RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: severe acute respiratory syndrome
Accession: DOID:2945
browse the term
Definition: A Coronavirus infectious disease that results_in infection located_in respiratory tract, has_material_basis_in SARS coronavirus (SARS-CoV), which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia. (DO)
Synonyms: exact_synonym: SARS; SARS (Severe Acute Respiratory Syndrome); SARS-CoV infection
primary_id: MESH:D045169
xref: EFO:0000694 ; GARD:9237 ; ICD10CM:J12.81 ; ICD9CM:079.82 ; NCI:C85064
For additional species annotation, visit the
Alliance of Genome Resources .
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Abo
ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
susceptibility
ISO
RGD
PMID:15784866
RGD:5128832
NCBI chr 3:10,162,087...10,182,835
Ensembl chr 3:10,162,096...10,191,423
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Ace
angiotensin I converting enzyme
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:15381116
NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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Ace2
angiotensin converting enzyme 2
treatment susceptibility severity
ISO
CTD Direct Evidence: marker/mechanism mRNA, protein:decreased expression:heart (mouse) human gene in a mouse model
CTD RGD
PMID:14647384 PMID:16007097 PMID:16166518 PMID:16339146 PMID:19453650 PMID:19625462 PMID:23678171 PMID:24172901 PMID:24227843 PMID:26801988 PMID:31996437 PMID:32092392 PMID:32201080 PMID:19453650 PMID:32553273 PMID:17974127 PMID:16007097 More...
RGD:40818405 , RGD:32716426 , RGD:30309965 , RGD:30309202
NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
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Anpep
alanyl aminopeptidase, membrane
disease_progression
ISO
mRNA:increased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789
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Bpi
bactericidal/permeability-increasing protein
disease_progression
ISO
mRNA:increased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr 3:146,909,626...146,936,487
Ensembl chr 3:146,909,629...146,936,221
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C1qb
complement C1q B chain
disease_progression
ISO
mRNA:increased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407
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C5ar1
complement C5a receptor 1
disease_progression
ISO
mRNA:increased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr 1:76,948,622...76,959,826
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Casp3
caspase 3
disease_progression
ISO
mRNA:increased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp9
caspase 9
disease_progression
ISO
mRNA:increased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Ccl1
C-C motif chemokine ligand 1
ISO
mRNA: increased expression:lung (mouse)
RGD
PMID:15356152
RGD:30309221
NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159
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Ccl2
C-C motif chemokine ligand 2
treatment severity
ISO
CTD Direct Evidence: marker/mechanism protein:increased expression:bronchoalveolar lavage (human) protein:increased expression:serum (human) mRNA, protein: increased expression, altered expression:lung (mouse) protein:increased expression:plasma (human)
CTD RGD
PMID:20484496 PMID:15888207 PMID:32553273 PMID:15602737 PMID:15356152 PMID:15781938 PMID:15657466 PMID:16195357 More...
RGD:34201108 , RGD:32716426 , RGD:32716399 , RGD:30309221 , RGD:30309220 , RGD:30309219 , RGD:30309218
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccl3
C-C motif chemokine ligand 3
ISO
mRNA, protein: increased expression, altered expression:lung (mouse)
RGD
PMID:15356152
RGD:30309221
NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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Ccl5
C-C motif chemokine ligand 5
severity treatment
ISO
Severe Acute Respiratory Syndrome; DNA:transversion:5' utr:-28C>G (human) protein:increased expression:bronchoalveolar lavage (human) mRNA, protein: increased expression, altered expression:lung, brain (mouse) protein:increased expression:plasma (human) mRNA:increased expression:lung (mouse)
RGD
PMID:19258635 PMID:15888207 PMID:15865221 PMID:32553273 PMID:15356152 PMID:15781938 PMID:16195357 PMID:32365944 More...
RGD:4891448 , RGD:34201108 , RGD:33769580 , RGD:32716426 , RGD:30309221 , RGD:30309220 , RGD:30309218 , RGD:30309207
NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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Ccr1
C-C motif chemokine receptor 1
ISO
mRNA:increased expression:lung (mouse)
RGD
PMID:15356152
RGD:30309221
NCBI chr 8:123,556,286...123,561,841
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Ccr3
C-C motif chemokine receptor 3
ISO
mRNA:altered expression:lung (mouse)
RGD
PMID:15356152
RGD:30309221
NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990
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Cd14
CD14 molecule
disease_progression
ISO
mRNA:increased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261
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Cd3e
CD3 epsilon subunit of T-cell receptor complex
ISO
protein:increased expression:Tcell, testis (human)
RGD
PMID:16237152
RGD:27372876
NCBI chr 8:45,303,848...45,315,005
Ensembl chr 8:45,303,852...45,315,022
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Cd4
Cd4 molecule
disease_progression
ISO
mRNA:increased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr 4:157,668,878...157,695,366
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Cd68
Cd68 molecule
disease_progression
ISO
mRNA, protein:increased expression:lung (human) protein:increased expression:macrophage, testis (human)
RGD
PMID:19635508 PMID:16237152
RGD:5490168 , RGD:27372876
NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
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Cd9
CD9 molecule
disease_progression
ISO
mRNA, protein:increased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
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Clcf1
cardiotrophin-like cytokine factor 1
disease_progression
ISO
mRNA:decreased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605
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Clec4m
C-type lectin domain family 4 member M
susceptibility no_association
ISO
DNA:repeats:exon 4:
RGD
PMID:16369534 PMID:18708672 PMID:17534355 PMID:17534354
RGD:35673327 , RGD:36049808 , RGD:36049807 , RGD:36049806
NCBI chr12:1,915,902...1,924,529
Ensembl chr12:1,915,919...1,924,539
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Ctsl
cathepsin L
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:16081529 PMID:16339146 PMID:22496216 PMID:23678171
NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548
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Cxcl1
C-X-C motif chemokine ligand 1
IEP
protein:increased expression:respiratory system fluid/secretion
RGD
PMID:19741068
RGD:4143520
NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215
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Cxcl10
C-X-C motif chemokine ligand 10
treatment severity disease_progression
ISO
protein:increased expression:serum protein:increased expression:serum (human) mRNA, protein: increased expression, altered expression:lung (mouse) mRNA, protein:increased expression:serum, lung (human) mRNA, protein:increased expression:plasma, lung (human) protein:increased expression:lung (human) protein:increased expression:lung (mouse) mRNA:increased expression:lung (mouse) mRNA:decreased expression:lung (human)
RGD
PMID:17052299 PMID:15865221 PMID:32553273 PMID:15602737 PMID:15356152 PMID:15781938 PMID:15657466 PMID:16195357 PMID:17129463 PMID:20231782 PMID:32365944 PMID:19635508 More...
RGD:5135440 , RGD:33769580 , RGD:32716426 , RGD:32716399 , RGD:30309221 , RGD:30309220 , RGD:30309219 , RGD:30309218 , RGD:30309217 , RGD:30309216 , RGD:30309207 , RGD:5490168
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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Cxcl11
C-X-C motif chemokine ligand 11
treatment
ISO
RGD
PMID:32553273
RGD:32716426
NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271
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Cxcl3
C-X-C motif chemokine ligand 3
ISO
mRNA:altered expression:lung (mouse)
RGD
PMID:32364527
RGD:27226699
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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Cxcl6
C-X-C motif chemokine ligand 6
IEP
protein:increased expression:respiratory fluid/secretion
RGD
PMID:19741068
RGD:4143520
NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
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Cxcl9
C-X-C motif chemokine ligand 9
severity treatment
ISO
mRNA, protein:increased expression:lung protein:increased expression:bronchoalveolar lavage (human) protein:increased expression:plasma (human) protein:increased expression:serum (human) mRNA, protein: increased expression, altered expression:lung (mouse)
RGD
PMID:19906920 PMID:15888207 PMID:16195357 PMID:15602737 PMID:15356152 PMID:15781938 More...
RGD:4891446 , RGD:34201108 , RGD:30309218 , RGD:32716399 , RGD:30309221 , RGD:30309220
NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
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Cxcr3
C-X-C motif chemokine receptor 3
ISO
mRNA:altered expression:lung (mouse)
RGD
PMID:15356152
RGD:30309221
NCBI chr X:66,844,318...66,846,969
Ensembl chr X:66,844,318...66,846,969
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Egfr
epidermal growth factor receptor
severity
ISO
RGD
PMID:28404843
RGD:38599178
NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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Fgb
fibrinogen beta chain
ISO
protein:increased expression:lung (mouse)
RGD
PMID:23919993
RGD:30310231
NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
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Fgf7
fibroblast growth factor 7
disease_progression
ISO
mRNA:increased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
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Fgg
fibrinogen gamma chain
ISO
protein:increased expression:lung (mouse)
RGD
PMID:23919993
RGD:30310231
NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322
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Fn1
fibronectin 1
ISO
protein:increased expression:lung (mouse)
RGD
PMID:23919993
RGD:30310231
NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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Fshb
follicle stimulating hormone subunit beta
ISO
protein:increased expression:adenohypophysis (human)
RGD
PMID:20651845
RGD:28711759
NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
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Gh1
growth hormone 1
ISO
protein:decreased expression:adenohypophysis (human)
RGD
PMID:20651845
RGD:28711759
NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
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Hp
haptoglobin
disease_progression
ISO
mRNA:increased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
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Ifna1
interferon, alpha 1
ISO
CTD Direct Evidence: therapeutic
CTD
PMID:15200845
NCBI chr 5:103,097,356...103,097,925
Ensembl chr 5:103,097,356...103,097,925
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Ifnb1
interferon beta 1
treatment
ISO
CTD Direct Evidence: marker/mechanism|therapeutic
CTD RGD
PMID:15200845 PMID:26861016 PMID:32553273
RGD:32716426
NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523
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Ifng
interferon gamma
susceptibility treatment
ISO
DNA:polymorphism:cds:+874A>T(human) protein:increased expression:peripheral blood mononuclear cells (human) protein:increased expression:serum (human) DNA:SNP:intron:+874A>T (rs2430561)(human)
RGD
PMID:19258635 PMID:15865221 PMID:16781892 PMID:15602737 PMID:16672072 PMID:19526193 PMID:17872527 More...
RGD:4891448 , RGD:33769580 , RGD:32716400 , RGD:32716399 , RGD:32716398 , RGD:32716397 , RGD:32716396
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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Igf1
insulin-like growth factor 1
disease_progression
ISO
mRNA:increased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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Il10
interleukin 10
treatment
IEP ISO
protein:increased expression:serum, bronchoalveolar Lavage fluid (rat)
RGD
PMID:16409721 PMID:15865221
RGD:32726073 , RGD:33769580
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Il18
interleukin 18
ISO
protein:increased expression:serum (human)
RGD
PMID:15602737
RGD:32716399
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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Il1a
interleukin 1 alpha
ISO
mRNA:altered expression:lung (mouse)
RGD
PMID:32364527
RGD:27226699
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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Il1b
interleukin 1 beta
severity
ISO
mRNA:altered expression:lung (mouse) mRNA, protein:increased expression:lung, bronchoalveolar lavage (mouse)
RGD
PMID:32364527 PMID:32365944
RGD:27226699 , RGD:30309207
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il1r1
interleukin 1 receptor type 1
disease_progression
ISO
mRNA:increased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
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Il23a
interleukin 23 subunit alpha
ISO
mRNA:decreased expression:lung (mouse)
RGD
PMID:32364527
RGD:27226699
NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
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Il6
interleukin 6
severity disease_progression treatment
ISO IEP
protein:increased expression:serum (human) protein:increased expression:blood (human) protein:increased expression:bronchoalveolar lavage (human) protein:increased expression:serum, Bronchoalveolar Lavage fluid (rat)
RGD
PMID:15657466 PMID:15472864 PMID:15888207 PMID:15865221 PMID:16409721 PMID:32553273 PMID:15271897 More...
RGD:30309219 , RGD:34888224 , RGD:34201108 , RGD:33769580 , RGD:32726073 , RGD:32716426 , RGD:32716401
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Il7
interleukin 7
ISO
mRNA:decreased expression:lung (mouse)
RGD
PMID:32364527
RGD:27226699
NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
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Irf3
interferon regulatory factor 3
disease_progression
ISO
CTD Direct Evidence: marker/mechanism mRNA:increased expression:lung (human)
CTD RGD
PMID:26861016 PMID:19635508
RGD:5490168
NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
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Itga2b
integrin subunit alpha 2b
disease_progression
ISO
mRNA:decreased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168
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Krt7
keratin 7
ISO
protein:increased expression:lung (mouse)
RGD
PMID:23919993
RGD:30310231
NCBI chr 7:132,528,881...132,545,052
Ensembl chr 7:132,528,895...132,545,052
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Lhb
luteinizing hormone subunit beta
ISO
protein:increased expression:adenohypophysis (human)
RGD
PMID:20651845
RGD:28711759
NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972 Ensembl chr 1:95,900,984...95,901,972
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Mapk1
mitogen activated protein kinase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20484496
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:20484496
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Msr1
macrophage scavenger receptor 1
disease_progression
ISO
mRNA:increased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr16:52,717,775...52,803,602
Ensembl chr16:52,717,732...52,799,676
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Myd88
MYD88, innate immune signal transduction adaptor
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26861016
NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
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Nfil3
nuclear factor, interleukin 3 regulated
disease_progression
ISO
mRNA:increased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858
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Nlrp3
NLR family, pyrin domain containing 3
ISO
RGD
PMID:32365944
RGD:30309207
NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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Pecam1
platelet and endothelial cell adhesion molecule 1
disease_progression
ISO
mRNA, protein:increased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116
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Pi4kb
phosphatidylinositol 4-kinase beta
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:22253445
NCBI chr 2:182,540,377...182,572,684
Ensembl chr 2:182,540,567...182,588,488
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Plat
plasminogen activator, tissue type
ISO
protein:increased expression:plasma (human)
RGD
PMID:16274108
RGD:30309949
NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
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Plg
plasminogen
ISO
protein:increased expression:lung (mouse)
RGD
PMID:23919993
RGD:30310231
NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786
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Pomc
proopiomelanocortin
ISO
protein:decreased expression:adenohypophysis (human)
RGD
PMID:20651845
RGD:28711759
NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
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Prl
prolactin
ISO
protein:increased expression:adenohypophysis (human)
RGD
PMID:20651845
RGD:28711759
NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
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Rab31
RAB31, member RAS oncogene family
disease_progression
ISO
mRNA:increased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr 9:105,246,712...105,382,973
Ensembl chr 9:105,246,709...105,381,253
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Rela
RELA proto-oncogene, NF-kB subunit
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26861016
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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RT1-Da
RT1 class II, locus Da
disease_progression
ISO
mRNA:increased expression:lung
RGD
PMID:19635508
RGD:5490168
NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
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RT1-Db1
RT1 class II, locus Db1
ISO
DNA:polymorphism:cds:HLA-DRB1*0301 (human) DNA:polymorphism:cds:HLA-DRB1*12 (human)
RGD
PMID:15243926 PMID:19445991
RGD:32716374 RGD:32716381
NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
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S100a8
S100 calcium binding protein A8
disease_progression
ISO
mRNA:increased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
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Serpina3n
serpin family A member 3N
ISO
protein:increased expression:plasma
RGD
PMID:16649161
RGD:5147434
NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433
G
Slpi
secretory leukocyte peptidase inhibitor
disease_progression
ISO
mRNA:increased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
G
Stat1
signal transducer and activator of transcription 1
ISS
MouseDO
NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
G
Tbk1
TANK-binding kinase 1
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26861016
NCBI chr 7:57,077,830...57,110,868
Ensembl chr 7:57,077,830...57,110,892
G
Tgfb1
transforming growth factor, beta 1
ISO IEP
protein:increased expression:serum (human) protein:increased expression:serum, bronchoalveolar Lavage fluid (rat)
RGD
PMID:15271897 PMID:16409721
RGD:32716401 , RGD:32726073
NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
G
Thbd
thrombomodulin
ISO
protein:increased expression:plasma (human)
RGD
PMID:16274108
RGD:30309949
NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193
G
Ticam2
TIR domain containing adaptor molecule 2
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26861016
NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462
G
Tirap
TIR domain containing adaptor protein
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26861016
NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432
G
Tlr2
toll-like receptor 2
disease_progression
ISO
mRNA:increased expression:lung (human)
RGD
PMID:19635508
RGD:5490168
NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630
G
Tmprss11d
transmembrane serine protease 11D
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:24227843
NCBI chr14:21,707,336...21,769,398
Ensembl chr14:21,707,336...21,769,396
G
Tmprss2
transmembrane serine protease 2
severity
ISO
RGD
PMID:30626688
RGD:30309210
NCBI chr11:36,934,306...36,973,779
Ensembl chr11:36,934,306...36,973,715
G
Tnf
tumor necrosis factor
ISO
protein:increased expression:plasma (human) protein:increased expression:bronchoalveolar lavage (human)
RGD
PMID:14514395 PMID:15888207
RGD:30309961 , RGD:34201108
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Tshb
thyroid stimulating hormone subunit beta
ISO
protein:decreased expression:adenohypophysis (human)
RGD
PMID:20651845
RGD:28711759
NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
G
Vim
vimentin
ISO
CTD Direct Evidence: marker/mechanism
CTD
PMID:26801988
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
G
Vwf
von Willebrand factor
ISO
protein:increased expression:lung (mouse)
RGD
PMID:23919993
RGD:30310231
NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
G
Xcl1
X-C motif chemokine ligand 1
ISO
mRNA:increased expression:lung (mouse)
RGD
PMID:15356152
RGD:30309221
NCBI chr13:77,248,687...77,252,343
Ensembl chr13:77,248,717...77,252,329
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