Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:N(5)-ethyl-L-glutamine
go back to main search page
Accession:CHEBI:17394 term browser browse the term
Definition:A N(5)-alkylglutamine where the alkyl group is ethyl. It has been isolated from green tea.
Synonyms:exact_synonym: (2S)-2-amino-5-(ethylamino)-5-oxopentanoic acid
 related_synonym: Formula=C7H14N2O3;   InChI=1S/C7H14N2O3/c1-2-9-6(10)4-3-5(8)7(11)12/h5H,2-4,8H2,1H3,(H,9,10)(H,11,12)/t5-/m0/s1;   InChIKey=DATAGRPVKZEWHA-YFKPBYRVSA-N;   L-theanine;   N5-Ethyl-L-glutamine;   SMILES=C(=O)([C@H](CCC(NCC)=O)N)O
 alt_id: CHEBI:12651;   CHEBI:21845;   CHEBI:7397
 xref: CAS:3081-61-6;   HMDB:HMDB0034365;   KEGG:C01047
 xref_mesh: MESH:C026166
 xref: PDBeChem:85G;   PMID:20416364;   PMID:22422488;   PMID:23096008;   PMID:23097345;   PMID:23395732;   PMID:24304633;   Reaxys:1725586;   Wikipedia:L-theanine
 cyclic_relationship: is_tautomer_of CHEBI:58128


show annotations for term's descendants           Sort by:
N(5)-ethyl-L-glutamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn2 cellular communication network factor 2 multiple interactions
decreases expression		 EXP theanine inhibits the reaction [Carbon Tetrachloride results in increased expression of CCN2 protein]
theanine results in decreased expression of CCN2 protein		 CTD PMID:25852135 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccna2 cyclin A2 multiple interactions EXP theanine inhibits the reaction [Carbon Tetrachloride results in increased expression of CCNA2 mRNA] CTD PMID:25852135 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions EXP theanine inhibits the reaction [Carbon Tetrachloride results in increased activity of GGT1 protein] CTD PMID:25852135 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP theanine inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein] CTD PMID:25852135 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Il10 interleukin 10 increases expression
multiple interactions		 EXP theanine results in increased expression of IL10 protein
theanine promotes the reaction [Carbon Tetrachloride results in increased expression of IL10 protein]		 CTD PMID:25852135 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression		 EXP theanine inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B protein]
theanine results in decreased expression of IL1B protein		 CTD PMID:25852135 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions		 EXP theanine results in decreased expression of IL6 protein
theanine inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 protein]		 CTD PMID:25852135 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions EXP theanine affects the reaction [Carbon Tetrachloride results in increased expression of MMP13 protein] CTD PMID:25852135 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases expression
multiple interactions		 EXP theanine results in decreased expression of RELA protein
theanine inhibits the reaction [Carbon Tetrachloride results in increased expression of RELA protein]		 CTD PMID:25852135 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression
multiple interactions		 EXP theanine results in decreased expression of TGFB1 protein
theanine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]; theanine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein]		 CTD PMID:25852135 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19917
    role 19887
      application 19730
        pharmaceutical 19564
          drug 19564
            protective agent 18260
              geroprotector 17385
                N(5)-ethyl-L-glutamine 10
Path 2
Term Annotations click to browse term
  CHEBI ontology 19917
    subatomic particle 19915
      composite particle 19915
        hadron 19915
          baryon 19915
            nucleon 19915
              atomic nucleus 19915
                atom 19915
                  main group element atom 19855
                    main group molecular entity 19855
                      s-block molecular entity 19666
                        hydrogen molecular entity 19668
                          hydrides 19176
                            inorganic hydride 18187
                              pnictogen hydride 18177
                                nitrogen hydride 18090
                                  azane 17896
                                    ammonia 17895
                                      organic amino compound 17895
                                        amino acid 16070
                                          alpha-amino acid 13946
                                            L-alpha-amino acid 12967
                                              glutamine family amino acid 10324
                                                L-glutamic acid 10263
                                                  L-glutamic acid derivative 9418
                                                    L-glutamine derivative 10
                                                      N(5)-alkyl-L-glutamine 10
                                                        N(5)-ethyl-L-glutamine 10
paths to the root