206,516
JBrowse link
G Igf2 insulin-like growth factor 2 increases expression ISO Paraquat results in increased expression of IGF2 mRNA CTD PMID:21371552 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Igf2r insulin-like growth factor 2 receptor increases expression EXP Paraquat results in increased expression of IGF2R mRNA CTD PMID:16328009 NCBI chr 1:48,176,095...48,264,482
Ensembl chr 1:48,176,106...48,264,477
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions EXP Paraquat inhibits the reaction [INS1 protein results in decreased expression of IGFBP1 mRNA] CTD PMID:17213664 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Igfbp5 i