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ONTOLOGY REPORT - ANNOTATIONS


Term:cyproterone acetate
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Accession:CHEBI:50743 term browser browse the term
Definition:A chlorinated steroid that has formula C24H29ClO4.
Synonyms:exact_synonym: 6-chloro-3,20-dioxo-1beta,2beta-dihydro-3'H-cyclopropa[1,2]pregna-4,6-dien-17-yl acetate
 related_synonym: Cyproterone 17-O-acetate;   Formula=C24H29ClO4;   InChI=1S/C24H29ClO4/c1-12(26)24(29-13(2)27)8-6-16-14-10-20(25)19-11-21(28)15-9-18(15)23(19,4)17(14)5-7-22(16,24)3/h10-11,14-18H,5-9H2,1-4H3/t14-,15+,16-,17-,18-,22-,23-,24-/m0/s1;   InChIKey=UWFYSQMTEOIJJG-FDTZYFLXSA-N;   SMILES=[H][C@@]12C[C@]1([H])[C@@]1(C)C(=CC2=O)C(Cl)=C[C@@]2([H])[C@]3([H])CC[C@](OC(C)=O)(C(C)=O)[C@@]3(C)CC[C@]12[H];   acetic acid (8R,9S,10S,13S,14S,17R)-17-acetyl-6-(S)-chloro-10,13-dimethyl-3-(R)-oxo-1,2,3,8,9,10,11,12,13,14,15,16,17,20-tetradecahydro-cyclopropa[1,2]cyclopenta[a]phenanthren-17-yl ester
 alt_id: CHEBI:31451;   CHEBI:336019;   CHEBI:47297
 xref: Beilstein:2342172 "Beilstein";   CAS:427-51-0 "ChemIDplus";   DrugBank:DB04839;   Drug_Central:766 "DrugCentral";   KEGG:D01368
 xref_mesh: MESH:D017373
 xref: PDBeChem:CA4;   Patent:DE1189991;   Patent:US3234093;   Wikipedia:Cyproterone_Acetate


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cyproterone acetate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:6480464
G Apoa1 apolipoprotein A1 JBrowse link 8 50,525,091 50,526,875 RGD:6480464
G Apoa2 apolipoprotein A2 JBrowse link 13 89,596,872 89,598,805 RGD:6480464
G Ar androgen receptor JBrowse link X 67,656,253 67,828,998 RGD:6480464
G Bloc1s1 biogenesis of lysosomal organelles complex-1, subunit 1 JBrowse link 7 3,342,630 3,346,238 RGD:6480464
G Brd8 bromodomain containing 8 JBrowse link 18 27,375,645 27,423,989 RGD:6480464
G Ccr1 C-C motif chemokine receptor 1 JBrowse link 8 132,996,646 133,002,201 RGD:6480464
G Ccr5 C-C motif chemokine receptor 5 JBrowse link 8 133,192,398 133,215,599 RGD:6480464
G Chd9 chromodomain helicase DNA binding protein 9 JBrowse link 19 17,364,969 17,517,757 RGD:6480464
G Cnot1 CCR4-NOT transcription complex, subunit 1 JBrowse link 19 9,668,186 9,761,605 RGD:6480464
G Crebbp CREB binding protein JBrowse link 10 11,590,994 11,721,039 RGD:6480464
G Crp C-reactive protein JBrowse link 13 91,080,448 91,081,358 RGD:6480464
G Cxcr3 C-X-C motif chemokine receptor 3 JBrowse link X 71,614,346 71,616,997 RGD:6480464
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 JBrowse link 7 99,142,431 99,183,540 RGD:6480464
G Cyp2c24 cytochrome P450, family 2, subfamily c, polypeptide 24 JBrowse link 1 258,074,797 258,139,176 RGD:6480464
G Dhx30 DExH-box helicase 30 JBrowse link 8 118,160,315 118,194,674 RGD:6480464
G Egf epidermal growth factor JBrowse link 2 68,820,616 68,895,537 RGD:6480464
G Ep300 E1A binding protein p300 JBrowse link 7 122,818,194 122,889,055 RGD:6480464
G Fabp4 fatty acid binding protein 4 JBrowse link 2 93,792,666 93,797,267 RGD:6480464
G Fshb follicle stimulating hormone subunit beta JBrowse link 3 98,088,321 98,092,131 RGD:6480464
G Gnaq G protein subunit alpha q JBrowse link 1 233,382,778 233,622,584 RGD:6480464
G Greb1 growth regulating estrogen receptor binding 1 JBrowse link 6 41,932,941 42,002,770 RGD:6480464
G Helz2 helicase with zinc finger 2 JBrowse link 3 176,730,024 176,744,382 RGD:6480464
G Igf1 insulin-like growth factor 1 JBrowse link 7 28,412,123 28,491,815 RGD:6480464
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:6480464
G Itgb3bp integrin subunit beta 3 binding protein JBrowse link 5 118,476,410 118,541,928 RGD:6480464
G Kif11 kinesin family member 11 JBrowse link 1 256,035,866 256,088,299 RGD:6480464
G Kpna1 karyopherin subunit alpha 1 JBrowse link 11 67,652,573 67,717,180 RGD:6480464
G Kpna2 karyopherin subunit alpha 2 JBrowse link 10 95,200,029 95,212,111 RGD:6480464
G Kpna3 karyopherin subunit alpha 3 JBrowse link 15 41,696,356 41,770,112 RGD:6480464
G Kpna4 karyopherin subunit alpha 4 JBrowse link 2 165,684,345 165,739,874 RGD:6480464
G Kpna5 karyopherin subunit alpha 5 JBrowse link 20 32,509,573 32,573,591 RGD:6480464
G Lhb luteinizing hormone subunit beta JBrowse link 1 101,409,992 101,413,725 RGD:6480464
G Med1 mediator complex subunit 1 JBrowse link 10 86,101,560 86,145,271 RGD:6480464
G Men1 menin 1 JBrowse link 1 221,704,394 221,710,343 RGD:6480464
G Mta1 metastasis associated 1 JBrowse link 6 137,911,302 137,950,066 RGD:6480464
G Myc MYC proto-oncogene, bHLH transcription factor JBrowse link 7 102,586,313 102,591,240 RGD:6480464
G Ncoa1 nuclear receptor coactivator 1 JBrowse link 6 28,677,563 28,931,844 RGD:6480464
G Ncoa2 nuclear receptor coactivator 2 JBrowse link 5 5,466,544 5,696,540 RGD:6480464
G Ncoa3 nuclear receptor coactivator 3 JBrowse link 3 162,692,176 162,788,582 RGD:6480464
G Ncor1 nuclear receptor co-repressor 1 JBrowse link 10 48,629,121 48,772,890 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nfkbib NFKB inhibitor beta JBrowse link 1 86,941,073 86,948,845 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 JBrowse link X 54,734,385 54,738,513 RGD:6480464
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 JBrowse link 5 151,776,004 151,779,319 RGD:6480464
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 JBrowse link 13 89,585,072 89,591,278 RGD:6480464
G Nrbf2 nuclear receptor binding factor 2 JBrowse link 20 22,728,145 22,746,477 RGD:6480464
G Nrip1 nuclear receptor interacting protein 1 JBrowse link 11 14,658,225 14,742,478 RGD:6480464
G Pa2g4 proliferation-associated 2G4 JBrowse link 7 2,979,587 2,987,055 RGD:6480464
G Pde5a phosphodiesterase 5A JBrowse link 2 226,899,604 227,044,916 RGD:6480464
G Pelp1 proline, glutamate and leucine rich protein 1 JBrowse link 10 56,988,076 57,005,111 RGD:6480464
G Pgr progesterone receptor JBrowse link 8 7,128,656 7,187,796 RGD:6480464
G Pnrc2 proline-rich nuclear receptor coactivator 2 JBrowse link 5 154,220,552 154,223,536 RGD:6480464
G Pprc1 PPARG related coactivator 1 JBrowse link 1 265,809,892 265,826,319 RGD:6480464
G Prame preferentially expressed antigen in melanoma JBrowse link X 106,082,984 106,091,256 RGD:6480464
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464
G Prlr prolactin receptor JBrowse link 2 60,131,410 60,325,686 RGD:6480464
G Tfrc transferrin receptor JBrowse link 11 71,397,423 71,419,263 RGD:6480464
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 JBrowse link 1 199,664,039 199,670,970 RGD:6480464
G Trerf1 transcriptional regulating factor 1 JBrowse link 9 15,653,230 15,881,695 RGD:6480464
G Ube3a ubiquitin protein ligase E3A JBrowse link 1 116,586,901 116,678,161 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    chemical entity 19677
      group 19592
        organic group 18351
          3-oxo-Delta(4)-steroid group 7907
            3-oxo-Delta(4) steroid 7907
              cyproterone acetate 62
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            organic group 18351
                              organic divalent group 18340
                                organodiyl group 18340
                                  carbonyl group 18225
                                    carbonyl compound 18225
                                      ketone 15788
                                        oxyketone 8441
                                          alpha-oxyketone 8441
                                            alpha-hydroxy ketone 8441
                                              tertiary alpha-hydroxy ketone 8261
                                                cyproterone 64
                                                  cyproterone acetate 62
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.