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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:naphthazarin
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Accession:CHEBI:28849 term browser browse the term
Definition:A naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 5 and 8 are replaced by hydroxy groups.
Synonyms:related_synonym: 5,8-Dihydroxy-1,4-naphthoquinone;   5,8-dihydroxy-1,4-naphthalenedione;   5,8-dihydroxy-1,4-naphthosemiquinone;   5,8-dihydroxynaphthoquinone;   Formula=C10H6O4;   InChI=1S/C10H6O4/c11-5-1-2-6(12)10-8(14)4-3-7(13)9(5)10/h1-4,11-12H;   InChIKey=RQNVIKXOOKXAJQ-UHFFFAOYSA-N;   SMILES=Oc1ccc(O)c2C(=O)C=CC(=O)c12;   naphthazarine;   naphthazarone
 alt_id: CHEBI:20521;   CHEBI:7474
 xref: CAS:475-38-7;   KEGG:C01938;   KNApSAcK:C00002846
 xref_mesh: MESH:C005503
 xref: PMID:11667447;   PMID:15644912;   PMID:16019186;   PMID:17432383;   PMID:18309277;   PMID:21667044;   PMID:21765926;   PMID:21904775;   PMID:22513651;   PMID:23537652;   PMID:2435285;   PMID:24587235;   Reaxys:880561;   Wikipedia:5\,8-Dihydroxy-1\,4-naphthoquinone



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naphthazarin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO naphthazarin results in increased expression of CYP1A1 mRNA CTD PMID:26558468 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G Dhodh dihydroorotate dehydrogenase (quinone) decreases activity EXP
ISO
naphthazarin results in decreased activity of DHODH protein CTD PMID:10658902 NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654
JBrowse link

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  CHEBI ontology 19918
    role 19894
      application 19729
        pesticide 17963
          acaricide 13726
            naphthazarin 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic group 18995
                              organic divalent group 18969
                                organodiyl group 18969
                                  carbonyl group 18922
                                    carbonyl compound 18922
                                      ketone 17210
                                        cyclic ketone 15715
                                          quinone 8655
                                            naphthoquinone 1475
                                              1,4-naphthoquinones 1463
                                                hydroxy-1,4-naphthoquinone 157
                                                  naphthazarin 2
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