The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.
Foscarnet inhibits the reaction [SLC16A1 protein results in increased transport of Benzoic Acid] SLC16A1 protein results in increased import of Foscarnet
Foscarnet results in decreased activity of SLC20A1 protein Foscarnet results in increased expression of SLC20A1 mRNA Foscarnet inhibits the reaction [Phosphates results in increased expression of SLC20A1 mRNA]
Foscarnet inhibits the reaction [Calcium results in increased expression of SLC23A2 mRNA]; Foscarnet inhibits the reaction [Phosphates results in increased expression of SLC23A2 mRNA]
Foscarnet inhibits the reaction [Calcium results in increased expression of SPP1 mRNA]; Foscarnet inhibits the reaction [Phosphates results in increased expression of SPP1 mRNA]; Foscarnet inhibits the reaction [Phosphates results in increased expression of SPP1 protein]