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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:pyrrolidine dithiocarbamate
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Accession:CHEBI:78782 term browser browse the term
Definition:A member of the class of dithiocarbamic acids that is the N-dithiocarboxy derivative of pyrrolidine.
Synonyms:exact_synonym: pyrrolidine-1-carbodithioic acid
 related_synonym: 1-Pyrrolidinecarbodithioic acid;   Formula=C5H9NS2;   InChI=1S/C5H9NS2/c7-5(8)6-3-1-2-4-6/h1-4H2,(H,7,8);   InChIKey=VSWDORGPIHIGNW-UHFFFAOYSA-N;   Pyrrolidine dithiocarbamic acid;   Pyrrolidine-N-carbodithioic acid;   SMILES=SC(=S)N1CCCC1;   Tetramethylenedithiocarbamic acid
 xref: CAS:25769-03-3;   Chemspider:58828;   HMDB:HMDB0256998;   LINCS:LSM-3818
 xref_mesh: MESH:C020972
 xref: PMID:21483034;   PMID:24315930;   PMID:24348761;   PMID:24365462;   PMID:24594834;   PMID:24610533;   PMID:24751148;   PMID:24829401;   PMID:28976017;   PMID:30745862;   PMID:31140237;   PMID:32440769;   PMID:33269810;   PMID:33376406;   PMID:34340576;   Reaxys:110285;   Wikipedia:Pyrrolidine_dithiocarbamate


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pyrrolidine dithiocarbamate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1] CTD PMID:10636889 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Thioacetamide results in increased expression of ACTA2 protein] CTD PMID:15078482 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Actb actin, beta multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ACTB mRNA] CTD PMID:15477007 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877 		JBrowse link
G Agt angiotensinogen multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [AGT protein results in increased expression of VCAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [AGT protein results in increased expression of VCAM1 protein] CTD PMID:10712386 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased phosphorylation of AKT1 protein] CTD PMID:24431215 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alb albumin multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [ALB protein results in increased abundance of Hydrogen Peroxide]; pyrrolidine dithiocarbamic acid inhibits the reaction [ALB protein results in increased expression of CCL2 mRNA] CTD PMID:11961005 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of ALDH2 mRNA] CTD PMID:11578593 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G App amyloid beta precursor protein multiple interactions ISO pyrrolidine dithiocarbamic acid results in decreased susceptibility to [APP protein modified form binds to APP protein modified form] CTD PMID:17409235 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Ar androgen receptor multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of AR mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of AR protein] CTD PMID:16139439 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression
multiple interactions		 ISO pyrrolidine dithiocarbamic acid results in decreased expression of ARHGDIA mRNA
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of ARHGDIA mRNA		 CTD PMID:15477007 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023 		JBrowse link
G Arpc2 actin related protein 2/3 complex, subunit 2 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ARPC2 mRNA] CTD PMID:15477007 NCBI chr 9:75,820,782...75,851,471
Ensembl chr 9:75,820,770...75,851,471 		JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO
EXP		 [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of ATF4 mRNA]
[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of ATF4 mRNA]		 CTD PMID:15477007 PMID:20920558 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atp7a ATPase copper transporting alpha decreases expression ISO pyrrolidine dithiocarbamic acid results in decreased expression of ATP7A CTD PMID:25070243 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions EXP [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 mRNA; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 protein] CTD PMID:22085843 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX mRNA; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX protein] CTD PMID:22085843 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases phosphorylation
multiple interactions		 ISO
EXP		 pyrrolidine dithiocarbamic acid results in increased phosphorylation of BCL2 protein
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 mRNA; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 mRNA]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in decreased expression of BCL2 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [resveratrol results in increased expression of BCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of BCL2 mRNA]		 CTD PMID:12482581 PMID:16139439 PMID:20920558 PMID:21161674 PMID:22085843 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2a1 BCL2-related protein A1 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of BCL2A1 mRNA] CTD PMID:15477007 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO
EXP		 pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of BCL2L1 protein]
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2L1 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2L1 protein]		 CTD PMID:18789402 PMID:22085843 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [BDNF protein results in increased expression of SOD2 protein] CTD PMID:22261313 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BIRC3 mRNA] CTD PMID:14527959 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression		 ISO pyrrolidine dithiocarbamic acid inhibits the reaction [resveratrol results in increased expression of BIRC5 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of BIRC5 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Testosterone results in increased expression of BIRC5 protein]
pyrrolidine dithiocarbamic acid results in decreased expression of BIRC5 protein		 CTD PMID:16139439 PMID:21161674 PMID:29541389 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Casp1 caspase 1 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of CASP1 protein modified form] CTD PMID:31586597 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP		 pyrrolidine dithiocarbamic acid inhibits the reaction [Palmitic Acid results in decreased expression of and results in increased cleavage of CASP3 protein]
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP3 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP3 protein; [pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP3 protein]; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of CASP3 protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein]; MAPK1 protein affects the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP3 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CASP3 protein]
[pyrrolidine dithiocarbamic acid binds to Copper] which results in increased activity of CASP3 protein; pyrrolidine dithiocarbamic acid inhibits the reaction [ferruginol results in increased activity of CASP3 protein]		 CTD PMID:10941151 PMID:18671963 PMID:20920558 PMID:21687928 PMID:22085843 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 multiple interactions EXP [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP7 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP7 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP7 protein] CTD PMID:20920558 PMID:22085843 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CASP8 mRNA] CTD PMID:15477007 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions		 ISO
EXP		 pyrrolidine dithiocarbamic acid results in increased activity of CASP9 protein
[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP9 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP9 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased cleavage of CASP9 protein]		 CTD PMID:12198114 PMID:20920558 PMID:22085843 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO
EXP		 bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [ALB protein results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased secretion of CCL2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CCL2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of CCL2 mRNA]		 CTD PMID:11006087 PMID:11961005 PMID:12016129 PMID:12472797 PMID:16129981 More... NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of CCL20 mRNA] CTD PMID:11578593 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCL3 mRNA] CTD PMID:15477007 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CCL4 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CCL4 protein] CTD PMID:16129981 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of CCL5 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA] CTD PMID:10495789 PMID:22225513 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccnd1 cyclin D1 decreases expression
multiple interactions		 EXP
ISO		 pyrrolidine dithiocarbamic acid results in decreased expression of CCND1 protein
pyrrolidine dithiocarbamic acid inhibits the reaction [Shikimic Acid results in increased expression of CCND1 mRNA]		 CTD PMID:14603533 PMID:31048002 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccne1 cyclin E1 decreases expression EXP pyrrolidine dithiocarbamic acid results in decreased expression of CCNE1 protein CTD PMID:14603533 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101 		JBrowse link
G Ccng1 cyclin G1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CCNG1 mRNA] CTD PMID:15477007 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Cct5 chaperonin containing TCP1 subunit 5 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CCT5 mRNA] CTD PMID:15477007 NCBI chr 2:82,591,750...82,602,903
Ensembl chr 2:82,590,630...82,602,930 		JBrowse link
G Cd14 CD14 molecule multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Iron deficiency results in increased expression of CD14 protein] CTD PMID:20368581 NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Cd200 Cd200 molecule multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD200 mRNA] CTD PMID:15477007 NCBI chr11:55,410,166...55,437,527
Ensembl chr11:55,410,196...55,501,648 		JBrowse link
G Cd44 CD44 molecule (Indian blood group) multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CD44 mRNA] CTD PMID:15477007 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cdh17 cadherin 17 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA]; [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CDH17 mRNA; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CDH17 mRNA] CTD PMID:15477007 NCBI chr 5:25,262,820...25,314,884
Ensembl chr 5:25,262,758...25,314,884 		JBrowse link
G Cdk2 cyclin dependent kinase 2 decreases expression EXP pyrrolidine dithiocarbamic acid results in decreased expression of CDK2 protein CTD PMID:14603533 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression EXP pyrrolidine dithiocarbamic acid results in decreased expression of CDK4 protein CTD PMID:14603533 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions		 EXP
ISO		 pyrrolidine dithiocarbamic acid results in increased expression of CDKN1A protein
pyrrolidine dithiocarbamic acid inhibits the reaction [Shikimic Acid results in decreased expression of CDKN1A mRNA]
pyrrolidine dithiocarbamic acid inhibits the reaction [Allylamine results in increased expression of CDKN1A protein]; SB 203580 inhibits the reaction [pyrrolidine dithiocarbamic acid results in increased expression of CDKN1A protein]		 CTD PMID:14603533 PMID:15048878 PMID:31048002 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Allylamine results in increased expression of CDKN1B protein] CTD PMID:15048878 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases response to substance
multiple interactions		 ISO CEBPB results in increased susceptibility to pyrrolidine dithiocarbamic acid
pyrrolidine dithiocarbamic acid promotes the reaction [CEBPB protein binds to LCMT2 promoter]		 CTD PMID:9359698 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of CHUK protein] CTD PMID:11739238 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Clec10a C-type lectin domain containing 10A multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of CLEC10A mRNA] CTD PMID:17342418 NCBI chr10:54,876,244...54,880,439
Ensembl chr10:54,876,260...54,880,435 		JBrowse link
G Cln3 CLN3 lysosomal/endosomal transmembrane protein, battenin multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CLN3 mRNA] CTD PMID:15477007 NCBI chr 1:181,156,071...181,169,458
Ensembl chr 1:181,156,073...181,167,434 		JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [gemcitabine results in increased expression of CNR1 mRNA] CTD PMID:21525939 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [gemcitabine results in increased expression of CNR2 mRNA] CTD PMID:21525939 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548 		JBrowse link
G Cntnap1 contactin associated protein 1 increases expression
multiple interactions		 ISO pyrrolidine dithiocarbamic acid results in increased expression of CNTNAP1 mRNA
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CNTNAP1 mRNA		 CTD PMID:15477007 NCBI chr10:86,109,850...86,125,612
Ensembl chr10:86,111,643...86,125,611 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Thioacetamide results in increased expression of COL1A1 mRNA] CTD PMID:15078482 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions ISO atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of COL1A2 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of COL1A2 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of COL1A2 mRNA]] CTD PMID:34152691 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of COL6A1 mRNA] CTD PMID:15477007 NCBI chr20:11,906,105...11,924,599
Ensembl chr20:11,905,957...11,924,597 		JBrowse link
G Comt catechol-O-methyltransferase multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of COMT mRNA] CTD PMID:15477007 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Cp ceruloplasmin multiple interactions
increases secretion
increases expression		 ISO bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in increased expression of CP protein]; Copper promotes the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; Copper promotes the reaction [pyrrolidine dithiocarbamic acid results in increased expression of CP protein]
pyrrolidine dithiocarbamic acid results in increased secretion of CP protein
pyrrolidine dithiocarbamic acid results in increased expression of CP mRNA; pyrrolidine dithiocarbamic acid results in increased expression of CP protein		 CTD PMID:17032174 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Cpsf1 cleavage and polyadenylation specific factor 1 multiple interactions
increases expression		 ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CPSF1 mRNA
pyrrolidine dithiocarbamic acid results in increased expression of CPSF1 mRNA		 CTD PMID:15477007 NCBI chr 7:108,319,429...108,330,023
Ensembl chr 7:108,319,434...108,329,934 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of CREB1 mRNA CTD PMID:15477007 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crem cAMP responsive element modulator multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of CREM mRNA] CTD PMID:15477007 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989 		JBrowse link
G Ctbp1 C-terminal binding protein 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CTBP1 mRNA] CTD PMID:15477007 NCBI chr14:77,455,580...77,482,821
Ensembl chr14:77,455,696...77,482,821 		JBrowse link
G Cul5 cullin 5 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of CUL5 mRNA] CTD PMID:15477007 NCBI chr 8:54,012,963...54,066,751
Ensembl chr 8:54,016,006...54,066,666 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CXCL1 mRNA] CTD PMID:16129981 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions EXP
ISO		 pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CXCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of CXCL2 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CXCL2 protein]		 CTD PMID:16129981 PMID:21507677 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO
EXP		 [pyrrolidine dithiocarbamic acid binds to Copper] which affects the localization of CYCS protein
[Copper co-treated with pyrrolidine dithiocarbamic acid] affects the localization of CYCS protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which affects the localization of CYCS protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] affects the localization of CYCS protein]		 CTD PMID:18671963 PMID:20920558 PMID:22085843 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in decreased expression of CYP1A1 mRNA]
pyrrolidine dithiocarbamic acid inhibits the reaction [Lead inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lead results in increased expression of CYP1A1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Mercury inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [Copper results in increased expression of CYP1A1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Mercury results in increased expression of CYP1A1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein]		 CTD PMID:9756946 PMID:18078826 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of CYP2A13 mRNA] CTD PMID:23884085 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO
EXP		 pyrrolidine dithiocarbamic acid inhibits the reaction [Fenretinide results in increased expression of DDIT3 protein]
pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of DDIT3 mRNA]		 CTD PMID:16972258 PMID:20920558 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression
multiple interactions		 ISO pyrrolidine dithiocarbamic acid results in increased expression of DNAJB1 mRNA
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of DNAJB1 mRNA		 CTD PMID:15477007 NCBI chr19:24,522,717...24,526,458
Ensembl chr19:24,522,717...24,526,458 		JBrowse link
G Dusp4 dual specificity phosphatase 4 multiple interactions ISO bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of DUSP4 mRNA] CTD PMID:15477007 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138 		JBrowse link
G Egf epidermal growth factor multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased activity of MMP9 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased expression of MMP9 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased expression of PLAU mRNA] CTD PMID:16340751 NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064 		JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO [Copper binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of EGFR protein CTD PMID:18346929 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egr1 early growth response 1 multiple interactions
increases expression		 ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [pyrrolidine dithiocarbamic acid results in increased expression of EGR1 mRNA]; SB 203580 promotes the reaction [pyrrolidine dithiocarbamic acid results in increased expression of EGR1 mRNA] CTD PMID:12482581 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr2 early growth response 2 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of EGR2 mRNA] CTD PMID:15477007 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Egr3 early growth response 3 multiple interactions
increases expression		 ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of EGR3 mRNA
pyrrolidine dithiocarbamic acid results in increased expression of EGR3 mRNA		 CTD PMID:15477007 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 multiple interactions ISO
EXP		 pyrrolidine dithiocarbamic acid inhibits the reaction [pervanadate results in increased cleavage of ERBB4 protein] CTD PMID:9685416 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of F3 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of F3 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of F3 protein] CTD PMID:17141290 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 mRNA]]; atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of FN1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased expression of FN1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of FN1 protein]] CTD PMID:12388107 PMID:34152691 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 ISO
EXP		 bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; Copper promotes the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOS protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of FOS mRNA]
pyrrolidine dithiocarbamic acid results in increased expression of FOS mRNA
pyrrolidine dithiocarbamic acid results in increased expression of FOS protein		 CTD PMID:7539260 PMID:15477007 PMID:17032174 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of FOSL2 mRNA] CTD PMID:15477007 NCBI chr 6:24,297,898...24,319,157
Ensembl chr 6:24,300,956...24,320,034 		JBrowse link
G Fyb1 FYN binding protein 1 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of FYB1 mRNA] CTD PMID:15477007 NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629 		JBrowse link
G G3bp2 G3BP stress granule assembly factor 2 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of MYH7 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of MYH7 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPB protein] CTD PMID:28816235 NCBI chr14:15,932,356...16,020,555
Ensembl chr14:15,987,417...16,020,548 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression EXP pyrrolidine dithiocarbamic acid results in increased expression of GAPDH mRNA CTD PMID:11108245 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gata1 GATA binding protein 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Aclarubicin results in increased expression of GATA1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Butyric Acid results in increased expression of GATA1 mRNA] CTD PMID:10656287 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530 		JBrowse link
G Gfra2 GDNF family receptor alpha 2 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of GFRA2 mRNA] CTD PMID:15477007 NCBI chr15:45,941,841...46,033,715
Ensembl chr15:45,941,828...46,033,714 		JBrowse link
G Gnas GNAS complex locus multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of GNAS mRNA CTD PMID:15477007 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [[1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone binds to and results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein] CTD PMID:22645130 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO pyrrolidine dithiocarbamic acid affects the reaction [GPX1 protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]] CTD PMID:34082047 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation ISO pyrrolidine dithiocarbamic acid results in increased phosphorylation of GSK3B protein CTD PMID:17409235 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gtf2h2 general transcription factor IIH subunit 2 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of GTF2H2C mRNA CTD PMID:15477007 NCBI chr 2:31,623,752...31,652,697
Ensembl chr 2:31,624,678...31,652,592 		JBrowse link
G Gzma granzyme A multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of GZMA mRNA] CTD PMID:12700414 NCBI chr 2:44,740,638...44,752,471
Ensembl chr 2:44,740,569...44,752,493 		JBrowse link
G Gzmb granzyme B multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of GZMB mRNA] CTD PMID:12700414 NCBI chr15:30,343,361...30,346,792
Ensembl chr15:30,173,603...30,346,814 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HADHA mRNA] CTD PMID:15477007 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869 		JBrowse link
G Hars1 histidyl-tRNA synthetase 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HARS1 mRNA] CTD PMID:15477007 NCBI chr18:28,381,649...28,398,699
Ensembl chr18:28,381,655...28,398,740 		JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HCK mRNA] CTD PMID:15477007 NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693 		JBrowse link
G Hmbs hydroxymethylbilane synthase multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Aclarubicin results in increased expression of HMBS mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Butyric Acid results in increased expression of HMBS mRNA] CTD PMID:10656287 NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of HMGB1 mRNA] CTD PMID:15477007 NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565 		JBrowse link
G Hmgcs2 3-hydroxy-3-methylglutaryl-CoA synthase 2 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of HMGCS2 mRNA] CTD PMID:11578593 NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases stability
increases expression		 ISO
EXP		 pyrrolidine dithiocarbamic acid promotes the reaction [Fenretinide results in increased expression of HMOX1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Fenretinide results in increased expression of HMOX1 protein]
pyrrolidine dithiocarbamic acid results in increased stability of HMOX1 mRNA
pyrrolidine dithiocarbamic acid results in increased expression of HMOX1 mRNA; pyrrolidine dithiocarbamic acid results in increased expression of HMOX1 protein
pyrrolidine dithiocarbamic acid promotes the reaction [Copper results in increased expression of HMOX1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Lead results in increased expression of HMOX1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Mercury results in increased expression of HMOX1 mRNA]		 CTD PMID:9837857 PMID:16972258 PMID:18078826 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnrnpul1 heterogeneous nuclear ribonucleoprotein U-like 1 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HNRNPUL1 mRNA CTD PMID:15477007 NCBI chr 1:81,228,404...81,264,121
Ensembl chr 1:81,228,404...81,262,592 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases activity ISO pyrrolidine dithiocarbamic acid results in decreased activity of HSD11B2 protein CTD PMID:22796344 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions EXP [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSP90B1 mRNA] CTD PMID:20920558 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 mRNA; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 protein; pyrazolanthrone inhibits the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased expression of HSPA5 mRNA] CTD PMID:20920558 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions
increases expression		 ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HSPA8 mRNA; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of HSPA8 mRNA]
pyrrolidine dithiocarbamic acid results in increased expression of HSPA8 mRNA		 CTD PMID:15477007 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Hyal3 hyaluronidase 3 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of HYAL3 mRNA CTD PMID:15477007 NCBI chr 8:108,254,385...108,260,020
Ensembl chr 8:108,250,667...108,260,647 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions
decreases expression		 ISO
EXP		 pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of ICAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]
pyrrolidine dithiocarbamic acid results in decreased expression of ICAM1 mRNA		 CTD PMID:10495789 PMID:12131776 PMID:14572618 PMID:16129981 PMID:17416599 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Ifng interferon gamma multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [IFNG protein results in increased abundance of Nitrites]
pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid results in decreased susceptibility to [TNF protein co-treated with IFNG protein]		 CTD PMID:8903404 PMID:12845421 PMID:18039960 PMID:25766886 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifngr2 interferon gamma receptor 2 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IFNGR2 mRNA] CTD PMID:15477007 NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005 		JBrowse link
G Il10 interleukin 10 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Doxorubicin results in increased expression of IL10 mRNA] CTD PMID:11124598 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:15778123 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il17a interleukin 17A multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased activity of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of CXCL8 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of IL6 mRNA] CTD PMID:12016129 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il18 interleukin 18 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of IL18 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of IL18 mRNA] CTD PMID:15178407 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP		 pyrrolidine dithiocarbamic acid affects the reaction [IL1B results in increased expression of CXCL8 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [cobaltous chloride results in increased secretion of IL1B protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ethanol results in increased expression of and results in increased secretion of IL1B protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of FOS mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]
pyrrolidine dithiocarbamic acid inhibits the reaction [[IL1B protein results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased abundance of 8-epi-prostaglandin F2alpha]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of IL1B protein modified form]
pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of IL1B mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased expression of IL1B protein]		 CTD PMID:7539260 PMID:8662662 PMID:11530235 PMID:11578593 PMID:11970852 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]
pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of GZMA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of GZMB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of PRF1 mRNA]		 CTD PMID:12700414 PMID:15477007 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il2rb interleukin 2 receptor subunit beta multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RB mRNA] CTD PMID:15477007 NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054 		JBrowse link
G Il6 interleukin 6 multiple interactions
decreases secretion		 EXP
ISO		 pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
pyrrolidine dithiocarbamic acid results in decreased secretion of IL6 protein
atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [cobaltous chloride results in increased secretion of IL6 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ethanol results in increased expression of and results in increased secretion of IL6 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of IL6 protein]]		 CTD PMID:11970852 PMID:12016129 PMID:21779360 PMID:23535185 PMID:32613688 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of IRF1 protein] CTD PMID:11739238 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Irf4 interferon regulatory factor 4 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IRF4 mRNA] CTD PMID:15477007 NCBI chr17:33,721,800...33,742,570
Ensembl chr17:33,721,811...33,740,070 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 ISO bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]]; Copper promotes the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[JUN protein binds to FOS protein] which results in increased expression of and results in increased activity of CP protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of JUN protein]
pyrrolidine dithiocarbamic acid results in increased expression of JUN mRNA; pyrrolidine dithiocarbamic acid results in increased expression of JUN protein		 CTD PMID:12482581 PMID:15477007 PMID:17032174 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kl Klotho multiple interactions
increases expression		 ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Indican results in decreased expression of KL mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Indican results in decreased expression of KL protein]
pyrrolidine dithiocarbamic acid results in increased expression of KL protein		 CTD PMID:21389697 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080 		JBrowse link
G Klf4 Kruppel like factor 4 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of KLF4 mRNA] CTD PMID:15477007 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Klf6 Kruppel-like factor 6 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of KLF6 mRNA] CTD PMID:15477007 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570 		JBrowse link
G Lcmt2 leucine carboxyl methyltransferase 2 increases expression
multiple interactions
increases response to substance		 ISO pyrrolidine dithiocarbamic acid results in increased expression of LCMT2 mRNA; pyrrolidine dithiocarbamic acid results in increased expression of LCMT2 protein
LCMT2 results in increased susceptibility to [pyrrolidine dithiocarbamic acid co-treated with Fluorouracil]
LCMT2 results in increased susceptibility to pyrrolidine dithiocarbamic acid
pyrrolidine dithiocarbamic acid promotes the reaction [CEBPB protein binds to LCMT2 promoter]		 CTD PMID:9359698 NCBI chr 3:108,099,960...108,102,084
Ensembl chr 3:108,099,961...108,102,084 		JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of LCP1 mRNA] CTD PMID:15477007 NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680 		JBrowse link
G Lif LIF, interleukin 6 family cytokine multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of LIF mRNA] CTD PMID:11578593 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G LOC100125598 metallothionein 1a pseudogene multiple interactions
increases expression		 ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MT1G mRNA
pyrrolidine dithiocarbamic acid results in increased expression of MT1G mRNA		 CTD PMID:15477007 NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135 		JBrowse link
G Ltbp4 latent transforming growth factor beta binding protein 4 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of LTBP4 mRNA] CTD PMID:15477007 NCBI chr 1:82,600,136...82,634,346
Ensembl chr 1:82,600,136...82,632,178 		JBrowse link
G Madcam1 mucosal vascular addressin cell adhesion molecule 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of MADCAM1 protein] CTD PMID:12388057 NCBI chr 7:10,036,301...10,039,703
Ensembl chr 7:10,036,301...10,039,703 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of MAP2K2 mRNA] CTD PMID:15477007 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243 		JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 multiple interactions EXP [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAP2K4 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAP2K4 protein] CTD PMID:22085843 NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases activity		 ISO
EXP		 bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK1 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK1 protein]
pyrrolidine dithiocarbamic acid results in decreased activity of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK1 protein]; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK1 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of MAPK1 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of MAPK1 protein]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of MAPK1 protein]; Glutathione inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of MAPK1 protein]; MAPK1 protein affects the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein]; MAPK1 protein affects the susceptibility to [Copper co-treated with pyrrolidine dithiocarbamic acid]		 CTD PMID:10658192 PMID:15477007 PMID:15557793 PMID:20920558 PMID:22085843 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO
EXP		 bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK3 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased phosphorylation of MAPK3 protein]
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK3 protein]; [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK3 protein; [cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of MAPK3 protein; [pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK3 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK3 protein]; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK3 protein]		 CTD PMID:10941151 PMID:15477007 PMID:15557793 PMID:20920558 PMID:22085843 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases activity		 EXP [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein; [pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK8 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein]; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid co-treated with Copper] results in increased activity of MAPK8 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP3 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP7 protein]; MAPK8 protein promotes the reaction [[cupric chloride binds to pyrrolidine dithiocarbamic acid] which results in increased activity of CASP9 protein]; pyrazolanthrone inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein]
pyrrolidine dithiocarbamic acid results in increased activity of MAPK8 protein		 CTD PMID:10658192 PMID:10941151 PMID:20920558 PMID:22085843 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions EXP
ISO		 [Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK9 protein; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK9 protein]; pyrazolanthrone inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK9 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK9 protein]		 CTD PMID:15557793 PMID:22085843 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mapt microtubule-associated protein tau decreases phosphorylation ISO pyrrolidine dithiocarbamic acid results in decreased phosphorylation of MAPT protein CTD PMID:17409235 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Mir146a microRNA 146a multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[ferrous sulfate co-treated with aluminum sulfate] results in increased expression of MIR146A mRNA] CTD PMID:22099153 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Mlxip MLX interacting protein multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose affects the localization of MLXIP protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [Sucrose affects the localization of MLXIP protein]		 CTD PMID:33930463 NCBI chr12:33,128,524...33,192,300
Ensembl chr12:33,128,520...33,192,374 		JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of MMP1 protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased expression of MMP1 mRNA]] CTD PMID:32613688 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [CPG-oligonucleotide results in increased secretion of MMP13 protein] CTD PMID:23331101 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression
multiple interactions		 ISO
EXP		 pyrrolidine dithiocarbamic acid results in decreased expression of MMP2 mRNA
pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat affects the expression of MMP2 mRNA]		 CTD PMID:19272247 PMID:23566884 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases activity
multiple interactions
decreases expression		 ISO pyrrolidine dithiocarbamic acid results in decreased activity of MMP9 protein
pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased activity of MMP9 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased expression of MMP9 mRNA]
pyrrolidine dithiocarbamic acid results in decreased expression of MMP9 mRNA		 CTD PMID:16340751 PMID:22033475 PMID:23566884 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mpo myeloperoxidase multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased activity of MPO protein] CTD PMID:12879239 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mst1r macrophage stimulating 1 receptor decreases expression ISO pyrrolidine dithiocarbamic acid results in decreased expression of MST1R mRNA CTD PMID:18593918 NCBI chr 8:108,596,100...108,611,389
Ensembl chr 8:108,597,299...108,612,455 		JBrowse link
G Mta1 metastasis associated 1 multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of MTA1 mRNA CTD PMID:15477007 NCBI chr 6:132,178,608...132,217,641
Ensembl chr 6:132,178,853...132,217,641 		JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming multiple interactions ISO atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of MUC5AC mRNA]]; atractylodin promotes the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of MUC5AC protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of MUC5AC mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of MUC5AC protein]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased expression of MUC5AC mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [atractylodin inhibits the reaction [Lipopolysaccharides results in increased secretion of MUC5AC protein]] CTD PMID:34152691 NCBI chr 1:196,864,375...196,896,475
Ensembl chr 1:196,864,336...196,896,475 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
decreases expression		 ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of MYC mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [resveratrol results in increased expression of MYC mRNA]
pyrrolidine dithiocarbamic acid results in decreased expression of MYC		 CTD PMID:15477007 PMID:21161674 PMID:25070243 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myh1 myosin heavy chain 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of MYH1 protein] CTD PMID:24431215 NCBI chr10:51,885,913...51,909,699
Ensembl chr10:51,885,913...51,946,295 		JBrowse link
G Myh7 myosin heavy chain 7 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of MYH7 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of MYH7 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of MYH7 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of MYH7 protein] CTD PMID:28816235 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217 		JBrowse link
G Naa80 N(alpha)-acetyltransferase 80, NatH catalytic subunit multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NAA80 mRNA] CTD PMID:15477007 NCBI chr 8:108,254,314...108,257,564
Ensembl chr 8:108,253,302...108,257,563 		JBrowse link
G Nell1 neural EGFL like 1 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NELL1 mRNA] CTD PMID:15477007 NCBI chr 1:99,709,305...100,573,872
Ensembl chr 1:99,709,793...100,573,860 		JBrowse link
G Nfe2 nuclear factor, erythroid 2 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Aclarubicin results in increased expression of NFE2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Butyric Acid results in increased expression of NFE2 mRNA] CTD PMID:10656287 NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions		 ISO pyrrolidine dithiocarbamic acid results in increased expression of NFE2L2 mRNA
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of NFE2L2 mRNA		 CTD PMID:15477007 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO
EXP		 bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrogen Peroxide results in increased activity of [RELA protein binds to NFKB1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased activity of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NFKB1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased activity of [NFKB1 protein binds to RELA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of NFKB1 protein]		 CTD PMID:10416616 PMID:11006087 PMID:11286985 PMID:11578593 PMID:11739238 More... NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of NFKB2 mRNA] CTD PMID:25559736 NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions
decreases expression		 ISO
EXP		 bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFKBIA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]
pyrrolidine dithiocarbamic acid results in decreased expression of NFKBIA mRNA
pyrrolidine dithiocarbamic acid inhibits the reaction [Ammonium Chloride results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Cadmium Chloride results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [Platelet Activating Factor results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased expression of NFKBIA protein]		 CTD PMID:9434740 PMID:10636889 PMID:10921504 PMID:11006087 PMID:11739238 More... NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Ngf nerve growth factor multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGF protein] CTD PMID:17651887 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Ngfr nerve growth factor receptor multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [pentaacetyl geniposide results in increased expression of NGFR protein] CTD PMID:17651887 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nkg7 natural killer cell granule protein 7 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NKG7 mRNA] CTD PMID:15477007 NCBI chr 1:93,844,748...93,845,975
Ensembl chr 1:93,844,902...93,845,983 		JBrowse link
G Nmi N-myc (and STAT) interactor multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NMI mRNA] CTD PMID:15477007 NCBI chr 3:36,415,607...36,439,716
Ensembl chr 3:36,415,607...36,439,498 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
decreases expression		 ISO
EXP		 pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]
pyrrolidine dithiocarbamic acid results in decreased expression of NOS2 mRNA
pyrrolidine dithiocarbamic acid inhibits the reaction [[Ozone results in increased expression of NOS2 protein] which results in increased chemical synthesis of Nitric Oxide]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ammonium Chloride results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Gentamicins results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ozone results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Pyruvaldehyde results in increased expression of NOS2 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Humic Substances results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased expression of NOS2 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [Resveratrol results in decreased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Resveratrol results in decreased expression of NOS2 protein]		 CTD PMID:7539260 PMID:8662662 PMID:8903404 PMID:9788894 PMID:11530235 More... NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Notch3 notch receptor 3 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of NOTCH3 mRNA] CTD PMID:15477007 NCBI chr 7:11,132,984...11,184,025
Ensembl chr 7:11,133,706...11,184,025 		JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPA protein] CTD PMID:28816235 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Nppb natriuretic peptide B multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [G3BP2 protein results in increased expression of NPPB protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPB mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of NPPB protein] CTD PMID:28816235 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of NR4A3 mRNA] CTD PMID:15477007 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
G Odc1 ornithine decarboxylase 1 multiple interactions
increases expression		 ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of ODC1 mRNA
pyrrolidine dithiocarbamic acid results in increased expression of ODC1 mRNA		 CTD PMID:15477007 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Pax8 paired box 8 multiple interactions
decreases expression
decreases chemical synthesis		 EXP bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased expression of PAX8 mRNA]; PAX8 protein inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of TPO promoter]
pyrrolidine dithiocarbamic acid results in decreased chemical synthesis of PAX8 protein		 CTD PMID:11108245 NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Shikimic Acid results in increased expression of PCNA mRNA] CTD PMID:31048002 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pla2g1b phospholipase A2 group IB multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [PLA2G1B protein results in increased expression of CXCL8 protein] CTD PMID:15528384 NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226 		JBrowse link
G Plau plasminogen activator, urokinase multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [EGF protein results in increased expression of PLAU mRNA] CTD PMID:16340751 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Pnpla4 patatin like phospholipase domain containing 4 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of PNPLA4 mRNA] CTD PMID:15477007 NCBI chr  X:42,313,554...42,318,451
Ensembl chr  X:42,305,373...42,318,552 		JBrowse link
G Pou2f2 POU class 2 homeobox 2 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of POU2F2 mRNA] CTD PMID:15477007 NCBI chr 1:80,682,330...80,769,756
Ensembl chr 1:80,685,741...80,724,261 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha decreases expression ISO pyrrolidine dithiocarbamic acid results in decreased expression of PPP1CA mRNA CTD PMID:15477007 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327 		JBrowse link
G Ppp1r10 protein phosphatase 1, regulatory subunit 10 increases expression
multiple interactions		 ISO pyrrolidine dithiocarbamic acid results in increased expression of PPP1R10 mRNA
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of PPP1R10 mRNA		 CTD PMID:15477007 NCBI chr20:2,822,995...2,838,125
Ensembl chr20:2,822,995...2,837,611 		JBrowse link
G Prf1 perforin 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [IL2 protein results in increased expression of PRF1 mRNA] CTD PMID:12700414 NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO
EXP		 pyrrolidine dithiocarbamic acid inhibits the reaction [cobaltous chloride results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Homocysteine results in increased expression of PTGS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [sodium arsenite results in increased expression of PTGS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PTGS2 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [[IL1B protein results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Humic Substances results in increased expression of PTGS2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of PTGS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]		 CTD PMID:8662662 PMID:11530235 PMID:11835400 PMID:16765938 PMID:17767925 More... NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [RAC1 protein inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [RAC1 protein results in decreased expression of SERPINE1 mRNA] CTD PMID:12719791 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions ISO
EXP		 [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of REL mRNA]
pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides affects the localization of REL protein]		 CTD PMID:11970852 PMID:15477007 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases activity		 ISO
EXP		 pyrrolidine dithiocarbamic acid inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased phosphorylation of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [ferruginol results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Glucose results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrogen Peroxide results in increased activity of [RELA protein binds to NFKB1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [IL17A protein results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Resveratrol affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of [NFKB1 protein binds to RELA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]]; Resveratrol promotes the reaction [pyrrolidine dithiocarbamic acid results in decreased expression of RELA]
pyrrolidine dithiocarbamic acid inhibits the reaction [Gentamicins results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Pyruvaldehyde affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Pyruvaldehyde results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased phosphorylation of and affects the localization of RELA protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of RELA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased activity of [NFKB1 protein binds to RELA protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Sucrose affects the localization of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of RELA protein]
pyrrolidine dithiocarbamic acid results in decreased activity of RELA protein		 CTD PMID:10416616 PMID:11739238 PMID:11961005 PMID:11970852 PMID:12016129 More... NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides affects the localization of RELB protein] CTD PMID:11970852 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507 		JBrowse link
G Rhog ras homolog family member G multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of RHOG mRNA] CTD PMID:15477007 NCBI chr 1:156,618,713...156,630,710
Ensembl chr 1:156,615,349...156,631,257 		JBrowse link
G Rnaset2 ribonuclease T2 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of RNASET2 mRNA] CTD PMID:15477007 NCBI chr 1:52,576,344...52,603,151
Ensembl chr 1:52,585,929...52,603,147 		JBrowse link
G Sart1 spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SART1 mRNA] CTD PMID:15477007 NCBI chr 1:202,690,472...202,699,136
Ensembl chr 1:202,690,459...202,699,136 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions
increases expression		 ISO pyrrolidine dithiocarbamic acid inhibits the reaction [RAC1 protein inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [RAC1 protein results in decreased expression of SERPINE1 mRNA]; pyrrolidine dithiocarbamic acid promotes the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]
pyrrolidine dithiocarbamic acid results in increased expression of SERPINE1 mRNA		 CTD PMID:12719791 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sf3b4 splicing factor 3B subunit 4 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of SF3B4 mRNA] CTD PMID:15477007 NCBI chr 2:183,732,791...183,737,545
Ensembl chr 2:183,732,754...183,737,959 		JBrowse link
G Sftpc surfactant protein C multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in decreased expression of SFTPC protein] CTD PMID:28070109 NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777 		JBrowse link
G Sla src-like adaptor multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLA mRNA] CTD PMID:15477007 NCBI chr 7:98,534,431...98,584,810
Ensembl chr 7:98,535,368...98,584,648 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 increases expression
multiple interactions		 ISO
EXP		 pyrrolidine dithiocarbamic acid results in increased expression of SLC1A2 protein
pyrrolidine dithiocarbamic acid inhibits the reaction [[1-(4-(6-bromobenzo(1,3)dioxol-5-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta(c)quinolin-8-yl)ethanone binds to and results in increased activity of GPER1 protein] which results in increased expression of SLC1A2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A2 protein]		 CTD PMID:17409235 PMID:22645130 PMID:24782323 NCBI chr 3:89,005,129...89,126,498
Ensembl chr 3:89,005,129...89,126,498 		JBrowse link
G Slc1a3 solute carrier family 1 member 3 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A3 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Raloxifene Hydrochloride results in increased expression of SLC1A3 protein] CTD PMID:24782323 NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SLC3A2 mRNA] CTD PMID:15477007 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931 		JBrowse link
G Snrnp70 small nuclear ribonucleoprotein U1 subunit 70 multiple interactions
increases expression		 ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of SNRNP70 mRNA
pyrrolidine dithiocarbamic acid results in increased expression of SNRNP70 mRNA		 CTD PMID:15477007 NCBI chr 1:95,856,039...95,876,434
Ensembl chr 1:95,856,036...95,876,392 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
decreases expression		 ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of SOD1 mRNA
pyrrolidine dithiocarbamic acid results in decreased expression of SOD1 mRNA		 CTD PMID:15477007 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression		 ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [BDNF protein results in increased expression of SOD2 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of SOD2 mRNA]
pyrrolidine dithiocarbamic acid results in increased expression of SOD2 mRNA		 CTD PMID:9434740 PMID:10653605 PMID:12031898 PMID:22261313 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression EXP pyrrolidine dithiocarbamic acid results in decreased expression of SPP1 CTD PMID:21076490 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Srgn serglycin multiple interactions
increases expression		 ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of SRGN mRNA
pyrrolidine dithiocarbamic acid results in increased expression of SRGN mRNA		 CTD PMID:15477007 NCBI chr20:30,442,810...30,479,549
Ensembl chr20:30,442,813...30,457,406 		JBrowse link
G Sri sorcin multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Sucrose results in decreased expression of SRI protein] CTD PMID:33930463 NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077 		JBrowse link
G Srpra SRP receptor subunit alpha multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of SRPRA mRNA] CTD PMID:15477007 NCBI chr 8:33,560,365...33,566,458
Ensembl chr 8:33,560,348...33,566,470 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of STAT3 mRNA] CTD PMID:11578593 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Syp synaptophysin multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [resveratrol results in increased expression of SYP mRNA] CTD PMID:21161674 NCBI chr  X:14,849,444...14,864,553
Ensembl chr  X:14,849,444...14,864,745 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP pyrrolidine dithiocarbamic acid affects the reaction [Doxorubicin results in increased expression of TGFB1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat affects the expression of TGFB1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of TGFB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of TGFB1 mRNA] CTD PMID:11124598 PMID:12472797 PMID:19272247 PMID:19639047 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO pyrrolidine dithiocarbamic acid affects the reaction [GPX1 protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein] CTD PMID:34082047 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Paraquat results in increased expression of TIMP1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Tacrolimus results in increased expression of TIMP1 mRNA] CTD PMID:12472797 PMID:19272247 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [Thioacetamide results in increased expression of TIMP2 protein] CTD PMID:15078482 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
G Tinf2 TERF1 interacting nuclear factor 2 decreases expression ISO pyrrolidine dithiocarbamic acid results in decreased expression of TINF2 mRNA CTD PMID:21731707 NCBI chr15:29,170,663...29,178,015
Ensembl chr15:29,170,652...29,176,984 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases secretion
increases stability
decreases expression		 ISO
EXP		 bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcimycin] results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein co-treated with IL1B protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased expression of NOS2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [deoxynivalenol inhibits the reaction [[IFNG protein co-treated with TNF protein co-treated with IL1B protein] results in increased expression of NOS2 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Ethanol results in increased expression of and results in increased secretion of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of MMP1 protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in decreased expression of CYP1A1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased activity of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased expression of IL6 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased expression of MMP1 mRNA]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of Dinoprostone]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of IL6 protein]]; pyrrolidine dithiocarbamic acid promotes the reaction [rhodojaponin II inhibits the reaction [TNF protein results in increased secretion of Nitric Oxide]]; pyrrolidine dithiocarbamic acid results in decreased susceptibility to [TNF protein co-treated with IFNG protein]
pyrrolidine dithiocarbamic acid results in decreased secretion of TNF protein
pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Oxygen deficiency results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Platelet Activating Factor results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of MADCAM1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of NFKB1 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of RELA protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased expression of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zymosan results in increased secretion of TNF protein]; pyrrolidine dithiocarbamic acid promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
pyrrolidine dithiocarbamic acid inhibits the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Hydrochloric Acid results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Zearalenone results in increased expression of TNF protein]
pyrrolidine dithiocarbamic acid results in increased stability of TNF mRNA
pyrrolidine dithiocarbamic acid results in decreased expression of TNF mRNA		 CTD PMID:8903404 PMID:9756946 PMID:10416616 PMID:10495789 PMID:10653605 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TNFRSF1B mRNA] CTD PMID:15477007 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
decreases expression		 ISO
EXP		 [pyrrolidine dithiocarbamic acid results in increased abundance of Copper] which results in increased oxidation of and results in increased expression of TP53 protein; bathocuproine sulfonate inhibits the reaction [[pyrrolidine dithiocarbamic acid results in increased abundance of Copper] which results in increased oxidation of and results in increased expression of TP53 protein]; pyrrolidine dithiocarbamic acid results in increased oxidation of and results in increased expression of TP53 protein
pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of and affects the localization of TRP53 protein]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Folic Acid co-treated with Sodium Bicarbonate] results in increased expression of TRP53 mRNA]
pyrrolidine dithiocarbamic acid results in decreased expression of TP53 protein		 CTD PMID:11964141 PMID:16049548 PMID:25559736 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tpo thyroid peroxidase multiple interactions
decreases expression
decreases activity		 EXP bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased expression of TPO mRNA]; PAX8 protein inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of TPO promoter] CTD PMID:11108245 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199 		JBrowse link
G Traf1 TNF receptor-associated factor 1 multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]; bathocuproine sulfonate inhibits the reaction [pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA]]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of TRAF1 mRNA] CTD PMID:15477007 NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807 		JBrowse link
G Trib2 tribbles pseudokinase 2 multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TRIB2 mRNA] CTD PMID:15477007 NCBI chr 6:38,545,971...38,570,349
Ensembl chr 6:38,545,975...38,569,370 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [TSHB protein results in increased abundance of Hydrogen Peroxide] CTD PMID:11108245 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559 		JBrowse link
G Tslp thymic stromal lymphopoietin multiple interactions ISO pyrrolidine dithiocarbamic acid inhibits the reaction [Glupearl 19S results in increased expression of TSLP mRNA] CTD PMID:32493875 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp multiple interactions ISO [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of TYROBP mRNA] CTD PMID:15477007 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848 		JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 multiple interactions ISO pyrrolidine dithiocarbamic acid results in decreased activity of and results in decreased ubiquitination of UBA1 protein CTD PMID:25714994 NCBI chr  X:1,508,700...1,530,677
Ensembl chr  X:1,508,666...1,530,636 		JBrowse link
G Ube2l6 ubiquitin-conjugating enzyme E2L 6 increases expression
multiple interactions		 ISO pyrrolidine dithiocarbamic acid results in increased expression of UBE2L6 mRNA
[pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of UBE2L6 mRNA		 CTD PMID:15477007 NCBI chr 3:69,873,025...69,888,042
Ensembl chr 3:69,873,424...69,888,048 		JBrowse link
G Ubl4a ubiquitin-like 4A multiple interactions ISO [pyrrolidine dithiocarbamic acid co-treated with bathocuproine sulfonate] results in increased expression of UBL4A mRNA CTD PMID:15477007 NCBI chr  X:152,151,242...152,154,094
Ensembl chr  X:152,151,460...152,154,069 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions EXP pyrrolidine dithiocarbamic acid inhibits the reaction [AGT protein results in increased expression of VCAM1 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [AGT protein results in increased expression of VCAM1 protein] CTD PMID:10712386 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vim vimentin multiple interactions
decreases expression		 ISO
EXP		 [bathocuproine sulfonate co-treated with pyrrolidine dithiocarbamic acid] inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of VIM mRNA]
pyrrolidine dithiocarbamic acid results in decreased expression of VIM protein		 CTD PMID:15477007 PMID:30310660 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20089
    role 20042
      chemical role 19589
        antioxidant 15678
          radical scavenger 6263
            pyrrolidine dithiocarbamate 215
Path 2
Term Annotations click to browse term
  CHEBI ontology 20089
    subatomic particle 20058
      composite particle 20058
        hadron 20088
          baryon 20088
            nucleon 20088
              atomic nucleus 20088
                atom 20058
                  main group element atom 19960
                    p-block element atom 19990
                      carbon group element atom 19916
                        carbon atom 19909
                          organic molecular entity 19909
                            organic group 18988
                              organic divalent group 18950
                                organodiyl group 18974
                                  thiocarbonyl group 5355
                                    thiocarbonyl compound 5355
                                      dithiocarbamic acids 394
                                        pyrrolidine dithiocarbamate 215
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