Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:naphthazarin
go back to main search page
Accession:CHEBI:28849 term browser browse the term
Definition:A naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 5 and 8 are replaced by hydroxy groups.
Synonyms:related_synonym: 5,8-Dihydroxy-1,4-naphthoquinone;   5,8-dihydroxy-1,4-naphthalenedione;   5,8-dihydroxy-1,4-naphthosemiquinone;   5,8-dihydroxynaphthoquinone;   Formula=C10H6O4;   InChI=1S/C10H6O4/c11-5-1-2-6(12)10-8(14)4-3-7(13)9(5)10/h1-4,11-12H;   InChIKey=RQNVIKXOOKXAJQ-UHFFFAOYSA-N;   SMILES=Oc1ccc(O)c2C(=O)C=CC(=O)c12;   naphthazarine;   naphthazarone
 alt_id: CHEBI:20521;   CHEBI:7474
 xref: CAS:475-38-7;   KEGG:C01938;   KNApSAcK:C00002846
 xref_mesh: MESH:C005503
 xref: PMID:11667447;   PMID:15644912;   PMID:16019186;   PMID:17432383;   PMID:18309277;   PMID:21667044;   PMID:21904775;   PMID:22513651;   PMID:23537652;   PMID:2435285;   PMID:24587235;   Reaxys:880561;   Wikipedia:5\,8-Dihydroxy-1\,4-naphthoquinone


show annotations for term's descendants           Sort by:
 
naphthazarin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO naphthazarin results in increased expression of CYP1A1 mRNA CTD PMID:26558468 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Dhodh dihydroorotate dehydrogenase (quinone) decreases activity EXP
ISO
naphthazarin results in decreased activity of DHODH protein CTD PMID:10658902 NCBI chr19:37,551,858...37,573,327
Ensembl chr19:37,558,177...37,591,654
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      application 19471
        pesticide 16973
          acaricide 12039
            naphthazarin 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic group 18728
                              organic divalent group 18719
                                organodiyl group 18719
                                  carbonyl group 18667
                                    carbonyl compound 18667
                                      ketone 16924
                                        cyclic ketone 15393
                                          quinone 8376
                                            naphthoquinone 1436
                                              1,4-naphthoquinones 1422
                                                hydroxy-1,4-naphthoquinone 125
                                                  naphthazarin 2
paths to the root