Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:acarbose
go back to main search page
Accession:CHEBI:2376 term browser browse the term
Definition:A tetrasaccharide derivative consisting of a dideoxy-4-{[4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl C7 cyclitol moiety [called valienol (or valienamine)] linked via nitrogen to isomaltotriose.
Synonyms:exact_synonym: 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranosyl-(1->4)-alpha-D-glucopyranosyl-(1->4)-D-glucopyranose
 related_synonym: Formula=C25H43NO18;   Glucobay;   InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12+,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-/m1/s1;   InChIKey=XUFXOAAUWZOOIT-UGEKTDRHSA-N;   Precose;   SMILES=C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)OC(O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O;   acarbosa;   acarbosum
 alt_id: CHEBI:40513
 xref: CAS:56180-94-0 "ChemIDplus";   CAS:56180-94-0 "KEGG COMPOUND";   DrugBank:DB00284;   Drug_Central:39 "DrugCentral";   HMDB:HMDB0014429;   KEGG:C06802;   KEGG:D00216;   KNApSAcK:C00016021;   LINCS:LSM-4345
 xref_mesh: MESH:D020909
 xref: PMID:11937512 "Europe PMC";   PMID:18248270 "Europe PMC";   PMID:25044702 "Europe PMC";   PMID:8893066 "Europe PMC";   PMID:9805641 "Europe PMC";   Patent:DE2347782;   Patent:US4062950;   Wikipedia:Acarbose
 cyclic_relationship: is_conjugate_base_of CHEBI:84363


show annotations for term's descendants       view all columns           Sort by:
 
acarbose term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464
G Fasn fatty acid synthase JBrowse link 10 109,987,735 110,005,901 RGD:6480464
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:6480464
G Mgam maltase-glucoamylase JBrowse link 4 69,018,592 69,114,027 RGD:6480464
G Npy neuropeptide Y JBrowse link 4 79,557,856 79,565,059 RGD:6480464
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:6480464
G Slc2a1 solute carrier family 2 member 1 JBrowse link 5 138,154,677 138,182,897 RGD:6480464
G Slc2a4 solute carrier family 2 member 4 JBrowse link 10 56,552,921 56,558,562 RGD:6480464
G Sqstm1 sequestosome 1 JBrowse link 10 35,704,728 35,716,316 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19734
    role 19680
      application 19336
        pharmaceutical 19211
          drug 19211
            hypoglycemic agent 3991
              acarbose 12
                acarbose 7(IV)-phosphate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19734
    subatomic particle 19730
      composite particle 19730
        hadron 19730
          baryon 19730
            nucleon 19730
              atomic nucleus 19730
                atom 19730
                  main group element atom 19614
                    p-block element atom 19614
                      carbon group element atom 19506
                        carbon atom 19500
                          organic molecular entity 19500
                            heteroorganic entity 19066
                              organochalcogen compound 18783
                                organooxygen compound 18696
                                  carbohydrates and carbohydrate derivatives 12112
                                    carbohydrate 12112
                                      oligosaccharide 437
                                        tetrasaccharide 12
                                          tetrasaccharide derivative 12
                                            acarbose 12
                                              acarbose 7(IV)-phosphate 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.