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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1] |
CTD |
PMID:10636889 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein] |
CTD |
PMID:15078482 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Actb |
actin, beta |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ACTB mRNA] |
CTD |
PMID:15477007 |
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NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
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G |
Agt |
angiotensinogen |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [AGT protein results in increased expression of VCAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [AGT protein results in increased expression of VCAM1 protein] |
CTD |
PMID:10712386 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased phosphorylation of AKT1 protein] |
CTD |
PMID:24431215 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alb |
albumin |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [ALB protein results in increased abundance of Hydrogen Peroxide]; pyrrolidine dithiocarbamic acid inhibits the reaction [ALB protein results in increased expression of CCL2 mRNA] |
CTD |
PMID:11961005 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Aldh2 |
aldehyde dehydrogenase 2 family member |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of ALDH2 mRNA] |
CTD |
PMID:11578593 |
|
NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
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G |
App |
amyloid beta precursor protein |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid results in decreased susceptibility to [APP protein modified form binds to APP protein modified form] |
CTD |
PMID:17409235 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Ar |
androgen receptor |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of AR mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of AR protein] |
CTD |
PMID:16139439 |
|
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Arhgdia |
Rho GDP dissociation inhibitor alpha |
decreases expression multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid results in decreased expression of ARHGDIA mRNA [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of ARHGDIA mRNA |
CTD |
PMID:15477007 |
|
NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023
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G |
Arpc2 |
actin related protein 2/3 complex, subunit 2 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ARPC2 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471
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G |
Atf4 |
activating transcription factor 4 |
multiple interactions |
ISO EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA] [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA] |
CTD |
PMID:15477007 PMID:20920558 |
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Atp7a |
ATPase copper transporting alpha |
decreases expression |
ISO |
pyrrolidine dithiocarbamic acid results in decreased expression of ATP7A |
CTD |
PMID:25070243 |
|
NCBI chr X:71,094,144...71,201,550
Ensembl chr X:71,094,202...71,198,354
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G |
Bak1 |
BCL2-antagonist/killer 1 |
multiple interactions |
EXP |
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 mRNA; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 protein] |
CTD |
PMID:22085843 |
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NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
EXP |
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX mRNA; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX protein] |
CTD |
PMID:22085843 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
increases phosphorylation multiple interactions |
ISO EXP |
pyrrolidine dithiocarbamic acid results in increased phosphorylation of BCL2 protein [Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 mRNA; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 mRNA]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [resveratrol results in increased expression of BCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of BCL2 mRNA] |
CTD |
PMID:12482581 PMID:16139439 PMID:20920558 PMID:21161674 PMID:22085843 |
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NCBI chr13:22,689,783...22,853,920
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G |
Bcl2a1 |
BCL2-related protein A1 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
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G |
Bcl2l1 |
Bcl2-like 1 |
multiple interactions |
ISO EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of BCL2L1 protein] [Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2L1 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2L1 protein] |
CTD |
PMID:18789402 PMID:22085843 |
|
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Bdnf |
brain-derived neurotrophic factor |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [BDNF protein results in increased expression of SOD2 protein] |
CTD |
PMID:22261313 |
|
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA] |
CTD |
PMID:14527959 |
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NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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G |
Birc5 |
baculoviral IAP repeat-containing 5 |
multiple interactions decreases expression |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [resveratrol results in increased expression of BIRC5 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of BIRC5 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of BIRC5 protein] pyrrolidine dithiocarbamic acid results in decreased expression of BIRC5 protein |
CTD |
PMID:16139439 PMID:21161674 PMID:29541389 |
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NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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G |
Casp1 |
caspase 1 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of CASP1 protein modified form] |
CTD |
PMID:31586597 |
|
NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp3 |
caspase 3 |
multiple interactions |
ISO EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Palmitic Acid results in decreased expression of and results in increased cleavage of CASP3 protein] [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP3 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP3 protein; [pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP3 protein]; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of CASP3 protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein]; MAPK1 protein affects the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP3 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CASP3 protein] [pyrrolidine dithiocarbamic acid binds to Copper] which results in increased activity of CASP3 protein; pyrrolidine dithiocarbamic acid inhibits the reaction [ferruginol results in increased activity of CASP3 protein] |
CTD |
PMID:10941151 PMID:18671963 PMID:20920558 PMID:21687928 PMID:22085843 PMID:28070109 PMID:30086653 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp7 |
caspase 7 |
multiple interactions |
EXP |
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP7 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP7 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein] |
CTD |
PMID:20920558 PMID:22085843 |
|
NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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G |
Casp8 |
caspase 8 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
increases activity multiple interactions |
ISO EXP |
pyrrolidine dithiocarbamic acid results in increased activity of CASP9 protein [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP9 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP9 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein] |
CTD |
PMID:12198114 PMID:20920558 PMID:22085843 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
ISO EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [ALB protein results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA] pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CCL2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA] |
CTD |
PMID:11006087 PMID:11961005 PMID:12016129 PMID:12472797 PMID:16129981 PMID:16600694 PMID:18500357 PMID:22225513 More...
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL20 mRNA] |
CTD |
PMID:11578593 |
|
NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CCL4 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CCL4 protein] |
CTD |
PMID:16129981 |
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NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CCL5 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA] |
CTD |
PMID:10495789 PMID:22225513 |
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NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
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G |
Ccnd1 |
cyclin D1 |
decreases expression multiple interactions |
EXP ISO |
pyrrolidine dithiocarbamic acid results in decreased expression of CCND1 protein pyrrolidine dithiocarbamic acid inhibits the reaction [Shikimic Acid results in increased expression of CCND1 mRNA] |
CTD |
PMID:14603533 PMID:31048002 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Ccne1 |
cyclin E1 |
decreases expression |
EXP |
pyrrolidine dithiocarbamic acid results in decreased expression of CCNE1 protein |
CTD |
PMID:14603533 |
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NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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G |
Ccng1 |
cyclin G1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CCNG1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
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G |
Cct5 |
chaperonin containing TCP1 subunit 5 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930
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G |
Cd14 |
CD14 molecule |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Iron deficiency results in increased expression of CD14 protein] |
CTD |
PMID:20368581 |
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NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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G |
Cd200 |
Cd200 molecule |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648
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G |
Cd44 |
CD44 molecule (Indian blood group) |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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G |
Cdh17 |
cadherin 17 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA]; [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CDH17 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884
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G |
Cdk2 |
cyclin dependent kinase 2 |
decreases expression |
EXP |
pyrrolidine dithiocarbamic acid results in decreased expression of CDK2 protein |
CTD |
PMID:14603533 |
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NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
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G |
Cdk4 |
cyclin-dependent kinase 4 |
decreases expression |
EXP |
pyrrolidine dithiocarbamic acid results in decreased expression of CDK4 protein |
CTD |
PMID:14603533 |
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NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression multiple interactions |
EXP ISO |
pyrrolidine dithiocarbamic acid results in increased expression of CDKN1A protein pyrrolidine dithiocarbamic acid inhibits the reaction [Shikimic Acid results in decreased expression of CDKN1A mRNA] pyrrolidine dithiocarbamic acid inhibits the reaction [Allylamine results in increased expression of CDKN1A protein]; SB 203580 inhibits the reaction [pyrrolidine dithiocarbamic acid results in increased expression of CDKN1A protein] |
CTD |
PMID:14603533 PMID:15048878 PMID:31048002 |
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Allylamine results in increased expression of CDKN1B protein] |
CTD |
PMID:15048878 |
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NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
increases response to substance multiple interactions |
ISO |
CEBPB results in increased susceptibility to pyrrolidine dithiocarbamic acid pyrrolidine dithiocarbamic acid promotes the reaction [CEBPB protein binds to LCMT2 promoter] |
CTD |
PMID:9359698 |
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NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Chuk |
component of inhibitor of nuclear factor kappa B kinase complex |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] |
CTD |
PMID:11739238 |
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NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
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G |
Clec10a |
C-type lectin domain containing 10A |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of CLEC10A mRNA] |
CTD |
PMID:17342418 |
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NCBI chr10:54,876,244...54,880,439
Ensembl chr10:54,876,260...54,880,435
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G |
Cln3 |
CLN3 lysosomal/endosomal transmembrane protein, battenin |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CLN3 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434
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G |
Cnr1 |
cannabinoid receptor 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [gemcitabine results in increased expression of CNR1 mRNA] |
CTD |
PMID:21525939 |
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NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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G |
Cnr2 |
cannabinoid receptor 2 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [gemcitabine results in increased expression of CNR2 mRNA] |
CTD |
PMID:21525939 |
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NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
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G |
Cntnap1 |
contactin associated protein 1 |
increases expression multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid results in increased expression of CNTNAP1 mRNA [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CNTNAP1 mRNA |
CTD |
PMID:15477007 |
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NCBI chr10:86,109,850...86,125,612
Ensembl chr10:86,111,643...86,125,611
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA] |
CTD |
PMID:15078482 |
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Col1a2 |
collagen type I alpha 2 chain |
multiple interactions |
ISO |
atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of COL1A2 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of COL1A2 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of COL1A2 mRNA]] |
CTD |
PMID:34152691 |
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NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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G |
Col6a1 |
collagen type VI alpha 1 chain |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of COL6A1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597
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G |
Comt |
catechol-O-methyltransferase |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of COMT mRNA] |
CTD |
PMID:15477007 |
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NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642
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G |
Cp |
ceruloplasmin |
multiple interactions increases secretion increases expression |
ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in increased expression of CP protein]; Copper promotes the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; Copper promotes the reaction [pyrrolidine dithiocarbamic acid results in increased expression of CP protein] pyrrolidine dithiocarbamic acid results in increased secretion of CP protein pyrrolidine dithiocarbamic acid results in increased expression of CP mRNA; pyrrolidine dithiocarbamic acid results in increased expression of CP protein |
CTD |
PMID:17032174 |
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NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
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G |
Cpsf1 |
cleavage and polyadenylation specific factor 1 |
multiple interactions increases expression |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CPSF1 mRNA pyrrolidine dithiocarbamic acid results in increased expression of CPSF1 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 7:108,319,429...108,330,023
Ensembl chr 7:108,319,434...108,329,934
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CREB1 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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G |
Crem |
cAMP responsive element modulator |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA] |
CTD |
PMID:15477007 |
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NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
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G |
Ctbp1 |
C-terminal binding protein 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CTBP1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr14:77,455,580...77,482,821
Ensembl chr14:77,455,696...77,482,821
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G |
Cul5 |
cullin 5 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 8:54,012,963...54,066,751
Ensembl chr 8:54,016,006...54,066,666
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G |
Cxcl1 |
C-X-C motif chemokine ligand 1 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CXCL1 mRNA] |
CTD |
PMID:16129981 |
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NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
EXP ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CXCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CXCL2 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CXCL2 protein] |
CTD |
PMID:16129981 PMID:21507677 |
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NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
ISO EXP |
[pyrrolidine dithiocarbamic acid binds to Copper] which affects the localization of CYCS protein [Copper co-treated with pyrrolidine dithiocarbamic acid] affects the localization of CYCS protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which affects the localization of CYCS protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] affects the localization of CYCS protein] |
CTD |
PMID:18671963 PMID:20920558 PMID:22085843 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in decreased expression of CYP1A1 mRNA] pyrrolidine dithiocarbamic acid inhibits the reaction [Lead inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lead results in increased expression of CYP1A1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [Copper results in increased expression of CYP1A1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Mercury results in increased expression of CYP1A1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein] |
CTD |
PMID:9756946 PMID:18078826 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp2a1 |
cytochrome P450, family 2, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of CYP2A13 mRNA] |
CTD |
PMID:23884085 |
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NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions |
ISO EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Fenretinide results in increased expression of DDIT3 protein] pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of DDIT3 mRNA] |
CTD |
PMID:16972258 PMID:20920558 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Dnajb1 |
DnaJ heat shock protein family (Hsp40) member B1 |
increases expression multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid results in increased expression of DNAJB1 mRNA [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of DNAJB1 mRNA |
CTD |
PMID:15477007 |
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NCBI chr19:24,522,717...24,526,458
Ensembl chr19:24,522,717...24,526,458
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G |
Dusp4 |
dual specificity phosphatase 4 |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138
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G |
Egf |
epidermal growth factor |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased activity of MMP9 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased expression of MMP9 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased expression of PLAU mRNA] |
CTD |
PMID:16340751 |
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NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions |
ISO |
[Copper binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of EGFR protein |
CTD |
PMID:18346929 |
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NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Egr1 |
early growth response 1 |
multiple interactions increases expression |
ISO |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pyrrolidine dithiocarbamic acid results in increased expression of EGR1 mRNA]; SB 203580 promotes the reaction [pyrrolidine dithiocarbamic acid results in increased expression of EGR1 mRNA] |
CTD |
PMID:12482581 |
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NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
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G |
Egr2 |
early growth response 2 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
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G |
Egr3 |
early growth response 3 |
multiple interactions increases expression |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of EGR3 mRNA pyrrolidine dithiocarbamic acid results in increased expression of EGR3 mRNA |
CTD |
PMID:15477007 |
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NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627
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G |
Erbb4 |
erb-b2 receptor tyrosine kinase 4 |
multiple interactions |
ISO EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [pervanadate results in increased cleavage of ERBB4 protein] |
CTD |
PMID:9685416 |
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NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595
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G |
F3 |
coagulation factor III, tissue factor |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of F3 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of F3 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of F3 protein] |
CTD |
PMID:17141290 |
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NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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G |
Fn1 |
fibronectin 1 |
multiple interactions |
ISO |
atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 mRNA]]; atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of FN1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 protein]] |
CTD |
PMID:12388107 PMID:34152691 |
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NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
ISO EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; Copper promotes the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of FOS mRNA] pyrrolidine dithiocarbamic acid results in increased expression of FOS mRNA pyrrolidine dithiocarbamic acid results in increased expression of FOS protein |
CTD |
PMID:7539260 PMID:15477007 PMID:17032174 |
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Fosl2 |
FOS like 2, AP-1 transcription factor subunit |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOSL2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 6:24,297,898...24,319,157
Ensembl chr 6:24,300,956...24,320,034
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G |
Fyb1 |
FYN binding protein 1 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629
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G |
G3bp2 |
G3BP stress granule assembly factor 2 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of MYH7 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of MYH7 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPB protein] |
CTD |
PMID:28816235 |
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NCBI chr14:15,932,356...16,020,555
Ensembl chr14:15,987,417...16,020,548
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G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
increases expression |
EXP |
pyrrolidine dithiocarbamic acid results in increased expression of GAPDH mRNA |
CTD |
PMID:11108245 |
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NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
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G |
Gata1 |
GATA binding protein 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Aclarubicin results in increased expression of GATA1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Butyric Acid results in increased expression of GATA1 mRNA] |
CTD |
PMID:10656287 |
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NCBI chr X:14,529,706...14,537,530
Ensembl chr X:14,529,702...14,537,530
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G |
Gfra2 |
GDNF family receptor alpha 2 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr15:45,941,841...46,033,715
Ensembl chr15:45,941,828...46,033,714
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G |
Gnas |
GNAS complex locus |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of GNAS mRNA |
CTD |
PMID:15477007 |
|
NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262 Ensembl chr 3:163,071,417...163,127,262
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G |
Gper1 |
G protein-coupled estrogen receptor 1 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone binds to and results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein] |
CTD |
PMID:22645130 |
|
NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
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G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid affects the reaction [GPX1 protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]] |
CTD |
PMID:34082047 |
|
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
increases phosphorylation |
ISO |
pyrrolidine dithiocarbamic acid results in increased phosphorylation of GSK3B protein |
CTD |
PMID:17409235 |
|
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gtf2h2 |
general transcription factor IIH subunit 2 |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of GTF2H2C mRNA |
CTD |
PMID:15477007 |
|
NCBI chr 2:31,623,752...31,652,697
Ensembl chr 2:31,624,678...31,652,592
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G |
Gzma |
granzyme A |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of GZMA mRNA] |
CTD |
PMID:12700414 |
|
NCBI chr 2:44,740,638...44,752,471
Ensembl chr 2:44,740,569...44,752,493
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G |
Gzmb |
granzyme B |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of GZMB mRNA] |
CTD |
PMID:12700414 |
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NCBI chr15:30,343,361...30,346,792
Ensembl chr15:30,173,603...30,346,814
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G |
Hadha |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HADHA mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
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G |
Hars1 |
histidyl-tRNA synthetase 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HARS1 mRNA] |
CTD |
PMID:15477007 |
|
NCBI chr18:28,381,649...28,398,699
Ensembl chr18:28,381,655...28,398,740
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G |
Hck |
HCK proto-oncogene, Src family tyrosine kinase |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HCK mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693
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G |
Hmbs |
hydroxymethylbilane synthase |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Aclarubicin results in increased expression of HMBS mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Butyric Acid results in increased expression of HMBS mRNA] |
CTD |
PMID:10656287 |
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NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957
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G |
Hmgb1 |
high mobility group box 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HMGB1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565
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G |
Hmgcs2 |
3-hydroxy-3-methylglutaryl-CoA synthase 2 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of HMGCS2 mRNA] |
CTD |
PMID:11578593 |
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NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions increases stability increases expression |
ISO EXP |
pyrrolidine dithiocarbamic acid promotes the reaction [Fenretinide results in increased expression of HMOX1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Fenretinide results in increased expression of HMOX1 protein] pyrrolidine dithiocarbamic acid results in increased stability of HMOX1 mRNA pyrrolidine dithiocarbamic acid results in increased expression of HMOX1 mRNA; pyrrolidine dithiocarbamic acid results in increased expression of HMOX1 protein pyrrolidine dithiocarbamic acid promotes the reaction [Copper results in increased expression of HMOX1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Lead results in increased expression of HMOX1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Mercury results in increased expression of HMOX1 mRNA] |
CTD |
PMID:9837857 PMID:16972258 PMID:18078826 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hnrnpul1 |
heterogeneous nuclear ribonucleoprotein U-like 1 |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HNRNPUL1 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 1:81,228,404...81,264,121
Ensembl chr 1:81,228,404...81,262,592
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G |
Hsd11b2 |
hydroxysteroid 11-beta dehydrogenase 2 |
decreases activity |
ISO |
pyrrolidine dithiocarbamic acid results in decreased activity of HSD11B2 protein |
CTD |
PMID:22796344 |
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NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
multiple interactions |
EXP |
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 mRNA] |
CTD |
PMID:20920558 |
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NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions |
EXP |
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 mRNA] |
CTD |
PMID:20920558 |
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Hspa8 |
heat shock protein family A (Hsp70) member 8 |
multiple interactions increases expression |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HSPA8 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA] pyrrolidine dithiocarbamic acid results in increased expression of HSPA8 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
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G |
Hyal3 |
hyaluronidase 3 |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HYAL3 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 8:108,254,385...108,260,020
Ensembl chr 8:108,250,667...108,260,647
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G |
Icam1 |
intercellular adhesion molecule 1 |
multiple interactions decreases expression |
ISO EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of ICAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] pyrrolidine dithiocarbamic acid results in decreased expression of ICAM1 mRNA |
CTD |
PMID:10495789 PMID:12131776 PMID:14572618 PMID:16129981 PMID:17416599 |
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [IFNG protein results in increased abundance of Nitrites] pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid results in decreased susceptibility to [TNF protein co-treated with IFNG protein] |
CTD |
PMID:8903404 PMID:12845421 PMID:18039960 PMID:25766886 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Ifngr2 |
interferon gamma receptor 2 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNGR2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005
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G |
Il10 |
interleukin 10 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Doxorubicin results in increased expression of IL10 mRNA] |
CTD |
PMID:11124598 |
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NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il12b |
interleukin 12B |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] |
CTD |
PMID:15778123 |
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NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
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G |
Il17a |
interleukin 17A |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased activity of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of CXCL8 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of IL6 mRNA] |
CTD |
PMID:12016129 |
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NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
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G |
Il18 |
interleukin 18 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of IL18 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of IL18 mRNA] |
CTD |
PMID:15178407 |
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NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO EXP |
pyrrolidine dithiocarbamic acid affects the reaction [IL1B results in increased expression of CXCL8 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [cobaltous chloride results in increased secretion of IL1B protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ethanol results in increased expression of and results in increased secretion of IL1B protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of FOS mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA] pyrrolidine dithiocarbamic acid inhibits the reaction [[IL1B protein results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased abundance of 8-epi-prostaglandin F2alpha]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of IL1B protein modified form] pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased expression of IL1B protein] |
CTD |
PMID:7539260 PMID:8662662 PMID:11530235 PMID:11578593 PMID:11970852 PMID:12879239 PMID:18039960 PMID:19626664 PMID:21565208 PMID:21779360 PMID:23535185 PMID:25766886 PMID:31586597 PMID:33161052 More...
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il2 |
interleukin 2 |
multiple interactions |
ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA] pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of GZMA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of GZMB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of PRF1 mRNA] |
CTD |
PMID:12700414 PMID:15477007 |
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il2rb |
interleukin 2 receptor subunit beta |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054
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G |
Il6 |
interleukin 6 |
multiple interactions decreases secretion |
EXP ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] pyrrolidine dithiocarbamic acid results in decreased secretion of IL6 protein atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [cobaltous chloride results in increased secretion of IL6 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ethanol results in increased expression of and results in increased secretion of IL6 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of IL6 protein]] |
CTD |
PMID:11970852 PMID:12016129 PMID:21779360 PMID:23535185 PMID:32613688 PMID:33161052 PMID:34152691 More...
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Irf1 |
interferon regulatory factor 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IRF1 protein] |
CTD |
PMID:11739238 |
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NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
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G |
Irf4 |
interferon regulatory factor 4 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IRF4 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression |
ISO |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]]; Copper promotes the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein] pyrrolidine dithiocarbamic acid results in increased expression of JUN mRNA; pyrrolidine dithiocarbamic acid results in increased expression of JUN protein |
CTD |
PMID:12482581 PMID:15477007 PMID:17032174 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Kl |
Klotho |
multiple interactions increases expression |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Indican results in decreased expression of KL mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Indican results in decreased expression of KL protein] pyrrolidine dithiocarbamic acid results in increased expression of KL protein |
CTD |
PMID:21389697 |
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NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
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G |
Klf4 |
Kruppel like factor 4 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of KLF4 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602
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G |
Klf6 |
Kruppel-like factor 6 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of KLF6 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
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G |
Lcmt2 |
leucine carboxyl methyltransferase 2 |
increases expression multiple interactions increases response to substance |
ISO |
pyrrolidine dithiocarbamic acid results in increased expression of LCMT2 mRNA; pyrrolidine dithiocarbamic acid results in increased expression of LCMT2 protein LCMT2 results in increased susceptibility to [pyrrolidine dithiocarbamic acid co-treated with Fluorouracil] LCMT2 results in increased susceptibility to pyrrolidine dithiocarbamic acid pyrrolidine dithiocarbamic acid promotes the reaction [CEBPB protein binds to LCMT2 promoter] |
CTD |
PMID:9359698 |
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NCBI chr 3:108,099,960...108,102,084
Ensembl chr 3:108,099,961...108,102,084
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G |
Lcp1 |
lymphocyte cytosolic protein 1 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of LCP1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680
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G |
Lif |
LIF, interleukin 6 family cytokine |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of LIF mRNA] |
CTD |
PMID:11578593 |
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NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482
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G |
LOC100125598 |
metallothionein 1a pseudogene |
multiple interactions increases expression |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MT1G mRNA pyrrolidine dithiocarbamic acid results in increased expression of MT1G mRNA |
CTD |
PMID:15477007 |
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NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135
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G |
Ltbp4 |
latent transforming growth factor beta binding protein 4 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:82,600,136...82,634,346
Ensembl chr 1:82,600,136...82,632,178
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G |
Madcam1 |
mucosal vascular addressin cell adhesion molecule 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of MADCAM1 protein] |
CTD |
PMID:12388057 |
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NCBI chr 7:10,036,301...10,039,703
Ensembl chr 7:10,036,301...10,039,703
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G |
Map2k2 |
mitogen activated protein kinase kinase 2 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of MAP2K2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
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G |
Map2k4 |
mitogen activated protein kinase kinase 4 |
multiple interactions |
EXP |
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAP2K4 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAP2K4 protein] |
CTD |
PMID:22085843 |
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NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions decreases activity |
ISO EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK1 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein] pyrrolidine dithiocarbamic acid results in decreased activity of MAPK1 protein 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK1 protein]; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK1 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of MAPK1 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of MAPK1 protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of MAPK1 protein]; Glutathione inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of MAPK1 protein]; MAPK1 protein affects the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein]; MAPK1 protein affects the susceptibility to [Copper co-treated with pyrrolidine dithiocarbamic acid] |
CTD |
PMID:10658192 PMID:15477007 PMID:15557793 PMID:20920558 PMID:22085843 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK3 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein] 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK3 protein]; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK3 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of MAPK3 protein; [pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK3 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK3 protein]; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK3 protein] |
CTD |
PMID:10941151 PMID:15477007 PMID:15557793 PMID:20920558 PMID:22085843 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions increases activity |
EXP |
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein; [pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK8 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein]; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK8 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]; pyrazolanthrone inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein] pyrrolidine dithiocarbamic acid results in increased activity of MAPK8 protein |
CTD |
PMID:10658192 PMID:10941151 PMID:20920558 PMID:22085843 |
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NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Mapk9 |
mitogen-activated protein kinase 9 |
multiple interactions |
EXP ISO |
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK9 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK9 protein]; pyrazolanthrone inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK9 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK9 protein] |
CTD |
PMID:15557793 PMID:22085843 |
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NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
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G |
Mapt |
microtubule-associated protein tau |
decreases phosphorylation |
ISO |
pyrrolidine dithiocarbamic acid results in decreased phosphorylation of MAPT protein |
CTD |
PMID:17409235 |
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NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
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G |
Mir146a |
microRNA 146a |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[ferrous sulfate co-treated with aluminum sulfate] results in increased expression of MIR146A mRNA] |
CTD |
PMID:22099153 |
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NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
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G |
Mlxip |
MLX interacting protein |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose affects the localization of MLXIP protein] pyrrolidine dithiocarbamic acid inhibits the reaction [Sucrose affects the localization of MLXIP protein] |
CTD |
PMID:33930463 |
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NCBI chr12:33,128,524...33,192,300
Ensembl chr12:33,128,520...33,192,374
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G |
Mmp1 |
matrix metallopeptidase 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of MMP1 protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased expression of MMP1 mRNA]] |
CTD |
PMID:32613688 |
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NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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G |
Mmp13 |
matrix metallopeptidase 13 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [CPG-oligonucleotide results in increased secretion of MMP13 protein] |
CTD |
PMID:23331101 |
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NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
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G |
Mmp2 |
matrix metallopeptidase 2 |
decreases expression multiple interactions |
ISO EXP |
pyrrolidine dithiocarbamic acid results in decreased expression of MMP2 mRNA pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat affects the expression of MMP2 mRNA] |
CTD |
PMID:19272247 PMID:23566884 |
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp9 |
matrix metallopeptidase 9 |
decreases activity multiple interactions decreases expression |
ISO |
pyrrolidine dithiocarbamic acid results in decreased activity of MMP9 protein pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased activity of MMP9 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased expression of MMP9 mRNA] pyrrolidine dithiocarbamic acid results in decreased expression of MMP9 mRNA |
CTD |
PMID:16340751 PMID:22033475 PMID:23566884 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mpo |
myeloperoxidase |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased activity of MPO protein] |
CTD |
PMID:12879239 |
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NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
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G |
Mst1r |
macrophage stimulating 1 receptor |
decreases expression |
ISO |
pyrrolidine dithiocarbamic acid results in decreased expression of MST1R mRNA |
CTD |
PMID:18593918 |
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NCBI chr 8:108,596,100...108,611,389
Ensembl chr 8:108,597,299...108,612,455
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G |
Mta1 |
metastasis associated 1 |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MTA1 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 6:132,178,608...132,217,641
Ensembl chr 6:132,178,853...132,217,641
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G |
Muc5ac |
mucin 5AC, oligomeric mucus/gel-forming |
multiple interactions |
ISO |
atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of MUC5AC mRNA]]; atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of MUC5AC protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of MUC5AC mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of MUC5AC protein]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of MUC5AC mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased secretion of MUC5AC protein]] |
CTD |
PMID:34152691 |
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NCBI chr 1:196,864,375...196,896,475
Ensembl chr 1:196,864,336...196,896,475
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions decreases expression |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [resveratrol results in increased expression of MYC mRNA] pyrrolidine dithiocarbamic acid results in decreased expression of MYC |
CTD |
PMID:15477007 PMID:21161674 PMID:25070243 |
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Myh1 |
myosin heavy chain 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of MYH1 protein] |
CTD |
PMID:24431215 |
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NCBI chr10:51,885,913...51,909,699
Ensembl chr10:51,885,913...51,946,295
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G |
Myh7 |
myosin heavy chain 7 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of MYH7 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of MYH7 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of MYH7 protein] |
CTD |
PMID:28816235 |
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NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217
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G |
Naa80 |
N(alpha)-acetyltransferase 80, NatH catalytic subunit |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NAA80 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 8:108,254,314...108,257,564
Ensembl chr 8:108,253,302...108,257,563
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G |
Nell1 |
neural EGFL like 1 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NELL1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:99,709,305...100,573,872
Ensembl chr 1:99,709,793...100,573,860
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G |
Nfe2 |
nuclear factor, erythroid 2 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Aclarubicin results in increased expression of NFE2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Butyric Acid results in increased expression of NFE2 mRNA] |
CTD |
PMID:10656287 |
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NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
increases expression multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid results in increased expression of NFE2L2 mRNA [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of NFE2L2 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
ISO EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrogen Peroxide results in increased activity of [RELA protein binds to NFKB1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased activity of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased activity of NFKB1 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NFKB1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased activity of [NFKB1 protein binds to RELA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of NFKB1 protein] |
CTD |
PMID:10416616 PMID:11006087 PMID:11286985 PMID:11578593 PMID:11739238 PMID:11961005 PMID:11970852 PMID:12016129 PMID:14527959 PMID:15178407 More...
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NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkb2 |
nuclear factor kappa B subunit 2 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of NFKB2 mRNA] |
CTD |
PMID:25559736 |
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NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions decreases expression |
ISO EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFKBIA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein] pyrrolidine dithiocarbamic acid results in decreased expression of NFKBIA mRNA pyrrolidine dithiocarbamic acid inhibits the reaction [Ammonium Chloride results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Cadmium Chloride results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein] pyrrolidine dithiocarbamic acid inhibits the reaction [Platelet Activating Factor results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased expression of NFKBIA protein] |
CTD |
PMID:9434740 PMID:10636889 PMID:10921504 PMID:11006087 PMID:11739238 PMID:11923223 PMID:12879239 PMID:17342418 More...
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Ngf |
nerve growth factor |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF protein] |
CTD |
PMID:17651887 |
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NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
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G |
Ngfr |
nerve growth factor receptor |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR protein] |
CTD |
PMID:17651887 |
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NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518
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G |
Nkg7 |
natural killer cell granule protein 7 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NKG7 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:93,844,748...93,845,975
Ensembl chr 1:93,844,902...93,845,983
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G |
Nmi |
N-myc (and STAT) interactor |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NMI mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 3:36,415,607...36,439,716
Ensembl chr 3:36,415,607...36,439,498
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions decreases expression |
ISO EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA] pyrrolidine dithiocarbamic acid results in decreased expression of NOS2 mRNA pyrrolidine dithiocarbamic acid inhibits the reaction [[Ozone results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ammonium Chloride results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Gentamicins results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ozone results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Pyruvaldehyde results in increased expression of NOS2 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Humic Substances results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [Resveratrol results in decreased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Resveratrol results in decreased expression of NOS2 protein] |
CTD |
PMID:7539260 PMID:8662662 PMID:8903404 PMID:9788894 PMID:11530235 PMID:11923223 PMID:12879239 PMID:16925772 PMID:17342418 PMID:17416599 PMID:18039960 PMID:20621070 PMID:21565208 PMID:22227475 PMID:23542513 PMID:23735732 PMID:24239652 PMID:24365262 PMID:24859013 PMID:25766886 PMID:29248572 More...
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Notch3 |
notch receptor 3 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NOTCH3 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025
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G |
Nppa |
natriuretic peptide A |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPA protein] |
CTD |
PMID:28816235 |
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NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
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G |
Nppb |
natriuretic peptide B |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPB protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPB protein] |
CTD |
PMID:28816235 |
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NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
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G |
Nr4a3 |
nuclear receptor subfamily 4, group A, member 3 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
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G |
Odc1 |
ornithine decarboxylase 1 |
multiple interactions increases expression |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of ODC1 mRNA pyrrolidine dithiocarbamic acid results in increased expression of ODC1 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
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G |
Pax8 |
paired box 8 |
multiple interactions decreases expression decreases chemical synthesis |
EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased expression of PAX8 mRNA]; PAX8 protein inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of TPO promoter] pyrrolidine dithiocarbamic acid results in decreased chemical synthesis of PAX8 protein |
CTD |
PMID:11108245 |
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NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
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G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Shikimic Acid results in increased expression of PCNA mRNA] |
CTD |
PMID:31048002 |
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NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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G |
Pla2g1b |
phospholipase A2 group IB |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [PLA2G1B protein results in increased expression of CXCL8 protein] |
CTD |
PMID:15528384 |
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NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226
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G |
Plau |
plasminogen activator, urokinase |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased expression of PLAU mRNA] |
CTD |
PMID:16340751 |
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NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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G |
Pnpla4 |
patatin like phospholipase domain containing 4 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of PNPLA4 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr X:42,313,554...42,318,451
Ensembl chr X:42,305,373...42,318,552
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G |
Pou2f2 |
POU class 2 homeobox 2 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of POU2F2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:80,682,330...80,769,756
Ensembl chr 1:80,685,741...80,724,261
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G |
Ppp1ca |
protein phosphatase 1 catalytic subunit alpha |
decreases expression |
ISO |
pyrrolidine dithiocarbamic acid results in decreased expression of PPP1CA mRNA |
CTD |
PMID:15477007 |
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NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327
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G |
Ppp1r10 |
protein phosphatase 1, regulatory subunit 10 |
increases expression multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid results in increased expression of PPP1R10 mRNA [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of PPP1R10 mRNA |
CTD |
PMID:15477007 |
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NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611
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G |
Prf1 |
perforin 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of PRF1 mRNA] |
CTD |
PMID:12700414 |
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NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [cobaltous chloride results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Homocysteine results in increased expression of PTGS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [sodium arsenite results in increased expression of PTGS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [[IL1B protein results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] pyrrolidine dithiocarbamic acid inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Humic Substances results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of PTGS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] |
CTD |
PMID:8662662 PMID:11530235 PMID:11835400 PMID:16765938 PMID:17767925 PMID:21565208 PMID:21779360 PMID:24239652 PMID:24365262 PMID:24859013 PMID:25888188 PMID:29248572 More...
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NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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G |
Rac1 |
Rac family small GTPase 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [RAC1 protein inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [RAC1 protein results in decreased expression of SERPINE1 mRNA] |
CTD |
PMID:12719791 |
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NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
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G |
Rel |
REL proto-oncogene, NF-kB subunit |
multiple interactions |
ISO EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA] pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides affects the localization of REL protein] |
CTD |
PMID:11970852 PMID:15477007 |
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NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions decreases activity |
ISO EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [ferruginol results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrogen Peroxide results in increased activity of [RELA protein binds to NFKB1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Resveratrol affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]]; Resveratrol promotes the reaction [pyrrolidine dithiocarbamic acid results in decreased expression of RELA] pyrrolidine dithiocarbamic acid inhibits the reaction [Gentamicins results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Pyruvaldehyde affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Pyruvaldehyde results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased phosphorylation of and affects the localization of RELA protein] pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of RELA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased activity of [NFKB1 protein binds to RELA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Sucrose affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of RELA protein] pyrrolidine dithiocarbamic acid results in decreased activity of RELA protein |
CTD |
PMID:10416616 PMID:11739238 PMID:11961005 PMID:11970852 PMID:12016129 PMID:12388107 PMID:14527959 PMID:15178407 PMID:15382119 PMID:16925772 PMID:17767925 PMID:18039960 PMID:20621070 PMID:21161674 PMID:24431215 PMID:24436987 PMID:25559736 PMID:30086653 PMID:31586597 PMID:32613688 PMID:33930463 More...
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Relb |
RELB proto-oncogene, NF-kB subunit |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides affects the localization of RELB protein] |
CTD |
PMID:11970852 |
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NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
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G |
Rhog |
ras homolog family member G |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of RHOG mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:156,618,713...156,630,710
Ensembl chr 1:156,615,349...156,631,257
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G |
Rnaset2 |
ribonuclease T2 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of RNASET2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:52,576,344...52,603,151
Ensembl chr 1:52,585,929...52,603,147
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G |
Sart1 |
spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SART1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:202,690,472...202,699,136
Ensembl chr 1:202,690,459...202,699,136
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G |
Serpine1 |
serpin family E member 1 |
multiple interactions increases expression |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [RAC1 protein inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [RAC1 protein results in decreased expression of SERPINE1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA] pyrrolidine dithiocarbamic acid results in increased expression of SERPINE1 mRNA |
CTD |
PMID:12719791 |
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NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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G |
Sf3b4 |
splicing factor 3B subunit 4 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SF3B4 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 2:183,732,791...183,737,545
Ensembl chr 2:183,732,754...183,737,959
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G |
Sftpc |
surfactant protein C |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of SFTPC protein] |
CTD |
PMID:28070109 |
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NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777
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G |
Sla |
src-like adaptor |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 7:98,534,431...98,584,810
Ensembl chr 7:98,535,368...98,584,648
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G |
Slc1a2 |
solute carrier family 1 member 2 |
increases expression multiple interactions |
ISO EXP |
pyrrolidine dithiocarbamic acid results in increased expression of SLC1A2 protein pyrrolidine dithiocarbamic acid inhibits the reaction [[1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone binds to and results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A2 protein] |
CTD |
PMID:17409235 PMID:22645130 PMID:24782323 |
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NCBI chr 3:89,005,129...89,126,498
Ensembl chr 3:89,005,129...89,126,498
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G |
Slc1a3 |
solute carrier family 1 member 3 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A3 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A3 protein] |
CTD |
PMID:24782323 |
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NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605
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G |
Slc3a2 |
solute carrier family 3 member 2 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLC3A2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
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G |
Snrnp70 |
small nuclear ribonucleoprotein U1 subunit 70 |
multiple interactions increases expression |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of SNRNP70 mRNA pyrrolidine dithiocarbamic acid results in increased expression of SNRNP70 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 1:95,856,039...95,876,434
Ensembl chr 1:95,856,036...95,876,392
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions decreases expression |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of SOD1 mRNA pyrrolidine dithiocarbamic acid results in decreased expression of SOD1 mRNA |
CTD |
PMID:15477007 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
multiple interactions increases expression |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [BDNF protein results in increased expression of SOD2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of SOD2 mRNA] pyrrolidine dithiocarbamic acid results in increased expression of SOD2 mRNA |
CTD |
PMID:9434740 PMID:10653605 PMID:12031898 PMID:22261313 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Spp1 |
secreted phosphoprotein 1 |
decreases expression |
EXP |
pyrrolidine dithiocarbamic acid results in decreased expression of SPP1 |
CTD |
PMID:21076490 |
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NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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G |
Srgn |
serglycin |
multiple interactions increases expression |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of SRGN mRNA pyrrolidine dithiocarbamic acid results in increased expression of SRGN mRNA |
CTD |
PMID:15477007 |
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NCBI chr20:30,442,810...30,479,549
Ensembl chr20:30,442,813...30,457,406
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G |
Sri |
sorcin |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Sucrose results in decreased expression of SRI protein] |
CTD |
PMID:33930463 |
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NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077
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G |
Srpra |
SRP receptor subunit alpha |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SRPRA mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 8:33,560,365...33,566,458
Ensembl chr 8:33,560,348...33,566,470
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G |
Stat3 |
signal transducer and activator of transcription 3 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of STAT3 mRNA] |
CTD |
PMID:11578593 |
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NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
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G |
Syp |
synaptophysin |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [resveratrol results in increased expression of SYP mRNA] |
CTD |
PMID:21161674 |
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NCBI chr X:14,849,444...14,864,553
Ensembl chr X:14,849,444...14,864,745
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid affects the reaction [Doxorubicin results in increased expression of TGFB1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat affects the expression of TGFB1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of TGFB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of TGFB1 mRNA] |
CTD |
PMID:11124598 PMID:12472797 PMID:19272247 PMID:19639047 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Th |
tyrosine hydroxylase |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid affects the reaction [GPX1 protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein] |
CTD |
PMID:34082047 |
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NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of TIMP1 mRNA] |
CTD |
PMID:12472797 PMID:19272247 |
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NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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G |
Timp2 |
TIMP metallopeptidase inhibitor 2 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [Thioacetamide results in increased expression of TIMP2 protein] |
CTD |
PMID:15078482 |
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NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
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G |
Tinf2 |
TERF1 interacting nuclear factor 2 |
decreases expression |
ISO |
pyrrolidine dithiocarbamic acid results in decreased expression of TINF2 mRNA |
CTD |
PMID:21731707 |
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NCBI chr15:29,170,663...29,178,015
Ensembl chr15:29,170,652...29,176,984
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G |
Tnf |
tumor necrosis factor |
multiple interactions decreases secretion increases stability decreases expression |
ISO EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ethanol results in increased expression of and results in increased secretion of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of MMP1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in decreased expression of CYP1A1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased expression of MMP1 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of Dinoprostone]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of IL6 protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of Nitric Oxide]]; pyrrolidine dithiocarbamic acid results in decreased susceptibility to [TNF protein co-treated with IFNG protein] pyrrolidine dithiocarbamic acid results in decreased secretion of TNF protein pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Oxygen deficiency results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Platelet Activating Factor results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of MADCAM1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased expression of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased secretion of TNF protein]; pyrrolidine dithiocarbamic acid promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein] pyrrolidine dithiocarbamic acid inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of TNF protein] pyrrolidine dithiocarbamic acid results in increased stability of TNF mRNA pyrrolidine dithiocarbamic acid results in decreased expression of TNF mRNA |
CTD |
PMID:8903404 PMID:9756946 PMID:10416616 PMID:10495789 PMID:10653605 PMID:10878378 PMID:10921504 PMID:11006087 PMID:11578593 PMID:11675405 PMID:11699074 PMID:11970852 PMID:12131776 PMID:12388057 PMID:12879239 PMID:14572618 PMID:15161907 PMID:16112155 PMID:16129981 PMID:18039960 PMID:18500357 PMID:21565208 PMID:23535185 PMID:25559736 PMID:25766886 PMID:30796934 PMID:31586597 PMID:32613688 PMID:33161052 More...
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfrsf1b |
TNF receptor superfamily member 1B |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TNFRSF1B mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
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G |
Tp53 |
tumor protein p53 |
multiple interactions decreases expression |
ISO EXP |
[pyrrolidine dithiocarbamic acid results in increased abundance of Copper] which results in increased oxidation of and results in increased expression of TP53 protein; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid results in increased abundance of Copper] which results in increased oxidation of and results in increased expression of TP53 protein]; pyrrolidine dithiocarbamic acid results in increased oxidation of and results in increased expression of TP53 protein pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization of TRP53 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of TRP53 mRNA] pyrrolidine dithiocarbamic acid results in decreased expression of TP53 protein |
CTD |
PMID:11964141 PMID:16049548 PMID:25559736 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Tpo |
thyroid peroxidase |
multiple interactions decreases expression decreases activity |
EXP |
bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased expression of TPO mRNA]; PAX8 protein inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of TPO promoter] |
CTD |
PMID:11108245 |
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NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199
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G |
Traf1 |
TNF receptor-associated factor 1 |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807
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G |
Trib2 |
tribbles pseudokinase 2 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TRIB2 mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 6:38,545,971...38,570,349
Ensembl chr 6:38,545,975...38,569,370
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G |
Tshb |
thyroid stimulating hormone subunit beta |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [TSHB protein results in increased abundance of Hydrogen Peroxide] |
CTD |
PMID:11108245 |
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NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
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G |
Tslp |
thymic stromal lymphopoietin |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid inhibits the reaction [Glupearl 19S results in increased expression of TSLP mRNA] |
CTD |
PMID:32493875 |
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NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548
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G |
Tyrobp |
transmembrane immune signaling adaptor Tyrobp |
multiple interactions |
ISO |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA] |
CTD |
PMID:15477007 |
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NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
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G |
Uba1 |
ubiquitin-like modifier activating enzyme 1 |
multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid results in decreased activity of and results in decreased ubiquitination of UBA1 protein |
CTD |
PMID:25714994 |
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NCBI chr X:1,508,700...1,530,677
Ensembl chr X:1,508,666...1,530,636
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G |
Ube2l6 |
ubiquitin-conjugating enzyme E2L 6 |
increases expression multiple interactions |
ISO |
pyrrolidine dithiocarbamic acid results in increased expression of UBE2L6 mRNA [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of UBE2L6 mRNA |
CTD |
PMID:15477007 |
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NCBI chr 3:69,873,025...69,888,042
Ensembl chr 3:69,873,424...69,888,048
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G |
Ubl4a |
ubiquitin-like 4A |
multiple interactions |
ISO |
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of UBL4A mRNA |
CTD |
PMID:15477007 |
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NCBI chr X:152,151,242...152,154,094
Ensembl chr X:152,151,460...152,154,069
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
EXP |
pyrrolidine dithiocarbamic acid inhibits the reaction [AGT protein results in increased expression of VCAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [AGT protein results in increased expression of VCAM1 protein] |
CTD |
PMID:10712386 |
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NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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G |
Vim |
vimentin |
multiple interactions decreases expression |
ISO EXP |
[bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of VIM mRNA] pyrrolidine dithiocarbamic acid results in decreased expression of VIM protein |
CTD |
PMID:15477007 PMID:30310660 |
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NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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