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ONTOLOGY REPORT - ANNOTATIONS


Term:mianserin
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Accession:CHEBI:51137 term browser browse the term
Definition:A dibenzoazepine (specifically 1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine) methyl-substituted on N-2. Closely related to (and now mostly superseded by) the tetracyclic antidepressant mirtazapinean, it is an atypical antidepressant used in the treatment of depression throughout Europe and elsewhere.
Synonyms:exact_synonym: 2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine
 related_synonym: 1,2,3,4,10,14b-Hexahydro-2-methyldibenzo(c,f)pyrazino(1,2-a)azepine;   Formula=C18H20N2;   InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3;   InChIKey=UEQUQVLFIPOEMF-UHFFFAOYSA-N;   SMILES=CN1CCN2C(C1)c1ccccc1Cc1ccccc21;   mianserina;   mianserine;   mianserinum
 xref: Beilstein:755346 "Beilstein";   CAS:24219-97-4 "ChemIDplus";   DrugBank:DB06148;   Drug_Central:1796 "DrugCentral";   LINCS:LSM-1374
 xref_mesh: MESH:D008803
 xref: PMID:20825390 "Europe PMC";   Patent:NL6603256;   Patent:US3534041;   Wikipedia:Mianserin


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mianserin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora1 adenosine A1 receptor JBrowse link 13 51,042,111 51,076,913 RGD:6480464
G Comt catechol-O-methyltransferase JBrowse link 11 86,715,981 86,735,630 RGD:6480464
G Fgf4 fibroblast growth factor 4 JBrowse link 1 218,024,537 218,029,539 RGD:6480464
G Gsc goosecoid homeobox JBrowse link 6 128,147,181 128,149,220 RGD:6480464
G Htr2a 5-hydroxytryptamine receptor 2A JBrowse link 15 56,666,152 56,732,469 RGD:6480464
G Htr2c 5-hydroxytryptamine receptor 2C JBrowse link X 118,084,520 118,318,040 RGD:6480464
G Htr7 5-hydroxytryptamine receptor 7 JBrowse link 1 254,547,964 254,671,811 RGD:6480464
G Id2 inhibitor of DNA binding 2 JBrowse link 6 44,360,077 44,361,908 RGD:6480464
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 JBrowse link 3 41,019,898 41,181,070 RGD:6480464
G Kcnj5 potassium inwardly-rectifying channel, subfamily J, member 5 JBrowse link 8 33,435,493 33,463,410 RGD:6480464
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 JBrowse link 11 35,011,007 35,262,362 RGD:6480464
G Prkca protein kinase C, alpha JBrowse link 10 96,186,509 96,585,168 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
G Slc22a6 solute carrier family 22 member 6 JBrowse link 1 224,824,809 224,833,284 RGD:6480464
G Slc6a15 solute carrier family 6 member 15 JBrowse link 7 45,328,207 45,381,920 RGD:6480464
G Sox17 SRY-box transcription factor 17 JBrowse link 5 14,890,318 14,895,907 RGD:6480464
G Tac1 tachykinin, precursor 1 JBrowse link 4 33,638,853 33,646,819 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19657
    role 19601
      biological role 19599
        pharmacological role 18680
          neurotransmitter agent 16228
            adrenergic agent 7903
              adrenergic uptake inhibitor 2997
                mianserin 17
                  mianserin hydrochloride 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19657
    subatomic particle 19653
      composite particle 19653
        hadron 19653
          baryon 19653
            nucleon 19653
              atomic nucleus 19653
                atom 19653
                  main group element atom 19534
                    p-block element atom 19534
                      p-block molecular entity 19534
                        carbon group molecular entity 19417
                          organic molecular entity 19409
                            organic molecule 19332
                              organic cyclic compound 19083
                                organic heterocyclic compound 18154
                                  organic heteropolycyclic compound 17419
                                    organic heterotricyclic compound 13729
                                      dibenzoazepine 2135
                                        mianserin 17
                                          mianserin hydrochloride 0
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