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ONTOLOGY REPORT - ANNOTATIONS


Term:ibuprofen
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Accession:CHEBI:5855 term browser browse the term
Definition:A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(2-methylpropyl)phenyl group.
Synonyms:exact_synonym: 2-[4-(2-methylpropyl)phenyl]propanoic acid
 related_synonym: (+-)-2-(p-isobutylphenyl)propionic acid;   (+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid;   (4-isobutylphenyl)-alpha-methylacetic acid;   (RS)-ibuprofen;   2-(4-isobutylphenyl)propanoic acid;   4-isobutylhydratropic acid;   Adran;   Advil;   Amibufen;   Anco;   Anflagen;   Apsifen;   Bluton;   Brufen;   Brufort;   Buburone;   Butylenin;   Dolgin;   Dolgirid;   Dolgit;   Dolo-Dolgit;   Ebufac;   Epobron;   Femadon;   Formula=C13H18O2;   Haltran;   Ibu-Attritin;   Ibumetin;   Ibuprocin;   Ibutid;   InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15);   InChIKey=HEFNNWSXXWATRW-UHFFFAOYSA-N;   Inabrin;   Inoven;   Lamidon;   Lebrufen;   Liptan;   Medipren;   Motrin;   Mynosedin;   Nobfen;   Nobgen;   Nuprin;   Nurofen;   Pediaprofen;   Roidenin;   Rufen;   SMILES=CC(C)Cc1ccc(cc1)C(C)C(O)=O;   Seclodin;   Suspren;   Tabalon;   Trendar;   Urem;   alpha-(4-isobutylphenyl)propionic acid;   alpha-(p-isobutylphenyl)propionic acid;   p-Isobutylhydratropic acid
 xref: Beilstein:2049713 "ChemIDplus";   CAS:15687-27-1 "ChemIDplus";   CAS:15687-27-1 "KEGG COMPOUND";   CAS:15687-27-1 "NIST Chemistry WebBook";   DrugBank:DB01050;   Drug_Central:1407 "DrugCentral";   HMDB:HMDB0001925;   KEGG:C01588;   KEGG:D00126;   LINCS:LSM-1354
 xref_mesh: MESH:D007052
 xref: PMID:11433218 "Europe PMC";   PMID:12723739 "Europe PMC";   PMID:14562167 "Europe PMC";   PMID:15506544 "Europe PMC";   PMID:16176022 "Europe PMC";   PMID:18335846 "Europe PMC";   PMID:18697608 "Europe PMC";   PMID:21368281 "Europe PMC";   PMID:24168233 "Europe PMC";   PMID:25708941 "Europe PMC";   PMID:25915907 "Europe PMC";   PMID:29756342 "Europe PMC";   Patent:GB971700;   Patent:US3228831;   Patent:US3385886;   Patent:US5215755;   Patent:US6727286;   Reaxys:2049713 "Reaxys";   Wikipedia:Ibuprofen
 cyclic_relationship: is_conjugate_acid_of CHEBI:132922


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ibuprofen term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcb11 ATP binding cassette subfamily B member 11 JBrowse link 3 55,480,024 55,587,946 RGD:6480464
G Abcb9 ATP binding cassette subfamily B member 9 JBrowse link 12 37,923,974 37,956,678 RGD:6480464
G Abcg1 ATP binding cassette subfamily G member 1 JBrowse link 20 9,743,269 9,842,735 RGD:6480464
G Abhd4 abhydrolase domain containing 4 JBrowse link 15 32,888,233 32,906,861 RGD:6480464
G Acox1 acyl-CoA oxidase 1 JBrowse link 10 104,724,534 104,748,003 RGD:6480464
G Acsl1 acyl-CoA synthetase long-chain family member 1 JBrowse link 16 48,937,456 49,003,898 RGD:6480464
G Acsl6 acyl-CoA synthetase long-chain family member 6 JBrowse link 10 39,654,771 39,717,592 RGD:6480464
G Adamts8 ADAM metallopeptidase with thrombospondin type 1 motif, 8 JBrowse link 8 32,017,684 32,037,529 RGD:6480464
G Adcy1 adenylate cyclase 1 JBrowse link 14 87,311,970 87,429,880 RGD:6480464
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:6480464
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:6480464
G Aifm2 apoptosis inducing factor, mitochondria associated 2 JBrowse link 20 31,329,047 31,353,548 RGD:6480464
G Ak4 adenylate kinase 4 JBrowse link 5 120,250,318 120,309,153 RGD:6480464
G Akr1c2 aldo-keto reductase family 1, member C2 JBrowse link 17 69,388,337 69,435,160 RGD:6480464
G Akr1c3 aldo-keto reductase family 1, member C3 JBrowse link 17 69,761,126 69,778,021 RGD:6480464
G Alb albumin JBrowse link 14 19,176,275 19,191,793 RGD:6480464
G Aldoa aldolase, fructose-bisphosphate A JBrowse link 1 198,228,387 198,233,988 RGD:6480464
G Alox12b arachidonate 12-lipoxygenase, 12R type JBrowse link 10 55,744,646 55,756,524 RGD:6480464
G Aloxe3 arachidonate lipoxygenase 3 JBrowse link 10 55,711,996 55,735,915 RGD:6480464
G Amacr alpha-methylacyl-CoA racemase JBrowse link 2 60,949,276 60,961,342 RGD:6480464
G Ambp alpha-1-microglobulin/bikunin precursor JBrowse link 5 78,975,690 78,986,021 RGD:6480464
G Angptl4 angiopoietin-like 4 JBrowse link 7 18,627,814 18,634,043 RGD:6480464
G Anxa1 annexin A1 JBrowse link 1 237,893,983 237,910,002 RGD:6480464
G Anxa2 annexin A2 JBrowse link 8 75,687,134 75,723,589 RGD:6480464
G Anxa3 annexin A3 JBrowse link 14 14,371,921 14,426,503 RGD:6480464
G Anxa9 annexin A9 JBrowse link 2 196,470,318 196,481,568 RGD:6480464
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:6480464
G Arfgef2 ADP ribosylation factor guanine nucleotide exchange factor 2 JBrowse link 3 163,570,435 163,656,612 RGD:6480464
G Asic1 acid sensing ion channel subunit 1 JBrowse link 7 141,324,714 141,354,937 RGD:6480464
G Asic2 acid sensing ion channel subunit 2 JBrowse link 10 68,247,800 69,347,223 RGD:6480464
G Asic3 acid sensing ion channel subunit 3 JBrowse link 4 7,287,868 7,293,295 RGD:6480464
G Asns asparagine synthetase (glutamine-hydrolyzing) JBrowse link 4 33,742,876 33,761,106 RGD:6480464
G Atf4 activating transcription factor 4 JBrowse link 7 121,480,723 121,482,781 RGD:6480464
G Atxn1 ataxin 1 JBrowse link 17 19,160,986 19,533,814 RGD:6480464
G Bace1 beta-secretase 1 JBrowse link 8 50,140,092 50,162,388 RGD:6480464
G Bcat2 branched chain amino acid transaminase 2 JBrowse link 1 101,553,900 101,572,103 RGD:6480464
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:6480464
G Bnip3 BCL2 interacting protein 3 JBrowse link 1 211,248,098 211,265,282 RGD:6480464
G C3 complement C3 JBrowse link 9 9,721,137 9,747,084 RGD:6480464
G Cacna2d3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 JBrowse link 16 4,871,348 5,795,825 RGD:6480464
G Calca calcitonin-related polypeptide alpha JBrowse link 1 184,184,018 184,188,922 RGD:6480464
G Camk2a calcium/calmodulin-dependent protein kinase II alpha JBrowse link 18 56,193,978 56,295,869 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Ccl3 C-C motif chemokine ligand 3 JBrowse link 10 70,869,516 70,871,066 RGD:6480464
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:6480464
G Ccne2 cyclin E2 JBrowse link 5 24,434,077 24,446,406 RGD:6480464
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:6480464
G Cdh3 cadherin 3 JBrowse link 19 38,668,957 38,719,801 RGD:6480464
G Cdk6 cyclin-dependent kinase 6 JBrowse link 4 27,781,728 27,969,653 RGD:6480464
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:6480464
G Cdsn corneodesmosin JBrowse link 20 3,704,626 3,707,266 RGD:6480464
G Ceacam1 CEA cell adhesion molecule 1 JBrowse link 1 82,327,955 82,344,345 RGD:6480464
G Cers5 ceramide synthase 5 JBrowse link 7 141,386,391 141,424,375 RGD:6480464
G Chuk component of inhibitor of nuclear factor kappa B kinase complex JBrowse link 1 263,848,829 263,884,354 RGD:6480464
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:6480464
G Cmbl carboxymethylenebutenolidase homolog JBrowse link 2 84,645,084 84,666,836 RGD:6480464
G Cnr1 cannabinoid receptor 1 JBrowse link 5 49,307,584 49,333,064 RGD:6480464
G Cnr2 cannabinoid receptor 2 JBrowse link 5 154,242,010 154,268,126 RGD:6480464
G Coch cochlin JBrowse link 6 72,359,702 72,373,710 RGD:6480464
G Col11a1 collagen type XI alpha 1 chain JBrowse link 2 216,863,423 217,056,523 RGD:6480464
G Cth cystathionine gamma-lyase JBrowse link 2 264,266,959 264,293,040 RGD:6480464
G Ctsc cathepsin C JBrowse link 1 151,918,514 151,949,979 RGD:6480464
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link 19 10,644,267 10,654,861 RGD:6480464
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link 14 17,210,733 17,212,930 RGD:6480464
G Cxcl2 C-X-C motif chemokine ligand 2 JBrowse link 14 18,731,346 18,733,391 RGD:6480464
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 JBrowse link 1 257,676,172 258,004,428 RGD:6480464
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 JBrowse link 1 147,236,480 147,307,988 RGD:6480464
G Ddx1 DEAD-box helicase 1 JBrowse link 6 38,422,892 38,453,762 RGD:6480464
G Defb4 defensin beta 4 JBrowse link 16 75,634,598 75,637,789 RGD:6480464
G Dhx37 DEAH-box helicase 37 JBrowse link 12 36,594,058 36,614,165 RGD:6480464
G Dlg4 discs large MAGUK scaffold protein 4 JBrowse link 10 56,625,845 56,655,543 RGD:6480464
G Dlgap2 DLG associated protein 2 JBrowse link 16 79,872,238 80,596,977 RGD:6480464
G Dnajb2 DnaJ heat shock protein family (Hsp40) member B2 JBrowse link 9 82,436,453 82,444,669 RGD:6480464
G Dnajc5b DnaJ heat shock protein family (Hsp40) member C5 beta JBrowse link 2 104,290,726 104,382,846 RGD:6480464
G Dnmbp dynamin binding protein JBrowse link 1 263,625,503 263,718,784 RGD:6480464
G Dnmt3a DNA methyltransferase 3 alpha JBrowse link 6 28,205,375 28,346,052 RGD:6480464
G Dpp9 dipeptidyl peptidase 9 JBrowse link 9 10,846,493 10,882,560 RGD:6480464
G Dsc1 desmocollin 1 JBrowse link 18 11,877,918 11,906,828 RGD:6480464
G Dusp22 dual specificity phosphatase 22 JBrowse link 17 34,986,589 35,037,297 RGD:6480464
G Dusp5 dual specificity phosphatase 5 JBrowse link 1 274,245,184 274,258,595 RGD:6480464
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:6480464
G Eif1 eukaryotic translation initiation factor 1 JBrowse link 10 88,227,455 88,229,546 RGD:6480464
G Eif4e eukaryotic translation initiation factor 4E JBrowse link 2 243,819,616 243,853,987 RGD:6480464
G Elavl1 ELAV like RNA binding protein 1 JBrowse link 12 2,461,502 2,502,432 RGD:6480464
G Elf4 E74 like ETS transcription factor 4 JBrowse link X 135,239,626 135,284,330 RGD:6480464
G Elk4 ETS transcription factor ELK4 JBrowse link 13 48,788,262 48,813,267 RGD:6480464
G Eno1 enolase 1 JBrowse link 5 167,288,223 167,299,610 RGD:6480464
G Epas1 endothelial PAS domain protein 1 JBrowse link 6 10,306,508 10,385,239 RGD:6480464
G Ephb6 Eph receptor B6 JBrowse link 4 70,903,253 70,918,514 RGD:6480464
G Eprs glutamyl-prolyl-tRNA synthetase JBrowse link 13 103,300,911 103,371,651 RGD:6480464
G Erbb4 erb-b2 receptor tyrosine kinase 4 JBrowse link 9 75,021,790 76,178,936 RGD:6480464
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit JBrowse link 4 77,284,404 77,347,011 RGD:6480464
G F3 coagulation factor III, tissue factor JBrowse link 2 225,310,686 225,322,281 RGD:6480464
G Faah fatty acid amide hydrolase JBrowse link 5 134,852,899 134,872,095 RGD:6480464
G Fabp4 fatty acid binding protein 4 JBrowse link 2 93,792,666 93,797,267 RGD:6480464
G Fam210b family with sequence similarity 210, member B JBrowse link 3 170,354,109 170,364,265 RGD:6480464
G Fam89a family with sequence similarity 89, member A JBrowse link 19 57,502,308 57,514,896 RGD:6480464
G Fas Fas cell surface death receptor JBrowse link 1 252,589,785 252,624,790 RGD:6480464
G Fasn fatty acid synthase JBrowse link 10 109,987,735 110,005,901 RGD:6480464
G Fgf19 fibroblast growth factor 19 JBrowse link 1 218,058,405 218,061,693 RGD:6480464
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit JBrowse link 1 80,214,691 80,221,417 RGD:6480464
G Frzb frizzled-related protein JBrowse link 3 67,635,604 67,668,772 RGD:6480464
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:6480464
G Gbe1 1,4-alpha-glucan branching enzyme 1 JBrowse link 11 7,210,169 7,485,895 RGD:6480464
G Gclc glutamate-cysteine ligase, catalytic subunit JBrowse link 8 85,059,051 85,097,471 RGD:6480464
G Gclm glutamate cysteine ligase, modifier subunit JBrowse link 2 225,827,504 225,847,876 RGD:6480464
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type JBrowse link 8 76,449,078 76,459,431 RGD:6480464
G Gdf15 growth differentiation factor 15 JBrowse link 16 20,555,395 20,557,978 RGD:6480464
G Gfap glial fibrillary acidic protein JBrowse link 10 90,990,762 90,999,435 RGD:6480464
G Got1 glutamic-oxaloacetic transaminase 1 JBrowse link 1 263,246,248 263,269,762 RGD:6480464
G Gpat3 glycerol-3-phosphate acyltransferase 3 JBrowse link 14 10,343,287 10,396,565 RGD:6480464
G Gstt1 glutathione S-transferase theta 1 JBrowse link 20 13,799,102 13,816,527 RGD:6480464
G Gstt2 glutathione S-transferase, theta 2 JBrowse link 20 13,760,810 13,764,481 RGD:6480464
G H1f2 H1.2 linker histone, cluster member JBrowse link 17 43,638,938 43,640,445 RGD:6480464
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:6480464
G Hmgb1 high mobility group box 1 JBrowse link 12 7,082,529 7,090,246 RGD:6480464
G Hpgd 15-hydroxyprostaglandin dehydrogenase JBrowse link 16 37,457,134 37,495,758 RGD:6480464
G Hsf1 heat shock transcription factor 1 JBrowse link 7 117,538,523 117,565,478 RGD:6480464
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:6480464
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:6480464
G Hspa8 heat shock protein family A (Hsp70) member 8 JBrowse link 8 44,989,401 44,993,261 RGD:6480464
G Htatip2 HIV-1 Tat interactive protein 2 JBrowse link 1 105,094,272 105,109,459 RGD:6480464
G Iars1 isoleucyl-tRNA synthetase 1 JBrowse link 17 15,356,016 15,402,680 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Ids iduronate 2-sulfatase JBrowse link 8 69,447,971 69,466,708 RGD:6480464
G Ifng interferon gamma JBrowse link 7 61,337,383 61,341,419 RGD:6480464
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:6480464
G Igkc immunoglobulin kappa constant RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Il17rb interleukin 17 receptor B JBrowse link 16 6,064,287 6,077,978 RGD:6480464
G Il1a interleukin 1 alpha JBrowse link 3 121,824,712 121,836,122 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il1rn interleukin 1 receptor antagonist JBrowse link 3 1,449,778 1,468,624 RGD:6480464
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Insig1 insulin induced gene 1 JBrowse link 4 342,302 350,515 RGD:6480464
G Insm1 INSM transcriptional repressor 1 JBrowse link 3 140,427,961 140,430,467 RGD:6480464
G Itgam integrin subunit alpha M JBrowse link 1 199,495,312 199,545,738 RGD:6480464
G Itgbl1 integrin subunit beta like 1 JBrowse link 15 110,114,148 110,378,970 RGD:6480464
G Lama3 laminin subunit alpha 3 JBrowse link 18 3,704,866 3,941,215 RGD:6480464
G Lars1 leucyl-tRNA synthetase 1 JBrowse link 18 36,524,013 36,579,471 RGD:6480464
G Ldhb lactate dehydrogenase B JBrowse link 4 176,701,980 176,719,999 RGD:6480464
G Ldlr low density lipoprotein receptor JBrowse link 8 22,750,425 22,773,305 RGD:6480464
G Lgals1 galectin 1 JBrowse link 7 120,153,184 120,156,290 RGD:6480464
G Lta lymphotoxin alpha JBrowse link 20 4,851,889 4,854,677 RGD:6480464
G Ltbr lymphotoxin beta receptor JBrowse link 4 157,822,838 157,829,291 RGD:6480464
G Ly9 lymphocyte antigen 9 JBrowse link 13 90,002,779 90,022,346 RGD:6480464
G Mafg MAF bZIP transcription factor G JBrowse link 10 109,802,877 109,811,476 RGD:6480464
G Mal mal, T-cell differentiation protein JBrowse link 3 120,209,647 120,233,655 RGD:6480464
G Mapk11 mitogen-activated protein kinase 11 JBrowse link 7 130,121,678 130,129,199 RGD:6480464
G Mapk14 mitogen activated protein kinase 14 JBrowse link 20 5,933,290 5,995,137 RGD:6480464
G Mapkapk2 MAPK activated protein kinase 2 JBrowse link 13 47,785,157 47,871,684 RGD:6480464
G Mapkapk3 MAPK activated protein kinase 3 JBrowse link 8 116,012,126 116,046,012 RGD:6480464
G Mapre2 microtubule-associated protein, RP/EB family, member 2 JBrowse link 18 14,814,149 15,780,290 RGD:6480464
G Mcl1 MCL1 apoptosis regulator, BCL2 family member JBrowse link 2 197,786,212 197,788,992 RGD:6480464
G Me1 malic enzyme 1 JBrowse link 8 94,256,830 94,368,834 RGD:6480464
G Mmp1 matrix metallopeptidase 1 JBrowse link 8 5,703,206 5,723,593 RGD:6480464
G Mmp13 matrix metallopeptidase 13 JBrowse link 8 5,522,739 5,533,018 RGD:6480464
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:6480464
G Mmp3 matrix metallopeptidase 3 JBrowse link 8 5,676,608 5,698,579 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Mta2 metastasis associated 1 family, member 2 JBrowse link 1 225,140,863 225,149,584 RGD:6480464
G Mtfp1 mitochondrial fission process 1 JBrowse link 14 84,330,223 84,334,063 RGD:6480464
G Mxd1 max dimerization protein 1 JBrowse link 4 118,451,752 118,472,150 RGD:6480464
G Nampt nicotinamide phosphoribosyltransferase JBrowse link 6 52,122,085 52,156,473 RGD:6480464
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 JBrowse link 17 22,984,792 23,179,701 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nfkb1 nuclear factor kappa B subunit 1 JBrowse link 2 240,773,520 240,890,053 RGD:6480464
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6480464
G Ngfr nerve growth factor receptor JBrowse link 10 83,389,828 83,408,061 RGD:6480464
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 JBrowse link 5 151,776,004 151,779,319 RGD:6480464
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:6480464
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 JBrowse link 18 31,728,373 32,704,022 RGD:6480464
G Nuak1 NUAK family kinase 1 JBrowse link 7 25,039,336 25,111,118 RGD:6480464
G P2ry2 purinergic receptor P2Y2 JBrowse link 1 166,031,228 166,045,423 RGD:6480464
G Pabpn1 poly(A) binding protein, nuclear 1 JBrowse link 15 33,555,640 33,560,251 RGD:6480464
G Pank1 pantothenate kinase 1 JBrowse link 1 253,115,400 253,189,643 RGD:6480464
G Pclo piccolo (presynaptic cytomatrix protein) JBrowse link 4 16,454,904 17,058,921 RGD:6480464
G Pdgfa platelet derived growth factor subunit A JBrowse link 12 17,734,141 17,756,186 RGD:6480464
G Pdia5 protein disulfide isomerase family A, member 5 JBrowse link 11 68,493,035 68,578,999 RGD:6480464
G Pdk4 pyruvate dehydrogenase kinase 4 JBrowse link 4 30,546,772 30,556,774 RGD:6480464
G Pdlim1 PDZ and LIM domain 1 JBrowse link 1 259,308,326 259,357,006 RGD:6480464
G Pgam1 phosphoglycerate mutase 1 JBrowse link 1 261,158,204 261,165,814 RGD:6480464
G Pla2g2a phospholipase A2 group IIA JBrowse link 5 157,282,650 157,285,295 RGD:6480464
G Plau plasminogen activator, urokinase JBrowse link 15 3,644,296 3,650,765 RGD:6480464
G Plec plectin JBrowse link 7 117,230,319 117,291,859 RGD:6480464
G Plin2 perilipin 2 JBrowse link 5 104,984,413 105,010,863 RGD:6480464
G Pmepa1 prostate transmembrane protein, androgen induced 1 JBrowse link 3 171,295,630 171,342,662 RGD:6480464
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:6480464
G Podxl podocalyxin-like JBrowse link 4 58,829,049 58,893,353 RGD:6480464
G Pou5f1 POU class 5 homeobox 1 JBrowse link 20 3,747,231 3,751,994 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G Ppia peptidylprolyl isomerase A JBrowse link 14 86,673,775 86,677,443 RGD:6480464
G Ppp1ca protein phosphatase 1 catalytic subunit alpha JBrowse link 1 219,439,953 219,443,570 RGD:6480464
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A JBrowse link 1 101,511,899 101,515,043 RGD:6480464
G Prdx2 peroxiredoxin 2 JBrowse link 19 26,084,816 26,090,095 RGD:6480464
G Prdx6 peroxiredoxin 6 JBrowse link 13 79,077,567 79,088,113 RGD:6480464
G Prkab2 protein kinase AMP-activated non-catalytic subunit beta 2 JBrowse link 2 199,831,990 199,847,623 RGD:6480464
G Ptger3 prostaglandin E receptor 3 JBrowse link 2 263,895,093 263,979,682 RGD:6480464
G Ptgr1 prostaglandin reductase 1 JBrowse link 5 76,110,746 76,129,361 RGD:6480464
G Ptgs1 prostaglandin-endoperoxide synthase 1 JBrowse link 3 15,560,685 15,582,339 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Pxn paxillin JBrowse link 12 46,797,953 46,845,107 RGD:6480464
G Pygl glycogen phosphorylase L JBrowse link 6 92,597,759 92,643,734 RGD:6480464
G Pyy peptide YY (mapped) JBrowse link 10 90,047,989 90,049,155 RGD:6480464
G Ran RAN, member RAS oncogene family JBrowse link 12 31,319,556 31,324,105 RGD:6480464
G Rara retinoic acid receptor, alpha JBrowse link 10 86,838,819 86,884,224 RGD:6480464
G Rb1 RB transcriptional corepressor 1 JBrowse link 15 55,081,582 55,209,060 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Rrp12 ribosomal RNA processing 12 homolog JBrowse link 1 261,106,768 261,140,416 RGD:6480464
G Rsl1d1 ribosomal L1 domain containing 1 JBrowse link 10 4,375,329 4,387,195 RGD:6480464
G Rsrc2 arginine and serine rich coiled-coil 2 JBrowse link 12 38,274,290 38,294,294 RGD:6480464
G Rxra retinoid X receptor alpha JBrowse link 3 6,272,560 6,295,354 RGD:6480464
G S100a9 S100 calcium binding protein A9 JBrowse link 2 190,097,436 190,100,209 RGD:6480464
G Sars1 seryl-tRNA synthetase 1 JBrowse link 2 211,219,743 211,235,475 RGD:6480464
G Sat1 spermidine/spermine N1-acetyl transferase 1 JBrowse link X 43,626,480 43,629,767 RGD:6480464
G Sele selectin E JBrowse link 13 82,355,234 82,365,323 RGD:6480464
G Sesn1 sestrin 1 JBrowse link 20 46,667,116 46,758,306 RGD:6480464
G Sfn stratifin JBrowse link 5 151,823,422 151,824,937 RGD:6480464
G Sh3tc1 SH3 domain and tetratricopeptide repeats 1 JBrowse link 14 80,184,814 80,229,207 RGD:6480464
G Sik1 salt-inducible kinase 1 JBrowse link 20 10,670,747 10,680,279 RGD:6480464
G Slc10a1 solute carrier family 10 member 1 JBrowse link 6 104,617,730 104,631,355 RGD:6480464
G Slc10a2 solute carrier family 10 member 2 JBrowse link 16 90,324,420 90,350,254 RGD:6480464
G Slc15a1 solute carrier family 15 member 1 JBrowse link 15 106,800,081 106,844,668 RGD:6480464
G Slc16a6 solute carrier family 16, member 6 JBrowse link 10 97,733,701 97,758,723 RGD:6480464
G Slc1a4 solute carrier family 1 member 4 JBrowse link 14 104,582,884 104,612,417 RGD:6480464
G Slc1a7 solute carrier family 1 member 7 JBrowse link 5 127,571,114 127,616,033 RGD:6480464
G Slc22a1 solute carrier family 22 member 1 JBrowse link 1 48,273,639 48,300,645 RGD:6480464
G Slc22a25 solute carrier family 22, member 25 JBrowse link 1 224,596,886 224,698,512 RGD:6480464
G Slc22a6 solute carrier family 22 member 6 JBrowse link 1 224,824,809 224,833,284 RGD:6480464
G Slc22a7 solute carrier family 22 member 7 JBrowse link 9 16,925,321 16,931,119 RGD:6480464
G Slc22a8 solute carrier family 22 member 8 JBrowse link 1 224,799,444 224,818,482 RGD:6480464
G Slc25a20 solute carrier family 25 member 20 JBrowse link 8 117,455,308 117,476,762 RGD:6480464
G Slc2a1 solute carrier family 2 member 1 JBrowse link 5 138,154,677 138,182,897 RGD:6480464
G Slc3a2 solute carrier family 3 member 2 JBrowse link 1 224,906,566 224,921,029 RGD:6480464
G Slc5a8 solute carrier family 5 member 8 JBrowse link 7 29,434,175 29,476,807 RGD:6480464
G Slc6a3 solute carrier family 6 member 3 JBrowse link 1 32,323,011 32,363,983 RGD:6480464
G Slc6a9 solute carrier family 6 member 9 JBrowse link 5 136,669,674 136,703,702 RGD:6480464
G Slc7a1 solute carrier family 7 member 1 JBrowse link 12 8,032,775 8,108,972 RGD:6480464
G Slc7a11 solute carrier family 7 member 11 JBrowse link 2 139,453,774 139,528,479 RGD:6480464
G Slc7a5 solute carrier family 7 member 5 JBrowse link 19 54,693,959 54,722,563 RGD:6480464
G Slco1b2 solute carrier organic anion transporter family, member 1B2 JBrowse link 4 175,814,118 175,881,775 RGD:6480464
G Slco2b1 solute carrier organic anion transporter family, member 2b1 JBrowse link 1 164,623,313 164,671,612 RGD:6480464
G Socs3 suppressor of cytokine signaling 3 JBrowse link 10 106,973,863 106,976,969 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Sorl1 sortilin related receptor 1 JBrowse link 8 46,228,077 46,287,171 RGD:6480464
G Srxn1 sulfiredoxin 1 JBrowse link 3 147,608,850 147,614,410 RGD:6480464
G Strbp spermatid perinuclear RNA binding protein JBrowse link 3 21,817,680 21,956,988 RGD:6480464
G Sulf2 sulfatase 2 JBrowse link 3 162,791,349 162,872,984 RGD:6480464
G Sult1e1 sulfotransferase family 1E member 1 JBrowse link 14 22,070,861 22,089,264 RGD:6480464
G Taldo1 transaldolase 1 JBrowse link 1 214,375,555 214,385,886 RGD:6480464
G Tbx21 T-box transcription factor 21 JBrowse link 10 85,032,799 85,049,331 RGD:6480464
G Tet1 tet methylcytosine dioxygenase 1 JBrowse link 20 27,359,122 27,438,039 RGD:6480464
G Tfe3 transcription factor binding to IGHM enhancer 3 JBrowse link X 15,574,579 15,587,826 RGD:6480464
G Tgfb1 transforming growth factor, beta 1 JBrowse link 1 82,480,875 82,497,196 RGD:6480464
G Thbs1 thrombospondin 1 JBrowse link 3 109,862,120 109,873,466 RGD:6480464
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase JBrowse link 2 157,316,293 157,342,979 RGD:6480464
G Tmprss4 transmembrane serine protease 4 JBrowse link 8 49,469,804 49,503,304 RGD:6480464
G Tnc tenascin C JBrowse link 5 79,789,686 79,874,555 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Tnfaip8 TNF alpha induced protein 8 JBrowse link 18 44,664,310 44,779,914 RGD:6480464
G Tnfrsf21 TNF receptor superfamily member 21 JBrowse link 9 20,546,159 20,621,051 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 JBrowse link 5 24,402,895 24,419,651 RGD:6480464
G Tpd52l1 TPD52 like 1 JBrowse link 1 28,454,949 28,578,736 RGD:6480464
G Tpi1 triosephosphate isomerase 1 JBrowse link 4 157,328,375 157,331,905 RGD:6480464
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 JBrowse link 9 95,295,701 95,302,822 RGD:6480464
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 JBrowse link 9 95,285,592 95,302,822 RGD:6480464
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 JBrowse link 9 95,241,609 95,302,822 RGD:6480464
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 JBrowse link 9 95,221,474 95,302,822 RGD:6480464
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 JBrowse link 9 95,161,157 95,302,822 RGD:6480464
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 JBrowse link 14 22,724,399 22,736,148 RGD:6480464
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 JBrowse link 14 22,597,103 22,619,968 RGD:6480464
G Vars1 valyl-tRNA synthetase 1 JBrowse link 20 4,993,539 5,008,259 RGD:6480464
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 2 219,071,193 219,090,931 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464
G Vwce von Willebrand factor C and EGF domains JBrowse link 1 226,687,258 226,717,989 RGD:6480464
G Wars1 tryptophanyl-tRNA synthetase 1 JBrowse link 6 132,771,026 132,802,262 RGD:6480464
G Wdr81 WD repeat domain 81 JBrowse link 10 62,273,817 62,287,213 RGD:6480464
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:6480464
G Yars1 tyrosyl-tRNA synthetase 1 JBrowse link 5 147,375,350 147,403,578 RGD:6480464
G Zmat3 zinc finger, matrin type 3 JBrowse link 2 118,715,229 118,746,109 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19596
    role 19539
      biological role 19537
        xenobiotic 18155
          ibuprofen 290
            carboxyibuprofen 0
            dexibuprofen 0
            ibuproxam 0
            levibuprofen 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19596
    subatomic particle 19592
      composite particle 19592
        hadron 19592
          baryon 19592
            nucleon 19592
              atomic nucleus 19592
                atom 19592
                  main group element atom 19471
                    p-block element atom 19471
                      carbon group element atom 19345
                        carbon atom 19337
                          organic molecular entity 19337
                            organic group 18299
                              organic divalent group 18289
                                organodiyl group 18289
                                  carbonyl group 18176
                                    carbonyl compound 18176
                                      carboxylic acid 17840
                                        monocarboxylic acid 17169
                                          fatty acid 15574
                                            saturated fatty acid 15539
                                              propionic acid 1078
                                                ibuprofen 290
                                                  carboxyibuprofen 0
                                                  dexibuprofen 0
                                                  ibuproxam 0
                                                  levibuprofen 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.