CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: pioglitazone
Accession: CHEBI:8228
browse the term
Definition: A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity.
Synonyms: exact_synonym: 5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione
related_synonym: (+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione; Formula=C19H20N2O3S; InChI=1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23); InChIKey=HYAFETHFCAUJAY-UHFFFAOYSA-N; SMILES=CCc1ccc(CCOc2ccc(CC3SC(=O)NC3=O)cc2)nc1; pioglitazona; pioglitazonum
xref: Beilstein:3595485; CAS:111025-46-8; Chemspider:4663; DrugBank:DB01132; Drug_Central:2179; HMDB:HMDB0015264; KEGG:C07675; KEGG:D08378; LINCS:LSM-1592
xref_mesh: MESH:C060836
xref: PMID:12879407; PMID:14522601; PMID:17628757; PMID:18215232; PMID:20797618; PMID:27842070; PMID:33798599; PMID:33864097; PMID:33983968; PMID:33995271; PMID:34006325; PMID:34009030; Patent:EP193256; Patent:US4687777; Reaxys:3595485; Wikipedia:Pioglitazone
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Abat
4-aminobutyrate aminotransferase
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABAT mRNA
CTD
PMID:27935865
NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
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Abca1
ATP binding cassette subfamily A member 1
affects expression increases expression
ISO
pioglitazone affects the expression of ABCA1 protein pioglitazone results in increased expression of ABCA1 mRNA; pioglitazone results in increased expression of ABCA1 protein
CTD
PMID:15381068 PMID:17961437 PMID:19201410
NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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Abca4
ATP binding cassette subfamily A member 4
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABCA4 mRNA
CTD
PMID:27935865
NCBI chr 2:210,164,813...210,302,069
Ensembl chr 2:210,164,813...210,302,069
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Abca6
ATP binding cassette subfamily A member 6
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABCA6 mRNA
CTD
PMID:27935865
NCBI chr10:95,142,805...95,212,087
Ensembl chr10:95,142,966...95,211,530
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Abca8
ATP binding cassette subfamily A member 8
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABCA8B mRNA
CTD
PMID:27935865
NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988
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Abcb11
ATP binding cassette subfamily B member 11
decreases activity
ISO
pioglitazone results in decreased activity of ABCB11 protein
CTD
PMID:20829430 PMID:22646477 PMID:23956101
NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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Abcb1a
ATP binding cassette subfamily B member 1A
increases expression
ISO
Pioglitazone results in increased expression of ABCB1 mRNA
CTD
PMID:31233785
NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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Abcc9
ATP binding cassette subfamily C member 9
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABCC9 mRNA
CTD
PMID:27935865
NCBI chr 4:175,531,854...175,655,849
Ensembl chr 4:175,532,547...175,655,356
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Abi3bp
ABI family member 3 binding protein
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABI3BP mRNA
CTD
PMID:27935865
NCBI chr11:43,912,187...44,128,888
Ensembl chr11:43,913,043...44,128,929
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Ablim2
actin binding LIM protein family, member 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABLIM2 mRNA
CTD
PMID:27935865
NCBI chr14:74,865,409...74,990,334
Ensembl chr14:74,866,281...74,990,334
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Abra
actin-binding Rho activating protein
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ABRA mRNA
CTD
PMID:27935865
NCBI chr 7:72,970,187...72,974,255
Ensembl chr 7:72,970,186...72,974,255
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Acat1
acetyl-CoA acetyltransferase 1
decreases expression
ISO
pioglitazone results in decreased expression of ACAT1 mRNA
CTD
PMID:15381068
NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
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Acat2
acetyl-CoA acetyltransferase 2
decreases expression
ISO
Pioglitazone results in decreased expression of ACAT2 mRNA
CTD
PMID:30031879
NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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Ace
angiotensin I converting enzyme
multiple interactions
EXP
pioglitazone inhibits the reaction [Streptozocin results in increased expression of ACE mRNA]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of ACE protein]
CTD
PMID:16979161
NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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Ace2
angiotensin converting enzyme 2
increases expression increases secretion
EXP
Pioglitazone results in increased expression of ACE2 protein Pioglitazone results in increased secretion of ACE2 protein
CTD
PMID:24114819 PMID:24558317
NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
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Acod1
aconitate decarboxylase 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of ACOD1 mRNA
CTD
PMID:27935865
NCBI chr15:79,871,819...79,881,101
Ensembl chr15:79,871,827...79,880,529
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Acta1
actin, alpha 1, skeletal muscle
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ACTA1 mRNA
CTD
PMID:27935865
NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742
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Acta2
actin alpha 2, smooth muscle
multiple interactions
EXP ISO
pioglitazone affects the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] pioglitazone inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of ACTA2 mRNA]; pioglitazone inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] Pioglitazone inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]
CTD
PMID:15052691 PMID:16484506 PMID:18513333 PMID:32613381
NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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Actc1
actin, alpha, cardiac muscle 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ACTC1 mRNA
CTD
PMID:27935865
NCBI chr 3:100,811,987...100,817,523
Ensembl chr 3:100,811,987...100,817,523
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Actg2
actin gamma 2, smooth muscle
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ACTG2 mRNA
CTD
PMID:27935865
NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465
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Actn2
actinin alpha 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ACTN2 mRNA
CTD
PMID:27935865
NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622
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Adam23
ADAM metallopeptidase domain 23
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADAM23 mRNA
CTD
PMID:27935865
NCBI chr 9:64,862,649...65,009,718
Ensembl chr 9:64,862,878...65,006,515
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Adam5
ADAM metallopeptidase domain 5
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADAM5 mRNA
CTD
PMID:27935865
NCBI chr16:67,223,095...67,298,733
Ensembl chr16:67,223,143...67,298,737
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Adam9
ADAM metallopeptidase domain 9
multiple interactions
ISO
pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ADAM9 mRNA]
CTD
PMID:20847119
NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917
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Adcy5
adenylate cyclase 5
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADCY5 mRNA
CTD
PMID:27935865
NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974
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Adcyap1r1
ADCYAP receptor type I
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADCYAP1R1 mRNA
CTD
PMID:27935865
NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:84,593,892...84,642,700
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Adhfe1
alcohol dehydrogenase, iron containing, 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADHFE1 mRNA
CTD
PMID:27935865
NCBI chr 5:9,705,966...9,732,580
Ensembl chr 5:9,705,970...9,732,517
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Adipoq
adiponectin, C1Q and collagen domain containing
multiple interactions increases expression decreases expression
ISO EXP
2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone results in increased expression of ADIPOQ mRNA]; [N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of ADIPOQ mRNA; [Sodium Glutamate co-treated with Pioglitazone] results in increased expression of ADIPOQ protein; Pioglitazone promotes the reaction [Palmitates results in increased secretion of ADIPOQ protein]; PPARG protein affects the reaction [Pioglitazone results in increased expression of ADIPOQ mRNA] pioglitazone results in increased expression of ADIPOQ mRNA; pioglitazone results in increased expression of ADIPOQ protein Pioglitazone inhibits the reaction [Dietary Fats results in decreased expression of ADIPOQ protein]; Pioglitazone inhibits the reaction [Fructose results in decreased secretion of ADIPOQ protein] 2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]]; octocrylene inhibits the reaction [Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]; Pioglitazone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein]; T 0070907 inhibits the reaction [Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]] Pioglitazone results in decreased expression of ADIPOQ protein
CTD
PMID:12927809 PMID:18303122 PMID:18513333 PMID:18815186 PMID:19048458 PMID:24622831 PMID:25679220 PMID:27918843 PMID:27935865 PMID:31016361 PMID:32407875 PMID:34864131 More...
NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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Adm
adrenomedullin
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ADM mRNA
CTD
PMID:20847119
NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
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Adora1
adenosine A1 receptor
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ADORA1 mRNA
CTD
PMID:27935865
NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801
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Agbl1
AGBL carboxypeptidase 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AGBL1 mRNA
CTD
PMID:27935865
NCBI chr 1:130,043,914...130,950,739
Ensembl chr 1:130,043,970...130,951,638
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Ager
advanced glycosylation end product-specific receptor
multiple interactions
EXP
Pioglitazone inhibits the reaction [Fructose results in increased expression of AGER protein]
CTD
PMID:25679220
NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
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Agt
angiotensinogen
multiple interactions
EXP
pioglitazone inhibits the reaction [AGT protein results in increased expression of KLF5 mRNA]; pioglitazone inhibits the reaction [AGT protein results in increased expression of KLF5 protein]
CTD
PMID:25874449
NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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Agtr1a
angiotensin II receptor, type 1a
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AGTR1A mRNA
CTD
PMID:27935865
NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
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Agtr2
angiotensin II receptor, type 2
multiple interactions
ISO
[ANGPT2 protein binds to and results in increased activity of AGTR2 protein] promotes the reaction [pioglitazone binds to and results in increased activity of PPARG protein]; [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AGTR2 mRNA
CTD
PMID:15992368 PMID:27935865
NCBI chr X:112,119,876...112,124,060
Ensembl chr X:112,120,228...112,124,057
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Aifm3
apoptosis inducing factor, mitochondria associated 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AIFM3 mRNA
CTD
PMID:27935865
NCBI chr11:83,504,859...83,523,630
Ensembl chr11:83,504,861...83,521,248
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Ajuba
ajuba LIM protein
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of AJUBA mRNA
CTD
PMID:20847119
NCBI chr15:28,019,775...28,031,537
Ensembl chr15:28,019,778...28,030,021
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Alpk3
alpha-kinase 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ALPK3 mRNA
CTD
PMID:27935865
NCBI chr 1:135,014,455...135,062,294
Ensembl chr 1:135,014,499...135,062,302
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Amigo2
adhesion molecule with Ig like domain 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AMIGO2 mRNA
CTD
PMID:27935865
NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695
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Amotl2
angiomotin like 2
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of AMOTL2 mRNA
CTD
PMID:20847119
NCBI chr 8:103,303,368...103,319,161
Ensembl chr 8:103,302,992...103,318,910
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Ampd1
adenosine monophosphate deaminase 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AMPD1 mRNA
CTD
PMID:27935865
NCBI chr 2:190,598,707...190,619,938
Ensembl chr 2:190,598,700...190,619,938
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Angpt2
angiopoietin 2
multiple interactions
ISO
[ANGPT2 protein binds to and results in increased activity of AGTR2 protein] promotes the reaction [pioglitazone binds to and results in increased activity of PPARG protein]
CTD
PMID:15992368
NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804
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Angptl2
angiopoietin-like 2
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ANGPTL2 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ANGPTL2 mRNA]
CTD
PMID:20847119
NCBI chr 3:16,517,185...16,547,024
Ensembl chr 3:16,517,420...16,548,178
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Angptl4
angiopoietin-like 4
increases expression
ISO
Pioglitazone results in increased expression of ANGPTL4 mRNA
CTD
PMID:30031879
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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Ank1
ankyrin 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ANK1 mRNA
CTD
PMID:27935865
NCBI chr16:68,876,294...69,054,963
Ensembl chr16:68,877,504...69,054,759
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Ankrd37
ankyrin repeat domain 37
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ANKRD37 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ANKRD37 mRNA]
CTD
PMID:20847119
NCBI chr16:46,268,933...46,271,971
Ensembl chr16:46,268,443...46,271,963
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Ankrd63
ankyrin repeat domain 63
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ANKRD63 mRNA
CTD
PMID:27935865
NCBI chr 3:105,675,148...105,679,970
Ensembl chr 3:105,663,638...105,682,404
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Ano5
anoctamin 5
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ANO5 mRNA
CTD
PMID:27935865
NCBI chr 1:101,086,490...101,187,547
Ensembl chr 1:101,087,341...101,187,555
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Anos1
anosmin 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of WFDC17 mRNA
CTD
PMID:27935865
NCBI chr10:68,561,954...68,562,801
Ensembl chr10:68,561,954...68,562,801
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Aoc3
amine oxidase, copper containing 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AOC3 mRNA
CTD
PMID:27935865
NCBI chr10:86,272,757...86,280,702
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Ap1s2
adaptor related protein complex 1 subunit sigma 2
decreases expression
ISO
Pioglitazone results in decreased expression of AP1S2 mRNA
CTD
PMID:30031879
NCBI chr X:30,572,746...30,598,961
Ensembl chr X:30,572,751...30,597,262
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Apc2
APC regulator of WNT signaling pathway 2
increases expression
ISO
pioglitazone results in increased expression of APC2 mRNA
CTD
PMID:21347706
NCBI chr 7:9,392,336...9,414,364
Ensembl chr 7:9,392,336...9,414,310
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Apob
apolipoprotein B
decreases expression
ISO
pioglitazone results in decreased expression of APOB protein
CTD
PMID:16324916
NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
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Apoc1
apolipoprotein C1
multiple interactions
ISO
[Ephedrine co-treated with Caffeine co-treated with pioglitazone] results in increased expression of APOC1 protein
CTD
PMID:16324916
NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375
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Apoc2
apolipoprotein C2
multiple interactions
ISO
[Ephedrine co-treated with Caffeine co-treated with pioglitazone] results in decreased expression of APOC2 protein [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of APOC2 mRNA
CTD
PMID:16324916 PMID:27935865
NCBI chr 1:79,329,429...79,334,397
Ensembl chr 1:79,329,428...79,334,476
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Apoc3
apolipoprotein C3
multiple interactions
ISO
[Ephedrine co-treated with Caffeine co-treated with pioglitazone] results in decreased expression of APOC3 protein
CTD
PMID:16324916
NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
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App
amyloid beta precursor protein
decreases expression multiple interactions
ISO
pioglitazone results in decreased expression of APP protein mutant form pioglitazone inhibits the reaction [[IFNG protein co-treated with IL1B protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]; pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]
CTD
PMID:14586007 PMID:15817521 PMID:16407166
NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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Aqp7
aquaporin 7
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AQP7 mRNA
CTD
PMID:27935865
NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642
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Ar
androgen receptor
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AR mRNA
CTD
PMID:27935865
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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Areg
amphiregulin
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of AREG mRNA
CTD
PMID:27935865
NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
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Armcx2
armadillo repeat containing, X-linked 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ARMCX2 mRNA
CTD
PMID:27935865
NCBI chr X:97,980,662...97,985,523
Ensembl chr X:97,980,660...97,985,552
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Art1
ADP-ribosyltransferase 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ART1 mRNA
CTD
PMID:27935865
NCBI chr 1:156,478,096...156,487,172
Ensembl chr 1:156,482,621...156,487,172
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Asb10
ankyrin repeat and SOCS box-containing 10
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ASB10 mRNA
CTD
PMID:27935865
NCBI chr 4:10,630,318...10,644,270
Ensembl chr 4:10,630,448...10,639,060
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Asb14
ankyrin repeat and SOCS box-containing 14
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ASB14 mRNA
CTD
PMID:27935865
NCBI chr16:2,095,567...2,123,259
Ensembl chr16:2,095,644...2,115,135
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Asb5
ankyrin repeat and SOCS box-containing 5
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ASB5 mRNA
CTD
PMID:27935865
NCBI chr16:37,237,869...37,305,207
Ensembl chr16:37,235,405...37,278,109
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Atf3
activating transcription factor 3
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ATF3 mRNA
CTD
PMID:20847119
NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
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Atp1a2
ATPase Na+/K+ transporting subunit alpha 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ATP1A2 mRNA
CTD
PMID:27935865
NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
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Atp2a1
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ATP2A1 mRNA
CTD
PMID:27935865
NCBI chr 1:181,026,606...181,044,859
Ensembl chr 1:181,026,608...181,044,838
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Atp5f1b
ATP synthase F1 subunit beta
decreases expression
ISO
pioglitazone results in decreased expression of ATP5F1B mRNA
CTD
PMID:20860658
NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
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Avpr1a
arginine vasopressin receptor 1A
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of AVPR1A mRNA
CTD
PMID:27935865
NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215
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B4galnt2
beta-1,4-N-acetyl-galactosaminyl transferase 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of B4GALNT2 mRNA
CTD
PMID:27935865
NCBI chr10:80,801,594...80,828,005
Ensembl chr10:80,802,941...80,857,700
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B4galnt3
beta-1,4-N-acetyl-galactosaminyl transferase 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of B4GALNT3 mRNA
CTD
PMID:27935865
NCBI chr 4:153,409,019...153,509,019
Ensembl chr 4:153,409,004...153,509,321
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Bace1
beta-secretase 1
multiple interactions decreases expression decreases activity
ISO
pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of and results in increased activity of BACE1 protein] pioglitazone results in decreased expression of BACE1 mRNA pioglitazone results in decreased activity of BACE1 protein pioglitazone results in decreased expression of BACE1 mRNA; pioglitazone results in decreased expression of BACE1 protein
CTD
PMID:14586007 PMID:15817521 PMID:16407166
NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
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Bax
BCL2 associated X, apoptosis regulator
multiple interactions
EXP
[naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of BAX mRNA]; Pioglitazone inhibits the reaction [Quinolinic Acid results in increased expression of BAX mRNA]
CTD
PMID:30130594
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Bche
butyrylcholinesterase
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of BCHE mRNA
CTD
PMID:27935865
NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
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Bcl11a
BCL11 transcription factor A
decreases expression
ISO
Pioglitazone results in decreased expression of BCL11A mRNA
CTD
PMID:30031879
NCBI chr14:98,029,018...98,124,181
Ensembl chr14:98,030,461...98,124,180
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Bcl2
BCL2, apoptosis regulator
multiple interactions
EXP
[naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in decreased expression of BCL2 mRNA]; Pioglitazone inhibits the reaction [Quinolinic Acid results in decreased expression of BCL2 mRNA]
CTD
PMID:30130594
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bdnf
brain-derived neurotrophic factor
multiple interactions
ISO
Pioglitazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of BDNF protein]
CTD
PMID:32735850
NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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Bend5
BEN domain containing 5
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of BEND5 mRNA
CTD
PMID:27935865
NCBI chr 5:126,290,648...126,336,662
Ensembl chr 5:125,254,956...126,534,367
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Bglap
bone gamma-carboxyglutamate protein
multiple interactions
ISO
Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]
CTD
PMID:32473317
NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
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Bhlha15
basic helix-loop-helix family, member a15
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of BHLHA15 mRNA
CTD
PMID:27935865
NCBI chr12:10,420,465...10,424,641
Ensembl chr12:10,420,467...10,424,713
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Birc3
baculoviral IAP repeat-containing 3
decreases expression
ISO
Pioglitazone results in decreased expression of BIRC3 mRNA
CTD
PMID:30031879
NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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Bmp6
bone morphogenetic protein 6
increases expression
ISO
Pioglitazone results in increased expression of BMP6 mRNA
CTD
PMID:32816093
NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
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Bpifa5
BPI fold containing family A, member 5
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of BPIFA5 mRNA
CTD
PMID:27935865
NCBI chr 3:142,646,103...142,652,884
Ensembl chr 3:142,646,103...142,652,883
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Bpifb1
BPI fold containing family B, member 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of BPIFB1 mRNA
CTD
PMID:27935865
NCBI chr 3:142,672,995...142,706,258
Ensembl chr 3:142,672,995...142,706,256
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Bsg
basigin (Ok blood group)
multiple interactions decreases expression
ISO
2-chloro-5-nitrobenzanilide inhibits the reaction [pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein]]; pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG mRNA]; pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of BSG protein] pioglitazone results in decreased expression of BSG protein
CTD
PMID:16860414 PMID:17007354 PMID:17055343
NCBI chr 7:9,993,170...10,000,387
Ensembl chr 7:9,993,170...10,000,387
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Btn2a2
butyrophilin, subfamily 2, member A2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of BTN2A2 mRNA
CTD
PMID:27935865
NCBI chr17:41,620,807...41,632,621
Ensembl chr17:41,620,839...41,632,618
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Bzw1
basic leucine zipper and W2 domains 1
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of BZW1 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of BZW1 mRNA]
CTD
PMID:20847119
NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430
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C1qtnf7
C1q and TNF related 7
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of C1QTNF7 mRNA
CTD
PMID:27935865
NCBI chr14:67,467,888...67,580,477
Ensembl chr14:67,468,014...67,580,410
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C2h1orf54
similar to human chromosome 1 open reading frame 54
decreases expression
ISO
Pioglitazone results in decreased expression of C1ORF54 mRNA
CTD
PMID:30031879
NCBI chr 2:183,424,989...183,434,713
Ensembl chr 2:183,424,984...183,435,089
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C4a
complement C4A
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of C4A mRNA
CTD
PMID:27935865
NCBI chr20:4,005,731...4,020,083
Ensembl chr20:4,005,731...4,020,080
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C5ar1
complement C5a receptor 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of C5AR1 mRNA
CTD
PMID:27935865
NCBI chr 1:76,948,622...76,959,826
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Cabcoco1
ciliary associated calcium binding coiled-coil 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CABCOCO1 mRNA
CTD
PMID:27935865
NCBI chr20:20,058,492...20,167,973
Ensembl chr20:20,058,454...20,167,725
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Cacna1c
calcium voltage-gated channel subunit alpha1 C
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CACNA1C mRNA
CTD
PMID:27935865
NCBI chr 4:151,764,138...152,379,454
Ensembl chr 4:151,764,138...152,379,648
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Cacna1s
calcium voltage-gated channel subunit alpha1 S
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CACNA1S mRNA
CTD
PMID:27935865
NCBI chr13:47,493,949...47,564,194
Ensembl chr13:47,493,949...47,564,318
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Cacna2d3
calcium voltage-gated channel auxiliary subunit alpha2delta 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CACNA2D3 mRNA
CTD
PMID:27935865
NCBI chr16:4,098,439...4,912,498
Ensembl chr16:4,098,445...4,912,351
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Cadm2
cell adhesion molecule 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CADM2 mRNA
CTD
PMID:27935865
NCBI chr11:4,548,367...5,525,420
Ensembl chr11:4,555,159...5,525,400
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Calhm5
calcium homeostasis modulator family member 5
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CALHM5 mRNA
CTD
PMID:27935865
NCBI chr20:26,066,270...26,072,348
Ensembl chr20:26,066,242...26,072,272
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Car3
carbonic anhydrase 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CAR3 mRNA
CTD
PMID:27935865
NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
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Casp3
caspase 3
multiple interactions
ISO EXP
pioglitazone inhibits the reaction [Galactose results in increased activity of CASP3 protein] [Fenofibrate co-treated with Pioglitazone] inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; [naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of CASP3 mRNA]; Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Pioglitazone inhibits the reaction [Quinolinic Acid results in increased expression of CASP3 mRNA]
CTD
PMID:23795773 PMID:30130594 PMID:36988379
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casq1
calsequestrin 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CASQ1 mRNA
CTD
PMID:27935865
NCBI chr13:84,670,648...84,680,339
Ensembl chr13:84,670,649...84,680,339
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Cat
catalase
multiple interactions
EXP ISO
2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Pioglitazone inhibits the reaction [Quinolinic Acid results in decreased activity of CAT protein]]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Niacinamide] results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [Quinolinic Acid results in decreased activity of CAT protein]; Pioglitazone inhibits the reaction [Streptozocin results in decreased activity of CAT protein] Pioglitazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased activity of CAT protein]
CTD
PMID:20450929 PMID:27350165 PMID:29233026 PMID:29247773 PMID:32735850
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Cav1
caveolin 1
affects expression
ISO
pioglitazone affects the expression of CAV1 protein
CTD
PMID:17961437
NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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Cav3
caveolin 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CAV3 mRNA
CTD
PMID:27935865
NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
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Ccdc159
coiled-coil domain containing 159
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CCDC159 mRNA
CTD
PMID:27935865
NCBI chr 8:20,457,905...20,467,232
Ensembl chr 8:20,457,909...20,466,562
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Ccdc85a
coiled-coil domain containing 85A
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CCDC85A mRNA
CTD
PMID:27935865
NCBI chr14:102,126,574...102,359,207
Ensembl chr14:102,129,029...102,359,058
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Ccl11
C-C motif chemokine ligand 11
multiple interactions
ISO
pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL11 protein]
CTD
PMID:17015710
NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
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Ccl2
C-C motif chemokine ligand 2
multiple interactions
ISO
[Pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CCL2 mRNA; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein] [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CCL2 mRNA
CTD
PMID:20847119 PMID:27935865 PMID:32613381
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccl3
C-C motif chemokine ligand 3
multiple interactions decreases expression
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CCL3 mRNA Pioglitazone results in decreased expression of CCL3 mRNA
CTD
PMID:27935865 PMID:30031879
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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Ccl5
C-C motif chemokine ligand 5
multiple interactions decreases response to substance
ISO
pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of CCL5 protein] pioglitazone results in decreased susceptibility to CCL5 protein
CTD
PMID:17015710 PMID:18158351
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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Ccl7
C-C motif chemokine ligand 7
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CCL7 mRNA
CTD
PMID:27935865
NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
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Ccn2
cellular communication network factor 2
multiple interactions
ISO EXP
[Pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CCN2 mRNA; Pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of CCN2 mRNA] Pioglitazone affects the reaction [Carbon Tetrachloride results in increased expression of CCN2 mRNA]
CTD
PMID:16484506 PMID:20847119
NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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Ccna1
cyclin A1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CCNA1 mRNA
CTD
PMID:27935865
NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157
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Ccna2
cyclin A2
decreases expression
ISO
pioglitazone results in decreased expression of CCNA2 protein
CTD
PMID:15729575
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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Ccnb1
cyclin B1
decreases expression
ISO
pioglitazone results in decreased expression of CCNB1 protein
CTD
PMID:15729575
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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Ccnd1
cyclin D1
decreases expression multiple interactions
ISO
pioglitazone results in decreased expression of CCND1 mRNA; pioglitazone results in decreased expression of CCND1 protein Pioglitazone results in decreased expression of CCND1 mRNA pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of CCND1 protein]
CTD
PMID:17077279 PMID:26643070 PMID:30031879
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Ccnd3
cyclin D3
decreases expression
ISO
pioglitazone results in decreased expression of CCND3 protein
CTD
PMID:15729575
NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371
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Ccne1
cyclin E1
decreases expression
ISO
pioglitazone results in decreased expression of CCNE1 protein
CTD
PMID:15729575
NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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Ccno
cyclin O
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CCNO mRNA
CTD
PMID:27935865
NCBI chr 2:44,630,873...44,633,912
Ensembl chr 2:44,626,369...44,633,914
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Cd36
CD36 molecule
increases expression multiple interactions
ISO EXP
Pioglitazone results in increased expression of CD36 mRNA; Pioglitazone results in increased expression of CD36 protein pioglitazone results in increased expression of CD36 mRNA [pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of CD36 mRNA Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; PPARG protein affects the reaction [Pioglitazone results in increased expression of CD36 protein]
CTD
PMID:15381068 PMID:16484506 PMID:17143554 PMID:19048458 PMID:20723549 PMID:26643070 PMID:28263783 PMID:30031879 PMID:32613381 More...
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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Cd84
CD84 molecule
decreases expression
ISO
Pioglitazone results in decreased expression of CD84 mRNA
CTD
PMID:30031879
NCBI chr13:84,327,580...84,367,153
Ensembl chr13:84,327,553...84,362,076
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Cdc20b
cell division cycle 20B
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CDC20B mRNA
CTD
PMID:27935865
NCBI chr 2:44,688,349...44,738,056
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Cdc42
cell division cycle 42
decreases expression
ISO
Pioglitazone results in decreased expression of CDC42 mRNA
CTD
PMID:32589349
NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111
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Cdk2
cyclin dependent kinase 2
decreases expression
ISO
pioglitazone results in decreased expression of CDK2 protein
CTD
PMID:15729575
NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
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Cdkl1
cyclin dependent kinase like 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CDKL1 mRNA
CTD
PMID:27935865
NCBI chr 6:88,224,154...88,273,434
Ensembl chr 6:88,224,143...88,270,276
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
multiple interactions decreases expression
EXP ISO
pioglitazone inhibits the reaction [2-Acetylaminofluorene inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein]]; pioglitazone promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1A protein] pioglitazone results in decreased expression of CDKN1A protein Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in increased expression of CDKN1A protein]]; Pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of CDKN1A protein]; Pioglitazone inhibits the reaction [Indican results in increased expression of CDKN1A protein]; Pioglitazone promotes the reaction [Melatonin inhibits the reaction [Indican results in increased expression of CDKN1A protein]]; PRNP protein promotes the reaction [Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in increased expression of CDKN1A protein]]]; PRNP protein promotes the reaction [Pioglitazone promotes the reaction [Melatonin inhibits the reaction [Indican results in increased expression of CDKN1A protein]]]
CTD
PMID:15729575 PMID:17582756 PMID:26643070 PMID:29734669
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cdkn1b
cyclin-dependent kinase inhibitor 1B
multiple interactions increases expression
EXP ISO
pioglitazone inhibits the reaction [2-Acetylaminofluorene promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1B protein]]; pioglitazone promotes the reaction [Diethylnitrosamine results in decreased expression of CDKN1B protein] pioglitazone results in increased expression of CDKN1B protein pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased degradation of CDKN1B protein]; PRKAA1 protein affects the reaction [pioglitazone results in increased expression of CDKN1B protein]
CTD
PMID:17582756 PMID:26643070
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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Cdkn1c
cyclin-dependent kinase inhibitor 1C
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of CDKN1C mRNA
CTD
PMID:20847119
NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
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Cebpa
CCAAT/enhancer binding protein alpha
increases expression
ISO
pioglitazone results in increased expression of CEBPA mRNA
CTD
PMID:28242381
NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
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Cemip
cell migration inducing hyaluronidase 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CEMIP mRNA
CTD
PMID:27935865
NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415
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Ces1d
carboxylesterase 1D
increases expression
ISO
pioglitazone results in increased expression of CES1 mRNA
CTD
PMID:15381068
NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
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Cfd
complement factor D
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CFD mRNA
CTD
PMID:27935865
NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
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Chchd6
coiled-coil-helix-coiled-coil-helix domain containing 6
decreases expression
ISO
Pioglitazone results in decreased expression of CHCHD6 mRNA
CTD
PMID:30031879
NCBI chr 4:121,803,501...122,024,209
Ensembl chr 4:121,792,717...122,024,216
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Chi3l1
chitinase 3 like 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in increased expression of CHI3L1 mRNA
CTD
PMID:27935865
NCBI chr13:45,641,802...45,649,787
Ensembl chr13:45,641,802...45,649,787
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Chit1
chitinase 1
decreases expression
ISO
Pioglitazone results in decreased expression of CHIT1 mRNA
CTD
PMID:30031879
NCBI chr13:45,565,841...45,613,593
Ensembl chr13:45,593,845...45,613,592
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Chp2
calcineurin-like EF hand protein 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CHP2 mRNA
CTD
PMID:27935865
NCBI chr 1:176,757,945...176,772,443
Ensembl chr 1:176,757,876...176,772,139
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Chrm1
cholinergic receptor, muscarinic 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CHRM1 mRNA
CTD
PMID:27935865
NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356
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Chrm2
cholinergic receptor, muscarinic 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CHRM2 mRNA
CTD
PMID:27935865
NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
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Chrna1
cholinergic receptor nicotinic alpha 1 subunit
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CHRNA1 mRNA
CTD
PMID:27935865
NCBI chr 3:58,454,763...58,469,832
Ensembl chr 3:58,454,744...58,469,840
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Chrne
cholinergic receptor nicotinic epsilon subunit
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CHRNE mRNA
CTD
PMID:27935865
NCBI chr10:55,331,211...55,339,923
Ensembl chr10:55,331,212...55,335,530
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Chuk
component of inhibitor of nuclear factor kappa B kinase complex
multiple interactions
ISO
[Metformin co-treated with Pioglitazone] results in decreased expression of CHUK mRNA
CTD
PMID:32589349
NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065
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Cidec
cell death-inducing DFFA-like effector c
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CIDEC mRNA
CTD
PMID:27935865
NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
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Ckm
creatine kinase, M-type
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CKM mRNA
CTD
PMID:27935865
NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
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Ckmt2
creatine kinase, mitochondrial 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CKMT2 mRNA
CTD
PMID:27935865
NCBI chr 2:23,079,918...23,110,518
Ensembl chr 2:23,079,918...23,110,430
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Clec14a
C-type lectin domain containing 14A
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CLEC14A mRNA
CTD
PMID:27935865
NCBI chr 6:75,881,470...75,884,612
Ensembl chr 6:75,881,473...75,884,612
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Clec1a
C-type lectin domain family 1, member A
increases expression
ISO
Pioglitazone results in increased expression of CLEC1A mRNA
CTD
PMID:30031879
NCBI chr 4:162,875,360...162,902,571
Ensembl chr 4:162,877,346...162,901,247
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Clec4a3
C-type lectin domain family 4, member A3
decreases expression
ISO
Pioglitazone results in decreased expression of CLEC4A mRNA
CTD
PMID:30031879
NCBI chr 4:156,214,030...156,224,818
Ensembl chr 4:156,214,718...156,224,817
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Clec4d
C-type lectin domain family 4, member D
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CLEC4D mRNA
CTD
PMID:27935865
NCBI chr 4:156,589,591...156,599,279
Ensembl chr 4:156,589,792...156,598,848
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Clec4e
C-type lectin domain family 4, member E
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CLEC4E mRNA
CTD
PMID:27935865
NCBI chr 4:156,606,927...156,612,911
Ensembl chr 4:156,607,614...156,612,767
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Clstn3
calsyntenin 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CLSTN3 mRNA
CTD
PMID:27935865
NCBI chr 4:157,331,494...157,364,769
Ensembl chr 4:157,331,494...157,364,769
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Cmya5
cardiomyopathy associated 5
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CMYA5 mRNA
CTD
PMID:27935865
NCBI chr 2:24,279,520...24,378,253
Ensembl chr 2:24,279,528...24,378,364
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Cnga3
cyclic nucleotide gated channel subunit alpha 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CNGA3 mRNA
CTD
PMID:27935865
NCBI chr 9:39,447,534...39,494,044
Ensembl chr 9:39,448,034...39,493,183
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Cnn1
calponin 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CNN1 mRNA
CTD
PMID:27935865
NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098
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Cnrip1
cannabinoid receptor interacting protein 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CNRIP1 mRNA
CTD
PMID:27935865
NCBI chr14:91,462,877...91,492,739
Ensembl chr14:91,462,647...91,492,735
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Cntd1
cyclin N-terminal domain containing 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CNTD1 mRNA
CTD
PMID:27935865
NCBI chr10:86,221,430...86,231,812
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Cog8
component of oligomeric golgi complex 8
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of COG8 mRNA
CTD
PMID:20847119
NCBI chr19:34,951,625...34,962,377
Ensembl chr19:34,951,627...34,962,397
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Col6a5
collagen type VI alpha 5 chain
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of COL6A5 mRNA
CTD
PMID:27935865
NCBI chr 8:106,483,806...106,584,114
Ensembl chr 8:106,483,799...106,584,113
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Coro6
coronin 6
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CORO6 mRNA
CTD
PMID:27935865
NCBI chr10:62,311,552...62,319,659
Ensembl chr10:62,311,660...62,319,659
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Cox6a2
cytochrome c oxidase subunit 6A2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of COX6A2 mRNA
CTD
PMID:27935865
NCBI chr 1:182,788,528...182,790,746
Ensembl chr 1:182,788,528...182,789,274
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Cpt1a
carnitine palmitoyltransferase 1A
multiple interactions
ISO
Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]
CTD
PMID:32613381
NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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Cpt1b
carnitine palmitoyltransferase 1B
increases expression
ISO
pioglitazone results in increased expression of CPT1B mRNA
CTD
PMID:20723549
NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
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Cpxm1
carboxypeptidase X (M14 family), member 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CPXM1 mRNA
CTD
PMID:27935865
NCBI chr 3:117,588,532...117,595,330
Ensembl chr 3:117,588,532...117,595,330
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Cpz
carboxypeptidase Z
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CPZ mRNA
CTD
PMID:27935865
NCBI chr14:75,223,692...75,246,946
Ensembl chr14:75,223,605...75,246,945
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Creb1
cAMP responsive element binding protein 1
multiple interactions
ISO
Pioglitazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CREB1 protein]
CTD
PMID:32735850
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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Crh
corticotropin releasing hormone
increases expression
ISO
Pioglitazone results in increased expression of CRH mRNA
CTD
PMID:30031879
NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919
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Crhr2
corticotropin releasing hormone receptor 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CRHR2 mRNA
CTD
PMID:27935865
NCBI chr 4:84,222,897...84,265,924
Ensembl chr 4:84,224,002...84,265,904
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Crispld1
cysteine-rich secretory protein LCCL domain containing 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CRISPLD1 mRNA
CTD
PMID:27935865
NCBI chr 5:1,267,347...1,314,926
Ensembl chr 5:1,274,647...1,314,926
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Crp
C-reactive protein
affects expression decreases expression
EXP ISO
pioglitazone affects the expression of CRP protein Pioglitazone results in decreased expression of CRP protein
CTD
PMID:28705172 PMID:28744220
NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
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Cryab
crystallin, alpha B
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of CRYAB mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of CRYAB mRNA]
CTD
PMID:20847119
NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
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Crym
crystallin, mu
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CRYM mRNA
CTD
PMID:27935865
NCBI chr 1:174,560,423...174,575,660
Ensembl chr 1:174,560,416...174,575,633
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Csn1s1
casein alpha s1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CSN1S1 mRNA
CTD
PMID:27935865
NCBI chr14:20,343,620...20,359,614
Ensembl chr14:20,343,619...20,359,614
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Csrp3
cysteine and glycine rich protein 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CSRP3 mRNA
CTD
PMID:27935865
NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653
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Ctla4
cytotoxic T-lymphocyte-associated protein 4
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CTLA4 mRNA
CTD
PMID:27935865
NCBI chr 9:62,318,874...62,325,978
Ensembl chr 9:62,319,312...62,324,963
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Ctnnb1
catenin beta 1
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of CTNNB1 mRNA
CTD
PMID:20847119
NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
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Cxcl12
C-X-C motif chemokine ligand 12
decreases response to substance multiple interactions
ISO
pioglitazone results in decreased susceptibility to CXCL12 protein pioglitazone inhibits the reaction [CXCL12 protein affects the localization of ICAM3 protein] [N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CXCL12 mRNA
CTD
PMID:18158351 PMID:27935865
NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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Cxcl2
C-X-C motif chemokine ligand 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CXCL2 mRNA; [pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of CXCL2 mRNA
CTD
PMID:27935865 PMID:28263783
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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Cxcl3
C-X-C motif chemokine ligand 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of CXCL3 mRNA
CTD
PMID:27935865
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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Cxcl6
C-X-C motif chemokine ligand 6
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in increased expression of CXCL5 mRNA
CTD
PMID:27935865
NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
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Cxcr3
C-X-C motif chemokine receptor 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CXCR3 mRNA
CTD
PMID:27935865
NCBI chr X:66,844,318...66,846,969
Ensembl chr X:66,844,318...66,846,969
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Cxcr4
C-X-C motif chemokine receptor 4
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of CXCR4 mRNA
CTD
PMID:20847119
NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
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Cyba
cytochrome b-245 alpha chain
decreases expression affects activity
ISO
pioglitazone results in decreased expression of CYBA mRNA pioglitazone affects the activity of CYBA protein
CTD
PMID:11172467 PMID:21962020
NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
multiple interactions decreases activity decreases expression
ISO
pioglitazone inhibits the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in increased activity of CYP17A1 protein]; pioglitazone inhibits the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one results in increased expression of CYP17A1 mRNA] pioglitazone results in decreased activity of CYP17A1 protein pioglitazone results in decreased expression of CYP17A1 mRNA
CTD
PMID:15072549 PMID:17138841
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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Cyp2b1
cytochrome P450, family 2, subfamily b, polypeptide 1
increases expression
EXP
pioglitazone results in increased expression of CYP2B1 mRNA
CTD
PMID:16597547
NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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Cyp2b3
cytochrome P450, family 2, subfamily b, polypeptide 3
increases expression
ISO
pioglitazone results in increased expression of CYP2B6 protein Pioglitazone results in increased expression of CYP2B10 mRNA
CTD
PMID:12642470 PMID:28541575
NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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Cyp2c24
cytochrome P450, family 2, subfamily c, polypeptide 24
increases expression
ISO
Pioglitazone results in increased expression of CYP2C55 mRNA
CTD
PMID:28541575
NCBI chr 1:236,873,967...236,936,238
Ensembl chr 1:236,873,967...236,936,238
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Cyp2c79
cytochrome P450, family 2, subfamily c, polypeptide 79
multiple interactions affects metabolic processing decreases activity increases expression
ISO
Gemfibrozil inhibits the reaction [CYP2C8 protein affects the metabolism of pioglitazone] pioglitazone results in decreased activity of CYP2C8 protein Pioglitazone results in increased expression of CYP2C8 mRNA
CTD
PMID:12642470 PMID:15900286 PMID:31233785
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Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CYP2E1 mRNA
CTD
PMID:27935865
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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Cyp2g1
cytochrome P450, family 2, subfamily g, polypeptide 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of CYP2G1 mRNA
CTD
PMID:27935865
NCBI chr 1:82,145,635...82,156,862
Ensembl chr 1:82,145,073...82,156,828
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Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
multiple interactions increases expression affects metabolic processing decreases activity
EXP ISO
pioglitazone inhibits the reaction [Endotoxins results in decreased expression of CYP3A2 protein] [Pioglitazone results in increased expression of CYP3A4 protein] which results in decreased abundance of Ethinyl Estradiol; [Pioglitazone results in increased expression of CYP3A4 protein] which results in decreased abundance of Midazolam; Pioglitazone results in increased expression of and results in increased activity of CYP3A4 protein Pioglitazone results in increased expression of CYP3A4 mRNA; Pioglitazone results in increased expression of CYP3A4 protein CYP3A4 protein affects the metabolism of Pioglitazone Pioglitazone results in decreased activity of CYP3A4 protein
CTD
PMID:12642470 PMID:15364003 PMID:15860655 PMID:15900286 PMID:16837568 PMID:22524704 PMID:31233785 More...
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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Cyp3a23-3a1
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1
increases expression
EXP
Pioglitazone results in increased expression of CYP3A23-3A1 mRNA
CTD
PMID:16597547
NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030 Ensembl chr12:9,254,475...9,285,030
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Cyp7a1
cytochrome P450 family 7 subfamily A member 1
multiple interactions increases expression
ISO
pioglitazone promotes the reaction [U 0126 results in increased expression of CYP7A1 mRNA]; U 0126 promotes the reaction [pioglitazone results in increased expression of CYP7A1 mRNA]
CTD
PMID:22593575
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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Dcaf12l1
DDB1 and CUL4 associated factor 12-like 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DCAF12L1 mRNA
CTD
PMID:27935865
NCBI chr X:123,695,286...123,698,905
Ensembl chr X:123,695,286...123,698,905
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Dcx
doublecortin
multiple interactions
ISO
Pioglitazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of DCX protein]
CTD
PMID:32735850
NCBI chr X:107,430,767...107,573,612
Ensembl chr X:107,430,767...107,507,476
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Ddah1
dimethylarginine dimethylaminohydrolase 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DDAH1 mRNA
CTD
PMID:27935865
NCBI chr 2:234,667,499...234,800,322
Ensembl chr 2:234,667,491...234,799,339
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Ddit4
DNA-damage-inducible transcript 4
multiple interactions increases expression
ISO
[Metformin co-treated with Pioglitazone] results in increased expression of DDIT4 mRNA Pioglitazone results in increased expression of DDIT4 mRNA
CTD
PMID:32589349
NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
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Ddit4l
DNA-damage-inducible transcript 4-like
multiple interactions increases expression
ISO
[Metformin co-treated with Pioglitazone] results in increased expression of DDIT4L mRNA Pioglitazone results in increased expression of DDIT4L mRNA
CTD
PMID:32589349
NCBI chr 2:226,128,273...226,131,044
Ensembl chr 2:226,128,276...226,131,375
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Depp1
DEPP autophagy regulator 1
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of DEPP1 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of DEPP1 mRNA]
CTD
PMID:20847119
NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542
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Deptor
DEP domain containing MTOR-interacting protein
multiple interactions
ISO
[Metformin co-treated with Pioglitazone] results in decreased expression of DEPTOR mRNA
CTD
PMID:32589349
NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773
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Derl3
derlin 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DERL3 mRNA
CTD
PMID:27935865
NCBI chr20:12,754,490...12,768,454
Ensembl chr20:12,763,543...12,767,027
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Des
desmin
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DES mRNA
CTD
PMID:27935865
NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
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Deup1
deuterosome assembly protein 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DEUP1 mRNA
CTD
PMID:27935865
NCBI chr 8:12,380,300...12,442,649
Ensembl chr 8:12,380,302...12,442,199
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Dgat1
diacylglycerol O-acyltransferase 1
increases expression
ISO
pioglitazone results in increased expression of DGAT1 mRNA
CTD
PMID:20723549
NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
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Dgat2
diacylglycerol O-acyltransferase 2
increases expression
ISO
pioglitazone results in increased expression of DGAT2 mRNA
CTD
PMID:20723549
NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
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Dhrs7c
dehydrogenase/reductase 7C
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DHRS7C mRNA
CTD
PMID:27935865
NCBI chr10:52,495,262...52,513,338
Ensembl chr10:52,495,262...52,513,338
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Dio2
iodothyronine deiodinase 2
increases activity multiple interactions increases expression
ISO
pioglitazone results in increased activity of DIO2 protein PPARG protein promotes the reaction [pioglitazone results in increased activity of DIO2 protein] pioglitazone results in increased expression of DIO2 mRNA
CTD
PMID:19036883
NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
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Dio3
iodothyronine deiodinase 3
decreases activity
ISO
pioglitazone results in decreased activity of DIO3 protein
CTD
PMID:19036883
NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
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Dlg1
discs large MAGUK scaffold protein 1
multiple interactions
ISO
pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of DLG1 mRNA]
CTD
PMID:20847119
NCBI chr11:68,911,883...69,103,230
Ensembl chr11:68,911,883...69,102,689
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Dmbt1
deleted in malignant brain tumors 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DMBT1 mRNA
CTD
PMID:27935865
NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478
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Dnaaf2
dynein, axonemal, assembly factor 2
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of DNAAF2 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of DNAAF2 mRNA]
CTD
PMID:20847119
NCBI chr 6:87,661,101...87,670,267
Ensembl chr 6:87,660,821...87,670,199
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Dnah8
dynein, axonemal, heavy chain 8
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DNAH8 mRNA
CTD
PMID:27935865
NCBI chr20:8,692,939...8,946,780
Ensembl chr20:8,692,963...8,946,772
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Dner
delta/notch-like EGF repeat containing
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DNER mRNA
CTD
PMID:27935865
NCBI chr 9:85,586,985...85,902,461
Ensembl chr 9:85,586,987...85,902,637
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Dpt
dermatopontin
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DPT mRNA
CTD
PMID:27935865
NCBI chr13:77,123,224...77,151,646
Ensembl chr13:77,123,115...77,151,639
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Dpy19l2
dpy-19 like 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DPY19L2 mRNA
CTD
PMID:27935865
NCBI chr 8:23,062,592...23,181,817
Ensembl chr 8:23,063,115...23,181,798
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Drd1
dopamine receptor D1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DRD1 mRNA
CTD
PMID:27935865
NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002
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Dusp10
dual specificity phosphatase 10
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of DUSP10 mRNA
CTD
PMID:20847119
NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
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Dusp26
dual specificity phosphatase 26
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of DUSP26 mRNA
CTD
PMID:27935865
NCBI chr16:61,041,784...61,049,319
Ensembl chr16:61,041,792...61,049,051
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Eddm3b
epididymal protein 3B
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of EDDM3B mRNA
CTD
PMID:27935865
NCBI chr15:24,343,992...24,346,759
Ensembl chr15:24,345,573...24,346,025
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Eef1a2
eukaryotic translation elongation factor 1 alpha 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EEF1A2 mRNA
CTD
PMID:27935865
NCBI chr 3:168,265,893...168,275,071
Ensembl chr 3:168,195,357...168,275,071
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Egf
epidermal growth factor
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EGF mRNA
CTD
PMID:27935865
NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
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Egflam
EGF-like, fibronectin type III and laminin G domains
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EGFLAM mRNA
CTD
PMID:27935865
NCBI chr 2:56,301,945...56,476,665
Ensembl chr 2:56,302,566...56,476,298
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Eif4e
eukaryotic translation initiation factor 4E
multiple interactions
ISO
[Metformin co-treated with Pioglitazone] results in decreased expression of EIF4E mRNA
CTD
PMID:32589349
NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683
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Eif4ebp1
eukaryotic translation initiation factor 4E binding protein 1
multiple interactions decreases phosphorylation increases expression
ISO
pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of EIF4EBP1 protein] pioglitazone results in decreased phosphorylation of EIF4EBP1 protein Pioglitazone results in increased expression of EIF4EBP1 mRNA
CTD
PMID:26643070 PMID:32589349
NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
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Eif4ebp2
eukaryotic translation initiation factor 4E binding protein 2
increases expression
ISO
Pioglitazone results in increased expression of EIF4EBP2 mRNA
CTD
PMID:32589349
NCBI chr20:29,379,444...29,400,110
Ensembl chr20:29,382,668...29,399,946
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Eif5a
eukaryotic translation initiation factor 5A
increases expression
ISO
pioglitazone results in increased expression of EIF5A mRNA
CTD
PMID:21347706
NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
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Elovl4
ELOVL fatty acid elongase 4
increases expression
ISO
Pioglitazone results in increased expression of ELOVL4 mRNA
CTD
PMID:30031879
NCBI chr 8:84,702,916...84,729,466
Ensembl chr 8:84,702,362...84,729,697
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Eno3
enolase 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ENO3 mRNA
CTD
PMID:27935865
NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921
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Epgn
epithelial mitogen
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of EPGN mRNA
CTD
PMID:27935865
NCBI chr14:17,076,774...17,084,806
Ensembl chr14:17,076,774...17,084,806
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Epha3
Eph receptor A3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EPHA3 mRNA
CTD
PMID:27935865
NCBI chr11:1,138,485...1,474,102
Ensembl chr11:1,140,985...1,473,900
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Epha5
EPH receptor A5
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EPHA5 mRNA
CTD
PMID:27935865
NCBI chr14:23,653,393...24,020,129
Ensembl chr14:23,653,393...24,017,317
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Epyc
epiphycan
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of EPYC mRNA
CTD
PMID:27935865
NCBI chr 7:32,436,620...32,474,326
Ensembl chr 7:32,436,620...32,474,135
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Erbin
erbb2 interacting protein
multiple interactions
ISO
pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ERBIN mRNA]
CTD
PMID:20847119
NCBI chr 2:34,926,962...35,028,440
Ensembl chr 2:34,928,863...35,027,852
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Ereg
epiregulin
increases expression
ISO
Pioglitazone results in increased expression of EREG mRNA
CTD
PMID:32816093
NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062
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F10
coagulation factor X
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of F10 mRNA
CTD
PMID:27935865
NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
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Fabp3
fatty acid binding protein 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FABP3 mRNA
CTD
PMID:27935865
NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718
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Fabp4
fatty acid binding protein 4
multiple interactions increases expression
ISO
[pioglitazone co-treated with Tretinoin] results in increased expression of FABP4 mRNA Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FABP4 mRNA] pioglitazone results in increased expression of FABP4 mRNA Pioglitazone results in increased expression of FABP4 mRNA
CTD
PMID:9543393 PMID:12927809 PMID:15273253 PMID:16573735 PMID:17290005 PMID:19048458 PMID:30031879 PMID:32473317 More...
NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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Fam13a
family with sequence similarity 13, member A
increases expression
ISO
Pioglitazone results in increased expression of FAM13A mRNA
CTD
PMID:30031879
NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860
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Fam171b
family with sequence similarity 171, member B
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FAM171B mRNA
CTD
PMID:27935865
NCBI chr 3:68,930,755...68,986,113
Ensembl chr 3:68,930,822...68,986,127
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Fam184b
family with sequence similarity 184, member B
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FAM184B mRNA
CTD
PMID:27935865
NCBI chr14:65,475,489...65,591,388
Ensembl chr14:65,475,489...65,591,388
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Fam210a
family with sequence similarity 210, member A
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of FAM210A mRNA
CTD
PMID:20847119
NCBI chr18:61,846,447...61,886,123
Ensembl chr18:61,852,907...61,886,171
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Fam240b
family with sequence similarity 240 member B
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of FAM240B mRNA
CTD
PMID:27935865
NCBI chr17:647,269...663,209
Ensembl chr17:657,303...663,206
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Fam47e
family with sequence similarity 47, member E
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FAM47E mRNA
CTD
PMID:27935865
NCBI chr14:15,485,537...15,521,599
Ensembl chr14:15,485,127...15,521,775
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Fat4
FAT atypical cadherin 4
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FAT4 mRNA
CTD
PMID:27935865
NCBI chr 2:121,927,266...122,056,700
Ensembl chr 2:121,927,942...122,056,707
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Fbln1
fibulin 1
increases expression
ISO
Pioglitazone results in increased expression of FBLN1 mRNA
CTD
PMID:30031879
NCBI chr 7:116,310,582...116,390,075
Ensembl chr 7:116,310,582...116,390,075
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Fbln7
fibulin 7
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FBLN7 mRNA
CTD
PMID:27935865
NCBI chr 3:116,111,581...116,145,839
Ensembl chr 3:116,111,677...116,147,983
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Fbxl16
F-box and leucine-rich repeat protein 16
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FBXL16 mRNA
CTD
PMID:27935865
NCBI chr10:14,829,453...14,841,739
Ensembl chr10:14,829,449...14,840,986
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Fbxo40
F-box protein 40
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FBXO40 mRNA
CTD
PMID:27935865
NCBI chr11:63,794,452...63,812,697
Ensembl chr11:63,794,624...63,812,697
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Fbxo43
F-box protein 43
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FBXO43 mRNA
CTD
PMID:27935865
NCBI chr 7:67,333,161...67,346,751
Ensembl chr 7:67,333,162...67,346,751
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Fcmr
Fc mu receptor
increases expression
ISO
Pioglitazone results in increased expression of FCMR mRNA
CTD
PMID:30031879
NCBI chr13:42,337,363...42,351,706
Ensembl chr13:42,337,414...42,351,653
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Fgf21
fibroblast growth factor 21
increases expression
ISO
pioglitazone results in increased expression of FGF21 mRNA
CTD
PMID:21720023
NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
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Fgf7
fibroblast growth factor 7
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FGF7 mRNA
CTD
PMID:27935865
NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
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Fgl1
fibrinogen-like 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FGL1 mRNA
CTD
PMID:27935865
NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093
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Fhl1
four and a half LIM domains 1
increases expression
ISO
Pioglitazone results in increased expression of FHL1 mRNA
CTD
PMID:30031879
NCBI chr X:134,555,399...134,614,930
Ensembl chr X:134,555,479...134,614,928
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Filip1
filamin A interacting protein 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FILIP1 mRNA
CTD
PMID:27935865
NCBI chr 8:80,761,283...80,956,556
Ensembl chr 8:80,764,604...80,922,549
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Fjx1
four-jointed box kinase 1
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of FJX1 mRNA
CTD
PMID:20847119
NCBI chr 3:88,774,220...88,776,321
Ensembl chr 3:88,774,220...88,776,321
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Fkbp1a
FKBP prolyl isomerase 1A
increases expression
ISO
Pioglitazone results in increased expression of FKBP1A mRNA
CTD
PMID:32589349
NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
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Fkbp8
FKBP prolyl isomerase 8
increases expression
ISO
Pioglitazone results in increased expression of FKBP8 mRNA
CTD
PMID:32589349
NCBI chr16:18,895,608...18,902,648
Ensembl chr16:18,893,576...18,902,612
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Flnc
filamin C
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FLNC mRNA
CTD
PMID:27935865
NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844
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Fndc5
fibronectin type III domain containing 5
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FNDC5 mRNA
CTD
PMID:27935865
NCBI chr 5:141,481,593...141,491,257
Ensembl chr 5:141,481,590...141,490,731
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Fos
Fos proto-oncogene, AP-1 transcription factor subunit
increases expression
EXP
pioglitazone results in increased expression of FOS mRNA
CTD
PMID:11687581
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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Fosb
FosB proto-oncogene, AP-1 transcription factor subunit
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of FOSB mRNA
CTD
PMID:27935865
NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
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Fosl1
FOS like 1, AP-1 transcription factor subunit
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of FOSL1 mRNA
CTD
PMID:27935865
NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
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Foxn4
forkhead box N4
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FOXN4 mRNA
CTD
PMID:27935865
NCBI chr12:42,336,706...42,359,932
Ensembl chr12:42,340,323...42,359,921
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Fpr1
formyl peptide receptor 1
decreases expression
ISO
Pioglitazone results in decreased expression of FPR1 mRNA
CTD
PMID:30031879
NCBI chr 1:58,745,019...58,756,776
Ensembl chr 1:58,747,246...58,756,559
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Frzb
frizzled-related protein
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FRZB mRNA
CTD
PMID:27935865
NCBI chr 3:65,332,274...65,365,208
Ensembl chr 3:65,332,277...65,365,208
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Fscn1
fascin actin-bundling protein 1
decreases expression
ISO
Pioglitazone results in decreased expression of FSCN1 mRNA
CTD
PMID:30031879
NCBI chr12:11,597,042...11,610,183
Ensembl chr12:11,597,048...11,610,211
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Fsd2
fibronectin type III and SPRY domain containing 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FSD2 mRNA
CTD
PMID:27935865
NCBI chr 1:135,484,002...135,522,517
Ensembl chr 1:135,489,266...135,522,472
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Fxyd1
FXYD domain-containing ion transport regulator 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of FXYD1 mRNA
CTD
PMID:27935865
NCBI chr 1:86,287,163...86,291,478
Ensembl chr 1:86,287,165...86,291,278
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Gabra3
gamma-aminobutyric acid type A receptor subunit alpha 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GABRA3 mRNA
CTD
PMID:27935865
NCBI chr X:150,244,745...150,501,566
Ensembl chr X:150,261,607...150,501,559
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Gabra4
gamma-aminobutyric acid type A receptor subunit alpha 4
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GABRA4 mRNA
CTD
PMID:27935865
NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844
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Galnt16
polypeptide N-acetylgalactosaminyltransferase 16
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GALNT16 mRNA
CTD
PMID:27935865
NCBI chr 6:100,168,943...100,250,718
Ensembl chr 6:100,170,306...100,250,705
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Galnt17
polypeptide N-acetylgalactosaminyltransferase 17
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of GALNT17 mRNA
CTD
PMID:27935865
NCBI chr12:25,323,230...25,781,897
Ensembl chr12:25,322,701...25,781,290
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Galnt9
polypeptide N-acetylgalactosaminyltransferase 9
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of GALNT9 mRNA
CTD
PMID:27935865
NCBI chr12:46,050,395...46,128,626
Ensembl chr12:46,050,413...46,128,578
G
Gdf15
growth differentiation factor 15
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of GDF15 mRNA
CTD
PMID:27935865
NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055
G
Gem
GTP binding protein overexpressed in skeletal muscle
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of GEM mRNA
CTD
PMID:20847119
NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
G
Gemin4
gem (nuclear organelle) associated protein 4
multiple interactions
ISO
[Pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of GEMIN4 mRNA
CTD
PMID:20847119
NCBI chr10:61,062,420...61,073,529
Ensembl chr10:61,066,425...61,073,431 Ensembl chr10:61,066,425...61,073,431
G
Gfra1
GDNF family receptor alpha 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GFRA1 mRNA
CTD
PMID:27935865
NCBI chr 1:257,315,682...257,552,004
Ensembl chr 1:257,321,742...257,551,473
G
Gh1
growth hormone 1
increases expression
ISO
Pioglitazone results in increased expression of GH1 mRNA
CTD
PMID:30031879
NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
G
Gimap4
GTPase, IMAP family member 4
decreases expression
ISO
Pioglitazone results in decreased expression of GIMAP4 mRNA
CTD
PMID:30031879
NCBI chr 4:77,636,401...77,643,315
Ensembl chr 4:77,636,401...77,643,306
G
Gldn
gliomedin
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GLDN mRNA
CTD
PMID:27935865
NCBI chr 8:54,679,015...54,723,198
Ensembl chr 8:54,679,119...54,723,196
G
Gmnc
geminin coiled-coil domain containing
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GMNC mRNA
CTD
PMID:27935865
NCBI chr11:73,836,255...73,847,698
Ensembl chr11:73,814,533...73,847,328
G
Gnat3
G protein subunit alpha transducin 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GNAT3 mRNA
CTD
PMID:27935865
NCBI chr 4:17,162,500...17,212,283
Ensembl chr 4:17,162,490...17,212,283
G
Got1
glutamic-oxaloacetic transaminase 1
multiple interactions
EXP
pioglitazone inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of GOT1 protein]
CTD
PMID:15318101
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
G
Got1l1
glutamic-oxaloacetic transaminase 1-like 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GOT1L1 mRNA
CTD
PMID:27935865
NCBI chr16:64,860,308...64,873,656
Ensembl chr16:64,860,704...64,866,162
G
Gp2
glycoprotein 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GP2 mRNA
CTD
PMID:27935865
NCBI chr 1:173,797,057...173,812,619
Ensembl chr 1:173,797,057...173,812,619
G
Gpihbp1
glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GPIHBP1 mRNA
CTD
PMID:27935865
NCBI chr 7:107,285,584...107,288,702
Ensembl chr 7:107,285,654...107,288,702
G
Gpm6a
glycoprotein m6a
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GPM6A mRNA
CTD
PMID:27935865
NCBI chr16:36,641,282...36,973,377
Ensembl chr16:36,641,284...36,973,475
G
Gpr183
G protein-coupled receptor 183
decreases expression
ISO
Pioglitazone results in decreased expression of GPR183 mRNA
CTD
PMID:30031879
NCBI chr15:99,037,764...99,050,550
Ensembl chr15:99,036,367...99,050,559
G
Gpr84
G protein-coupled receptor 84
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of GPR84 mRNA
CTD
PMID:27935865
NCBI chr 7:134,443,904...134,446,173
Ensembl chr 7:134,443,936...134,446,178
G
Gprasp2
G protein-coupled receptor associated sorting protein 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GPRASP2 mRNA
CTD
PMID:27935865
NCBI chr X:98,817,668...98,823,814
Ensembl chr X:98,817,593...98,824,402
G
Gpt
glutamic--pyruvic transaminase
multiple interactions
EXP
pioglitazone inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of GPT protein]; pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased activity of GPT protein]
CTD
PMID:15318101 PMID:27350165
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
G
Gpx3
glutathione peroxidase 3
increases expression
ISO
Pioglitazone results in increased expression of GPX3 mRNA
CTD
PMID:30031879
NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
G
Grm4
glutamate metabotropic receptor 4
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of GRM4 mRNA
CTD
PMID:27935865
NCBI chr20:5,484,172...5,572,821
Ensembl chr20:5,481,124...5,572,821
G
Gsk3b
glycogen synthase kinase 3 beta
increases expression
ISO
Pioglitazone results in increased expression of GSK3B mRNA
CTD
PMID:32589349
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
G
Gsta2
glutathione S-transferase alpha 2
multiple interactions
EXP
[pioglitazone co-treated with alitretinoin] results in increased expression of GSTA2 protein
CTD
PMID:15150131
NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
G
Gstp1
glutathione S-transferase pi 1
multiple interactions
EXP
pioglitazone inhibits the reaction [Diethylnitrosamine results in increased expression of GSTP1 protein]
CTD
PMID:15526359
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
G
Gstt1
glutathione S-transferase theta 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GSTT1 mRNA
CTD
PMID:27935865
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
G
Gucy1a1
guanylate cyclase 1 soluble subunit alpha 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of GUCY1A1 mRNA
CTD
PMID:27935865
NCBI chr 2:167,418,615...167,482,293
Ensembl chr 2:167,418,640...167,481,671
G
Hbb
hemoglobin subunit beta
multiple interactions
EXP
Pioglitazone inhibits the reaction [Fructose promotes the reaction [Glucose binds to HBB protein]]
CTD
PMID:25679220
NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
G
Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HECW1 mRNA
CTD
PMID:27935865
NCBI chr17:50,671,239...51,084,536
Ensembl chr17:50,670,954...51,080,720
G
Hhatl
hedgehog acyltransferase-like
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HHATL mRNA
CTD
PMID:27935865
NCBI chr 8:121,447,001...121,454,070
Ensembl chr 8:121,447,002...121,454,001
G
Hhip
Hedgehog-interacting protein
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HHIP mRNA
CTD
PMID:27935865
NCBI chr19:27,863,684...27,952,528
Ensembl chr19:27,863,213...27,952,528
G
Hif1a
hypoxia inducible factor 1 subunit alpha
decreases expression multiple interactions
ISO
Pioglitazone results in decreased expression of HIF1A mRNA [Metformin co-treated with Pioglitazone] results in decreased expression of HIF1A mRNA
CTD
PMID:32589349
NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
G
Hif3a
hypoxia inducible factor 3 subunit alpha
decreases expression
EXP
pioglitazone results in decreased expression of HIF3A mRNA
CTD
PMID:22456468
NCBI chr 1:77,718,110...77,750,448
Ensembl chr 1:77,722,471...77,749,758
G
Hilpda
hypoxia inducible lipid droplet-associated
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of HILPDA mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of HILPDA mRNA]
CTD
PMID:20847119
NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557
G
Hjv
hemojuvelin BMP co-receptor
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of HJV mRNA
CTD
PMID:27935865
NCBI chr 2:184,065,944...184,069,851
Ensembl chr 2:184,065,970...184,069,850
G
Hmgcr
3-hydroxy-3-methylglutaryl-CoA reductase
increases expression decreases expression
ISO
pioglitazone results in increased expression of HMGCR mRNA pioglitazone results in decreased expression of HMGCR mRNA
CTD
PMID:12044893 PMID:20503262
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
G
Hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1
increases expression
ISO
pioglitazone results in increased expression of HMGCS1 mRNA
CTD
PMID:12044893
NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
G
Hmox1
heme oxygenase 1
increases expression multiple interactions
EXP ISO
pioglitazone results in increased expression of HMOX1 mRNA [pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of HMOX1 mRNA Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of HMOX1 mRNA]; Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 mRNA]
CTD
PMID:16597547 PMID:28263783 PMID:30965670
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
G
Hnrnpdl
heterogeneous nuclear ribonucleoprotein D-like
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of HNRNPDL mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of HNRNPDL mRNA]
CTD
PMID:20847119
NCBI chr14:9,557,430...9,563,659
Ensembl chr14:9,557,425...9,562,506
G
Hpgd
15-hydroxyprostaglandin dehydrogenase
multiple interactions
ISO
[pioglitazone co-treated with NAD] binds to HPGD protein
CTD
PMID:25526675
NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
G
Hpse2
heparanase 2 (inactive)
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HPSE2 mRNA
CTD
PMID:27935865
NCBI chr 1:241,582,904...242,284,348
Ensembl chr 1:241,583,187...242,246,118
G
Hrc
histidine rich calcium binding protein
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HRC mRNA
CTD
PMID:27935865
NCBI chr 1:95,813,262...95,816,987
Ensembl chr 1:95,813,253...95,816,984
G
Hsd3b2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
decreases expression decreases activity
ISO
pioglitazone results in decreased expression of HSD3B2 mRNA pioglitazone results in decreased activity of HSD3B2 protein
CTD
PMID:15072549 PMID:17138841
NCBI chr 2:186,095,897...186,105,354
Ensembl chr 2:186,095,897...186,101,852
G
Hspa12b
heat shock protein family A (Hsp70) member 12B
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HSPA12B mRNA
CTD
PMID:27935865
NCBI chr 3:118,346,372...118,364,374
Ensembl chr 3:118,346,354...118,364,737
G
Hspa1l
heat shock protein family A (Hsp70) member 1 like
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of HSPA1L mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of HSPA1L mRNA]
CTD
PMID:20847119
NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
G
Hspb7
heat shock protein family B (small) member 7
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of HSPB7 mRNA
CTD
PMID:27935865
NCBI chr 5:153,727,782...153,731,268
Ensembl chr 5:153,727,588...153,731,266
G
Htr2b
5-hydroxytryptamine receptor 2B
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of HTR2B mRNA
CTD
PMID:27935865
NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108
G
Icam1
intercellular adhesion molecule 1
multiple interactions
ISO
pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of ICAM1 protein]
CTD
PMID:17015710
NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
G
Id2
inhibitor of DNA binding 2
multiple interactions
ISO
[Pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ID2 mRNA; Pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ID2 mRNA]
CTD
PMID:20847119
NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
G
Ifng
interferon gamma
multiple interactions
ISO
pioglitazone inhibits the reaction [[IFNG protein co-treated with IL1B protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]; pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of and results in increased activity of BACE1 protein]; pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]
CTD
PMID:14586007
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
G
Igf1
insulin-like growth factor 1
decreases expression multiple interactions
ISO
Pioglitazone results in decreased expression of IGF1 mRNA [Metformin co-treated with Pioglitazone] results in decreased expression of IGF1 mRNA
CTD
PMID:32589349
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
G
Igsf10
immunoglobulin superfamily, member 10
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of IGSF10 mRNA
CTD
PMID:27935865
NCBI chr 2:143,575,710...143,605,044
Ensembl chr 2:143,576,070...143,604,773
G
Ikbkb
inhibitor of nuclear factor kappa B kinase subunit beta
decreases expression
ISO
Pioglitazone results in decreased expression of IKBKB mRNA
CTD
PMID:32589349
NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
G
Il10
interleukin 10
multiple interactions increases expression
EXP ISO
Pioglitazone inhibits the reaction [propionic acid results in decreased expression of IL10 protein] Pioglitazone results in increased expression of IL10 protein
CTD
PMID:27918843 PMID:31348919
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
G
Il13
interleukin 13
multiple interactions
ISO
pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL13 protein]
CTD
PMID:17015710
NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
G
Il18
interleukin 18
multiple interactions
EXP
pioglitazone inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA]
CTD
PMID:18660453
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
G
Il1a
interleukin 1 alpha
increases expression
ISO
Pioglitazone results in increased expression of IL1A mRNA
CTD
PMID:32816093
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
G
Il1b
interleukin 1 beta
multiple interactions affects expression increases expression
ISO EXP
Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Pioglitazone inhibits the reaction [[IFNG protein co-treated with IL1B protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein] pioglitazone affects the expression of IL1B mRNA [pioglitazone co-treated with Lipopolysaccharides] results in increased expression of IL1B mRNA Pioglitazone results in increased expression of IL1B mRNA [naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of IL1B mRNA]; Fenofibrate promotes the reaction [Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]]; Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]; Pioglitazone inhibits the reaction [Fructose results in increased secretion of IL1B protein]; Pioglitazone inhibits the reaction [Quinolinic Acid results in increased expression of IL1B mRNA]; Pioglitazone promotes the reaction [Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of IL1B protein]]
CTD
PMID:14586007 PMID:25679220 PMID:28138970 PMID:30031879 PMID:30130594 PMID:32613381 PMID:32816093 PMID:36988379 More...
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
G
Il23a
interleukin 23 subunit alpha
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of IL23A mRNA
CTD
PMID:27935865
NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
G
Il24
interleukin 24
multiple interactions increases expression
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of IL24 mRNA Pioglitazone results in increased expression of IL24 mRNA
CTD
PMID:27935865 PMID:32816093
NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
G
Il4
interleukin 4
multiple interactions
ISO
pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL4 protein]
CTD
PMID:17015710
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
G
Il5
interleukin 5
multiple interactions
ISO
pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL5 protein]
CTD
PMID:17015710
NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213
G
Il6
interleukin 6
multiple interactions affects expression increases expression
ISO EXP
[Pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of IL6 mRNA; [Sodium Glutamate co-treated with Pioglitazone] results in decreased expression of IL6 protein; Pioglitazone inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of IL6 mRNA]; Pioglitazone inhibits the reaction [Sodium Glutamate results in increased expression of IL6 mRNA]; Pioglitazone promotes the reaction [Plant Extracts results in increased expression of IL6 protein] pioglitazone affects the expression of IL6 protein [naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of IL6 mRNA]; Pioglitazone inhibits the reaction [propionic acid results in increased expression of IL6 protein]; Pioglitazone inhibits the reaction [Quinolinic Acid results in increased expression of IL6 mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of IL6 protein] Pioglitazone results in increased expression of IL6 protein
CTD
PMID:18513333 PMID:27918843 PMID:28263783 PMID:28744220 PMID:29233026 PMID:30130594 PMID:31348919 PMID:37044004 More...
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
G
Ilk
integrin-linked kinase
decreases expression
ISO
Pioglitazone results in decreased expression of ILK mRNA
CTD
PMID:32589349
NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140
G
Inmt
indolethylamine N-methyltransferase
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of INMT mRNA
CTD
PMID:27935865
NCBI chr 4:84,318,197...84,322,493
Ensembl chr 4:84,318,197...84,322,493
G
Ins1
insulin 1
multiple interactions affects expression decreases secretion
EXP ISO
Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of INS1 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of INS1 protein] Pioglitazone promotes the reaction [INS1 protein results in increased uptake of Glucose] Pioglitazone affects the expression of INS1 protein Pioglitazone promotes the reaction [[Glucose co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of ADIPOQ protein] Pioglitazone results in decreased secretion of INS1 protein
CTD
PMID:14532171 PMID:19208898 PMID:27350165 PMID:28242381 PMID:29233026 PMID:32407875 PMID:37044004 More...
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
G
Ins2
insulin 2
multiple interactions
ISO
2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]]; [Dexamethasone co-treated with INS protein co-treated with Pioglitazone] results in increased expression of PPARG protein; octocrylene inhibits the reaction [Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of and results in increased secretion of ADIPOQ protein]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]; T 0070907 inhibits the reaction [Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased secretion of ADIPOQ protein]] [Dexamethasone co-treated with INS protein co-treated with Pioglitazone] results in increased expression of PPARG protein; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of BGLAP mRNA]; Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of FABP4 mRNA]; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]; Pioglitazone promotes the reaction [[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of FABP4 mRNA]
CTD
PMID:15273253 PMID:17290005 PMID:31016361 PMID:32473317 PMID:32613381 PMID:34864131 More...
NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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Insyn2b
inhibitory synaptic factor family member 2B
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of INSYN2B mRNA
CTD
PMID:27935865
NCBI chr10:18,916,721...19,023,859
Ensembl chr10:19,003,131...19,022,139
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Iqch
IQ motif containing H
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of IQCH mRNA
CTD
PMID:27935865
NCBI chr 8:63,889,816...64,083,248
Ensembl chr 8:63,892,370...64,083,223
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Irag1
inositol 1,4,5-triphosphate receptor associated 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of IRAG1 mRNA
CTD
PMID:27935865
NCBI chr 1:164,981,716...165,094,232
Ensembl chr 1:164,981,716...165,094,176
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Isl1
ISL LIM homeobox 1
increases expression
ISO
Pioglitazone results in increased expression of ISL1 mRNA
CTD
PMID:30031879
NCBI chr 2:48,079,412...48,090,704
Ensembl chr 2:48,080,522...48,095,584
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Ism2
isthmin 2
increases expression
ISO
Pioglitazone results in increased expression of ISM2 mRNA
CTD
PMID:30031879
NCBI chr 6:106,921,213...106,944,291
Ensembl chr 6:106,926,175...106,944,514
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Itga8
integrin subunit alpha 8
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ITGA8 mRNA
CTD
PMID:27935865
NCBI chr17:75,304,004...75,501,510
Ensembl chr17:75,304,008...75,501,510
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Itgav
integrin subunit alpha V
multiple interactions
ISO
pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ITGAV mRNA]
CTD
PMID:20847119
NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639
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Itgb1bp2
integrin subunit beta 1 binding protein 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ITGB1BP2 mRNA
CTD
PMID:27935865
NCBI chr X:66,572,537...66,577,174
Ensembl chr X:66,572,537...66,577,174
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Itih2
inter-alpha-trypsin inhibitor heavy chain 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ITIH2 mRNA
CTD
PMID:27935865
NCBI chr17:68,375,574...68,411,849
Ensembl chr17:68,375,567...68,411,841
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Itln1
intelectin 1
increases expression
ISO
pioglitazone results in increased expression of ITLN1 protein
CTD
PMID:23555749
NCBI chr13:83,932,234...83,958,243
Ensembl chr13:83,948,124...83,958,227
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Jchain
joining chain of multimeric IgA and IgM
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of JCHAIN mRNA
CTD
PMID:27935865
NCBI chr14:19,538,927...19,547,023
Ensembl chr14:19,538,952...19,546,298
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Jph2
junctophilin 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of JPH2 mRNA
CTD
PMID:27935865
NCBI chr 3:151,994,768...152,058,941
Ensembl chr 3:151,994,778...152,058,904
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Kank4
KN motif and ankyrin repeat domains 4
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KANK4 mRNA
CTD
PMID:27935865
NCBI chr 5:113,401,491...113,465,526
Ensembl chr 5:113,402,468...113,465,555
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Kcnb1
potassium voltage-gated channel subfamily B member 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KCNB1 mRNA
CTD
PMID:27935865
NCBI chr 3:155,820,255...155,913,383
Ensembl chr 3:155,822,963...155,916,194
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Kcnc4
potassium voltage-gated channel subfamily C member 4
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KCNC4 mRNA
CTD
PMID:27935865
NCBI chr 2:195,063,967...195,100,244
Ensembl chr 2:195,071,769...195,099,233
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Kcnd3
potassium voltage-gated channel subfamily D member 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KCND3 mRNA
CTD
PMID:27935865
NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345
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Kcnj11
potassium inwardly-rectifying channel, subfamily J, member 11
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KCNJ11 mRNA
CTD
PMID:27935865
NCBI chr 1:96,591,048...96,594,574
Ensembl chr 1:96,591,049...96,594,082
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Kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KCNJ13 mRNA
CTD
PMID:27935865
NCBI chr 9:88,063,003...88,071,112
Ensembl chr 9:88,063,003...88,071,112
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Klf2
KLF transcription factor 2
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of KLF2 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of KLF2 mRNA]
CTD
PMID:20847119
NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944
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Klf5
KLF transcription factor 5
multiple interactions
EXP
Pioglitazone inhibits the reaction [AGT protein results in increased expression of KLF5 mRNA]; Pioglitazone inhibits the reaction [AGT protein results in increased expression of KLF5 protein]
CTD
PMID:25874449
NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
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Klhl13
kelch-like family member 13
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KLHL13 mRNA
CTD
PMID:27935865
NCBI chr X:113,942,309...114,107,299
Ensembl chr X:113,942,309...114,107,321
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Klhl31
kelch-like family member 31
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KLHL31 mRNA
CTD
PMID:27935865
NCBI chr 8:78,515,514...78,538,873
Ensembl chr 8:78,515,514...78,538,873
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Klhl40
kelch-like family member 40
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KLHL40 mRNA
CTD
PMID:27935865
NCBI chr 8:121,441,285...121,446,801
Ensembl chr 8:121,441,287...121,446,800
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Klhl41
kelch-like family member 41
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KLHL41 mRNA
CTD
PMID:27935865
NCBI chr 3:54,434,291...54,447,415
Ensembl chr 3:54,434,234...54,449,222
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Klk6
kallikrein related-peptidase 6
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of KLK6 mRNA
CTD
PMID:27935865
NCBI chr 1:94,278,863...94,286,136
Ensembl chr 1:94,280,340...94,286,121
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Krt16
keratin 16
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of KRT16 mRNA
CTD
PMID:27935865
NCBI chr10:85,168,357...85,171,816
Ensembl chr10:85,066,802...85,171,799
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Krt20
keratin 20
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of KRT20 mRNA
CTD
PMID:27935865
NCBI chr10:84,384,790...84,394,125
Ensembl chr10:84,384,802...84,394,107
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Krt84
keratin 84
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of KRT84 mRNA
CTD
PMID:27935865
NCBI chr 7:132,649,064...132,656,885
Ensembl chr 7:132,649,061...132,656,874
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Krt90
keratin 90
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in increased expression of KRT90 mRNA
CTD
PMID:27935865
NCBI chr 7:132,677,994...132,686,634
Ensembl chr 7:132,677,751...132,686,759
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Ky
kyphoscoliosis peptidase
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of KY mRNA
CTD
PMID:27935865
NCBI chr 8:103,086,959...103,126,305
Ensembl chr 8:103,086,630...103,126,024
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Lama2
laminin subunit alpha 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LAMA2 mRNA
CTD
PMID:27935865
NCBI chr 1:17,672,675...18,320,641
Ensembl chr 1:17,672,536...18,320,530
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Larp6
La ribonucleoprotein 6, translational regulator
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LARP6 mRNA
CTD
PMID:27935865
NCBI chr 8:61,183,744...61,205,548
Ensembl chr 8:61,184,116...61,205,535
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Lce1f
late cornified envelope 1F
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of LCE1F mRNA
CTD
PMID:27935865
NCBI chr 2:178,305,786...178,307,372
Ensembl chr 2:178,305,786...178,307,372
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Ldlr
low density lipoprotein receptor
increases expression multiple interactions
ISO
pioglitazone results in increased expression of LDLR protein [pioglitazone co-treated with U 0126] affects the localization of LDLR protein
CTD
PMID:22593575
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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Lep
leptin
increases expression
EXP
pioglitazone results in increased expression of LEP protein
CTD
PMID:15655531
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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Lepr
leptin receptor
increases response to substance multiple interactions
EXP ISO
LEPR gene mutant form results in increased susceptibility to Pioglitazone Pioglitazone inhibits the reaction [LEPR protein affects the expression of OGG1 protein]; Pioglitazone inhibits the reaction [LEPR protein affects the expression of XRCC1 protein]
CTD
PMID:29743445 PMID:35472412
NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
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Lgi1
leucine-rich, glioma inactivated 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LGI1 mRNA
CTD
PMID:27935865
NCBI chr 1:236,043,269...236,084,617
Ensembl chr 1:236,042,954...236,084,616
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Lhfpl4
LHFPL tetraspan subfamily member 4
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LHFPL4 mRNA
CTD
PMID:27935865
NCBI chr 4:146,317,110...146,340,073
Ensembl chr 4:146,313,541...146,340,463
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Lipc
lipase C, hepatic type
increases expression
ISO
pioglitazone results in increased expression of LIPC mRNA
CTD
PMID:20503262
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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Lipf
lipase F, gastric type
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LIPF mRNA
CTD
PMID:27935865
NCBI chr 1:231,493,498...231,511,845
Ensembl chr 1:231,493,498...231,511,845
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Lipn
lipase, family member N
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of LIPN mRNA
CTD
PMID:27935865
NCBI chr 1:231,584,950...231,603,456
Ensembl chr 1:231,584,956...231,603,468
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Litaf
lipopolysaccharide-induced TNF factor
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of LITAF mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of LITAF mRNA]
CTD
PMID:20847119
NCBI chr10:4,656,308...4,692,981
Ensembl chr10:4,625,552...4,692,763
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Lman1l
lectin, mannose-binding, 1 like
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LMAN1L mRNA
CTD
PMID:27935865
NCBI chr 8:58,010,839...58,029,599
Ensembl chr 8:58,010,839...58,023,681
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Lmod3
leiomodin 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LMOD3 mRNA
CTD
PMID:27935865
NCBI chr 4:129,843,964...129,858,684
Ensembl chr 4:129,843,970...129,858,244
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LOC120098377
U1 spliceosomal RNA
decreases expression
ISO
Pioglitazone results in decreased expression of RNVU1-7 mRNA
CTD
PMID:30031879
NCBI chr18:79,901,335...79,901,477
Ensembl chr18:79,901,335...79,901,477 Ensembl chr18:79,901,335...79,901,477
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LOC120100584
small proline-rich protein 2I-like
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in increased expression of SPRR2H mRNA
CTD
PMID:27935865
NCBI chr 2:177,815,964...177,816,236
Ensembl chr 2:177,815,964...177,816,236
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Lrrc39
leucine rich repeat containing 39
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LRRC39 mRNA
CTD
PMID:27935865
NCBI chr 2:204,516,122...204,535,463
Ensembl chr 2:204,516,123...204,535,463
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Lrrc3b
leucine rich repeat containing 3B
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LRRC3B mRNA
CTD
PMID:27935865
NCBI chr15:9,973,580...10,050,891
Ensembl chr15:9,969,983...10,051,066
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Lrrn1
leucine rich repeat neuronal 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LRRN1 mRNA
CTD
PMID:27935865
NCBI chr 4:140,476,752...140,520,210
Ensembl chr 4:140,476,324...140,518,620
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Lrrn3
leucine rich repeat neuronal 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of LRRN3 mRNA
CTD
PMID:27935865
NCBI chr 6:58,489,060...58,520,322
Ensembl chr 6:58,489,010...58,520,330
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Magix
MAGI family member, X-linked
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MAGIX mRNA
CTD
PMID:27935865
NCBI chr X:14,824,114...14,832,466
Ensembl chr X:14,824,188...14,831,045
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Maob
monoamine oxidase B
multiple interactions
ISO
pioglitazone binds to and results in decreased activity of MAOB protein
CTD
PMID:22282722
NCBI chr X:5,907,327...6,010,996
Ensembl chr X:5,907,266...6,011,003
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Mapk1
mitogen activated protein kinase 1
multiple interactions decreases phosphorylation
EXP ISO
pioglitazone inhibits the reaction [Streptozocin results in increased expression of MAPK1 mRNA]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of MAPK1 protein]; pioglitazone results in increased phosphorylation of and results in increased activity of MAPK1 protein [PDGFB protein binds to PDGFB protein] inhibits the reaction [pioglitazone results in decreased phosphorylation of MAPK1 protein]
CTD
PMID:11687581 PMID:17063547 PMID:26643070
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
multiple interactions decreases phosphorylation
EXP ISO
pioglitazone results in increased phosphorylation of and results in increased activity of MAPK3 protein pioglitazone results in decreased phosphorylation of MAPK3 protein [PDGFB protein binds to PDGFB protein] inhibits the reaction [pioglitazone results in decreased phosphorylation of MAPK3 protein]
CTD
PMID:11687581 PMID:26643070
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Mb
myoglobin
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MB mRNA
CTD
PMID:27935865
NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383
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Mb21d2
Mab-21 domain containing 2
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of MB21D2 mRNA
CTD
PMID:20847119
NCBI chr11:71,825,748...71,924,770
Ensembl chr11:71,825,748...71,924,769
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Mcemp1
mast cell-expressed membrane protein 1
increases expression
ISO
Pioglitazone results in increased expression of MCEMP1 mRNA
CTD
PMID:30031879
NCBI chr12:1,721,781...1,727,350
Ensembl chr12:1,718,730...1,725,986
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Mcidas
multiciliate differentiation and DNA synthesis associated cell cycle protein
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MCIDAS mRNA
CTD
PMID:27935865
NCBI chr 2:44,636,820...44,644,551
Ensembl chr 2:44,636,856...44,642,601
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Mef2c
myocyte enhancer factor 2C
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MEF2C mRNA
CTD
PMID:27935865
NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880
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Met
MET proto-oncogene, receptor tyrosine kinase
increases expression
ISO
Pioglitazone results in increased expression of MET mRNA
CTD
PMID:32816093
NCBI chr 4:45,790,456...45,898,139
Ensembl chr 4:45,790,791...45,897,876
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Mettl21ep
methyltransferase like 21E, pseudogene
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of METTL21E mRNA
CTD
PMID:27935865
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Mfap4
microfibril associated protein 4
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MFAP4 mRNA
CTD
PMID:27935865
NCBI chr10:46,167,158...46,170,176
Ensembl chr10:46,167,217...46,170,155
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Mgam
maltase-glucoamylase
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in increased expression of MGAM mRNA
CTD
PMID:27935865
NCBI chr 4:69,441,626...69,602,068
Ensembl chr 4:69,446,150...69,692,715
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Mir133b
microRNA 133b
multiple interactions
ISO
[Pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of MIR133B mRNA
CTD
PMID:28263783
NCBI chr 9:23,098,134...23,098,217
Ensembl chr 9:23,098,134...23,098,217
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Mir206
microRNA 206
multiple interactions
ISO
[Pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of MIR206 mRNA
CTD
PMID:28263783
NCBI chr 9:23,094,249...23,094,332
Ensembl chr 9:23,094,249...23,094,332
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Mlip
muscular LMNA-interacting protein
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MLIP mRNA
CTD
PMID:27935865
NCBI chr 8:77,935,087...78,204,725
Ensembl chr 8:77,935,079...78,204,254
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Mme
membrane metallo-endopeptidase
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MME mRNA
CTD
PMID:27935865
NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792
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Mmp12
matrix metallopeptidase 12
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of MMP12 mRNA
CTD
PMID:27935865
NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611
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Mmp13
matrix metallopeptidase 13
multiple interactions
EXP
pioglitazone affects the reaction [Carbon Tetrachloride results in increased cleavage of MMP13 protein]
CTD
PMID:16484506
NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239
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Mmp7
matrix metallopeptidase 7
multiple interactions decreases expression
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of MMP7 mRNA Pioglitazone results in decreased expression of MMP7 mRNA
CTD
PMID:27935865 PMID:30031879
NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
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Mmp8
matrix metallopeptidase 8
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of MMP8 mRNA
CTD
PMID:27935865
NCBI chr 8:4,724,009...4,733,864
Ensembl chr 8:4,724,029...4,733,520
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Mmp9
matrix metallopeptidase 9
multiple interactions decreases secretion decreases expression
ISO
2-chloro-5-nitrobenzanilide inhibits the reaction [pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein]]; pioglitazone inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MMP9 protein] pioglitazone results in decreased secretion of MMP9 protein Pioglitazone results in decreased expression of MMP9 mRNA
CTD
PMID:16860414 PMID:17055343 PMID:30031879
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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Ms4a7
membrane spanning 4-domains A7
increases expression
ISO
Pioglitazone results in increased expression of MS4A7 mRNA
CTD
PMID:30031879
NCBI chr 1:207,969,117...207,984,743
Ensembl chr 1:207,968,761...207,983,260
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Mstn
myostatin
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MSTN mRNA
CTD
PMID:27935865
NCBI chr 9:48,452,533...48,458,933
Ensembl chr 9:48,452,533...48,458,933
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Mtarc1
mitochondrial amidoxime reducing component 1
increases expression
ISO
Pioglitazone results in increased expression of MTARC1 mRNA
CTD
PMID:30031879
NCBI chr13:96,324,377...96,362,677
Ensembl chr13:96,339,757...96,397,796
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Mtor
mechanistic target of rapamycin kinase
multiple interactions
ISO
[Metformin co-treated with Pioglitazone] results in decreased expression of MTOR mRNA
CTD
PMID:32589349
NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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Muc1
mucin 1, cell surface associated
decreases expression
ISO
Pioglitazone results in decreased expression of MUC1 mRNA
CTD
PMID:30031879
NCBI chr 2:174,635,989...174,640,738
Ensembl chr 2:174,635,995...174,640,733
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Muc5b
mucin 5B, oligomeric mucus/gel-forming
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MUC5B mRNA
CTD
PMID:27935865
NCBI chr 1:196,916,861...196,948,830
Ensembl chr 1:196,916,825...196,949,250
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Mucl3
mucin like 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of MUCL3 mRNA
CTD
PMID:27935865
NCBI chr20:3,100,652...3,108,569
Ensembl chr20:3,100,679...3,108,569
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Mxd1
max dimerization protein 1
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of MXD1 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of MXD1 mRNA]
CTD
PMID:20847119
NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751
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Mybpc1
myosin binding protein C1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYBPC1 mRNA
CTD
PMID:27935865
NCBI chr 7:22,930,350...23,015,981
Ensembl chr 7:22,930,350...23,015,957
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Myf6
myogenic factor 6
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYF6 mRNA
CTD
PMID:27935865
NCBI chr 7:42,813,008...42,814,852
Ensembl chr 7:42,812,792...42,814,852
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Myh1
myosin heavy chain 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYH1 mRNA
CTD
PMID:27935865
NCBI chr10:51,885,913...51,909,699
Ensembl chr10:51,885,913...51,946,295
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Myh11
myosin heavy chain 11
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYH11 mRNA
CTD
PMID:27935865
NCBI chr10:743,364...838,459
Ensembl chr10:743,685...838,459
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Myh13
myosin heavy chain 13
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYH13 mRNA
CTD
PMID:27935865
NCBI chr10:52,012,779...52,068,960
Ensembl chr10:52,009,425...52,068,951
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Myh2
myosin heavy chain 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYH2 mRNA
CTD
PMID:27935865
NCBI chr10:51,856,738...51,883,236
Ensembl chr10:51,856,738...51,883,236
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Myh4
myosin heavy chain 4
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of MYH4 mRNA
CTD
PMID:27935865
NCBI chr10:51,923,149...51,946,297
Ensembl chr10:51,885,913...51,946,295
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Myl1
myosin, light chain 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYL1 mRNA
CTD
PMID:27935865
NCBI chr 9:68,437,514...68,458,256
Ensembl chr 9:68,437,517...68,458,261
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Myl11
myosin light chain 11
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of MYLPF mRNA
CTD
PMID:27935865
NCBI chr 1:181,829,703...181,832,546
Ensembl chr 1:181,829,743...181,832,545
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Myl9
myosin light chain 9
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYL9 mRNA
CTD
PMID:27935865
NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
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Mylk
myosin light chain kinase
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYLK mRNA
CTD
PMID:27935865
NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
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Myo18b
myosin XVIIIb
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYO18B mRNA
CTD
PMID:27935865
NCBI chr12:43,747,003...43,953,694
Ensembl chr12:43,747,010...43,953,695
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Myo1c
myosin 1C
increases expression
ISO
Pioglitazone results in increased expression of MYO1C mRNA
CTD
PMID:32589349
NCBI chr10:60,498,372...60,520,752
Ensembl chr10:60,498,280...60,520,752
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Myom1
myomesin 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOM1 mRNA
CTD
PMID:27935865
NCBI chr 9:110,916,156...111,039,344
Ensembl chr 9:110,915,943...111,039,344
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Myom2
myomesin 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOM2 mRNA
CTD
PMID:27935865
NCBI chr16:74,520,148...74,592,658
Ensembl chr16:74,520,157...74,592,772
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Myom3
myomesin 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOM3 mRNA
CTD
PMID:27935865
NCBI chr 5:147,992,737...148,043,282
Ensembl chr 5:147,992,737...148,043,274
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Myot
myotilin
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOT mRNA
CTD
PMID:27935865
NCBI chr18:36,705,244...36,724,849
Ensembl chr18:36,705,314...36,724,841
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Myoz1
myozenin 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOZ1 mRNA
CTD
PMID:27935865
NCBI chr15:3,644,333...3,651,584
Ensembl chr15:3,644,368...3,652,884
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Myoz3
myozenin 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYOZ3 mRNA
CTD
PMID:27935865
NCBI chr18:54,026,133...54,046,151
Ensembl chr18:54,026,152...54,102,126
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Mypn
myopalladin
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MYPN mRNA
CTD
PMID:27935865
NCBI chr20:25,429,898...25,522,443
Ensembl chr20:25,436,843...25,522,443
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Mzb1
marginal zone B and B1 cell-specific protein
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of MZB1 mRNA
CTD
PMID:27935865
NCBI chr18:27,238,999...27,241,060
Ensembl chr18:27,239,001...27,241,094
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Naalad2
N-acetylated alpha-linked acidic dipeptidase 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NAALAD2 mRNA
CTD
PMID:27935865
NCBI chr 8:15,406,119...15,479,714
Ensembl chr 8:15,407,043...15,479,714
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Ndrg1
N-myc downstream regulated 1
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of NDRG1 mRNA
CTD
PMID:20847119
NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
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Neb
nebulin
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NEB mRNA
CTD
PMID:27935865
NCBI chr 3:36,613,677...36,811,618
Ensembl chr 3:36,613,716...36,811,574
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Negr1
neuronal growth regulator 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NEGR1 mRNA
CTD
PMID:27935865
NCBI chr 2:245,624,460...246,359,605
Ensembl chr 2:245,624,435...246,356,730
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Nexn
nexilin (F actin binding protein)
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NEXN mRNA
CTD
PMID:27935865
NCBI chr 2:241,186,783...241,218,315
Ensembl chr 2:241,186,790...241,218,342
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Nfe2l2
NFE2 like bZIP transcription factor 2
multiple interactions
ISO
NFE2L2 protein promotes the reaction [Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NQO1 mRNA]]; NFE2L2 protein promotes the reaction [Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NQO1 protein]]; Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NFE2L2 mRNA]; Pioglitazone promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NFE2L2 mRNA]
CTD
PMID:30965670
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nfkbib
NFKB inhibitor beta
multiple interactions
ISO
pioglitazone inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIB protein]
CTD
PMID:17055343
NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
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Nkain3
Sodium/potassium transporting ATPase interacting 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NKAIN3 mRNA
CTD
PMID:27935865
NCBI chr 5:33,613,720...34,310,090
Ensembl chr 5:33,623,713...34,309,381
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Nkx3-1
NK3 homeobox 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NKX3-1 mRNA
CTD
PMID:27935865
NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441
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Nmrk2
nicotinamide riboside kinase 2
decreases expression
ISO
Pioglitazone results in decreased expression of NMRK2 mRNA
CTD
PMID:30031879
NCBI chr 7:8,514,855...8,517,916
Ensembl chr 7:8,514,927...8,517,922
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Nos2
nitric oxide synthase 2
multiple interactions decreases expression affects expression
ISO EXP
pioglitazone inhibits the reaction [Homocysteine results in increased methylation of NOS2 promoter] Pioglitazone inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of NOS2 protein]; Pioglitazone inhibits the reaction [Endotoxins results in increased expression of NOS2 protein] pioglitazone results in decreased expression of NOS2 mRNA pioglitazone affects the expression of NOS2
CTD
PMID:15364003 PMID:15817521 PMID:17492134 PMID:21962020 PMID:30343038
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Nos3
nitric oxide synthase 3
multiple interactions
EXP
Pioglitazone inhibits the reaction [[Dietary Fats co-treated with Fructose] results in decreased expression of NOS3 protein]
CTD
PMID:30343038
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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Nox1
NADPH oxidase 1
affects activity
ISO
pioglitazone affects the activity of NOX1 protein
CTD
PMID:21962020
NCBI chr X:97,279,058...97,332,291
Ensembl chr X:97,279,056...97,302,236
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Nox4
NADPH oxidase 4
multiple interactions
EXP
pioglitazone inhibits the reaction [Streptozocin results in increased expression of NOX4 mRNA]
CTD
PMID:16979161
NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
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Nppb
natriuretic peptide B
decreases expression
ISO
Pioglitazone results in decreased expression of NPPB mRNA
CTD
PMID:30031879
NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
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Npy
neuropeptide Y
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of NPY mRNA
CTD
PMID:27935865
NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
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Npy1r
neuropeptide Y receptor Y1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NPY1R mRNA
CTD
PMID:27935865
NCBI chr16:23,037,788...23,047,330
Ensembl chr16:23,037,789...23,046,759
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Nqo1
NAD(P)H quinone dehydrogenase 1
multiple interactions
ISO
NFE2L2 protein promotes the reaction [Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NQO1 mRNA]]; NFE2L2 protein promotes the reaction [Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NQO1 protein]]; Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NQO1 mRNA]; Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of NQO1 protein]; Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NQO1 mRNA]
CTD
PMID:30965670
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nr1h2
nuclear receptor subfamily 1, group H, member 2
increases expression
ISO
pioglitazone results in increased expression of NR1H2 mRNA
CTD
PMID:19201410
NCBI chr 1:95,041,967...95,047,358
Ensembl chr 1:95,041,967...95,047,377
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Nr1h3
nuclear receptor subfamily 1, group H, member 3
multiple interactions affects response to substance increases expression
ISO
22-hydroxycholesterol promotes the reaction [pioglitazone results in increased expression of NR1H3 mRNA]; NR1H3 protein affects the reaction [pioglitazone results in increased expression of PPARA mRNA] NR1H3 protein affects the susceptibility to pioglitazone
CTD
PMID:15381068 PMID:19201410
NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
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Nr1i2
nuclear receptor subfamily 1, group I, member 2
affects localization
ISO
Pioglitazone affects the localization of NR1I2 protein
CTD
PMID:31233785
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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Nr4a1
nuclear receptor subfamily 4, group A, member 1
increases expression
ISO
pioglitazone results in increased expression of NR4A1 mRNA
CTD
PMID:17785466
NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297
G
Nr4a3
nuclear receptor subfamily 4, group A, member 3
increases expression
ISO
pioglitazone results in increased expression of NR4A3 mRNA
CTD
PMID:17785466
NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733
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Nrap
nebulin-related anchoring protein
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NRAP mRNA
CTD
PMID:27935865
NCBI chr 1:255,350,113...255,427,704
Ensembl chr 1:255,350,113...255,427,693
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Nsg2
neuronal vesicle trafficking associated 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of NSG2 mRNA
CTD
PMID:27935865
NCBI chr10:15,601,594...15,661,441
Ensembl chr10:15,601,596...15,661,441
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Nucb2
nucleobindin 2
increases stability
ISO
pioglitazone results in increased stability of NUCB2 mRNA
CTD
PMID:20427483
NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353
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Obscn
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of OBSCN mRNA
CTD
PMID:27935865
NCBI chr10:43,774,113...43,919,718
Ensembl chr10:43,789,293...43,919,723
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Ogg1
8-oxoguanine DNA glycosylase
multiple interactions
ISO
Pioglitazone inhibits the reaction [LEPR protein affects the expression of OGG1 protein]
CTD
PMID:35472412
NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
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Olfml1
olfactomedin-like 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of OLFML1 mRNA
CTD
PMID:27935865
NCBI chr 1:161,478,129...161,502,541
Ensembl chr 1:161,478,242...161,502,537
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Opcml
opioid binding protein/cell adhesion molecule-like
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of OPCML mRNA
CTD
PMID:27935865
NCBI chr 8:26,788,988...27,304,551
Ensembl chr 8:26,192,841...27,300,620
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Optc
opticin
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of OPTC mRNA
CTD
PMID:27935865
NCBI chr13:45,353,954...45,368,254
Ensembl chr13:45,355,148...45,365,237
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Pax1
paired box 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PAX1 mRNA
CTD
PMID:27935865
NCBI chr 3:134,792,330...134,801,637
Ensembl chr 3:134,789,182...134,801,636
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Pcdh18
protocadherin 18
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PCDH18 mRNA
CTD
PMID:27935865
NCBI chr 2:133,831,996...133,845,992
Ensembl chr 2:133,832,001...133,845,883
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Pck1
phosphoenolpyruvate carboxykinase 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PCK1 mRNA
CTD
PMID:27935865
NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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Pclo
piccolo (presynaptic cytomatrix protein)
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PCLO mRNA
CTD
PMID:27935865
NCBI chr 4:19,691,439...20,050,015
Ensembl chr 4:19,695,315...20,049,885
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PCOLCE2
procollagen C-endopeptidase enhancer 2
increases expression
ISO
Pioglitazone results in increased expression of PCOLCE2 mRNA
CTD
PMID:30031879
NCBI chr 8:96,193,461...96,251,116
Ensembl chr 8:96,193,461...96,251,114
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Pcsk9
proprotein convertase subtilisin/kexin type 9
multiple interactions increases expression
ISO
pioglitazone promotes the reaction [PPARG protein results in increased expression of PCSK9 mRNA] pioglitazone results in increased expression of PCSK9 mRNA; pioglitazone results in increased expression of PCSK9 protein [pioglitazone co-treated with U 0126] results in increased secretion of PCSK9 protein
CTD
PMID:22593575
NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
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Pde6c
phosphodiesterase 6C
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PDE6C mRNA
CTD
PMID:27935865
NCBI chr 1:235,909,583...235,965,435
Ensembl chr 1:235,909,775...235,965,315
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Pdgfb
platelet derived growth factor subunit B
multiple interactions
ISO
[PDGFB protein binds to PDGFB protein] inhibits the reaction [pioglitazone results in decreased phosphorylation of MAPK1 protein]; [PDGFB protein binds to PDGFB protein] inhibits the reaction [pioglitazone results in decreased phosphorylation of MAPK3 protein]; pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased degradation of CDKN1B protein]; pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of CCND1 protein]; pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of CDKN1A protein]; pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of EIF4EBP1 protein]; pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6 protein]; pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6KB1 protein]; PRKAA1 protein affects the reaction [pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6 protein]]
CTD
PMID:26643070
NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
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Pdgfra
platelet derived growth factor receptor alpha
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PDGFRA mRNA
CTD
PMID:27935865
NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335
G
Pdk4
pyruvate dehydrogenase kinase 4
increases expression
ISO
Pioglitazone results in increased expression of PDK4 mRNA
CTD
PMID:30031879
NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
G
Peg10
paternally expressed 10
increases expression
ISO
Pioglitazone results in increased expression of PEG10 mRNA
CTD
PMID:30031879
NCBI chr 4:32,842,441...32,855,639
Ensembl chr 4:32,848,493...32,852,621
G
Perm1
PPARGC1 and ESRR induced regulator, muscle 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PERM1 mRNA
CTD
PMID:27935865
NCBI chr 5:166,800,030...166,805,323
Ensembl chr 5:166,800,030...166,805,323
G
Pgam2
phosphoglycerate mutase 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PGAM2 mRNA
CTD
PMID:27935865
NCBI chr14:80,681,796...80,683,907
Ensembl chr14:80,681,776...80,683,940
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Pgm5
phosphoglucomutase 5
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PGM5 mRNA
CTD
PMID:27935865
NCBI chr 1:222,325,638...222,513,434
Ensembl chr 1:222,325,643...222,513,437
G
Phactr1
phosphatase and actin regulator 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PHACTR1 mRNA
CTD
PMID:27935865
NCBI chr17:21,560,364...22,040,166
Ensembl chr17:21,562,721...22,039,831
G
Pheta2
PH domain containing endocytic trafficking adaptor 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PHETA2 mRNA
CTD
PMID:27935865
NCBI chr 7:113,855,437...113,861,910
Ensembl chr 7:113,857,249...113,861,871
G
Phex
phosphate regulating endopeptidase X-linked
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PHEX mRNA
CTD
PMID:27935865
NCBI chr X:37,607,553...37,856,183
Ensembl chr X:37,610,760...37,854,469
G
Phgr1
proline, histidine and glycine rich 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of PHGR1 mRNA
CTD
PMID:27935865
NCBI chr 3:105,742,822...105,760,835
Ensembl chr 3:105,757,581...105,760,832
G
Pid1
phosphotyrosine interaction domain containing 1
increases expression
ISO
Pioglitazone results in increased expression of PID1 mRNA
CTD
PMID:32816093
NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044
G
Piezo2
piezo-type mechanosensitive ion channel component 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PIEZO2 mRNA
CTD
PMID:27935865
NCBI chr18:56,468,449...56,844,984
Ensembl chr18:56,469,680...56,844,216
G
Pik3c3
phosphatidylinositol 3-kinase, catalytic subunit type 3
multiple interactions
ISO
[Metformin co-treated with Pioglitazone] results in decreased expression of PIK3C3 mRNA
CTD
PMID:32589349
NCBI chr18:21,845,282...21,934,387
Ensembl chr18:21,845,295...21,929,048
G
Pik3ca
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
multiple interactions decreases expression
ISO
[Metformin co-treated with Pioglitazone] results in decreased expression of PIK3CA mRNA Pioglitazone results in decreased expression of PIK3CA mRNA
CTD
PMID:32589349
NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
G
Pik3cb
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
multiple interactions
ISO
[Metformin co-treated with Pioglitazone] results in decreased expression of PIK3CB mRNA
CTD
PMID:32589349
NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
G
Pik3cg
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
multiple interactions
ISO
[Metformin co-treated with Pioglitazone] results in decreased expression of PIK3CG mRNA
CTD
PMID:32589349
NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043
G
Pknox2
PBX/knotted 1 homeobox 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PKNOX2 mRNA
CTD
PMID:27935865
NCBI chr 8:36,600,633...36,863,131
Ensembl chr 8:36,600,636...36,790,940
G
Plaat1
phospholipase A and acyltransferase 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of PLAAT1 mRNA
CTD
PMID:27935865
NCBI chr11:71,517,492...71,537,142
Ensembl chr11:71,517,493...71,527,020
G
Pld1
phospholipase D1
decreases expression multiple interactions
ISO
Pioglitazone results in decreased expression of PLD1 mRNA [Metformin co-treated with Pioglitazone] results in decreased expression of PLD1 mRNA
CTD
PMID:32589349
NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692
G
Plek
pleckstrin
decreases expression
ISO
Pioglitazone results in decreased expression of PLEK mRNA
CTD
PMID:30031879
NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
G
Plin1
perilipin 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of PLIN1 mRNA; Pioglitazone promotes the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of PLIN1 mRNA]
CTD
PMID:27935865 PMID:32473317
NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
G
Plin2
perilipin 2
increases expression
ISO
Pioglitazone results in increased expression of PLIN2 mRNA
CTD
PMID:15381068 PMID:30031879
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
G
Plin4
perilipin 4
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PLIN4 mRNA
CTD
PMID:27935865
NCBI chr 9:929,168...938,062
Ensembl chr 9:929,176...938,056
G
Pln
phospholamban
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PLN mRNA
CTD
PMID:27935865
NCBI chr20:32,629,537...32,639,559
G
Pnma8b
PNMA family member 8B
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of PNMA8B mRNA
CTD
PMID:27935865
NCBI chr 1:77,622,287...77,626,525
Ensembl chr 1:77,622,283...77,627,148
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Por
cytochrome p450 oxidoreductase
increases expression
EXP
pioglitazone results in increased expression of POR mRNA
CTD
PMID:16597547
NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
G
Ppara
peroxisome proliferator activated receptor alpha
multiple interactions increases expression affects response to substance affects binding increases activity
EXP ISO
pioglitazone binds to and results in increased activity of PPARA protein NR1H3 protein affects the reaction [pioglitazone results in increased expression of PPARA mRNA]; pioglitazone results in increased activity of [PPARA protein binds to RXRA protein] pioglitazone results in increased expression of PPARA mRNA; pioglitazone results in increased expression of PPARA protein PPARA protein affects the susceptibility to pioglitazone pioglitazone binds to PPARA protein pioglitazone results in increased activity of PPARA protein
CTD
PMID:11172467 PMID:11779144 PMID:15273253 PMID:16751799 PMID:19201410 PMID:23150725 PMID:23843199 More...
NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
G
Ppard
peroxisome proliferator-activated receptor delta
affects binding increases expression multiple interactions increases activity
ISO
pioglitazone binds to PPARB protein; pioglitazone binds to PPARD protein pioglitazone results in increased expression of PPARD mRNA pioglitazone results in increased activity of [PPARD protein binds to RXRA protein] pioglitazone results in increased activity of PPARD protein
CTD
PMID:11779144 PMID:19201410 PMID:23150725 PMID:23843199
NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
G
Pparg
peroxisome proliferator-activated receptor gamma
multiple interactions affects expression affects response to substance increases activity increases expression affects binding
ISO EXP
[Dexamethasone co-treated with INS protein co-treated with Pioglitazone] results in increased expression of PPARG protein; Ethanol inhibits the reaction [Pioglitazone results in increased activity of PPARG protein]; GW 1929 inhibits the reaction [Pioglitazone results in increased expression of PPARG protein]; luzindole inhibits the reaction [Pioglitazone results in increased expression of PPARG protein]; Melatonin promotes the reaction [Pioglitazone results in increased expression of PPARG protein]; Pioglitazone binds to and results in increased activity of PPARG protein; Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of PPARG protein]; Pioglitazone inhibits the reaction [GW 1929 binds to PPARG protein]; Pioglitazone promotes the reaction [Melatonin results in increased expression of PPARG protein]; Pioglitazone promotes the reaction [PPARG protein binds to NPHS1 promoter]; Pioglitazone promotes the reaction [PPARG protein results in increased expression of PCSK9 mRNA]; Pioglitazone results in increased activity of [PPARG protein alternative form binds to RXRA protein]; PPARG protein affects the reaction [Pioglitazone results in increased expression of CD36 protein]; PPARG protein promotes the reaction [Pioglitazone results in increased activity of DIO2 protein]; Ro 41-5253 inhibits the reaction [Pioglitazone results in increased activity of PPARG protein] [ANGPT2 protein binds to and results in increased activity of AGTR2 protein] promotes the reaction [pioglitazone binds to and results in increased activity of PPARG protein]; [Dexamethasone co-treated with INS protein co-treated with pioglitazone] results in increased expression of PPARG protein; [pioglitazone binds to and results in increased activity of PPARG protein] which results in increased expression of RETSAT mRNA; [pioglitazone co-treated with alitretinoin] inhibits the reaction [PPARG protein results in increased susceptibility to Methamphetamine]; pioglitazone binds to and results in increased activity of PPARG protein; pioglitazone inhibits the reaction [PPARG protein results in increased susceptibility to Methamphetamine]; pioglitazone promotes the reaction [PPARG protein binds to SCNN1G intron]; pioglitazone promotes the reaction [Toluene 2,4-Diisocyanate results in increased localization of PPARG protein]; pioglitazone results in increased activity of and results in decreased expression of PPARG protein; PPARG protein affects the reaction [pioglitazone results in increased expression of ADIPOQ mRNA] pioglitazone affects the expression of PPARG; pioglitazone affects the expression of PPARG mRNA 2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone affects the expression of PPARG mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone affects the expression of PPARG protein]; [naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in decreased expression of PPARG mRNA]; [Pioglitazone binds to and results in increased activity of PPARG protein] promotes the reaction [Dietary Fats results in increased abundance of Diglycerides]; [Pioglitazone binds to and results in increased activity of PPARG protein] promotes the reaction [Dietary Fats results in increased abundance of Phospholipids]; [Pioglitazone binds to and results in increased activity of PPARG protein] promotes the reaction [Dietary Fats results in increased abundance of Triglycerides]; [Pioglitazone results in increased activity of PPARG protein] which results in decreased abundance of Triglycerides; [Pioglitazone results in increased activity of PPARG protein] which results in increased abundance of Diglycerides; Pioglitazone affects the reaction [Puromycin Aminonucleoside results in increased expression of PPARG protein]; Pioglitazone binds to and results in increased activity of PPARG protein; Pioglitazone inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [Carbon Tetrachloride results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [Cisplatin results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [Fructose results in decreased activity of PPARG protein]; Pioglitazone inhibits the reaction [Quinolinic Acid results in decreased expression of PPARG mRNA]; Pioglitazone inhibits the reaction [Streptozocin results in decreased expression of PPARG protein]; T 0070907 inhibits the reaction [Pioglitazone affects the expression of PPARG mRNA]; T 0070907 inhibits the reaction [Pioglitazone affects the expression of PPARG protein] PPARG protein affects the susceptibility to pioglitazone pioglitazone results in increased activity of PPARG protein Pioglitazone results in increased expression of PPARG mRNA; Pioglitazone results in increased expression of PPARG mRNA alternative form; Pioglitazone results in increased expression of PPARG protein pioglitazone results in increased expression of PPARG mRNA Pioglitazone binds to PPARG protein pioglitazone affects the expression of PPARG mRNA; pioglitazone affects the expression of PPARG protein
CTD
PMID:9836514 PMID:11172467 PMID:11779144 PMID:11991651 PMID:12055599 PMID:12927809 PMID:15150131 PMID:15273253 PMID:15318101 PMID:15729575 PMID:15992368 PMID:16007095 PMID:16324916 PMID:16407166 PMID:16598202 PMID:16687628 PMID:16751799 PMID:17015710 PMID:17019405 PMID:17030193 PMID:17084873 PMID:17290005 PMID:19036883 PMID:19048458 PMID:19139408 PMID:19201410 PMID:19403437 PMID:19439812 PMID:20064974 PMID:20307981 PMID:20860658 PMID:21354099 PMID:21557540 PMID:21597168 PMID:21962020 PMID:22070604 PMID:22593575 PMID:22989705 PMID:23150725 PMID:23795773 PMID:23811337 PMID:23843199 PMID:25679220 PMID:26643070 PMID:27350165 PMID:28744220 PMID:29669060 PMID:29734669 PMID:30130594 PMID:30965670 PMID:31016361 PMID:32407875 PMID:32473317 PMID:37044004 More...
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
G
Ppargc1a
PPARG coactivator 1 alpha
decreases expression multiple interactions
EXP ISO
pioglitazone results in decreased expression of PPARGC1A mRNA Pioglitazone inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of PPARGC1A protein]
CTD
PMID:22456468 PMID:27366949
NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
G
Ppbp
pro-platelet basic protein
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of PPBP mRNA
CTD
PMID:27935865
NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130
G
Ppp1r3a
protein phosphatase 1, regulatory subunit 3A
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PPP1R3A mRNA
CTD
PMID:27935865
NCBI chr 4:42,937,353...42,980,195
Ensembl chr 4:42,939,599...42,980,638
G
Ppp1r3c
protein phosphatase 1, regulatory subunit 3C
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PPP1R3C mRNA
CTD
PMID:27935865
NCBI chr 1:234,460,958...234,465,961
Ensembl chr 1:234,460,652...234,465,961
G
Ppp2ca
protein phosphatase 2 catalytic subunit alpha
increases expression
ISO
Pioglitazone results in increased expression of PPP2CA mRNA
CTD
PMID:32589349
NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
G
Ppp2r2b
protein phosphatase 2, regulatory subunit B, beta
increases expression
ISO
Pioglitazone results in increased expression of PPP2R2B mRNA
CTD
PMID:32589349
NCBI chr18:34,653,716...35,080,889
Ensembl chr18:34,653,721...35,081,025
G
Prkaa1
protein kinase AMP-activated catalytic subunit alpha 1
multiple interactions
ISO
PRKAA1 protein affects the reaction [pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6 protein]]; PRKAA1 protein affects the reaction [pioglitazone results in increased expression of CDKN1B protein]; PRKAA1 protein affects the reaction [pioglitazone results in increased phosphorylation of RPTOR protein]
CTD
PMID:26643070
NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
G
Prkca
protein kinase C, alpha
multiple interactions decreases expression
ISO
[Metformin co-treated with Pioglitazone] results in decreased expression of PRKCA mRNA Pioglitazone results in decreased expression of PRKCA mRNA
CTD
PMID:32589349
NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
G
Prkcg
protein kinase C, gamma
increases expression
ISO
Pioglitazone results in increased expression of PRKCG mRNA
CTD
PMID:32589349
NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384
G
Prkcq
protein kinase C, theta
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PRKCQ mRNA
CTD
PMID:27935865
NCBI chr17:67,246,394...67,379,049
Ensembl chr17:67,246,394...67,378,704
G
Prkg1
protein kinase cGMP-dependent 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PRKG1 mRNA
CTD
PMID:27935865
NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080
G
Prnp
prion protein
increases expression multiple interactions
ISO
Pioglitazone results in increased expression of PRNP protein GW 1929 inhibits the reaction [Pioglitazone results in increased expression of PRNP protein]; luzindole inhibits the reaction [Pioglitazone results in increased expression of PRNP protein]; Melatonin promotes the reaction [Pioglitazone results in increased expression of PRNP protein]; Pioglitazone promotes the reaction [Melatonin results in increased expression of PRNP protein]; PRNP protein promotes the reaction [Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in decreased expression of RGN protein]]]; PRNP protein promotes the reaction [Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in increased expression of CDKN1A protein]]]; PRNP protein promotes the reaction [Pioglitazone promotes the reaction [Melatonin inhibits the reaction [Indican results in decreased expression of RGN protein]]]; PRNP protein promotes the reaction [Pioglitazone promotes the reaction [Melatonin inhibits the reaction [Indican results in increased expression of CDKN1A protein]]]
CTD
PMID:29734669
NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
G
Prok2
prokineticin 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of PROK2 mRNA
CTD
PMID:27935865
NCBI chr 4:132,346,681...132,361,754
Ensembl chr 4:132,347,103...132,361,385
G
Prr32
proline rich 32
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PRR32 mRNA
CTD
PMID:27935865
NCBI chr X:123,978,010...123,979,928
Ensembl chr X:123,977,985...123,979,942
G
Prr33
proline rich 33
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PRR33 mRNA
CTD
PMID:27935865
NCBI chr 1:197,644,903...197,650,774
Ensembl chr 1:197,644,902...197,650,714
G
Prxl2b
peroxiredoxin like 2B
decreases expression
ISO
Pioglitazone results in decreased expression of PRXL2B mRNA
CTD
PMID:30031879
NCBI chr 5:165,462,610...165,465,213
G
Psors1c2
psoriasis susceptibility 1 candidate 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of PSORS1C2 mRNA
CTD
PMID:27935865
NCBI chr20:3,202,178...3,203,599
Ensembl chr20:3,202,174...3,203,599
G
Pten
phosphatase and tensin homolog
increases expression
ISO
Pioglitazone results in increased expression of PTEN mRNA
CTD
PMID:32589349
NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
G
Ptgfr
prostaglandin F receptor
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PTGFR mRNA
CTD
PMID:27935865
NCBI chr 2:240,731,185...240,766,674
Ensembl chr 2:240,733,375...240,765,650
G
Ptgs2
prostaglandin-endoperoxide synthase 2
multiple interactions decreases expression increases expression
EXP ISO
[Atorvastatin co-treated with Pioglitazone] results in increased expression of PTGS2 protein pioglitazone results in decreased expression of PTGS2 mRNA pioglitazone results in decreased expression of PTGS2 protein Pioglitazone results in increased expression of PTGS2 mRNA
CTD
PMID:15817521 PMID:16386242 PMID:16908763 PMID:32816093
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
G
Pvalb
parvalbumin
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PVALB mRNA
CTD
PMID:27935865
NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561
G
Pxmp2
peroxisomal membrane protein 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PXMP2 mRNA
CTD
PMID:27935865
NCBI chr12:46,394,051...46,404,561
Ensembl chr12:46,394,193...46,404,557
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Pygm
glycogen phosphorylase, muscle associated
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of PYGM mRNA
CTD
PMID:27935865
NCBI chr 1:203,690,550...203,705,369
Ensembl chr 1:203,690,533...203,705,368
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Ralyl
RALY RNA binding protein-like
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RALYL mRNA
CTD
PMID:27935865
NCBI chr 2:87,482,747...88,274,329
Ensembl chr 2:87,482,755...88,274,452
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Ranbp2
RAN binding protein 2
multiple interactions
ISO
pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of RANBP2 mRNA]
CTD
PMID:20847119
NCBI chr20:26,442,156...26,493,481
Ensembl chr20:26,442,217...26,493,481
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Rasd2
RASD family, member 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RASD2 mRNA
CTD
PMID:27935865
NCBI chr19:13,594,291...13,605,016
Ensembl chr19:13,594,291...13,605,016
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Rasl12
RAS-like, family 12
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RASL12 mRNA
CTD
PMID:27935865
NCBI chr 8:65,917,840...65,931,885
Ensembl chr 8:65,917,840...65,932,741
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Rb1
RB transcriptional corepressor 1
multiple interactions
ISO
pioglitazone results in decreased phosphorylation of and results in decreased expression of RB1 protein
CTD
PMID:15729575
NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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Rcan2
regulator of calcineurin 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RCAN2 mRNA
CTD
PMID:27935865
NCBI chr 9:16,959,478...17,174,823
Ensembl chr 9:16,959,480...17,174,856
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Rdh10
retinol dehydrogenase 10
increases expression
ISO
Pioglitazone results in increased expression of RDH10 mRNA
CTD
PMID:30031879
NCBI chr 5:3,186,671...3,215,572
Ensembl chr 5:3,188,445...3,215,572
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Reep3
receptor accessory protein 3
multiple interactions
ISO
pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of REEP3 mRNA]
CTD
PMID:20847119
NCBI chr20:21,493,868...21,578,698
Ensembl chr20:21,493,954...21,578,697
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Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions affects expression
ISO EXP
pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased localization of RELA protein] 2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone affects the expression of RELA mRNA]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Pioglitazone affects the expression of RELA protein]; Fenofibrate promotes the reaction [Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of RELA protein]]; Pioglitazone inhibits the reaction [Aldosterone results in increased activity of RELA protein]; Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of RELA protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of RELA mRNA]; Pioglitazone promotes the reaction [Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of RELA protein]]; T 0070907 inhibits the reaction [Pioglitazone affects the expression of RELA mRNA]; T 0070907 inhibits the reaction [Pioglitazone affects the expression of RELA protein] Pioglitazone affects the expression of RELA mRNA; Pioglitazone affects the expression of RELA protein
CTD
PMID:17015710 PMID:18660453 PMID:28744220 PMID:36988379 PMID:37044004
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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Retn
resistin
multiple interactions increases expression increases secretion
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of RETN mRNA; Pioglitazone inhibits the reaction [Sodium Glutamate results in increased expression of RETN mRNA]; Pioglitazone inhibits the reaction [Sodium Glutamate results in increased secretion of RETN protein] Pioglitazone results in increased expression of RETN mRNA Pioglitazone results in increased secretion of RETN protein
CTD
PMID:27918843 PMID:27935865
NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
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Retsat
retinol saturase
multiple interactions increases expression
ISO
[pioglitazone binds to and results in increased activity of PPARG protein] which results in increased expression of RETSAT mRNA Pioglitazone results in increased expression of RETSAT mRNA; Pioglitazone results in increased expression of RETSAT protein
CTD
PMID:19139408
NCBI chr 4:104,653,306...104,662,069
Ensembl chr 4:104,653,155...104,668,310
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Rgcc
regulator of cell cycle
decreases expression
ISO
Pioglitazone results in decreased expression of RGCC mRNA
CTD
PMID:30031879
NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141
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Rgn
regucalcin
multiple interactions
ISO
Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in decreased expression of RGN protein]]; Pioglitazone inhibits the reaction [Indican results in decreased expression of RGN protein]; Pioglitazone promotes the reaction [Melatonin inhibits the reaction [Indican results in decreased expression of RGN protein]]; PRNP protein promotes the reaction [Melatonin promotes the reaction [Pioglitazone inhibits the reaction [Indican results in decreased expression of RGN protein]]]; PRNP protein promotes the reaction [Pioglitazone promotes the reaction [Melatonin inhibits the reaction [Indican results in decreased expression of RGN protein]]]
CTD
PMID:29734669
NCBI chr X:1,619,030...1,634,456
Ensembl chr X:1,619,032...1,634,450
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Rgs1
regulator of G-protein signaling 1
decreases expression
ISO
Pioglitazone results in decreased expression of RGS1 mRNA
CTD
PMID:30031879
NCBI chr13:56,018,546...56,022,889
Ensembl chr13:56,018,554...56,022,984
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Rgs13
regulator of G-protein signaling 13
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RGS13 mRNA
CTD
PMID:27935865
NCBI chr13:55,922,290...55,955,753
Ensembl chr13:55,922,395...55,955,648
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Rgs5
regulator of G-protein signaling 5
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RGS5 mRNA
CTD
PMID:27935865
NCBI chr13:81,848,254...81,885,053
Ensembl chr13:81,836,304...81,885,518
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Rgs7bp
regulator of G-protein signaling 7 binding protein
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RGS7BP mRNA
CTD
PMID:27935865
NCBI chr 2:36,133,944...36,231,505
Ensembl chr 2:36,139,201...36,231,505
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Rheb
Ras homolog, mTORC1 binding
increases expression
ISO
Pioglitazone results in increased expression of RHEB mRNA
CTD
PMID:32589349
NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160
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Rictor
RPTOR independent companion of MTOR, complex 2
multiple interactions
ISO
[Metformin co-treated with Pioglitazone] results in decreased expression of RICTOR mRNA; Pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of RICTOR mRNA]
CTD
PMID:20847119 PMID:32589349
NCBI chr 2:55,811,877...55,903,893
Ensembl chr 2:55,811,322...55,901,426
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Riox1
ribosomal oxygenase 1
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of RIOX1 mRNA
CTD
PMID:20847119
NCBI chr 6:103,579,642...103,582,260
Ensembl chr 6:103,579,642...103,582,250
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Rnase6
ribonuclease A family member k6
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RNASE6 mRNA
CTD
PMID:27935865
NCBI chr15:24,354,305...24,357,289
Ensembl chr15:24,354,303...24,357,328
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Robo3
roundabout guidance receptor 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of ROBO3 mRNA
CTD
PMID:27935865
NCBI chr 8:37,133,542...37,151,674
Ensembl chr 8:37,133,916...37,151,315
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Rorc
RAR-related orphan receptor C
increases expression
ISO
pioglitazone results in increased expression of RORC mRNA
CTD
PMID:9543393
NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907
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Rpl3l
ribosomal protein L3-like
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RPL3L mRNA
CTD
PMID:27935865
NCBI chr10:13,753,914...13,764,458
Ensembl chr10:13,753,886...13,764,457
G
Rps6
ribosomal protein S6
decreases phosphorylation multiple interactions decreases expression
ISO
pioglitazone results in decreased phosphorylation of RPS6 protein pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6 protein]; PRKAA1 protein affects the reaction [pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6 protein]] Pioglitazone results in decreased expression of RPS6 mRNA
CTD
PMID:26643070 PMID:32589349
NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602 Ensembl chr 5:101,371,136...101,374,602
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Rps6ka1
ribosomal protein S6 kinase A1
increases expression
ISO
Pioglitazone results in increased expression of RPS6KA1 mRNA
CTD
PMID:32589349
NCBI chr 5:146,079,018...146,118,272
Ensembl chr 5:146,079,021...146,118,272
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Rps6ka2
ribosomal protein S6 kinase A2
increases expression multiple interactions
ISO
Pioglitazone results in increased expression of RPS6KA2 mRNA [Metformin co-treated with Pioglitazone] results in increased expression of RPS6KA2 mRNA
CTD
PMID:32589349
NCBI chr 1:52,631,582...52,906,739
Ensembl chr 1:52,631,736...52,906,739
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Rps6ka5
ribosomal protein S6 kinase A5
multiple interactions
ISO
[Metformin co-treated with Pioglitazone] results in decreased expression of RPS6KA5 mRNA
CTD
PMID:32589349
NCBI chr 6:119,828,823...120,006,190
Ensembl chr 6:119,828,846...120,006,224
G
Rps6kb1
ribosomal protein S6 kinase B1
multiple interactions decreases phosphorylation
ISO
pioglitazone inhibits the reaction [[PDGFB protein binds to PDGFB protein] which results in increased expression of RPS6KB1 protein] pioglitazone results in decreased phosphorylation of RPS6KB1 protein
CTD
PMID:26643070
NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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Rptor
regulatory associated protein of MTOR, complex 1
increases phosphorylation multiple interactions
ISO
pioglitazone results in increased phosphorylation of RPTOR protein PRKAA1 protein affects the reaction [pioglitazone results in increased phosphorylation of RPTOR protein]
CTD
PMID:26643070
NCBI chr10:104,878,487...105,176,986
Ensembl chr10:104,878,487...105,176,983
G
Rpusd2
RNA pseudouridine synthase domain containing 2
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of RPUSD2 mRNA
CTD
PMID:20847119
NCBI chr 3:106,017,759...106,023,010
Ensembl chr 3:106,017,864...106,023,251
G
Rspo1
R-spondin 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RSPO1 mRNA
CTD
PMID:27935865
NCBI chr 5:137,251,629...137,273,273
Ensembl chr 5:137,251,659...137,272,933
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Rtl3
retrotransposon Gag like 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RTL3 mRNA
CTD
PMID:27935865
NCBI chr X:71,947,343...71,951,008
Ensembl chr X:71,948,253...71,950,121
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Rtn2
reticulon 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RTN2 mRNA
CTD
PMID:27935865
NCBI chr 1:78,935,056...78,948,069
Ensembl chr 1:78,935,104...78,948,069
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Runx1t1
RUNX1 partner transcriptional co-repressor 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RUNX1T1 mRNA
CTD
PMID:27935865
NCBI chr 5:27,187,674...27,338,070
Ensembl chr 5:27,187,551...27,335,592
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Rxra
retinoid X receptor alpha
multiple interactions
ISO
pioglitazone results in increased activity of [PPARA protein binds to RXRA protein]; pioglitazone results in increased activity of [PPARD protein binds to RXRA protein]; pioglitazone results in increased activity of [PPARG protein alternative form binds to RXRA protein]
CTD
PMID:11779144
NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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Ryr1
ryanodine receptor 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of RYR1 mRNA
CTD
PMID:27935865
NCBI chr 1:84,292,578...84,423,824
Ensembl chr 1:84,292,578...84,423,812
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S100a8
S100 calcium binding protein A8
multiple interactions increases expression decreases expression
ISO
[pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of S100A8 mRNA pioglitazone results in increased expression of S100A8 mRNA Pioglitazone results in decreased expression of S100A8 mRNA
CTD
PMID:28138970 PMID:28263783 PMID:30031879
NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
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S100a9
S100 calcium binding protein A9
multiple interactions increases expression
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of S100A9 mRNA; [pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of S100A9 mRNA pioglitazone results in increased expression of S100A9 mRNA
CTD
PMID:27935865 PMID:28138970 PMID:28263783
NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
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Sbk2
SH3 domain binding kinase family, member 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SBK2 mRNA
CTD
PMID:27935865
NCBI chr 1:68,874,081...68,881,918
Ensembl chr 1:68,874,152...68,881,916
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Sbk3
SH3 domain binding kinase family, member 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SBK3 mRNA
CTD
PMID:27935865
NCBI chr 1:68,867,847...68,873,249
Ensembl chr 1:68,868,238...68,871,392
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Sbspon
somatomedin B and thrombospondin, type 1 domain containing
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SBSPON mRNA
CTD
PMID:27935865
NCBI chr 5:3,402,763...3,433,338
Ensembl chr 5:3,402,648...3,435,420
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Scarb1
scavenger receptor class B, member 1
decreases expression
ISO
pioglitazone results in decreased expression of SCARB1 mRNA
CTD
PMID:20503262
NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
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Scd
stearoyl-CoA desaturase
multiple interactions
ISO
Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]
CTD
PMID:32613381
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
G
Scgb3a2
secretoglobin, family 3A, member 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SCGB3A2 mRNA
CTD
PMID:27935865
NCBI chr18:35,932,840...35,935,762
Ensembl chr18:35,932,840...35,935,762
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Scn2a
sodium voltage-gated channel alpha subunit 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SCN2A mRNA
CTD
PMID:27935865
NCBI chr 3:50,302,781...50,437,504
Ensembl chr 3:50,302,877...50,437,214
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Scn4a
sodium voltage-gated channel alpha subunit 4
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SCN4A mRNA
CTD
PMID:27935865
NCBI chr10:91,246,936...91,296,670
Ensembl chr10:91,246,936...91,296,545
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Scn4b
sodium voltage-gated channel beta subunit 4
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SCN4B mRNA
CTD
PMID:27935865
NCBI chr 8:45,446,580...45,462,294
Ensembl chr 8:45,446,215...45,462,292
G
Scn7a
sodium voltage-gated channel alpha subunit 7
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SCN7A mRNA
CTD
PMID:27935865
NCBI chr 3:51,335,841...51,438,308
Ensembl chr 3:51,335,841...51,438,256
G
Scnn1g
sodium channel epithelial 1 subunit gamma
multiple interactions increases expression
ISO
pioglitazone promotes the reaction [PPARG protein binds to SCNN1G intron] pioglitazone results in increased expression of SCNN1G mRNA
CTD
PMID:16007095
NCBI chr 1:176,304,942...176,338,816
Ensembl chr 1:176,304,942...176,338,816
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Scube1
signal peptide, CUB domain and EGF like domain containing 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SCUBE1 mRNA
CTD
PMID:27935865
NCBI chr 7:114,759,016...114,880,995
Ensembl chr 7:114,759,010...114,880,940
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Sec31b
SEC31 homolog B, COPII coat complex component
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SEC31B mRNA
CTD
PMID:27935865
NCBI chr 1:243,376,283...243,404,557
Ensembl chr 1:243,378,456...243,404,557
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Sele
selectin E
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SELE mRNA
CTD
PMID:27935865
NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
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Selp
selectin P
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SELP mRNA
CTD
PMID:27935865
NCBI chr13:76,476,229...76,511,846
Ensembl chr13:76,476,295...76,511,845
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Serpine1
serpin family E member 1
multiple interactions increases expression
EXP ISO
pioglitazone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of SERPINE1 mRNA] pioglitazone results in increased expression of SERPINE1 mRNA
CTD
PMID:16598202 PMID:21757225
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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Sfrp2
secreted frizzled-related protein 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SFRP2 mRNA
CTD
PMID:27935865
NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
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Sfrp4
secreted frizzled-related protein 4
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SFRP4 mRNA
CTD
PMID:27935865
NCBI chr17:45,278,867...45,330,806
Ensembl chr17:45,234,097...45,330,736
G
Sftpa1
surfactant protein A1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SFTPA1 mRNA
CTD
PMID:27935865
NCBI chr16:17,008,180...17,011,686
Ensembl chr16:17,008,180...17,011,685
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Sgca
sarcoglycan, alpha
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SGCA mRNA
CTD
PMID:27935865
NCBI chr10:79,904,698...79,922,808
Ensembl chr10:79,908,738...79,922,813
G
Sgce
sarcoglycan, epsilon
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SGCE mRNA
CTD
PMID:27935865
NCBI chr 4:32,771,477...32,842,238
Ensembl chr 4:32,771,477...32,842,254
G
Sgcg
sarcoglycan, gamma
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SGCG mRNA
CTD
PMID:27935865
NCBI chr15:35,388,836...35,435,072
Ensembl chr15:35,386,534...35,435,148
G
Sgk1
serum/glucocorticoid regulated kinase 1
decreases expression
ISO
Pioglitazone results in decreased expression of SGK1 mRNA
CTD
PMID:32589349
NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
G
Sh2d5
SH2 domain containing 5
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SH2D5 mRNA
CTD
PMID:27935865
NCBI chr 5:150,469,738...150,480,615
Ensembl chr 5:150,467,728...150,479,955
G
Sh2d7
SH2 domain containing 7
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SH2D7 mRNA
CTD
PMID:27935865
NCBI chr 8:54,918,399...54,930,129
Ensembl chr 8:54,918,406...54,929,726
G
She
Src homology 2 domain containing E
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SHE mRNA
CTD
PMID:27935865
NCBI chr 2:175,262,431...175,287,807
Ensembl chr 2:175,262,442...175,286,669
G
Slc17a8
solute carrier family 17 member 8
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC17A8 mRNA
CTD
PMID:27935865
NCBI chr 7:23,994,212...24,049,498
Ensembl chr 7:23,994,217...24,048,079
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Slc22a2
solute carrier family 22 member 2
multiple interactions
ISO
pioglitazone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]
CTD
PMID:21599003
NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
G
Slc25a24
solute carrier family 25 member 24
decreases expression
ISO
Pioglitazone results in decreased expression of SLC25A24 mRNA
CTD
PMID:30031879
NCBI chr 2:196,761,076...196,799,236
Ensembl chr 2:196,761,274...196,799,231
G
Slc25a34
solute carrier family 25, member 34
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC25A34 mRNA
CTD
PMID:27935865
NCBI chr 5:153,932,081...153,936,854
G
Slc25a53
solute carrier family 25, member 53
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC25A53 mRNA
CTD
PMID:27935865
NCBI chr X:100,306,917...100,319,662
Ensembl chr X:100,306,915...100,319,863
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Slc26a7
solute carrier family 26 member 7
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC26A7 mRNA
CTD
PMID:27935865
NCBI chr 5:27,884,400...28,021,865
Ensembl chr 5:27,887,042...28,021,658
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Slc27a1
solute carrier family 27 member 1
increases expression
ISO
pioglitazone results in increased expression of SLC27A1 mRNA
CTD
PMID:20723549
NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
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Slc2a3
solute carrier family 2 member 3
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of SLC2A3 mRNA
CTD
PMID:20847119
NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
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Slc2a4
solute carrier family 2 member 4
multiple interactions
EXP
pioglitazone inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in decreased expression of SLC2A4 mRNA]
CTD
PMID:27350165
NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
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Slc2a5
solute carrier family 2 member 5
multiple interactions decreases expression
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC2A5 mRNA Pioglitazone results in decreased expression of SLC2A5 mRNA
CTD
PMID:27935865 PMID:30031879
NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106
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Slc2a6
solute carrier family 2 member 6
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SLC2A6 mRNA
CTD
PMID:27935865
NCBI chr 3:10,348,395...10,355,208
Ensembl chr 3:10,348,395...10,355,208
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Slc38a5
solute carrier family 38, member 5
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC38A5 mRNA
CTD
PMID:27935865
NCBI chr X:14,213,727...14,222,498
Ensembl chr X:14,213,729...14,222,498
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Slc4a5
solute carrier family 4 member 5
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC4A5 mRNA
CTD
PMID:27935865
NCBI chr 4:115,710,101...115,810,330
Ensembl chr 4:115,725,592...115,810,323
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Slc5a7
solute carrier family 5 member 7
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC5A7 mRNA
CTD
PMID:27935865
NCBI chr 9:7,595,440...7,626,258
Ensembl chr 9:7,595,444...7,626,258
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Slc6a12
solute carrier family 6 member 12
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SLC6A12 mRNA
CTD
PMID:27935865
NCBI chr 4:154,585,386...154,603,750
Ensembl chr 4:154,585,500...154,603,750
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Slc6a15
solute carrier family 6 member 15
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC6A15 mRNA
CTD
PMID:27935865
NCBI chr 7:38,553,055...38,607,239
Ensembl chr 7:38,553,196...38,607,239
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Slc6a17
solute carrier family 6 member 17
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLC6A17 mRNA
CTD
PMID:27935865
NCBI chr 2:195,107,434...195,155,697
Ensembl chr 2:195,107,438...195,155,697
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Slc7a11
solute carrier family 7 member 11
increases expression
ISO
Pioglitazone results in increased expression of SLC7A11 mRNA
CTD
PMID:32816093
NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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Slco1b2
solute carrier organic anion transporter family member 1B2
multiple interactions
ISO
pioglitazone affects the reaction [SLCO1B3 protein results in increased uptake of Sulfobromophthalein]
CTD
PMID:23121773
NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981
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Slco2b1
solute carrier organic anion transporter family, member 2b1
multiple interactions
ISO
Pioglitazone affects the reaction [SLCO2B1 protein results in increased uptake of Sulfobromophthalein]
CTD
PMID:23121773
NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353
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Slco4c1
solute carrier organic anion transporter family, member 4C1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLCO4C1 mRNA
CTD
PMID:27935865
NCBI chr 9:97,177,497...97,229,161
Ensembl chr 9:97,178,861...97,229,715
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Slco5a1
solute carrier organic anion transporter family, member 5A1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLCO5A1 mRNA
CTD
PMID:27935865
NCBI chr 5:6,228,938...6,358,124
Ensembl chr 5:6,228,973...6,352,913
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Slit1
slit guidance ligand 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SLIT1 mRNA
CTD
PMID:27935865
NCBI chr 1:240,409,559...240,558,127
Ensembl chr 1:240,409,561...240,558,127
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Sln
sarcolipin
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SLN mRNA
CTD
PMID:27935865
NCBI chr 8:54,221,389...54,248,110
Ensembl chr 8:54,243,542...54,247,791
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Sltm
SAFB-like, transcription modulator
multiple interactions
ISO
pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of SLTM mRNA]
CTD
PMID:20847119
NCBI chr 8:71,215,995...71,261,821
Ensembl chr 8:71,216,612...71,261,825
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Smad9
SMAD family member 9
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SMAD9 mRNA
CTD
PMID:27935865
NCBI chr 2:138,956,326...139,006,315
Ensembl chr 2:138,986,471...139,006,307
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Smim10l2a
small integral membrane protein 10 like 2A
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of SMIM10L2A mRNA
CTD
PMID:27935865
NCBI chr X:134,151,325...134,154,647
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Smoc1
SPARC related modular calcium binding 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SMOC1 mRNA
CTD
PMID:27935865
NCBI chr 6:100,701,330...100,897,441
Ensembl chr 6:100,701,346...100,862,699
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Smpx
small muscle protein, X-linked
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SMPX mRNA
CTD
PMID:27935865
NCBI chr X:37,233,209...37,292,266
Ensembl chr X:37,234,294...37,276,708
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Smtnl1
smoothelin-like 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SMTNL1 mRNA
CTD
PMID:27935865
NCBI chr 3:69,889,010...69,901,096
Ensembl chr 3:69,889,010...69,901,079
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Sncaip
synuclein, alpha interacting protein
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SNCAIP mRNA
CTD
PMID:27935865
NCBI chr18:46,205,846...46,343,932
Ensembl chr18:46,207,152...46,343,929
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Sod1
superoxide dismutase 1
increases expression multiple interactions
ISO
pioglitazone results in increased expression of SOD1 mRNA; pioglitazone results in increased expression of SOD1 protein pioglitazone inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in decreased expression of SOD1 mRNA]
CTD
PMID:11172467 PMID:18513333
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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Sod2
superoxide dismutase 2
affects activity
ISO
pioglitazone affects the activity of SOD2 protein
CTD
PMID:21962020
NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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Sorcs1
sortilin-related VPS10 domain containing receptor 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SORCS1 mRNA
CTD
PMID:27935865
NCBI chr 1:249,080,662...249,594,520
Ensembl chr 1:249,081,355...249,594,507
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Sowahc
sosondowah ankyrin repeat domain family member C
increases expression
ISO
Pioglitazone results in increased expression of SOWAHC mRNA
CTD
PMID:30031879
NCBI chr20:27,195,198...27,199,664
Ensembl chr20:27,193,743...27,265,018 Ensembl chr20:27,193,743...27,265,018
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Sox10
SRY-box transcription factor 10
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SOX10 mRNA
CTD
PMID:27935865
NCBI chr 7:110,725,274...110,734,651
Ensembl chr 7:110,725,274...110,735,544
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Sox8
SRY-box transcription factor 8
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SOX8 mRNA
CTD
PMID:27935865
NCBI chr10:14,584,829...14,589,818
Ensembl chr10:14,584,829...14,589,818
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Sp7
Sp7 transcription factor
multiple interactions
ISO
Pioglitazone inhibits the reaction [[Ascorbic Acid co-treated with beta-glycerophosphoric acid co-treated with Dexamethasone co-treated with INS protein] results in increased expression of SP7 mRNA]
CTD
PMID:32473317
NCBI chr 7:133,484,609...133,494,788
Ensembl chr 7:133,484,609...133,494,847
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Sparcl1
SPARC like 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SPARCL1 mRNA
CTD
PMID:27935865
NCBI chr14:5,632,816...5,663,866
Ensembl chr14:5,632,569...5,663,865
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Speg
striated muscle enriched protein kinase
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SPEG mRNA
CTD
PMID:27935865
NCBI chr 9:76,865,714...76,923,170
Ensembl chr 9:76,865,754...76,923,144
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Spink9
serine peptidase inhibitor, Kazal type 9
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SPINK12 mRNA
CTD
PMID:27935865
NCBI chr18:36,427,043...36,430,271
Ensembl chr18:36,426,989...36,430,271
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Spmip11
sperm microtubule inner protein 11
increases expression
EXP
Pioglitazone results in increased expression of NPHS1 mRNA; Pioglitazone results in increased expression of NPHS1 protein
CTD
PMID:16687628
NCBI chr 7:129,720,950...129,742,485
Ensembl chr 7:129,720,950...129,742,485
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Spocd1
SPOC domain containing 1
increases expression
ISO
Pioglitazone results in increased expression of SPOCD1 mRNA
CTD
PMID:30031879
NCBI chr 5:142,288,822...142,297,113
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Spon1
spondin 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SPON1 mRNA
CTD
PMID:27935865
NCBI chr 1:167,929,049...168,228,239
Ensembl chr 1:167,928,972...168,228,226
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Spp1
secreted phosphoprotein 1
multiple interactions
EXP
pioglitazone inhibits the reaction [Streptozocin results in increased expression of SPP1 mRNA]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of SPP1 protein]
CTD
PMID:16979161
NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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Sprr1b
small proline-rich protein 1B
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SPRR1B mRNA
CTD
PMID:27935865
NCBI chr 2:178,008,844...178,010,742
Ensembl chr 2:178,009,130...178,009,567
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Sprr2b
small proline rich protein 2B
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in increased expression of SPRR2B mRNA
CTD
PMID:27935865
NCBI chr 2:177,852,824...177,853,096
Ensembl chr 2:177,852,824...177,853,096
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Sprr2d
small proline-rich protein 2D
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SPRR2D mRNA
CTD
PMID:27935865
NCBI chr 2:177,870,082...177,870,679
Ensembl chr 2:177,870,434...177,870,679
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Sprr2f
small proline rich protein 2F
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SPRR2F mRNA
CTD
PMID:27935865
NCBI chr 2:177,989,974...177,990,204
Ensembl chr 2:177,989,974...177,990,204
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Srl
sarcalumenin
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SRL mRNA
CTD
PMID:27935865
NCBI chr10:11,033,976...11,078,103
Ensembl chr10:11,034,035...11,078,101
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Srpx
sushi-repeat-containing protein, X-linked
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SRPX mRNA
CTD
PMID:27935865
NCBI chr X:12,676,984...12,751,296
Ensembl chr X:12,566,645...12,747,882
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St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ST3GAL1 mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ST3GAL1 mRNA]
CTD
PMID:20847119
NCBI chr 7:98,845,270...98,913,409
Ensembl chr 7:98,845,270...98,913,236
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Stac3
SH3 and cysteine rich domain 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of STAC3 mRNA
CTD
PMID:27935865
NCBI chr 7:63,343,078...63,350,590
Ensembl chr 7:63,343,186...63,350,589
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Stk11
serine/threonine kinase 11
increases expression
ISO
Pioglitazone results in increased expression of STK11 mRNA
CTD
PMID:32589349
NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
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Stx1b
syntaxin 1B
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of STX1B mRNA
CTD
PMID:27935865
NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280
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Styxl2
serine/threonine/tyrosine interacting like 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of STYXL2 mRNA
CTD
PMID:27935865
NCBI chr13:78,349,361...78,378,480
Ensembl chr13:78,349,365...78,378,458
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Sult1c2a
sulfotransferase family 1C member 2A
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of SULT1C2 mRNA
CTD
PMID:27935865
NCBI chr 9:6,873,697...6,904,736
Ensembl chr 9:6,874,249...6,904,734
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Sult1c3
sulfotransferase family 1C member 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SULT1C1 mRNA
CTD
PMID:27935865
NCBI chr 9:7,221,580...7,266,991
Ensembl chr 9:7,221,578...7,267,030
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Susd5
sushi domain containing 5
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SUSD5 mRNA
CTD
PMID:27935865
NCBI chr 8:113,996,771...114,036,133
Ensembl chr 8:113,997,362...114,035,861
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Svep1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SVEP1 mRNA
CTD
PMID:27935865
NCBI chr 5:72,811,200...72,988,185
Ensembl chr 5:72,811,410...72,988,525
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Svopl
SVOP like
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SVOPL mRNA
CTD
PMID:27935865
NCBI chr 4:66,697,550...66,751,699
Ensembl chr 4:66,698,177...66,758,978
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Syn1
synapsin I
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of SYN1 mRNA
CTD
PMID:27935865
NCBI chr X:1,172,208...1,227,400
Ensembl chr X:1,172,208...1,227,396
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Syn2
synapsin II
multiple interactions
ISO
Pioglitazone inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SYN2 protein]
CTD
PMID:32735850
NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192
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Synpo2
synaptopodin 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SYNPO2 mRNA
CTD
PMID:27935865
NCBI chr 2:211,217,099...211,371,267
Ensembl chr 2:211,216,783...211,371,267
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Sypl2
synaptophysin-like 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of SYPL2 mRNA
CTD
PMID:27935865
NCBI chr 2:195,849,062...195,863,794
Ensembl chr 2:195,849,062...195,863,794
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Tagln
transgelin
multiple interactions decreases expression
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TAGLN mRNA Pioglitazone results in decreased expression of TAGLN mRNA
CTD
PMID:27935865 PMID:30031879
NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
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Tarm1
T cell-interacting, activating receptor on myeloid cells 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of TARM1 mRNA
CTD
PMID:27935865
NCBI chr 1:65,666,742...65,682,402
Ensembl chr 1:65,671,902...65,679,626
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Tas2r108
taste receptor, type 2, member 108
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TAS2R108 mRNA
CTD
PMID:27935865
NCBI chr 4:69,287,667...69,288,581
Ensembl chr 4:69,287,667...69,288,581
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Tbx15
T-box transcription factor 15
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TBX15 mRNA
CTD
PMID:27935865
NCBI chr 2:186,576,650...186,687,748
Ensembl chr 2:186,576,676...186,687,663
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Tbx4
T-box transcription factor 4
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TBX4 mRNA
CTD
PMID:27935865
NCBI chr10:70,730,686...70,760,829
Ensembl chr10:70,731,163...70,760,825
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Tcap
titin-cap
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TCAP mRNA
CTD
PMID:27935865
NCBI chr10:83,381,719...83,382,887
Ensembl chr10:83,381,719...83,382,887
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Tceal7
transcription elongation factor A like 7
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TCEAL7 mRNA
CTD
PMID:27935865
NCBI chr X:99,228,405...99,230,551
Ensembl chr X:99,228,458...99,230,543
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Tdh
L-threonine dehydrogenase
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of TDH mRNA
CTD
PMID:27935865
NCBI chr15:37,739,823...37,753,365
Ensembl chr15:37,739,823...37,753,365
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Tdo2
tryptophan 2,3-dioxygenase
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TDO2 mRNA
CTD
PMID:27935865
NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511
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Telo2
telomere maintenance 2
increases expression multiple interactions
ISO
Pioglitazone results in increased expression of TELO2 mRNA [Metformin co-treated with Pioglitazone] results in increased expression of TELO2 mRNA
CTD
PMID:32589349
NCBI chr10:14,120,491...14,135,729
Ensembl chr10:14,120,818...14,135,698
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Tet1
tet methylcytosine dioxygenase 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TET1 mRNA
CTD
PMID:27935865
NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052
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Tfam
transcription factor A, mitochondrial
decreases expression
ISO
pioglitazone results in decreased expression of TFAM mRNA
CTD
PMID:20860658
NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
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Tff2
trefoil factor 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TFF2 mRNA
CTD
PMID:27935865
NCBI chr20:9,215,750...9,219,619
Ensembl chr20:9,215,761...9,219,619
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Tg
thyroglobulin
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TG mRNA
CTD
PMID:27935865
NCBI chr 7:98,418,293...98,603,210
Ensembl chr 7:98,418,293...98,603,210
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Tgfb1
transforming growth factor, beta 1
multiple interactions decreases expression
ISO EXP
pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of TGFB1 protein] pioglitazone results in decreased expression of TGFB1 mRNA pioglitazone affects the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]; pioglitazone inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]; pioglitazone inhibits the reaction [Dimethylnitrosamine results in increased expression of TGFB1 mRNA] Pioglitazone inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 mRNA]
CTD
PMID:12055599 PMID:16484506 PMID:16611854 PMID:17015710 PMID:32613381
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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Tgm7
transglutaminase 7
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of TGM7 mRNA
CTD
PMID:27935865
NCBI chr 3:108,051,890...108,068,116
Ensembl chr 3:108,051,890...108,076,239
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Thbs1
thrombospondin 1
multiple interactions
EXP
pioglitazone inhibits the reaction [Streptozocin results in increased expression of THBS1 mRNA]; pioglitazone inhibits the reaction [Streptozocin results in increased expression of THBS1 protein]
CTD
PMID:17063547
NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440
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Thrsp
thyroid hormone responsive
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of THRSP mRNA
CTD
PMID:27935865
NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
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Timp1
TIMP metallopeptidase inhibitor 1
multiple interactions
EXP
pioglitazone affects the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]
CTD
PMID:16484506
NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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Tle6
TLE family member 6, subcortical maternal complex member
increases expression
ISO
Pioglitazone results in increased expression of TLE6 mRNA
CTD
PMID:30031879
NCBI chr 7:8,107,050...8,118,639
Ensembl chr 7:8,107,207...8,118,639
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Tlr11
toll-like receptor 11
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TLR11 mRNA
CTD
PMID:27935865
NCBI chr15:23,545,408...23,549,849
Ensembl chr15:23,545,408...23,549,849
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Tm4sf19
transmembrane 4 L six family member 19
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of TM4SF19 mRNA
CTD
PMID:27935865
NCBI chr11:68,372,945...68,386,192
Ensembl chr11:68,371,647...68,384,591
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Tmem132c
transmembrane protein 132C
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TMEM132C mRNA
CTD
PMID:27935865
NCBI chr12:29,115,213...29,437,900
Ensembl chr12:29,116,467...29,437,870
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Tmem177
transmembrane protein 177
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of TMEM177 mRNA
CTD
PMID:20847119
NCBI chr13:31,023,893...31,027,368
Ensembl chr13:31,023,455...31,027,378
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Tmem182
transmembrane protein 182
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TMEM182 mRNA
CTD
PMID:27935865
NCBI chr 9:43,059,432...43,111,318
Ensembl chr 9:43,059,439...43,111,317
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Tmem200b
transmembrane protein 200B
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TMEM200B mRNA
CTD
PMID:27935865
NCBI chr 5:144,107,795...144,110,551
Ensembl chr 5:144,103,550...144,112,506
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Tmem213
transmembrane protein 213
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of TMEM213 mRNA
CTD
PMID:27935865
NCBI chr 4:66,825,040...66,831,070
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Tmem252
transmembrane protein 252
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of TMEM252 mRNA
CTD
PMID:27935865
NCBI chr 1:222,316,982...222,321,946
Ensembl chr 1:222,316,795...222,321,943
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Tmem91
transmembrane protein 91
increases expression
ISO
Pioglitazone results in increased expression of TMEM91 mRNA
CTD
PMID:30031879
NCBI chr 1:81,179,483...81,187,005
Ensembl chr 1:81,179,156...81,185,164
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Tmod1
tropomodulin 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TMOD1 mRNA
CTD
PMID:27935865
NCBI chr 5:60,316,445...60,393,957
Ensembl chr 5:60,338,512...60,393,956
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Tmod4
tropomodulin 4
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TMOD4 mRNA
CTD
PMID:27935865
NCBI chr 2:182,695,709...182,700,540
Ensembl chr 2:182,695,709...182,700,540
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Tnf
tumor necrosis factor
multiple interactions affects expression decreases expression
ISO EXP
Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of CPT1A mRNA]; Pioglitazone affects the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] affects the expression of SCD mRNA]; Pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of and results in increased activity of BACE1 protein]; Pioglitazone inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased metabolism of and results in increased secretion of APP protein alternative form]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in decreased expression of CD36 mRNA]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CCL2 protein]; Pioglitazone inhibits the reaction [[osteum co-treated with Palmitic Acid co-treated with Glucose co-treated with INS protein co-treated with TNF protein co-treated with IL1B protein co-treated with TNF protein] results in increased secretion of CXCL5 protein]; Pioglitazone inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIB protein] 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Pioglitazone inhibits the reaction [Quinolinic Acid results in increased expression of TNF protein]]; [naringin co-treated with Pioglitazone] inhibits the reaction [Quinolinic Acid results in increased expression of TNF mRNA]; Fenofibrate promotes the reaction [Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of TNF protein]]; Pioglitazone inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of TNF protein]; Pioglitazone inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA]; Pioglitazone inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of TNF protein]; Pioglitazone inhibits the reaction [Cisplatin results in increased expression of TNF mRNA]; Pioglitazone inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; Pioglitazone inhibits the reaction [Fructose results in increased secretion of TNF protein]; Pioglitazone inhibits the reaction [propionic acid results in increased expression of TNF protein]; Pioglitazone inhibits the reaction [Quinolinic Acid results in increased expression of TNF mRNA]; Pioglitazone inhibits the reaction [Quinolinic Acid results in increased expression of TNF protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Pioglitazone promotes the reaction [Fenofibrate inhibits the reaction [Doxorubicin results in increased expression of TNF protein]] [Pioglitazone co-treated with Buthionine Sulfoximine] results in increased expression of TNF mRNA; Pioglitazone inhibits the reaction [Sodium Glutamate results in increased expression of TNF mRNA] pioglitazone affects the expression of TNF protein Pioglitazone results in decreased expression of TNF mRNA
CTD
PMID:14586007 PMID:15318101 PMID:17055343 PMID:20450929 PMID:22989705 PMID:25679220 PMID:27918843 PMID:28263783 PMID:28744220 PMID:29233026 PMID:30130594 PMID:30343038 PMID:31348919 PMID:32613381 PMID:36988379 PMID:37044004 More...
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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Tnfaip6
TNF alpha induced protein 6
increases expression
ISO
Pioglitazone results in increased expression of TNFAIP6 mRNA
CTD
PMID:32816093
NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649
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Tnfrsf11b
TNF receptor superfamily member 11B
multiple interactions
ISO
Pioglitazone promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in decreased secretion of TNFRSF11B protein]
CTD
PMID:31016361
NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538
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Tnfrsf1b
TNF receptor superfamily member 1B
increases secretion
ISO
Pioglitazone results in increased secretion of TNFRSF1B protein
CTD
PMID:27918843
NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
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Tnnc2
troponin C2, fast skeletal type
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TNNC2 mRNA
CTD
PMID:27935865
NCBI chr 3:153,513,272...153,516,033
Ensembl chr 3:153,513,271...153,516,029
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Tnni2
troponin I2, fast skeletal type
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TNNI2 mRNA
CTD
PMID:27935865
NCBI chr 1:197,595,012...197,597,554
Ensembl chr 1:197,594,813...197,597,560
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Tnnt1
troponin T1, slow skeletal type
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TNNT1 mRNA
CTD
PMID:27935865
NCBI chr 1:69,306,362...69,316,721
Ensembl chr 1:69,306,362...69,316,721
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Tnnt3
troponin T3, fast skeletal type
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TNNT3 mRNA
CTD
PMID:27935865
NCBI chr 1:197,652,535...197,669,736
Ensembl chr 1:197,652,431...197,669,535
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Tpi1
triosephosphate isomerase 1
decreases expression
ISO
pioglitazone results in decreased expression of TPI1 mRNA
CTD
PMID:20723549
NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
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Trarg1
trafficking regulator of GLUT4 (SLC2A4) 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of TRARG1 mRNA
CTD
PMID:27935865
NCBI chr10:61,521,107...61,541,494
Ensembl chr10:61,521,107...61,541,494
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Trdn
triadin
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TRDN mRNA
CTD
PMID:27935865
NCBI chr 1:23,955,651...24,410,494
Ensembl chr 1:23,955,651...24,410,595
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Treml1
triggering receptor expressed on myeloid cells-like 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TREML1 mRNA
CTD
PMID:27935865
NCBI chr 9:12,635,584...12,642,324
Ensembl chr 9:12,635,590...12,642,347
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Trib3
tribbles pseudokinase 3
decreases expression multiple interactions
ISO
Pioglitazone results in decreased expression of TRIB3 mRNA Pioglitazone inhibits the reaction [Arsenic Trioxide results in increased expression of TRIB3 mRNA]
CTD
PMID:32929351
NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
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Tril
TLR4 interactor with leucine-rich repeats
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TRIL mRNA
CTD
PMID:27935865
NCBI chr 4:82,922,327...82,927,172
Ensembl chr 4:82,922,328...82,927,172
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Trim54
tripartite motif-containing 54
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TRIM54 mRNA
CTD
PMID:27935865
NCBI chr 6:25,239,340...25,258,511
Ensembl chr 6:25,239,340...25,258,511
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Trpc3
transient receptor potential cation channel, subfamily C, member 3
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TRPC3 mRNA
CTD
PMID:27935865
NCBI chr 2:119,481,313...119,619,333
Ensembl chr 2:119,481,400...119,558,855
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Ttc41
tetratricopeptide repeat domain 41
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with Pioglitazone] results in decreased expression of TTC41 mRNA
CTD
PMID:27935865
NCBI chr 7:21,124,909...21,188,191
Ensembl chr 7:21,125,105...21,188,189
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Ttn
titin
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TTN mRNA
CTD
PMID:27935865
NCBI chr 3:61,652,432...61,924,912
Ensembl chr 3:61,652,439...61,924,741
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Tubb3
tubulin, beta 3 class III
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of TUBB3 mRNA
CTD
PMID:27935865
NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
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Txlnb
taxilin beta
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of TXLNB mRNA
CTD
PMID:27935865
NCBI chr 1:12,404,845...12,449,977
Ensembl chr 1:12,404,859...12,449,975
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Ube2u
ubiquitin conjugating enzyme E2 U
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of UBE2U mRNA
CTD
PMID:27935865
NCBI chr 5:115,118,234...115,187,296
Ensembl chr 5:115,118,495...115,186,874
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Ugt1a1
UDP glucuronosyltransferase family 1 member A1
increases expression
ISO
Pioglitazone results in increased expression of UGT1A1 mRNA
CTD
PMID:31233785
NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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Ulk1
unc-51 like autophagy activating kinase 1
increases expression multiple interactions
ISO
Pioglitazone results in increased expression of ULK1 mRNA [Metformin co-treated with Pioglitazone] results in increased expression of ULK1 mRNA
CTD
PMID:32589349
NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966
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Ulk2
unc-51 like autophagy activating kinase 2
increases expression
ISO
Pioglitazone results in increased expression of ULK2 mRNA
CTD
PMID:32589349
NCBI chr10:46,451,578...46,530,462
Ensembl chr10:46,454,030...46,530,407
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Umps
uridine monophosphate synthetase
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of UMPS mRNA
CTD
PMID:20847119
NCBI chr11:66,806,107...66,816,520
Ensembl chr11:66,806,045...66,821,903
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Unc45b
unc-45 myosin chaperone B
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of UNC45B mRNA
CTD
PMID:27935865
NCBI chr10:67,845,464...67,873,143
Ensembl chr10:67,845,462...67,873,389
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Usp13
ubiquitin specific peptidase 13
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of USP13 mRNA
CTD
PMID:27935865
NCBI chr 2:115,576,912...115,689,153
Ensembl chr 2:115,577,091...115,686,222
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Vasn
vasorin
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of VASN mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of VASN mRNA]
CTD
PMID:20847119
NCBI chr10:10,917,750...10,928,259
Ensembl chr10:10,917,605...10,928,357
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Vat1l
vesicle amine transport 1-like
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of VAT1L mRNA
CTD
PMID:27935865
NCBI chr19:42,194,511...42,363,835
Ensembl chr19:42,194,533...42,363,831
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Vcam1
vascular cell adhesion molecule 1
multiple interactions
ISO EXP
pioglitazone inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of VCAM1 protein] Pioglitazone inhibits the reaction [[Dietary Fats co-treated with Fructose] results in increased expression of VCAM1 protein]; Pioglitazone inhibits the reaction [Streptozocin results in increased expression of VCAM1 mRNA]
CTD
PMID:16979161 PMID:17015710 PMID:30343038
NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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Vegfa
vascular endothelial growth factor A
multiple interactions decreases expression increases expression
ISO EXP
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of VEGFA mRNA; pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of VEGFA mRNA] pioglitazone results in decreased expression of VEGFA protein pioglitazone inhibits the reaction [Dietary Fats results in increased expression of VEGFA mRNA] Pioglitazone results in increased expression of VEGFA mRNA
CTD
PMID:20847119 PMID:22456468 PMID:26281317 PMID:32589349
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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Vegfb
vascular endothelial growth factor B
increases expression
ISO
Pioglitazone results in increased expression of VEGFB mRNA
CTD
PMID:32589349
NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944
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Vldlr
very low density lipoprotein receptor
increases expression
ISO
pioglitazone results in increased expression of VLDLR mRNA Pioglitazone results in increased expression of VLDLR mRNA
CTD
PMID:19706614 PMID:30031879
NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920
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Vtn
vitronectin
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of VTN mRNA
CTD
PMID:27935865
NCBI chr10:63,394,732...63,397,812
Ensembl chr10:63,394,719...63,397,810
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Vwa2
von Willebrand factor A domain containing 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in increased expression of VWA2 mRNA
CTD
PMID:27935865
NCBI chr 1:255,922,263...255,963,920
Ensembl chr 1:255,923,541...255,963,934
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Wfdc13
WAP four-disulfide core domain 13
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of WFDC13 mRNA
CTD
PMID:27935865
NCBI chr 3:153,419,553...153,421,306
Ensembl chr 3:153,419,648...153,421,221
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Wfdc18
WAP four-disulfide core domain 18
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of WFDC18 mRNA
CTD
PMID:27935865
NCBI chr10:68,588,818...68,590,972
Ensembl chr10:68,588,818...68,589,671
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Wnt2b
Wnt family member 2B
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of WNT2B mRNA
CTD
PMID:27935865
NCBI chr 2:192,454,226...192,468,599
Ensembl chr 2:192,453,824...192,470,308
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Wscd2
WSC domain containing 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of WSCD2 mRNA
CTD
PMID:27935865
NCBI chr12:43,046,547...43,141,115
Ensembl chr12:43,048,043...43,088,591
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Xcr1
X-C motif chemokine receptor 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of XCR1 mRNA
CTD
PMID:27935865
NCBI chr 8:123,479,454...123,516,168
Ensembl chr 8:123,479,590...123,487,226
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Xirp1
xin actin-binding repeat containing 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of XIRP1 mRNA
CTD
PMID:27935865
NCBI chr 8:119,744,778...119,757,547
Ensembl chr 8:119,747,419...119,757,349
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Xirp2
xin actin-binding repeat containing 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of XIRP2 mRNA
CTD
PMID:27935865
NCBI chr 3:52,126,213...52,213,094
Ensembl chr 3:51,870,092...52,213,091
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Xrcc1
X-ray repair cross complementing 1
multiple interactions
ISO
Pioglitazone inhibits the reaction [LEPR protein affects the expression of XRCC1 protein]
CTD
PMID:35472412
NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
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Yipf7
Yip1 domain family, member 7
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of YIPF7 mRNA
CTD
PMID:27935865
NCBI chr14:38,571,045...38,599,070
Ensembl chr14:38,571,066...38,599,055
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Zc3h11a
zinc finger CCCH-type containing 11A
multiple interactions
ISO
pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in increased expression of ZC3H11A mRNA]
CTD
PMID:20847119
NCBI chr13:45,073,422...45,113,901
Ensembl chr13:45,071,718...45,114,009
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Zcwpw1
zinc finger CW-type and PWWP domain containing 1
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ZCWPW1 mRNA
CTD
PMID:27935865
NCBI chr12:18,880,625...18,910,713
Ensembl chr12:18,880,633...18,910,711
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Zdbf2
zinc finger, DBF-type containing 2
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ZDBF2 mRNA
CTD
PMID:27935865
NCBI chr 9:64,672,974...64,748,446
Ensembl chr 9:64,709,880...64,744,265
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Zfp354c
zinc finger protein 354C
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ZFP354C mRNA
CTD
PMID:27935865
NCBI chr10:35,129,720...35,145,717
Ensembl chr10:35,132,959...35,145,661
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Zfp36
zinc finger protein 36
multiple interactions
ISO
[pioglitazone co-treated with tert-Butylhydroperoxide] results in increased expression of ZFP36 mRNA
CTD
PMID:20847119
NCBI chr 1:83,669,084...83,671,564
Ensembl chr 1:83,669,084...83,671,564
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Zfp385c
zinc finger protein 385C
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ZFP385C mRNA
CTD
PMID:27935865
NCBI chr10:85,562,003...85,618,100
Ensembl chr10:85,562,820...85,582,986
G
Zfp521
zinc finger protein 521
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ZFP521 mRNA
CTD
PMID:27935865
NCBI chr18:4,775,952...5,068,592
Ensembl chr18:4,787,295...5,068,458
G
Zfp641
zinc finger protein 641
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ZFP641 mRNA
CTD
PMID:27935865
NCBI chr 7:129,434,576...129,444,847
Ensembl chr 7:129,434,576...129,444,644
G
Zkscan4
zinc finger with KRAB and SCAN domains 4
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ZKSCAN4 mRNA
CTD
PMID:27935865
NCBI chr17:43,104,853...43,113,101
Ensembl chr17:43,106,370...43,113,183
G
Znf454
zinc finger protein 454
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ZFP454 mRNA
CTD
PMID:27935865
NCBI chr10:35,183,729...35,200,450
Ensembl chr10:35,185,028...35,245,505
G
Zpbp
zona pellucida binding protein
multiple interactions
ISO
[N-nitroso-tris-chloroethylurea co-treated with pioglitazone] results in decreased expression of ZPBP mRNA
CTD
PMID:27935865
NCBI chr14:85,830,971...86,030,778
Ensembl chr14:85,833,548...86,033,095
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